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PRJNA195909:zebrafish embryo and larva development
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Results for rcor1+rcor2+rcor3
Z-value: 0.41
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Transcription factors associated with rcor1+rcor2+rcor3
Activity-expression correlation:
| Gene | Promoter | Pearson corr. coef. | P-value | Plot |
|---|---|---|---|---|
| rcor2 | dr11_v1_chr7_-_24994722_24994722 | 0.33 | 3.9e-01 | Click! |
| rcor1 | dr11_v1_chr17_-_29271359_29271359 | 0.25 | 5.1e-01 | Click! |
| rcor3 | dr11_v1_chr22_+_38276024_38276024 | 0.13 | 7.4e-01 | Click! |
| Promoter | Log-likelihood | Transcript | Gene | Gene Info |
|---|---|---|---|---|
| chr10_+_8629275 Show fit | 0.44 |
ENSDART00000129643
|
apelin receptor b |
|
| chr9_-_30371247 Show fit | 0.42 |
ENSDART00000079068
|
ankyrin repeat and SOCS box containing 11 |
|
| chr17_-_8312923 Show fit | 0.39 |
ENSDART00000064678
|
lefty2 |
|
| chr2_-_56095275 Show fit | 0.29 |
ENSDART00000154701
|
si:ch211-178n15.1 |
|
| chr19_+_14059349 Show fit | 0.26 |
ENSDART00000166230
|
trophoblast glycoprotein a |
|
| chr10_+_19596214 Show fit | 0.25 |
ENSDART00000183110
|
|
|
| chr13_-_12021566 Show fit | 0.25 |
ENSDART00000125430
|
peroxisome proliferator-activated receptor gamma, coactivator-related 1 |
|
| chr7_+_5955160 Show fit | 0.25 |
ENSDART00000111053
|
zgc:171759 |
|
| chr17_+_26783828 Show fit | 0.24 |
ENSDART00000154921
|
La ribonucleoprotein domain family, member 1B |
|
| chr14_+_15484544 Show fit | 0.22 |
ENSDART00000188649
|
|
Network of associatons between targets according to the STRING database.
First level regulatory network of rcor1+rcor2+rcor3
Gene Ontology Analysis
Gene overrepresentation in biological process category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 0.5 | GO:0060046 | binding of sperm to zona pellucida(GO:0007339) egg coat formation(GO:0035803) regulation of acrosome reaction(GO:0060046) positive regulation of acrosome reaction(GO:2000344) |
| 0.1 | 0.4 | GO:1903587 | regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis(GO:1903587) positive regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis(GO:1903589) |
| 0.1 | 0.4 | GO:0007221 | positive regulation of transcription of Notch receptor target(GO:0007221) |
| 0.0 | 0.4 | GO:0003128 | heart field specification(GO:0003128) |
| 0.1 | 0.3 | GO:0060829 | negative regulation of canonical Wnt signaling pathway involved in neural plate anterior/posterior pattern formation(GO:0060829) |
| 0.1 | 0.2 | GO:0001120 | DNA-templated transcriptional open complex formation(GO:0001112) transcriptional open complex formation at RNA polymerase II promoter(GO:0001113) protein-DNA complex remodeling(GO:0001120) |
| 0.1 | 0.2 | GO:0060945 | activation of transmembrane receptor protein tyrosine kinase activity(GO:0007171) Schwann cell migration(GO:0036135) cardiac neuron differentiation(GO:0060945) cardiac neuron development(GO:0060959) |
| 0.1 | 0.2 | GO:0097384 | ether lipid biosynthetic process(GO:0008611) glycerol ether biosynthetic process(GO:0046504) cellular lipid biosynthetic process(GO:0097384) ether biosynthetic process(GO:1901503) |
| 0.0 | 0.2 | GO:0097341 | inhibition of cysteine-type endopeptidase activity(GO:0097340) zymogen inhibition(GO:0097341) |
| 0.0 | 0.2 | GO:0045743 | positive regulation of fibroblast growth factor receptor signaling pathway(GO:0045743) |
Gene overrepresentation in cellular component category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 0.2 | GO:0033553 | rDNA heterochromatin(GO:0033553) |
| 0.0 | 0.2 | GO:0005673 | transcription factor TFIIE complex(GO:0005673) |
| 0.0 | 0.1 | GO:0005797 | Golgi medial cisterna(GO:0005797) |
| 0.0 | 0.1 | GO:0005952 | cAMP-dependent protein kinase complex(GO:0005952) |
| 0.0 | 0.1 | GO:0097550 | transcriptional preinitiation complex(GO:0097550) |
| 0.0 | 0.1 | GO:0071006 | U2-type catalytic step 1 spliceosome(GO:0071006) catalytic step 1 spliceosome(GO:0071012) |
| 0.0 | 0.1 | GO:0016586 | RSC complex(GO:0016586) |
| 0.0 | 0.1 | GO:0016012 | sarcoglycan complex(GO:0016012) |
| 0.0 | 0.1 | GO:0035060 | brahma complex(GO:0035060) |
Gene overrepresentation in molecular function category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.1 | 0.4 | GO:0060182 | apelin receptor activity(GO:0060182) |
| 0.0 | 0.4 | GO:0005160 | transforming growth factor beta receptor binding(GO:0005160) |
| 0.0 | 0.3 | GO:0035804 | structural constituent of egg coat(GO:0035804) |
| 0.0 | 0.2 | GO:0070698 | type I activin receptor binding(GO:0070698) |
| 0.0 | 0.2 | GO:0010859 | calcium-dependent cysteine-type endopeptidase inhibitor activity(GO:0010859) |
| 0.0 | 0.2 | GO:0030296 | protein tyrosine kinase activator activity(GO:0030296) |
| 0.0 | 0.1 | GO:0071885 | N-terminal protein N-methyltransferase activity(GO:0071885) |
| 0.0 | 0.1 | GO:0030882 | lipid antigen binding(GO:0030882) |
| 0.0 | 0.1 | GO:0004813 | alanine-tRNA ligase activity(GO:0004813) |
| 0.0 | 0.1 | GO:0072591 | N-acetyl-L-aspartate-L-glutamate ligase activity(GO:0072590) citrate-L-glutamate ligase activity(GO:0072591) |
Gene overrepresentation in curated gene sets: canonical pathways category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 0.1 | PID ERBB NETWORK PATHWAY | ErbB receptor signaling network |
Gene overrepresentation in curated gene sets: REACTOME pathways category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 0.1 | REACTOME DOWNREGULATION OF ERBB2 ERBB3 SIGNALING | Genes involved in Downregulation of ERBB2:ERBB3 signaling |
| 0.0 | 0.1 | REACTOME SYNTHESIS OF VERY LONG CHAIN FATTY ACYL COAS | Genes involved in Synthesis of very long-chain fatty acyl-CoAs |