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PRJNA195909:zebrafish embryo and larva development

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Results for snai2

Z-value: 1.03

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Transcription factors associated with snai2

Gene Symbol Gene ID Gene Info
ENSDARG00000040046 snail family zinc finger 2

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
snai2dr11_v1_chr24_+_35387517_35387517-0.481.9e-01Click!

Activity profile of snai2 motif

Sorted Z-values of snai2 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr17_-_25331439 1.76 ENSDART00000155422
ENSDART00000082324
zona pellucida protein C
chr15_-_1590858 1.71 ENSDART00000081875
nanor
chr20_-_43743700 1.63 ENSDART00000100620
si:dkeyp-50f7.2
chr20_-_41992878 1.62 ENSDART00000100967
si:dkeyp-114g9.1
chr10_+_19596214 1.51 ENSDART00000183110

chr19_-_18313303 1.51 ENSDART00000164644
ENSDART00000167480
ENSDART00000163104
si:dkey-208k4.2
chr23_-_44574059 1.37 ENSDART00000123007
si:ch73-160p18.3
chr20_-_23426339 1.33 ENSDART00000004625
zygote arrest 1
chr17_-_2596125 1.23 ENSDART00000175740
zona pellucida glycoprotein 3, tandem duplicate 2
chr14_+_15155684 1.18 ENSDART00000167966
zgc:158852
chr21_-_43666420 1.10 ENSDART00000139008
ENSDART00000183996
ENSDART00000183395
si:dkey-229d11.3
si:dkey-229d11.5
chr17_-_25330775 1.08 ENSDART00000154048
zona pellucida protein C
chr3_+_1179601 0.98 ENSDART00000173378
TRIO and F-actin binding protein b
chr16_+_52343905 0.95 ENSDART00000131051
interferon lambda receptor 1
chr15_+_784149 0.93 ENSDART00000155114
zinc finger protein 970
chr7_-_51773166 0.92 ENSDART00000054591
bone morphogenetic protein 15
chr17_+_1360192 0.88 ENSDART00000184561
SIVA1, apoptosis-inducing factor
chr20_+_50052627 0.84 ENSDART00000188799
cleavage and polyadenylation specific factor 2
chr7_+_24528430 0.83 ENSDART00000133022
si:dkeyp-75h12.2
chr19_-_35439237 0.83 ENSDART00000145883
anillin, actin binding protein
chr1_+_53321878 0.80 ENSDART00000143909
TBC1 domain family, member 9 (with GRAM domain)
chr7_-_33868903 0.78 ENSDART00000173500
ENSDART00000178746
uveal autoantigen with coiled-coil domains and ankyrin repeats b
chr2_-_57469115 0.76 ENSDART00000192201
protein inhibitor of activated STAT, 4b
chr23_+_27779452 0.73 ENSDART00000134785
lysine (K)-specific methyltransferase 2D
chr7_-_53117131 0.73 ENSDART00000169211
ENSDART00000168890
ENSDART00000172179
ENSDART00000167882
cadherin 1, type 1, E-cadherin (epithelial)
chr23_+_6544453 0.72 ENSDART00000005373
SPO11 meiotic protein covalently bound to DSB
chr13_-_36525982 0.70 ENSDART00000114744
phosphofurin acidic cluster sorting protein 2
chr23_+_26026383 0.70 ENSDART00000141553
6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 1
chr22_-_38274188 0.69 ENSDART00000139420
ENSDART00000015117
ELAV like neuron-specific RNA binding protein 2
chr7_+_20917966 0.69 ENSDART00000129161
WD repeat containing, antisense to TP53
chr1_-_24349759 0.69 ENSDART00000142740
ENSDART00000177989
LPS-responsive vesicle trafficking, beach and anchor containing
chr23_+_27778670 0.68 ENSDART00000053863
lysine (K)-specific methyltransferase 2D
chr5_+_22974019 0.68 ENSDART00000147157
ENSDART00000020434
bromodomain and WD repeat domain containing 3
chr19_+_791538 0.67 ENSDART00000146554
ENSDART00000138406
transmembrane protein 79a
chr6_+_1724889 0.66 ENSDART00000157415
activin A receptor type 2Ab
chr23_+_2728095 0.64 ENSDART00000066086
zgc:114123
chr5_-_54712159 0.63 ENSDART00000149207
cyclin B1
chr1_+_24469313 0.63 ENSDART00000176581
family with sequence similarity 160, member A1a
chr20_-_43723860 0.63 ENSDART00000122051
Mix paired-like homeobox
chr5_+_6670945 0.62 ENSDART00000185686
paxillin a
chr17_+_24590177 0.61 ENSDART00000092941
rearranged L-myc fusion
chr14_-_26482096 0.61 ENSDART00000187280
SMAD family member 5
chr3_-_60027255 0.60 ENSDART00000189252
ENSDART00000154684
RecQ helicase-like 5
chr4_-_17263210 0.59 ENSDART00000147853
lymphoid-restricted membrane protein
chr12_-_7234915 0.57 ENSDART00000048866
inositol polyphosphate multikinase b
chr23_+_14771979 0.57 ENSDART00000137410
exosome component 10
chr13_+_2894536 0.57 ENSDART00000183678

chr7_+_74141297 0.56 ENSDART00000164992
RNA binding protein with multiple splicing
chr22_-_16758438 0.56 ENSDART00000132829
PATJ, crumbs cell polarity complex component
chr6_-_55399214 0.55 ENSDART00000168367
cathepsin A
chr5_-_57204352 0.55 ENSDART00000171252
ENSDART00000180727
mannosidase, alpha, class 2A, member 1
chr12_-_30359031 0.55 ENSDART00000192628
tudor domain containing 1
chr11_-_11791718 0.55 ENSDART00000180476
cell division cycle 6 homolog (S. cerevisiae)
chr4_+_72235562 0.53 ENSDART00000168547
si:cabz01071912.2
chr18_+_45666489 0.53 ENSDART00000180147
ENSDART00000151351
proline rich Gla (G-carboxyglutamic acid) 4 (transmembrane)
chr21_+_39197418 0.53 ENSDART00000076000
carboxypeptidase D, b
chr14_+_30285613 0.52 ENSDART00000173090
microtubule associated tumor suppressor 1a
chr21_-_21465111 0.51 ENSDART00000141487
nectin cell adhesion molecule 3b
chr8_-_3312384 0.50 ENSDART00000035965
fucosyltransferase 9b
chr15_+_20239141 0.50 ENSDART00000101152
ENSDART00000152473
serine peptidase inhibitor, Kunitz type, 2
chr12_-_4243268 0.50 ENSDART00000131275
zgc:92313
chr21_-_21515466 0.50 ENSDART00000147593
nectin cell adhesion molecule 3b
chr21_-_21178410 0.48 ENSDART00000185277
ENSDART00000141341
ENSDART00000145872
ENSDART00000079678
FtsJ RNA methyltransferase homolog 1
chr2_-_43851915 0.47 ENSDART00000146493
zinc finger E-box binding homeobox 1a
chr22_+_30195257 0.47 ENSDART00000027803
ENSDART00000172496
adducin 3 (gamma) a
chr5_+_18014931 0.46 ENSDART00000142562
activating signal cointegrator 1 complex subunit 2
chr11_-_25853212 0.46 ENSDART00000145655
transmembrane protein 51b
chr2_-_43852207 0.46 ENSDART00000192627
zinc finger E-box binding homeobox 1a
chr12_-_30358836 0.46 ENSDART00000152878
tudor domain containing 1
chr5_+_50913357 0.45 ENSDART00000092938
collagen, type IV, alpha 3 (Goodpasture antigen) binding protein a
chr18_-_26781616 0.45 ENSDART00000136776
ENSDART00000076484
KTI12 chromatin associated homolog
chr2_-_23677422 0.45 ENSDART00000079131
chromodomain protein, Y-like
chr18_-_38271298 0.44 ENSDART00000143016
cell cycle associated protein 1b
chr25_+_9027831 0.44 ENSDART00000155855
im:7145024
chr23_+_2560005 0.44 ENSDART00000186906
gamma-glutamyltransferase 7
chr10_+_37173029 0.44 ENSDART00000136510
kinase suppressor of ras 1a
chr12_-_2869565 0.43 ENSDART00000152772
zinc finger, DHHC-type containing 16b
chr17_-_49412313 0.43 ENSDART00000152100
methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1b
chr7_+_5975194 0.43 ENSDART00000123660
histone cluster 1 H2A family member 11
chr3_-_15080226 0.43 ENSDART00000109818
ENSDART00000139835
NME/NM23 nucleoside diphosphate kinase 4
chr20_-_33556983 0.43 ENSDART00000168798
rho-associated, coiled-coil containing protein kinase 2b, like
chr20_-_3238110 0.42 ENSDART00000008077
serine peptidase inhibitor, Kunitz type 1 b
chr2_-_58075414 0.42 ENSDART00000161920
nectin cell adhesion molecule 4
chr21_-_2958422 0.42 ENSDART00000174091
zgc:194215
chr21_+_39197628 0.42 ENSDART00000113607
carboxypeptidase D, b
chr9_-_28990649 0.42 ENSDART00000078823
protein tyrosine phosphatase, non-receptor type 4a
chr23_+_39963599 0.41 ENSDART00000166539
FYVE and coiled-coil domain containing 1a
chr17_-_11151655 0.41 ENSDART00000156383

