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PRJNA195909:zebrafish embryo and larva development

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Results for si:dkey-149i17.7_zic1

Z-value: 1.25

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Transcription factors associated with si:dkey-149i17.7_zic1

Gene Symbol Gene ID Gene Info
ENSDARG00000094684 si_dkey-149i17.7
ENSDARG00000015567 zic family member 1 (odd-paired homolog, Drosophila)

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
si:dkey-149i17.7dr11_v1_chr2_+_24885987_248859870.636.7e-02Click!
zic1dr11_v1_chr24_-_4973765_4973765-0.108.0e-01Click!

Activity profile of si:dkey-149i17.7_zic1 motif

Sorted Z-values of si:dkey-149i17.7_zic1 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr9_-_22158784 1.34 ENSDART00000167850
crystallin, gamma M2d14
chr7_-_24699985 1.32 ENSDART00000052802
calbindin 2b
chr15_+_9072821 1.24 ENSDART00000154463
si:dkey-202g17.3
chr20_-_43775495 0.96 ENSDART00000100610
ENSDART00000149001
ENSDART00000148809
ENSDART00000100608
matrilin 3a
chr18_+_907266 0.95 ENSDART00000171729
pyruvate kinase M1/2a
chr18_+_49411417 0.92 ENSDART00000028944
zmp:0000001073
chr24_-_3419998 0.82 ENSDART00000066839
solute carrier family 35, member G2b
chr17_-_6382392 0.82 ENSDART00000188051
ENSDART00000192560
ENSDART00000137389
ENSDART00000115389
taxilin beta b
chr19_+_43297546 0.81 ENSDART00000168002
lysosomal protein transmembrane 5
chr22_+_18886209 0.80 ENSDART00000144402
follistatin-like 3 (secreted glycoprotein)
chr14_-_51855047 0.78 ENSDART00000088912
complexin 1
chr19_-_32641725 0.74 ENSDART00000165006
ENSDART00000188185
hippocalcin
chr17_+_13664442 0.70 ENSDART00000171689
leucine rich repeat and fibronectin type III domain containing 5a
chr21_+_19445942 0.66 ENSDART00000030887
solute carrier family 45, member 2
chr18_+_39487486 0.63 ENSDART00000126978
acyl-CoA dehydrogenase long chain
chr16_-_55028740 0.62 ENSDART00000156368
ENSDART00000161704
zgc:114181
chr1_+_51496862 0.61 ENSDART00000150433
Meis homeobox 1 a
chr4_-_1324141 0.61 ENSDART00000180720
pleiotrophin
chr23_+_1349277 0.61 ENSDART00000173133
ENSDART00000179877
utrophin
chr19_+_42983613 0.61 ENSDART00000033724
fatty acid binding protein 3, muscle and heart
chr17_+_5915875 0.61 ENSDART00000184179
fibronectin type III domain containing 4b
chr3_-_55139127 0.60 ENSDART00000115324
hemoglobin, alpha embryonic 1.3
chr3_+_54047342 0.58 ENSDART00000178486
olfactomedin 2a
chr7_+_22543963 0.58 ENSDART00000101528
cholinergic receptor, nicotinic, beta 1 (muscle)
chr22_+_5106751 0.57 ENSDART00000138967
ataxia, cerebellar, Cayman type a
chr3_-_21061931 0.57 ENSDART00000036741
family with sequence similarity 57, member Ba
chr21_+_3093419 0.56 ENSDART00000162520
SHC adaptor protein 3
chr18_+_7345417 0.55 ENSDART00000041429
GLI pathogenesis-related 1b
chr16_+_31511739 0.53 ENSDART00000049420
N-myc downstream regulated 1b
chr6_+_10338554 0.52 ENSDART00000186936
cordon-bleu WH2 repeat protein-like 1a
chr3_-_18575868 0.50 ENSDART00000122968
aquaporin 8b
chr4_-_2162688 0.50 ENSDART00000148900
potassium voltage-gated channel, Shaw-related subfamily, member 2
chr21_+_29077509 0.49 ENSDART00000128561
endothelial cell surface expressed chemotaxis and apoptosis regulator
chr15_-_16323750 0.48 ENSDART00000028500
nucleoredoxin
chr14_-_4043818 0.47 ENSDART00000179870
sorting nexin 25
chr23_+_216012 0.47 ENSDART00000181115
ENSDART00000004678
ENSDART00000190439
ENSDART00000189322
si:ch73-162j3.4
chr4_-_11024767 0.46 ENSDART00000067261
ENSDART00000167631
transmembrane and tetratricopeptide repeat containing 2a
chr25_+_35502552 0.46 ENSDART00000189612
ENSDART00000058443
fin bud initiation factor a
chr9_+_307863 0.45 ENSDART00000163474
SH3 and cysteine rich domain 3
chr5_-_61588998 0.44 ENSDART00000050912
peroxisomal biogenesis factor 12
chr10_-_22918214 0.44 ENSDART00000163908
ribonuclease, RNase K b
chr8_+_8845932 0.43 ENSDART00000112028
si:ch211-180f4.1
chr23_+_35759843 0.42 ENSDART00000047082
ganglioside induced differentiation associated protein 1-like 1
chr13_+_30912117 0.41 ENSDART00000133138
dorsal root ganglia homeobox
chr20_-_18731268 0.41 ENSDART00000183893
ectonucleotide pyrophosphatase/phosphodiesterase 5
chr7_-_67842997 0.41 ENSDART00000169763
polyamine modulated factor 1 binding protein 1
chr24_-_30096666 0.41 ENSDART00000183285
phospholipid phosphatase related 4b
chr3_+_24482999 0.41 ENSDART00000059179
neuronal pentraxin receptor a
chr7_-_13884610 0.40 ENSDART00000006897
retinaldehyde binding protein 1a
chr21_-_45588720 0.40 ENSDART00000186642
ENSDART00000189531

chr13_-_25632756 0.39 ENSDART00000077627
ENSDART00000139237
ret proto-oncogene receptor tyrosine kinase
chr16_+_50755133 0.38 ENSDART00000029283
zgc:110372
chr10_-_2526526 0.38 ENSDART00000191726
ENSDART00000192767

chr1_+_45085194 0.38 ENSDART00000193863
si:ch211-151p13.8
chr10_-_25699454 0.38 ENSDART00000064376
superoxide dismutase 1, soluble
chr3_+_46479705 0.38 ENSDART00000181564
tyrosine kinase 2
chr12_+_48634927 0.37 ENSDART00000168441
zgc:165653
chr12_+_4225199 0.37 ENSDART00000042277
mitogen-activated protein kinase 7
chr25_+_37285737 0.37 ENSDART00000126879
transmembrane p24 trafficking protein 6
chr13_+_30912938 0.36 ENSDART00000190003
dorsal root ganglia homeobox
chr16_-_27640995 0.36 ENSDART00000019658
NAC alpha domain containing
chr19_+_33139164 0.36 ENSDART00000043039
family with sequence similarity 84, member B
chr21_+_27448856 0.36 ENSDART00000100784
complement factor b-like
chr9_-_23253870 0.35 ENSDART00000143657
ENSDART00000169911
aminocarboxymuconate semialdehyde decarboxylase
chr11_+_3254252 0.35 ENSDART00000123568
premelanosome protein a
chr17_-_52587598 0.35 ENSDART00000061497
si:ch211-173a9.6
chr9_-_53920959 0.34 ENSDART00000149618
midline 1
chr3_+_14317802 0.34 ENSDART00000162023
phospholipid phosphatase related 2a
chr7_+_58843700 0.34 ENSDART00000159500
ENSDART00000158436
lysophospholipase I
chr11_-_669558 0.34 ENSDART00000173450
peroxisome proliferator-activated receptor gamma
chr13_-_11667661 0.33 ENSDART00000102411
dynactin 1b
chr10_+_37182626 0.33 ENSDART00000137636
kinase suppressor of ras 1a
chr25_-_10564721 0.33 ENSDART00000154776
galanin/GMAP prepropeptide
chr7_-_35126374 0.32 ENSDART00000141211
hydroxysteroid (11-beta) dehydrogenase 2
chr19_+_310494 0.32 ENSDART00000053638
cathepsin S, ortholog 1
chr3_+_46479913 0.32 ENSDART00000149755
tyrosine kinase 2
chr12_+_2665081 0.31 ENSDART00000147532
retinol binding protein 3
chr5_+_9382301 0.31 ENSDART00000124017
UDP glucuronosyltransferase 2 family, polypeptide A7
chr19_+_46259619 0.31 ENSDART00000158032
glutamate receptor, ionotropic, N-methyl D-aspartate-associated protein 1a (glutamate binding)
chr21_-_40557281 0.31 ENSDART00000172327
TAO kinase 1b
chr5_-_5326010 0.30 ENSDART00000161946
pre-B-cell leukemia homeobox 3a
chr21_-_11996769 0.30 ENSDART00000143537
zgc:64106
chr11_-_669270 0.30 ENSDART00000172834
peroxisome proliferator-activated receptor gamma
chr5_+_9377005 0.30 ENSDART00000124924
UDP glucuronosyltransferase 2 family, polypeptide A7
chr16_+_14029283 0.30 ENSDART00000146165
ENSDART00000132075
RUN and SH3 domain containing 1
chr15_+_47386939 0.29 ENSDART00000128224

