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PRJNA195909:zebrafish embryo and larva development

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Results for sp2

Z-value: 2.04

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Transcription factors associated with sp2

Gene Symbol Gene ID Gene Info
ENSDARG00000076763 sp2 transcription factor
ENSDARG00000113443 sp2 transcription factor
ENSDARG00000115477 sp2 transcription factor

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
sp2dr11_v1_chr11_-_12008001_120080010.917.0e-04Click!

Activity profile of sp2 motif

Sorted Z-values of sp2 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr20_+_33991801 5.55 ENSDART00000061744
zona pellucida glycoprotein 3a, tandem duplicate 1
chr17_-_2584423 5.04 ENSDART00000013506
zona pellucida glycoprotein 3, tandem duplicate 2
chr20_+_33987465 4.94 ENSDART00000061751
zona pellucida glycoprotein 3a, tandem duplicate 2
chr24_-_20599781 4.76 ENSDART00000179664
ENSDART00000141823
zinc finger and BTB domain containing 47b
chr22_+_835728 4.05 ENSDART00000003325
DENN/MADD domain containing 2Db
chr18_-_127558 3.47 ENSDART00000149556
transient receptor potential cation channel, subfamily M, member 7
chr20_+_54304800 3.38 ENSDART00000121661
zona pellucida glycoprotein 2, tandem duplicate 6
chr13_-_17860307 3.03 ENSDART00000135920
ENSDART00000054579
membrane-associated ring finger (C3HC4) 8
chr25_+_22319940 2.97 ENSDART00000154065
ENSDART00000153492
ENSDART00000024866
ENSDART00000154376
cytochrome P450, family 11, subfamily A, polypeptide 1
chr10_-_641609 2.89 ENSDART00000041236
regulatory factor X, 3 (influences HLA class II expression)
chr12_-_23365737 2.88 ENSDART00000170376
membrane protein, palmitoylated 7a (MAGUK p55 subfamily member 7)
chr19_+_26340736 2.78 ENSDART00000013497
myosin regulatory light chain interacting protein a
chr23_+_2740741 2.71 ENSDART00000134938
zgc:114123
chr12_+_46634736 2.69 ENSDART00000008009
tripartite motif containing 16
chr3_+_29469283 2.58 ENSDART00000103592
family with sequence similarity 83, member Fa
chr20_+_39250673 2.58 ENSDART00000153003
RALBP1 associated Eps domain containing 1
chr10_+_1849874 2.52 ENSDART00000158897
ENSDART00000149956
adenomatous polyposis coli
chr2_+_59015878 2.40 ENSDART00000148816
ENSDART00000122795
si:ch1073-391i24.1
chr18_-_127873 2.31 ENSDART00000148490
transient receptor potential cation channel, subfamily M, member 7
chr8_-_4100365 2.31 ENSDART00000142846
cut-like homeobox 2b
chr18_-_41161828 2.27 ENSDART00000114993

chr7_-_45852270 2.27 ENSDART00000170224
SHC SH2-domain binding protein 1
chr3_+_35611625 2.25 ENSDART00000190995
TNF receptor-associated factor 7
chr3_+_51684963 2.16 ENSDART00000091180
ENSDART00000183711
ENSDART00000159493
BAI1-associated protein 2a
chr15_+_25489406 2.16 ENSDART00000162482
zgc:152863
chr14_-_237130 2.14 ENSDART00000164988
biorientation of chromosomes in cell division 1-like 1
chr3_-_16227683 2.13 ENSDART00000111707
calcium channel, voltage-dependent, beta 1 subunit
chr5_-_30074332 2.13 ENSDART00000147963
beta-carotene oxygenase 2a
chr3_+_46559639 2.13 ENSDART00000146189
ENSDART00000127832
ENSDART00000151035
ribonucleoprotein, PTB-binding 1
chr16_+_25259313 2.12 ENSDART00000058938
F-box protein 32
chr23_+_2825940 2.12 ENSDART00000135781
phospholipase C, gamma 1
chr24_-_26622423 2.10 ENSDART00000182044
TRAF2 and NCK interacting kinase b
chr16_-_7793457 2.09 ENSDART00000113483
tripartite motif containing 71, E3 ubiquitin protein ligase
chr5_-_12743196 2.09 ENSDART00000188976
ENSDART00000137705
leucine-zipper-like transcription regulator 1
chr23_+_30898013 2.09 ENSDART00000146859
Cdk5 and Abl enzyme substrate 2a
chr20_-_182841 2.09 ENSDART00000064546
si:ch211-241j12.3
chr13_-_12021566 2.05 ENSDART00000125430
peroxisome proliferator-activated receptor gamma, coactivator-related 1
chr7_-_32020100 2.04 ENSDART00000185433
kinesin family member 18A
chr24_-_36593876 2.00 ENSDART00000160901

chr5_-_30080332 1.95 ENSDART00000140049
beta-carotene oxygenase 2a
chr18_+_27077853 1.92 ENSDART00000125326
ENSDART00000192660
ENSDART00000098334
protein phosphatase 1, regulatory subunit 15B
chr6_+_475264 1.88 ENSDART00000193615

