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PRJNA195909:zebrafish embryo and larva development

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Results for runx1

Z-value: 1.34

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Transcription factors associated with runx1

Gene Symbol Gene ID Gene Info
ENSDARG00000087646 RUNX family transcription factor 1

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
runx1dr11_v1_chr1_-_1402303_1402303-0.264.9e-01Click!

Activity profile of runx1 motif

Sorted Z-values of runx1 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr24_-_9989634 1.50 ENSDART00000115275
zgc:152652
chr11_-_44999858 1.26 ENSDART00000167759
ENSDART00000126845
LIM-domain binding 1b
chr3_+_28576173 1.21 ENSDART00000151189
septin 12
chr4_+_77973876 1.08 ENSDART00000057423
telomeric repeat binding factor a
chr15_-_26636826 1.05 ENSDART00000087632
solute carrier family 47 (multidrug and toxin extrusion), member 4
chr3_+_15809098 0.83 ENSDART00000183023
phosphatase, orphan 1
chr2_+_36898982 0.82 ENSDART00000084859
RAB GTPase activating protein 1-like 2
chr21_+_45659525 0.82 ENSDART00000160391
solute carrier family 22 (organic cation/carnitine transporter), member 5
chr6_+_34868156 0.80 ENSDART00000149364
interleukin 23 receptor
chr18_+_22109379 0.79 ENSDART00000147230
zgc:158868
chr4_-_49069087 0.78 ENSDART00000150622
si:ch211-234c11.3
chr5_+_36513605 0.76 ENSDART00000013590
wingless-type MMTV integration site family, member 11
chr7_-_24995631 0.68 ENSDART00000173955
ENSDART00000173791
REST corepressor 2
chr13_-_43108693 0.68 ENSDART00000164439
si:ch211-106f21.1
chr6_-_2162446 0.65 ENSDART00000171265
transglutaminase 5, like
chr20_+_98179 0.65 ENSDART00000022725
si:ch1073-155h21.1
chr3_-_5433392 0.64 ENSDART00000159308
tripartite motif containing 35-7
chr9_+_50175366 0.62 ENSDART00000170352
cordon-bleu WH2 repeat protein-like 1b
chr15_-_25571865 0.62 ENSDART00000077836
matrix metallopeptidase 20b (enamelysin)
chr15_+_39977461 0.61 ENSDART00000063786
calcium binding protein 39
chr4_+_63088692 0.59 ENSDART00000168872
zgc:173714
chr7_+_3872189 0.58 ENSDART00000064221
si:dkey-88n24.5
chr24_+_30695120 0.58 ENSDART00000178649
zgc:174719
chr10_+_38643304 0.56 ENSDART00000067447
matrix metallopeptidase 30
chr7_+_15329819 0.56 ENSDART00000006018
mesoderm posterior aa
chr8_+_45294767 0.56 ENSDART00000191527
ubiquitin associated protein 2b
chr1_-_12126535 0.56 ENSDART00000164817
ENSDART00000015251
microsomal triglyceride transfer protein
chr25_-_17368231 0.55 ENSDART00000189291
cytochrome P450, family 2, subfamily X, polypeptide 6
chr1_+_54650048 0.55 ENSDART00000141207
si:ch211-202h22.7
chr3_-_79366 0.55 ENSDART00000114289
zgc:165518
chr24_-_7826489 0.53 ENSDART00000112777
si:dkey-197c15.6
chr4_-_38877924 0.53 ENSDART00000177741
zinc finger protein 1127
chr5_+_61475451 0.51 ENSDART00000163444
leucine-rich repeats and WD repeat domain containing 1
chr8_-_37249813 0.51 ENSDART00000098634
ENSDART00000140233
ENSDART00000061328
RNA binding motif protein 39b
chr16_+_1383914 0.51 ENSDART00000185089
ceramide synthase 2b
chr13_+_24263049 0.51 ENSDART00000135992
ENSDART00000088005
ATP-binding cassette, sub-family B (MDR/TAP), member 10
chr15_-_17025212 0.50 ENSDART00000014465
huntingtin interacting protein 1
chr15_+_22435460 0.50 ENSDART00000031976
transmembrane protein 136a
chr3_-_31879201 0.49 ENSDART00000076189
zgc:171779
chr19_-_3874986 0.49 ENSDART00000161830
thyroid hormone receptor associated protein 3b
chr8_-_32803227 0.48 ENSDART00000110079
zgc:194839
chr3_-_19367081 0.48 ENSDART00000191369
sphingosine-1-phosphate receptor 5a
chr21_-_11632403 0.45 ENSDART00000171708
ENSDART00000138619
ENSDART00000136308
ENSDART00000144770
calpastatin
chr2_+_35880600 0.45 ENSDART00000004277
laminin, gamma 1
chr4_+_63790028 0.44 ENSDART00000160964
si:dkey-92j16.2
chr21_+_29179887 0.44 ENSDART00000161941
si:ch211-57b15.1
chr12_+_10443785 0.44 ENSDART00000029133
SNU13 homolog, small nuclear ribonucleoprotein b (U4/U6.U5)
chr23_-_29357764 0.44 ENSDART00000156512
si:ch211-129o18.4
chr16_-_30584279 0.44 ENSDART00000077226
melanocortin 5b receptor
chr23_+_10347851 0.44 ENSDART00000127667
keratin 18
chr16_+_13860299 0.43 ENSDART00000121998
glutamate-rich WD repeat containing 1
chr14_-_26498196 0.43 ENSDART00000054175
ENSDART00000145625
ENSDART00000183347
ENSDART00000191084
ENSDART00000191143
SMAD family member 5
chr13_+_18533005 0.43 ENSDART00000136024
finTRIM family, member 14-like
chr24_-_9979342 0.42 ENSDART00000138576
ENSDART00000191206
zgc:171977
chr24_-_9991153 0.42 ENSDART00000137794
ENSDART00000106252
ENSDART00000188309
ENSDART00000188266
ENSDART00000188660
ENSDART00000185713
ENSDART00000179773
zgc:152652
chr2_+_48288461 0.42 ENSDART00000141495
hes family bHLH transcription factor 6
chr2_-_22569488 0.42 ENSDART00000158608

chr22_+_9922301 0.41 ENSDART00000105924
bloody fingers
chr7_-_17337233 0.41 ENSDART00000050236
ENSDART00000102141
novel immune-type receptor 8
chr4_+_38170708 0.41 ENSDART00000168900
zinc finger protein 1071
chr10_+_2742499 0.41 ENSDART00000122847
G protein-coupled receptor kinase 5
chr13_-_6081803 0.40 ENSDART00000099224
deltaD
chr8_-_49207319 0.40 ENSDART00000022870
family with sequence similarity 110, member A
chr18_+_31073265 0.40 ENSDART00000023539
cytochrome b-245, alpha polypeptide
chr6_-_57476465 0.40 ENSDART00000128065
DEAD (Asp-Glu-Ala-Asp) box polypeptide 27
chr1_-_39895859 0.40 ENSDART00000135791
ENSDART00000035739
transmembrane protein 134
chr8_-_47844456 0.40 ENSDART00000145429
si:dkeyp-104h9.5
chr18_-_2639351 0.40 ENSDART00000168106
RELT, TNF receptor
chr4_-_9867476 0.39 ENSDART00000091630
F-box protein, helicase, 18
chr16_-_51254694 0.39 ENSDART00000148894
serpin peptidase inhibitor, clade B (ovalbumin), member 14
chr1_-_55750208 0.39 ENSDART00000142244
DnaJ (Hsp40) homolog, subfamily B, member 1b
chr3_+_60761811 0.39 ENSDART00000053482
TSEN54 tRNA splicing endonuclease subunit
chr17_+_691453 0.39 ENSDART00000159271
Fanconi anemia, complementation group M
chr2_-_21786826 0.38 ENSDART00000016208
chromodomain helicase DNA binding protein 7
chr6_-_2154137 0.38 ENSDART00000162656
transglutaminase 5, like
chr1_+_12195700 0.38 ENSDART00000040307
tudor domain containing 7 a
chr25_-_22889519 0.38 ENSDART00000128250
MOB kinase activator 2a
chr19_+_20801060 0.38 ENSDART00000143457
carnosine dipeptidase 2
chr6_+_30668098 0.37 ENSDART00000112294
tetratricopeptide repeat domain 22
chr6_-_12270226 0.37 ENSDART00000180473
plakophilin 4
chr24_+_31361407 0.37 ENSDART00000162668
cAMP responsive element modulator b
chr1_-_45213565 0.37 ENSDART00000145757
DEAD (Asp-Glu-Ala-Asp) box polypeptide 39Aa
chr15_-_41677689 0.37 ENSDART00000187063
splA/ryanodine receptor domain and SOCS box containing 4b
chr11_+_7580079 0.37 ENSDART00000091550
ENSDART00000193223
ENSDART00000193386
adhesion G protein-coupled receptor L2a
chr5_+_63302660 0.37 ENSDART00000142131
si:ch73-376l24.2
chr24_-_30843250 0.37 ENSDART00000162920
polypyrimidine tract binding protein 2a
chr17_+_23311377 0.37 ENSDART00000128073
protein phosphatase 1, regulatory subunit 3Ca
chr6_+_38626926 0.36 ENSDART00000190339
ATPase phospholipid transporting 10A
chr13_-_24263682 0.36 ENSDART00000176800
URB2 ribosome biogenesis 2 homolog (S. cerevisiae)
chr15_+_24572926 0.36 ENSDART00000155636
ENSDART00000187800
dehydrogenase/reductase (SDR family) member 13b
chr4_-_9867785 0.36 ENSDART00000133169
ENSDART00000185905
ENSDART00000185204
ENSDART00000180753
F-box protein, helicase, 18
chr14_-_46198373 0.36 ENSDART00000031640
ENSDART00000132966
zgc:113425
chr1_-_25177086 0.35 ENSDART00000144711
ENSDART00000177225
transmembrane protein 154
chr10_-_3332362 0.35 ENSDART00000007577
ENSDART00000055140
torsin family 4, member Aa
chr20_-_23852174 0.35 ENSDART00000122414
si:dkey-15j16.6
chr1_+_39859782 0.35 ENSDART00000149984
interferon regulatory factor 2a
chr3_+_23092762 0.35 ENSDART00000142884
ENSDART00000024136
guanine nucleotide binding protein (G protein), gamma transducing activity polypeptide 2a
chr21_-_44081540 0.35 ENSDART00000130833

chr25_-_14637660 0.35 ENSDART00000143666
neuron navigator 2b
chr4_-_4261673 0.35 ENSDART00000150694
CD9 molecule b
chr4_+_34126849 0.34 ENSDART00000162442
si:ch211-223g7.6
chr5_+_36439405 0.34 ENSDART00000102973
ectodysplasin A
chr5_+_22836364 0.34 ENSDART00000131885
si:ch211-26b3.2
chr20_+_54034677 0.34 ENSDART00000173317
ENSDART00000173215
si:dkey-241l7.2
chr19_-_8798178 0.33 ENSDART00000188232
ceramide synthase 2a
chr14_+_34501245 0.33 ENSDART00000131424
lymphocyte cytosolic protein 2b
chr7_-_26262978 0.33 ENSDART00000137769
adaptor-related protein complex 1, sigma 1 subunit
chr2_-_44282796 0.33 ENSDART00000163040
ENSDART00000166923
ENSDART00000056372
ENSDART00000109251
ENSDART00000132682
myelin protein zero
chr17_+_24687338 0.33 ENSDART00000135794
selenoprotein N
chr3_-_48259289 0.33 ENSDART00000160717
zinc finger protein 750
chr16_+_32082359 0.33 ENSDART00000140794
ENSDART00000137029
PRP31 pre-mRNA processing factor 31 homolog (yeast)
chr9_+_38457806 0.33 ENSDART00000142512
minichromosome maintenance complex component 3 associated protein
chr23_+_17509794 0.33 ENSDART00000148457
GID complex subunit 8 homolog b (S. cerevisiae)
chr7_-_73854476 0.33 ENSDART00000186481
zgc:173552
chr17_+_51744450 0.32 ENSDART00000190955
ENSDART00000149807
ornithine decarboxylase 1
chr16_+_46410520 0.32 ENSDART00000131072
rapunzel 2
chr23_-_16682186 0.32 ENSDART00000020810
syndecan binding protein (syntenin) 2
chr6_-_21830405 0.32 ENSDART00000151803
ENSDART00000113497
SET domain containing 5
chr1_-_34335752 0.32 ENSDART00000140157
si:dkey-24h22.5
chr23_-_19484160 0.32 ENSDART00000137026
family with sequence similarity 208, member Ab
chr5_+_34622320 0.32 ENSDART00000141338
ectodermal-neural cortex 1
chr2_+_20793982 0.32 ENSDART00000014785
proteoglycan 4a
chr19_-_19442983 0.32 ENSDART00000052649
sb:cb649
chr8_+_3434146 0.32 ENSDART00000164426
cytosolic thiouridylase subunit 1 homolog (S. pombe)
chr5_-_22600881 0.32 ENSDART00000176442
non-POU domain containing, octamer-binding
chr9_+_23770666 0.32 ENSDART00000182493
si:ch211-219a4.3
chr21_-_14826066 0.32 ENSDART00000067001
nucleolar complex associated 4 homolog
chr8_+_47099033 0.32 ENSDART00000142979
Rho guanine nucleotide exchange factor (GEF) 16
chr5_+_57337630 0.31 ENSDART00000012586
solute carrier family 31 (copper transporter), member 1
chr16_+_32082547 0.31 ENSDART00000190122
PRP31 pre-mRNA processing factor 31 homolog (yeast)
chr4_+_8532580 0.31 ENSDART00000162065
wingless-type MMTV integration site family, member 5b
chr2_-_30055432 0.31 ENSDART00000056747
sonic hedgehog b
chr3_+_18807524 0.31 ENSDART00000055757
transportin 2 (importin 3, karyopherin beta 2b)
chr2_-_58919975 0.31 ENSDART00000114286
SURP and G patch domain containing 1
chr2_+_3044992 0.31 ENSDART00000020463
zgc:63882
chr20_+_54027943 0.31 ENSDART00000153400
ENSDART00000152961
si:dkey-241l7.3
chr4_-_52504961 0.31 ENSDART00000163123
si:dkey-78o7.3
chr10_+_32066537 0.30 ENSDART00000124166
si:dkey-250d21.1
chr21_+_25198637 0.30 ENSDART00000164972
si:dkey-183i3.6
chr12_-_26851726 0.30 ENSDART00000047724
zinc finger E-box binding homeobox 1b
chr5_+_25585869 0.30 ENSDART00000138060
si:dkey-229d2.7
chr2_+_29884363 0.30 ENSDART00000139247
si:ch211-207d6.2
chr3_-_19368435 0.30 ENSDART00000132987
sphingosine-1-phosphate receptor 5a
chr6_-_55399214 0.30 ENSDART00000168367
cathepsin A
chr1_-_40015782 0.30 ENSDART00000157425
ENSDART00000159238
cyclin-dependent kinase 2 associated protein 2
chr18_+_40354998 0.30 ENSDART00000098791
ENSDART00000049171
sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6D, like
chr5_-_29152457 0.29 ENSDART00000078469
NADPH oxidase activator 1
chr3_-_32362872 0.29 ENSDART00000035545
ENSDART00000012630
protein arginine methyltransferase 1
chr5_+_28497956 0.29 ENSDART00000191935
notochord formation related
chr4_+_13909398 0.29 ENSDART00000187959
ENSDART00000184926
periphilin 1
chr9_+_38458193 0.29 ENSDART00000008053
minichromosome maintenance complex component 3 associated protein
chr15_-_15469079 0.29 ENSDART00000132637
ENSDART00000004220
RAB34, member RAS oncogene family a
chr3_+_43774369 0.29 ENSDART00000157964
zinc finger CCCH-type containing 7A
chr21_-_30082414 0.29 ENSDART00000157307
ENSDART00000155188
cyclin J-like
chr12_-_20616160 0.29 ENSDART00000105362
sorting nexin 11
chr19_-_18152407 0.29 ENSDART00000193264
ENSDART00000016135
nuclear factor, erythroid 2-like 3
chr19_-_22328154 0.29 ENSDART00000090464
si:ch73-196l6.5
chr10_+_10738880 0.29 ENSDART00000004181
solute carrier family 27 (fatty acid transporter), member 4
chr15_-_14884332 0.29 ENSDART00000165237
si:ch211-24o8.4
chr22_-_38801510 0.29 ENSDART00000140764
si:ch211-262h13.3
chr4_+_30718997 0.29 ENSDART00000190901

chr6_-_138392 0.28 ENSDART00000148974
kelch-like ECH-associated protein 1b
chr14_+_24845941 0.28 ENSDART00000187513
Rho guanine nucleotide exchange factor (GEF) 37
chr4_+_37952218 0.28 ENSDART00000186865
si:dkeyp-82b4.2
chr22_-_621888 0.28 ENSDART00000135829
serine/arginine-rich splicing factor 3b
chr23_+_5104743 0.28 ENSDART00000123191
ubiquitin-conjugating enzyme E2T (putative)
chr9_-_40683722 0.28 ENSDART00000141979
ENSDART00000181228
BRCA1 associated RING domain 1
chr17_-_14817458 0.28 ENSDART00000155907
ENSDART00000156476
nidogen 2a (osteonidogen)
chr8_-_49304602 0.28 ENSDART00000147020
prickle homolog 3
chr8_-_37249991 0.27 ENSDART00000189275
ENSDART00000178556
RNA binding motif protein 39b
chr8_+_37749263 0.27 ENSDART00000108556
ENSDART00000147942
nucleophosmin/nucleoplasmin, 2a
chr18_+_44795711 0.27 ENSDART00000110229
ENSDART00000188262
ENSDART00000139526
family with sequence similarity 118, member B
chr4_-_12795436 0.27 ENSDART00000131026
ENSDART00000075127
beta-2-microglobulin
chr9_-_54344405 0.27 ENSDART00000182939

chr5_+_61508418 0.27 ENSDART00000023676
branched chain ketoacid dehydrogenase kinase
chr13_+_11829072 0.27 ENSDART00000079356
ENSDART00000170160
suppressor of fused homolog (Drosophila)
chr24_+_19518570 0.27 ENSDART00000056081
sulfatase 1
chr6_-_27108844 0.27 ENSDART00000073883
deoxythymidylate kinase (thymidylate kinase)
chr6_-_138603 0.27 ENSDART00000148911
kelch-like ECH-associated protein 1b
chr10_+_15608326 0.27 ENSDART00000188770
zinc finger, AN1-type domain 5b
chr19_-_8926575 0.27 ENSDART00000080897
regulation of nuclear pre-mRNA domain containing 2a
chr2_-_1364678 0.27 ENSDART00000011919
ENSDART00000164674
synovial sarcoma translocation, chromosome 18 (H. sapiens)
chr11_+_37720552 0.27 ENSDART00000050296
ENSDART00000172867
small nuclear ribonucleoprotein polypeptide E
chr4_-_60312069 0.26 ENSDART00000167207
si:dkey-248e17.4
chr17_-_42568498 0.26 ENSDART00000014296
forkhead box A2
chr4_+_72235562 0.26 ENSDART00000168547
si:cabz01071912.2
chr19_+_27859546 0.26 ENSDART00000161908
NOP2/Sun RNA methyltransferase family, member 2
chr2_+_49864219 0.26 ENSDART00000187744
ribosomal protein L37
chr6_-_45869127 0.26 ENSDART00000062459
ENSDART00000180563
RNA binding motif protein 19
chr8_+_41038141 0.26 ENSDART00000075620
glycerol-3-phosphate acyltransferase 2, mitochondrial
chr5_+_13373593 0.26 ENSDART00000051668
ENSDART00000183883
chemokine (C-C motif) ligand 19a, tandem duplicate 2
chr3_+_37197686 0.26 ENSDART00000151144
formin-like 1a
chr3_+_49074008 0.26 ENSDART00000168864
zgc:112146
chr1_+_8534698 0.26 ENSDART00000021504
Smith-Magenis syndrome chromosome region, candidate 8b
chr3_-_57762247 0.26 ENSDART00000156522
calcium activated nucleotidase 1a
chr8_-_16515127 0.26 ENSDART00000146469
ENSDART00000132681
tetratricopeptide repeat domain 39A
chr9_+_30112423 0.26 ENSDART00000112398
ENSDART00000013591
trk-fused gene
chr15_+_42235449 0.26 ENSDART00000114801
ENSDART00000182053
sphingosine-1-phosphate phosphatase 2
chr3_-_8285123 0.26 ENSDART00000158699
ENSDART00000138588
tripartite motif containing 35-9
chr14_-_22495604 0.26 ENSDART00000137167
si:ch211-107m4.1

Network of associatons between targets according to the STRING database.

First level regulatory network of runx1

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.1 GO:0032207 regulation of telomere maintenance via recombination(GO:0032207) negative regulation of telomere maintenance via recombination(GO:0032208)
0.2 0.2 GO:0046833 regulation of nucleobase-containing compound transport(GO:0032239) positive regulation of nucleobase-containing compound transport(GO:0032241) positive regulation of nucleocytoplasmic transport(GO:0046824) regulation of RNA export from nucleus(GO:0046831) positive regulation of RNA export from nucleus(GO:0046833)
0.1 0.8 GO:0000244 spliceosomal tri-snRNP complex assembly(GO:0000244)
0.1 0.4 GO:0000379 tRNA-type intron splice site recognition and cleavage(GO:0000379)
0.1 0.5 GO:0071169 establishment of protein localization to chromosome(GO:0070199) establishment of protein localization to chromatin(GO:0071169)
0.1 0.6 GO:0097186 amelogenesis(GO:0097186)
0.1 0.5 GO:0046385 pyrimidine deoxyribonucleotide biosynthetic process(GO:0009221) 2'-deoxyribonucleotide biosynthetic process(GO:0009265) deoxyribose phosphate biosynthetic process(GO:0046385)
0.1 0.8 GO:0015697 quaternary ammonium group transport(GO:0015697)
0.1 0.8 GO:0001579 medium-chain fatty acid transport(GO:0001579)
0.1 0.6 GO:0097101 blood vessel endothelial cell fate specification(GO:0097101)
0.1 0.4 GO:1990167 protein K27-linked deubiquitination(GO:1990167)
0.1 0.3 GO:0034398 telomere localization(GO:0034397) telomere tethering at nuclear periphery(GO:0034398) meiotic telomere tethering at nuclear periphery(GO:0044821) meiotic telomere clustering(GO:0045141) meiotic attachment of telomere to nuclear envelope(GO:0070197) chromosome localization to nuclear envelope involved in homologous chromosome segregation(GO:0090220) chromosome attachment to the nuclear envelope(GO:0097240)
0.1 0.7 GO:0042554 superoxide anion generation(GO:0042554)
0.1 0.1 GO:0045002 double-strand break repair via single-strand annealing(GO:0045002)
0.1 0.3 GO:1990120 messenger ribonucleoprotein complex assembly(GO:1990120)
0.1 0.3 GO:0045668 negative regulation of osteoblast differentiation(GO:0045668)
0.1 0.2 GO:0050968 chemosensory behavior(GO:0007635) detection of chemical stimulus involved in sensory perception of pain(GO:0050968)
0.1 0.3 GO:0034969 histone arginine methylation(GO:0034969)
0.1 0.2 GO:0006295 nucleotide-excision repair, DNA incision, 3'-to lesion(GO:0006295)
0.1 0.5 GO:0010172 embryonic body morphogenesis(GO:0010172)
0.1 0.3 GO:1904590 regulation of protein import into nucleus(GO:0042306) negative regulation of protein import into nucleus(GO:0042308) negative regulation of nucleocytoplasmic transport(GO:0046823) negative regulation of protein localization to nucleus(GO:1900181) regulation of protein import(GO:1904589) negative regulation of protein import(GO:1904590)
0.1 0.2 GO:0035973 aggrephagy(GO:0035973)
0.1 0.5 GO:0097341 inhibition of cysteine-type endopeptidase activity(GO:0097340) zymogen inhibition(GO:0097341)
0.1 0.4 GO:0031061 negative regulation of histone methylation(GO:0031061)
0.1 0.2 GO:0003408 optic cup formation involved in camera-type eye development(GO:0003408) spinal cord association neuron specification(GO:0021519)
0.1 0.4 GO:0043137 DNA replication, removal of RNA primer(GO:0043137)
0.1 0.3 GO:0035434 copper ion transmembrane transport(GO:0035434)
0.1 0.6 GO:0045003 double-strand break repair via synthesis-dependent strand annealing(GO:0045003)
0.1 0.3 GO:0070587 regulation of cell-cell adhesion involved in gastrulation(GO:0070587)
0.1 0.3 GO:0097355 protein localization to heterochromatin(GO:0097355)
0.1 0.4 GO:0021523 somatic motor neuron differentiation(GO:0021523)
0.1 0.1 GO:0033212 iron assimilation(GO:0033212)
0.1 0.2 GO:0051876 pigment granule dispersal(GO:0051876)
0.1 0.2 GO:0036228 protein targeting to nuclear inner membrane(GO:0036228) protein localization to nuclear envelope(GO:0090435)
0.1 0.2 GO:1990519 pyrimidine nucleotide transport(GO:0006864) mitochondrial pyrimidine nucleotide import(GO:1990519)
0.1 0.6 GO:0071379 cellular response to prostaglandin stimulus(GO:0071379)
0.1 0.3 GO:0030575 nuclear body organization(GO:0030575) Cajal body organization(GO:0030576)
0.1 0.2 GO:0031120 snRNA pseudouridine synthesis(GO:0031120)
0.1 0.2 GO:0008356 asymmetric cell division(GO:0008356)
0.1 0.3 GO:0032447 tRNA wobble position uridine thiolation(GO:0002143) protein urmylation(GO:0032447)
0.1 0.3 GO:0032289 central nervous system myelin formation(GO:0032289)
0.1 0.3 GO:1901098 positive regulation of autophagosome maturation(GO:1901098)
0.1 0.3 GO:0003348 cardiac endothelial cell differentiation(GO:0003348) endocardial cell differentiation(GO:0060956)
0.0 0.2 GO:0060784 regulation of cell proliferation involved in tissue homeostasis(GO:0060784)
0.0 0.2 GO:2000767 positive regulation of cytoplasmic translation(GO:2000767)
0.0 0.3 GO:0032218 riboflavin transport(GO:0032218)
0.0 0.8 GO:0031297 replication fork processing(GO:0031297)
0.0 0.2 GO:0010133 proline catabolic process to glutamate(GO:0010133)
0.0 0.2 GO:0051645 Golgi localization(GO:0051645) maintenance of centrosome location(GO:0051661)
0.0 0.6 GO:0006363 termination of RNA polymerase I transcription(GO:0006363)
0.0 0.1 GO:0007571 age-dependent general metabolic decline(GO:0007571)
0.0 0.4 GO:0006465 signal peptide processing(GO:0006465)
0.0 0.1 GO:0000066 mitochondrial ornithine transport(GO:0000066) mitochondrial L-ornithine transmembrane transport(GO:1990575)
0.0 0.2 GO:1902373 negative regulation of mRNA catabolic process(GO:1902373) regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:2000622) negative regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:2000623)
0.0 0.4 GO:0000491 small nucleolar ribonucleoprotein complex assembly(GO:0000491)
0.0 0.2 GO:1904182 regulation of pyruvate dehydrogenase activity(GO:1904182) positive regulation of pyruvate dehydrogenase activity(GO:1904184)
0.0 0.2 GO:1901842 regulation of high voltage-gated calcium channel activity(GO:1901841) negative regulation of high voltage-gated calcium channel activity(GO:1901842)
0.0 0.2 GO:0000393 spliceosomal conformational changes to generate catalytic conformation(GO:0000393)
0.0 1.0 GO:0070167 regulation of bone mineralization(GO:0030500) regulation of biomineral tissue development(GO:0070167)
0.0 0.6 GO:2000223 regulation of BMP signaling pathway involved in heart jogging(GO:2000223)
0.0 0.3 GO:1990511 piRNA biosynthetic process(GO:1990511)
0.0 0.4 GO:0050962 detection of light stimulus involved in visual perception(GO:0050908) detection of light stimulus involved in sensory perception(GO:0050962)
0.0 0.3 GO:0033387 putrescine biosynthetic process from ornithine(GO:0033387)
0.0 0.3 GO:0009312 oligosaccharide biosynthetic process(GO:0009312)
0.0 0.1 GO:2000382 positive regulation of mesoderm development(GO:2000382)
0.0 0.1 GO:0046654 tetrahydrofolate biosynthetic process(GO:0046654)
0.0 0.2 GO:0045736 negative regulation of cyclin-dependent protein serine/threonine kinase activity(GO:0045736) negative regulation of cyclin-dependent protein kinase activity(GO:1904030)
0.0 0.4 GO:0030719 P granule organization(GO:0030719)
0.0 0.3 GO:2000036 regulation of stem cell population maintenance(GO:2000036)
0.0 0.1 GO:0070358 actin polymerization-dependent cell motility(GO:0070358)
0.0 0.1 GO:1905048 regulation of metallopeptidase activity(GO:1905048)
0.0 0.2 GO:0048743 positive regulation of skeletal muscle fiber development(GO:0048743)
0.0 0.3 GO:0021910 smoothened signaling pathway involved in ventral spinal cord patterning(GO:0021910) regulation of myotome development(GO:2000290)
0.0 0.2 GO:0034720 histone H3-K4 demethylation(GO:0034720)
0.0 0.3 GO:0051279 regulation of calcium ion transport into cytosol(GO:0010522) regulation of release of sequestered calcium ion into cytosol(GO:0051279)
0.0 0.2 GO:0045899 regulation of RNA polymerase II transcriptional preinitiation complex assembly(GO:0045898) positive regulation of RNA polymerase II transcriptional preinitiation complex assembly(GO:0045899)
0.0 0.2 GO:2000105 positive regulation of DNA-dependent DNA replication(GO:2000105)
0.0 0.4 GO:0046548 retinal rod cell development(GO:0046548)
0.0 0.3 GO:0006616 SRP-dependent cotranslational protein targeting to membrane, translocation(GO:0006616)
0.0 0.2 GO:0016266 O-glycan processing(GO:0016266)
0.0 0.4 GO:1902254 negative regulation of intrinsic apoptotic signaling pathway by p53 class mediator(GO:1902254)
0.0 0.4 GO:0009303 rRNA transcription(GO:0009303)
0.0 0.3 GO:0048208 vesicle targeting, rough ER to cis-Golgi(GO:0048207) COPII vesicle coating(GO:0048208)
0.0 0.1 GO:0042304 regulation of fatty acid biosynthetic process(GO:0042304)
0.0 0.2 GO:0000270 peptidoglycan metabolic process(GO:0000270) peptidoglycan catabolic process(GO:0009253)
0.0 0.5 GO:0051897 positive regulation of protein kinase B signaling(GO:0051897)
0.0 0.3 GO:0003428 growth plate cartilage morphogenesis(GO:0003422) chondrocyte intercalation involved in growth plate cartilage morphogenesis(GO:0003428)
0.0 0.1 GO:0002566 somatic diversification of immune receptors via somatic mutation(GO:0002566) pyrimidine dimer repair(GO:0006290) somatic hypermutation of immunoglobulin genes(GO:0016446)
0.0 0.1 GO:0006178 guanine salvage(GO:0006178) GMP salvage(GO:0032263) guanine biosynthetic process(GO:0046099)
0.0 0.2 GO:0060965 negative regulation of posttranscriptional gene silencing(GO:0060149) negative regulation of gene silencing by miRNA(GO:0060965) negative regulation of gene silencing by RNA(GO:0060967) 3'-UTR-mediated mRNA stabilization(GO:0070935)
0.0 1.0 GO:0006406 mRNA export from nucleus(GO:0006406) mRNA-containing ribonucleoprotein complex export from nucleus(GO:0071427)
0.0 0.4 GO:0045292 mRNA cis splicing, via spliceosome(GO:0045292)
0.0 0.2 GO:2001032 regulation of double-strand break repair via nonhomologous end joining(GO:2001032)
0.0 0.2 GO:0097241 hematopoietic stem cell migration to bone marrow(GO:0097241)
0.0 0.2 GO:2001270 negative regulation of execution phase of apoptosis(GO:1900118) regulation of cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:2001270) negative regulation of cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:2001271)
0.0 0.2 GO:0006348 chromatin silencing at telomere(GO:0006348)
0.0 0.2 GO:0090385 phagosome-lysosome fusion(GO:0090385)
0.0 0.1 GO:0030219 megakaryocyte differentiation(GO:0030219)
0.0 0.3 GO:0045824 negative regulation of innate immune response(GO:0045824)
0.0 0.3 GO:0051865 protein autoubiquitination(GO:0051865)
0.0 0.2 GO:0006621 protein retention in ER lumen(GO:0006621)
0.0 0.4 GO:0044818 mitotic G2/M transition checkpoint(GO:0044818)
0.0 0.2 GO:0050909 sensory perception of taste(GO:0050909)
0.0 1.4 GO:0016575 histone deacetylation(GO:0016575)
0.0 0.2 GO:0006267 pre-replicative complex assembly involved in nuclear cell cycle DNA replication(GO:0006267) pre-replicative complex assembly(GO:0036388) pre-replicative complex assembly involved in cell cycle DNA replication(GO:1902299)
0.0 0.2 GO:0090497 mesenchymal cell migration(GO:0090497)
0.0 0.2 GO:0045050 protein insertion into ER membrane by stop-transfer membrane-anchor sequence(GO:0045050)
0.0 0.1 GO:0021588 cerebellum formation(GO:0021588)
0.0 0.5 GO:0034453 microtubule anchoring(GO:0034453)
0.0 0.7 GO:0030574 collagen catabolic process(GO:0030574) multicellular organism catabolic process(GO:0044243)
0.0 0.3 GO:0035196 production of miRNAs involved in gene silencing by miRNA(GO:0035196)
0.0 0.1 GO:0048739 cardiac muscle fiber development(GO:0048739)
0.0 0.4 GO:0032467 positive regulation of cytokinesis(GO:0032467)
0.0 0.5 GO:0043967 histone H4 acetylation(GO:0043967)
0.0 0.5 GO:0000387 spliceosomal snRNP assembly(GO:0000387)
0.0 0.6 GO:0016925 protein sumoylation(GO:0016925)
0.0 0.6 GO:0000470 maturation of LSU-rRNA(GO:0000470)
0.0 0.1 GO:0010801 regulation of peptidyl-threonine phosphorylation(GO:0010799) negative regulation of peptidyl-threonine phosphorylation(GO:0010801) regulation of protein deacetylation(GO:0090311)
0.0 0.1 GO:0001955 blood vessel maturation(GO:0001955)
0.0 0.1 GO:1902902 negative regulation of autophagosome maturation(GO:1901097) negative regulation of autophagosome assembly(GO:1902902)
0.0 0.1 GO:0001709 cell fate determination(GO:0001709)
0.0 0.1 GO:0001514 selenocysteine incorporation(GO:0001514) translational readthrough(GO:0006451)
0.0 0.1 GO:0042795 snRNA transcription from RNA polymerase II promoter(GO:0042795)
0.0 0.1 GO:0010972 negative regulation of G2/M transition of mitotic cell cycle(GO:0010972)
0.0 0.1 GO:0031643 positive regulation of myelination(GO:0031643)
0.0 0.1 GO:1902946 protein localization to early endosome(GO:1902946)
0.0 0.1 GO:0048011 neurotrophin TRK receptor signaling pathway(GO:0048011)
0.0 0.6 GO:0060037 pharyngeal system development(GO:0060037)
0.0 0.2 GO:0042509 tyrosine phosphorylation of STAT protein(GO:0007260) regulation of tyrosine phosphorylation of STAT protein(GO:0042509) positive regulation of tyrosine phosphorylation of STAT protein(GO:0042531)
0.0 0.1 GO:0034334 adherens junction maintenance(GO:0034334)
0.0 0.2 GO:0050714 positive regulation of protein secretion(GO:0050714)
0.0 0.1 GO:0048172 regulation of short-term neuronal synaptic plasticity(GO:0048172)
0.0 0.2 GO:0014036 neural crest cell fate commitment(GO:0014034) neural crest cell fate specification(GO:0014036)
0.0 0.0 GO:0061341 non-canonical Wnt signaling pathway involved in heart development(GO:0061341)
0.0 0.3 GO:0008354 germ cell migration(GO:0008354)
0.0 0.3 GO:0035269 protein O-linked mannosylation(GO:0035269)
0.0 0.1 GO:0042760 peroxisomal long-chain fatty acid import(GO:0015910) very long-chain fatty acid catabolic process(GO:0042760)
0.0 1.0 GO:0046513 ceramide biosynthetic process(GO:0046513)
0.0 0.1 GO:0032986 nucleosome disassembly(GO:0006337) chromatin disassembly(GO:0031498) protein-DNA complex disassembly(GO:0032986)
0.0 0.2 GO:0050829 defense response to Gram-negative bacterium(GO:0050829)
0.0 0.4 GO:0048263 determination of dorsal identity(GO:0048263)
0.0 0.1 GO:0006369 termination of RNA polymerase II transcription(GO:0006369)
0.0 0.2 GO:0010738 regulation of protein kinase A signaling(GO:0010738)
0.0 0.2 GO:0006689 ganglioside metabolic process(GO:0001573) ganglioside catabolic process(GO:0006689)
0.0 0.0 GO:0070914 UV-damage excision repair(GO:0070914)
0.0 0.1 GO:0016559 peroxisome fission(GO:0016559) mitochondrial fragmentation involved in apoptotic process(GO:0043653)
0.0 0.5 GO:0001878 response to yeast(GO:0001878)
0.0 0.2 GO:0090503 RNA phosphodiester bond hydrolysis, exonucleolytic(GO:0090503)
0.0 0.7 GO:0006606 protein import into nucleus(GO:0006606) protein targeting to nucleus(GO:0044744) single-organism nuclear import(GO:1902593)
0.0 0.1 GO:0017196 N-terminal peptidyl-methionine acetylation(GO:0017196)
0.0 0.2 GO:0002098 tRNA wobble uridine modification(GO:0002098)
0.0 0.3 GO:0034472 snRNA 3'-end processing(GO:0034472)
0.0 0.3 GO:0000184 nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:0000184)
0.0 0.2 GO:0060088 auditory receptor cell stereocilium organization(GO:0060088)
0.0 0.6 GO:0042129 regulation of T cell proliferation(GO:0042129)
0.0 0.1 GO:0048730 epidermis morphogenesis(GO:0048730)
0.0 0.1 GO:0006098 pentose-phosphate shunt(GO:0006098)
0.0 0.5 GO:0010906 regulation of glucose metabolic process(GO:0010906)
0.0 0.0 GO:0010812 negative regulation of cell-substrate adhesion(GO:0010812)
0.0 0.0 GO:0090230 regulation of centromere complex assembly(GO:0090230) regulation of kinetochore assembly(GO:0090234)
0.0 0.1 GO:0007197 adenylate cyclase-inhibiting G-protein coupled acetylcholine receptor signaling pathway(GO:0007197)
0.0 0.5 GO:0000079 regulation of cyclin-dependent protein serine/threonine kinase activity(GO:0000079) regulation of cyclin-dependent protein kinase activity(GO:1904029)
0.0 0.1 GO:0035094 response to nicotine(GO:0035094)
0.0 0.2 GO:0070989 oxidative demethylation(GO:0070989)
0.0 0.2 GO:0009409 response to cold(GO:0009409)
0.0 0.1 GO:0035283 central nervous system segmentation(GO:0035283) brain segmentation(GO:0035284)
0.0 0.1 GO:1902766 skeletal muscle satellite cell migration(GO:1902766)
0.0 0.2 GO:0002574 thrombocyte differentiation(GO:0002574)
0.0 0.1 GO:0061647 histone H3-K9 methylation(GO:0051567) histone H3-K9 modification(GO:0061647) heterochromatin organization(GO:0070828)
0.0 0.1 GO:0030309 poly-N-acetyllactosamine metabolic process(GO:0030309) poly-N-acetyllactosamine biosynthetic process(GO:0030311)
0.0 0.2 GO:0007205 protein kinase C-activating G-protein coupled receptor signaling pathway(GO:0007205)
0.0 0.1 GO:0071763 nuclear membrane organization(GO:0071763)
0.0 0.2 GO:0051568 histone H3-K4 methylation(GO:0051568)
0.0 0.1 GO:0006614 SRP-dependent cotranslational protein targeting to membrane(GO:0006614)
0.0 0.0 GO:0034134 toll-like receptor 2 signaling pathway(GO:0034134)
0.0 0.1 GO:0032515 negative regulation of phosphoprotein phosphatase activity(GO:0032515)
0.0 0.1 GO:0031048 chromatin silencing by small RNA(GO:0031048)
0.0 0.2 GO:0006303 double-strand break repair via nonhomologous end joining(GO:0006303)
0.0 0.1 GO:0044154 histone H3-K14 acetylation(GO:0044154)
0.0 0.3 GO:0048264 determination of ventral identity(GO:0048264)