chr14_-_34633960 0.29 ENSDART00000128869
ENSDART00000179977
actin filament associated protein 1-like 1a
chr8_+_25299069 0.29 ENSDART00000114676
glutathione S-transferase mu tandem duplicate 2
chr22_-_26558166 0.29 ENSDART00000111125
GLIS family zinc finger 2a
chr4_+_12931763 0.28 ENSDART00000016382
wnt inhibitory factor 1
chr19_+_56351 0.28 ENSDART00000168334
collagen, type XIV, alpha 1b
chr8_-_7386978 0.28 ENSDART00000058321
LHFPL tetraspan subfamily member 4b
chr11_+_3254524 0.28 ENSDART00000159459
premelanosome protein a
chr21_+_1381276 0.27 ENSDART00000192907
transcription factor 4
chr3_+_25216790 0.27 ENSDART00000156544
C1q and TNF related 6a
chr8_-_46897734 0.27 ENSDART00000138125
hes family bHLH transcription factor 2, tandem duplicate 2
chr12_-_35393211 0.27 ENSDART00000137139
calcium/calmodulin-dependent protein kinase (CaM kinase) II gamma 1
chr9_+_55075526 0.27 ENSDART00000139555
ENSDART00000133864
G protein-coupled receptor 143
chr6_+_29923593 0.27 ENSDART00000169687
discs, large homolog 1 (Drosophila)
chr14_-_47882706 0.27 ENSDART00000188772
Rap guanine nucleotide exchange factor (GEF) 2
chr16_+_50741154 0.27 ENSDART00000101627
zgc:110372
chr25_-_10565006 0.27 ENSDART00000130608
ENSDART00000190212
galanin/GMAP prepropeptide
chr22_+_35275206 0.26 ENSDART00000112234
RUN domain and cysteine-rich domain containing, Beclin 1-interacting protein
chr16_-_35975254 0.26 ENSDART00000167537
eva-1 homolog Ba (C. elegans)
chr6_+_49082796 0.26 ENSDART00000182446
thyroid stimulating hormone, beta subunit, a
chr5_-_21044693 0.26 ENSDART00000140298
si:dkey-13n15.2
chr1_-_9104631 0.26 ENSDART00000146642
si:ch211-14k19.8
chr23_-_46217134 0.25 ENSDART00000189477
ENSDART00000168352

chr7_-_36358303 0.25 ENSDART00000130028
fat mass and obesity associated
chr19_-_9472893 0.25 ENSDART00000045565
ENSDART00000137505
vesicle-associated membrane protein 1
chr10_+_7182423 0.25 ENSDART00000186788
pleckstrin and Sec7 domain containing 3, like
chr2_-_15041846 0.25 ENSDART00000139050
si:dkey-10f21.4
chr4_-_4535189 0.25 ENSDART00000057519
zgc:194209
chr5_-_45651548 0.25 ENSDART00000097645
neuropeptide FF receptor 2a
chr24_-_37877743 0.24 ENSDART00000105658
transmembrane protein 204
chr4_+_8376362 0.24 ENSDART00000138653
ENSDART00000132647
ELKS/RAB6-interacting/CAST family member 1b
chr11_-_18799827 0.24 ENSDART00000185438
ENSDART00000189116
ENSDART00000180504
6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 2b
chr1_+_56229674 0.23 ENSDART00000127714
complement component c3a, duplicate 2
chr3_-_54544612 0.23 ENSDART00000018044
angiopoietin-like 6
chr21_+_22985078 0.23 ENSDART00000156491
lysophosphatidic acid receptor 6b
chr6_-_33707278 0.23 ENSDART00000188103
microtubule associated serine/threonine kinase 2
chr7_-_23848012 0.23 ENSDART00000146104
ENSDART00000175108
si:ch211-200p22.4
chr2_+_25378457 0.22 ENSDART00000089108
fibronectin type III domain containing 3Ba
chr24_-_41267184 0.22 ENSDART00000063504
xylulokinase homolog (H. influenzae)
chr14_+_7140997 0.22 ENSDART00000170994
ENSDART00000129898
cathepsin F
chr7_-_36358735 0.22 ENSDART00000188392
fat mass and obesity associated
chr4_+_10616626 0.22 ENSDART00000067251
ENSDART00000143690
cadherin-like and PC-esterase domain containing 1
chr7_+_39401388 0.22 ENSDART00000144750
troponin I type 2b (skeletal, fast), tandem duplicate 1
chr17_-_44584811 0.22 ENSDART00000165059
ENSDART00000165252
solute carrier family 35, member F4
chr14_+_23076207 0.21 ENSDART00000161628
ecto-NOX disulfide-thiol exchanger 2
chr13_+_30912385 0.21 ENSDART00000182642
dorsal root ganglia homeobox
chr15_+_25681044 0.21 ENSDART00000077853
hypermethylated in cancer 1
chr21_+_19635486 0.20 ENSDART00000185736
fibroblast growth factor 10a
chr12_+_316238 0.20 ENSDART00000187492
recoverin b
chr21_+_26991198 0.20 ENSDART00000065397
FK506 binding protein 2
chr22_+_1028724 0.20 ENSDART00000149625
si:ch73-352p18.4
chr14_+_36521553 0.20 ENSDART00000136233
si:dkey-237h12.3
chr22_+_12366516 0.19 ENSDART00000157802
R3H domain containing 1
chr23_-_28294763 0.19 ENSDART00000139537
zinc finger protein 385A
chr1_+_50976975 0.19 ENSDART00000022290
ENSDART00000140982
malate dehydrogenase 1Aa, NAD (soluble)
chr11_+_27364338 0.19 ENSDART00000186759
fibulin 2
chr13_-_25719628 0.18 ENSDART00000135383
si:dkey-192p21.6
chr17_-_3303805 0.18 ENSDART00000169136