chr21_-_2287589 0.41 ENSDART00000161554
si:ch73-299h12.4
chr18_+_13077800 0.40 ENSDART00000161153
gigaxonin
chr5_+_42259002 0.40 ENSDART00000083778
Era-like 12S mitochondrial rRNA chaperone 1
chr5_+_31049742 0.40 ENSDART00000173097
zinc finger, ZZ-type with EF hand domain 1
chr2_+_29257942 0.40 ENSDART00000184362
ENSDART00000025562
cadherin 18, type 2a
chr11_-_43473824 0.40 ENSDART00000179561
transmembrane protein 63Bb
chr22_+_9922301 0.39 ENSDART00000105924
bloody fingers
chr8_+_8196087 0.39 ENSDART00000026965
plexin B3
chr4_+_31456734 0.39 ENSDART00000140176
zinc finger protein 996
chr16_+_26747766 0.39 ENSDART00000183257
RAD54 homolog B (S. cerevisiae)
chr3_-_55511569 0.39 ENSDART00000108995
testis expressed 2
chr16_+_27444098 0.38 ENSDART00000157690
inversin
chr9_+_45428041 0.38 ENSDART00000193087
adenosine deaminase, RNA-specific, B1b
chr10_-_33588106 0.38 ENSDART00000155634
eva-1 homolog C (C. elegans)
chr14_+_989733 0.38 ENSDART00000161487
ENSDART00000127317
si:ch73-308l14.2
chr3_+_40255408 0.38 ENSDART00000074746
Smith-Magenis syndrome chromosome region, candidate 8a
chr22_-_26251563 0.38 ENSDART00000060888
ENSDART00000142821
coiled-coil domain containing 130
chr2_+_23677179 0.38 ENSDART00000153918
oxidative stress responsive 1a
chr2_+_26237322 0.38 ENSDART00000030520
paralemmin 1b
chr10_-_3416258 0.37 ENSDART00000005168
DEAD (Asp-Glu-Ala-Asp) box polypeptide 55
chr4_+_77993977 0.37 ENSDART00000174118
telomeric repeat binding factor a
chr4_+_26053044 0.37 ENSDART00000039877
si:ch211-244b2.1
chr14_-_21618005 0.37 ENSDART00000043162
receptor accessory protein 2
chr22_+_2657533 0.37 ENSDART00000034414
zgc:110821
chr3_+_15773991 0.36 ENSDART00000089923
zinc finger protein 652
chr1_+_56180416 0.36 ENSDART00000089358
crumbs homolog 3b
chr3_+_7040363 0.36 ENSDART00000157805

chr5_-_68244564 0.35 ENSDART00000169350

chr10_-_7472323 0.35 ENSDART00000163702
ENSDART00000167054
ENSDART00000167706
neuregulin 1
chr20_+_54336137 0.35 ENSDART00000113792
CLOCK-interacting pacemaker b
chr7_-_22632518 0.35 ENSDART00000161046
si:dkey-112a7.4
chr5_+_30596822 0.34 ENSDART00000188375
histone H4 transcription factor
chr22_+_7480465 0.34 ENSDART00000034545
zgc:92745
chr7_+_9041174 0.34 ENSDART00000163411

chr11_-_45470370 0.34 ENSDART00000173098
gem (nuclear organelle) associated protein 6
chr7_-_22632690 0.34 ENSDART00000165245
si:dkey-112a7.4
chr15_-_23761580 0.34 ENSDART00000137918
BCL2 binding component 3
chr4_-_4795205 0.32 ENSDART00000039313
zgc:162331
chr13_-_11800281 0.32 ENSDART00000079392
zmp:0000000662
chr5_+_431994 0.32 ENSDART00000181692
ENSDART00000170350
THAP domain containing, apoptosis associated protein 1
chr25_-_22889519 0.32 ENSDART00000128250
MOB kinase activator 2a
chr3_-_32362872 0.32 ENSDART00000035545
ENSDART00000012630
protein arginine methyltransferase 1
chr8_-_1698155 0.32 ENSDART00000186159

chr1_-_59313465 0.32 ENSDART00000158067
ENSDART00000159419
thioredoxin domain containing 11
chr4_-_2162688 0.32 ENSDART00000148900
potassium voltage-gated channel, Shaw-related subfamily, member 2
chr22_-_12304591 0.31 ENSDART00000136408
zinc finger, RAN-binding domain containing 3
chr22_+_22438783 0.31 ENSDART00000147825
kinesin family member 14
chr13_+_35955562 0.31 ENSDART00000137377
si:ch211-67f13.7
chr20_+_32756763 0.31 ENSDART00000023006
family with sequence similarity 84, member A
chr3_-_42016693 0.31 ENSDART00000184741
tweety family member 3a
chr10_-_33588310 0.31 ENSDART00000108658
eva-1 homolog C (C. elegans)
chr19_-_307246 0.31 ENSDART00000145916
leucine rich repeat and Ig domain containing 4a
chr3_-_30888415 0.31 ENSDART00000124458
lysine methyltransferase 5C
chr18_+_6641542 0.31 ENSDART00000160379
C2 calcium-dependent domain containing 5
chr10_-_94184 0.31 ENSDART00000146125
tetratricopeptide repeat domain 3
chr2_-_7605121 0.31 ENSDART00000182099

chr12_+_30705769 0.31 ENSDART00000186448
ENSDART00000066259
potassium channel, subfamily K, member 1a
chr2_+_19236969 0.30 ENSDART00000163875
ENSDART00000168644
coiled-coil and C2 domain containing 1B
chr5_-_38384289 0.30 ENSDART00000135260
misshapen-like kinase 1
chr19_+_4061699 0.30 ENSDART00000158309
ENSDART00000166512
bloodthirsty-related gene family, member 25
bloodthirsty-related gene family, member 26
chr20_+_36806398 0.30 ENSDART00000153317
ABRA C-terminal like
chr8_-_38022298 0.30 ENSDART00000067809
RAB11 family interacting protein 1 (class I) a
chr7_+_14005111 0.30 ENSDART00000187365
furin (paired basic amino acid cleaving enzyme) a
chr17_-_15777350 0.30 ENSDART00000155711
ankyrin repeat domain 6a
chr2_+_58877162 0.30 ENSDART00000122174

