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PRJNA195909:zebrafish embryo and larva development
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Results for rx3
Z-value: 1.45
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Transcription factors associated with rx3
Activity-expression correlation:
| Gene | Promoter | Pearson corr. coef. | P-value | Plot |
|---|---|---|---|---|
| rx3 | dr11_v1_chr21_+_10756154_10756154 | -0.58 | 1.0e-01 | Click! |
| Promoter | Log-likelihood | Transcript | Gene | Gene Info |
|---|---|---|---|---|
| chr21_+_25777425 Show fit | 5.63 |
ENSDART00000021620
|
claudin d |
|
| chr10_-_21362071 Show fit | 5.30 |
ENSDART00000125167
|
avidin |
|
| chr10_-_21362320 Show fit | 5.21 |
ENSDART00000189789
|
avidin |
|
| chr18_-_40708537 Show fit | 4.94 |
ENSDART00000077577
|
si:ch211-132b12.8 |
|
| chr11_-_44801968 Show fit | 4.91 |
ENSDART00000161846
|
microtubule-associated protein 1 light chain 3 gamma |
|
| chr8_+_45334255 Show fit | 4.86 |
ENSDART00000126848
ENSDART00000134161 ENSDART00000142322 ENSDART00000145011 ENSDART00000183560 |
poly(A) binding protein, cytoplasmic 1-like |
|
| chr24_+_12835935 Show fit | 4.64 |
ENSDART00000114762
|
nanog homeobox |
|
| chr9_-_35633827 Show fit | 4.62 |
ENSDART00000077745
|
zona pellucida glycoprotein 2, like 1 |
|
| chr10_-_34002185 Show fit | 3.93 |
ENSDART00000046599
|
zygote arrest 1-like |
|
| chr20_-_23426339 Show fit | 3.86 |
ENSDART00000004625
|
zygote arrest 1 |
Network of associatons between targets according to the STRING database.
First level regulatory network of rx3
Gene Ontology Analysis
Gene overrepresentation in biological process category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.3 | 5.8 | GO:0035803 | binding of sperm to zona pellucida(GO:0007339) egg coat formation(GO:0035803) regulation of acrosome reaction(GO:0060046) positive regulation of acrosome reaction(GO:2000344) |
| 0.3 | 5.8 | GO:0051445 | regulation of meiotic cell cycle(GO:0051445) |
| 0.1 | 5.7 | GO:0060968 | regulation of gene silencing(GO:0060968) |
| 1.1 | 5.6 | GO:0016338 | calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules(GO:0016338) |
| 0.1 | 5.4 | GO:0017148 | negative regulation of translation(GO:0017148) |
| 0.3 | 4.9 | GO:0006995 | cellular response to nitrogen starvation(GO:0006995) cellular response to nitrogen levels(GO:0043562) |
| 0.3 | 3.9 | GO:0035493 | SNARE complex assembly(GO:0035493) |
| 1.2 | 3.6 | GO:0097067 | cellular response to thyroid hormone stimulus(GO:0097067) |
| 0.1 | 3.2 | GO:0042761 | very long-chain fatty acid biosynthetic process(GO:0042761) |
| 0.0 | 2.9 | GO:0046854 | phosphatidylinositol phosphorylation(GO:0046854) |
Gene overrepresentation in cellular component category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.2 | 6.0 | GO:0010494 | cytoplasmic stress granule(GO:0010494) |
| 0.2 | 6.0 | GO:0000421 | autophagosome membrane(GO:0000421) |
| 0.2 | 5.8 | GO:0043186 | P granule(GO:0043186) |
| 0.0 | 5.6 | GO:0070160 | bicellular tight junction(GO:0005923) occluding junction(GO:0070160) |