chr14_+_30285613 0.18 ENSDART00000173090
microtubule associated tumor suppressor 1a
chr7_-_23777445 0.18 ENSDART00000173527
si:ch211-200p22.4
chr2_+_28889936 0.18 ENSDART00000078232
cadherin 10, type 2a (T2-cadherin)
chr14_+_39255437 0.18 ENSDART00000147443
diaphanous-related formin 2
chr15_-_21692630 0.18 ENSDART00000039865
succinate dehydrogenase complex, subunit D, integral membrane protein b
chr24_-_37877978 0.17 ENSDART00000128574
transmembrane protein 204
chr3_+_60007703 0.17 ENSDART00000157351
ENSDART00000153928
ENSDART00000155876
si:ch211-110e21.3
chr8_-_54304381 0.17 ENSDART00000184177
rhodopsin
chr9_-_21238159 0.17 ENSDART00000146764
ENSDART00000102143
COX17 cytochrome c oxidase copper chaperone
chr2_-_51095743 0.17 ENSDART00000184646
si:ch73-52e5.2
chr19_-_24443394 0.17 ENSDART00000090825
thrombospondin 3b
chr19_-_46957968 0.17 ENSDART00000043713
angiopoietin 1
chr19_+_37620342 0.17 ENSDART00000158960
thrombospondin, type I, domain containing 7Aa
chr15_-_32383529 0.17 ENSDART00000028349
complement component 4
chr5_-_8171625 0.17 ENSDART00000167643
solute carrier family 1 (glial high affinity glutamate transporter), member 3a
chr14_+_14225048 0.17 ENSDART00000168749
neuroligin 3a
chr15_+_29728377 0.16 ENSDART00000099958
zgc:153372
chr14_+_8328645 0.16 ENSDART00000127494
neuregulin 2b
chr17_+_24446353 0.16 ENSDART00000140467
UDP-glucose pyrophosphorylase 2b
chr6_-_32726848 0.16 ENSDART00000155294
zinc finger CCCH-type containing 3
chr19_-_24443867 0.16 ENSDART00000163763
ENSDART00000043133
thrombospondin 3b
chr8_-_14126646 0.16 ENSDART00000027225
biglycan a
chr18_+_5490668 0.16 ENSDART00000167035
muscle-specific beta 1 integrin binding protein 2
chr18_+_50278858 0.15 ENSDART00000014582
si:dkey-105e17.1
chr23_-_32892441 0.15 ENSDART00000147998
plexin A2
chr3_-_61592417 0.15 ENSDART00000155082
neuronal pentraxin 2a
chr5_+_37487687 0.15 ENSDART00000184659

chr4_+_5798223 0.15 ENSDART00000059440
si:ch73-352p4.8
chr18_+_48446704 0.15 ENSDART00000134817
Fli-1 proto-oncogene, ETS transcription factor a
chr12_-_6551681 0.15 ENSDART00000145413
si:ch211-253p2.2
chr11_-_37411492 0.15 ENSDART00000166468
ELKS/RAB6-interacting/CAST family member 2
chr25_-_19661198 0.15 ENSDART00000149641
ATPase plasma membrane Ca2+ transporting 1b
chr2_+_51028269 0.15 ENSDART00000161254
eukaryotic translation elongation factor 1 delta a (guanine nucleotide exchange protein)
chr17_-_37052622 0.15 ENSDART00000186408
DNA (cytosine-5-)-methyltransferase 3 alpha b
chr16_-_43065164 0.15 ENSDART00000149431
sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4Aa
chr24_-_28711176 0.14 ENSDART00000105753
olfactomedin 3a
chr12_+_40905427 0.14 ENSDART00000170526
ENSDART00000185771
ENSDART00000193945
cadherin 18
chr2_+_5948534 0.14 ENSDART00000124324
ENSDART00000176461
solute carrier family 1 (glutamate transporter), member 7a
chr20_+_1960092 0.14 ENSDART00000191892

chr8_+_25342896 0.14 ENSDART00000129032

chr23_+_45611649 0.14 ENSDART00000169521
doublecortin-like kinase 2b
chr12_+_4573696 0.14 ENSDART00000152534
si:dkey-94f20.4
chr14_+_14224730 0.14 ENSDART00000180112
ENSDART00000184891
ENSDART00000174760
neuroligin 3a
chr23_-_42093537 0.14 ENSDART00000122074
solute carrier family 1 (glutamate transporter), member 7b
chr23_+_16620801 0.14 ENSDART00000189859
ENSDART00000184578
syntaphilin b
chr16_+_50972803 0.13 ENSDART00000178189
si:dkeyp-97a10.2
chr2_-_6548838 0.13 ENSDART00000052419
regulator of G protein signaling 18
chr22_-_29586608 0.13 ENSDART00000059869
adrenoceptor alpha 2A
chr13_-_226393 0.13 ENSDART00000172677
reticulon 4b
chr8_+_7756893 0.13 ENSDART00000191894
FYVE, RhoGEF and PH domain containing 1
chr2_-_53896300 0.13 ENSDART00000161221
calcyphosine-like a
chr13_+_27314795 0.13 ENSDART00000128726
eukaryotic translation elongation factor 1 alpha 1a
chr14_-_30876708 0.13 ENSDART00000147597
ubiquitin-like 3b
chr6_+_19933763 0.13 ENSDART00000166192
phosphoinositide-3-kinase, regulatory subunit 5
chr22_+_15438872 0.13 ENSDART00000139800
glypican 5b
chr1_+_59538755 0.13 ENSDART00000166354
Sp6 transcription factor
chr3_+_14339728 0.13 ENSDART00000184127
phospholipid phosphatase related 2a

Network of associatons between targets according to the STRING database.

First level regulatory network of si:dkey-149i17.7_zic1

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.3 GO:0099509 regulation of presynaptic cytosolic calcium ion concentration(GO:0099509) regulation of long-term synaptic potentiation(GO:1900271)
0.2 0.6 GO:0097435 fibril organization(GO:0097435)
0.2 0.5 GO:0042245 RNA repair(GO:0042245)
0.1 0.6 GO:0019254 carnitine metabolic process, CoA-linked(GO:0019254)
0.1 0.4 GO:1901387 positive regulation of voltage-gated calcium channel activity(GO:1901387)
0.1 0.3 GO:0090219 negative regulation of phosphatidylinositol 3-kinase activity(GO:0043553) negative regulation of lipid kinase activity(GO:0090219)
0.1 0.4 GO:0014707 branchiomeric skeletal muscle development(GO:0014707) neural crest cell migration involved in autonomic nervous system development(GO:1901166)
0.1 0.5 GO:0032287 peripheral nervous system myelin maintenance(GO:0032287)
0.1 0.2 GO:0005997 xylulose metabolic process(GO:0005997)
0.1 0.8 GO:0032926 negative regulation of activin receptor signaling pathway(GO:0032926)
0.1 0.2 GO:0021557 oculomotor nerve development(GO:0021557)
0.1 0.4 GO:0019805 quinolinate biosynthetic process(GO:0019805) quinolinate metabolic process(GO:0046874)
0.1 0.2 GO:0018872 arsonoacetate metabolic process(GO:0018872)
0.1 1.1 GO:0007271 synaptic transmission, cholinergic(GO:0007271)
0.1 0.2 GO:0003403 optic vesicle formation(GO:0003403)
0.1 0.2 GO:0060437 lung growth(GO:0060437) secretion by lung epithelial cell involved in lung growth(GO:0061033)
0.0 0.3 GO:0034650 cortisol metabolic process(GO:0034650)
0.0 0.6 GO:0070328 acylglycerol homeostasis(GO:0055090) triglyceride homeostasis(GO:0070328)
0.0 0.2 GO:0032655 interleukin-12 production(GO:0032615) regulation of interleukin-12 production(GO:0032655)
0.0 0.5 GO:0035479 angioblast cell migration from lateral mesoderm to midline(GO:0035479)
0.0 0.2 GO:0006011 UDP-glucose metabolic process(GO:0006011)
0.0 0.2 GO:0007624 ultradian rhythm(GO:0007624)
0.0 0.2 GO:0048014 Tie signaling pathway(GO:0048014)
0.0 0.3 GO:0050848 regulation of calcium-mediated signaling(GO:0050848)
0.0 0.4 GO:0000303 response to superoxide(GO:0000303) response to oxygen radical(GO:0000305) removal of superoxide radicals(GO:0019430) cellular response to oxygen radical(GO:0071450) cellular response to superoxide(GO:0071451) cellular oxidant detoxification(GO:0098869) cellular detoxification(GO:1990748)
0.0 0.2 GO:0006107 oxaloacetate metabolic process(GO:0006107)
0.0 0.1 GO:0043455 regulation of secondary metabolic process(GO:0043455)
0.0 0.4 GO:0048790 maintenance of presynaptic active zone structure(GO:0048790) maintenance of synapse structure(GO:0099558)
0.0 0.1 GO:1901533 negative regulation of hematopoietic progenitor cell differentiation(GO:1901533)
0.0 0.2 GO:0006121 mitochondrial electron transport, succinate to ubiquinone(GO:0006121)
0.0 0.1 GO:0006740 NADPH regeneration(GO:0006740)
0.0 0.1 GO:0043383 negative T cell selection(GO:0043383)
0.0 0.3 GO:0097090 presynaptic membrane organization(GO:0097090) postsynaptic membrane assembly(GO:0097104) presynaptic membrane assembly(GO:0097105)
0.0 0.3 GO:1902108 regulation of mitochondrial membrane permeability involved in apoptotic process(GO:1902108)
0.0 0.6 GO:0015671 oxygen transport(GO:0015671) hydrogen peroxide catabolic process(GO:0042744)
0.0 0.1 GO:0051659 maintenance of mitochondrion location(GO:0051659)
0.0 0.1 GO:0071881 adenylate cyclase-inhibiting adrenergic receptor signaling pathway(GO:0071881)
0.0 0.3 GO:0002084 protein depalmitoylation(GO:0002084) macromolecule depalmitoylation(GO:0098734)
0.0 0.5 GO:0016558 protein import into peroxisome matrix(GO:0016558)
0.0 0.5 GO:0031397 negative regulation of protein ubiquitination(GO:0031397)
0.0 0.1 GO:0044034 viral genome replication(GO:0019079) negative stranded viral RNA replication(GO:0039689) viral RNA genome replication(GO:0039694) RNA replication(GO:0039703) multi-organism biosynthetic process(GO:0044034)
0.0 0.1 GO:1901006 ubiquinone-6 metabolic process(GO:1901004) ubiquinone-6 biosynthetic process(GO:1901006)
0.0 0.1 GO:0001774 microglial cell activation(GO:0001774)
0.0 0.3 GO:0090110 cargo loading into COPII-coated vesicle(GO:0090110)
0.0 0.2 GO:0006003 fructose 2,6-bisphosphate metabolic process(GO:0006003)
0.0 0.3 GO:0035493 SNARE complex assembly(GO:0035493)
0.0 0.1 GO:0090243 fibroblast growth factor receptor signaling pathway involved in somitogenesis(GO:0090243)
0.0 0.1 GO:2000725 regulation of cardiocyte differentiation(GO:1905207) regulation of cardiac muscle cell differentiation(GO:2000725)
0.0 0.4 GO:0007634 optokinetic behavior(GO:0007634)
0.0 1.0 GO:0006096 glycolytic process(GO:0006096)
0.0 0.1 GO:0034755 iron ion transmembrane transport(GO:0034755)
0.0 0.2 GO:0015014 heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process(GO:0015014)
0.0 0.4 GO:0016185 synaptic vesicle budding from presynaptic endocytic zone membrane(GO:0016185)
0.0 0.1 GO:0090386 phagosome maturation involved in apoptotic cell clearance(GO:0090386) phagolysosome assembly involved in apoptotic cell clearance(GO:0090387)
0.0 0.1 GO:0006842 tricarboxylic acid transport(GO:0006842) citrate transport(GO:0015746)
0.0 0.3 GO:1903845 negative regulation of transforming growth factor beta receptor signaling pathway(GO:0030512) negative regulation of cellular response to transforming growth factor beta stimulus(GO:1903845)
0.0 0.3 GO:2000134 negative regulation of cell cycle G1/S phase transition(GO:1902807) negative regulation of G1/S transition of mitotic cell cycle(GO:2000134)
0.0 0.3 GO:0007097 nuclear migration(GO:0007097) establishment of nucleus localization(GO:0040023)
0.0 0.1 GO:0042795 snRNA transcription from RNA polymerase II promoter(GO:0042795)
0.0 0.3 GO:0002574 thrombocyte differentiation(GO:0002574)
0.0 0.0 GO:0048677 axon extension involved in regeneration(GO:0048677) sprouting of injured axon(GO:0048682)
0.0 0.4 GO:0097194 execution phase of apoptosis(GO:0097194)
0.0 1.3 GO:0006865 amino acid transport(GO:0006865)
0.0 0.9 GO:0046839 phospholipid dephosphorylation(GO:0046839)
0.0 1.3 GO:0002088 lens development in camera-type eye(GO:0002088)
0.0 0.1 GO:2001239 histone dephosphorylation(GO:0016576) negative regulation of signal transduction in absence of ligand(GO:1901099) regulation of extrinsic apoptotic signaling pathway in absence of ligand(GO:2001239) negative regulation of extrinsic apoptotic signaling pathway in absence of ligand(GO:2001240)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.4 GO:1990415 Pex17p-Pex14p docking complex(GO:1990415) peroxisomal importomer complex(GO:1990429)
0.1 0.4 GO:0097224 sperm connecting piece(GO:0097224)
0.1 0.4 GO:0005854 nascent polypeptide-associated complex(GO:0005854)
0.1 1.3 GO:0043195 terminal bouton(GO:0043195)
0.0 0.6 GO:0031838 haptoglobin-hemoglobin complex(GO:0031838)
0.0 0.6 GO:0005892 acetylcholine-gated channel complex(GO:0005892)
0.0 0.4 GO:0098894 presynaptic endocytic zone(GO:0098833) presynaptic endocytic zone membrane(GO:0098835) extrinsic component of presynaptic membrane(GO:0098888) extrinsic component of presynaptic endocytic zone(GO:0098894)
0.0 0.2 GO:0045281 mitochondrial respiratory chain complex II, succinate dehydrogenase complex (ubiquinone)(GO:0005749) succinate dehydrogenase complex (ubiquinone)(GO:0045257) respiratory chain complex II(GO:0045273) succinate dehydrogenase complex(GO:0045281) fumarate reductase complex(GO:0045283)
0.0 0.4 GO:0030315 T-tubule(GO:0030315)
0.0 0.5 GO:0032809 neuronal cell body membrane(GO:0032809) cell body membrane(GO:0044298)
0.0 0.3 GO:0045009 melanosome membrane(GO:0033162) chitosome(GO:0045009)
0.0 0.6 GO:0048770 melanosome(GO:0042470) pigment granule(GO:0048770)
0.0 0.1 GO:0005853 eukaryotic translation elongation factor 1 complex(GO:0005853)
0.0 0.3 GO:0002102 podosome(GO:0002102)
0.0 0.1 GO:0071914 prominosome(GO:0071914)
0.0 0.4 GO:0098831 cytoskeleton of presynaptic active zone(GO:0048788) presynaptic active zone cytoplasmic component(GO:0098831)
0.0 0.1 GO:0045254 pyruvate dehydrogenase complex(GO:0045254)
0.0 0.3 GO:0035371 microtubule plus-end(GO:0035371)
0.0 0.3 GO:0030127 COPII vesicle coat(GO:0030127)
0.0 0.1 GO:0044295 axonal growth cone(GO:0044295)
0.0 0.3 GO:0031594 neuromuscular junction(GO:0031594)
0.0 0.1 GO:0090533 sodium:potassium-exchanging ATPase complex(GO:0005890) cation-transporting ATPase complex(GO:0090533)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.6 GO:0004466 long-chain-acyl-CoA dehydrogenase activity(GO:0004466)
0.2 1.0 GO:0004743 pyruvate kinase activity(GO:0004743)
0.1 0.4 GO:0008022 protein C-terminus binding(GO:0008022)
0.1 0.6 GO:0070644 vitamin D response element binding(GO:0070644)
0.1 0.5 GO:0047134 protein-disulfide reductase activity(GO:0047134)
0.1 0.5 GO:0035516 oxidative DNA demethylase activity(GO:0035516) DNA-N1-methyladenine dioxygenase activity(GO:0043734) RNA N6-methyladenosine dioxygenase activity(GO:1990931)
0.1 0.3 GO:0072545 tyrosine binding(GO:0072545)
0.1 0.7 GO:0005351 sugar:proton symporter activity(GO:0005351) cation:sugar symporter activity(GO:0005402) sucrose:proton symporter activity(GO:0008506) sucrose transmembrane transporter activity(GO:0008515) disaccharide transmembrane transporter activity(GO:0015154) oligosaccharide transmembrane transporter activity(GO:0015157)
0.1 0.6 GO:0016805 dipeptidase activity(GO:0016805)
0.1 0.5 GO:0015250 water channel activity(GO:0015250)
0.1 0.2 GO:0030791 arsenite methyltransferase activity(GO:0030791) methylarsonite methyltransferase activity(GO:0030792)
0.1 0.6 GO:0004309 exopolyphosphatase activity(GO:0004309)
0.0 0.6 GO:0031720 haptoglobin binding(GO:0031720)
0.0 0.4 GO:0016721 superoxide dismutase activity(GO:0004784) oxidoreductase activity, acting on superoxide radicals as acceptor(GO:0016721)
0.0 0.2 GO:0003983 UTP:glucose-1-phosphate uridylyltransferase activity(GO:0003983) UTP-monosaccharide-1-phosphate uridylyltransferase activity(GO:0051748)
0.0 0.8 GO:0048185 activin binding(GO:0048185)
0.0 0.2 GO:0030060 L-malate dehydrogenase activity(GO:0030060)
0.0 0.3 GO:0019841 retinol binding(GO:0019841)
0.0 0.2 GO:0016531 copper chaperone activity(GO:0016531)
0.0 0.1 GO:0008746 NAD(P)+ transhydrogenase activity(GO:0008746) oxidoreductase activity, acting on NAD(P)H, NAD(P) as acceptor(GO:0016652)
0.0 0.9 GO:0042577 lipid phosphatase activity(GO:0042577)
0.0 0.5 GO:0004169 dolichyl-phosphate-mannose-protein mannosyltransferase activity(GO:0004169)
0.0 0.1 GO:0017153 sodium:dicarboxylate symporter activity(GO:0017153)
0.0 0.4 GO:0005545 1-phosphatidylinositol binding(GO:0005545)
0.0 0.1 GO:0034185 apolipoprotein binding(GO:0034185)
0.0 0.1 GO:0008887 glycerate kinase activity(GO:0008887)
0.0 0.5 GO:0003785 actin monomer binding(GO:0003785)
0.0 0.1 GO:0005094 Rho GDP-dissociation inhibitor activity(GO:0005094)
0.0 0.2 GO:0016840 carbon-nitrogen lyase activity(GO:0016840)
0.0 0.1 GO:0004938 alpha2-adrenergic receptor activity(GO:0004938)
0.0 0.2 GO:0050262 ribosylnicotinamide kinase activity(GO:0050262)
0.0 0.4 GO:0098882 structural constituent of presynaptic active zone(GO:0098882)
0.0 0.5 GO:0022848 acetylcholine-gated cation channel activity(GO:0022848)
0.0 0.1 GO:0050211 procollagen galactosyltransferase activity(GO:0050211)
0.0 0.2 GO:0048039 ubiquinone binding(GO:0048039)
0.0 0.2 GO:0015016 [heparan sulfate]-glucosamine N-sulfotransferase activity(GO:0015016)
0.0 0.4 GO:0042043 neurexin family protein binding(GO:0042043)
0.0 0.2 GO:0003873 6-phosphofructo-2-kinase activity(GO:0003873)
0.0 0.2 GO:0005111 type 2 fibroblast growth factor receptor binding(GO:0005111)
0.0 1.3 GO:0005212 structural constituent of eye lens(GO:0005212)
0.0 0.2 GO:0070915 lysophosphatidic acid receptor activity(GO:0070915)
0.0 0.3 GO:0008474 palmitoyl-(protein) hydrolase activity(GO:0008474) palmitoyl hydrolase activity(GO:0098599)
0.0 0.1 GO:0031779 melanocortin receptor binding(GO:0031779)
0.0 0.1 GO:0005381 iron ion transmembrane transporter activity(GO:0005381)
0.0 0.3 GO:0033764 steroid dehydrogenase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor(GO:0033764)
0.0 0.8 GO:0015020 glucuronosyltransferase activity(GO:0015020)
0.0 0.1 GO:0051920 peroxiredoxin activity(GO:0051920)
0.0 0.1 GO:0015057 thrombin receptor activity(GO:0015057)
0.0 0.1 GO:0004738 pyruvate dehydrogenase activity(GO:0004738)
0.0 0.1 GO:0002161 aminoacyl-tRNA editing activity(GO:0002161)
0.0 1.2 GO:0019905 syntaxin binding(GO:0019905)
0.0 0.1 GO:0008118 N-acetyllactosaminide alpha-2,3-sialyltransferase activity(GO:0008118)
0.0 0.5 GO:0005251 delayed rectifier potassium channel activity(GO:0005251)
0.0 0.1 GO:0003886 DNA (cytosine-5-)-methyltransferase activity(GO:0003886)
0.0 0.4 GO:0004707 MAP kinase activity(GO:0004707)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.7 ST TYPE I INTERFERON PATHWAY Type I Interferon (alpha/beta IFN) Pathway
0.0 0.6 PID SYNDECAN 3 PATHWAY Syndecan-3-mediated signaling events
0.0 0.6 PID RXR VDR PATHWAY RXR and RAR heterodimerization with other nuclear receptor
0.0 0.7 PID MAPK TRK PATHWAY Trk receptor signaling mediated by the MAPK pathway
0.0 0.6 PID TRKR PATHWAY Neurotrophic factor-mediated Trk receptor signaling
0.0 0.3 PID WNT SIGNALING PATHWAY Wnt signaling network

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.7 REACTOME IL 6 SIGNALING Genes involved in Interleukin-6 signaling
0.0 0.6 REACTOME MITOCHONDRIAL FATTY ACID BETA OXIDATION Genes involved in Mitochondrial Fatty Acid Beta-Oxidation
0.0 0.4 REACTOME ERKS ARE INACTIVATED Genes involved in ERKs are inactivated
0.0 0.4 REACTOME SIGNAL ATTENUATION Genes involved in Signal attenuation
0.0 0.3 REACTOME ENOS ACTIVATION AND REGULATION Genes involved in eNOS activation and regulation
0.0 0.1 REACTOME GAP JUNCTION DEGRADATION Genes involved in Gap junction degradation
0.0 0.3 REACTOME TRYPTOPHAN CATABOLISM Genes involved in Tryptophan catabolism
0.0 0.3 REACTOME IONOTROPIC ACTIVITY OF KAINATE RECEPTORS Genes involved in Ionotropic activity of Kainate Receptors
0.0 0.2 REACTOME SEMA3A PLEXIN REPULSION SIGNALING BY INHIBITING INTEGRIN ADHESION Genes involved in SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion
0.0 0.5 REACTOME VOLTAGE GATED POTASSIUM CHANNELS Genes involved in Voltage gated Potassium channels
0.0 0.3 REACTOME PROTEOLYTIC CLEAVAGE OF SNARE COMPLEX PROTEINS Genes involved in Proteolytic cleavage of SNARE complex proteins
0.0 0.6 REACTOME NUCLEAR RECEPTOR TRANSCRIPTION PATHWAY Genes involved in Nuclear Receptor transcription pathway
0.0 0.2 REACTOME BILE SALT AND ORGANIC ANION SLC TRANSPORTERS Genes involved in Bile salt and organic anion SLC transporters
0.0 0.1 REACTOME AMINE LIGAND BINDING RECEPTORS Genes involved in Amine ligand-binding receptors