0.0 0.1 GO:0097369 sodium ion import(GO:0097369) sodium ion import across plasma membrane(GO:0098719) sodium ion import into cell(GO:1990118)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.5 GO:0034709 methylosome(GO:0034709)
0.1 0.5 GO:0098890 extrinsic component of postsynaptic membrane(GO:0098890)
0.1 0.6 GO:0070390 transcription export complex 2(GO:0070390)
0.1 0.4 GO:0031510 SUMO activating enzyme complex(GO:0031510)
0.1 0.3 GO:0030689 Noc complex(GO:0030689)
0.1 0.4 GO:0000214 tRNA-intron endonuclease complex(GO:0000214)
0.1 0.6 GO:0071005 U2-type precatalytic spliceosome(GO:0071005)
0.1 1.3 GO:0070187 telosome(GO:0070187)
0.1 0.7 GO:0043020 NADPH oxidase complex(GO:0043020)
0.1 0.3 GO:0042382 paraspeckles(GO:0042382)
0.1 0.6 GO:0016234 inclusion body(GO:0016234)
0.1 0.2 GO:0033065 Rad51C-XRCC3 complex(GO:0033065)
0.1 0.2 GO:0043614 multi-eIF complex(GO:0043614)
0.1 0.4 GO:0031428 box C/D snoRNP complex(GO:0031428)
0.1 0.3 GO:0035301 Hedgehog signaling complex(GO:0035301)
0.1 0.3 GO:1990316 ATG1/ULK1 kinase complex(GO:1990316)
0.1 0.2 GO:0097124 cyclin A2-CDK2 complex(GO:0097124)
0.1 0.2 GO:0097255 R2TP complex(GO:0097255)
0.1 0.2 GO:0071556 integral component of cytoplasmic side of endoplasmic reticulum membrane(GO:0071458) integral component of lumenal side of endoplasmic reticulum membrane(GO:0071556) lumenal side of endoplasmic reticulum membrane(GO:0098553)
0.1 0.2 GO:0031213 RSF complex(GO:0031213)
0.1 0.3 GO:0070876 SOSS complex(GO:0070876)
0.1 0.2 GO:0000818 nuclear MIS12/MIND complex(GO:0000818)
0.0 0.4 GO:0044613 nuclear pore central transport channel(GO:0044613)
0.0 0.2 GO:0044326 dendritic spine neck(GO:0044326) dendritic filopodium(GO:1902737)
0.0 0.2 GO:0071006 U2-type catalytic step 1 spliceosome(GO:0071006) catalytic step 1 spliceosome(GO:0071012)
0.0 0.3 GO:0042612 MHC class I protein complex(GO:0042612)
0.0 0.3 GO:0048500 signal recognition particle, endoplasmic reticulum targeting(GO:0005786) signal recognition particle(GO:0048500)
0.0 0.1 GO:0000333 telomerase catalytic core complex(GO:0000333)
0.0 0.5 GO:0000808 origin recognition complex(GO:0000808) nuclear origin of replication recognition complex(GO:0005664)
0.0 0.2 GO:0031429 box H/ACA snoRNP complex(GO:0031429) box H/ACA RNP complex(GO:0072588)
0.0 0.1 GO:0042719 mitochondrial intermembrane space protein transporter complex(GO:0042719) mitochondrial inner membrane protein insertion complex(GO:0042721)
0.0 0.1 GO:0005787 signal peptidase complex(GO:0005787)
0.0 0.2 GO:0031313 extrinsic component of endosome membrane(GO:0031313)
0.0 0.2 GO:0005826 actomyosin contractile ring(GO:0005826)
0.0 0.3 GO:0070531 BRCA1-A complex(GO:0070531)
0.0 0.6 GO:0044666 MLL3/4 complex(GO:0044666)
0.0 0.5 GO:0043209 myelin sheath(GO:0043209)
0.0 0.2 GO:0033557 Slx1-Slx4 complex(GO:0033557)
0.0 0.4 GO:1990589 ATF4-CREB1 transcription factor complex(GO:1990589)
0.0 0.1 GO:0032301 MutSalpha complex(GO:0032301)
0.0 0.3 GO:0030015 CCR4-NOT core complex(GO:0030015)
0.0 0.1 GO:0031417 NatC complex(GO:0031417)
0.0 0.1 GO:0032584 growth cone membrane(GO:0032584)
0.0 0.1 GO:0008091 spectrin(GO:0008091)
0.0 0.1 GO:0034657 GID complex(GO:0034657)
0.0 0.1 GO:0005673 transcription factor TFIIE complex(GO:0005673)
0.0 0.2 GO:0034518 RNA cap binding complex(GO:0034518)
0.0 0.2 GO:0005671 Ada2/Gcn5/Ada3 transcription activator complex(GO:0005671)
0.0 0.2 GO:0031616 spindle pole centrosome(GO:0031616)
0.0 0.4 GO:0035267 NuA4 histone acetyltransferase complex(GO:0035267) H4/H2A histone acetyltransferase complex(GO:0043189) H4 histone acetyltransferase complex(GO:1902562)
0.0 0.4 GO:0071144 SMAD2-SMAD3 protein complex(GO:0071144)
0.0 0.2 GO:0070449 elongin complex(GO:0070449)
0.0 0.8 GO:0017053 transcriptional repressor complex(GO:0017053)
0.0 0.8 GO:0005940 septin ring(GO:0005940) septin complex(GO:0031105) septin cytoskeleton(GO:0032156)
0.0 0.2 GO:0005682 U5 snRNP(GO:0005682)
0.0 0.1 GO:0005953 CAAX-protein geranylgeranyltransferase complex(GO:0005953)
0.0 0.1 GO:0072487 MSL complex(GO:0072487)
0.0 0.2 GO:0030688 preribosome, small subunit precursor(GO:0030688)
0.0 0.3 GO:0015030 Cajal body(GO:0015030)
0.0 0.3 GO:0031680 G-protein beta/gamma-subunit complex(GO:0031680)
0.0 0.2 GO:0008540 proteasome regulatory particle, base subcomplex(GO:0008540)
0.0 0.2 GO:0000940 condensed chromosome outer kinetochore(GO:0000940)
0.0 0.1 GO:0005697 telomerase holoenzyme complex(GO:0005697)
0.0 0.2 GO:0071007 U2-type catalytic step 2 spliceosome(GO:0071007)
0.0 0.2 GO:0071013 catalytic step 2 spliceosome(GO:0071013)
0.0 0.9 GO:0000118 histone deacetylase complex(GO:0000118)
0.0 0.2 GO:0031211 serine C-palmitoyltransferase complex(GO:0017059) endoplasmic reticulum palmitoyltransferase complex(GO:0031211)
0.0 1.6 GO:0016607 nuclear speck(GO:0016607)
0.0 0.2 GO:0046540 U4/U6 x U5 tri-snRNP complex(GO:0046540)
0.0 0.2 GO:0071339 MLL1/2 complex(GO:0044665) MLL1 complex(GO:0071339)
0.0 0.2 GO:0072546 ER membrane protein complex(GO:0072546)
0.0 0.2 GO:0048188 Set1C/COMPASS complex(GO:0048188)
0.0 0.2 GO:0048179 activin receptor complex(GO:0048179)
0.0 0.3 GO:0032039 integrator complex(GO:0032039)
0.0 0.2 GO:0042555 MCM complex(GO:0042555)
0.0 0.4 GO:0010494 cytoplasmic stress granule(GO:0010494)
0.0 0.1 GO:0005655 nucleolar ribonuclease P complex(GO:0005655)
0.0 0.1 GO:0030126 COPI vesicle coat(GO:0030126)
0.0 0.1 GO:0005784 Sec61 translocon complex(GO:0005784)
0.0 0.1 GO:0016586 RSC complex(GO:0016586)
0.0 0.2 GO:1990907 beta-catenin-TCF complex(GO:1990907)
0.0 0.2 GO:0005689 U12-type spliceosomal complex(GO:0005689)
0.0 0.1 GO:0016012 sarcoglycan complex(GO:0016012)
0.0 0.1 GO:0030991 intraciliary transport particle A(GO:0030991)
0.0 0.0 GO:0000110 nucleotide-excision repair factor 1 complex(GO:0000110)
0.0 0.1 GO:0030014 CCR4-NOT complex(GO:0030014)
0.0 0.6 GO:0005788 endoplasmic reticulum lumen(GO:0005788)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 1.3 GO:0030274 LIM domain binding(GO:0030274)
0.1 1.1 GO:0098505 G-rich strand telomeric DNA binding(GO:0098505)
0.1 0.6 GO:1904121 phosphatidylethanolamine transporter activity(GO:1904121)
0.1 0.8 GO:0015651 quaternary ammonium group transmembrane transporter activity(GO:0015651)
0.1 0.3 GO:0045545 syndecan binding(GO:0045545)
0.1 0.4 GO:0019948 SUMO activating enzyme activity(GO:0019948)
0.1 0.3 GO:0009041 uridylate kinase activity(GO:0009041)
0.1 0.7 GO:0038036 sphingosine-1-phosphate receptor activity(GO:0038036)
0.1 0.4 GO:0008821 crossover junction endodeoxyribonuclease activity(GO:0008821)
0.1 0.4 GO:0070573 metallodipeptidase activity(GO:0070573)
0.1 0.5 GO:0000400 four-way junction DNA binding(GO:0000400)
0.1 0.3 GO:0016427 tRNA (cytosine) methyltransferase activity(GO:0016427)
0.1 1.0 GO:0042910 xenobiotic transporter activity(GO:0042910)
0.1 0.5 GO:0010859 calcium-dependent cysteine-type endopeptidase inhibitor activity(GO:0010859)
0.1 0.3 GO:0005375 copper ion transmembrane transporter activity(GO:0005375)
0.1 0.3 GO:0030942 endoplasmic reticulum signal peptide binding(GO:0030942)
0.1 0.2 GO:0016436 rRNA (uridine) methyltransferase activity(GO:0016436)
0.1 0.4 GO:0031957 very long-chain fatty acid-CoA ligase activity(GO:0031957)
0.1 0.2 GO:0070259 tyrosyl-DNA phosphodiesterase activity(GO:0070259)
0.1 0.2 GO:0016300 tRNA (uracil) methyltransferase activity(GO:0016300)
0.1 0.2 GO:0030623 U5 snRNA binding(GO:0030623)
0.1 0.3 GO:0004185 serine-type carboxypeptidase activity(GO:0004185)
0.1 0.4 GO:0035613 RNA stem-loop binding(GO:0035613)
0.1 0.2 GO:0004657 proline dehydrogenase activity(GO:0004657)
0.1 0.5 GO:0043325 phosphatidylinositol-3,4-bisphosphate binding(GO:0043325)
0.1 0.2 GO:0015218 pyrimidine nucleotide transmembrane transporter activity(GO:0015218)
0.1 0.4 GO:0070034 telomerase RNA binding(GO:0070034)
0.1 0.4 GO:0004523 RNA-DNA hybrid ribonuclease activity(GO:0004523)
0.0 0.2 GO:0043139 5'-3' DNA helicase activity(GO:0043139)
0.0 0.2 GO:0008745 N-acetylmuramoyl-L-alanine amidase activity(GO:0008745)
0.0 0.7 GO:0050291 sphingosine N-acyltransferase activity(GO:0050291)
0.0 0.2 GO:0043140 ATP-dependent 3'-5' DNA helicase activity(GO:0043140) single-stranded DNA-dependent ATP-dependent 3'-5' DNA helicase activity(GO:1990518)
0.0 0.1 GO:0004345 glucose-6-phosphate dehydrogenase activity(GO:0004345)
0.0 0.4 GO:0004977 melanocortin receptor activity(GO:0004977)
0.0 0.3 GO:0032217 riboflavin transporter activity(GO:0032217)
0.0 0.1 GO:0000217 DNA secondary structure binding(GO:0000217)
0.0 0.8 GO:0043138 3'-5' DNA helicase activity(GO:0043138)
0.0 0.2 GO:0001875 lipopolysaccharide receptor activity(GO:0001875) signaling pattern recognition receptor activity(GO:0008329)
0.0 0.7 GO:0032453 histone demethylase activity (H3-K4 specific)(GO:0032453)
0.0 0.2 GO:0004385 guanylate kinase activity(GO:0004385)
0.0 0.2 GO:0004741 [pyruvate dehydrogenase (lipoamide)] phosphatase activity(GO:0004741)
0.0 0.2 GO:0004949 cannabinoid receptor activity(GO:0004949)
0.0 0.1 GO:0015086 cadmium ion transmembrane transporter activity(GO:0015086)
0.0 1.2 GO:0043539 protein serine/threonine kinase activator activity(GO:0043539)
0.0 0.5 GO:0008327 methyl-CpG binding(GO:0008327)
0.0 0.3 GO:0004586 ornithine decarboxylase activity(GO:0004586)
0.0 0.3 GO:0005113 patched binding(GO:0005113)
0.0 0.1 GO:0043621 protein self-association(GO:0043621)
0.0 0.1 GO:0001160 transcription termination site sequence-specific DNA binding(GO:0001147) transcription termination site DNA binding(GO:0001160)
0.0 0.3 GO:0004740 pyruvate dehydrogenase (acetyl-transferring) kinase activity(GO:0004740)
0.0 0.3 GO:0004366 glycerol-3-phosphate O-acyltransferase activity(GO:0004366)
0.0 0.3 GO:0016176 superoxide-generating NADPH oxidase activator activity(GO:0016176)
0.0 0.2 GO:0004861 cyclin-dependent protein serine/threonine kinase inhibitor activity(GO:0004861)
0.0 0.2 GO:0035252 UDP-xylosyltransferase activity(GO:0035252)
0.0 0.1 GO:0016494 C-X-C chemokine receptor activity(GO:0016494)
0.0 0.2 GO:0017150 tRNA dihydrouridine synthase activity(GO:0017150)
0.0 0.2 GO:0042500 aspartic endopeptidase activity, intramembrane cleaving(GO:0042500)
0.0 0.3 GO:0035198 miRNA binding(GO:0035198)
0.0 0.1 GO:0004422 hypoxanthine phosphoribosyltransferase activity(GO:0004422)
0.0 1.1 GO:0005109 frizzled binding(GO:0005109)
0.0 0.4 GO:0030544 Hsp70 protein binding(GO:0030544)
0.0 0.8 GO:0017069 snRNA binding(GO:0017069)
0.0 0.3 GO:0035925 AU-rich element binding(GO:0017091) mRNA 3'-UTR AU-rich region binding(GO:0035925)
0.0 0.5 GO:0031681 G-protein beta-subunit binding(GO:0031681)
0.0 0.7 GO:0030247 pattern binding(GO:0001871) polysaccharide binding(GO:0030247)
0.0 0.2 GO:0015616 DNA translocase activity(GO:0015616)
0.0 0.2 GO:0004731 purine-nucleoside phosphorylase activity(GO:0004731)
0.0 0.1 GO:0031769 glucagon receptor binding(GO:0031769)
0.0 0.5 GO:0003785 actin monomer binding(GO:0003785)
0.0 0.1 GO:0016361 activin receptor activity, type I(GO:0016361)
0.0 0.4 GO:0008449 N-acetylglucosamine-6-sulfatase activity(GO:0008449)
0.0 0.1 GO:0033829 O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase activity(GO:0033829)
0.0 0.2 GO:0016454 serine C-palmitoyltransferase activity(GO:0004758) C-palmitoyltransferase activity(GO:0016454)
0.0 0.4 GO:0070411 I-SMAD binding(GO:0070411)
0.0 0.2 GO:0001102 RNA polymerase II activating transcription factor binding(GO:0001102)
0.0 0.2 GO:0030628 pre-mRNA 3'-splice site binding(GO:0030628)
0.0 0.3 GO:0004703 G-protein coupled receptor kinase activity(GO:0004703)
0.0 0.1 GO:0004662 CAAX-protein geranylgeranyltransferase activity(GO:0004662)
0.0 0.3 GO:0005123 death receptor binding(GO:0005123)
0.0 0.3 GO:0061608 nuclear import signal receptor activity(GO:0061608)
0.0 0.1 GO:0047493 sphingomyelin synthase activity(GO:0033188) ceramide cholinephosphotransferase activity(GO:0047493)
0.0 0.1 GO:0008597 calcium-dependent protein serine/threonine phosphatase regulator activity(GO:0008597)
0.0 0.1 GO:0004332 fructose-bisphosphate aldolase activity(GO:0004332)
0.0 0.2 GO:0008494 translation activator activity(GO:0008494)
0.0 0.4 GO:1990841 promoter-specific chromatin binding(GO:1990841)
0.0 0.1 GO:0008970 phosphatidylcholine 1-acylhydrolase activity(GO:0008970)
0.0 1.5 GO:0001594 trace-amine receptor activity(GO:0001594)
0.0 0.1 GO:0072518 Rho-dependent protein serine/threonine kinase activity(GO:0072518)
0.0 0.3 GO:0016273 arginine N-methyltransferase activity(GO:0016273) protein-arginine N-methyltransferase activity(GO:0016274)
0.0 0.2 GO:0032977 membrane insertase activity(GO:0032977)
0.0 0.1 GO:0008515 sugar:proton symporter activity(GO:0005351) cation:sugar symporter activity(GO:0005402) sucrose:proton symporter activity(GO:0008506) sucrose transmembrane transporter activity(GO:0008515) disaccharide transmembrane transporter activity(GO:0015154) oligosaccharide transmembrane transporter activity(GO:0015157)
0.0 0.2 GO:0030368 interleukin-17 receptor activity(GO:0030368)
0.0 0.6 GO:0042923 neuropeptide binding(GO:0042923)
0.0 0.2 GO:0005391 sodium:potassium-exchanging ATPase activity(GO:0005391)
0.0 0.1 GO:0034597 phosphatidylinositol-4,5-bisphosphate 4-phosphatase activity(GO:0034597)
0.0 0.3 GO:0004382 guanosine-diphosphatase activity(GO:0004382) uridine-diphosphatase activity(GO:0045134)
0.0 0.3 GO:0019210 protein kinase inhibitor activity(GO:0004860) kinase inhibitor activity(GO:0019210)
0.0 0.2 GO:0008301 DNA binding, bending(GO:0008301)
0.0 0.1 GO:0008349 MAP kinase kinase kinase kinase activity(GO:0008349)
0.0 0.3 GO:0003887 DNA-directed DNA polymerase activity(GO:0003887)
0.0 0.3 GO:0005338 nucleotide-sugar transmembrane transporter activity(GO:0005338)
0.0 0.1 GO:0000064 L-ornithine transmembrane transporter activity(GO:0000064)
0.0 0.4 GO:0001103 RNA polymerase II repressing transcription factor binding(GO:0001103)
0.0 0.4 GO:0030165 PDZ domain binding(GO:0030165)
0.0 0.4 GO:0045182 translation regulator activity(GO:0045182)
0.0 1.0 GO:0003724 RNA helicase activity(GO:0003724)
0.0 0.2 GO:0034237 protein kinase A regulatory subunit binding(GO:0034237)
0.0 0.1 GO:0044323 retinoic acid-responsive element binding(GO:0044323)
0.0 0.3 GO:0000993 RNA polymerase II core binding(GO:0000993)
0.0 0.1 GO:0005549 odorant binding(GO:0005549)
0.0 0.1 GO:0005324 long-chain fatty acid transporter activity(GO:0005324)
0.0 0.1 GO:0016907 G-protein coupled acetylcholine receptor activity(GO:0016907)
0.0 0.5 GO:0016538 cyclin-dependent protein serine/threonine kinase regulator activity(GO:0016538)
0.0 0.0 GO:0047961 glycine N-acyltransferase activity(GO:0047961)
0.0 0.0 GO:0042806 fucose binding(GO:0042806)
0.0 0.3 GO:0042800 histone methyltransferase activity (H3-K4 specific)(GO:0042800)
0.0 0.2 GO:0017136 histone deacetylase activity(GO:0004407) NAD-dependent histone deacetylase activity(GO:0017136)
0.0 0.1 GO:0060182 apelin receptor activity(GO:0060182)
0.0 0.2 GO:0008409 5'-3' exonuclease activity(GO:0008409)
0.0 0.1 GO:0008191 metalloendopeptidase inhibitor activity(GO:0008191)
0.0 0.2 GO:0015279 store-operated calcium channel activity(GO:0015279)
0.0 0.0 GO:0001596 angiotensin type I receptor activity(GO:0001596)
0.0 0.0 GO:0072571 ADP-D-ribose binding(GO:0072570) mono-ADP-D-ribose binding(GO:0072571)
0.0 0.1 GO:0005522 profilin binding(GO:0005522)
0.0 0.1 GO:0070840 dynein complex binding(GO:0070840)
0.0 0.2 GO:0004143 diacylglycerol kinase activity(GO:0004143)
0.0 0.1 GO:0015386 monovalent cation:proton antiporter activity(GO:0005451) sodium:proton antiporter activity(GO:0015385) potassium:proton antiporter activity(GO:0015386)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.6 PID CIRCADIAN PATHWAY Circadian rhythm pathway
0.0 0.4 PID INTEGRIN4 PATHWAY Alpha6 beta4 integrin-ligand interactions
0.0 0.7 PID IL23 PATHWAY IL23-mediated signaling events
0.0 0.2 PID ANTHRAX PATHWAY Cellular roles of Anthrax toxin
0.0 0.4 PID ALK2 PATHWAY ALK2 signaling events
0.0 1.0 PID HES HEY PATHWAY Notch-mediated HES/HEY network
0.0 0.6 PID FRA PATHWAY Validated transcriptional targets of AP1 family members Fra1 and Fra2
0.0 1.9 WNT SIGNALING Genes related to Wnt-mediated signal transduction
0.0 0.6 PID HEDGEHOG GLI PATHWAY Hedgehog signaling events mediated by Gli proteins
0.0 0.5 PID FOXM1 PATHWAY FOXM1 transcription factor network
0.0 0.3 PID BARD1 PATHWAY BARD1 signaling events
0.0 0.4 PID ALPHA SYNUCLEIN PATHWAY Alpha-synuclein signaling
0.0 0.7 PID RAC1 PATHWAY RAC1 signaling pathway
0.0 0.4 PID WNT NONCANONICAL PATHWAY Noncanonical Wnt signaling pathway
0.0 0.2 PID ATR PATHWAY ATR signaling pathway
0.0 0.2 PID TAP63 PATHWAY Validated transcriptional targets of TAp63 isoforms
0.0 0.1 PID TRAIL PATHWAY TRAIL signaling pathway
0.0 0.7 PID FANCONI PATHWAY Fanconi anemia pathway
0.0 0.2 PID PRL SIGNALING EVENTS PATHWAY Signaling events mediated by PRL
0.0 0.8 PID MYC ACTIV PATHWAY Validated targets of C-MYC transcriptional activation
0.0 0.1 PID IGF1 PATHWAY IGF1 pathway
0.0 0.2 PID DNA PK PATHWAY DNA-PK pathway in nonhomologous end joining
0.0 0.4 ST JNK MAPK PATHWAY JNK MAPK Pathway
0.0 0.5 PID REG GR PATHWAY Glucocorticoid receptor regulatory network
0.0 0.3 PID HDAC CLASSII PATHWAY Signaling events mediated by HDAC Class II
0.0 0.0 ST INTERFERON GAMMA PATHWAY Interferon gamma pathway.

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.8 REACTOME ORGANIC CATION ANION ZWITTERION TRANSPORT Genes involved in Organic cation/anion/zwitterion transport
0.1 0.8 REACTOME SYNTHESIS OF PE Genes involved in Synthesis of PE
0.1 0.6 REACTOME SLBP DEPENDENT PROCESSING OF REPLICATION DEPENDENT HISTONE PRE MRNAS Genes involved in SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs
0.1 0.6 REACTOME REGULATION OF AMPK ACTIVITY VIA LKB1 Genes involved in Regulation of AMPK activity via LKB1
0.1 0.6 REACTOME NEF MEDIATED DOWNREGULATION OF MHC CLASS I COMPLEX CELL SURFACE EXPRESSION Genes involved in Nef mediated downregulation of MHC class I complex cell surface expression
0.1 0.5 REACTOME CHYLOMICRON MEDIATED LIPID TRANSPORT Genes involved in Chylomicron-mediated lipid transport
0.0 0.9 REACTOME FANCONI ANEMIA PATHWAY Genes involved in Fanconi Anemia pathway
0.0 0.5 REACTOME REGULATION OF PYRUVATE DEHYDROGENASE PDH COMPLEX Genes involved in Regulation of pyruvate dehydrogenase (PDH) complex
0.0 0.4 REACTOME EARLY PHASE OF HIV LIFE CYCLE Genes involved in Early Phase of HIV Life Cycle
0.0 0.5 REACTOME INHIBITION OF REPLICATION INITIATION OF DAMAGED DNA BY RB1 E2F1 Genes involved in Inhibition of replication initiation of damaged DNA by RB1/E2F1
0.0 0.2 REACTOME RAF MAP KINASE CASCADE Genes involved in RAF/MAP kinase cascade
0.0 0.4 REACTOME SIGNALING BY BMP Genes involved in Signaling by BMP
0.0 0.3 REACTOME GLUTATHIONE CONJUGATION Genes involved in Glutathione conjugation
0.0 0.4 REACTOME LATENT INFECTION OF HOMO SAPIENS WITH MYCOBACTERIUM TUBERCULOSIS Genes involved in Latent infection of Homo sapiens with Mycobacterium tuberculosis
0.0 0.3 REACTOME SYNTHESIS SECRETION AND INACTIVATION OF GIP Genes involved in Synthesis, Secretion, and Inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP)
0.0 0.1 REACTOME TETRAHYDROBIOPTERIN BH4 SYNTHESIS RECYCLING SALVAGE AND REGULATION Genes involved in Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation
0.0 0.1 REACTOME REGULATION OF IFNG SIGNALING Genes involved in Regulation of IFNG signaling
0.0 0.7 REACTOME GLYCOSPHINGOLIPID METABOLISM Genes involved in Glycosphingolipid metabolism
0.0 0.5 REACTOME ABC FAMILY PROTEINS MEDIATED TRANSPORT Genes involved in ABC-family proteins mediated transport
0.0 0.2 REACTOME UNWINDING OF DNA Genes involved in Unwinding of DNA
0.0 0.2 REACTOME CYCLIN A B1 ASSOCIATED EVENTS DURING G2 M TRANSITION Genes involved in Cyclin A/B1 associated events during G2/M transition
0.0 0.4 REACTOME APC CDC20 MEDIATED DEGRADATION OF NEK2A Genes involved in APC-Cdc20 mediated degradation of Nek2A
0.0 0.1 REACTOME PRESYNAPTIC NICOTINIC ACETYLCHOLINE RECEPTORS Genes involved in Presynaptic nicotinic acetylcholine receptors
0.0 0.3 REACTOME SYNTHESIS AND INTERCONVERSION OF NUCLEOTIDE DI AND TRIPHOSPHATES Genes involved in Synthesis and interconversion of nucleotide di- and triphosphates
0.0 0.3 REACTOME SRP DEPENDENT COTRANSLATIONAL PROTEIN TARGETING TO MEMBRANE Genes involved in SRP-dependent cotranslational protein targeting to membrane
0.0 0.3 REACTOME REGULATION OF GENE EXPRESSION IN BETA CELLS Genes involved in Regulation of gene expression in beta cells
0.0 0.3 REACTOME METAL ION SLC TRANSPORTERS Genes involved in Metal ion SLC transporters
0.0 0.4 REACTOME EXTENSION OF TELOMERES Genes involved in Extension of Telomeres
0.0 0.1 REACTOME G2 M DNA DAMAGE CHECKPOINT Genes involved in G2/M DNA damage checkpoint
0.0 0.4 REACTOME MRNA SPLICING MINOR PATHWAY Genes involved in mRNA Splicing - Minor Pathway
0.0 0.3 REACTOME PROCESSING OF CAPPED INTRONLESS PRE MRNA Genes involved in Processing of Capped Intronless Pre-mRNA
0.0 0.1 REACTOME HS GAG DEGRADATION Genes involved in HS-GAG degradation
0.0 0.2 REACTOME GLOBAL GENOMIC NER GG NER Genes involved in Global Genomic NER (GG-NER)
0.0 0.3 REACTOME SYNTHESIS OF PA Genes involved in Synthesis of PA
0.0 0.5 REACTOME REGULATION OF ORNITHINE DECARBOXYLASE ODC Genes involved in Regulation of ornithine decarboxylase (ODC)
0.0 0.1 REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.0 0.2 REACTOME A TETRASACCHARIDE LINKER SEQUENCE IS REQUIRED FOR GAG SYNTHESIS Genes involved in A tetrasaccharide linker sequence is required for GAG synthesis
0.0 0.2 REACTOME RNA POL II TRANSCRIPTION PRE INITIATION AND PROMOTER OPENING Genes involved in RNA Polymerase II Transcription Pre-Initiation And Promoter Opening
0.0 0.2 REACTOME NEPHRIN INTERACTIONS Genes involved in Nephrin interactions
0.0 0.1 REACTOME RNA POL II PRE TRANSCRIPTION EVENTS Genes involved in RNA Polymerase II Pre-transcription Events
0.0 0.1 REACTOME SIGNALING BY NODAL Genes involved in Signaling by NODAL