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PRJNA195909:zebrafish embryo and larva development

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Results for si:dkey-43p13.5+uncx

Z-value: 0.72

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Transcription factors associated with si:dkey-43p13.5+uncx

Gene Symbol Gene ID Gene Info
ENSDARG00000102976 UNC homeobox
ENSDARG00000104199 si_dkey-43p13.5

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
si:dkey-43p13.5dr11_v1_chr3_+_43086548_430865480.771.5e-02Click!
uncxdr11_v1_chr3_-_43356082_43356082-0.353.5e-01Click!

Activity profile of si:dkey-43p13.5+uncx motif

Sorted Z-values of si:dkey-43p13.5+uncx motif

Promoter Log-likelihood Transcript Gene Gene Info
chr21_+_25777425 2.02 ENSDART00000021620
claudin d
chr11_-_6452444 1.34 ENSDART00000137879
ENSDART00000134957
ENSDART00000004483
La ribonucleoprotein domain family, member 6b
chr10_-_34916208 1.30 ENSDART00000187371
cyclin A1
chr24_+_12835935 1.20 ENSDART00000114762
nanog homeobox
chr8_+_45334255 1.18 ENSDART00000126848
ENSDART00000134161
ENSDART00000142322
ENSDART00000145011
ENSDART00000183560
poly(A) binding protein, cytoplasmic 1-like
chr10_-_34915886 1.08 ENSDART00000141201
ENSDART00000002166
cyclin A1
chr1_-_18811517 1.07 ENSDART00000142026
si:dkey-167i21.2
chr12_-_14143344 1.06 ENSDART00000152742
bucky ball 2-like
chr18_-_40708537 1.06 ENSDART00000077577
si:ch211-132b12.8
chr10_-_21362071 1.01 ENSDART00000125167
avidin
chr10_+_6884627 0.98 ENSDART00000125262
ENSDART00000121729
ENSDART00000105384
DEAD (Asp-Glu-Ala-Asp) box polypeptide 4
chr10_-_21362320 0.97 ENSDART00000189789
avidin
chr9_+_8396755 0.94 ENSDART00000043067
zgc:171776
chr7_-_51773166 0.94 ENSDART00000054591
bone morphogenetic protein 15
chr1_-_55248496 0.92 ENSDART00000098615
nanos homolog 3
chr22_+_17828267 0.85 ENSDART00000136016
hyaluronan and proteoglycan link protein 4
chr18_+_20560616 0.77 ENSDART00000136710
ENSDART00000151974
ENSDART00000121699
ENSDART00000040074
WEE1 homolog 2 (S. pombe)
chr10_-_25217347 0.77 ENSDART00000036906
karyopherin alpha 7 (importin alpha 8)
chr1_-_33645967 0.77 ENSDART00000192758
claudin g
chr11_+_18183220 0.77 ENSDART00000113468

chr20_-_23426339 0.76 ENSDART00000004625
zygote arrest 1
chr22_-_20695237 0.75 ENSDART00000112722
oogenesis-related gene
chr24_-_9997948 0.71 ENSDART00000136274
si:ch211-146l10.7
chr14_-_33481428 0.71 ENSDART00000147059
ENSDART00000140001
ENSDART00000124242
ENSDART00000164836
ENSDART00000190104
ENSDART00000186833
ENSDART00000180873
lysosomal-associated membrane protein 2
chr2_+_6253246 0.67 ENSDART00000058256
ENSDART00000076700
zona pellucida glycoprotein 3b
chr10_-_8053753 0.66 ENSDART00000162289
si:ch211-251f6.7
chr20_-_6532462 0.64 ENSDART00000054653
MCM3 minichromosome maintenance deficient 3 (S. cerevisiae), like
chr5_+_6954162 0.63 ENSDART00000086666
sperm-tail PG-rich repeat containing 2
chr17_-_4245902 0.63 ENSDART00000151851
growth differentiation factor 3
chr2_-_17115256 0.63 ENSDART00000190488
PIF1 5'-to-3' DNA helicase homolog (S. cerevisiae)
chr24_-_2450597 0.62 ENSDART00000188080
ENSDART00000093331
ras responsive element binding protein 1a
chr7_+_24528430 0.61 ENSDART00000133022
si:dkeyp-75h12.2
chr1_+_35985813 0.60 ENSDART00000179634
ENSDART00000139636
ENSDART00000175902
zgc:152968
chr22_+_4488454 0.60 ENSDART00000170620
cortexin 1
chr14_-_8940499 0.58 ENSDART00000129030
zgc:153681
chr11_+_35171406 0.58 ENSDART00000110839
MON1 secretory trafficking family member A
chr5_-_15283509 0.58 ENSDART00000052712
guanine nucleotide binding protein (G protein), beta polypeptide 1-like
chr4_+_9467049 0.57 ENSDART00000012659
zgc:55888
chr4_+_11723852 0.57 ENSDART00000028820
muskelin 1, intracellular mediator containing kelch motifs
chr23_-_31913069 0.56 ENSDART00000135526
mitochondrial fission regulator 2
chr23_+_28322986 0.55 ENSDART00000134710
baculoviral IAP repeat containing 5b
chr11_-_44801968 0.55 ENSDART00000161846
microtubule-associated protein 1 light chain 3 gamma
chr9_+_29548630 0.55 ENSDART00000132295
ring finger protein 17
chr5_-_68333081 0.54 ENSDART00000168786
linker histone H1M
chr24_+_1023839 0.54 ENSDART00000082526
zgc:111976
chr1_-_17693273 0.53 ENSDART00000146258
cilia and flagella associated protein 97
chr13_+_33462232 0.53 ENSDART00000177841
zgc:136302
chr11_+_18175893 0.53 ENSDART00000177625
zgc:173545
chr16_+_29509133 0.53 ENSDART00000112116
cathepsin S, ortholog2, tandem duplicate 1
chr2_-_38287987 0.53 ENSDART00000185329
ENSDART00000061677
si:ch211-14a17.6
chr20_-_20324792 0.52 ENSDART00000042376
small nuclear RNA activating complex, polypeptide 1a
chr16_-_29387215 0.52 ENSDART00000148787
S100 calcium binding protein A1
chr16_+_47207691 0.52 ENSDART00000062507
islet cell autoantigen 1
chr16_-_42056137 0.51 ENSDART00000102798
zona pellucida glycoprotein 3d tandem duplicate 2
chr19_-_29887629 0.50 ENSDART00000066123
karyopherin alpha 6 (importin alpha 7)
chr20_-_34028967 0.50 ENSDART00000153408
ENSDART00000033817
SCY1-like, kinase-like 3
chr3_+_7808459 0.50 ENSDART00000162374
hook microtubule-tethering protein 2
chr13_-_31008275 0.50 ENSDART00000139394
WDFY family member 4
chr11_+_44804685 0.50 ENSDART00000163660
striatin, calmodulin binding protein
chr11_-_1550709 0.49 ENSDART00000110097
si:ch73-303b9.1
chr25_+_5972690 0.48 ENSDART00000067517
si:ch211-11i22.4
chr16_-_54919260 0.48 ENSDART00000156533
keratinocyte differentiation factor 1a
chr5_-_68779747 0.48 ENSDART00000192636
ENSDART00000188039
methylphosphate capping enzyme
chr9_+_29548195 0.48 ENSDART00000176057
ring finger protein 17
chr9_+_22656976 0.47 ENSDART00000136249
ENSDART00000139270
si:dkey-189g17.2
chr8_-_1838315 0.47 ENSDART00000114476
ENSDART00000140077
phosphatidylinositol 4-kinase, catalytic, alpha b
chr2_-_26596794 0.47 ENSDART00000134685
ENSDART00000056787
zgc:113691
chr10_+_15024772 0.47 ENSDART00000135667
si:dkey-88l16.5
chr25_+_5604512 0.47 ENSDART00000042781
plexin b2b
chr22_+_17261801 0.46 ENSDART00000192978
ENSDART00000193187
ENSDART00000179953
ENSDART00000134798
tudor domain containing 5
chr15_-_34408777 0.46 ENSDART00000139934
alkylglycerol monooxygenase
chr1_+_21937201 0.46 ENSDART00000087729
lysine (K)-specific demethylase 4C
chr3_-_25268751 0.45 ENSDART00000139423
mannosyl (beta-1,4-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase a
chr20_-_45060241 0.45 ENSDART00000185227
kelch-like family member 29
chr19_+_2631565 0.45 ENSDART00000171487
family with sequence similarity 126, member A
chr6_-_43283122 0.44 ENSDART00000186022
FERM domain containing 4Ba
chr7_+_22313533 0.44 ENSDART00000123457
si:dkey-11f12.2
chr14_+_34492288 0.44 ENSDART00000144301
wingless-type MMTV integration site family, member 8a
chr20_+_13883131 0.43 ENSDART00000003248
ENSDART00000152611
NIMA-related kinase 2
chr9_+_45428041 0.43 ENSDART00000193087
adenosine deaminase, RNA-specific, B1b
chr22_-_17653143 0.43 ENSDART00000089171
histocompatibility (minor) HA-1 b
chr23_+_42254960 0.43 ENSDART00000102980
zinc finger, CCHC domain containing 11
chr16_+_42471455 0.43 ENSDART00000166640
si:ch211-215k15.5
chr23_+_19590006 0.43 ENSDART00000021231
sarcolemma associated protein b
chr13_-_4018888 0.42 ENSDART00000058238
tight junction associated protein 1 (peripheral)
chr20_-_51831657 0.42 ENSDART00000165076
melanoma inhibitory activity family, member 3
chr20_-_14114078 0.41 ENSDART00000168434
ENSDART00000104032
si:ch211-223m11.2
chr13_-_31017960 0.41 ENSDART00000145287
WDFY family member 4
chr13_-_35808904 0.41 ENSDART00000171667
mitogen-activated protein kinase kinase kinase 4
chr23_+_24272421 0.41 ENSDART00000029974
chloride channel K
chr5_-_9216758 0.41 ENSDART00000134896
ENSDART00000147000
low-density lipoprotein receptor related-protein 13
chr23_-_31913231 0.41 ENSDART00000146852
ENSDART00000085054
mitochondrial fission regulator 2
chr24_+_34069675 0.40 ENSDART00000143995
si:ch211-190p8.2
chr12_-_30359498 0.40 ENSDART00000152981
ENSDART00000189988
tudor domain containing 1
chr20_-_19511700 0.40 ENSDART00000040191
sorting nexin 17
chr5_+_66433287 0.40 ENSDART00000170757
kinetochore associated 1
chr15_-_16177603 0.40 ENSDART00000156352
si:ch211-259g3.4
chr5_-_11809710 0.40 ENSDART00000186998
ENSDART00000181363
ENSDART00000180681
neurofibromin 2a (merlin)
chr12_-_30359031 0.40 ENSDART00000192628
tudor domain containing 1
chr13_+_40501455 0.40 ENSDART00000114985
heparanase 2
chr18_+_39487486 0.40 ENSDART00000126978
acyl-CoA dehydrogenase long chain
chr3_-_61494840 0.39 ENSDART00000101957
BAI1-associated protein 2-like 1b
chr10_-_32494499 0.39 ENSDART00000129395
UV radiation resistance associated gene
chr25_-_1323623 0.39 ENSDART00000156532
ENSDART00000157163
ENSDART00000156062
ENSDART00000082447
ENSDART00000189175
calmodulin-like 4b
chr22_-_22147375 0.39 ENSDART00000149304
cell division cycle 34 homolog (S. cerevisiae) a
chr8_-_20230559 0.39 ENSDART00000193677
MLLT1, super elongation complex subunit a
chr14_+_35428152 0.39 ENSDART00000172597
synaptotagmin-like 4
chr14_+_26247319 0.39 ENSDART00000192793
coiled-coil domain containing 69
chr22_+_1170294 0.38 ENSDART00000159761
ENSDART00000169809
interferon regulatory factor 6
chr8_+_11425048 0.38 ENSDART00000018739
tight junction protein 2b (zona occludens 2)
chr21_-_36453594 0.38 ENSDART00000193176
CCR4-NOT transcription complex, subunit 8
chr4_+_25917915 0.38 ENSDART00000138603
vezatin, adherens junctions transmembrane protein
chr12_-_30358836 0.38 ENSDART00000152878
tudor domain containing 1
chr22_-_10055744 0.38 ENSDART00000143686
si:ch211-222k6.2
chr6_-_2133737 0.38 ENSDART00000158535
V-set and transmembrane domain containing 2 like
chr14_+_31496543 0.38 ENSDART00000170683
PHD finger protein 6
chr6_-_2134581 0.38 ENSDART00000175478
V-set and transmembrane domain containing 2 like
chr11_-_40457325 0.38 ENSDART00000128442
tumor necrosis factor receptor superfamily, member 1B
chr9_-_14683574 0.38 ENSDART00000144022
par-3 family cell polarity regulator beta b
chr19_+_40069524 0.38 ENSDART00000151365
ENSDART00000140926
zinc finger, MYM-type 4
chr22_-_20924564 0.38 ENSDART00000100642
ENSDART00000032770
elongation factor RNA polymerase II
chr12_+_1609563 0.38 ENSDART00000163559
solute carrier family 39 member 11
chr8_-_22326744 0.37 ENSDART00000137645
centrosomal protein 104
chr19_-_5103141 0.37 ENSDART00000150952
triosephosphate isomerase 1a
chr10_+_15255198 0.37 ENSDART00000139047
ENSDART00000172107
ENSDART00000183413
ENSDART00000185314
very low density lipoprotein receptor
chr8_+_50190742 0.36 ENSDART00000099863
solute carrier family 25 (mitochondrial iron transporter), member 37
chr8_+_41037541 0.36 ENSDART00000129344
glycerol-3-phosphate acyltransferase 2, mitochondrial
chr17_-_41798856 0.36 ENSDART00000156031
ENSDART00000192801
ENSDART00000180172
ENSDART00000084745
ENSDART00000175577
Ral GTPase activating protein, alpha subunit 2 (catalytic)
chr10_+_6884123 0.36 ENSDART00000149095
ENSDART00000148772
ENSDART00000149334
DEAD (Asp-Glu-Ala-Asp) box polypeptide 4
chr3_+_18807006 0.36 ENSDART00000180091
transportin 2 (importin 3, karyopherin beta 2b)
chr5_-_20491198 0.36 ENSDART00000183051
ENSDART00000144232
FIC domain containing
chr22_-_17652914 0.36 ENSDART00000138483
si:ch73-243b8.4
chr2_+_41926707 0.36 ENSDART00000023208
zgc:110183
chr20_-_38787341 0.35 ENSDART00000136771
DnaJ (Hsp40) homolog, subfamily C, member 5 gamma a
chr15_-_1038193 0.35 ENSDART00000159462
si:dkey-77f5.3
chr10_-_32494304 0.35 ENSDART00000028161
UV radiation resistance associated gene
chr1_+_24557414 0.35 ENSDART00000076519
dCTP pyrophosphatase 1
chr17_-_16422654 0.35 ENSDART00000150149
tyrosyl-DNA phosphodiesterase 1
chr15_+_34934568 0.35 ENSDART00000165210
zgc:66024
chr5_-_45958838 0.35 ENSDART00000135072
POC5 centriolar protein homolog (Chlamydomonas)
chr8_+_3431671 0.35 ENSDART00000017850
cytosolic thiouridylase subunit 1 homolog (S. pombe)
chr5_+_37903790 0.35 ENSDART00000162470
transmembrane protease, serine 4b
chr18_+_36786842 0.35 ENSDART00000123264
si:ch211-160d20.3
chr8_+_21254192 0.35 ENSDART00000167718
inositol 1,4,5-trisphosphate receptor, type 3
chr25_-_27621268 0.34 ENSDART00000146205
ENSDART00000073511
hyaluronoglucosaminidase 6
chr14_-_33945692 0.34 ENSDART00000168546
ENSDART00000189778
zinc finger, DHHC-type containing 24
chr22_-_14739491 0.34 ENSDART00000133385
low density lipoprotein receptor-related protein 1Ba
chr14_-_899170 0.34 ENSDART00000165211
ENSDART00000031992
regulator of G protein signaling 14a
chr22_+_39096911 0.34 ENSDART00000157127
ENSDART00000153841
LIM and cysteine-rich domains 1
chr17_+_26722904 0.34 ENSDART00000114927
NRDE-2, necessary for RNA interference, domain containing
chr17_-_1703259 0.34 ENSDART00000156489
x globin
chr1_+_18811679 0.33 ENSDART00000078610
solute carrier family 25, member 51a
chr15_-_44601331 0.33 ENSDART00000161514
zgc:165508
chr22_+_35275468 0.33 ENSDART00000189516
ENSDART00000181572
ENSDART00000165353
ENSDART00000185352
RUN domain and cysteine-rich domain containing, Beclin 1-interacting protein
chr10_-_8046764 0.33 ENSDART00000099031
zgc:136254
chr17_+_16046132 0.33 ENSDART00000155005
si:ch73-204p21.2
chr22_-_547748 0.33 ENSDART00000037455
ENSDART00000140101
cyclin D3
chr21_-_32060993 0.33 ENSDART00000131651
si:ch211-160j14.2
chr25_-_21031007 0.33 ENSDART00000138985
guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide a
chr19_-_30510259 0.33 ENSDART00000135128
ENSDART00000186169
ENSDART00000182974
ENSDART00000187797
BCL2 associated athanogene 6, like
chr5_+_35786141 0.33 ENSDART00000022043
ENSDART00000127383
StAR-related lipid transfer (START) domain containing 8
chr22_-_23267893 0.33 ENSDART00000105613
si:dkey-121a9.3
chr18_-_43884044 0.33 ENSDART00000087382
DEAD (Asp-Glu-Ala-Asp) box helicase 6
chr3_-_30488063 0.32 ENSDART00000055393
ENSDART00000151367
mediator complex subunit 25
chr3_+_28860283 0.32 ENSDART00000077235
ALG1, chitobiosyldiphosphodolichol beta-mannosyltransferase
chr23_+_2789422 0.32 ENSDART00000156954
phospholipase C, gamma 1
chr22_-_10440688 0.32 ENSDART00000111962
nucleolar protein 8
chr14_+_39258569 0.32 ENSDART00000103298
diaphanous-related formin 2
chr5_+_6672870 0.32 ENSDART00000126598
paxillin a
chr9_+_9927516 0.32 ENSDART00000161089
ENSDART00000168559
transcription termination factor, RNA polymerase II
chr24_-_5713799 0.32 ENSDART00000137293
deleted in autism 1b
chr16_+_17763848 0.32 ENSDART00000149408
ENSDART00000148878
thioesterase superfamily member 4
chr10_+_1849874 0.32 ENSDART00000158897
ENSDART00000149956
adenomatous polyposis coli
chr8_+_2656231 0.31 ENSDART00000160833
family with sequence similarity 102, member Aa
chr17_-_40956035 0.31 ENSDART00000124715
si:dkey-16j16.4
chr13_+_23095228 0.31 ENSDART00000189068
ENSDART00000188624
phosphoinositide-3-kinase adaptor protein 1
chr19_-_25081711 0.31 ENSDART00000058513
XK, Kell blood group complex subunit-related family, member 8, tandem duplicate 3
chr25_+_28158352 0.31 ENSDART00000151854
Ca++-dependent secretion activator 2
chr3_+_22035863 0.31 ENSDART00000177169
cell division cycle 27
chr13_-_32726178 0.31 ENSDART00000012232
prenyl (decaprenyl) diphosphate synthase, subunit 2
chr6_+_4387150 0.31 ENSDART00000181283
RNA binding motif protein 26
chr3_-_3366590 0.31 ENSDART00000109428
ENSDART00000175329
si:dkey-46g23.1
chr21_-_3672343 0.31 ENSDART00000086492
ATPase phospholipid transporting 8B1
chr2_+_41526904 0.31 ENSDART00000127520
activin A receptor, type 1 like
chr8_+_11325310 0.31 ENSDART00000142577
frataxin
chr8_+_49117518 0.31 ENSDART00000079631
RAD21 cohesin complex component like 1
chr17_+_18031304 0.31 ENSDART00000127259
SET domain containing 3
chr11_+_11303458 0.30 ENSDART00000162486
ENSDART00000160703
si:dkey-23f9.4
chr23_+_2704793 0.30 ENSDART00000147953
nuclear receptor coactivator 6
chr6_+_40922572 0.30 ENSDART00000133599
ENSDART00000002728
ENSDART00000145153
eukaryotic translation initiation factor 4E nuclear import factor 1
chr4_+_13586689 0.30 ENSDART00000067161
ENSDART00000138201
transportin 3
chr8_-_22274222 0.30 ENSDART00000131805
nephronophthisis 4
chr6_-_15065376 0.30 ENSDART00000087797
transforming growth factor, beta receptor associated protein 1
chr23_-_19686791 0.30 ENSDART00000161973
zgc:193598
chr3_+_17933132 0.30 ENSDART00000104299
ENSDART00000162144
ENSDART00000162242
ENSDART00000166289
ENSDART00000171101
ENSDART00000164853
2',3'-cyclic nucleotide 3' phosphodiesterase
chr17_-_2690083 0.30 ENSDART00000135374
protein tyrosine phosphatase, non-receptor type 21
chr21_-_2814709 0.30 ENSDART00000097664
semaphorin 4D
chr8_-_20230802 0.30 ENSDART00000063400
MLLT1, super elongation complex subunit a
chr14_+_51056605 0.29 ENSDART00000159639

chr21_+_13383413 0.29 ENSDART00000151345
zgc:113162

Network of associatons between targets according to the STRING database.

First level regulatory network of si:dkey-43p13.5+uncx

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 2.8 GO:0016338 calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules(GO:0016338)
0.2 1.6 GO:0043046 DNA methylation involved in gamete generation(GO:0043046)
0.2 0.9 GO:0060283 negative regulation of oocyte development(GO:0060283)
0.2 0.9 GO:0030718 germ-line stem cell population maintenance(GO:0030718)
0.2 0.7 GO:0072111 spinal cord anterior/posterior patterning(GO:0021512) cell proliferation involved in pronephros development(GO:0039015) cell proliferation involved in kidney development(GO:0072111)
0.2 0.6 GO:0090219 negative regulation of phosphatidylinositol 3-kinase activity(GO:0043553) negative regulation of lipid kinase activity(GO:0090219)
0.2 0.6 GO:0000212 meiotic spindle organization(GO:0000212)
0.2 0.5 GO:0097067 cellular response to thyroid hormone stimulus(GO:0097067)
0.2 0.5 GO:1900182 positive regulation of protein localization to nucleus(GO:1900182) regulation of protein localization to Cajal body(GO:1904869) positive regulation of protein localization to Cajal body(GO:1904871)
0.1 0.9 GO:0042795 snRNA transcription from RNA polymerase II promoter(GO:0042795)
0.1 0.7 GO:1900145 nodal signaling pathway involved in determination of left/right asymmetry(GO:0038107) regulation of nodal signaling pathway involved in determination of left/right asymmetry(GO:1900145)
0.1 2.1 GO:0051445 regulation of meiotic cell cycle(GO:0051445)
0.1 0.4 GO:0031441 negative regulation of mRNA 3'-end processing(GO:0031441) negative regulation of mRNA polyadenylation(GO:1900364)
0.1 0.4 GO:0009211 pyrimidine deoxyribonucleoside triphosphate metabolic process(GO:0009211)
0.1 0.3 GO:0035477 regulation of angioblast cell migration involved in selective angioblast sprouting(GO:0035477)
0.1 1.3 GO:0006607 NLS-bearing protein import into nucleus(GO:0006607)
0.1 1.7 GO:0035803 binding of sperm to zona pellucida(GO:0007339) egg coat formation(GO:0035803) regulation of acrosome reaction(GO:0060046) positive regulation of acrosome reaction(GO:2000344)
0.1 0.5 GO:0010482 epidermal cell division(GO:0010481) regulation of epidermal cell division(GO:0010482)
0.1 0.5 GO:0000012 single strand break repair(GO:0000012)
0.1 0.4 GO:0051660 establishment of centrosome localization(GO:0051660)
0.1 0.3 GO:0006089 lactate metabolic process(GO:0006089)
0.1 0.4 GO:0046166 methylglyoxal biosynthetic process(GO:0019242) glyceraldehyde-3-phosphate biosynthetic process(GO:0046166)
0.1 0.6 GO:1902292 cell cycle DNA replication initiation(GO:1902292) nuclear cell cycle DNA replication initiation(GO:1902315) mitotic DNA replication initiation(GO:1902975)
0.1 0.5 GO:0046485 ether lipid metabolic process(GO:0046485)
0.1 0.4 GO:1990511 piRNA biosynthetic process(GO:1990511)
0.1 0.4 GO:2000096 positive regulation of Wnt signaling pathway, planar cell polarity pathway(GO:2000096)
0.1 0.3 GO:0045002 double-strand break repair via single-strand annealing(GO:0045002)
0.1 0.4 GO:0019254 carnitine metabolic process, CoA-linked(GO:0019254)
0.1 0.3 GO:1905067 endodermal digestive tract morphogenesis(GO:0061031) Wnt signaling pathway involved in somitogenesis(GO:0090244) negative regulation of canonical Wnt signaling pathway involved in heart development(GO:1905067)
0.1 0.3 GO:0035124 embryonic caudal fin morphogenesis(GO:0035124)
0.1 0.4 GO:0016191 synaptic vesicle uncoating(GO:0016191)
0.1 0.6 GO:0034063 stress granule assembly(GO:0034063)
0.1 0.3 GO:0006297 nucleotide-excision repair, DNA gap filling(GO:0006297)
0.1 0.7 GO:0006622 protein targeting to lysosome(GO:0006622)
0.1 0.3 GO:0048210 Golgi vesicle fusion to target membrane(GO:0048210)
0.1 0.4 GO:0000455 enzyme-directed rRNA pseudouridine synthesis(GO:0000455)
0.1 0.3 GO:0032447 tRNA wobble position uridine thiolation(GO:0002143) protein urmylation(GO:0032447)
0.1 0.2 GO:0072592 oxygen metabolic process(GO:0072592) regulation of oxygen metabolic process(GO:2000374) positive regulation of oxygen metabolic process(GO:2000376)
0.1 0.6 GO:0046548 retinal rod cell development(GO:0046548)
0.1 0.2 GO:0070987 error-free translesion synthesis(GO:0070987)
0.1 0.4 GO:0032732 positive regulation of interleukin-1 production(GO:0032732)
0.1 0.2 GO:0002566 somatic diversification of immune receptors via somatic mutation(GO:0002566) pyrimidine dimer repair(GO:0006290) somatic hypermutation of immunoglobulin genes(GO:0016446)
0.1 0.2 GO:0048308 organelle inheritance(GO:0048308) Golgi inheritance(GO:0048313)