| 0.0 | 5.3 | GO:0031012 | extracellular matrix(GO:0031012) |
| 0.0 | 3.9 | GO:0000323 | lytic vacuole(GO:0000323) |
| 0.1 | 3.6 | GO:0016592 | mediator complex(GO:0016592) |
| 0.6 | 1.9 | GO:0097189 | apoptotic body(GO:0097189) |
| 0.0 | 1.7 | GO:0005834 | heterotrimeric G-protein complex(GO:0005834) |
| 0.1 | 1.6 | GO:0032420 | stereocilium(GO:0032420) |
Gene overrepresentation in molecular function category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 2.1 | 10.5 | GO:0009374 | biotin binding(GO:0009374) |
| 0.0 | 9.8 | GO:0042802 | identical protein binding(GO:0042802) |
| 0.0 | 9.3 | GO:0003729 | mRNA binding(GO:0003729) poly(A) RNA binding(GO:0044822) |
| 0.1 | 6.9 | GO:0003724 | RNA helicase activity(GO:0003724) |
| 0.3 | 5.8 | GO:0032190 | acrosin binding(GO:0032190) |
| 0.3 | 4.9 | GO:0008266 | poly(U) RNA binding(GO:0008266) |
| 0.1 | 4.9 | GO:0031625 | ubiquitin protein ligase binding(GO:0031625) |
| 0.0 | 3.9 | GO:0000149 | SNARE binding(GO:0000149) |
| 0.7 | 3.6 | GO:0042809 | vitamin D receptor binding(GO:0042809) |
| 0.0 | 3.2 | GO:0016627 | oxidoreductase activity, acting on the CH-CH group of donors(GO:0016627) |
Gene overrepresentation in curated gene sets: canonical pathways category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 1.9 | WNT SIGNALING | Genes related to Wnt-mediated signal transduction |
| 0.0 | 1.4 | PID WNT NONCANONICAL PATHWAY | Noncanonical Wnt signaling pathway |
| 0.0 | 1.4 | NABA COLLAGENS | Genes encoding collagen proteins |
| 0.0 | 1.4 | PID ERBB1 DOWNSTREAM PATHWAY | ErbB1 downstream signaling |
| 0.1 | 1.3 | PID TCR CALCIUM PATHWAY | Calcium signaling in the CD4+ TCR pathway |
| 0.0 | 1.1 | ST TUMOR NECROSIS FACTOR PATHWAY | Tumor Necrosis Factor Pathway. |
| 0.0 | 0.6 | PID PRL SIGNALING EVENTS PATHWAY | Signaling events mediated by PRL |
| 0.0 | 0.4 | PID HNF3A PATHWAY | FOXA1 transcription factor network |
Gene overrepresentation in curated gene sets: REACTOME pathways category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.2 | 2.5 | REACTOME BILE SALT AND ORGANIC ANION SLC TRANSPORTERS | Genes involved in Bile salt and organic anion SLC transporters |
| 0.0 | 1.4 | REACTOME COLLAGEN FORMATION | Genes involved in Collagen formation |
| 0.1 | 1.1 | REACTOME MRNA DECAY BY 5 TO 3 EXORIBONUCLEASE | Genes involved in mRNA Decay by 5' to 3' Exoribonuclease |
| 0.0 | 0.9 | REACTOME METABOLISM OF VITAMINS AND COFACTORS | Genes involved in Metabolism of vitamins and cofactors |
| 0.0 | 0.6 | REACTOME SYNTHESIS OF PE | Genes involved in Synthesis of PE |
| 0.0 | 0.6 | REACTOME EFFECTS OF PIP2 HYDROLYSIS | Genes involved in Effects of PIP2 hydrolysis |
| 0.0 | 0.6 | REACTOME MITOCHONDRIAL PROTEIN IMPORT | Genes involved in Mitochondrial Protein Import |
| 0.0 | 0.4 | REACTOME INSULIN SYNTHESIS AND PROCESSING | Genes involved in Insulin Synthesis and Processing |
| 0.0 | 0.2 | REACTOME RETROGRADE NEUROTROPHIN SIGNALLING | Genes involved in Retrograde neurotrophin signalling |