chr22_-_22231720 0.30 ENSDART00000160165
adaptor-related protein complex 3, delta 1 subunit
chr5_-_12031174 0.30 ENSDART00000159896
cytosolic arginine sensor for mTORC1 subunit 1
chr13_+_1381953 0.29 ENSDART00000019983
RAB23, member RAS oncogene family
chr7_-_19369002 0.29 ENSDART00000165680
netrin 4
chr21_-_35325466 0.29 ENSDART00000134780
ENSDART00000145930
ENSDART00000076715
ENSDART00000065341
ENSDART00000162189
ubiquitin-like domain containing CTD phosphatase 1
chr17_-_24575893 0.29 ENSDART00000141914
aftiphilin b
chr11_-_45429199 0.29 ENSDART00000173111
replication factor C (activator 1) 4
chr21_+_198269 0.29 ENSDART00000193485
ENSDART00000163696
gonadal somatic cell derived factor
chr24_-_31904924 0.29 ENSDART00000156060
ENSDART00000129741
ENSDART00000154276
si:ch73-78o10.1
chr10_-_44467384 0.29 ENSDART00000186382

chr3_+_37827373 0.29 ENSDART00000039517
acid-sensing (proton-gated) ion channel 2
chr19_+_4068134 0.29 ENSDART00000158285
bloodthirsty-related gene family, member 26
chr6_+_7555614 0.29 ENSDART00000187590
myosin, heavy chain 10, non-muscle
chr21_-_217589 0.28 ENSDART00000185017

chr9_+_45493341 0.28 ENSDART00000145616
adenosine deaminase, RNA-specific, B1b
chr24_+_36018164 0.28 ENSDART00000182815
ENSDART00000126941
guanine nucleotide binding protein (G protein), alpha activating activity polypeptide, olfactory type 2
chr25_+_32390794 0.28 ENSDART00000012600
galactokinase 2
chr4_-_74109792 0.28 ENSDART00000174320
zgc:154045
chr15_+_38221038 0.27 ENSDART00000188149
stromal interaction molecule 1a
chr15_-_434503 0.27 ENSDART00000122286

chr1_-_7673376 0.27 ENSDART00000013264
arginine and glutamate rich 1b
chr4_-_60312069 0.27 ENSDART00000167207
si:dkey-248e17.4
chr23_-_27607039 0.27 ENSDART00000183639
PHD finger protein 8
chr4_+_57505842 0.27 ENSDART00000127643

chr1_-_40341306 0.27 ENSDART00000190649
mastermind-like transcriptional coactivator 3
chr20_+_30797329 0.27 ENSDART00000145066
NHS-like 1b
chr12_+_30706158 0.26 ENSDART00000133869
potassium channel, subfamily K, member 1a
chr1_+_10019653 0.26 ENSDART00000190227
tripartite motif containing 2b
chr3_+_17456428 0.25 ENSDART00000090676
ENSDART00000182082
si:ch211-210g13.5
chr20_-_33583779 0.25 ENSDART00000097823
rho-associated, coiled-coil containing protein kinase 2b
chr7_-_8738827 0.25 ENSDART00000172807
ENSDART00000173026
si:ch211-1o7.3
chr16_+_33163858 0.25 ENSDART00000101943
Ras-related GTP binding Ca
chr5_-_32505109 0.25 ENSDART00000188219
N-terminal Xaa-Pro-Lys N-methyltransferase 1
chr10_+_5954787 0.25 ENSDART00000161887
ENSDART00000160345
ENSDART00000190046
mitogen-activated protein kinase kinase kinase 1, E3 ubiquitin protein ligase
chr15_+_38221196 0.25 ENSDART00000122134
ENSDART00000190099
stromal interaction molecule 1a
chr6_+_12482599 0.24 ENSDART00000090316
serine/threonine kinase 24b (STE20 homolog, yeast)
chr13_-_24669258 0.24 ENSDART00000000831
zinc finger protein 511
chr7_+_38090515 0.24 ENSDART00000131387
CCAAT/enhancer binding protein (C/EBP), gamma
chr9_-_28255029 0.24 ENSDART00000160387
cyclin Y-like 1
chr6_-_10728057 0.23 ENSDART00000002247
Sp3b transcription factor
chr10_-_108952 0.23 ENSDART00000127228
tetratricopeptide repeat domain 3
chr22_+_2417105 0.23 ENSDART00000106415
zgc:113220
chr16_+_41060161 0.23 ENSDART00000141130
SREBF chaperone
chr24_+_19578935 0.23 ENSDART00000137175
sulfatase 1
chr6_+_58289335 0.22 ENSDART00000177399
Ral GTPase activating protein, beta subunit (non-catalytic)
chr13_+_7578111 0.22 ENSDART00000175431
golgi brefeldin A resistant guanine nucleotide exchange factor 1
chr15_-_16177603 0.22 ENSDART00000156352
si:ch211-259g3.4

Network of associatons between targets according to the STRING database.

