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PRJNA195909:zebrafish embryo and larva development
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Results for rargb_pparab
Z-value: 1.73
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Transcription factors associated with rargb_pparab
Activity-expression correlation:
| Gene | Promoter | Pearson corr. coef. | P-value | Plot |
|---|---|---|---|---|
| rargb | dr11_v1_chr11_+_2089461_2089461 | 0.52 | 1.5e-01 | Click! |
| pparab | dr11_v1_chr25_+_2198781_2198781 | -0.37 | 3.3e-01 | Click! |
| Promoter | Log-likelihood | Transcript | Gene | Gene Info |
|---|---|---|---|---|
| chr10_-_44027391 Show fit | 3.93 |
ENSDART00000145404
|
crystallin, beta B1 |
|
| chr2_-_5728843 Show fit | 3.60 |
ENSDART00000014020
|
somatostatin 2 |
|
| chr11_+_30729745 Show fit | 3.28 |
ENSDART00000103270
|
solute carrier family 22 (organic anion transporter), member 7a |
|
| chr10_+_9561066 Show fit | 2.88 |
ENSDART00000136281
|
si:ch211-243g18.2 |
|
| chr10_-_29900546 Show fit | 2.81 |
ENSDART00000147441
|
lens intrinsic membrane protein 2.1 |
|
| chr2_+_42191592 Show fit | 2.69 |
ENSDART00000144716
|
caveolae associated protein 4a |
|
| chr3_-_46811611 Show fit | 2.54 |
ENSDART00000134092
|
ELAV like neuron-specific RNA binding protein 3 |
|
| chr13_-_39159810 Show fit | 2.48 |
ENSDART00000131508
|
collagen, type IX, alpha 1b |
|
| chr12_-_5120339 Show fit | 2.37 |
ENSDART00000168759
|
retinol binding protein 4, plasma |
|
| chr3_-_18575868 Show fit | 2.36 |
ENSDART00000122968
|
aquaporin 8b |
Network of associatons between targets according to the STRING database.
First level regulatory network of rargb_pparab
Gene Ontology Analysis
Gene overrepresentation in biological process category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.1 | 6.9 | GO:0002088 | lens development in camera-type eye(GO:0002088) |
| 0.7 | 4.6 | GO:0034633 | retinol transport(GO:0034633) isoprenoid transport(GO:0046864) terpenoid transport(GO:0046865) |
| 0.0 | 4.1 | GO:0050767 | regulation of neurogenesis(GO:0050767) |
| 0.0 | 4.0 | GO:0098656 | anion transmembrane transport(GO:0098656) |
| 0.1 | 3.5 | GO:0055003 | cardiac myofibril assembly(GO:0055003) |
| 0.1 | 3.5 | GO:0030032 | lamellipodium assembly(GO:0030032) |
| 0.0 | 3.5 | GO:0006936 | muscle contraction(GO:0006936) |
| 0.3 | 3.1 | GO:0036368 | cone photoresponse recovery(GO:0036368) |
| 0.1 | 3.1 | GO:0015985 | energy coupled proton transport, down electrochemical gradient(GO:0015985) ATP synthesis coupled proton transport(GO:0015986) |
| 0.1 | 3.0 | GO:0030388 | fructose 1,6-bisphosphate metabolic process(GO:0030388) |
Gene overrepresentation in cellular component category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 33.7 | GO:0005576 | extracellular region(GO:0005576) |
| 0.1 | 9.1 | GO:0005882 | intermediate filament(GO:0005882) |
| 0.0 | 9.0 | GO:0031012 | extracellular matrix(GO:0031012) |
| 0.1 | 8.2 | GO:0005746 | mitochondrial respiratory chain(GO:0005746) |
| 0.1 | 8.2 | GO:0005581 | collagen trimer(GO:0005581) |
| 0.1 | 4.5 | GO:0005865 | striated muscle thin filament(GO:0005865) myofilament(GO:0036379) |
| 0.1 | 4.4 | GO:0001725 | stress fiber(GO:0001725) contractile actin filament bundle(GO:0097517) |
| 0.0 | 3.6 | GO:0005884 | actin filament(GO:0005884) |
| 0.1 | 2.8 | GO:0044853 | caveola(GO:0005901) plasma membrane raft(GO:0044853) |
| 0.0 | 2.8 | GO:0030018 | Z disc(GO:0030018) |
Gene overrepresentation in molecular function category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 12.1 | GO:0051015 | actin filament binding(GO:0051015) |
| 0.1 | 11.6 | GO:0005212 | structural constituent of eye lens(GO:0005212) |
| 0.0 | 9.0 | GO:0005198 | structural molecule activity(GO:0005198) |
| 0.0 | 8.3 | GO:0005509 | calcium ion binding(GO:0005509) |
| 0.0 | 5.8 | GO:0005201 | extracellular matrix structural constituent(GO:0005201) |
| 0.0 | 5.7 | GO:0005179 | hormone activity(GO:0005179) |
| 0.7 | 4.6 | GO:0034632 | retinol transporter activity(GO:0034632) |
| 0.1 | 4.4 | GO:0005178 | integrin binding(GO:0005178) |
| 0.4 | 3.8 | GO:0015250 | water channel activity(GO:0015250) |
| 0.1 | 3.7 | GO:0008201 | heparin binding(GO:0008201) |
Gene overrepresentation in curated gene sets: canonical pathways category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 7.6 | NABA ECM GLYCOPROTEINS | Genes encoding structural ECM glycoproteins |
| 0.1 | 3.9 | NABA COLLAGENS | Genes encoding collagen proteins |
| 0.0 | 3.4 | NABA SECRETED FACTORS | Genes encoding secreted soluble factors |
| 0.0 | 2.4 | NABA ECM AFFILIATED | Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins |
| 0.1 | 1.8 | SIG REGULATION OF THE ACTIN CYTOSKELETON BY RHO GTPASES | Genes related to regulation of the actin cytoskeleton |
| 0.0 | 0.9 | PID RHODOPSIN PATHWAY | Visual signal transduction: Rods |
| 0.0 | 0.9 | NABA PROTEOGLYCANS | Genes encoding proteoglycans |
| 0.0 | 0.9 | ST GA13 PATHWAY | G alpha 13 Pathway |
| 0.0 | 0.9 | PID HNF3B PATHWAY | FOXA2 and FOXA3 transcription factor networks |
| 0.0 | 0.9 | PID REG GR PATHWAY | Glucocorticoid receptor regulatory network |
Gene overrepresentation in curated gene sets: REACTOME pathways category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.2 | 9.8 | REACTOME RESPIRATORY ELECTRON TRANSPORT | Genes involved in Respiratory electron transport |
| 0.1 | 3.9 | REACTOME COLLAGEN FORMATION | Genes involved in Collagen formation |
| 0.2 | 3.2 | REACTOME ACTIVATION OF RAC | Genes involved in Activation of Rac |
| 0.1 | 2.8 | REACTOME STRIATED MUSCLE CONTRACTION | Genes involved in Striated Muscle Contraction |
| 0.1 | 2.6 | REACTOME PROSTACYCLIN SIGNALLING THROUGH PROSTACYCLIN RECEPTOR | Genes involved in Prostacyclin signalling through prostacyclin receptor |
| 0.5 | 2.1 | REACTOME REGULATION OF COMPLEMENT CASCADE | Genes involved in Regulation of Complement cascade |
| 0.0 | 1.4 | REACTOME ASPARAGINE N LINKED GLYCOSYLATION | Genes involved in Asparagine N-linked glycosylation |
| 0.1 | 1.2 | REACTOME INSULIN RECEPTOR RECYCLING | Genes involved in Insulin receptor recycling |
| 0.1 | 0.9 | REACTOME BILE SALT AND ORGANIC ANION SLC TRANSPORTERS | Genes involved in Bile salt and organic anion SLC transporters |
| 0.1 | 0.9 | REACTOME BRANCHED CHAIN AMINO ACID CATABOLISM | Genes involved in Branched-chain amino acid catabolism |