ISMARA results: prox1a+prox2+prox3

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PRJNA195909:zebrafish embryo and larva development

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Results for prox1a+prox2+prox3

Z-value: 0.64

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Transcription factors associated with prox1a+prox2+prox3

Gene Symbol	Gene ID	Gene Info
prox2 NCBI UniProt	ENSDARG00000041952	prospero homeobox 2
prox1a NCBI UniProt	ENSDARG00000055158	prospero homeobox 1a
prox3 NCBI UniProt	ENSDARG00000088810	prospero homeobox 3
prox3 NCBI UniProt	ENSDARG00000113014	prospero homeobox 3
prox2 NCBI UniProt	ENSDARG00000117137	prospero homeobox 2

Activity-expression correlation:

Gene	Promoter	Pearson corr. coef.	P-value	Plot
prox2	dr11_v1_chr17_-_52521002_52521002	0.36	3.5e-01	Click!
prox1b	dr11_v1_chr7_-_19940473_19940473	0.30	4.3e-01	Click!
prox1a	dr11_v1_chr17_-_32865788_32865788	0.24	5.4e-01	Click!

Activity profile of prox1a+prox2+prox3 motif

Sorted Z-values of prox1a+prox2+prox3 motif

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Promoter	Log-likelihood	Transcript	Gene	Gene Info
chr7_+_29952169 Show fit	1.02	ENSDART00000173540 ENSDART00000173940 ENSDART00000173906 ENSDART00000173772 ENSDART00000173506 ENSDART00000039657	tpma NCBI UniProt Show fit	alpha-tropomyosin
chr7_+_29951997 Show fit	0.82	ENSDART00000173453	tpma NCBI UniProt Show fit	alpha-tropomyosin
chr10_-_31782616 Show fit	0.63	ENSDART00000128839	fez1 NCBI UniProt Show fit	fasciculation and elongation protein zeta 1 (zygin I)
chr9_-_23033818 Show fit	0.62	ENSDART00000022392	rnd3b NCBI UniProt Show fit	Rho family GTPase 3b
chr2_+_2470687 Show fit	0.61	ENSDART00000184024 ENSDART00000061955	myl13 NCBI UniProt Show fit	myosin, light chain 13
chr1_+_44442140 Show fit	0.52	ENSDART00000190592	crybb1l2 NCBI UniProt Show fit	crystallin, beta B1, like 2
chr15_+_32711663 Show fit	0.45	ENSDART00000157854 ENSDART00000167515	postnb NCBI UniProt Show fit	periostin, osteoblast specific factor b
chr2_+_25658112 Show fit	0.42	ENSDART00000051234	tnika NCBI UniProt Show fit	TRAF2 and NCK interacting kinase a
chr19_+_42886413 Show fit	0.39	ENSDART00000151298	arpp21 NCBI UniProt Show fit	cAMP-regulated phosphoprotein, 21
chr9_-_42696408 Show fit	0.38	ENSDART00000144744	col5a2a NCBI UniProt Show fit	collagen, type V, alpha 2a

Showing 1 to 10 of 97 entries

Network of associatons between targets according to the STRING database.

First level regulatory network of prox1a+prox2+prox3

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

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Log-likelihood per target	Total log-likelihood	Term	Description
0.0	1.9	GO:0061515	myeloid cell development(GO:0061515)
0.0	0.5	GO:0016203	muscle attachment(GO:0016203)
0.1	0.4	GO:0071939	vitamin A transport(GO:0071938) vitamin A import(GO:0071939)
0.1	0.3	GO:1902455	negative regulation of stem cell population maintenance(GO:1902455)
0.0	0.3	GO:0032438	melanosome organization(GO:0032438)
0.0	0.3	GO:0034315	regulation of Arp2/3 complex-mediated actin nucleation(GO:0034315)
0.1	0.2	GO:0000711	meiotic DNA repair synthesis(GO:0000711)
0.0	0.2	GO:1901098	positive regulation of autophagosome maturation(GO:1901098)
0.0	0.2	GO:0048280	vesicle fusion with Golgi apparatus(GO:0048280)

Showing 1 to 9 of 9 entries

Gene overrepresentation in cellular component category:

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Log-likelihood per target	Total log-likelihood	Term	Description
0.0	1.9	GO:0005884	actin filament(GO:0005884)
0.1	0.4	GO:0005588	collagen type V trimer(GO:0005588)
0.0	0.3	GO:0005868	cytoplasmic dynein complex(GO:0005868)
0.0	0.3	GO:0032588	trans-Golgi network membrane(GO:0032588)
0.1	0.2	GO:0031466	Cul5-RING ubiquitin ligase complex(GO:0031466)

Showing 1 to 5 of 5 entries

Gene overrepresentation in molecular function category:

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Log-likelihood per target	Total log-likelihood	Term	Description
0.0	1.7	GO:0042803	protein homodimerization activity(GO:0042803)
0.1	0.4	GO:0034632	retinol transporter activity(GO:0034632)
0.0	0.3	GO:0045503	dynein light chain binding(GO:0045503)
0.0	0.3	GO:0004720	protein-lysine 6-oxidase activity(GO:0004720)
0.0	0.1	GO:0019777	Atg12 transferase activity(GO:0019777)
0.0	0.1	GO:0004345	glucose-6-phosphate dehydrogenase activity(GO:0004345)
0.0	0.1	GO:0019107	myristoyltransferase activity(GO:0019107)
0.0	0.1	GO:0019136	deoxynucleoside kinase activity(GO:0019136)
0.0	0.1	GO:0004745	retinol dehydrogenase activity(GO:0004745)
0.0	0.1	GO:0004396	glucokinase activity(GO:0004340) hexokinase activity(GO:0004396) glucose binding(GO:0005536) fructokinase activity(GO:0008865) mannokinase activity(GO:0019158)

Showing 1 to 10 of 11 entries

Results for prox1a+prox2+prox3

Z-value: 0.64

Motif logo

Transcription factors associated with prox1a+prox2+prox3

Activity-expression correlation:

Activity profile of prox1a+prox2+prox3 motif

Sorted Z-values of prox1a+prox2+prox3 motif

Top targets:

Network of associatons between targets according to the STRING database.

First level regulatory network of prox1a+prox2+prox3

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Gene overrepresentation in cellular component category:

Gene overrepresentation in molecular function category: