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PRJNA195909:zebrafish embryo and larva development
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Results for sox21b
Z-value: 0.55
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Transcription factors associated with sox21b
Activity-expression correlation:
| Gene | Promoter | Pearson corr. coef. | P-value | Plot |
|---|---|---|---|---|
| sox21b | dr11_v1_chr9_+_53276356_53276356 | 0.13 | 7.3e-01 | Click! |
| Promoter | Log-likelihood | Transcript | Gene | Gene Info |
|---|---|---|---|---|
| chr8_-_33154677 Show fit | 0.46 |
ENSDART00000133300
|
zinc finger and BTB domain containing 34 |
|
| chr14_+_49135264 Show fit | 0.37 |
ENSDART00000084119
|
si:ch1073-44g3.1 |
|
| chr8_-_1838315 Show fit | 0.34 |
ENSDART00000114476
ENSDART00000140077 |
phosphatidylinositol 4-kinase, catalytic, alpha b |
|
| chr5_-_15494164 Show fit | 0.32 |
ENSDART00000140668
ENSDART00000188076 ENSDART00000085943 |
TAO kinase 3a |
|
| chr22_-_22337382 Show fit | 0.26 |
ENSDART00000144684
|
si:ch211-129c21.1 |
|
| chr4_+_75200467 Show fit | 0.26 |
ENSDART00000122593
|
|
|
| chr22_+_12798569 Show fit | 0.25 |
ENSDART00000005720
|
signal transducer and activator of transcription 1a |
|
| chr21_-_42007213 Show fit | 0.23 |
ENSDART00000188804
ENSDART00000092821 ENSDART00000165743 |
gamma-aminobutyric acid (GABA) A receptor, gamma 2 |
|
| chr5_-_1203455 Show fit | 0.23 |
ENSDART00000172177
|
surfeit gene 4 |
|
| chr9_-_6661657 Show fit | 0.23 |
ENSDART00000133178
ENSDART00000113914 ENSDART00000061593 |
POU class 3 homeobox 3a |
Network of associatons between targets according to the STRING database.
First level regulatory network of sox21b
Gene Ontology Analysis
Gene overrepresentation in biological process category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.1 | 0.4 | GO:0070208 | protein heterotrimerization(GO:0070208) |
| 0.0 | 0.4 | GO:0016525 | negative regulation of angiogenesis(GO:0016525) |
| 0.1 | 0.3 | GO:0010693 | regulation of alkaline phosphatase activity(GO:0010692) negative regulation of alkaline phosphatase activity(GO:0010693) |
| 0.0 | 0.3 | GO:0046051 | UTP biosynthetic process(GO:0006228) UTP metabolic process(GO:0046051) |
| 0.0 | 0.2 | GO:0038026 | reelin-mediated signaling pathway(GO:0038026) |
| 0.0 | 0.2 | GO:0009312 | oligosaccharide biosynthetic process(GO:0009312) |
| 0.0 | 0.2 | GO:0060337 | response to type I interferon(GO:0034340) type I interferon signaling pathway(GO:0060337) cellular response to type I interferon(GO:0071357) |
| 0.0 | 0.2 | GO:0099550 | trans-synaptic signalling, modulating synaptic transmission(GO:0099550) |
| 0.0 | 0.2 | GO:0036072 | intramembranous ossification(GO:0001957) direct ossification(GO:0036072) |
| 0.0 | 0.2 | GO:0038007 | netrin-activated signaling pathway(GO:0038007) |
Gene overrepresentation in cellular component category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 0.5 | GO:1902710 | GABA receptor complex(GO:1902710) GABA-A receptor complex(GO:1902711) |
| 0.0 | 0.2 | GO:0017119 | Golgi transport complex(GO:0017119) |
| 0.0 | 0.1 | GO:0071065 | alpha9-beta1 integrin-vascular cell adhesion molecule-1 complex(GO:0071065) |
| 0.0 | 0.1 | GO:0070319 | Golgi to plasma membrane transport vesicle(GO:0070319) |
| 0.0 | 0.1 | GO:0071595 | Nem1-Spo7 phosphatase complex(GO:0071595) |
| 0.0 | 0.1 | GO:0008247 | 1-alkyl-2-acetylglycerophosphocholine esterase complex(GO:0008247) |
| 0.0 | 0.1 | GO:0005672 | transcription factor TFIIA complex(GO:0005672) |
| 0.0 | 0.1 | GO:0098888 | presynaptic endocytic zone(GO:0098833) presynaptic endocytic zone membrane(GO:0098835) extrinsic component of presynaptic membrane(GO:0098888) extrinsic component of presynaptic endocytic zone(GO:0098894) |
| 0.0 | 0.1 | GO:0061617 | MICOS complex(GO:0061617) |
| 0.0 | 0.0 | GO:0031251 | PAN complex(GO:0031251) |
Gene overrepresentation in molecular function category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 0.4 | GO:0022851 | benzodiazepine receptor activity(GO:0008503) GABA-gated chloride ion channel activity(GO:0022851) |
| 0.0 | 0.3 | GO:0004430 | 1-phosphatidylinositol 4-kinase activity(GO:0004430) |
| 0.0 | 0.3 | GO:0004550 | nucleoside diphosphate kinase activity(GO:0004550) |
| 0.0 | 0.2 | GO:0003958 | NADPH-hemoprotein reductase activity(GO:0003958) |
| 0.0 | 0.2 | GO:0004743 | pyruvate kinase activity(GO:0004743) |
| 0.0 | 0.2 | GO:0004711 | ribosomal protein S6 kinase activity(GO:0004711) |
| 0.0 | 0.2 | GO:0005042 | netrin receptor activity(GO:0005042) |
| 0.0 | 0.2 | GO:0038191 | neuropilin binding(GO:0038191) |
| 0.0 | 0.2 | GO:0003873 | 6-phosphofructo-2-kinase activity(GO:0003873) |
| 0.0 | 0.1 | GO:0000035 | acyl binding(GO:0000035) |
Gene overrepresentation in curated gene sets: canonical pathways category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 0.2 | PID ANTHRAX PATHWAY | Cellular roles of Anthrax toxin |
| 0.0 | 0.1 | PID LPA4 PATHWAY | LPA4-mediated signaling events |
Gene overrepresentation in curated gene sets: REACTOME pathways category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 0.4 | REACTOME GABA A RECEPTOR ACTIVATION | Genes involved in GABA A receptor activation |
| 0.0 | 0.2 | REACTOME RAF MAP KINASE CASCADE | Genes involved in RAF/MAP kinase cascade |
| 0.0 | 0.2 | REACTOME TRANSPORT OF ORGANIC ANIONS | Genes involved in Transport of organic anions |
| 0.0 | 0.1 | REACTOME OLFACTORY SIGNALING PATHWAY | Genes involved in Olfactory Signaling Pathway |
| 0.0 | 0.1 | REACTOME REGULATION OF RHEB GTPASE ACTIVITY BY AMPK | Genes involved in Regulation of Rheb GTPase activity by AMPK |