ISMARA results: pou5f3

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PRJNA195909:zebrafish embryo and larva development

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Results for pou5f3

Z-value: 0.52

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Transcription factors associated with pou5f3

Gene Symbol	Gene ID	Gene Info
pou5f3 NCBI UniProt	ENSDARG00000044774	POU domain, class 5, transcription factor 3

Activity-expression correlation:

Gene	Promoter	Pearson corr. coef.	P-value	Plot
pou5f3	dr11_v1_chr21_-_13690712_13690712	0.66	5.3e-02	Click!

Activity profile of pou5f3 motif

Sorted Z-values of pou5f3 motif

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Promoter	Log-likelihood	Transcript	Gene	Gene Info
chr8_+_41038141 Show fit	1.47	ENSDART00000075620	gpat2 NCBI UniProt Show fit	glycerol-3-phosphate acyltransferase 2, mitochondrial
chr8_+_41037541 Show fit	1.28	ENSDART00000129344	gpat2 NCBI UniProt Show fit	glycerol-3-phosphate acyltransferase 2, mitochondrial
chr1_-_55068941 Show fit	1.06	ENSDART00000152143 ENSDART00000152590	peli1a NCBI UniProt Show fit	pellino E3 ubiquitin protein ligase 1a
chr5_-_30074332 Show fit	1.06	ENSDART00000147963	bco2a NCBI UniProt Show fit	beta-carotene oxygenase 2a
chr7_+_33424044 Show fit	0.99	ENSDART00000180260	glceb NCBI UniProt Show fit	glucuronic acid epimerase b
chr10_-_44560165 Show fit	0.96	ENSDART00000181217 ENSDART00000076084	npm2b NCBI UniProt Show fit	nucleophosmin/nucleoplasmin, 2b
chr9_-_2945008 Show fit	0.88	ENSDART00000183452	zak NCBI UniProt Show fit	sterile alpha motif and leucine zipper containing kinase AZK
chr24_-_20641000 Show fit	0.83	ENSDART00000166135	zbtb47b NCBI UniProt Show fit	zinc finger and BTB domain containing 47b
chr8_-_44238526 Show fit	0.68	ENSDART00000061115 ENSDART00000132473 ENSDART00000138019 ENSDART00000133021	piwil1 NCBI UniProt Show fit	piwi-like RNA-mediated gene silencing 1
chr23_-_33709964 Show fit	0.59	ENSDART00000143333 ENSDART00000130338	pou6f1 NCBI UniProt Show fit	POU class 6 homeobox 1

Showing 1 to 10 of 30 entries

Network of associatons between targets according to the STRING database.

First level regulatory network of pou5f3

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

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Log-likelihood per target	Total log-likelihood	Term	Description
0.4	2.8	GO:1990511	piRNA biosynthetic process(GO:1990511)
0.2	1.1	GO:0008592	regulation of Toll signaling pathway(GO:0008592)
0.1	1.1	GO:0016121	carotene metabolic process(GO:0016119) carotene catabolic process(GO:0016121) terpene metabolic process(GO:0042214) terpene catabolic process(GO:0046247)
0.1	1.0	GO:0030202	heparin metabolic process(GO:0030202) heparin biosynthetic process(GO:0030210)
0.1	1.0	GO:0045740	positive regulation of DNA replication(GO:0045740)
0.1	0.7	GO:0035093	spermatid nucleus differentiation(GO:0007289) regulation of transposition(GO:0010528) negative regulation of transposition(GO:0010529) sperm chromatin condensation(GO:0035092) spermatogenesis, exchange of chromosomal proteins(GO:0035093)
0.0	0.5	GO:0051209	release of sequestered calcium ion into cytosol(GO:0051209)
0.0	0.5	GO:0048814	regulation of dendrite morphogenesis(GO:0048814)
0.0	0.5	GO:0046847	filopodium assembly(GO:0046847)
0.0	0.3	GO:2000463	postsynaptic density assembly(GO:0097107) modulation of excitatory postsynaptic potential(GO:0098815) positive regulation of excitatory postsynaptic potential(GO:2000463)

Showing 1 to 10 of 12 entries

Gene overrepresentation in cellular component category:

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Log-likelihood per target	Total log-likelihood	Term	Description
0.0	0.7	GO:0043186	P granule(GO:0043186)
0.1	0.5	GO:0032045	guanyl-nucleotide exchange factor complex(GO:0032045)
0.0	0.5	GO:0030667	secretory granule membrane(GO:0030667)

Showing 1 to 3 of 3 entries

Gene overrepresentation in molecular function category:

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Log-likelihood per target	Total log-likelihood	Term	Description
0.3	2.8	GO:0004366	glycerol-3-phosphate O-acyltransferase activity(GO:0004366)
0.1	1.1	GO:0003834	beta-carotene 15,15'-monooxygenase activity(GO:0003834) carotenoid dioxygenase activity(GO:0010436)
0.2	1.0	GO:0047464	heparosan-N-sulfate-glucuronate 5-epimerase activity(GO:0047464)
0.1	0.7	GO:0034584	piRNA binding(GO:0034584)
0.0	0.5	GO:0005220	inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity(GO:0005220)
0.1	0.3	GO:0004185	serine-type carboxypeptidase activity(GO:0004185)
0.0	0.3	GO:0030160	GKAP/Homer scaffold activity(GO:0030160)
0.0	0.3	GO:0008474	palmitoyl-(protein) hydrolase activity(GO:0008474) palmitoyl hydrolase activity(GO:0098599)
0.0	0.2	GO:0002061	uracil binding(GO:0002058) pyrimidine nucleobase binding(GO:0002061) dihydropyrimidine dehydrogenase (NADP+) activity(GO:0017113)
0.0	0.1	GO:0001642	group III metabotropic glutamate receptor activity(GO:0001642)

Showing 1 to 10 of 10 entries

Gene overrepresentation in curated gene sets: canonical pathways category:

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Log-likelihood per target	Total log-likelihood	Term	Description
0.1	0.9	PID P38 GAMMA DELTA PATHWAY	Signaling mediated by p38-gamma and p38-delta
0.0	0.5	PID CDC42 REG PATHWAY	Regulation of CDC42 activity

Showing 1 to 2 of 2 entries

Gene overrepresentation in curated gene sets: REACTOME pathways category:

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Log-likelihood per target	Total log-likelihood	Term	Description
0.1	2.8	REACTOME SYNTHESIS OF PA	Genes involved in Synthesis of PA
0.0	0.5	REACTOME NRAGE SIGNALS DEATH THROUGH JNK	Genes involved in NRAGE signals death through JNK
0.0	0.3	REACTOME ENOS ACTIVATION AND REGULATION	Genes involved in eNOS activation and regulation

Showing 1 to 3 of 3 entries

Results for pou5f3

Z-value: 0.52

Motif logo

Transcription factors associated with pou5f3

Activity-expression correlation:

Activity profile of pou5f3 motif

Sorted Z-values of pou5f3 motif

Top targets:

Network of associatons between targets according to the STRING database.

First level regulatory network of pou5f3

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Gene overrepresentation in cellular component category:

Gene overrepresentation in molecular function category:

Gene overrepresentation in curated gene sets: canonical pathways category:

Gene overrepresentation in curated gene sets: REACTOME pathways category: