Project

PRJNA195909:zebrafish embryo and larva development

Navigation
Downloads

Results for sox17

Z-value: 0.82

Motif logo

Transcription factors associated with sox17

Gene Symbol Gene ID Gene Info
ENSDARG00000101717 SRY-box transcription factor 17

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
sox17dr11_v1_chr7_-_58776400_58776400-0.531.4e-01Click!

Activity profile of sox17 motif

Sorted Z-values of sox17 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr18_+_20560616 1.92 ENSDART00000136710
ENSDART00000151974
ENSDART00000121699
ENSDART00000040074
WEE1 homolog 2 (S. pombe)
chr5_-_15264007 1.09 ENSDART00000180641
guanine nucleotide binding protein (G protein), beta polypeptide 1-like
chr6_+_54498220 1.02 ENSDART00000103282
si:ch211-233f11.5
chr16_+_50741154 0.96 ENSDART00000101627
zgc:110372
chr8_-_44611357 0.88 ENSDART00000063396
BCL2 associated athanogene 4
chr9_-_16218097 0.83 ENSDART00000190503
myosin IB
chr1_+_53321878 0.81 ENSDART00000143909
TBC1 domain family, member 9 (with GRAM domain)
chr3_+_18437397 0.81 ENSDART00000136243
ENSDART00000184882
ENSDART00000135470
TBC1 domain family, member 16
chr13_-_35765028 0.78 ENSDART00000157391
endoplasmic reticulum lectin 1
chr22_+_25274712 0.75 ENSDART00000137341

chr17_+_16423721 0.73 ENSDART00000064233
EF-hand calcium binding domain 11
chr24_-_10021341 0.72 ENSDART00000137250
zgc:173856
chr24_+_31459715 0.72 ENSDART00000181102
ENSDART00000189950
ENSDART00000192321
ENSDART00000126380
cyclic nucleotide binding domain containing 1
chr8_+_13368150 0.72 ENSDART00000114699
solute carrier family 5 (sodium/iodide cotransporter), member 5
chr23_+_32101361 0.72 ENSDART00000138849
zgc:56699
chr12_-_30359498 0.71 ENSDART00000152981
ENSDART00000189988
tudor domain containing 1
chr12_-_30358836 0.70 ENSDART00000152878
tudor domain containing 1
chr12_-_30359031 0.70 ENSDART00000192628
tudor domain containing 1
chr19_+_42886413 0.70 ENSDART00000151298
cAMP-regulated phosphoprotein, 21
chr11_-_42134968 0.69 ENSDART00000187115