chr15_+_29393519 1.84 ENSDART00000193488
ENSDART00000112375
glycerophosphodiester phosphodiesterase domain containing 5b
chr20_-_1268863 1.83 ENSDART00000109321
ENSDART00000027119
large tumor suppressor kinase 1
chr21_-_40557281 1.83 ENSDART00000172327
TAO kinase 1b
chr20_-_14781904 1.78 ENSDART00000187200
ENSDART00000179912
ENSDART00000160481
ENSDART00000026969
SUN domain containing ossification factor
chr1_-_45616242 1.77 ENSDART00000150066
activating transcription factor 7 interacting protein
chr7_+_1473929 1.76 ENSDART00000050687
lysophosphatidylcholine acyltransferase 4
chr7_-_48396193 1.71 ENSDART00000083555
SIN3 transcription regulator family member Ab
chr1_-_45616470 1.69 ENSDART00000150165
activating transcription factor 7 interacting protein
chr21_-_43398457 1.68 ENSDART00000166530
cyclin I family, member 2
chr20_+_46741074 1.65 ENSDART00000145294
si:ch211-57i17.1
chr11_-_35975026 1.62 ENSDART00000186219
inositol 1,4,5-trisphosphate receptor, type 1b
chr8_+_23165749 1.58 ENSDART00000063057
DnaJ (Hsp40) homolog, subfamily C, member 5aa
chr10_+_39199547 1.57 ENSDART00000075943
etoposide induced 2.4
chr21_+_21279159 1.57 ENSDART00000148346
inositol-trisphosphate 3-kinase Ca
chr16_-_2870522 1.57 ENSDART00000148543
CUB domain containing protein 1a
chr2_+_25657958 1.54 ENSDART00000161407
TRAF2 and NCK interacting kinase a
chr20_-_16156419 1.53 ENSDART00000037420
Ral GEF with PH domain and SH3 binding motif 2
chr15_-_9421481 1.52 ENSDART00000189045
ENSDART00000177158
sacsin molecular chaperone
chr22_+_31025096 1.51 ENSDART00000185953
zmp:0000000735
chr8_+_2656231 1.51 ENSDART00000160833
family with sequence similarity 102, member Aa
chr2_+_25658112 1.51 ENSDART00000051234
TRAF2 and NCK interacting kinase a
chr7_+_38962207 1.50 ENSDART00000173565
diacylglycerol kinase, zeta a
chr19_+_13994563 1.49 ENSDART00000164696
transmembrane protein 222b
chr16_-_1757521 1.47 ENSDART00000124660
activating signal cointegrator 1 complex subunit 3
chr13_+_23093743 1.47 ENSDART00000148034
phosphoinositide-3-kinase adaptor protein 1
chr6_+_41503854 1.46 ENSDART00000136538
ENSDART00000140108
ENSDART00000084861
cytokine inducible SH2-containing protein
chr22_+_883678 1.44 ENSDART00000140588
serine/threonine kinase 38b
chr21_-_11054605 1.43 ENSDART00000191378
ENSDART00000084061
neural precursor cell expressed, developmentally down-regulated 4-like
chr13_+_16521898 1.43 ENSDART00000122557
potassium large conductance calcium-activated channel, subfamily M, alpha member 1a
chr22_-_16275236 1.41 ENSDART00000149051
cell division cycle 14Ab
chr24_-_28381404 1.40 ENSDART00000148406
protein kinase, AMP-activated, gamma 2 non-catalytic subunit a
chr10_+_15603082 1.40 ENSDART00000024450
zinc finger, AN1-type domain 5b
chr11_+_19370717 1.38 ENSDART00000165906
prickle homolog 2b
chr19_-_26769867 1.37 ENSDART00000043776
ENSDART00000159489
ENSDART00000138675
proline-rich coiled-coil 2A
chr8_-_5847533 1.37 ENSDART00000192489

chr2_-_58075414 1.37 ENSDART00000161920
nectin cell adhesion molecule 4
chr15_-_25094026 1.35 ENSDART00000129154
exonuclease 5
chr16_-_5844881 1.34 ENSDART00000085678
trafficking protein, kinesin binding 1a
chr21_-_43398122 1.34 ENSDART00000050533
cyclin I family, member 2
chr18_-_26715156 1.33 ENSDART00000142043
MALT paracaspase 3
chr9_+_55536005 1.33 ENSDART00000192364
matrix-remodelling associated 5b
chr3_+_35812040 1.33 ENSDART00000075903
ENSDART00000147712
cytokine receptor-like factor 3
chr3_+_16841942 1.32 ENSDART00000023985
ENSDART00000145317
serine/threonine kinase 17a like
chr6_+_3334392 1.32 ENSDART00000133707
ENSDART00000130879
ST3 beta-galactoside alpha-2,3-sialyltransferase 3a
chr25_+_3104959 1.32 ENSDART00000167130
RAB3A interacting protein (rabin3)-like 1
chr24_+_10039165 1.30 ENSDART00000144186
POU class 6 homeobox 2
chr15_-_25209308 1.30 ENSDART00000157857
MAX network transcriptional repressor a
chr8_+_8166285 1.29 ENSDART00000147940
plexin B3
chr17_-_40956035 1.27 ENSDART00000124715
si:dkey-16j16.4
chr21_+_43253538 1.27 ENSDART00000179940
ENSDART00000164806
ENSDART00000147026
shroom family member 1
chr12_-_9132682 1.25 ENSDART00000066471
ADAM metallopeptidase domain 8b
chr21_-_11054876 1.25 ENSDART00000146576
neural precursor cell expressed, developmentally down-regulated 4-like
chr15_-_25093680 1.24 ENSDART00000062695
exonuclease 5
chr2_-_24061575 1.24 ENSDART00000089234
solute carrier family 12 (potassium/chloride transporter), member 7a
chr11_-_16395956 1.21 ENSDART00000115085
leucine-rich repeats and immunoglobulin-like domains 1
chr11_+_19370447 1.21 ENSDART00000186154
prickle homolog 2b
chr5_+_61361815 1.21 ENSDART00000009507
GATS protein-like 2
chr8_-_22739757 1.19 ENSDART00000182167
ENSDART00000171891
IQ motif and Sec7 domain 2a
chr19_+_4892281 1.18 ENSDART00000150969
cyclin-dependent kinase 12
chr3_-_16227490 1.14 ENSDART00000057159
ENSDART00000130611
ENSDART00000012835
calcium channel, voltage-dependent, beta 1 subunit
chr10_+_39200213 1.12 ENSDART00000153727
etoposide induced 2.4
chr19_-_46088429 1.11 ENSDART00000161385
phosphatidylserine synthase 1b
chr19_-_26770083 1.11 ENSDART00000193811
ENSDART00000174455
proline-rich coiled-coil 2A
chr7_+_55112922 1.10 ENSDART00000073549
snail family zinc finger 3
chr18_-_2727764 1.10 ENSDART00000160841
si:ch211-248g20.5
chr12_+_23850661 1.10 ENSDART00000152921
supervillin a
chr9_+_23825440 1.08 ENSDART00000138470
integrator complex subunit 6
chr11_-_44030962 1.08 ENSDART00000171910