First level regulatory network of snai2

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 0.8 GO:1901223 negative regulation of NIK/NF-kappaB signaling(GO:1901223)
0.3 4.4 GO:0035803 binding of sperm to zona pellucida(GO:0007339) egg coat formation(GO:0035803) regulation of acrosome reaction(GO:0060046) positive regulation of acrosome reaction(GO:2000344)
0.2 0.9 GO:0060283 negative regulation of oocyte development(GO:0060283)
0.2 0.8 GO:0008356 asymmetric cell division(GO:0008356)
0.2 1.7 GO:0070586 cell-cell adhesion involved in gastrulation(GO:0070586)
0.2 0.6 GO:0035046 pronuclear migration(GO:0035046)
0.2 0.6 GO:0071034 CUT catabolic process(GO:0071034) CUT metabolic process(GO:0071043)
0.2 1.4 GO:0003422 growth plate cartilage morphogenesis(GO:0003422) chondrocyte intercalation involved in growth plate cartilage morphogenesis(GO:0003428)
0.1 1.0 GO:0045950 negative regulation of mitotic recombination(GO:0045950)
0.1 0.7 GO:0030576 nuclear body organization(GO:0030575) Cajal body organization(GO:0030576)
0.1 1.0 GO:1900026 positive regulation of substrate adhesion-dependent cell spreading(GO:1900026)
0.1 0.8 GO:0006398 mRNA 3'-end processing by stem-loop binding and cleavage(GO:0006398)
0.1 0.4 GO:0036135 activation of transmembrane receptor protein tyrosine kinase activity(GO:0007171) Schwann cell migration(GO:0036135) cardiac neuron differentiation(GO:0060945) cardiac neuron development(GO:0060959)
0.1 0.7 GO:0000706 meiotic DNA double-strand break processing(GO:0000706)
0.1 0.3 GO:0034773 histone H4-K20 methylation(GO:0034770) histone H4-K20 trimethylation(GO:0034773)
0.1 1.0 GO:0043046 DNA methylation involved in gamete generation(GO:0043046)
0.1 0.4 GO:0072003 kidney rudiment formation(GO:0072003) pronephros formation(GO:0072116)
0.1 0.6 GO:0006013 mannose metabolic process(GO:0006013)
0.1 0.3 GO:0061188 regulation of chromatin silencing at rDNA(GO:0061187) negative regulation of chromatin silencing at rDNA(GO:0061188)
0.1 0.4 GO:0042754 negative regulation of circadian rhythm(GO:0042754)
0.1 0.2 GO:0006480 N-terminal protein amino acid methylation(GO:0006480)
0.1 0.4 GO:1901098 positive regulation of autophagosome maturation(GO:1901098)
0.1 0.3 GO:0034969 histone arginine methylation(GO:0034969)
0.1 0.6 GO:0033206 meiotic cytokinesis(GO:0033206) polar body extrusion after meiotic divisions(GO:0040038)
0.1 0.5 GO:0032237 activation of store-operated calcium channel activity(GO:0032237) positive regulation of store-operated calcium channel activity(GO:1901341)
0.1 0.6 GO:0007080 mitotic metaphase plate congression(GO:0007080)
0.1 0.2 GO:0019284 L-methionine biosynthetic process from S-adenosylmethionine(GO:0019284)
0.1 0.5 GO:0033314 mitotic DNA replication checkpoint(GO:0033314)
0.1 0.3 GO:0090199 regulation of release of cytochrome c from mitochondria(GO:0090199) positive regulation of release of cytochrome c from mitochondria(GO:0090200)
0.1 0.3 GO:0010828 positive regulation of glucose transport(GO:0010828)
0.1 0.9 GO:0061055 myotome development(GO:0061055)
0.1 0.3 GO:0007191 adenylate cyclase-activating dopamine receptor signaling pathway(GO:0007191)
0.1 0.7 GO:0006382 adenosine to inosine editing(GO:0006382)
0.1 0.4 GO:0051673 membrane disruption in other organism(GO:0051673)
0.1 0.3 GO:0007221 positive regulation of transcription of Notch receptor target(GO:0007221)
0.0 0.2 GO:0010825 positive regulation of centrosome duplication(GO:0010825)
0.0 0.2 GO:0045737 positive regulation of cyclin-dependent protein serine/threonine kinase activity(GO:0045737) positive regulation of cyclin-dependent protein kinase activity(GO:1904031)
0.0 0.3 GO:0070650 actin filament bundle distribution(GO:0070650)
0.0 0.3 GO:0048478 replication fork protection(GO:0048478)
0.0 0.7 GO:0006003 fructose 2,6-bisphosphate metabolic process(GO:0006003)
0.0 0.3 GO:0006012 galactose metabolic process(GO:0006012)
0.0 0.6 GO:2000223 regulation of BMP signaling pathway involved in heart jogging(GO:2000223)
0.0 0.3 GO:0048490 anterograde synaptic vesicle transport(GO:0048490) synaptic vesicle cytoskeletal transport(GO:0099514) synaptic vesicle transport along microtubule(GO:0099517)
0.0 1.0 GO:0007286 spermatid development(GO:0007286)
0.0 0.1 GO:0006740 NADPH regeneration(GO:0006740)
0.0 0.4 GO:0071786 endoplasmic reticulum tubular network organization(GO:0071786)
0.0 0.2 GO:0000972 transcription-dependent tethering of RNA polymerase II gene DNA at nuclear periphery(GO:0000972)
0.0 0.6 GO:0032958 inositol phosphate biosynthetic process(GO:0032958)
0.0 0.3 GO:0060971 embryonic heart tube left/right pattern formation(GO:0060971)
0.0 0.4 GO:0006228 UTP biosynthetic process(GO:0006228) UTP metabolic process(GO:0046051)
0.0 0.8 GO:0016925 protein sumoylation(GO:0016925)
0.0 0.1 GO:0043011 myeloid dendritic cell activation(GO:0001773) myeloid dendritic cell differentiation(GO:0043011)