0.1 0.5 GO:0071816 tail-anchored membrane protein insertion into ER membrane(GO:0071816)
0.1 2.7 GO:1904029 regulation of cyclin-dependent protein serine/threonine kinase activity(GO:0000079) regulation of cyclin-dependent protein kinase activity(GO:1904029)
0.1 0.2 GO:0042308 regulation of protein import into nucleus(GO:0042306) negative regulation of protein import into nucleus(GO:0042308) negative regulation of nucleocytoplasmic transport(GO:0046823) regulation of protein localization to nucleus(GO:1900180) negative regulation of protein localization to nucleus(GO:1900181) regulation of protein import(GO:1904589) negative regulation of protein import(GO:1904590)
0.1 0.3 GO:0006978 DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator(GO:0006978) DNA damage response, signal transduction resulting in transcription(GO:0042772)
0.1 0.2 GO:2001244 positive regulation of intrinsic apoptotic signaling pathway(GO:2001244)
0.1 0.6 GO:0000002 mitochondrial genome maintenance(GO:0000002)
0.0 0.7 GO:0035493 SNARE complex assembly(GO:0035493)
0.0 0.3 GO:0031048 chromatin silencing by small RNA(GO:0031048)
0.0 0.4 GO:0044528 regulation of mitochondrial mRNA stability(GO:0044528)
0.0 0.2 GO:0043461 proton-transporting ATP synthase complex assembly(GO:0043461) proton-transporting ATP synthase complex biogenesis(GO:0070272)
0.0 0.5 GO:0006611 protein export from nucleus(GO:0006611)
0.0 0.3 GO:0048011 neurotrophin TRK receptor signaling pathway(GO:0048011)
0.0 0.2 GO:0060049 regulation of protein glycosylation(GO:0060049)
0.0 0.4 GO:0007143 female meiotic division(GO:0007143)
0.0 0.3 GO:0018026 peptidyl-lysine monomethylation(GO:0018026)
0.0 0.4 GO:0043928 exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay(GO:0043928)
0.0 0.3 GO:0060347 ventricular trabecula myocardium morphogenesis(GO:0003222) trabecula formation(GO:0060343) heart trabecula formation(GO:0060347) skin epidermis development(GO:0098773)
0.0 0.2 GO:0036344 platelet formation(GO:0030220) platelet morphogenesis(GO:0036344)
0.0 1.9 GO:0060968 regulation of gene silencing(GO:0060968)
0.0 0.3 GO:0034058 endosomal vesicle fusion(GO:0034058)
0.0 0.1 GO:0016045 detection of biotic stimulus(GO:0009595) detection of bacterium(GO:0016045) detection of other organism(GO:0098543) detection of external biotic stimulus(GO:0098581)
0.0 0.3 GO:0001672 regulation of chromatin assembly or disassembly(GO:0001672)
0.0 0.2 GO:0006370 7-methylguanosine mRNA capping(GO:0006370)
0.0 0.2 GO:0048478 replication fork protection(GO:0048478)
0.0 0.1 GO:0021611 facial nerve formation(GO:0021611)
0.0 0.3 GO:0060976 coronary vasculature development(GO:0060976)
0.0 0.1 GO:2001295 malonyl-CoA biosynthetic process(GO:2001295)
0.0 0.2 GO:0016572 histone phosphorylation(GO:0016572)
0.0 0.1 GO:0042373 vitamin K metabolic process(GO:0042373) cellular response to fluid shear stress(GO:0071498)
0.0 0.7 GO:1902285 semaphorin-plexin signaling pathway involved in neuron projection guidance(GO:1902285) semaphorin-plexin signaling pathway involved in axon guidance(GO:1902287)
0.0 0.3 GO:1990414 replication-born double-strand break repair via sister chromatid exchange(GO:1990414)
0.0 0.3 GO:0006390 transcription from mitochondrial promoter(GO:0006390)
0.0 0.1 GO:0010259 multicellular organism aging(GO:0010259)
0.0 0.3 GO:0032205 negative regulation of telomere maintenance(GO:0032205)
0.0 0.2 GO:0070285 pigment cell development(GO:0070285)
0.0 0.2 GO:0035871 protein K11-linked deubiquitination(GO:0035871)
0.0 0.6 GO:0006491 N-glycan processing(GO:0006491)
0.0 0.3 GO:0006465 signal peptide processing(GO:0006465)
0.0 0.3 GO:2000251 positive regulation of actin cytoskeleton reorganization(GO:2000251)
0.0 0.7 GO:1990126 retrograde transport, endosome to plasma membrane(GO:1990126)
0.0 0.3 GO:0070782 phosphatidylserine exposure on apoptotic cell surface(GO:0070782)
0.0 0.1 GO:0008635 activation of cysteine-type endopeptidase activity involved in apoptotic process by cytochrome c(GO:0008635)
0.0 0.5 GO:0006044 N-acetylglucosamine metabolic process(GO:0006044)
0.0 0.2 GO:0051315 attachment of mitotic spindle microtubules to kinetochore(GO:0051315)
0.0 0.1 GO:0032776 DNA methylation on cytosine(GO:0032776)
0.0 0.7 GO:0006515 misfolded or incompletely synthesized protein catabolic process(GO:0006515)
0.0 0.1 GO:0007217 tachykinin receptor signaling pathway(GO:0007217)
0.0 0.4 GO:0061055 myotome development(GO:0061055)
0.0 0.3 GO:0030214 hyaluronan catabolic process(GO:0030214)
0.0 0.1 GO:0035479 angioblast cell migration from lateral mesoderm to midline(GO:0035479)
0.0 0.1 GO:0060330 regulation of response to interferon-gamma(GO:0060330) regulation of interferon-gamma-mediated signaling pathway(GO:0060334)
0.0 0.9 GO:0018230 peptidyl-L-cysteine S-palmitoylation(GO:0018230) peptidyl-S-diacylglycerol-L-cysteine biosynthetic process from peptidyl-cysteine(GO:0018231)
0.0 0.2 GO:0003365 establishment of cell polarity involved in ameboidal cell migration(GO:0003365)
0.0 0.2 GO:0072395 signal transduction involved in cell cycle checkpoint(GO:0072395)
0.0 0.2 GO:0048280 vesicle fusion with Golgi apparatus(GO:0048280)
0.0 0.3 GO:1902101 positive regulation of mitotic metaphase/anaphase transition(GO:0045842) positive regulation of mitotic sister chromatid separation(GO:1901970) positive regulation of metaphase/anaphase transition of cell cycle(GO:1902101)
0.0 0.8 GO:0045332 phospholipid translocation(GO:0045332)
0.0 0.1 GO:1904356 regulation of telomere maintenance via telomere lengthening(GO:1904356)
0.0 0.3 GO:1990504 dense core granule exocytosis(GO:1990504)
0.0 0.3 GO:0006382 adenosine to inosine editing(GO:0006382)
0.0 0.7 GO:0070593 dendrite self-avoidance(GO:0070593)
0.0 0.2 GO:0044857 membrane raft assembly(GO:0001765) plasma membrane raft assembly(GO:0044854) plasma membrane raft organization(GO:0044857) caveola assembly(GO:0070836)
0.0 0.1 GO:0018214 peptidyl-glutamic acid carboxylation(GO:0017187) protein carboxylation(GO:0018214)
0.0 0.1 GO:0097101 blood vessel endothelial cell fate specification(GO:0097101)
0.0 0.4 GO:1901534 positive regulation of hematopoietic progenitor cell differentiation(GO:1901534)
0.0 1.5 GO:0034504 protein localization to nucleus(GO:0034504)
0.0 0.5 GO:2000401 regulation of lymphocyte migration(GO:2000401)
0.0 0.8 GO:0000266 mitochondrial fission(GO:0000266)
0.0 0.5 GO:0050796 regulation of insulin secretion(GO:0050796)
0.0 0.4 GO:0008354 germ cell migration(GO:0008354)
0.0 0.3 GO:0032511 late endosome to vacuole transport via multivesicular body sorting pathway(GO:0032511)
0.0 0.1 GO:0006772 thiamine metabolic process(GO:0006772) thiamine-containing compound metabolic process(GO:0042723)
0.0 0.3 GO:1900153 miRNA mediated inhibition of translation(GO:0035278) negative regulation of translation, ncRNA-mediated(GO:0040033) regulation of translation, ncRNA-mediated(GO:0045974) regulation of nuclear-transcribed mRNA poly(A) tail shortening(GO:0060211) positive regulation of nuclear-transcribed mRNA poly(A) tail shortening(GO:0060213) positive regulation of mRNA catabolic process(GO:0061014) regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay(GO:1900151) positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay(GO:1900153)