chr15_+_47618221 1.07 ENSDART00000168722
PAF1 homolog, Paf1/RNA polymerase II complex component
chr25_+_16356083 1.07 ENSDART00000125925
ENSDART00000125444
TEA domain family member 1a
chr22_+_28236737 1.06 ENSDART00000086868
SUMO1/sentrin specific peptidase 7b
chr20_+_9474841 1.06 ENSDART00000053847
RAD51 paralog B
chr16_+_7991274 1.05 ENSDART00000179704
anoctamin 10a
chr8_+_39802506 1.05 ENSDART00000018862
HNF1 homeobox a
chr19_+_935565 1.02 ENSDART00000113368
ring finger protein 5
chr24_-_10828560 1.01 ENSDART00000132282
family with sequence similarity 49, member Bb
chr9_-_53899106 1.01 ENSDART00000171986
component of oligomeric golgi complex 3
chr25_-_6389713 1.01 ENSDART00000083539
SIN3 transcription regulator family member Aa
chr10_+_37500234 0.99 ENSDART00000132096
ENSDART00000099473
musashi RNA-binding protein 2a
chr13_-_26799244 0.99 ENSDART00000036419
vaccinia related kinase 2
chr19_+_390298 0.98 ENSDART00000136361
sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6D
chr17_+_44756247 0.97 ENSDART00000153773
CLOCK-interacting pacemaker a
chr6_-_60104628 0.96 ENSDART00000057463
ENSDART00000169188
prostate transmembrane protein, androgen induced 1
chr14_+_30910114 0.95 ENSDART00000187166
ENSDART00000078187
forkhead box O4
chr2_+_44666705 0.95 ENSDART00000139137
YEATS domain containing 2
chr20_+_812012 0.94 ENSDART00000179299
ENSDART00000137135
meiosis-specific, MEI4 homolog (S. cerevisiae)
chr20_+_36820965 0.94 ENSDART00000153085
ENSDART00000062935
hdc homolog, cell cycle regulator
chr14_+_28545198 0.94 ENSDART00000125362
ENSDART00000105902
hyaluronan-mediated motility receptor (RHAMM)
chr25_+_3507368 0.94 ENSDART00000157777
zgc:153293
chr1_-_55210619 0.92 ENSDART00000111671
methylthioribose-1-phosphate isomerase 1
chr13_-_18069421 0.91 ENSDART00000146772
ENSDART00000134477
zinc finger, AN1-type domain 4
chr2_+_105748 0.91 ENSDART00000169601

chr22_+_12366516 0.90 ENSDART00000157802
R3H domain containing 1
chr5_+_72152813 0.90 ENSDART00000149910
c-abl oncogene 1, non-receptor tyrosine kinase
chr11_-_40504170 0.88 ENSDART00000165394
si:dkeyp-61b2.1
chr2_+_16696052 0.88 ENSDART00000022356
ENSDART00000164329
protein phosphatase 1, regulatory (inhibitor) subunit 7
chr12_-_17492852 0.87 ENSDART00000012421
ENSDART00000138766
ENSDART00000130735
multiple inositol-polyphosphate phosphatase 1b
chr20_-_28931901 0.87 ENSDART00000153082
ENSDART00000046042
sushi domain containing 6
chr2_+_24867534 0.86 ENSDART00000158050
RAB3A, member RAS oncogene family, a
chr9_-_704667 0.86 ENSDART00000147092
CASP8 and FADD-like apoptosis regulator b
chr3_-_33941875 0.85 ENSDART00000047660
general transcription factor IIF, polypeptide 1
chr15_+_3125136 0.84 ENSDART00000130968
regulator of chromosome condensation (RCC1) and BTB (POZ) domain containing protein 2
chr6_+_3334710 0.82 ENSDART00000132848
ST3 beta-galactoside alpha-2,3-sialyltransferase 3a
chr14_-_15154695 0.82 ENSDART00000160677
UV-stimulated scaffold protein A
chr19_-_31900893 0.82 ENSDART00000113797
zinc finger and BTB domain containing 10
chr15_-_43768776 0.80 ENSDART00000170398
glutamate receptor, metabotropic 5b
chr14_-_46113321 0.80 ENSDART00000169040
ENSDART00000161475
ENSDART00000124925
si:ch211-235e9.8
chr16_-_17586883 0.80 ENSDART00000017142
mannose-6-phosphate receptor (cation dependent)
chr1_-_59232267 0.80 ENSDART00000169658
ENSDART00000163257
A kinase (PRKA) anchor protein 8-like
chr3_+_14499075 0.80 ENSDART00000162853
ENSDART00000167776
ENSDART00000162932
ENSDART00000168229
transmembrane protein 205
chr21_-_13972745 0.79 ENSDART00000143874
AT-hook transcription factor
chr7_+_38962459 0.79 ENSDART00000173851
diacylglycerol kinase, zeta a
chr17_+_51746830 0.79 ENSDART00000184230
ornithine decarboxylase 1
chr22_-_5918670 0.78 ENSDART00000141373
si:rp71-36a1.1
chr23_-_30960506 0.78 ENSDART00000142661
oxysterol binding protein-like 2a
chr17_+_21546993 0.77 ENSDART00000182387
carbohydrate (N-acetylgalactosamine 4-sulfate 6-O) sulfotransferase 15
chr19_+_1097393 0.77 ENSDART00000168218

chr10_-_42297889 0.77 ENSDART00000099262
transcription factor 7 like 1a
chr19_+_6990970 0.76 ENSDART00000158758
ENSDART00000160482
ENSDART00000193566
kinesin family member C1
chr9_-_52920305 0.76 ENSDART00000166906
transient receptor potential cation channel, subfamily M, member 2
chr7_+_22792132 0.75 ENSDART00000135207
ENSDART00000146801
RNA binding motif protein 4.3
chr25_+_4635355 0.72 ENSDART00000021120
protein-glucosylgalactosylhydroxylysine glucosidase
chr7_-_16598212 0.72 ENSDART00000128488
E2F transcription factor 8
chr5_-_13086616 0.72 ENSDART00000051664
yippee-like 1
chr23_+_41200854 0.72 ENSDART00000109567
Nance-Horan syndrome a (congenital cataracts and dental anomalies)
chr15_-_25435085 0.71 ENSDART00000112079
TLC domain containing 2
chr22_-_26558166 0.71 ENSDART00000111125
GLIS family zinc finger 2a
chr4_-_5795309 0.71 ENSDART00000039987
phosphoglucomutase 3
chr1_-_12393060 0.68 ENSDART00000079782
sodium channel and clathrin linker 1
chr1_-_55196103 0.68 ENSDART00000140153
methylthioribose-1-phosphate isomerase 1
chr17_-_23709347 0.68 ENSDART00000124661
3'-phosphoadenosine 5'-phosphosulfate synthase 2a
chr7_-_6444011 0.68 ENSDART00000173010
zgc:112234
chr12_-_14211293 0.67 ENSDART00000158399
AVL9 homolog (S. cerevisiase)
chr14_+_1719367 0.65 ENSDART00000157696
transient receptor potential cation channel, subfamily C, member 7b
chr3_-_36440705 0.65 ENSDART00000162875
rogdi homolog (Drosophila)
chr7_+_13988075 0.64 ENSDART00000186812
furin (paired basic amino acid cleaving enzyme) a
chr15_-_47956388 0.63 ENSDART00000116506
si:ch1073-111c8.3
chr3_-_33941319 0.63 ENSDART00000026090
ENSDART00000111878
general transcription factor IIF, polypeptide 1
chr9_+_13714379 0.62 ENSDART00000017593
ENSDART00000145503
transmembrane protein 237a
chr17_-_48944465 0.62 ENSDART00000154110
si:ch1073-80i24.3
chr7_-_6429031 0.62 ENSDART00000173413
zgc:112234
chr14_-_32503363 0.62 ENSDART00000034883
MCF.2 cell line derived transforming sequence a
chr12_+_14149686 0.61 ENSDART00000123741
kelch repeat and BTB (POZ) domain containing 2
chr12_-_37449396 0.60 ENSDART00000152951
CDC42 effector protein (Rho GTPase binding) 4b
chr5_+_20319519 0.59 ENSDART00000004217
coronin, actin binding protein, 1Ca
chr23_-_18982499 0.59 ENSDART00000012507
bcl2-like 1
chr2_+_24868010 0.59 ENSDART00000078838
RAB3A, member RAS oncogene family, a
chr19_+_12406583 0.56 ENSDART00000013865
ENSDART00000151535
SEH1-like (S. cerevisiae)
chr13_-_45022527 0.56 ENSDART00000159021
KH domain containing, RNA binding, signal transduction associated 1a
chr3_+_11548516 0.56 ENSDART00000059117
monocyte to macrophage differentiation-associated
chr24_+_42132962 0.56 ENSDART00000187739
WW domain containing E3 ubiquitin protein ligase 1
chr6_+_2271559 0.55 ENSDART00000165223
pre-B-cell leukemia homeobox 1b
chr19_-_2707048 0.54 ENSDART00000166112
interleukin 6 (interferon, beta 2)
chr22_+_94692 0.53 ENSDART00000114777
NCK interacting protein with SH3 domain
chr17_+_27723490 0.53 ENSDART00000123588
ENSDART00000170462
ENSDART00000169708
QKI, KH domain containing, RNA binding a
chr18_-_22094102 0.51 ENSDART00000100904
par-6 family cell polarity regulator alpha
chr20_-_51727860 0.51 ENSDART00000147044
BRO1 domain and CAAX motif containing
chr1_+_604127 0.51 ENSDART00000133165
junctional adhesion molecule 2a

Network of associatons between targets according to the STRING database.

First level regulatory network of sp2

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
1.9 5.8 GO:0010961 cellular magnesium ion homeostasis(GO:0010961)
0.9 15.5 GO:0060046 binding of sperm to zona pellucida(GO:0007339) egg coat formation(GO:0035803) regulation of acrosome reaction(GO:0060046) positive regulation of acrosome reaction(GO:2000344)
0.8 3.0 GO:0002495 antigen processing and presentation of peptide antigen via MHC class II(GO:0002495)
0.7 2.1 GO:0035477 regulation of angioblast cell migration involved in selective angioblast sprouting(GO:0035477)
0.6 2.5 GO:0090244 endodermal digestive tract morphogenesis(GO:0061031) Wnt signaling pathway involved in somitogenesis(GO:0090244) negative regulation of canonical Wnt signaling pathway involved in heart development(GO:1905067)
0.6 3.0 GO:0006700 C21-steroid hormone biosynthetic process(GO:0006700)
0.5 1.6 GO:0019284 L-methionine biosynthetic process from S-adenosylmethionine(GO:0019284)
0.5 1.4 GO:0031630 regulation of synaptic vesicle fusion to presynaptic membrane(GO:0031630)
0.5 4.1 GO:0016121 carotene metabolic process(GO:0016119) carotene catabolic process(GO:0016121) terpene metabolic process(GO:0042214) terpene catabolic process(GO:0046247)
0.4 2.1 GO:0010586 miRNA metabolic process(GO:0010586)
0.4 1.2 GO:0051044 positive regulation of membrane protein ectodomain proteolysis(GO:0051044)
0.3 2.7 GO:0033206 meiotic cytokinesis(GO:0033206) polar body extrusion after meiotic divisions(GO:0040038)
0.3 2.7 GO:2000650 negative regulation of sodium ion transmembrane transporter activity(GO:2000650)
0.3 1.5 GO:0045647 negative regulation of erythrocyte differentiation(GO:0045647)
0.3 1.2 GO:0042754 negative regulation of circadian rhythm(GO:0042754)
0.3 0.8 GO:0099553 trans-synaptic signaling by lipid, modulating synaptic transmission(GO:0099552) trans-synaptic signaling by endocannabinoid, modulating synaptic transmission(GO:0099553)
0.3 2.1 GO:0032515 negative regulation of phosphoprotein phosphatase activity(GO:0032515)
0.3 3.5 GO:0090309 methylation-dependent chromatin silencing(GO:0006346) positive regulation of chromatin silencing(GO:0031937) regulation of methylation-dependent chromatin silencing(GO:0090308) positive regulation of methylation-dependent chromatin silencing(GO:0090309)
0.2 2.2 GO:2000251 positive regulation of actin cytoskeleton reorganization(GO:2000251)
0.2 2.1 GO:0046716 muscle cell cellular homeostasis(GO:0046716)
0.2 0.7 GO:0034035 sulfate assimilation(GO:0000103) purine ribonucleoside bisphosphate metabolic process(GO:0034035) purine ribonucleoside bisphosphate biosynthetic process(GO:0034036) 3'-phosphoadenosine 5'-phosphosulfate metabolic process(GO:0050427) 3'-phosphoadenosine 5'-phosphosulfate biosynthetic process(GO:0050428)
0.2 1.3 GO:0098957 anterograde axonal transport of mitochondrion(GO:0098957)
0.2 0.8 GO:0060829 negative regulation of canonical Wnt signaling pathway involved in neural plate anterior/posterior pattern formation(GO:0060829)
0.2 1.5 GO:0006307 DNA dealkylation involved in DNA repair(GO:0006307)
0.2 0.7 GO:0033301 cell cycle comprising mitosis without cytokinesis(GO:0033301)
0.2 0.7 GO:0055091 phospholipid homeostasis(GO:0055091)
0.2 1.8 GO:0046850 regulation of bone remodeling(GO:0046850)
0.2 3.7 GO:0032968 positive regulation of transcription elongation from RNA polymerase II promoter(GO:0032968)
0.2 1.9 GO:0035307 positive regulation of dephosphorylation(GO:0035306) positive regulation of protein dephosphorylation(GO:0035307)
0.2 1.8 GO:0003139 secondary heart field specification(GO:0003139) regulation of organ growth(GO:0046620)
0.1 2.9 GO:0001539 cilium or flagellum-dependent cell motility(GO:0001539) cilium-dependent cell motility(GO:0060285)
0.1 1.4 GO:0071850 mitotic cell cycle arrest(GO:0071850)
0.1 1.0 GO:0060394 negative regulation of pathway-restricted SMAD protein phosphorylation(GO:0060394)
0.1 0.9 GO:0042138 meiotic DNA double-strand break formation(GO:0042138)
0.1 0.8 GO:0006283 transcription-coupled nucleotide-excision repair(GO:0006283)
0.1 0.3 GO:0045724 positive regulation of cilium assembly(GO:0045724)
0.1 1.1 GO:0006659 phosphatidylserine biosynthetic process(GO:0006659)
0.1 1.4 GO:0010996 response to auditory stimulus(GO:0010996)
0.1 0.3 GO:0039535 RIG-I signaling pathway(GO:0039529) regulation of viral-induced cytoplasmic pattern recognition receptor signaling pathway(GO:0039531) regulation of RIG-I signaling pathway(GO:0039535)
0.1 2.3 GO:0007205 protein kinase C-activating G-protein coupled receptor signaling pathway(GO:0007205)
0.1 0.3 GO:0019264 glycine biosynthetic process from serine(GO:0019264)
0.1 0.5 GO:0031293 membrane protein intracellular domain proteolysis(GO:0031293)
0.1 0.6 GO:0003272 endocardial cushion formation(GO:0003272)
0.1 0.5 GO:0006953 acute-phase response(GO:0006953)
0.1 0.8 GO:0033387 putrescine biosynthetic process from ornithine(GO:0033387)
0.1 1.6 GO:0032958 inositol phosphate biosynthetic process(GO:0032958)
0.1 3.3 GO:1901385 regulation of voltage-gated calcium channel activity(GO:1901385)
0.1 0.3 GO:0006272 leading strand elongation(GO:0006272) nucleotide-excision repair, DNA gap filling(GO:0006297)
0.1 0.8 GO:0006622 protein targeting to lysosome(GO:0006622)
0.1 0.6 GO:0006477 protein sulfation(GO:0006477) peptidyl-tyrosine sulfation(GO:0006478)
0.1 3.0 GO:0032402 melanosome transport(GO:0032402) pigment granule transport(GO:0051904)
0.1 2.6 GO:0036297 interstrand cross-link repair(GO:0036297)
0.1 0.5 GO:0033169 histone H3-K9 demethylation(GO:0033169)
0.1 0.4 GO:0030422 production of siRNA involved in RNA interference(GO:0030422)
0.1 0.6 GO:0043154 negative regulation of cysteine-type endopeptidase activity involved in apoptotic process(GO:0043154)
0.1 0.8 GO:0008089 anterograde axonal transport(GO:0008089)
0.1 0.4 GO:0051561 positive regulation of mitochondrial calcium ion concentration(GO:0051561)
0.1 1.1 GO:0016926 protein desumoylation(GO:0016926)
0.1 0.2 GO:0021785 branchiomotor neuron axon guidance(GO:0021785)
0.1 0.5 GO:0070935 3'-UTR-mediated mRNA stabilization(GO:0070935)
0.1 0.4 GO:0097107 postsynaptic density assembly(GO:0097107) modulation of excitatory postsynaptic potential(GO:0098815) positive regulation of excitatory postsynaptic potential(GO:2000463)
0.1 0.6 GO:0051315 attachment of mitotic spindle microtubules to kinetochore(GO:0051315)
0.1 1.3 GO:1902285 semaphorin-plexin signaling pathway involved in neuron projection guidance(GO:1902285) semaphorin-plexin signaling pathway involved in axon guidance(GO:1902287)
0.1 1.8 GO:0097194 execution phase of apoptosis(GO:0097194)
0.0 0.7 GO:0045162 clustering of voltage-gated sodium channels(GO:0045162)
0.0 2.7 GO:0016575 histone deacetylation(GO:0016575)
0.0 1.2 GO:0006884 cell volume homeostasis(GO:0006884)
0.0 0.6 GO:0060971 embryonic heart tube left/right pattern formation(GO:0060971)
0.0 0.5 GO:0061026 cardiac muscle tissue regeneration(GO:0061026)
0.0 1.1 GO:0034472 snRNA 3'-end processing(GO:0034472)
0.0 1.8 GO:0007019 microtubule depolymerization(GO:0007019)
0.0 0.8 GO:0051289 protein homotetramerization(GO:0051289)
0.0 0.2 GO:0071260 cellular response to mechanical stimulus(GO:0071260)
0.0 1.0 GO:0003323 type B pancreatic cell development(GO:0003323)
0.0 0.1 GO:0009312 oligosaccharide biosynthetic process(GO:0009312)
0.0 1.1 GO:0051014 actin filament severing(GO:0051014)
0.0 2.1 GO:0051091 positive regulation of sequence-specific DNA binding transcription factor activity(GO:0051091)
0.0 1.0 GO:1903039 positive regulation of homotypic cell-cell adhesion(GO:0034112) positive regulation of T cell activation(GO:0050870) positive regulation of leukocyte cell-cell adhesion(GO:1903039)
0.0 0.9 GO:0051209 release of sequestered calcium ion into cytosol(GO:0051209)
0.0 1.4 GO:0003401 axis elongation(GO:0003401)
0.0 0.4 GO:0042026 protein refolding(GO:0042026)
0.0 1.0 GO:0006891 intra-Golgi vesicle-mediated transport(GO:0006891)
0.0 3.7 GO:0060027 convergent extension involved in gastrulation(GO:0060027)
0.0 2.8 GO:0030178 negative regulation of Wnt signaling pathway(GO:0030178)
0.0 0.8 GO:0019319 hexose biosynthetic process(GO:0019319)
0.0 0.1 GO:0006046 N-acetylglucosamine catabolic process(GO:0006046)
0.0 2.3 GO:0008543 fibroblast growth factor receptor signaling pathway(GO:0008543)
0.0 0.4 GO:0007530 sex determination(GO:0007530)
0.0 0.2 GO:0006895 Golgi to endosome transport(GO:0006895)
0.0 0.7 GO:0006828 manganese ion transport(GO:0006828)
0.0 0.1 GO:0008206 bile acid biosynthetic process(GO:0006699) bile acid metabolic process(GO:0008206)
0.0 0.6 GO:0090148 membrane fission(GO:0090148)
0.0 0.9 GO:0032011 ARF protein signal transduction(GO:0032011) regulation of ARF protein signal transduction(GO:0032012)
0.0 0.5 GO:0007520 myoblast fusion(GO:0007520)
0.0 0.2 GO:1900407 regulation of cellular response to oxidative stress(GO:1900407)
0.0 0.2 GO:0019682 pentose-phosphate shunt(GO:0006098) glyceraldehyde-3-phosphate metabolic process(GO:0019682)
0.0 0.8 GO:1902850 mitotic spindle assembly(GO:0090307) microtubule cytoskeleton organization involved in mitosis(GO:1902850)
0.0 0.9 GO:0000079 regulation of cyclin-dependent protein serine/threonine kinase activity(GO:0000079) regulation of cyclin-dependent protein kinase activity(GO:1904029)
0.0 0.1 GO:0032475 otolith formation(GO:0032475)
0.0 0.6 GO:0000289 nuclear-transcribed mRNA poly(A) tail shortening(GO:0000289)
0.0 2.3 GO:0021782 glial cell development(GO:0021782)
0.0 0.5 GO:0003351 epithelial cilium movement(GO:0003351)
0.0 2.6 GO:0006898 receptor-mediated endocytosis(GO:0006898)
0.0 0.1 GO:0044458 motile cilium assembly(GO:0044458)
0.0 0.0 GO:0006295 nucleotide-excision repair, DNA incision, 3'-to lesion(GO:0006295)
0.0 0.4 GO:0035338 long-chain fatty-acyl-CoA biosynthetic process(GO:0035338)
0.0 1.7 GO:0016236 macroautophagy(GO:0016236)
0.0 0.0 GO:0060039 pericardium development(GO:0060039) visceral serous pericardium development(GO:0061032)
0.0 0.2 GO:0071577 zinc II ion transmembrane transport(GO:0071577)
0.0 0.9 GO:0045732 positive regulation of protein catabolic process(GO:0045732)
0.0 0.4 GO:0042149 cellular response to glucose starvation(GO:0042149)
0.0 1.5 GO:0046578 regulation of Ras protein signal transduction(GO:0046578)
0.0 0.5 GO:0001841 neural tube formation(GO:0001841)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 2.0 GO:0061673 mitotic spindle astral microtubule(GO:0061673)
0.4 1.2 GO:0071065 alpha9-beta1 integrin-vascular cell adhesion molecule-1 complex(GO:0071065)
0.4 2.5 GO:0030877 beta-catenin destruction complex(GO:0030877)
0.3 1.3 GO:0070319 Golgi to plasma membrane transport vesicle(GO:0070319)
0.3 1.1 GO:0035327 transcriptionally active chromatin(GO:0035327)
0.2 1.4 GO:1902636 kinociliary basal body(GO:1902636)
0.2 2.7 GO:0016580 Sin3 complex(GO:0016580)
0.2 1.1 GO:0033063 Rad51B-Rad51C-Rad51D-XRCC2 complex(GO:0033063)
0.2 1.5 GO:0005674 transcription factor TFIIF complex(GO:0005674)
0.2 0.7 GO:0043291 RAVE complex(GO:0043291)
0.2 2.1 GO:0000940 condensed chromosome outer kinetochore(GO:0000940)
0.1 0.4 GO:0034663 endoplasmic reticulum chaperone complex(GO:0034663)
0.1 1.2 GO:0019908 cyclin/CDK positive transcription elongation factor complex(GO:0008024) nuclear cyclin-dependent protein kinase holoenzyme complex(GO:0019908)
0.1 0.5 GO:0098553 integral component of cytoplasmic side of endoplasmic reticulum membrane(GO:0071458) integral component of lumenal side of endoplasmic reticulum membrane(GO:0071556) lumenal side of endoplasmic reticulum membrane(GO:0098553)
0.1 1.4 GO:0031588 nucleotide-activated protein kinase complex(GO:0031588)
0.1 1.9 GO:0000164 protein phosphatase type 1 complex(GO:0000164)
0.1 0.3 GO:0008622 epsilon DNA polymerase complex(GO:0008622)
0.1 1.0 GO:0017119 Golgi transport complex(GO:0017119)
0.1 1.6 GO:0030667 secretory granule membrane(GO:0030667)
0.1 1.3 GO:0002116 semaphorin receptor complex(GO:0002116)
0.1 4.0 GO:0031901 early endosome membrane(GO:0031901)
0.1 1.1 GO:0032039 integrator complex(GO:0032039)
0.1 0.6 GO:0031080 nuclear pore outer ring(GO:0031080)
0.0 3.3 GO:0005891 voltage-gated calcium channel complex(GO:0005891)
0.0 0.3 GO:0032783 ELL-EAF complex(GO:0032783)
0.0 0.9 GO:0000795 synaptonemal complex(GO:0000795)
0.0 2.2 GO:0030175 filopodium(GO:0030175)
0.0 0.8 GO:1990907 beta-catenin-TCF complex(GO:1990907)
0.0 5.2 GO:0043296 apical junction complex(GO:0043296)
0.0 1.0 GO:0005844 polysome(GO:0005844)
0.0 2.7 GO:0000932 cytoplasmic mRNA processing body(GO:0000932)
0.0 11.7 GO:0031012 extracellular matrix(GO:0031012)
0.0 1.5 GO:0005942 phosphatidylinositol 3-kinase complex(GO:0005942)
0.0 0.9 GO:0000307 cyclin-dependent protein kinase holoenzyme complex(GO:0000307)
0.0 0.6 GO:0035869 ciliary transition zone(GO:0035869)
0.0 0.4 GO:0090665 dystrophin-associated glycoprotein complex(GO:0016010) glycoprotein complex(GO:0090665)
0.0 1.3 GO:0030173 integral component of Golgi membrane(GO:0030173) intrinsic component of Golgi membrane(GO:0031228)
0.0 0.8 GO:0099634 postsynaptic density membrane(GO:0098839) postsynaptic specialization membrane(GO:0099634)
0.0 0.6 GO:0032587 ruffle membrane(GO:0032587)
0.0 0.2 GO:0061617 MICOS complex(GO:0061617)
0.0 0.8 GO:0072686 mitotic spindle(GO:0072686)
0.0 2.7 GO:0030659 cytoplasmic vesicle membrane(GO:0030659)
0.0 0.4 GO:0042470 melanosome(GO:0042470) pigment granule(GO:0048770)
0.0 2.2 GO:0045211 postsynaptic membrane(GO:0045211)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
1.4 15.5 GO:0035804 structural constituent of egg coat(GO:0035804)
1.0 3.0 GO:0016713 cholesterol monooxygenase (side-chain-cleaving) activity(GO:0008386) oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced iron-sulfur protein as one donor, and incorporation of one atom of oxygen(GO:0016713)
0.9 2.6 GO:0045145 single-stranded DNA 5'-3' exodeoxyribonuclease activity(GO:0045145)
0.5 6.5 GO:0047631 ADP-ribose diphosphatase activity(GO:0047631)
0.5 4.1 GO:0003834 beta-carotene 15,15'-monooxygenase activity(GO:0003834) carotenoid dioxygenase activity(GO:0010436)
0.4 1.5 GO:0001096 TFIIF-class transcription factor binding(GO:0001096)
0.3 2.7 GO:0019871 sodium channel inhibitor activity(GO:0019871)
0.3 2.1 GO:0008118 N-acetyllactosaminide alpha-2,3-sialyltransferase activity(GO:0008118)
0.2 0.7 GO:0004781 adenylylsulfate kinase activity(GO:0004020) sulfate adenylyltransferase activity(GO:0004779) sulfate adenylyltransferase (ATP) activity(GO:0004781)
0.2 0.9 GO:0034416 bisphosphoglycerate phosphatase activity(GO:0034416)
0.2 2.1 GO:0035198 miRNA binding(GO:0035198)
0.2 1.0 GO:0070412 R-SMAD binding(GO:0070412)
0.1 0.4 GO:0004345 glucose-6-phosphate dehydrogenase activity(GO:0004345)
0.1 2.2 GO:0008093 cytoskeletal adaptor activity(GO:0008093)
0.1 2.1 GO:0051721 protein phosphatase 2A binding(GO:0051721)
0.1 1.6 GO:0005220 inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity(GO:0005220)
0.1 1.1 GO:0070139 ubiquitin-like protein-specific endopeptidase activity(GO:0070137) SUMO-specific endopeptidase activity(GO:0070139)
0.1 0.5 GO:0042500 aspartic endopeptidase activity, intramembrane cleaving(GO:0042500)
0.1 1.2 GO:0030332 cyclin binding(GO:0030332)
0.1 0.5 GO:0035575 histone demethylase activity (H4-K20 specific)(GO:0035575)
0.1 0.8 GO:0099530 G-protein coupled receptor activity involved in regulation of postsynaptic membrane potential(GO:0099530)
0.1 1.6 GO:0016861 intramolecular oxidoreductase activity, interconverting aldoses and ketoses(GO:0016861)
0.1 1.5 GO:0036312 phosphatidylinositol 3-kinase regulatory subunit binding(GO:0036312)
0.1 0.3 GO:0070016 armadillo repeat domain binding(GO:0070016)
0.1 3.3 GO:0008331 high voltage-gated calcium channel activity(GO:0008331)
0.1 1.1 GO:0000400 four-way junction DNA binding(GO:0000400)
0.1 1.5 GO:0030544 Hsp70 protein binding(GO:0030544)
0.1 0.3 GO:0070905 glycine hydroxymethyltransferase activity(GO:0004372) serine binding(GO:0070905)
0.1 1.6 GO:0000828 inositol hexakisphosphate kinase activity(GO:0000828)
0.1 3.0 GO:0042287 MHC protein binding(GO:0042287)
0.1 2.3 GO:0004143 diacylglycerol kinase activity(GO:0004143)
0.1 0.7 GO:0001217 bacterial-type RNA polymerase transcription factor activity, sequence-specific DNA binding(GO:0001130) bacterial-type RNA polymerase transcriptional repressor activity, sequence-specific DNA binding(GO:0001217)
0.1 0.8 GO:0004586 ornithine decarboxylase activity(GO:0004586)
0.1 1.4 GO:0015269 calcium-activated potassium channel activity(GO:0015269)
0.1 1.9 GO:0000993 RNA polymerase II core binding(GO:0000993)
0.1 0.3 GO:0008310 single-stranded DNA 3'-5' exodeoxyribonuclease activity(GO:0008310)
0.1 0.6 GO:0008476 protein-tyrosine sulfotransferase activity(GO:0008476)
0.1 2.1 GO:0004435 phosphatidylinositol phospholipase C activity(GO:0004435) phospholipase C activity(GO:0004629)
0.1 1.3 GO:0050811 GABA receptor binding(GO:0050811)
0.1 3.3 GO:0008013 beta-catenin binding(GO:0008013)
0.1 0.4 GO:0030160 GKAP/Homer scaffold activity(GO:0030160)
0.1 1.5 GO:0043138 3'-5' DNA helicase activity(GO:0043138)
0.1 2.1 GO:0030374 ligand-dependent nuclear receptor transcription coactivator activity(GO:0030374)
0.1 0.8 GO:0005537 mannose binding(GO:0005537)
0.1 0.7 GO:0016868 intramolecular transferase activity, phosphotransferases(GO:0016868)
0.0 1.4 GO:0016208 AMP binding(GO:0016208)
0.0 1.2 GO:0015379 cation:chloride symporter activity(GO:0015377) potassium:chloride symporter activity(GO:0015379)
0.0 0.6 GO:0043028 cysteine-type endopeptidase inhibitor activity involved in apoptotic process(GO:0043027) cysteine-type endopeptidase regulator activity involved in apoptotic process(GO:0043028)
0.0 1.5 GO:0046935 1-phosphatidylinositol-3-kinase regulator activity(GO:0046935)
0.0 0.8 GO:0005080 protein kinase C binding(GO:0005080)
0.0 1.3 GO:0017154 semaphorin receptor activity(GO:0017154)
0.0 0.1 GO:1902945 metalloendopeptidase activity involved in amyloid precursor protein catabolic process(GO:1902945)
0.0 0.8 GO:0008143 poly(A) binding(GO:0008143)
0.0 0.5 GO:0001965 G-protein alpha-subunit binding(GO:0001965)
0.0 0.4 GO:0047676 arachidonate-CoA ligase activity(GO:0047676)
0.0 0.7 GO:0070679 inositol 1,4,5 trisphosphate binding(GO:0070679)
0.0 0.6 GO:0030371 translation repressor activity(GO:0030371)
0.0 0.7 GO:0015926 glucosidase activity(GO:0015926)
0.0 0.8 GO:0015248 sterol transporter activity(GO:0015248)
0.0 0.3 GO:0000774 adenyl-nucleotide exchange factor activity(GO:0000774)
0.0 0.9 GO:0008574 ATP-dependent microtubule motor activity, plus-end-directed(GO:0008574)
0.0 0.9 GO:0005540 hyaluronic acid binding(GO:0005540)
0.0 1.1 GO:0005546 phosphatidylinositol-4,5-bisphosphate binding(GO:0005546)
0.0 0.3 GO:0044183 protein binding involved in protein folding(GO:0044183)
0.0 3.2 GO:0003714 transcription corepressor activity(GO:0003714)
0.0 4.0 GO:0004725 protein tyrosine phosphatase activity(GO:0004725)
0.0 6.1 GO:0005085 guanyl-nucleotide exchange factor activity(GO:0005085)
0.0 0.3 GO:0097602 cullin family protein binding(GO:0097602)
0.0 0.9 GO:0016538 cyclin-dependent protein serine/threonine kinase regulator activity(GO:0016538)
0.0 0.4 GO:0004181 metallocarboxypeptidase activity(GO:0004181)
0.0 0.3 GO:0005003 ephrin receptor activity(GO:0005003)
0.0 0.8 GO:0004715 non-membrane spanning protein tyrosine kinase activity(GO:0004715)
0.0 9.7 GO:0004674 protein serine/threonine kinase activity(GO:0004674)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.5 ST INTERFERON GAMMA PATHWAY Interferon gamma pathway.
0.2 2.1 PID S1P S1P4 PATHWAY S1P4 pathway
0.1 2.5 PID WNT CANONICAL PATHWAY Canonical Wnt signaling pathway
0.1 0.6 SA PROGRAMMED CELL DEATH Programmed cell death, or apoptosis, eliminates damaged or unneeded cells.
0.1 0.5 ST STAT3 PATHWAY STAT3 Pathway
0.1 3.1 PID FOXO PATHWAY FoxO family signaling
0.1 4.1 PID TGFBR PATHWAY TGF-beta receptor signaling
0.0 1.0 PID PS1 PATHWAY Presenilin action in Notch and Wnt signaling
0.0 0.9 PID LIS1 PATHWAY Lissencephaly gene (LIS1) in neuronal migration and development
0.0 1.6 PID RHOA REG PATHWAY Regulation of RhoA activity
0.0 1.2 PID ERBB4 PATHWAY ErbB4 signaling events
0.0 2.0 NABA ECM AFFILIATED Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.0 0.8 PID BCR 5PATHWAY BCR signaling pathway
0.0 0.4 PID CERAMIDE PATHWAY Ceramide signaling pathway

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 2.1 REACTOME ROLE OF SECOND MESSENGERS IN NETRIN1 SIGNALING Genes involved in Role of second messengers in netrin-1 signaling
0.4 1.8 REACTOME ACYL CHAIN REMODELLING OF PS Genes involved in Acyl chain remodelling of PS
0.3 3.0 REACTOME ENDOGENOUS STEROLS Genes involved in Endogenous sterols
0.2 2.5 REACTOME CTNNB1 PHOSPHORYLATION CASCADE Genes involved in Beta-catenin phosphorylation cascade
0.2 2.4 REACTOME METABOLISM OF POLYAMINES Genes involved in Metabolism of polyamines
0.1 2.8 REACTOME KINESINS Genes involved in Kinesins
0.1 2.3 REACTOME OTHER SEMAPHORIN INTERACTIONS Genes involved in Other semaphorin interactions
0.1 1.5 REACTOME VIRAL MESSENGER RNA SYNTHESIS Genes involved in Viral Messenger RNA Synthesis
0.1 0.5 REACTOME TGF BETA RECEPTOR SIGNALING IN EMT EPITHELIAL TO MESENCHYMAL TRANSITION Genes involved in TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)
0.1 0.9 REACTOME HYALURONAN UPTAKE AND DEGRADATION Genes involved in Hyaluronan uptake and degradation
0.1 1.8 REACTOME SIGNALING BY HIPPO Genes involved in Signaling by Hippo
0.1 3.3 REACTOME NCAM1 INTERACTIONS Genes involved in NCAM1 interactions
0.1 0.6 REACTOME INFLAMMASOMES Genes involved in Inflammasomes
0.1 1.5 REACTOME GROWTH HORMONE RECEPTOR SIGNALING Genes involved in Growth hormone receptor signaling
0.1 0.5 REACTOME IL 6 SIGNALING Genes involved in Interleukin-6 signaling
0.1 1.0 REACTOME DOWNREGULATION OF TGF BETA RECEPTOR SIGNALING Genes involved in Downregulation of TGF-beta receptor signaling
0.1 0.8 REACTOME CHONDROITIN SULFATE BIOSYNTHESIS Genes involved in Chondroitin sulfate biosynthesis
0.1 1.0 REACTOME REGULATION OF GENE EXPRESSION IN BETA CELLS Genes involved in Regulation of gene expression in beta cells
0.0 0.4 REACTOME ACTIVATION OF CHAPERONE GENES BY ATF6 ALPHA Genes involved in Activation of Chaperone Genes by ATF6-alpha
0.0 1.5 REACTOME ANTIGEN ACTIVATES B CELL RECEPTOR LEADING TO GENERATION OF SECOND MESSENGERS Genes involved in Antigen Activates B Cell Receptor Leading to Generation of Second Messengers
0.0 1.6 REACTOME NRAGE SIGNALS DEATH THROUGH JNK Genes involved in NRAGE signals death through JNK
0.0 1.0 REACTOME PIP3 ACTIVATES AKT SIGNALING Genes involved in PIP3 activates AKT signaling
0.0 0.8 REACTOME LYSOSOME VESICLE BIOGENESIS Genes involved in Lysosome Vesicle Biogenesis
0.0 0.9 REACTOME SIGNALING BY ROBO RECEPTOR Genes involved in Signaling by Robo receptor
0.0 0.3 REACTOME NFKB ACTIVATION THROUGH FADD RIP1 PATHWAY MEDIATED BY CASPASE 8 AND10 Genes involved in NF-kB activation through FADD/RIP-1 pathway mediated by caspase-8 and -10
0.0 1.2 REACTOME SIGNALING BY EGFR IN CANCER Genes involved in Signaling by EGFR in Cancer
0.0 0.9 REACTOME SIGNALING BY ERBB4 Genes involved in Signaling by ERBB4
0.0 0.4 REACTOME INSULIN SYNTHESIS AND PROCESSING Genes involved in Insulin Synthesis and Processing
0.0 0.3 REACTOME REPAIR SYNTHESIS FOR GAP FILLING BY DNA POL IN TC NER Genes involved in Repair synthesis for gap-filling by DNA polymerase in TC-NER
0.0 0.2 REACTOME ZINC TRANSPORTERS Genes involved in Zinc transporters
0.0 0.6 REACTOME REGULATION OF GLUCOKINASE BY GLUCOKINASE REGULATORY PROTEIN Genes involved in Regulation of Glucokinase by Glucokinase Regulatory Protein
0.0 0.2 REACTOME METABOLISM OF PORPHYRINS Genes involved in Metabolism of porphyrins
0.0 0.1 REACTOME BASE FREE SUGAR PHOSPHATE REMOVAL VIA THE SINGLE NUCLEOTIDE REPLACEMENT PATHWAY Genes involved in Base-free sugar-phosphate removal via the single-nucleotide replacement pathway
0.0 0.6 REACTOME FACTORS INVOLVED IN MEGAKARYOCYTE DEVELOPMENT AND PLATELET PRODUCTION Genes involved in Factors involved in megakaryocyte development and platelet production