chr9_+_16854121 0.69 ENSDART00000110866
CLN5, intracellular trafficking protein
chr3_-_55525627 0.69 ENSDART00000189234
testis expressed 2
chr5_-_20678300 0.68 ENSDART00000088639
WSC domain containing 2
chr3_+_35005730 0.68 ENSDART00000029451
protein kinase C, beta b
chr17_-_12058171 0.68 ENSDART00000105236
SET and MYND domain containing 3
chr17_-_2584423 0.68 ENSDART00000013506
zona pellucida glycoprotein 3, tandem duplicate 2
chr19_+_42432625 0.67 ENSDART00000076938
pogo transposable element derived with ZNF domain a
chr11_-_27537593 0.66 ENSDART00000173444
ENSDART00000172895
ENSDART00000088177
protein tyrosine phosphatase domain containing 1a
chr15_-_18209672 0.66 ENSDART00000141508
ENSDART00000136280
bloodthirsty-related gene family, member 16
chr16_-_41717063 0.65 ENSDART00000084610
centrosomal protein 85
chr18_+_17534627 0.64 ENSDART00000061007
metallothionein 2
chr2_-_26596794 0.64 ENSDART00000134685
ENSDART00000056787
zgc:113691
chr6_+_30533504 0.64 ENSDART00000155842
WWC family member 3
chr15_-_28904371 0.64 ENSDART00000155154
echinoderm microtubule associated protein like 2
chr14_-_24101897 0.61 ENSDART00000143695
cytoplasmic polyadenylation element binding protein 4a
chr2_-_17492486 0.61 ENSDART00000189464
lysine (K)-specific demethylase 4A, genome duplicate b
chr10_+_15454745 0.60 ENSDART00000129441
ENSDART00000123935
ENSDART00000163446
ENSDART00000087680
ENSDART00000193752
erbb2 interacting protein
chr10_-_3258073 0.60 ENSDART00000113162
phosphatidylinositol 4-kinase, catalytic, alpha a
chr1_-_46650022 0.59 ENSDART00000148759
ENSDART00000053222
regulator of chromosome condensation (RCC1) and BTB (POZ) domain containing protein 1
chr9_-_46276626 0.59 ENSDART00000165238
histone deacetylase 4
chr2_-_17492080 0.58 ENSDART00000024302
lysine (K)-specific demethylase 4A, genome duplicate b
chr4_-_3145359 0.58 ENSDART00000112210
pleckstrin homology domain containing, family A member 5
chr20_-_45062514 0.57 ENSDART00000183529
ENSDART00000182955
kelch-like family member 29
chr24_+_10027902 0.57 ENSDART00000175961
ENSDART00000172773
si:ch211-146l10.8
chr17_+_13031497 0.57 ENSDART00000115208
F-box protein 33
chr23_+_42254960 0.56 ENSDART00000102980
zinc finger, CCHC domain containing 11
chr23_+_16774589 0.56 ENSDART00000104791
zgc:153722
chr21_+_12036238 0.55 ENSDART00000102463
ENSDART00000155426
zgc:162344
chr5_+_37504309 0.55 ENSDART00000165465
si:ch1073-224n8.1
chr16_-_31598771 0.55 ENSDART00000016386
thyroglobulin
chr21_-_39546737 0.54 ENSDART00000006971
septin 4a
chr22_+_14051245 0.54 ENSDART00000043711
ENSDART00000164259
aldehyde oxidase 6
chr20_-_45060241 0.54 ENSDART00000185227
kelch-like family member 29
chr24_+_26406770 0.53 ENSDART00000110011
si:ch211-230g15.5
chr25_+_3104959 0.53 ENSDART00000167130
RAB3A interacting protein (rabin3)-like 1
chr5_-_8602937 0.53 ENSDART00000157765
RPTOR independent companion of MTOR, complex 2 a
chr5_-_30074332 0.52 ENSDART00000147963
beta-carotene oxygenase 2a
chr13_+_31687973 0.52 ENSDART00000076479
solute carrier family 38, member 6
chr12_-_9123352 0.52 ENSDART00000149655
ADAM metallopeptidase domain 8b
chr20_-_18794789 0.51 ENSDART00000003834
cerebral cavernous malformation 2
chr10_-_45029041 0.51 ENSDART00000167878
polymerase (DNA directed), mu
chr7_-_30624435 0.50 ENSDART00000173828
ring finger protein 111
chr11_-_33868881 0.50 ENSDART00000163295
ENSDART00000172633
ENSDART00000171439
si:ch211-227n13.3
chr3_-_12381271 0.49 ENSDART00000171068
ENSDART00000157475
coronin 7
chr25_+_20694177 0.49 ENSDART00000073648
KxDL motif containing 1
chr7_+_23495986 0.48 ENSDART00000190739
ENSDART00000115299
ENSDART00000101423
ENSDART00000142401
zgc:109889
chr4_-_18416566 0.48 ENSDART00000033717
CASP2 and RIPK1 domain containing adaptor with death domain
chr23_+_19655301 0.48 ENSDART00000104441
ENSDART00000135269
abhydrolase domain containing 6b
chr17_+_24222190 0.48 ENSDART00000181698
ENSDART00000189411
EH domain binding protein 1
chr7_+_34592526 0.48 ENSDART00000173959
formin homology 2 domain containing 1
chr18_-_21725805 0.47 ENSDART00000182185
FANCD2/FANCI-associated nuclease 1
chr23_-_24542156 0.46 ENSDART00000132265
ATPase 13A2
chr19_-_25114701 0.46 ENSDART00000149035
protein tyrosine phosphatase type IVA, member 3
chr16_-_33095161 0.46 ENSDART00000187648
dopey family member 1
chr4_+_69801372 0.45 ENSDART00000154125
si:dkey-238o14.7
chr12_-_611367 0.45 ENSDART00000152286
wu:fj29h11
chr4_-_5370859 0.45 ENSDART00000189559
si:dkey-14d8.1
chr21_-_2248239 0.45 ENSDART00000169448
si:ch73-299h12.1
chr7_-_32020100 0.45 ENSDART00000185433
kinesin family member 18A
chr17_-_23895026 0.45 ENSDART00000122108
PDZ domain containing 8
chr23_+_30730121 0.45 ENSDART00000134141
additional sex combs like transcriptional regulator 1
chr8_-_22326073 0.45 ENSDART00000084965
centrosomal protein 104
chr21_+_26748141 0.44 ENSDART00000169025
pyruvate carboxylase a
chr7_+_38349667 0.44 ENSDART00000010046
rhophilin, Rho GTPase binding protein 2
chr4_-_2975461 0.44 ENSDART00000150794
pleckstrin homology domain containing, family A member 5
chr18_-_21725638 0.44 ENSDART00000089853
FANCD2/FANCI-associated nuclease 1
chr6_+_4299164 0.43 ENSDART00000159759
neurobeachin-like 1
chr11_-_44979281 0.43 ENSDART00000190972
LIM-domain binding 1b
chr22_+_14051894 0.43 ENSDART00000142548
aldehyde oxidase 6
chr21_+_6328801 0.43 ENSDART00000163577
formin binding protein 1b
chr14_+_26566936 0.43 ENSDART00000173056
ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 3
chr18_+_44630415 0.43 ENSDART00000098540
BRD4 interacting chromatin remodeling complex associated protein
chr8_+_10339869 0.42 ENSDART00000132253
TBC1 domain family, member 22B
chr22_-_27113332 0.42 ENSDART00000146951
ENSDART00000178855
X-prolyl aminopeptidase (aminopeptidase P) 1, soluble
chr20_+_18945057 0.42 ENSDART00000035447
myotubularin related protein 9
chr10_+_4235998 0.42 ENSDART00000169328
phospholipid phosphatase related 1
chr1_-_23110740 0.42 ENSDART00000171848
ENSDART00000086797
ENSDART00000189344
ENSDART00000190858
adhesion G protein-coupled receptor L3.1
chr22_+_12361489 0.42 ENSDART00000182483
R3H domain containing 1
chr16_-_28658341 0.42 ENSDART00000148456
ATP-binding cassette, sub-family B (MDR/TAP), member 4
chr22_+_32228882 0.41 ENSDART00000092082
mesencephalic astrocyte-derived neurotrophic factor
chr6_+_6828167 0.41 ENSDART00000181284
si:ch211-85n16.4
chr24_+_26997798 0.41 ENSDART00000089506
La ribonucleoprotein domain family, member 4B
chr20_-_31238313 0.41 ENSDART00000028471
hippocalcin-like 1
chr12_-_3077395 0.40 ENSDART00000002867
ENSDART00000126315
RFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase
chr2_+_22409249 0.40 ENSDART00000182915
zgc:56628
chr7_+_66884570 0.40 ENSDART00000082664
SET binding factor 2
chr5_-_57289872 0.40 ENSDART00000189893
ENSDART00000050957
fer (fps/fes related) tyrosine kinase
chr16_-_30826712 0.40 ENSDART00000122474
protein tyrosine kinase 2ab
chr22_+_12361317 0.40 ENSDART00000189963
ENSDART00000159614
R3H domain containing 1
chr15_-_30815826 0.40 ENSDART00000156160
ENSDART00000145918
musashi RNA-binding protein 2b
chr2_+_43204919 0.39 ENSDART00000160077
ENSDART00000018729
ENSDART00000129134
ENSDART00000056402
par-3 family cell polarity regulator alpha, b
chr17_-_20218167 0.39 ENSDART00000154479
O-6-methylguanine-DNA methyltransferase
chr9_-_6618067 0.39 ENSDART00000061585
si:dkeyp-118h3.6
chr6_-_54444929 0.39 ENSDART00000154121
Sys1 golgi trafficking protein
chr21_+_21791343 0.39 ENSDART00000151654
sialidase 3 (membrane sialidase), tandem duplicate 1
chr6_-_39198912 0.38 ENSDART00000077938
core 1 synthase, glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase, 1b
chr23_+_34321237 0.38 ENSDART00000173272
plexin A1a
chr2_+_36109002 0.38 ENSDART00000158978
T-cell receptor alpha joining 28
chr6_+_29923593 0.37 ENSDART00000169687
discs, large homolog 1 (Drosophila)
chr6_-_37513133 0.37 ENSDART00000147826
jade family PHD finger 3
chr3_-_40976463 0.37 ENSDART00000128450
ENSDART00000018676
cytochrome P450, family 3, subfamily c, polypeptide 1
chr23_+_24973773 0.37 ENSDART00000047020
caspase 9, apoptosis-related cysteine peptidase
chr9_-_22057658 0.37 ENSDART00000101944
crystallin, gamma MX, like 1
chr19_+_20495249 0.37 ENSDART00000090810
potassium voltage-gated channel, subfamily H (eag-related), member 8
chr11_+_25539698 0.37 ENSDART00000035602
CXXC finger protein 1b
chr1_-_18772241 0.37 ENSDART00000147645
ENSDART00000133194
ENSDART00000147525
ENSDART00000191493
TBC1 (tre-2/USP6, BUB2, cdc16) domain family, member 1
chr24_-_16979728 0.37 ENSDART00000005331
kelch-like family member 15
chr15_+_20344670 0.36 ENSDART00000158986
pleckstrin homology domain containing, family G (with RhoGef domain) member 2
chr11_-_45385803 0.36 ENSDART00000173329
trafficking protein particle complex 10
chr4_-_3064101 0.36 ENSDART00000135701
pleckstrin homology domain containing, family A member 5
chr24_+_5829265 0.36 ENSDART00000155242
si:ch211-157j23.5
chr11_+_30636351 0.36 ENSDART00000087909
transmembrane protein 246
chr3_+_35611625 0.36 ENSDART00000190995
TNF receptor-associated factor 7
chr21_-_32781612 0.36 ENSDART00000031028
CCR4-NOT transcription complex, subunit 6a
chr1_+_46405294 0.35 ENSDART00000143228
tubulin, gamma complex associated protein 3
chr7_-_18601206 0.35 ENSDART00000111636
si:ch211-119e14.2
chr14_+_16093889 0.35 ENSDART00000159181
inner membrane protein, mitochondrial (mitofilin)
chr5_-_67349916 0.35 ENSDART00000144092
MLX interacting protein
chr16_-_54978981 0.35 ENSDART00000154023
WD and tetratricopeptide repeats 1
chr19_-_20446756 0.35 ENSDART00000140711
TBC1 domain family, member 5
chr6_-_39199070 0.34 ENSDART00000131793
core 1 synthase, glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase, 1b
chr7_+_21917857 0.34 ENSDART00000088041
UFM1-specific peptidase 1 (non-functional)
chr10_-_28027490 0.34 ENSDART00000185445
integrator complex subunit 2
chr5_-_69314495 0.34 ENSDART00000182335
smoothelin b
chr3_+_28860283 0.34 ENSDART00000077235
ALG1, chitobiosyldiphosphodolichol beta-mannosyltransferase
chr2_+_24867534 0.34 ENSDART00000158050
RAB3A, member RAS oncogene family, a
chr12_-_30032188 0.34 ENSDART00000042514
attractin-like 1b
chr20_+_4221978 0.33 ENSDART00000171898
interaction protein for cytohesin exchange factors 1
chr18_+_31117136 0.33 ENSDART00000138403
transcription factor 25 (basic helix-loop-helix)
chr17_-_20218357 0.33 ENSDART00000155990
ENSDART00000155632
ENSDART00000156540
ENSDART00000063523
O-6-methylguanine-DNA methyltransferase
chr12_+_19958845 0.33 ENSDART00000193248
excision repair cross-complementation group 4
chr7_-_28641522 0.33 ENSDART00000182071
solute carrier family 7 (amino acid transporter light chain, y+L system), member 6
chr24_-_25030173 0.33 ENSDART00000126395
ENSDART00000019350
nucleoporin 58
chr18_+_31117323 0.32 ENSDART00000059893
transcription factor 25 (basic helix-loop-helix)
chr1_+_46404968 0.32 ENSDART00000042064
tubulin, gamma complex associated protein 3
chr4_-_28353538 0.32 ENSDART00000064219
tRNA 5-methylaminomethyl-2-thiouridylate methyltransferase
chr4_-_12781182 0.31 ENSDART00000058020
helicase (DNA) B
chr9_+_38457806 0.31 ENSDART00000142512
minichromosome maintenance complex component 3 associated protein
chr21_+_33503835 0.31 ENSDART00000125658
clathrin interactor 1b
chr13_-_533243 0.31 ENSDART00000038315
nuclear VCP-like
chr24_-_27409599 0.31 ENSDART00000041770
chemokine (C-C motif) ligand 34b, duplicate 3
chr6_-_7842078 0.31 ENSDART00000065507
phospholipid phosphatase related 2b
chr16_-_11858009 0.31 ENSDART00000158347
chemokine (C-X-C motif) receptor 3, tandem duplicate 1
chr24_-_12832499 0.31 ENSDART00000182027
ENSDART00000039312
importin 4
chr7_-_71384391 0.31 ENSDART00000112841
coiled-coil domain containing 149a
chr19_+_43905671 0.30 ENSDART00000168725
ENSDART00000133628
ankyrin repeat and IBR domain containing 1a
chr14_+_29609245 0.30 ENSDART00000043058
si:dkey-34l15.2
chr7_+_9041174 0.30 ENSDART00000163411

chr11_-_1948784 0.30 ENSDART00000082475
nuclear receptor subfamily 1, group D, member 4b
chr23_-_36670369 0.30 ENSDART00000006881
zinc finger and BTB domain containing 39
chr2_+_55199721 0.30 ENSDART00000016143
zmp:0000000521
chr20_-_48898371 0.30 ENSDART00000170617
5'-3' exoribonuclease 2
chr24_-_25673405 0.30 ENSDART00000186081
ENSDART00000110241
ENSDART00000142351
connector enhancer of kinase suppressor of Ras 2a
chr18_+_1837668 0.30 ENSDART00000164210

chr5_-_22868650 0.30 ENSDART00000057541
apolipoprotein O-like
chr19_-_24136233 0.29 ENSDART00000143365
THAP domain containing 7
chr17_-_6599484 0.29 ENSDART00000156927
si:ch211-189e2.2
chr10_-_6588793 0.29 ENSDART00000163788
chromodomain helicase DNA binding protein 1
chr16_-_25400257 0.29 ENSDART00000040756
zgc:136493
chr15_-_43768776 0.29 ENSDART00000170398
glutamate receptor, metabotropic 5b
chr5_-_26323137 0.28 ENSDART00000133823
ARVCF, delta catenin family member b
chr22_+_1352192 0.28 ENSDART00000169629
zinc finger 45 like
chr23_+_26017227 0.28 ENSDART00000002939
6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 1
chr6_-_7107868 0.28 ENSDART00000171123
nonhomologous end-joining factor 1
chr14_-_46113321 0.28 ENSDART00000169040
ENSDART00000161475
ENSDART00000124925
si:ch211-235e9.8
chr2_+_51818039 0.28 ENSDART00000170353
activin A receptor type 2Bb
chr13_-_31687925 0.27 ENSDART00000085989
TRM5 tRNA methyltransferase 5 homolog (S. cerevisiae)
chr23_-_33702900 0.27 ENSDART00000187413
POU class 6 homeobox 1
chr1_-_56951369 0.27 ENSDART00000152294
si:ch211-1f22.2
chr5_-_5243079 0.27 ENSDART00000130576
ENSDART00000164377
multivesicular body subunit 12Ba
chr13_-_48431766 0.27 ENSDART00000159688
ENSDART00000171765
F-box protein 11a
chr8_+_42717005 0.27 ENSDART00000181656
ENSDART00000180320
ENSDART00000181293
zgc:194007
chr5_-_33769211 0.27 ENSDART00000133504
DAB2 interacting protein b
chr5_+_36530836 0.27 ENSDART00000006899
immunoglobulin (CD79A) binding protein 1
chr16_-_47301376 0.26 ENSDART00000169697
missing oocyte, meiosis regulator, homolog (Drosophila)
chr23_-_45319592 0.26 ENSDART00000189861
coiled-coil domain containing 171
chr3_+_15773991 0.26 ENSDART00000089923
zinc finger protein 652
chr21_-_21530868 0.26 ENSDART00000174231
odorant receptor, family H, subfamily 133, member 9
chr7_+_5936601 0.26 ENSDART00000181693
si:dkey-23a13.11
chr7_+_34297271 0.26 ENSDART00000180342
butyrobetaine (gamma), 2-oxoglutarate dioxygenase (gamma-butyrobetaine hydroxylase) 1

Network of associatons between targets according to the STRING database.

First level regulatory network of sox17

PNG image of the network

In order to view interactive SVG image please either update your browser to latest version or install SVG plugin.


View svg image
View png image

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 1.9 GO:0040020 regulation of meiotic nuclear division(GO:0040020)
0.2 2.1 GO:0043046 DNA methylation involved in gamete generation(GO:0043046)
0.2 0.5 GO:0051044 positive regulation of membrane protein ectodomain proteolysis(GO:0051044)
0.1 0.6 GO:0090299 regulation of neural crest formation(GO:0090299)
0.1 0.6 GO:0070900 mitochondrial tRNA modification(GO:0070900) mitochondrial RNA modification(GO:1900864)
0.1 0.5 GO:0006590 thyroid hormone generation(GO:0006590)
0.1 0.3 GO:0031630 regulation of synaptic vesicle fusion to presynaptic membrane(GO:0031630)
0.1 0.3 GO:1901255 nucleotide-excision repair involved in interstrand cross-link repair(GO:1901255)
0.1 0.3 GO:0051973 positive regulation of telomerase activity(GO:0051973)
0.1 0.6 GO:0034498 early endosome to Golgi transport(GO:0034498)
0.1 0.9 GO:0033683 nucleotide-excision repair, DNA incision(GO:0033683)
0.1 0.4 GO:0038093 Fc receptor signaling pathway(GO:0038093)
0.1 0.4 GO:0051660 establishment of centrosome localization(GO:0051660)
0.1 0.3 GO:0099553 trans-synaptic signaling by lipid, modulating synaptic transmission(GO:0099552) trans-synaptic signaling by endocannabinoid, modulating synaptic transmission(GO:0099553)
0.1 0.4 GO:0051659 maintenance of mitochondrion location(GO:0051659)
0.1 0.3 GO:0045922 negative regulation of fatty acid metabolic process(GO:0045922)
0.1 0.6 GO:0002931 response to ischemia(GO:0002931)
0.1 0.6 GO:0061298 retina vasculature development in camera-type eye(GO:0061298)
0.1 0.5 GO:0030579 ubiquitin-dependent SMAD protein catabolic process(GO:0030579)
0.1 0.2 GO:0006089 lactate metabolic process(GO:0006089)
0.1 0.3 GO:0006269 DNA replication, synthesis of RNA primer(GO:0006269)
0.1 0.4 GO:0032776 DNA methylation on cytosine(GO:0032776)
0.1 0.2 GO:1905072 cardiac jelly development(GO:1905072)
0.1 0.3 GO:0019068 virion assembly(GO:0019068) virus maturation(GO:0019075) multi-organism membrane organization(GO:0044803) viral budding(GO:0046755) multi-organism organelle organization(GO:1902590) multi-organism membrane budding(GO:1902592)
0.1 0.2 GO:0071498 vitamin K metabolic process(GO:0042373) cellular response to fluid shear stress(GO:0071498)
0.1 0.2 GO:0010265 SCF complex assembly(GO:0010265)
0.1 0.5 GO:0046958 nonassociative learning(GO:0046958) habituation(GO:0046959)
0.1 0.5 GO:0016119 carotene metabolic process(GO:0016119) carotene catabolic process(GO:0016121) terpene metabolic process(GO:0042214) terpene catabolic process(GO:0046247)
0.1 0.6 GO:0070309 lens fiber cell development(GO:0070307) lens fiber cell morphogenesis(GO:0070309)
0.1 0.5 GO:0021588 cerebellum formation(GO:0021588)
0.1 0.2 GO:1903232 melanosome assembly(GO:1903232)
0.1 0.2 GO:0018343 protein farnesylation(GO:0018343)
0.1 0.2 GO:0030220 platelet formation(GO:0030220) platelet morphogenesis(GO:0036344)
0.1 0.5 GO:0006868 glutamine transport(GO:0006868)
0.0 0.2 GO:0071763 nuclear membrane organization(GO:0071763)
0.0 0.2 GO:0031571 mitotic G1 DNA damage checkpoint(GO:0031571)
0.0 0.2 GO:0000012 single strand break repair(GO:0000012)
0.0 0.5 GO:0038203 TORC2 signaling(GO:0038203)
0.0 0.6 GO:0051597 response to methylmercury(GO:0051597)
0.0 0.6 GO:0032088 negative regulation of NF-kappaB transcription factor activity(GO:0032088)
0.0 0.3 GO:0006895 Golgi to endosome transport(GO:0006895)
0.0 0.4 GO:0043981 histone H4-K5 acetylation(GO:0043981) histone H4-K8 acetylation(GO:0043982)
0.0 0.2 GO:0080009 mRNA methylation(GO:0080009)
0.0 0.7 GO:0035803 binding of sperm to zona pellucida(GO:0007339) egg coat formation(GO:0035803) regulation of acrosome reaction(GO:0060046) positive regulation of acrosome reaction(GO:2000344)
0.0 0.2 GO:0005513 detection of calcium ion(GO:0005513)
0.0 0.4 GO:0035284 central nervous system segmentation(GO:0035283) brain segmentation(GO:0035284)
0.0 0.3 GO:0045329 carnitine biosynthetic process(GO:0045329)
0.0 0.3 GO:0030948 negative regulation of vascular endothelial growth factor receptor signaling pathway(GO:0030948) reelin-mediated signaling pathway(GO:0038026)
0.0 0.2 GO:0035989 tendon development(GO:0035989)
0.0 0.4 GO:0009313 oligosaccharide catabolic process(GO:0009313)
0.0 0.1 GO:1904355 positive regulation of telomere maintenance(GO:0032206) regulation of telomere capping(GO:1904353) positive regulation of telomere capping(GO:1904355)
0.0 0.8 GO:0006303 double-strand break repair via nonhomologous end joining(GO:0006303)
0.0 0.6 GO:0016233 telomere capping(GO:0016233)
0.0 0.7 GO:0007020 microtubule nucleation(GO:0007020)
0.0 0.6 GO:1902287 semaphorin-plexin signaling pathway involved in neuron projection guidance(GO:1902285) semaphorin-plexin signaling pathway involved in axon guidance(GO:1902287)
0.0 0.4 GO:0048696 collateral sprouting in absence of injury(GO:0048669) regulation of collateral sprouting in absence of injury(GO:0048696)
0.0 0.7 GO:0030537 larval locomotory behavior(GO:0008345) larval behavior(GO:0030537)
0.0 0.2 GO:0071392 cellular response to estradiol stimulus(GO:0071392)
0.0 0.4 GO:0021988 olfactory bulb development(GO:0021772) olfactory lobe development(GO:0021988)
0.0 0.9 GO:0050821 protein stabilization(GO:0050821)
0.0 0.2 GO:1905066 regulation of canonical Wnt signaling pathway involved in heart development(GO:1905066)
0.0 0.6 GO:0006516 glycoprotein catabolic process(GO:0006516)
0.0 0.2 GO:0018026 peptidyl-lysine monomethylation(GO:0018026)
0.0 0.4 GO:1902807 negative regulation of cell cycle G1/S phase transition(GO:1902807) negative regulation of G1/S transition of mitotic cell cycle(GO:2000134)
0.0 0.2 GO:0016199 axon midline choice point recognition(GO:0016199)
0.0 2.8 GO:0090630 activation of GTPase activity(GO:0090630)
0.0 0.1 GO:0033690 positive regulation of osteoblast proliferation(GO:0033690)
0.0 0.5 GO:0051639 actin filament network formation(GO:0051639)
0.0 0.7 GO:0080171 lysosome organization(GO:0007040) lytic vacuole organization(GO:0080171)
0.0 0.1 GO:0015846 polyamine transport(GO:0015846) polyamine transmembrane transport(GO:1902047) regulation of polyamine transmembrane transport(GO:1902267) positive regulation of polyamine transmembrane transport(GO:1902269)
0.0 0.1 GO:0060397 JAK-STAT cascade involved in growth hormone signaling pathway(GO:0060397)
0.0 0.4 GO:0071542 dopaminergic neuron differentiation(GO:0071542)
0.0 0.2 GO:0032418 lysosome localization(GO:0032418)
0.0 0.5 GO:0051092 positive regulation of NF-kappaB transcription factor activity(GO:0051092)
0.0 1.0 GO:0099515 vesicle transport along actin filament(GO:0030050) actin filament-based transport(GO:0099515)
0.0 0.3 GO:2000601 positive regulation of actin nucleation(GO:0051127) positive regulation of Arp2/3 complex-mediated actin nucleation(GO:2000601)
0.0 0.3 GO:0006003 fructose 2,6-bisphosphate metabolic process(GO:0006003)
0.0 0.2 GO:0032483 regulation of Rab protein signal transduction(GO:0032483)
0.0 0.3 GO:0010738 regulation of protein kinase A signaling(GO:0010738)
0.0 1.0 GO:0034968 histone lysine methylation(GO:0034968)
0.0 0.3 GO:0008089 anterograde axonal transport(GO:0008089)
0.0 0.4 GO:0010507 negative regulation of autophagy(GO:0010507)
0.0 0.2 GO:0042407 cristae formation(GO:0042407)
0.0 0.6 GO:0035118 embryonic pectoral fin morphogenesis(GO:0035118)
0.0 0.4 GO:0009636 response to toxic substance(GO:0009636)
0.0 0.1 GO:0048742 regulation of skeletal muscle fiber development(GO:0048742)
0.0 0.1 GO:0051898 negative regulation of protein kinase B signaling(GO:0051898)
0.0 0.1 GO:0030656 regulation of isoprenoid metabolic process(GO:0019747) hypothalamus cell differentiation(GO:0021979) regulation of vitamin metabolic process(GO:0030656) regulation of retinoic acid biosynthetic process(GO:1900052)
0.0 0.3 GO:0034472 snRNA 3'-end processing(GO:0034472)
0.0 0.4 GO:0050853 B cell receptor signaling pathway(GO:0050853)
0.0 0.2 GO:0090110 cargo loading into COPII-coated vesicle(GO:0090110)
0.0 0.8 GO:0046839 phospholipid dephosphorylation(GO:0046839)
0.0 0.2 GO:0006958 humoral immune response mediated by circulating immunoglobulin(GO:0002455) complement activation, classical pathway(GO:0006958)
0.0 0.6 GO:0031146 SCF-dependent proteasomal ubiquitin-dependent protein catabolic process(GO:0031146)
0.0 0.4 GO:0071391 cellular response to estrogen stimulus(GO:0071391)
0.0 0.3 GO:0032008 positive regulation of TOR signaling(GO:0032008)
0.0 0.2 GO:0046473 phosphatidic acid biosynthetic process(GO:0006654) phosphatidic acid metabolic process(GO:0046473)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 2.1 GO:0071546 pi-body(GO:0071546)
0.2 0.7 GO:0008275 gamma-tubulin small complex(GO:0008275)
0.2 0.5 GO:0071065 alpha9-beta1 integrin-vascular cell adhesion molecule-1 complex(GO:0071065)
0.1 0.5 GO:0070319 Golgi to plasma membrane transport vesicle(GO:0070319)
0.1 0.6 GO:1990071 TRAPPII protein complex(GO:1990071)
0.1 0.4 GO:0061673 mitotic spindle astral microtubule(GO:0061673)
0.1 0.4 GO:0044233 ER-mitochondrion membrane contact site(GO:0044233)
0.1 0.3 GO:0000110 nucleotide-excision repair factor 1 complex(GO:0000110)
0.1 0.3 GO:0043540 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase complex(GO:0043540)
0.1 0.4 GO:0035517 PR-DUB complex(GO:0035517)
0.1 0.3 GO:0070390 transcription export complex 2(GO:0070390)
0.1 0.2 GO:0036396 MIS complex(GO:0036396) mRNA editing complex(GO:0045293)
0.1 0.2 GO:0031085 BLOC-3 complex(GO:0031085)
0.1 0.3 GO:0032807 DNA ligase IV complex(GO:0032807)
0.1 0.2 GO:0005965 protein farnesyltransferase complex(GO:0005965)
0.1 0.4 GO:0072669 tRNA-splicing ligase complex(GO:0072669)
0.1 0.2 GO:0005655 nucleolar ribonuclease P complex(GO:0005655)
0.0 0.8 GO:0005903 brush border(GO:0005903)
0.0 0.6 GO:1990124 messenger ribonucleoprotein complex(GO:1990124)
0.0 0.6 GO:0070187 telosome(GO:0070187)
0.0 0.3 GO:0005952 cAMP-dependent protein kinase complex(GO:0005952)
0.0 0.6 GO:0002116 semaphorin receptor complex(GO:0002116)
0.0 0.5 GO:0035102 PRC1 complex(GO:0035102)
0.0 0.2 GO:0061617 MICOS complex(GO:0061617)
0.0 0.4 GO:0048188 Set1C/COMPASS complex(GO:0048188)
0.0 0.1 GO:0000221 vacuolar proton-transporting V-type ATPase, V1 domain(GO:0000221)
0.0 0.3 GO:0048179 activin receptor complex(GO:0048179)
0.0 0.2 GO:0097648 G-protein coupled receptor dimeric complex(GO:0038037) G-protein coupled receptor heterodimeric complex(GO:0038039) G-protein coupled receptor complex(GO:0097648)
0.0 0.9 GO:0031941 filamentous actin(GO:0031941)
0.0 0.4 GO:0031932 TORC2 complex(GO:0031932)
0.0 0.3 GO:0031209 SCAR complex(GO:0031209)
0.0 1.4 GO:0019005 SCF ubiquitin ligase complex(GO:0019005)
0.0 0.3 GO:0032039 integrator complex(GO:0032039)
0.0 0.4 GO:0030014 CCR4-NOT complex(GO:0030014)
0.0 0.3 GO:0080008 Cul4-RING E3 ubiquitin ligase complex(GO:0080008)
0.0 0.8 GO:0099634 postsynaptic density membrane(GO:0098839) postsynaptic specialization membrane(GO:0099634)
0.0 0.5 GO:0031105 septin ring(GO:0005940) septin complex(GO:0031105) septin cytoskeleton(GO:0032156)
0.0 0.1 GO:0071005 U2-type precatalytic spliceosome(GO:0071005)
0.0 1.0 GO:0030173 integral component of Golgi membrane(GO:0030173) intrinsic component of Golgi membrane(GO:0031228)
0.0 0.4 GO:0005844 polysome(GO:0005844)
0.0 0.4 GO:0031463 Cul3-RING ubiquitin ligase complex(GO:0031463)
0.0 0.6 GO:0098878 ionotropic glutamate receptor complex(GO:0008328) neurotransmitter receptor complex(GO:0098878)
0.0 0.4 GO:0016514 SWI/SNF complex(GO:0016514)
0.0 0.2 GO:0031083 BLOC-1 complex(GO:0031083)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.0 GO:0004031 aldehyde oxidase activity(GO:0004031) oxidoreductase activity, acting on the aldehyde or oxo group of donors, oxygen as acceptor(GO:0016623)
0.3 0.9 GO:0070336 flap-structured DNA binding(GO:0070336)
0.3 2.1 GO:0034584 piRNA binding(GO:0034584)
0.2 0.4 GO:0005547 phosphatidylinositol-3,4,5-trisphosphate binding(GO:0005547)
0.2 0.6 GO:0005176 ErbB-2 class receptor binding(GO:0005176)
0.2 1.4 GO:0010314 phosphatidylinositol-5-phosphate binding(GO:0010314)
0.2 0.5 GO:0032184 SUMO polymer binding(GO:0032184)
0.1 0.4 GO:0004736 pyruvate carboxylase activity(GO:0004736)
0.1 0.4 GO:0015462 protein-transmembrane transporting ATPase activity(GO:0015462) efflux transmembrane transporter activity(GO:0015562)
0.1 0.5 GO:0070513 death domain binding(GO:0070513)
0.1 0.4 GO:0033829 O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase activity(GO:0033829)
0.1 0.7 GO:0035173 histone kinase activity(GO:0035173)
0.1 0.3 GO:0030267 hydroxypyruvate reductase activity(GO:0016618) glyoxylate reductase (NADP) activity(GO:0030267)
0.1 0.4 GO:0042975 peroxisome proliferator activated receptor binding(GO:0042975)
0.1 0.9 GO:0000774 adenyl-nucleotide exchange factor activity(GO:0000774)
0.1 0.6 GO:0004430 1-phosphatidylinositol 4-kinase activity(GO:0004430)
0.1 0.3 GO:0008336 gamma-butyrobetaine dioxygenase activity(GO:0008336)
0.1 1.2 GO:0051864 histone demethylase activity (H3-K36 specific)(GO:0051864)
0.1 0.2 GO:0070259 tyrosyl-DNA phosphodiesterase activity(GO:0070259)
0.1 0.3 GO:0004534 5'-3' exoribonuclease activity(GO:0004534)
0.1 0.7 GO:0008172 S-methyltransferase activity(GO:0008172)
0.1 0.3 GO:0000014 single-stranded DNA endodeoxyribonuclease activity(GO:0000014)
0.1 0.7 GO:0035804 structural constituent of egg coat(GO:0035804)
0.1 0.4 GO:0030274 LIM domain binding(GO:0030274)
0.1 0.5 GO:0003834 beta-carotene 15,15'-monooxygenase activity(GO:0003834) carotenoid dioxygenase activity(GO:0010436)
0.1 0.2 GO:0004660 protein farnesyltransferase activity(GO:0004660)
0.1 0.3 GO:0009019 tRNA (guanine-N1-)-methyltransferase activity(GO:0009019)
0.0 0.2 GO:0016494 C-X-C chemokine receptor activity(GO:0016494)
0.0 0.5 GO:0015186 L-glutamine transmembrane transporter activity(GO:0015186)
0.0 0.6 GO:0031078 histone deacetylase activity (H3-K14 specific)(GO:0031078) NAD-dependent histone deacetylase activity (H3-K14 specific)(GO:0032041)
0.0 0.2 GO:1903924 estradiol binding(GO:1903924)
0.0 0.3 GO:0099530 G-protein coupled receptor activity involved in regulation of postsynaptic membrane potential(GO:0099530)
0.0 0.2 GO:0004726 non-membrane spanning protein tyrosine phosphatase activity(GO:0004726)
0.0 0.3 GO:0008603 cAMP-dependent protein kinase regulator activity(GO:0008603)
0.0 0.3 GO:0004457 lactate dehydrogenase activity(GO:0004457)
0.0 2.9 GO:0004715 non-membrane spanning protein tyrosine kinase activity(GO:0004715)
0.0 0.6 GO:0000900 translation repressor activity, nucleic acid binding(GO:0000900)
0.0 0.4 GO:0052795 exo-alpha-(2->3)-sialidase activity(GO:0052794) exo-alpha-(2->6)-sialidase activity(GO:0052795) exo-alpha-(2->8)-sialidase activity(GO:0052796)
0.0 0.7 GO:0051011 microtubule minus-end binding(GO:0051011)
0.0 0.6 GO:0008139 nuclear localization sequence binding(GO:0008139)
0.0 1.0 GO:0008195 phosphatidate phosphatase activity(GO:0008195)
0.0 0.3 GO:0071933 Arp2/3 complex binding(GO:0071933)
0.0 0.3 GO:0017116 single-stranded DNA-dependent ATP-dependent DNA helicase activity(GO:0017116) single-stranded DNA-dependent ATPase activity(GO:0043142)
0.0 0.2 GO:0004517 nitric-oxide synthase activity(GO:0004517)
0.0 0.2 GO:0004630 phospholipase D activity(GO:0004630)
0.0 0.2 GO:0070568 guanylyltransferase activity(GO:0070568)
0.0 0.6 GO:0003887 DNA-directed DNA polymerase activity(GO:0003887)
0.0 0.4 GO:0097199 cysteine-type endopeptidase activity involved in apoptotic signaling pathway(GO:0097199)
0.0 0.2 GO:0030332 cyclin binding(GO:0030332)
0.0 0.3 GO:0016783 sulfurtransferase activity(GO:0016783)
0.0 0.4 GO:0004535 poly(A)-specific ribonuclease activity(GO:0004535)
0.0 0.1 GO:0004060 arylamine N-acetyltransferase activity(GO:0004060)
0.0 0.5 GO:0042800 histone methyltransferase activity (H3-K4 specific)(GO:0042800)
0.0 0.1 GO:0042978 ornithine decarboxylase activator activity(GO:0042978)
0.0 0.3 GO:0003873 6-phosphofructo-2-kinase activity(GO:0003873)
0.0 0.2 GO:0004965 G-protein coupled GABA receptor activity(GO:0004965)
0.0 0.6 GO:0017154 semaphorin receptor activity(GO:0017154)
0.0 1.0 GO:0030898 actin-dependent ATPase activity(GO:0030898)
0.0 0.3 GO:0051721 protein phosphatase 2A binding(GO:0051721)
0.0 0.3 GO:0017002 activin-activated receptor activity(GO:0017002)
0.0 0.2 GO:0004526 ribonuclease P activity(GO:0004526)
0.0 0.5 GO:0043539 protein serine/threonine kinase activator activity(GO:0043539)
0.0 0.1 GO:0008332 low voltage-gated calcium channel activity(GO:0008332)
0.0 0.2 GO:0008429 phosphatidylethanolamine binding(GO:0008429)
0.0 0.4 GO:0004438 phosphatidylinositol-3-phosphatase activity(GO:0004438)
0.0 0.2 GO:1990841 promoter-specific chromatin binding(GO:1990841)
0.0 0.4 GO:0008574 ATP-dependent microtubule motor activity, plus-end-directed(GO:0008574)
0.0 0.7 GO:0018024 histone-lysine N-methyltransferase activity(GO:0018024)
0.0 0.2 GO:0015269 calcium-activated potassium channel activity(GO:0015269)
0.0 0.2 GO:0019894 kinesin binding(GO:0019894)
0.0 0.3 GO:0000030 mannosyltransferase activity(GO:0000030)
0.0 0.1 GO:0002039 p53 binding(GO:0002039)
0.0 0.6 GO:0015370 solute:sodium symporter activity(GO:0015370)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.7 PID HIV NEF PATHWAY HIV-1 Nef: Negative effector of Fas and TNF-alpha
0.0 0.6 PID RANBP2 PATHWAY Sumoylation by RanBP2 regulates transcriptional repression
0.0 0.8 PID DNA PK PATHWAY DNA-PK pathway in nonhomologous end joining
0.0 0.8 SA PTEN PATHWAY PTEN is a tumor suppressor that dephosphorylates the lipid messenger phosphatidylinositol triphosphate.
0.0 0.5 PID P38 MKK3 6PATHWAY p38 MAPK signaling pathway
0.0 0.1 ST TYPE I INTERFERON PATHWAY Type I Interferon (alpha/beta IFN) Pathway
0.0 0.2 SIG IL4RECEPTOR IN B LYPHOCYTES Genes related to IL4 rceptor signaling in B lymphocytes
0.0 0.9 PID FANCONI PATHWAY Fanconi anemia pathway
0.0 0.2 PID LPA4 PATHWAY LPA4-mediated signaling events
0.0 0.5 PID PRL SIGNALING EVENTS PATHWAY Signaling events mediated by PRL
0.0 0.4 PID KIT PATHWAY Signaling events mediated by Stem cell factor receptor (c-Kit)
0.0 0.2 PID INTEGRIN A4B1 PATHWAY Alpha4 beta1 integrin signaling events
0.0 0.4 PID ECADHERIN NASCENT AJ PATHWAY E-cadherin signaling in the nascent adherens junction
0.0 0.5 PID TGFBR PATHWAY TGF-beta receptor signaling
0.0 0.2 PID CERAMIDE PATHWAY Ceramide signaling pathway

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.7 REACTOME AMINE DERIVED HORMONES Genes involved in Amine-derived hormones
0.1 0.7 REACTOME RECRUITMENT OF NUMA TO MITOTIC CENTROSOMES Genes involved in Recruitment of NuMA to mitotic centrosomes
0.0 0.4 REACTOME ROLE OF DCC IN REGULATING APOPTOSIS Genes involved in Role of DCC in regulating apoptosis
0.0 0.4 REACTOME PKA MEDIATED PHOSPHORYLATION OF CREB Genes involved in PKA-mediated phosphorylation of CREB
0.0 0.4 REACTOME IONOTROPIC ACTIVITY OF KAINATE RECEPTORS Genes involved in Ionotropic activity of Kainate Receptors
0.0 0.4 REACTOME KINESINS Genes involved in Kinesins
0.0 0.4 REACTOME PRE NOTCH PROCESSING IN GOLGI Genes involved in Pre-NOTCH Processing in Golgi
0.0 0.3 REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS Genes involved in Cell-extracellular matrix interactions
0.0 0.2 REACTOME ENOS ACTIVATION AND REGULATION Genes involved in eNOS activation and regulation
0.0 0.4 REACTOME BASIGIN INTERACTIONS Genes involved in Basigin interactions
0.0 0.2 REACTOME CREATION OF C4 AND C2 ACTIVATORS Genes involved in Creation of C4 and C2 activators
0.0 0.9 REACTOME SIGNALING BY NOTCH1 Genes involved in Signaling by NOTCH1
0.0 0.3 REACTOME GLYCOLYSIS Genes involved in Glycolysis
0.0 0.3 REACTOME FORMATION OF INCISION COMPLEX IN GG NER Genes involved in Formation of incision complex in GG-NER
0.0 0.1 REACTOME REGULATION OF IFNA SIGNALING Genes involved in Regulation of IFNA signaling
0.0 0.4 REACTOME VOLTAGE GATED POTASSIUM CHANNELS Genes involved in Voltage gated Potassium channels