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PRJNA195909:zebrafish embryo and larva development

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Results for sox6

Z-value: 0.92

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Transcription factors associated with sox6

Gene Symbol Gene ID Gene Info
ENSDARG00000015536 SRY-box transcription factor 6

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
sox6dr11_v1_chr7_+_27250186_27250186-0.665.3e-02Click!

Activity profile of sox6 motif

Sorted Z-values of sox6 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr12_+_48340133 3.44 ENSDART00000152899
ENSDART00000153335
ENSDART00000054788
DNA-damage-inducible transcript 4
chr17_-_2578026 2.39 ENSDART00000065821
zona pellucida glycoprotein 3, tandem duplicate 2
chr17_-_2590222 1.91 ENSDART00000185711

chr12_-_33354409 1.90 ENSDART00000178515
solute carrier family 16 (monocarboxylate transporter), member 3
chr1_-_33645967 1.85 ENSDART00000192758
claudin g
chr17_-_2573021 1.66 ENSDART00000074181
zona pellucida glycoprotein 3, tandem duplicate 2
chr13_+_33368503 1.61 ENSDART00000139650
BRF1, RNA polymerase III transcription initiation factor a
chr19_-_27588842 1.42 ENSDART00000121643
si:dkeyp-46h3.2
chr17_+_24597001 1.34 ENSDART00000191834
rearranged L-myc fusion
chr20_+_35445462 1.30 ENSDART00000124497
tudor domain containing 6
chr10_+_15608326 1.30 ENSDART00000188770
zinc finger, AN1-type domain 5b
chr16_-_54919260 1.27 ENSDART00000156533
keratinocyte differentiation factor 1a
chr8_+_8671229 1.20 ENSDART00000131963
ubiquitin specific peptidase 11
chr15_+_12429206 1.15 ENSDART00000168997
transmembrane protease, serine 4a
chr24_-_24724233 1.10 ENSDART00000127044
ENSDART00000012399
armadillo repeat containing 1
chr8_+_42941555 1.08 ENSDART00000183206
solute carrier family 23 (ascorbic acid transporter), member 2
chr7_-_24520866 1.08 ENSDART00000077039
fatty acid amide hydrolase 2b
chr24_-_19719240 1.07 ENSDART00000135405
cysteine-serine-rich nuclear protein 1b
chr7_+_25103965 1.05 ENSDART00000192561
ENSDART00000173721
si:dkey-23i12.9
chr5_+_40835601 1.01 ENSDART00000147767
si:dkey-3h3.3
chr3_+_49074008 0.99 ENSDART00000168864
zgc:112146
chr2_+_27386617 0.97 ENSDART00000134976
si:ch73-382f3.1
chr2_+_32846602 0.96 ENSDART00000056649
transmembrane protein 53
chr5_-_28149767 0.95 ENSDART00000051515
zgc:110329
chr9_-_32142311 0.93 ENSDART00000142768
ankyrin repeat domain 44
chr22_-_10440688 0.91 ENSDART00000111962
nucleolar protein 8
chr19_+_4051695 0.89 ENSDART00000166368
bloodthirsty-related gene family, member 24
chr19_-_23249822 0.88 ENSDART00000140665
growth factor receptor-bound protein 10a
chr17_+_27158706 0.85 ENSDART00000151829
ribosomal protein S6 kinase a, polypeptide 1
chr8_-_49499457 0.84 ENSDART00000098326
opsin 7, group member d
chr6_-_11362871 0.83 ENSDART00000151125
pericentrin
chr3_+_53156813 0.82 ENSDART00000114343
bromodomain containing 4
chr24_-_21343982 0.81 ENSDART00000012653
spindle and centriole associated protein 1
chr13_-_20540790 0.80 ENSDART00000131467
si:ch1073-126c3.2
chr10_+_2842923 0.79 ENSDART00000181895
YKT6 v-SNARE homolog (S. cerevisiae)
chr13_+_42309688 0.79 ENSDART00000158367
insulin-degrading enzyme
chr6_-_41138854 0.78 ENSDART00000128723
ENSDART00000151055
ENSDART00000132484
solute carrier family 6 member 22, tandem duplicate 1
chr25_+_34862225 0.73 ENSDART00000149782
zgc:194879
chr8_+_26879358 0.71 ENSDART00000132485
ribosomal modification protein rimK-like family member A
chr7_-_33868903 0.70 ENSDART00000173500
ENSDART00000178746
uveal autoantigen with coiled-coil domains and ankyrin repeats b
chr25_+_33063762 0.69 ENSDART00000189974
talin 2b
chr1_-_354115 0.69 ENSDART00000141590
ENSDART00000098627
protein S
chr7_+_24520518 0.68 ENSDART00000173604
bloodthirsty-related gene family, member 9
chr6_-_7735153 0.67 ENSDART00000151545
solute carrier family 25, member 38b
chr5_-_38384289 0.66 ENSDART00000135260
misshapen-like kinase 1
chr14_+_26247319 0.65 ENSDART00000192793
coiled-coil domain containing 69
chr8_+_16990120 0.65 ENSDART00000018934
phosphodiesterase 4D, cAMP-specific
chr23_+_7710721 0.64 ENSDART00000186852
ENSDART00000161193
kinesin family member 3B
chr10_+_17371356 0.63 ENSDART00000122663
signal peptide peptidase 3
chr9_+_21793565 0.62 ENSDART00000134915
REV1, polymerase (DNA directed)
chr16_+_53387085 0.60 ENSDART00000154223
ENSDART00000101404
kinesin family member 13A
chr10_-_28028998 0.60 ENSDART00000023545
ENSDART00000143487
integrator complex subunit 2
chr13_+_46941930 0.59 ENSDART00000056962
F-box protein 5
chr7_-_53117131 0.59 ENSDART00000169211
ENSDART00000168890
ENSDART00000172179
ENSDART00000167882
cadherin 1, type 1, E-cadherin (epithelial)
chr6_+_58280936 0.57 ENSDART00000155244
Ral GTPase activating protein, beta subunit (non-catalytic)
chr7_-_6459481 0.57 ENSDART00000173158
zgc:112234
chr17_+_7534180 0.56 ENSDART00000187512
SNF2 histone linker PHD RING helicase
chr24_+_18714212 0.55 ENSDART00000171181
centrosome and spindle pole associated protein 1a
chr22_+_4442473 0.55 ENSDART00000170751
toll-like receptor adaptor molecule 1
chr2_+_23731194 0.55 ENSDART00000155747
solute carrier family 22 member 13a
chr19_+_40069524 0.53 ENSDART00000151365
ENSDART00000140926
zinc finger, MYM-type 4
chr13_-_33700461 0.52 ENSDART00000160520
MAD2L1 binding protein
chr21_-_9914745 0.52 ENSDART00000172124
Rho GTPase activating protein 24
chr9_+_3055566 0.52 ENSDART00000189906
ENSDART00000175891
ENSDART00000093021
protein phosphatase 1 regulatory subunit 9A-like A
chr1_+_41690402 0.52 ENSDART00000177298
F-box protein 41
chr3_+_29641181 0.51 ENSDART00000151517
eukaryotic translation initiation factor 3, subunit D
chr17_+_7534365 0.51 ENSDART00000157123
SNF2 histone linker PHD RING helicase
chr10_+_39200213 0.51 ENSDART00000153727
etoposide induced 2.4
chr8_+_17869225 0.51 ENSDART00000080079
solute carrier family 44, member 5b
chr25_+_25737386 0.51 ENSDART00000108476
leucine rich repeat containing 61
chr20_+_733510 0.50 ENSDART00000135066
ENSDART00000015558
ENSDART00000152782
myosin VIa
chr11_+_34523132 0.50 ENSDART00000192257
zinc finger, matrin-type 3
chr21_+_36396864 0.50 ENSDART00000137309
gem (nuclear organelle) associated protein 5
chr3_-_25054002 0.50 ENSDART00000086768
E1A binding protein p300 b
chr7_-_32895668 0.49 ENSDART00000141828
anoctamin 5b
chr15_+_19458982 0.49 ENSDART00000132665
zgc:77784
chr22_-_37565348 0.48 ENSDART00000149482
ENSDART00000104478
fragile X mental retardation, autosomal homolog 1
chr15_-_30853246 0.47 ENSDART00000112511
A kinase (PRKA) anchor protein 1b
chr3_+_26244353 0.47 ENSDART00000103733
ATPase family, AAA domain containing 5a
chr15_+_29727799 0.47 ENSDART00000182006
zgc:153372
chr14_-_31060082 0.46 ENSDART00000111601
ENSDART00000161113
muscleblind-like splicing regulator 3
chr5_+_18012154 0.46 ENSDART00000139431
ENSDART00000048859
activating signal cointegrator 1 complex subunit 2
chr6_-_25180438 0.46 ENSDART00000159696
leucine rich repeat containing 8 VRAC subunit Db
chr12_+_19320657 0.46 ENSDART00000100075
ENSDART00000066389
transmembrane protein 184ba
chr6_+_54888493 0.46 ENSDART00000113331
neuron navigator 1b
chr9_-_18743012 0.45 ENSDART00000131626
TSC22 domain family, member 1
chr20_-_40754794 0.45 ENSDART00000187251
connexin 32.3
chr12_-_7280551 0.45 ENSDART00000061633
zgc:171971
chr11_+_31324335 0.44 ENSDART00000088093
signal-induced proliferation-associated 1 like 2
chr5_-_11905920 0.44 ENSDART00000114378
F-box and WD repeat domain containing 8
chr5_+_31480342 0.43 ENSDART00000098197
si:dkey-220k22.1
chr9_+_50001746 0.43 ENSDART00000058892
solute carrier family 38, member 11
chr22_+_4443689 0.42 ENSDART00000185490
toll-like receptor adaptor molecule 1
chr9_-_18742704 0.42 ENSDART00000145401
TSC22 domain family, member 1
chr15_+_17441734 0.42 ENSDART00000153729
sorting nexin 19b
chr11_-_11890001 0.41 ENSDART00000081544
WAS/WASL interacting protein family, member 2a
chr9_+_21795917 0.40 ENSDART00000169069
REV1, polymerase (DNA directed)
chr20_+_31217495 0.40 ENSDART00000020252
protein disulfide isomerase family A, member 6
chr7_-_24995631 0.40 ENSDART00000173955
ENSDART00000173791
REST corepressor 2
chr10_+_5744941 0.39 ENSDART00000159769
ENSDART00000184734
peptidylglycine alpha-amidating monooxygenase
chr22_+_29113796 0.39 ENSDART00000150264
phospholipase A2, group VI (cytosolic, calcium-independent)
chr6_-_19351495 0.39 ENSDART00000164287
growth factor receptor-bound protein 2a
chr13_+_15933168 0.39 ENSDART00000131390
fidgetin-like 1
chr2_+_3472832 0.38 ENSDART00000115278
connexin 47.1
chr7_-_49646251 0.38 ENSDART00000193674
-Ha-ras Harvey rat sarcoma viral oncogene homolog b
chr23_-_33944597 0.37 ENSDART00000133223
si:dkey-190g6.2
chr14_-_33978117 0.36 ENSDART00000128515
forkhead box A sequence
chr3_+_15773991 0.36 ENSDART00000089923
zinc finger protein 652
chr9_-_23891102 0.36 ENSDART00000186799
ankyrin repeat and SOCS box containing 18
chr19_+_7424347 0.34 ENSDART00000004622
splicing factor 3b, subunit 4
chr17_-_31611692 0.34 ENSDART00000141480
si:dkey-170l10.1
chr1_-_20068155 0.34 ENSDART00000102993
methyltransferase like 14
chr14_+_51056605 0.34 ENSDART00000159639

chr25_+_2668892 0.33 ENSDART00000122929
Bardet-Biedl syndrome 4
chr23_-_25798099 0.32 ENSDART00000041833
fat storage-inducing transmembrane protein 2
chr14_-_33872092 0.32 ENSDART00000111903
si:ch73-335m24.2
chr19_+_16068445 0.31 ENSDART00000138709
glucocorticoid modulatory element binding protein 1
chr11_+_24820542 0.31 ENSDART00000135443
lysine (K)-specific demethylase 5Ba
chr2_+_26240631 0.30 ENSDART00000129895
paralemmin 1b
chr7_-_40144686 0.30 ENSDART00000109166
WD repeat domain 60
chr10_+_3428194 0.29 ENSDART00000081599
protein tyrosine phosphatase, non-receptor type 11, a
chr25_+_28567381 0.29 ENSDART00000126552
si:ch211-190o6.3
chr2_+_29257942 0.29 ENSDART00000184362
ENSDART00000025562
cadherin 18, type 2a
chr2_+_49457626 0.29 ENSDART00000129967
SH3-domain GRB2-like 1a
chr16_+_24978203 0.29 ENSDART00000156579
si:dkeyp-84f3.5
chr5_-_66160415 0.28 ENSDART00000073895
membrane bound O-acyltransferase domain containing 4
chr5_+_35458346 0.28 ENSDART00000141239
ER lipid raft associated 2
chr19_-_18152407 0.28 ENSDART00000193264
ENSDART00000016135
nuclear factor, erythroid 2-like 3
chr12_-_5188413 0.28 ENSDART00000161988
FRA10A associated CGG repeat 1
chr2_+_49457449 0.27 ENSDART00000185470
SH3-domain GRB2-like 1a
chr7_-_73852594 0.27 ENSDART00000183194
zgc:165555
chr5_-_21422390 0.27 ENSDART00000144198
teneurin transmembrane protein 1
chr22_-_24967348 0.26 ENSDART00000153490
ENSDART00000084871
family with sequence similarity 20, member C like
chr2_-_30784198 0.26 ENSDART00000182523
ENSDART00000147355
regulator of G protein signaling 20
chr7_-_40145097 0.26 ENSDART00000173634
WD repeat domain 60
chr19_+_24575077 0.25 ENSDART00000167469
si:dkeyp-92c9.4
chr19_-_27339844 0.25 ENSDART00000052358
ENSDART00000148238
ENSDART00000147661
ENSDART00000137346
zinc ribbon domain containing 1
chr21_+_34119759 0.24 ENSDART00000024750
ENSDART00000128242
high mobility group box 3b
chr16_+_27349585 0.23 ENSDART00000142573
nuclear receptor subfamily 4, group A, member 3
chr24_-_29868151 0.22 ENSDART00000184802
amylo-alpha-1, 6-glucosidase, 4-alpha-glucanotransferase b
chr25_-_22889519 0.22 ENSDART00000128250
MOB kinase activator 2a
chr7_+_22688781 0.22 ENSDART00000173509
UDP glucuronosyltransferase 5 family, polypeptide G1
chr12_-_28956921 0.22 ENSDART00000142933
zinc finger protein 646
chr3_-_9444749 0.21 ENSDART00000182191

chr1_+_39995008 0.21 ENSDART00000166251
aryl hydrocarbon receptor interacting protein
chr8_+_17069577 0.21 ENSDART00000131847
si:dkey-190g11.3
chr10_-_26163989 0.20 ENSDART00000136472
tripartite motif containing 3b
chr20_-_33961697 0.20 ENSDART00000061765
selectin P
chr12_+_40810418 0.20 ENSDART00000183393
cadherin 18
chr5_+_42912966 0.20 ENSDART00000039973
RUN and FYVE domain containing 3
chr22_+_3045495 0.19 ENSDART00000164061

chr11_-_3381343 0.18 ENSDART00000002545
microspherule protein 1
chr1_+_26480890 0.17 ENSDART00000164430
USO1 vesicle transport factor
chr22_-_10541372 0.17 ENSDART00000179708
si:dkey-42i9.4
chr7_+_31145386 0.16 ENSDART00000075407
ENSDART00000169462
family with sequence similarity 189, member A1
chr16_+_25245857 0.16 ENSDART00000155220
kelch-like family member 38b
chr17_+_33226955 0.16 ENSDART00000063333
proopiomelanocortin a
chr10_-_36633882 0.15 ENSDART00000077161
ENSDART00000137688
remodeling and spacing factor 1b, tandem duplicate 1
remodeling and spacing factor 1b, tandem duplicate 1
chr20_-_14665002 0.15 ENSDART00000152816
secernin 2
chr15_-_5239536 0.15 ENSDART00000081704
odorant receptor, family E, subfamily 128, member 2
chr13_+_47050726 0.15 ENSDART00000140045
anaphase promoting complex subunit 1
chr15_-_9321921 0.15 ENSDART00000159676
ENSDART00000033411
trafficking protein particle complex 4
chr7_+_24006875 0.14 ENSDART00000033755
homeobox and leucine zipper encoding b
chr7_+_38255418 0.13 ENSDART00000052354
si:dkey-78a14.4
chr21_-_43550120 0.13 ENSDART00000151627
si:ch73-362m14.2
chr19_-_43226124 0.13 ENSDART00000168965
gonadotropin releasing hormone receptor 1
chr10_-_42131408 0.12 ENSDART00000076693
STAM binding protein a
chr20_+_37295006 0.11 ENSDART00000153137
connexin 23
chr2_+_26479676 0.10 ENSDART00000056795
ENSDART00000144837
HECT domain containing 3
chr23_-_7826849 0.09 ENSDART00000157612
myelin transcription factor 1b
chr15_+_31481939 0.09 ENSDART00000134306
odorant receptor, family C, subfamily 102, member 5
chr20_-_25877793 0.09 ENSDART00000177333
ENSDART00000184619
exocyst complex component 1
chr12_-_17655683 0.09 ENSDART00000066411
discs, large (Drosophila) homolog-associated protein 5
chr6_-_29537219 0.09 ENSDART00000180262
peroxisomal biogenesis factor 5-like a
chr10_+_29849497 0.09 ENSDART00000099994
ENSDART00000132212
heat shock protein 8
chr6_-_51101834 0.09 ENSDART00000092493
protein tyrosine phosphatase, receptor type, t
chr17_-_35238359 0.09 ENSDART00000005784
integrin beta 1 binding protein 1
chr22_-_15693085 0.09 ENSDART00000141861
si:ch1073-396h14.1
chr2_-_13268556 0.08 ENSDART00000127693
ENSDART00000079757
vacuolar protein sorting 4b homolog B (S. cerevisiae)
chr16_-_21799407 0.07 ENSDART00000123717

chr21_+_349091 0.07 ENSDART00000183693
zinc finger protein 462
chr7_-_6604623 0.07 ENSDART00000172874
potassium inwardly-rectifying channel, subfamily J, member 10a
chr23_+_30827959 0.06 ENSDART00000033429
neuropeptides B/W receptor 2a
chr17_+_26208630 0.06 ENSDART00000087084
glutamate receptor, ionotropic, delta 1a
chr6_+_52889353 0.05 ENSDART00000174115
odorant receptor, family H, subfamily 137, member 9
chr19_+_4038589 0.05 ENSDART00000169271
bloodthirsty-related gene family, member 23
chr15_-_20779624 0.05 ENSDART00000181936
tyrosylprotein sulfotransferase 1
chr13_-_11699530 0.04 ENSDART00000192161
solute carrier family 39 (zinc transporter), member 8
chr14_+_11946395 0.04 ENSDART00000193290
FERM and PDZ domain containing 3
chr25_+_13271458 0.03 ENSDART00000188307

chr9_-_9242777 0.03 ENSDART00000021191
U2 small nuclear RNA auxiliary factor 1
chr12_+_33151246 0.03 ENSDART00000162681
RNA binding fox-1 homolog 3a
chr3_-_21402279 0.02 ENSDART00000164513

chr10_-_42237304 0.02 ENSDART00000140341
transcription factor 7 like 1a
chr12_-_22524388 0.01 ENSDART00000020942
sex hormone-binding globulin
chr15_-_41503392 0.01 ENSDART00000169351
si:dkey-230i18.2
chr3_+_3545825 0.01 ENSDART00000109060

chr21_-_21600640 0.01 ENSDART00000079495
odorant receptor, family H, subfamily 133, member 1
chr7_-_24373662 0.01 ENSDART00000173865
si:dkey-11k2.7
chr25_+_26798673 0.01 ENSDART00000157235
carbonic anhydrase XII

Network of associatons between targets according to the STRING database.

First level regulatory network of sox6

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 1.8 GO:0016338 calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules(GO:0016338)
0.4 1.1 GO:0015882 L-ascorbic acid transport(GO:0015882) L-ascorbic acid metabolic process(GO:0019852)
0.3 1.0 GO:0002155 regulation of thyroid hormone mediated signaling pathway(GO:0002155)
0.3 1.0 GO:0035666 regulation of natural killer cell activation(GO:0032814) positive regulation of natural killer cell activation(GO:0032816) TRIF-dependent toll-like receptor signaling pathway(GO:0035666)
0.3 0.8 GO:1901407 regulation of phosphorylation of RNA polymerase II C-terminal domain(GO:1901407)
0.3 1.0 GO:0070987 error-free translesion synthesis(GO:0070987)
0.3 1.3 GO:0010481 epidermal cell division(GO:0010481) regulation of epidermal cell division(GO:0010482)
0.2 4.0 GO:0007339 binding of sperm to zona pellucida(GO:0007339) egg coat formation(GO:0035803) regulation of acrosome reaction(GO:0060046) positive regulation of acrosome reaction(GO:2000344)
0.2 0.7 GO:1901223 negative regulation of NIK/NF-kappaB signaling(GO:1901223)
0.2 0.7 GO:0042730 fibrinolysis(GO:0042730)
0.2 0.7 GO:1904983 transmembrane glycine transport from cytosol to mitochondrion(GO:1904983)
0.2 0.5 GO:0018872 arsonoacetate metabolic process(GO:0018872)
0.1 0.6 GO:0051444 negative regulation of ligase activity(GO:0051352) negative regulation of ubiquitin-protein transferase activity(GO:0051444) negative regulation of ubiquitin protein ligase activity(GO:1904667)
0.1 1.3 GO:0030719 P granule organization(GO:0030719)
0.1 0.9 GO:1900077 negative regulation of insulin receptor signaling pathway(GO:0046627) negative regulation of cellular response to insulin stimulus(GO:1900077)
0.1 0.6 GO:0090133 adherens junction maintenance(GO:0034334) mesendoderm migration(GO:0090133) cell migration involved in mesendoderm migration(GO:0090134)
0.1 1.0 GO:0032196 transposition(GO:0032196)
0.1 0.5 GO:1900028 wound healing, spreading of epidermal cells(GO:0035313) negative regulation of ruffle assembly(GO:1900028)
0.1 0.3 GO:0061469 regulation of type B pancreatic cell proliferation(GO:0061469)
0.1 0.6 GO:0043584 nose development(GO:0043584)
0.1 3.4 GO:0032007 negative regulation of TOR signaling(GO:0032007)
0.1 0.8 GO:0050435 beta-amyloid metabolic process(GO:0050435)
0.1 1.6 GO:0070897 DNA-templated transcriptional preinitiation complex assembly(GO:0070897)
0.1 0.6 GO:0006465 signal peptide processing(GO:0006465)
0.1 0.3 GO:0060019 radial glial cell differentiation(GO:0060019)
0.1 0.3 GO:0070166 enamel mineralization(GO:0070166)
0.1 0.4 GO:0030033 microvillus assembly(GO:0030033) microvillus organization(GO:0032528)
0.1 0.5 GO:0035479 angioblast cell migration from lateral mesoderm to midline(GO:0035479)
0.1 0.6 GO:0072383 plus-end-directed vesicle transport along microtubule(GO:0072383) plus-end-directed organelle transport along microtubule(GO:0072386)
0.1 0.5 GO:0007096 regulation of exit from mitosis(GO:0007096)
0.1 0.2 GO:0002191 cap-dependent translational initiation(GO:0002191)
0.1 0.8 GO:0046599 regulation of centriole replication(GO:0046599)
0.0 0.3 GO:0034389 lipid particle organization(GO:0034389)
0.0 0.2 GO:0048211 Golgi vesicle docking(GO:0048211)
0.0 0.2 GO:0097241 hematopoietic stem cell migration to bone marrow(GO:0097241)
0.0 0.6 GO:0006198 cAMP catabolic process(GO:0006198)
0.0 0.6 GO:0032467 positive regulation of cytokinesis(GO:0032467)
0.0 0.5 GO:0010738 regulation of protein kinase A signaling(GO:0010738)
0.0 0.2 GO:0071376 response to corticotropin-releasing hormone(GO:0043435) cellular response to corticotropin-releasing hormone stimulus(GO:0071376)
0.0 0.3 GO:0032094 response to food(GO:0032094)
0.0 0.1 GO:0003322 pancreatic A cell development(GO:0003322)
0.0 0.6 GO:0034472 snRNA 3'-end processing(GO:0034472)
0.0 0.3 GO:0032933 response to sterol depletion(GO:0006991) SREBP signaling pathway(GO:0032933) cellular response to sterol depletion(GO:0071501)
0.0 0.1 GO:0050911 detection of chemical stimulus involved in sensory perception of smell(GO:0050911)
0.0 0.5 GO:0051489 regulation of filopodium assembly(GO:0051489)
0.0 1.9 GO:0015718 monocarboxylic acid transport(GO:0015718)
0.0 0.4 GO:0006383 transcription from RNA polymerase III promoter(GO:0006383)
0.0 0.4 GO:0006744 ubiquinone metabolic process(GO:0006743) ubiquinone biosynthetic process(GO:0006744) quinone biosynthetic process(GO:1901663)
0.0 0.8 GO:0018298 protein-chromophore linkage(GO:0018298)
0.0 1.0 GO:0030901 midbrain development(GO:0030901)
0.0 0.6 GO:0042073 intraciliary transport(GO:0042073)
0.0 0.2 GO:0005980 polysaccharide catabolic process(GO:0000272) glycogen catabolic process(GO:0005980) glucan catabolic process(GO:0009251) cellular polysaccharide catabolic process(GO:0044247)
0.0 0.0 GO:0071421 manganese ion transmembrane transport(GO:0071421)
0.0 0.1 GO:1902946 positive regulation of receptor-mediated endocytosis(GO:0048260) protein localization to early endosome(GO:1902946)
0.0 0.1 GO:0070979 protein K11-linked ubiquitination(GO:0070979)
0.0 0.2 GO:0048026 positive regulation of mRNA splicing, via spliceosome(GO:0048026)
0.0 1.1 GO:0006334 nucleosome assembly(GO:0006334)
0.0 0.9 GO:0034504 protein localization to nucleus(GO:0034504)
0.0 0.2 GO:0018023 peptidyl-lysine trimethylation(GO:0018023)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 1.3 GO:0033391 chromatoid body(GO:0033391)
0.2 1.6 GO:0000126 transcription factor TFIIIB complex(GO:0000126)
0.2 0.6 GO:0071556 integral component of cytoplasmic side of endoplasmic reticulum membrane(GO:0071458) integral component of lumenal side of endoplasmic reticulum membrane(GO:0071556) lumenal side of endoplasmic reticulum membrane(GO:0098553)
0.1 0.8 GO:0031907 peroxisomal matrix(GO:0005782) microbody lumen(GO:0031907)
0.1 0.5 GO:0044326 dendritic spine neck(GO:0044326) dendritic filopodium(GO:1902737)
0.1 0.3 GO:0036396 MIS complex(GO:0036396) mRNA editing complex(GO:0045293)
0.1 0.5 GO:0043194 axon initial segment(GO:0043194)
0.1 0.2 GO:0031213 RSF complex(GO:0031213)
0.0 0.6 GO:0005868 cytoplasmic dynein complex(GO:0005868)
0.0 0.6 GO:0030057 desmosome(GO:0030057)
0.0 0.6 GO:0032039 integrator complex(GO:0032039)
0.0 0.4 GO:0005666 DNA-directed RNA polymerase III complex(GO:0005666)
0.0 0.4 GO:0030687 preribosome, large subunit precursor(GO:0030687)
0.0 0.3 GO:0005689 U12-type spliceosomal complex(GO:0005689)
0.0 1.8 GO:0005923 bicellular tight junction(GO:0005923) occluding junction(GO:0070160)
0.0 1.2 GO:0005871 kinesin complex(GO:0005871)
0.0 1.2 GO:0001726 ruffle(GO:0001726)
0.0 0.2 GO:0044545 NSL complex(GO:0044545)
0.0 0.1 GO:0031616 spindle pole centrosome(GO:0031616)
0.0 1.1 GO:0000786 nucleosome(GO:0000786)
0.0 0.8 GO:0005814 centriole(GO:0005814)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.9 3.4 GO:0071889 14-3-3 protein binding(GO:0071889)
0.4 4.0 GO:0035804 structural constituent of egg coat(GO:0035804)
0.2 0.7 GO:0072590 N-acetyl-L-aspartate-L-glutamate ligase activity(GO:0072590) citrate-L-glutamate ligase activity(GO:0072591)
0.2 1.6 GO:0000995 transcription factor activity, core RNA polymerase III binding(GO:0000995)
0.2 1.9 GO:0015129 lactate transmembrane transporter activity(GO:0015129)
0.2 0.5 GO:0030791 arsenite methyltransferase activity(GO:0030791) methylarsonite methyltransferase activity(GO:0030792)
0.1 0.3 GO:0001734 mRNA (N6-adenosine)-methyltransferase activity(GO:0001734)
0.1 0.4 GO:0016842 amidine-lyase activity(GO:0016842)
0.1 0.6 GO:0042500 aspartic endopeptidase activity, intramembrane cleaving(GO:0042500)
0.1 0.9 GO:0005158 insulin receptor binding(GO:0005158)
0.1 0.9 GO:0004711 ribosomal protein S6 kinase activity(GO:0004711)
0.1 0.8 GO:0070577 lysine-acetylated histone binding(GO:0070577)
0.1 0.8 GO:0005332 gamma-aminobutyric acid:sodium symporter activity(GO:0005332)
0.1 0.2 GO:0098808 mRNA cap binding(GO:0098808)
0.1 0.2 GO:0004133 glycogen debranching enzyme activity(GO:0004133) 4-alpha-glucanotransferase activity(GO:0004134) amylo-alpha-1,6-glucosidase activity(GO:0004135)
0.0 0.7 GO:0015187 glycine transmembrane transporter activity(GO:0015187)
0.0 0.6 GO:0001965 G-protein alpha-subunit binding(GO:0001965)
0.0 1.0 GO:0003887 DNA-directed DNA polymerase activity(GO:0003887)
0.0 0.2 GO:0002151 G-quadruplex RNA binding(GO:0002151)
0.0 0.3 GO:0019992 diacylglycerol binding(GO:0019992)
0.0 0.5 GO:0008568 microtubule-severing ATPase activity(GO:0008568)
0.0 0.4 GO:0048039 ubiquinone binding(GO:0048039)
0.0 0.1 GO:0004968 gonadotropin-releasing hormone receptor activity(GO:0004968)
0.0 0.3 GO:0034647 histone demethylase activity (H3-trimethyl-K4 specific)(GO:0034647)
0.0 0.4 GO:0016864 protein disulfide isomerase activity(GO:0003756) intramolecular oxidoreductase activity, transposing S-S bonds(GO:0016864)
0.0 0.2 GO:0070004 cysteine-type exopeptidase activity(GO:0070004)
0.0 0.4 GO:0045503 dynein light chain binding(GO:0045503)
0.0 0.6 GO:0004115 3',5'-cyclic-AMP phosphodiesterase activity(GO:0004115)
0.0 0.5 GO:0034237 protein kinase A regulatory subunit binding(GO:0034237)
0.0 0.1 GO:0004060 arylamine N-acetyltransferase activity(GO:0004060)
0.0 0.1 GO:0004984 olfactory receptor activity(GO:0004984) odorant binding(GO:0005549)
0.0 0.2 GO:0035259 glucocorticoid receptor binding(GO:0035259)
0.0 0.4 GO:0003899 DNA-directed RNA polymerase activity(GO:0003899) RNA polymerase activity(GO:0034062)
0.0 0.8 GO:0008020 G-protein coupled photoreceptor activity(GO:0008020)
0.0 1.1 GO:0005044 scavenger receptor activity(GO:0005044)
0.0 0.2 GO:0008301 DNA binding, bending(GO:0008301)
0.0 1.1 GO:0016811 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides(GO:0016811)
0.0 0.7 GO:0005178 integrin binding(GO:0005178)
0.0 0.1 GO:0005052 peroxisome matrix targeting signal-1 binding(GO:0005052)
0.0 0.5 GO:0045182 translation regulator activity(GO:0045182)
0.0 1.2 GO:0003777 microtubule motor activity(GO:0003777)
0.0 0.4 GO:0019003 GDP binding(GO:0019003)
0.0 1.3 GO:0004843 thiol-dependent ubiquitin-specific protease activity(GO:0004843) thiol-dependent ubiquitinyl hydrolase activity(GO:0036459) ubiquitinyl hydrolase activity(GO:0101005)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 4.3 PID MTOR 4PATHWAY mTOR signaling pathway
0.1 1.0 PID TOLL ENDOGENOUS PATHWAY Endogenous TLR signaling
0.0 0.2 ST PHOSPHOINOSITIDE 3 KINASE PATHWAY PI3K Pathway
0.0 0.8 SIG INSULIN RECEPTOR PATHWAY IN CARDIAC MYOCYTES Genes related to the insulin receptor pathway
0.0 0.6 PID ECADHERIN KERATINOCYTE PATHWAY E-cadherin signaling in keratinocytes
0.0 0.6 PID PLK1 PATHWAY PLK1 signaling events
0.0 0.1 PID SYNDECAN 2 PATHWAY Syndecan-2-mediated signaling events

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.6 REACTOME APOPTOTIC CLEAVAGE OF CELL ADHESION PROTEINS Genes involved in Apoptotic cleavage of cell adhesion proteins
0.2 0.7 REACTOME REGULATION OF COMPLEMENT CASCADE Genes involved in Regulation of Complement cascade
0.1 1.9 REACTOME BILE SALT AND ORGANIC ANION SLC TRANSPORTERS Genes involved in Bile salt and organic anion SLC transporters
0.1 1.0 REACTOME IKK COMPLEX RECRUITMENT MEDIATED BY RIP1 Genes involved in IKK complex recruitment mediated by RIP1
0.1 0.9 REACTOME CREB PHOSPHORYLATION THROUGH THE ACTIVATION OF RAS Genes involved in CREB phosphorylation through the activation of Ras
0.0 1.8 REACTOME ASSOCIATION OF TRIC CCT WITH TARGET PROTEINS DURING BIOSYNTHESIS Genes involved in Association of TriC/CCT with target proteins during biosynthesis
0.0 0.4 REACTOME ACYL CHAIN REMODELLING OF PE Genes involved in Acyl chain remodelling of PE
0.0 0.6 REACTOME KINESINS Genes involved in Kinesins
0.0 0.7 REACTOME KERATAN SULFATE BIOSYNTHESIS Genes involved in Keratan sulfate biosynthesis
0.0 0.3 REACTOME SYNTHESIS SECRETION AND DEACYLATION OF GHRELIN Genes involved in Synthesis, Secretion, and Deacylation of Ghrelin
0.0 0.4 REACTOME DARPP 32 EVENTS Genes involved in DARPP-32 events
0.0 0.6 REACTOME G1 S SPECIFIC TRANSCRIPTION Genes involved in G1/S-Specific Transcription
0.0 1.1 REACTOME METABOLISM OF VITAMINS AND COFACTORS Genes involved in Metabolism of vitamins and cofactors
0.0 0.8 REACTOME LOSS OF NLP FROM MITOTIC CENTROSOMES Genes involved in Loss of Nlp from mitotic centrosomes