0.0 0.2 GO:0002753 cytoplasmic pattern recognition receptor signaling pathway(GO:0002753)
0.0 0.3 GO:0007076 mitotic chromosome condensation(GO:0007076)
0.0 0.2 GO:0071479 cellular response to ionizing radiation(GO:0071479)
0.0 0.1 GO:0043620 regulation of transcription from RNA polymerase II promoter in response to stress(GO:0043618) regulation of DNA-templated transcription in response to stress(GO:0043620)
0.0 0.5 GO:0043249 erythrocyte maturation(GO:0043249)
0.0 0.1 GO:0042138 meiotic DNA double-strand break formation(GO:0042138)
0.0 0.1 GO:0000393 spliceosomal conformational changes to generate catalytic conformation(GO:0000393)
0.0 0.2 GO:0016185 synaptic vesicle budding from presynaptic endocytic zone membrane(GO:0016185)
0.0 0.1 GO:0045721 negative regulation of gluconeogenesis(GO:0045721)
0.0 0.3 GO:0016926 protein desumoylation(GO:0016926)
0.0 0.2 GO:0038203 TORC2 signaling(GO:0038203)
0.0 0.2 GO:0043490 acidic amino acid transport(GO:0015800) aspartate transport(GO:0015810) L-glutamate transport(GO:0015813) malate-aspartate shuttle(GO:0043490)
0.0 0.2 GO:0070301 cellular response to hydrogen peroxide(GO:0070301)
0.0 0.2 GO:0050962 detection of light stimulus involved in visual perception(GO:0050908) detection of light stimulus involved in sensory perception(GO:0050962)
0.0 0.2 GO:0072584 caveolin-mediated endocytosis(GO:0072584) negative regulation of clathrin-mediated endocytosis(GO:1900186) regulation of caveolin-mediated endocytosis(GO:2001286) negative regulation of caveolin-mediated endocytosis(GO:2001287)
0.0 0.2 GO:0060754 mast cell chemotaxis(GO:0002551) regulation of mast cell chemotaxis(GO:0060753) positive regulation of mast cell chemotaxis(GO:0060754) mast cell migration(GO:0097531)
0.0 0.1 GO:0032289 central nervous system myelin formation(GO:0032289)
0.0 0.1 GO:0010755 regulation of plasminogen activation(GO:0010755)
0.0 0.1 GO:1903334 regulation of protein folding(GO:1903332) positive regulation of protein folding(GO:1903334) regulation of chaperone-mediated protein folding(GO:1903644) positive regulation of chaperone-mediated protein folding(GO:1903646)
0.0 0.1 GO:0043416 regulation of skeletal muscle tissue regeneration(GO:0043416)
0.0 0.1 GO:0009298 GDP-mannose biosynthetic process(GO:0009298)
0.0 0.1 GO:0071543 diphosphoinositol polyphosphate metabolic process(GO:0071543) diadenosine pentaphosphate metabolic process(GO:1901906) diadenosine pentaphosphate catabolic process(GO:1901907) diadenosine hexaphosphate metabolic process(GO:1901908) diadenosine hexaphosphate catabolic process(GO:1901909) adenosine 5'-(hexahydrogen pentaphosphate) metabolic process(GO:1901910) adenosine 5'-(hexahydrogen pentaphosphate) catabolic process(GO:1901911)
0.0 0.3 GO:0060088 auditory receptor cell stereocilium organization(GO:0060088)
0.0 0.2 GO:0060236 regulation of mitotic spindle organization(GO:0060236) regulation of spindle organization(GO:0090224)
0.0 0.2 GO:0043435 response to corticotropin-releasing hormone(GO:0043435) cellular response to corticotropin-releasing hormone stimulus(GO:0071376)
0.0 0.3 GO:0006744 ubiquinone metabolic process(GO:0006743) ubiquinone biosynthetic process(GO:0006744) quinone metabolic process(GO:1901661) quinone biosynthetic process(GO:1901663)
0.0 0.2 GO:0000727 double-strand break repair via break-induced replication(GO:0000727)
0.0 0.4 GO:0090557 establishment of endothelial intestinal barrier(GO:0090557)
0.0 0.5 GO:0031047 gene silencing by RNA(GO:0031047)
0.0 0.1 GO:0000395 mRNA 5'-splice site recognition(GO:0000395)
0.0 0.1 GO:0051013 microtubule severing(GO:0051013)
0.0 1.1 GO:0017148 negative regulation of translation(GO:0017148)
0.0 0.0 GO:0019563 glycerol catabolic process(GO:0019563)
0.0 0.1 GO:0006895 Golgi to endosome transport(GO:0006895)
0.0 0.1 GO:0052651 phosphatidylserine catabolic process(GO:0006660) monoacylglycerol metabolic process(GO:0046462) monoacylglycerol catabolic process(GO:0052651)
0.0 0.2 GO:0042771 intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator(GO:0042771)
0.0 0.1 GO:0009264 deoxyribonucleotide catabolic process(GO:0009264) deoxyribose phosphate catabolic process(GO:0046386)
0.0 0.2 GO:0006228 UTP biosynthetic process(GO:0006228) UTP metabolic process(GO:0046051)
0.0 0.4 GO:0006623 protein targeting to vacuole(GO:0006623)
0.0 0.4 GO:0007632 visual behavior(GO:0007632)
0.0 0.0 GO:0030219 megakaryocyte differentiation(GO:0030219)
0.0 0.2 GO:0033173 calcineurin-NFAT signaling cascade(GO:0033173)
0.0 0.2 GO:0035999 tetrahydrofolate interconversion(GO:0035999)
0.0 0.4 GO:0055064 chloride ion homeostasis(GO:0055064)
0.0 0.2 GO:0045670 regulation of osteoclast differentiation(GO:0045670)
0.0 0.2 GO:0006047 UDP-N-acetylglucosamine metabolic process(GO:0006047)
0.0 0.9 GO:0046854 phosphatidylinositol phosphorylation(GO:0046854)
0.0 0.1 GO:0006102 isocitrate metabolic process(GO:0006102)
0.0 0.2 GO:0035459 cargo loading into vesicle(GO:0035459)
0.0 0.3 GO:0061462 protein localization to lysosome(GO:0061462)
0.0 0.1 GO:0005513 detection of calcium ion(GO:0005513)
0.0 0.1 GO:0071156 regulation of cell cycle arrest(GO:0071156)
0.0 0.1 GO:0015743 thiosulfate transport(GO:0015709) oxaloacetate transport(GO:0015729) malate transport(GO:0015743) succinate transport(GO:0015744) succinate transmembrane transport(GO:0071422) malate transmembrane transport(GO:0071423)
0.0 0.1 GO:0010996 response to auditory stimulus(GO:0010996)
0.0 0.3 GO:0006879 cellular iron ion homeostasis(GO:0006879)
0.0 0.3 GO:0051014 actin filament severing(GO:0051014)
0.0 0.1 GO:0019883 antigen processing and presentation of endogenous peptide antigen(GO:0002483) antigen processing and presentation of endogenous antigen(GO:0019883) antigen processing and presentation of endogenous peptide antigen via MHC class I(GO:0019885)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.8 2.4 GO:0097124 cyclin A2-CDK2 complex(GO:0097124)
0.2 0.7 GO:0031310 integral component of vacuolar membrane(GO:0031166) intrinsic component of vacuolar membrane(GO:0031310)
0.2 0.7 GO:0097189 apoptotic body(GO:0097189)
0.2 1.6 GO:0071546 pi-body(GO:0071546)
0.2 0.5 GO:0019185 snRNA-activating protein complex(GO:0019185)
0.1 2.3 GO:0043186 P granule(GO:0043186)
0.1 0.2 GO:0031466 Cul5-RING ubiquitin ligase complex(GO:0031466)
0.1 0.5 GO:0071818 BAT3 complex(GO:0071818)
0.1 0.3 GO:0071458 integral component of cytoplasmic side of endoplasmic reticulum membrane(GO:0071458) integral component of lumenal side of endoplasmic reticulum membrane(GO:0071556) lumenal side of endoplasmic reticulum membrane(GO:0098553)
0.1 0.6 GO:0045171 intercellular bridge(GO:0045171)
0.1 0.3 GO:0070724 BMP receptor complex(GO:0070724)
0.1 0.3 GO:0043625 delta DNA polymerase complex(GO:0043625)
0.1 0.2 GO:0032301 MutSalpha complex(GO:0032301)
0.1 0.2 GO:0035301 Hedgehog signaling complex(GO:0035301)
0.0 0.2 GO:0033186 CAF-1 complex(GO:0033186)
0.0 0.1 GO:0010369 chromocenter(GO:0010369)
0.0 0.3 GO:0034991 nuclear cohesin complex(GO:0000798) mitotic cohesin complex(GO:0030892) nuclear mitotic cohesin complex(GO:0034990) nuclear meiotic cohesin complex(GO:0034991)
0.0 0.2 GO:0070390 transcription export complex 2(GO:0070390)
0.0 0.3 GO:0030877 beta-catenin destruction complex(GO:0030877)
0.0 1.5 GO:0010494 cytoplasmic stress granule(GO:0010494)
0.0 0.2 GO:0034098 VCP-NPL4-UFD1 AAA ATPase complex(GO:0034098)
0.0 0.8 GO:0042555 MCM complex(GO:0042555)
0.0 0.2 GO:0005880 nuclear microtubule(GO:0005880)
0.0 0.6 GO:0032391 photoreceptor connecting cilium(GO:0032391)
0.0 0.2 GO:0000811 GINS complex(GO:0000811)
0.0 0.7 GO:0002116 semaphorin receptor complex(GO:0002116)
0.0 0.7 GO:0030667 secretory granule membrane(GO:0030667)
0.0 0.4 GO:0030015 CCR4-NOT core complex(GO:0030015)
0.0 3.6 GO:0005923 bicellular tight junction(GO:0005923) occluding junction(GO:0070160)
0.0 0.1 GO:0000938 GARP complex(GO:0000938)
0.0 0.3 GO:0030140 trans-Golgi network transport vesicle(GO:0030140)
0.0 0.8 GO:0000421 autophagosome membrane(GO:0000421)
0.0 0.1 GO:0042824 MHC class I peptide loading complex(GO:0042824)
0.0 0.4 GO:0005682 U5 snRNP(GO:0005682)
0.0 0.4 GO:0097546 ciliary base(GO:0097546)
0.0 0.1 GO:0072669 tRNA-splicing ligase complex(GO:0072669)
0.0 0.5 GO:0045180 basal cortex(GO:0045180)
0.0 0.4 GO:0043296 apical junction complex(GO:0043296)
0.0 0.3 GO:0000815 ESCRT III complex(GO:0000815)
0.0 0.1 GO:0030121 AP-1 adaptor complex(GO:0030121)
0.0 0.2 GO:0098888 presynaptic endocytic zone(GO:0098833) presynaptic endocytic zone membrane(GO:0098835) extrinsic component of presynaptic membrane(GO:0098888) extrinsic component of presynaptic endocytic zone(GO:0098894)
0.0 0.3 GO:0005868 cytoplasmic dynein complex(GO:0005868)
0.0 0.1 GO:0070209 ASTRA complex(GO:0070209)
0.0 0.1 GO:0032838 cell projection cytoplasm(GO:0032838)
0.0 0.9 GO:0005657 replication fork(GO:0005657)
0.0 0.2 GO:0032420 stereocilium(GO:0032420)
0.0 0.2 GO:0009295 nucleoid(GO:0009295) mitochondrial nucleoid(GO:0042645)
0.0 0.1 GO:0035101 FACT complex(GO:0035101)
0.0 0.1 GO:0072379 ER membrane insertion complex(GO:0072379)
0.0 0.3 GO:1990124 messenger ribonucleoprotein complex(GO:1990124)
0.0 0.2 GO:0031080 nuclear pore outer ring(GO:0031080)
0.0 0.1 GO:0042622 photoreceptor outer segment membrane(GO:0042622)
0.0 0.8 GO:0005905 clathrin-coated pit(GO:0005905)
0.0 0.1 GO:0000506 glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex(GO:0000506)
0.0 0.2 GO:0005964 phosphorylase kinase complex(GO:0005964)
0.0 0.4 GO:0005921 gap junction(GO:0005921)
0.0 0.6 GO:0005876 spindle microtubule(GO:0005876)
0.0 0.1 GO:0035145 exon-exon junction complex(GO:0035145)
0.0 0.8 GO:0016592 mediator complex(GO:0016592)
0.0 0.1 GO:0000974 Prp19 complex(GO:0000974)
0.0 0.7 GO:0005643 nuclear pore(GO:0005643)
0.0 0.1 GO:0005943 phosphatidylinositol 3-kinase complex, class IA(GO:0005943)
0.0 0.1 GO:0005790 smooth endoplasmic reticulum(GO:0005790)
0.0 0.1 GO:0055087 Ski complex(GO:0055087)
0.0 0.1 GO:0000439 core TFIIH complex(GO:0000439)
0.0 0.2 GO:0005669 transcription factor TFIID complex(GO:0005669)
0.0 0.4 GO:0032154 cleavage furrow(GO:0032154) cell surface furrow(GO:0097610)
0.0 0.4 GO:0055038 recycling endosome membrane(GO:0055038)
0.0 0.2 GO:1990589 ATF4-CREB1 transcription factor complex(GO:1990589)
0.0 0.2 GO:0031462 Cul2-RING ubiquitin ligase complex(GO:0031462)
0.0 0.1 GO:0032797 SMN complex(GO:0032797)
0.0 1.2 GO:0005802 trans-Golgi network(GO:0005802)
0.0 0.1 GO:0034272 phosphatidylinositol 3-kinase complex, class III, type I(GO:0034271) phosphatidylinositol 3-kinase complex, class III, type II(GO:0034272)
0.0 0.1 GO:0035517 PR-DUB complex(GO:0035517)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 2.0 GO:0009374 biotin binding(GO:0009374)
0.1 1.2 GO:0034584 piRNA binding(GO:0034584)
0.1 0.9 GO:0070698 type I activin receptor binding(GO:0070698)
0.1 0.4 GO:0004466 long-chain-acyl-CoA dehydrogenase activity(GO:0004466)
0.1 0.6 GO:0043139 5'-3' DNA helicase activity(GO:0043139)
0.1 0.3 GO:0070259 tyrosyl-DNA phosphodiesterase activity(GO:0070259)
0.1 0.3 GO:0033961 cis-stilbene-oxide hydrolase activity(GO:0033961)
0.1 0.5 GO:0042809 vitamin D receptor binding(GO:0042809)
0.1 1.7 GO:0032190 acrosin binding(GO:0032190)
0.1 0.3 GO:0004113 2',3'-cyclic-nucleotide 3'-phosphodiesterase activity(GO:0004113)
0.1 1.6 GO:0061608 nuclear import signal receptor activity(GO:0061608)
0.1 0.4 GO:0004807 triose-phosphate isomerase activity(GO:0004807) methylglyoxal synthase activity(GO:0008929)
0.1 0.4 GO:0030228 lipoprotein particle receptor activity(GO:0030228)
0.1 0.3 GO:0070336 flap-structured DNA binding(GO:0070336)
0.1 0.3 GO:0001605 adrenomedullin receptor activity(GO:0001605) calcitonin gene-related peptide receptor activity(GO:0001635)
0.1 1.2 GO:0008266 poly(U) RNA binding(GO:0008266)
0.1 0.5 GO:0070016 armadillo repeat domain binding(GO:0070016)
0.1 0.2 GO:0016509 long-chain-3-hydroxyacyl-CoA dehydrogenase activity(GO:0016509)
0.1 0.3 GO:0070182 DNA polymerase binding(GO:0070182)
0.1 0.5 GO:0004430 1-phosphatidylinositol 4-kinase activity(GO:0004430)
0.1 0.6 GO:0004571 mannosyl-oligosaccharide 1,2-alpha-mannosidase activity(GO:0004571) mannosyl-oligosaccharide mannosidase activity(GO:0015924)
0.1 0.4 GO:0047429 nucleoside-triphosphate diphosphatase activity(GO:0047429)
0.1 0.2 GO:0004377 GDP-Man:Man3GlcNAc2-PP-Dol alpha-1,2-mannosyltransferase activity(GO:0004377)
0.1 0.2 GO:0016308 1-phosphatidylinositol-4-phosphate 5-kinase activity(GO:0016308)
0.1 0.2 GO:0033819 lipoyl(octanoyl) transferase activity(GO:0033819)
0.1 0.2 GO:0032357 guanine/thymine mispair binding(GO:0032137) single base insertion or deletion binding(GO:0032138) single thymine insertion binding(GO:0032143) oxidized DNA binding(GO:0032356) oxidized purine DNA binding(GO:0032357) mismatch repair complex binding(GO:0032404) MutLalpha complex binding(GO:0032405)
0.0 0.4 GO:0008143 poly(A) binding(GO:0008143)
0.0 0.3 GO:0098809 nitrite reductase activity(GO:0098809)
0.0 0.3 GO:0034450 ubiquitin-ubiquitin ligase activity(GO:0034450)
0.0 0.2 GO:0051377 mannose-ethanolamine phosphotransferase activity(GO:0051377)
0.0 0.1 GO:0031835 neurokinin receptor binding(GO:0031834) substance P receptor binding(GO:0031835)
0.0 0.6 GO:0043028 cysteine-type endopeptidase inhibitor activity involved in apoptotic process(GO:0043027) cysteine-type endopeptidase regulator activity involved in apoptotic process(GO:0043028)
0.0 2.7 GO:0016538 cyclin-dependent protein serine/threonine kinase regulator activity(GO:0016538)
0.0 0.4 GO:0005381 iron ion transmembrane transporter activity(GO:0005381)
0.0 0.2 GO:0010521 telomerase inhibitor activity(GO:0010521)
0.0 0.2 GO:0004689 phosphorylase kinase activity(GO:0004689)
0.0 0.3 GO:0016530 metallochaperone activity(GO:0016530)
0.0 0.5 GO:0051864 histone demethylase activity (H3-K36 specific)(GO:0051864)
0.0 0.1 GO:0046978 TAP1 binding(GO:0046978)
0.0 0.2 GO:0004679 AMP-activated protein kinase activity(GO:0004679)
0.0 0.1 GO:0016019 peptidoglycan receptor activity(GO:0016019)
0.0 0.3 GO:0003835 beta-galactoside alpha-2,6-sialyltransferase activity(GO:0003835)
0.0 0.5 GO:0036312 phosphatidylinositol 3-kinase regulatory subunit binding(GO:0036312)
0.0 0.2 GO:0004185 serine-type carboxypeptidase activity(GO:0004185)
0.0 0.3 GO:0016714 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced pteridine as one donor, and incorporation of one atom of oxygen(GO:0016714)
0.0 0.2 GO:0000995 transcription factor activity, core RNA polymerase III binding(GO:0000995)
0.0 0.2 GO:0017150 tRNA dihydrouridine synthase activity(GO:0017150)
0.0 0.2 GO:0008139 nuclear localization sequence binding(GO:0008139)
0.0 0.1 GO:0003989 acetyl-CoA carboxylase activity(GO:0003989)
0.0 0.3 GO:0042500 aspartic endopeptidase activity, intramembrane cleaving(GO:0042500)
0.0 0.1 GO:0050333 thiamin-triphosphatase activity(GO:0050333)
0.0 0.1 GO:0008179 adenylate cyclase binding(GO:0008179)
0.0 0.4 GO:0035250 UDP-galactosyltransferase activity(GO:0035250)
0.0 0.1 GO:0008761 UDP-N-acetylglucosamine 2-epimerase activity(GO:0008761) N-acylmannosamine kinase activity(GO:0009384)
0.0 0.4 GO:0031726 CCR1 chemokine receptor binding(GO:0031726) CCR4 chemokine receptor binding(GO:0031729)
0.0 0.2 GO:0031419 cobalamin binding(GO:0031419)
0.0 2.4 GO:0003724 RNA helicase activity(GO:0003724)
0.0 0.3 GO:0005220 inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity(GO:0005220)
0.0 0.2 GO:0004329 formate-tetrahydrofolate ligase activity(GO:0004329)
0.0 0.7 GO:0004659 prenyltransferase activity(GO:0004659)
0.0 0.4 GO:0031267 small GTPase binding(GO:0031267)
0.0 0.3 GO:0004415 hyalurononglucosaminidase activity(GO:0004415)
0.0 0.2 GO:0032052 bile acid binding(GO:0032052)
0.0 0.8 GO:0032266 phosphatidylinositol-3-phosphate binding(GO:0032266)
0.0 0.3 GO:0002161 aminoacyl-tRNA editing activity(GO:0002161)
0.0 0.3 GO:0001965 G-protein alpha-subunit binding(GO:0001965)
0.0 0.3 GO:0008296 3'-5'-exodeoxyribonuclease activity(GO:0008296)
0.0 0.6 GO:0003688 DNA replication origin binding(GO:0003688)
0.0 0.1 GO:0004064 arylesterase activity(GO:0004064)
0.0 0.3 GO:0005025 transforming growth factor beta receptor activity, type I(GO:0005025)
0.0 0.4 GO:0004535 poly(A)-specific ribonuclease activity(GO:0004535)
0.0 0.3 GO:0031821 G-protein coupled serotonin receptor binding(GO:0031821)
0.0 0.1 GO:0003977 UDP-N-acetylglucosamine diphosphorylase activity(GO:0003977)
0.0 0.2 GO:0008118 N-acetyllactosaminide alpha-2,3-sialyltransferase activity(GO:0008118)
0.0 0.5 GO:0031492 nucleosomal DNA binding(GO:0031492)
0.0 0.3 GO:0003726 double-stranded RNA adenosine deaminase activity(GO:0003726)
0.0 0.4 GO:0005247 voltage-gated chloride channel activity(GO:0005247)
0.0 0.3 GO:0070628 proteasome binding(GO:0070628)
0.0 0.1 GO:0008488 gamma-glutamyl carboxylase activity(GO:0008488)
0.0 0.3 GO:0004711 ribosomal protein S6 kinase activity(GO:0004711)
0.0 0.4 GO:0009982 pseudouridine synthase activity(GO:0009982)
0.0 0.2 GO:0004176 ATP-dependent peptidase activity(GO:0004176)
0.0 0.2 GO:0042936 dipeptide transporter activity(GO:0042936) dipeptide transmembrane transporter activity(GO:0071916)
0.0 0.3 GO:0046975 histone methyltransferase activity (H3-K36 specific)(GO:0046975)
0.0 0.1 GO:0004605 phosphatidate cytidylyltransferase activity(GO:0004605)
0.0 0.7 GO:0098632 protein binding involved in cell-cell adhesion(GO:0098632)
0.0 0.9 GO:0003727 single-stranded RNA binding(GO:0003727)
0.0 0.2 GO:0052629 phosphatidylinositol-3,5-bisphosphate 3-phosphatase activity(GO:0052629)
0.0 0.4 GO:0070566 adenylyltransferase activity(GO:0070566)
0.0 0.9 GO:0019707 protein-cysteine S-palmitoyltransferase activity(GO:0019706) protein-cysteine S-acyltransferase activity(GO:0019707)
0.0 0.1 GO:0004449 isocitrate dehydrogenase (NAD+) activity(GO:0004449)
0.0 0.5 GO:0008171 O-methyltransferase activity(GO:0008171)
0.0 0.3 GO:0003756 protein disulfide isomerase activity(GO:0003756) intramolecular oxidoreductase activity, transposing S-S bonds(GO:0016864)
0.0 4.5 GO:0042802 identical protein binding(GO:0042802)
0.0 0.1 GO:0051185 coenzyme transporter activity(GO:0051185)
0.0 0.2 GO:0045503 dynein light chain binding(GO:0045503)
0.0 0.1 GO:0005219 ryanodine-sensitive calcium-release channel activity(GO:0005219) calcium-induced calcium release activity(GO:0048763)
0.0 0.1 GO:0008486 endopolyphosphatase activity(GO:0000298) diphosphoinositol-polyphosphate diphosphatase activity(GO:0008486) bis(5'-adenosyl)-hexaphosphatase activity(GO:0034431) bis(5'-adenosyl)-pentaphosphatase activity(GO:0034432)
0.0 0.3 GO:0016929 SUMO-specific protease activity(GO:0016929)
0.0 0.2 GO:0005522 profilin binding(GO:0005522)
0.0 0.2 GO:0005172 vascular endothelial growth factor receptor binding(GO:0005172)
0.0 0.2 GO:0005545 1-phosphatidylinositol binding(GO:0005545)
0.0 0.9 GO:0061631 ubiquitin conjugating enzyme activity(GO:0061631)
0.0 0.4 GO:0022829 wide pore channel activity(GO:0022829)
0.0 0.1 GO:0017176 phosphatidylinositol N-acetylglucosaminyltransferase activity(GO:0017176)
0.0 0.2 GO:0015183 L-aspartate transmembrane transporter activity(GO:0015183)
0.0 1.0 GO:0004527 exonuclease activity(GO:0004527)
0.0 0.2 GO:0051879 Hsp90 protein binding(GO:0051879)
0.0 0.4 GO:0042043 neurexin family protein binding(GO:0042043)
0.0 0.1 GO:0004826 phenylalanine-tRNA ligase activity(GO:0004826)
0.0 0.1 GO:0042975 peroxisome proliferator activated receptor binding(GO:0042975)
0.0 0.3 GO:0002039 p53 binding(GO:0002039)
0.0 0.2 GO:0035259 glucocorticoid receptor binding(GO:0035259)
0.0 0.1 GO:0034597 phosphatidylinositol-4,5-bisphosphate 4-phosphatase activity(GO:0034597)
0.0 0.5 GO:0051959 dynein light intermediate chain binding(GO:0051959)
0.0 0.1 GO:0043515 kinetochore binding(GO:0043515)
0.0 0.1 GO:0004359 glutaminase activity(GO:0004359)
0.0 0.2 GO:0016018 cyclosporin A binding(GO:0016018)
0.0 0.4 GO:0030165 PDZ domain binding(GO:0030165)
0.0 0.1 GO:0050699 WW domain binding(GO:0050699)
0.0 0.2 GO:0016409 palmitoyltransferase activity(GO:0016409)
0.0 0.3 GO:0000030 mannosyltransferase activity(GO:0000030)
0.0 0.1 GO:0072320 volume-sensitive chloride channel activity(GO:0072320)
0.0 1.0 GO:1901981 phosphatidylinositol phosphate binding(GO:1901981)
0.0 0.3 GO:0050321 tau-protein kinase activity(GO:0050321)
0.0 0.4 GO:0051018 protein kinase A binding(GO:0051018)
0.0 0.1 GO:0036042 long-chain fatty acyl-CoA binding(GO:0036042)
0.0 0.0 GO:0043621 protein self-association(GO:0043621)
0.0 0.1 GO:0035612 AP-2 adaptor complex binding(GO:0035612)
0.0 0.2 GO:0061665 SUMO ligase activity(GO:0061665)
0.0 0.2 GO:0017056 structural constituent of nuclear pore(GO:0017056)
0.0 1.2 GO:0035091 phosphatidylinositol binding(GO:0035091)
0.0 0.1 GO:0015140 thiosulfate transmembrane transporter activity(GO:0015117) oxaloacetate transmembrane transporter activity(GO:0015131) malate transmembrane transporter activity(GO:0015140)
0.0 0.8 GO:0003730 mRNA 3'-UTR binding(GO:0003730)
0.0 0.3 GO:0003899 DNA-directed RNA polymerase activity(GO:0003899) RNA polymerase activity(GO:0034062)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 2.4 SA REG CASCADE OF CYCLIN EXPR Expression of cyclins regulates progression through the cell cycle by activating cyclin-dependent kinases.
0.0 0.4 SA MMP CYTOKINE CONNECTION Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix.
0.0 0.5 PID SMAD2 3PATHWAY Regulation of cytoplasmic and nuclear SMAD2/3 signaling
0.0 0.4 PID S1P S1P4 PATHWAY S1P4 pathway
0.0 0.6 ST MYOCYTE AD PATHWAY Myocyte Adrenergic Pathway is a specific case of the generalized Adrenergic Pathway.
0.0 0.6 PID LIS1 PATHWAY Lissencephaly gene (LIS1) in neuronal migration and development
0.0 0.6 PID P38 MKK3 6PATHWAY p38 MAPK signaling pathway
0.0 0.3 PID TCR CALCIUM PATHWAY Calcium signaling in the CD4+ TCR pathway
0.0 0.2 PID RANBP2 PATHWAY Sumoylation by RanBP2 regulates transcriptional repression
0.0 0.7 PID AURORA B PATHWAY Aurora B signaling
0.0 0.5 PID ER NONGENOMIC PATHWAY Plasma membrane estrogen receptor signaling
0.0 0.4 PID HIF2PATHWAY HIF-2-alpha transcription factor network
0.0 0.7 PID FOXM1 PATHWAY FOXM1 transcription factor network
0.0 0.4 PID ECADHERIN KERATINOCYTE PATHWAY E-cadherin signaling in keratinocytes
0.0 1.2 PID AR PATHWAY Coregulation of Androgen receptor activity
0.0 0.9 PID TELOMERASE PATHWAY Regulation of Telomerase
0.0 0.2 ST WNT CA2 CYCLIC GMP PATHWAY Wnt/Ca2+/cyclic GMP signaling.
0.0 0.3 PID FAK PATHWAY Signaling events mediated by focal adhesion kinase
0.0 0.1 PID EPHB FWD PATHWAY EPHB forward signaling
0.0 0.3 PID PRL SIGNALING EVENTS PATHWAY Signaling events mediated by PRL
0.0 0.4 NABA PROTEOGLYCANS Genes encoding proteoglycans
0.0 0.3 PID AURORA A PATHWAY Aurora A signaling
0.0 0.2 ST P38 MAPK PATHWAY p38 MAPK Pathway
0.0 0.3 PID BARD1 PATHWAY BARD1 signaling events
0.0 0.5 PID MYC REPRESS PATHWAY Validated targets of C-MYC transcriptional repression
0.0 0.1 ST B CELL ANTIGEN RECEPTOR B Cell Antigen Receptor
0.0 1.8 NABA SECRETED FACTORS Genes encoding secreted soluble factors
0.0 0.2 PID VEGFR1 2 PATHWAY Signaling events mediated by VEGFR1 and VEGFR2
0.0 0.2 PID ARF 3PATHWAY Arf1 pathway

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 2.4 REACTOME CYCLIN A B1 ASSOCIATED EVENTS DURING G2 M TRANSITION Genes involved in Cyclin A/B1 associated events during G2/M transition
0.1 0.1 REACTOME INFLUENZA VIRAL RNA TRANSCRIPTION AND REPLICATION Genes involved in Influenza Viral RNA Transcription and Replication
0.1 0.3 REACTOME ROLE OF SECOND MESSENGERS IN NETRIN1 SIGNALING Genes involved in Role of second messengers in netrin-1 signaling
0.1 0.3 REACTOME ELEVATION OF CYTOSOLIC CA2 LEVELS Genes involved in Elevation of cytosolic Ca2+ levels
0.1 0.3 REACTOME NEGATIVE REGULATION OF THE PI3K AKT NETWORK Genes involved in Negative regulation of the PI3K/AKT network
0.0 0.9 REACTOME SIGNALING BY HIPPO Genes involved in Signaling by Hippo
0.0 0.4 REACTOME A TETRASACCHARIDE LINKER SEQUENCE IS REQUIRED FOR GAG SYNTHESIS Genes involved in A tetrasaccharide linker sequence is required for GAG synthesis
0.0 0.7 REACTOME HS GAG DEGRADATION Genes involved in HS-GAG degradation
0.0 0.2 REACTOME G2 M DNA DAMAGE CHECKPOINT Genes involved in G2/M DNA damage checkpoint
0.0 0.2 REACTOME REGULATION OF RHEB GTPASE ACTIVITY BY AMPK Genes involved in Regulation of Rheb GTPase activity by AMPK
0.0 0.6 REACTOME KINESINS Genes involved in Kinesins
0.0 0.4 REACTOME MITOCHONDRIAL FATTY ACID BETA OXIDATION Genes involved in Mitochondrial Fatty Acid Beta-Oxidation
0.0 0.7 REACTOME APC CDC20 MEDIATED DEGRADATION OF NEK2A Genes involved in APC-Cdc20 mediated degradation of Nek2A
0.0 0.4 REACTOME CTNNB1 PHOSPHORYLATION CASCADE Genes involved in Beta-catenin phosphorylation cascade
0.0 0.3 REACTOME REMOVAL OF THE FLAP INTERMEDIATE FROM THE C STRAND Genes involved in Removal of the Flap Intermediate from the C-strand
0.0 0.4 REACTOME DEADENYLATION OF MRNA Genes involved in Deadenylation of mRNA
0.0 1.2 REACTOME ION TRANSPORT BY P TYPE ATPASES Genes involved in Ion transport by P-type ATPases
0.0 0.2 REACTOME CHONDROITIN SULFATE BIOSYNTHESIS Genes involved in Chondroitin sulfate biosynthesis
0.0 0.2 REACTOME IRAK2 MEDIATED ACTIVATION OF TAK1 COMPLEX UPON TLR7 8 OR 9 STIMULATION Genes involved in IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation
0.0 0.3 REACTOME MRNA DECAY BY 5 TO 3 EXORIBONUCLEASE Genes involved in mRNA Decay by 5' to 3' Exoribonuclease
0.0 0.3 REACTOME YAP1 AND WWTR1 TAZ STIMULATED GENE EXPRESSION Genes involved in YAP1- and WWTR1 (TAZ)-stimulated gene expression
0.0 1.0 REACTOME MITOTIC PROMETAPHASE Genes involved in Mitotic Prometaphase
0.0 0.3 REACTOME DOUBLE STRAND BREAK REPAIR Genes involved in Double-Strand Break Repair
0.0 0.4 REACTOME CHOLESTEROL BIOSYNTHESIS Genes involved in Cholesterol biosynthesis
0.0 0.3 REACTOME SYNTHESIS OF PA Genes involved in Synthesis of PA
0.0 0.2 REACTOME UNWINDING OF DNA Genes involved in Unwinding of DNA
0.0 0.3 REACTOME OTHER SEMAPHORIN INTERACTIONS Genes involved in Other semaphorin interactions
0.0 0.4 REACTOME MEIOTIC SYNAPSIS Genes involved in Meiotic Synapsis
0.0 0.4 REACTOME INTERFERON GAMMA SIGNALING Genes involved in Interferon gamma signaling
0.0 0.4 REACTOME ANTIGEN ACTIVATES B CELL RECEPTOR LEADING TO GENERATION OF SECOND MESSENGERS Genes involved in Antigen Activates B Cell Receptor Leading to Generation of Second Messengers
0.0 0.4 REACTOME LYSOSOME VESICLE BIOGENESIS Genes involved in Lysosome Vesicle Biogenesis
0.0 0.2 REACTOME RNA POL III TRANSCRIPTION INITIATION FROM TYPE 2 PROMOTER Genes involved in RNA Polymerase III Transcription Initiation From Type 2 Promoter
0.0 0.4 REACTOME BIOSYNTHESIS OF THE N GLYCAN PRECURSOR DOLICHOL LIPID LINKED OLIGOSACCHARIDE LLO AND TRANSFER TO A NASCENT PROTEIN Genes involved in Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein
0.0 0.6 REACTOME MITOCHONDRIAL PROTEIN IMPORT Genes involved in Mitochondrial Protein Import
0.0 0.3 REACTOME ELONGATION ARREST AND RECOVERY Genes involved in Elongation arrest and recovery
0.0 0.1 REACTOME ACTIVATION OF CHAPERONES BY ATF6 ALPHA Genes involved in Activation of Chaperones by ATF6-alpha
0.0 0.1 REACTOME RETROGRADE NEUROTROPHIN SIGNALLING Genes involved in Retrograde neurotrophin signalling
0.0 0.5 REACTOME TRANSPORT TO THE GOLGI AND SUBSEQUENT MODIFICATION Genes involved in Transport to the Golgi and subsequent modification
0.0 0.1 REACTOME GLYCOGEN BREAKDOWN GLYCOGENOLYSIS Genes involved in Glycogen breakdown (glycogenolysis)
0.0 0.2 REACTOME SYNTHESIS AND INTERCONVERSION OF NUCLEOTIDE DI AND TRIPHOSPHATES Genes involved in Synthesis and interconversion of nucleotide di- and triphosphates
0.0 0.3 REACTOME MEIOTIC RECOMBINATION Genes involved in Meiotic Recombination
0.0 0.1 REACTOME TRANSCRIPTION COUPLED NER TC NER Genes involved in Transcription-coupled NER (TC-NER)