0.0 0.1 GO:0060406 copulation(GO:0007620) regulation of epinephrine secretion(GO:0014060) positive regulation of epinephrine secretion(GO:0032812) positive regulation of catecholamine secretion(GO:0033605) penile erection(GO:0043084) epinephrine transport(GO:0048241) epinephrine secretion(GO:0048242) regulation of penile erection(GO:0060405) positive regulation of penile erection(GO:0060406) prolactin secretion(GO:0070459)
0.0 0.2 GO:0032793 positive regulation of CREB transcription factor activity(GO:0032793)
0.0 0.1 GO:0046689 response to mercury ion(GO:0046689) detoxification of mercury ion(GO:0050787)
0.0 0.6 GO:0030322 stabilization of membrane potential(GO:0030322)
0.0 0.3 GO:0001556 oocyte maturation(GO:0001556)
0.0 0.3 GO:1904262 negative regulation of TORC1 signaling(GO:1904262)
0.0 0.5 GO:0002098 tRNA wobble uridine modification(GO:0002098)
0.0 0.2 GO:0043981 histone H4-K5 acetylation(GO:0043981) histone H4-K8 acetylation(GO:0043982)
0.0 0.3 GO:0007340 acrosome reaction(GO:0007340)
0.0 0.1 GO:0021797 forebrain anterior/posterior pattern specification(GO:0021797)
0.0 0.1 GO:0098815 postsynaptic density assembly(GO:0097107) modulation of excitatory postsynaptic potential(GO:0098815) positive regulation of excitatory postsynaptic potential(GO:2000463)
0.0 0.1 GO:0006537 glutamate biosynthetic process(GO:0006537) glutamine catabolic process(GO:0006543)
0.0 0.4 GO:0000028 ribosomal small subunit assembly(GO:0000028)
0.0 0.2 GO:0099558 maintenance of presynaptic active zone structure(GO:0048790) maintenance of synapse structure(GO:0099558)
0.0 1.7 GO:0017148 negative regulation of translation(GO:0017148)
0.0 0.5 GO:0030488 tRNA methylation(GO:0030488)
0.0 0.3 GO:0097475 motor neuron migration(GO:0097475)
0.0 0.2 GO:0071230 cellular response to amino acid stimulus(GO:0071230)
0.0 0.6 GO:0001706 endoderm formation(GO:0001706)
0.0 0.7 GO:0032924 activin receptor signaling pathway(GO:0032924)
0.0 0.2 GO:2000601 positive regulation of actin nucleation(GO:0051127) positive regulation of Arp2/3 complex-mediated actin nucleation(GO:2000601)
0.0 0.2 GO:0032933 response to sterol depletion(GO:0006991) SREBP signaling pathway(GO:0032933) cellular response to sterol depletion(GO:0071501)
0.0 0.1 GO:0006102 isocitrate metabolic process(GO:0006102)
0.0 0.3 GO:0060287 epithelial cilium movement involved in determination of left/right asymmetry(GO:0060287)
0.0 0.3 GO:0000387 spliceosomal snRNP assembly(GO:0000387)
0.0 0.3 GO:0035469 determination of pancreatic left/right asymmetry(GO:0035469) determination of liver left/right asymmetry(GO:0071910)
0.0 0.5 GO:0051016 barbed-end actin filament capping(GO:0051016)
0.0 0.5 GO:0007131 reciprocal meiotic recombination(GO:0007131)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.6 GO:0097125 cyclin B1-CDK1 complex(GO:0097125)
0.2 0.7 GO:0043540 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase complex(GO:0043540)
0.1 1.0 GO:0071546 pi-body(GO:0071546)
0.1 0.8 GO:0005826 actomyosin contractile ring(GO:0005826)
0.1 1.4 GO:0044666 MLL3/4 complex(GO:0044666)
0.1 0.8 GO:0097431 mitotic spindle pole(GO:0097431)
0.1 0.8 GO:0005847 mRNA cleavage and polyadenylation specificity factor complex(GO:0005847)
0.1 0.6 GO:0000176 nuclear exosome (RNase complex)(GO:0000176)
0.0 0.2 GO:1990131 EGO complex(GO:0034448) Gtr1-Gtr2 GTPase complex(GO:1990131)
0.0 1.0 GO:0032588 trans-Golgi network membrane(GO:0032588)
0.0 0.7 GO:0048179 activin receptor complex(GO:0048179)
0.0 0.5 GO:0033588 Elongator holoenzyme complex(GO:0033588)
0.0 0.3 GO:0032797 SMN complex(GO:0032797)
0.0 0.4 GO:0032045 guanyl-nucleotide exchange factor complex(GO:0032045)
0.0 0.3 GO:0005663 DNA replication factor C complex(GO:0005663)
0.0 0.7 GO:0015030 Cajal body(GO:0015030)
0.0 0.7 GO:0030057 desmosome(GO:0030057)
0.0 0.3 GO:0061700 GATOR2 complex(GO:0061700)
0.0 0.6 GO:0071144 SMAD2-SMAD3 protein complex(GO:0071144)
0.0 0.4 GO:0098827 endoplasmic reticulum tubular network(GO:0071782) endoplasmic reticulum subcompartment(GO:0098827)
0.0 0.4 GO:0071014 post-mRNA release spliceosomal complex(GO:0071014)
0.0 0.4 GO:0070187 telosome(GO:0070187)
0.0 0.3 GO:0032809 neuronal cell body membrane(GO:0032809) cell body membrane(GO:0044298)
0.0 0.1 GO:0001650 fibrillar center(GO:0001650)
0.0 0.2 GO:0005956 protein kinase CK2 complex(GO:0005956)
0.0 0.5 GO:0043204 perikaryon(GO:0043204)
0.0 0.3 GO:0043195 terminal bouton(GO:0043195)
0.0 0.7 GO:0005776 autophagosome(GO:0005776)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 4.1 GO:0035804 structural constituent of egg coat(GO:0035804)
0.2 0.6 GO:0008440 inositol-1,4,5-trisphosphate 3-kinase activity(GO:0008440)
0.1 0.9 GO:0070698 type I activin receptor binding(GO:0070698)
0.1 1.0 GO:0034584 piRNA binding(GO:0034584)
0.1 0.7 GO:0010858 calcium-dependent protein kinase inhibitor activity(GO:0008427) calcium-dependent protein kinase regulator activity(GO:0010858)
0.1 0.6 GO:0004185 serine-type carboxypeptidase activity(GO:0004185)
0.1 0.3 GO:0042799 histone methyltransferase activity (H4-K20 specific)(GO:0042799)
0.1 0.3 GO:0034618 arginine binding(GO:0034618)
0.1 0.2 GO:0071885 N-terminal protein N-methyltransferase activity(GO:0071885)
0.1 0.7 GO:0016889 endodeoxyribonuclease activity, producing 3'-phosphomonoesters(GO:0016889)
0.1 1.6 GO:0042800 histone methyltransferase activity (H3-K4 specific)(GO:0042800)
0.1 0.3 GO:0035575 histone demethylase activity (H4-K20 specific)(GO:0035575)
0.1 0.6 GO:0009378 four-way junction helicase activity(GO:0009378)
0.1 0.4 GO:0015616 DNA translocase activity(GO:0015616)
0.1 0.7 GO:0003726 double-stranded RNA adenosine deaminase activity(GO:0003726)
0.1 0.8 GO:0061665 SUMO ligase activity(GO:0061665)
0.1 0.7 GO:0001965 G-protein alpha-subunit binding(GO:0001965)
0.1 0.3 GO:0032190 acrosin binding(GO:0032190)
0.0 0.7 GO:0003873 6-phosphofructo-2-kinase activity(GO:0003873)
0.0 0.4 GO:0098505 G-rich strand telomeric DNA binding(GO:0098505)
0.0 0.7 GO:0017002 activin-activated receptor activity(GO:0017002)
0.0 0.6 GO:0015271 outward rectifier potassium channel activity(GO:0015271)
0.0 0.1 GO:0016422 mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity(GO:0016422)
0.0 0.6 GO:0004559 alpha-mannosidase activity(GO:0004559)
0.0 0.3 GO:0072320 volume-sensitive chloride channel activity(GO:0072320)
0.0 0.9 GO:0004181 metallocarboxypeptidase activity(GO:0004181)
0.0 0.4 GO:0043024 ribosomal small subunit binding(GO:0043024)
0.0 0.1 GO:0016652 NAD(P)+ transhydrogenase activity(GO:0008746) oxidoreductase activity, acting on NAD(P)H, NAD(P) as acceptor(GO:0016652)
0.0 0.4 GO:0030296 protein tyrosine kinase activator activity(GO:0030296)
0.0 0.3 GO:0072518 Rho-dependent protein serine/threonine kinase activity(GO:0072518)
0.0 0.6 GO:0070411 I-SMAD binding(GO:0070411)
0.0 0.3 GO:0003689 DNA clamp loader activity(GO:0003689) protein-DNA loading ATPase activity(GO:0033170)
0.0 0.2 GO:0008140 cAMP response element binding protein binding(GO:0008140)
0.0 0.1 GO:0046592 polyamine oxidase activity(GO:0046592)
0.0 0.3 GO:0015280 ligand-gated sodium channel activity(GO:0015280)
0.0 0.5 GO:0003688 DNA replication origin binding(GO:0003688)
0.0 0.1 GO:0004449 isocitrate dehydrogenase (NAD+) activity(GO:0004449)
0.0 0.2 GO:0003854 3-beta-hydroxy-delta5-steroid dehydrogenase activity(GO:0003854)
0.0 0.5 GO:0005246 calcium channel regulator activity(GO:0005246)
0.0 0.3 GO:0016274 arginine N-methyltransferase activity(GO:0016273) protein-arginine N-methyltransferase activity(GO:0016274)
0.0 0.9 GO:0032813 tumor necrosis factor receptor superfamily binding(GO:0032813)
0.0 0.1 GO:0030160 GKAP/Homer scaffold activity(GO:0030160)
0.0 0.6 GO:0000175 3'-5'-exoribonuclease activity(GO:0000175)
0.0 0.2 GO:0047676 arachidonate-CoA ligase activity(GO:0047676)
0.0 0.1 GO:0004362 glutathione-disulfide reductase activity(GO:0004362)
0.0 0.1 GO:0016922 ligand-dependent nuclear receptor binding(GO:0016922)
0.0 0.3 GO:0004298 threonine-type endopeptidase activity(GO:0004298) threonine-type peptidase activity(GO:0070003)
0.0 0.1 GO:0004359 glutaminase activity(GO:0004359)
0.0 0.1 GO:0035613 RNA stem-loop binding(GO:0035613)
0.0 0.2 GO:0016861 intramolecular oxidoreductase activity, interconverting aldoses and ketoses(GO:0016861)
0.0 0.4 GO:0004550 nucleoside diphosphate kinase activity(GO:0004550)
0.0 0.9 GO:0016538 cyclin-dependent protein serine/threonine kinase regulator activity(GO:0016538)
0.0 0.5 GO:0008175 tRNA methyltransferase activity(GO:0008175)
0.0 0.3 GO:0005154 epidermal growth factor receptor binding(GO:0005154)
0.0 0.2 GO:0001102 RNA polymerase II activating transcription factor binding(GO:0001102)
0.0 0.7 GO:0044325 ion channel binding(GO:0044325)
0.0 0.1 GO:0010314 phosphatidylinositol-5-phosphate binding(GO:0010314)
0.0 0.1 GO:0015129 lactate transmembrane transporter activity(GO:0015129)
0.0 0.3 GO:0019200 carbohydrate kinase activity(GO:0019200)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.6 PID ALK2 PATHWAY ALK2 signaling events
0.0 0.4 PID ERBB NETWORK PATHWAY ErbB receptor signaling network
0.0 0.2 PID TCR JNK PATHWAY JNK signaling in the CD4+ TCR pathway
0.0 0.7 PID ECADHERIN KERATINOCYTE PATHWAY E-cadherin signaling in keratinocytes
0.0 0.8 PID ATR PATHWAY ATR signaling pathway
0.0 0.6 PID FOXM1 PATHWAY FOXM1 transcription factor network
0.0 0.2 PID NFKAPPAB ATYPICAL PATHWAY Atypical NF-kappaB pathway
0.0 0.2 SA CASPASE CASCADE Apoptosis is mediated by caspases, cysteine proteases arranged in a proteolytic cascade.
0.0 0.2 PID ARF 3PATHWAY Arf1 pathway
0.0 0.2 PID IFNG PATHWAY IFN-gamma pathway
0.0 0.1 PID NEPHRIN NEPH1 PATHWAY Nephrin/Neph1 signaling in the kidney podocyte

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.7 REACTOME APOPTOTIC CLEAVAGE OF CELL ADHESION PROTEINS Genes involved in Apoptotic cleavage of cell adhesion proteins
0.1 0.6 REACTOME RECRUITMENT OF NUMA TO MITOTIC CENTROSOMES Genes involved in Recruitment of NuMA to mitotic centrosomes
0.0 0.6 REACTOME SIGNALING BY BMP Genes involved in Signaling by BMP
0.0 0.4 REACTOME DOWNREGULATION OF ERBB2 ERBB3 SIGNALING Genes involved in Downregulation of ERBB2:ERBB3 signaling
0.0 0.8 REACTOME PROCESSING OF INTRONLESS PRE MRNAS Genes involved in Processing of Intronless Pre-mRNAs
0.0 0.3 REACTOME ACTIVATION OF BH3 ONLY PROTEINS Genes involved in Activation of BH3-only proteins
0.0 0.5 REACTOME ASSOCIATION OF LICENSING FACTORS WITH THE PRE REPLICATIVE COMPLEX Genes involved in Association of licensing factors with the pre-replicative complex
0.0 0.1 REACTOME TGF BETA RECEPTOR SIGNALING IN EMT EPITHELIAL TO MESENCHYMAL TRANSITION Genes involved in TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)
0.0 0.7 REACTOME GLYCOLYSIS Genes involved in Glycolysis
0.0 0.4 REACTOME GLUTATHIONE CONJUGATION Genes involved in Glutathione conjugation
0.0 1.0 REACTOME EXTENSION OF TELOMERES Genes involved in Extension of Telomeres
0.0 0.5 REACTOME SYNTHESIS AND INTERCONVERSION OF NUCLEOTIDE DI AND TRIPHOSPHATES Genes involved in Synthesis and interconversion of nucleotide di- and triphosphates
0.0 0.3 REACTOME NOTCH HLH TRANSCRIPTION PATHWAY Genes involved in Notch-HLH transcription pathway
0.0 0.2 REACTOME COPI MEDIATED TRANSPORT Genes involved in COPI Mediated Transport
0.0 0.6 REACTOME N GLYCAN ANTENNAE ELONGATION IN THE MEDIAL TRANS GOLGI Genes involved in N-glycan antennae elongation in the medial/trans-Golgi
0.0 0.8 REACTOME MEIOTIC RECOMBINATION Genes involved in Meiotic Recombination
0.0 0.3 REACTOME SEMA4D INDUCED CELL MIGRATION AND GROWTH CONE COLLAPSE Genes involved in Sema4D induced cell migration and growth-cone collapse
0.0 0.2 REACTOME ROLE OF DCC IN REGULATING APOPTOSIS Genes involved in Role of DCC in regulating apoptosis
0.0 0.3 REACTOME OTHER SEMAPHORIN INTERACTIONS Genes involved in Other semaphorin interactions
0.0 0.6 REACTOME GLYCOSPHINGOLIPID METABOLISM Genes involved in Glycosphingolipid metabolism
0.0 0.2 REACTOME METABOLISM OF POLYAMINES Genes involved in Metabolism of polyamines
0.0 0.3 REACTOME SMAD2 SMAD3 SMAD4 HETEROTRIMER REGULATES TRANSCRIPTION Genes involved in SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription