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PRJNA195909:zebrafish embryo and larva development

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Results for pou4f2

Z-value: 0.43

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Transcription factors associated with pou4f2

Gene Symbol Gene ID Gene Info
ENSDARG00000069737 POU class 4 homeobox 2

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
pou4f2dr11_v1_chr1_+_36437585_364375850.166.7e-01Click!

Activity profile of pou4f2 motif

Sorted Z-values of pou4f2 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr2_+_36939749 0.43 ENSDART00000005382
growth arrest and DNA-damage-inducible, beta b
chr20_-_6532462 0.37 ENSDART00000054653
MCM3 minichromosome maintenance deficient 3 (S. cerevisiae), like
chr13_+_1089942 0.25 ENSDART00000054322
cannabinoid receptor interacting protein 1b
chr9_+_50001746 0.22 ENSDART00000058892
solute carrier family 38, member 11
chr9_-_8314028 0.18 ENSDART00000102739
si:ch211-145c1.1
chr5_-_26247973 0.17 ENSDART00000098527
endoplasmic reticulum aminopeptidase 1b
chr2_-_21082695 0.17 ENSDART00000032502
nebulette
chr19_-_18313303 0.17 ENSDART00000164644
ENSDART00000167480
ENSDART00000163104
si:dkey-208k4.2
chr10_+_5268054 0.16 ENSDART00000114491
receptor tyrosine kinase-like orphan receptor 2
chr17_+_26965351 0.15 ENSDART00000114215
ENSDART00000147192
grainyhead-like transcription factor 3
chr21_+_20396858 0.15 ENSDART00000003299
ENSDART00000146615
zgc:103482
chr12_-_35787801 0.14 ENSDART00000171682
apoptosis-associated tyrosine kinase b
chr22_+_10698549 0.14 ENSDART00000081228
abhydrolase domain containing 14A
chr19_-_31402429 0.14 ENSDART00000137292
transmembrane protein 106Bb
chr21_+_76739 0.14 ENSDART00000174654
arylsulfatase B
chr9_+_21793565 0.13 ENSDART00000134915
REV1, polymerase (DNA directed)
chr7_+_49862837 0.12 ENSDART00000174315
solute carrier family 1 (glial high affinity glutamate transporter), member 2a
chr14_-_7409364 0.12 ENSDART00000036463
DND microRNA-mediated repression inhibitor 1
chr17_-_29902187 0.11 ENSDART00000009104
estrogen-related receptor beta
chr13_-_14487524 0.11 ENSDART00000141103
GDNF family receptor alpha 4a
chr13_+_31180084 0.11 ENSDART00000133774
protein tyrosine phosphatase, non-receptor type 20
chr5_+_44064764 0.11 ENSDART00000143843
si:dkey-84j12.1
chr13_-_33194647 0.11 ENSDART00000134383
thyroid hormone receptor interactor 11
chr9_-_29003245 0.11 ENSDART00000183391
ENSDART00000188836
protein tyrosine phosphatase, non-receptor type 4a
chr20_+_41756996 0.10 ENSDART00000186393
family with sequence similarity 184, member A
chr17_+_51499789 0.10 ENSDART00000187701

chr2_+_23006792 0.10 ENSDART00000027782
MAP kinase interacting serine/threonine kinase 2a
chr14_-_31465905 0.10 ENSDART00000173108
glypican 3
chr1_-_22512063 0.10 ENSDART00000031546
ENSDART00000190987
cholinergic receptor, nicotinic, alpha 6
chr10_+_40284003 0.10 ENSDART00000062795
ENSDART00000193825
ENSDART00000113582
G protein-coupled receptor kinase interacting ArfGAP 2b
chr14_+_25817628 0.09 ENSDART00000047680
glycine receptor, alpha 1
chr9_-_43538328 0.09 ENSDART00000140526
zinc finger protein 385B
chr23_-_28141419 0.09 ENSDART00000133039
tachykinin 3a
chr24_+_19593197 0.09 ENSDART00000151923
solute carrier organic anion transporter family member 5A1a
chr9_-_3934963 0.09 ENSDART00000062336
ubiquitin protein ligase E3 component n-recognin 3
chr11_-_31226578 0.09 ENSDART00000109698
nucleus accumbens associated 1, BEN and BTB (POZ) domain containing b
chr16_+_25011994 0.09 ENSDART00000157312
zinc finger protein 1035
chr15_+_45994123 0.08 ENSDART00000124704
leucine rich repeat and fibronectin type III domain containing 1
chr11_+_44502410 0.08 ENSDART00000172998
endoplasmic reticulum oxidoreductase beta
chr2_+_29249561 0.08 ENSDART00000099157
cadherin 18, type 2a
chr3_-_30434016 0.08 ENSDART00000150958
leucine rich repeat containing 4Ba
chr20_+_38458084 0.08 ENSDART00000020153
ENSDART00000135912
coenzyme Q8A
chr14_-_7306983 0.08 ENSDART00000158914
si:ch211-51f19.1
chr3_-_30384353 0.08 ENSDART00000186832
leucine rich repeat containing 4Ba
chr8_-_40555340 0.08 ENSDART00000163348
NPC1 like intracellular cholesterol transporter 1
chr5_-_68782641 0.08 ENSDART00000141699
methylphosphate capping enzyme
chr15_-_5720583 0.07 ENSDART00000158034
ENSDART00000190332
ENSDART00000109599
URB1 ribosome biogenesis 1 homolog (S. cerevisiae)
chr2_+_12302527 0.07 ENSDART00000091298
ENSDART00000182569
Rho GTPase activating protein 21b
chr11_-_3860534 0.07 ENSDART00000082425
GATA binding protein 2a
chr16_+_40043673 0.07 ENSDART00000102552
ENSDART00000125484
tRNA methyltransferase 11 homolog (S. cerevisiae)
chr16_-_12173399 0.07 ENSDART00000142574
calsyntenin 3
chr2_-_30784198 0.07 ENSDART00000182523
ENSDART00000147355
regulator of G protein signaling 20
chr7_-_7764287 0.07 ENSDART00000173021
ENSDART00000113131
inturned planar cell polarity protein
chr20_-_31743553 0.07 ENSDART00000087405
SAM and SH3 domain containing 1a
chr7_-_69185124 0.07 ENSDART00000182217
ENSDART00000191359
ubiquitin specific peptidase 10
chr10_-_35103208 0.07 ENSDART00000192734
zgc:110006
chr12_+_32729470 0.07 ENSDART00000175712
RNA binding fox-1 homolog 3a
chr17_-_37395460 0.07 ENSDART00000148160
ENSDART00000075975
cysteine-rich protein 1
chr9_-_32158288 0.07 ENSDART00000037182
ankyrin repeat domain 44
chr19_+_42470396 0.07 ENSDART00000191679
si:dkey-166k12.1
chr20_+_13781779 0.07 ENSDART00000142999
ENSDART00000152471
lysophosphatidylglycerol acyltransferase 1
chr8_+_52314542 0.07 ENSDART00000013059
ENSDART00000125241
drebrin-like b
chr17_-_49438873 0.07 ENSDART00000004424
zinc finger protein 292a
chr7_+_53498152 0.07 ENSDART00000184497
zinc finger protein 609b
chr21_+_25226558 0.07 ENSDART00000168480
syncollin, tandem duplicate 2
chr4_+_9836465 0.07 ENSDART00000004879
heat shock protein 90, beta (grp94), member 1
chr9_-_50001606 0.06 ENSDART00000161648
ENSDART00000168514
sodium channel, voltage-gated, type I, alpha
chr5_+_37966505 0.06 ENSDART00000127648
platelet-activating factor acetylhydrolase 1b, catalytic subunit 2
chr18_-_2433011 0.06 ENSDART00000181922
ENSDART00000193276

chr11_+_3585934 0.06 ENSDART00000055694
cytidine deaminase b
chr17_+_8183393 0.06 ENSDART00000155957
tubby like protein 4b
chr8_-_4327473 0.06 ENSDART00000134378
cut-like homeobox 2b
chr11_-_3860199 0.06 ENSDART00000082420
GATA binding protein 2a
chr10_+_2582254 0.06 ENSDART00000016103
nucleoredoxin like 2
chr10_+_38775959 0.06 ENSDART00000192990
Down syndrome cell adhesion molecule a
chr4_-_2637689 0.06 ENSDART00000192550
ENSDART00000021953
ENSDART00000150344
component of oligomeric golgi complex 5
chr11_-_2478374 0.06 ENSDART00000173205
si:ch73-267c23.10
chr23_+_41912151 0.06 ENSDART00000191115
podocan
chr19_+_1688727 0.05 ENSDART00000115136
ENSDART00000166744
DENN/MADD domain containing 3a
chr10_+_38775408 0.05 ENSDART00000125045
Down syndrome cell adhesion molecule a
chr2_+_50608099 0.05 ENSDART00000185805
ENSDART00000111135
neuronal differentiation 6b
chr2_+_16696052 0.05 ENSDART00000022356
ENSDART00000164329
protein phosphatase 1, regulatory (inhibitor) subunit 7
chr16_+_25107344 0.05 ENSDART00000033211
zgc:66448
chr19_-_5103313 0.05 ENSDART00000037007
triosephosphate isomerase 1a
chr25_+_5972690 0.05 ENSDART00000067517
si:ch211-11i22.4
chr8_+_12951155 0.05 ENSDART00000081601
choline/ethanolamine phosphotransferase 1a
chr25_-_13842618 0.05 ENSDART00000160258
mitogen-activated protein kinase 8 interacting protein 1a
chr18_-_43993614 0.05 ENSDART00000148535
ENSDART00000077357
B cell CLL/lymphoma 9-like
chr5_+_51443009 0.05 ENSDART00000083350
Ras protein-specific guanine nucleotide-releasing factor 2b
chr20_+_18325556 0.04 ENSDART00000123559
zinc finger protein 521
chr14_+_28486213 0.04 ENSDART00000161852
stromal antigen 2b
chr17_+_6765621 0.04 ENSDART00000156637
ENSDART00000007622
AFG1 like ATPase a
chr25_+_28555584 0.04 ENSDART00000157046
si:ch211-190o6.3
chr6_-_46735380 0.04 ENSDART00000103455
TAR (HIV) RNA binding protein 2
chr20_-_24182689 0.04 ENSDART00000171184
mitogen-activated protein kinase kinase kinase 7
chr1_-_53756851 0.04 ENSDART00000122445
v-akt murine thymoma viral oncogene homolog 3b
chr17_+_11675362 0.04 ENSDART00000157911
kinesin family member 26Ba
chr24_+_24808955 0.04 ENSDART00000080963
DnaJ (Hsp40) homolog, subfamily C, member 5 beta
chr6_-_6248893 0.04 ENSDART00000124662
reticulon 4a
chr17_+_26352372 0.04 ENSDART00000155177
glutamate receptor, ionotropic, delta 1a
chr21_+_36623162 0.04 ENSDART00000027459
G protein-coupled receptor kinase 6
chr2_+_29249204 0.04 ENSDART00000168957
cadherin 18, type 2a
chr21_-_25612658 0.04 ENSDART00000115276
fibroblast growth factor (acidic) intracellular binding protein b
chr11_-_37509001 0.04 ENSDART00000109753
bassoon (presynaptic cytomatrix protein) b
chr3_-_61362398 0.03 ENSDART00000156177
si:dkey-111k8.3
chr16_-_26074529 0.03 ENSDART00000148653
ENSDART00000148923
transmembrane protein 145
chr10_+_38526496 0.03 ENSDART00000144329
alkaline ceramidase 3
chr16_-_11859309 0.03 ENSDART00000145754
chemokine (C-X-C motif) receptor 3, tandem duplicate 1
chr2_-_3045861 0.03 ENSDART00000105818
ENSDART00000187575
guanylate kinase 1a
chr13_-_42400647 0.03 ENSDART00000043069
membrane-associated ring finger (C3HC4) 5
chr1_+_144284 0.03 ENSDART00000064061
protein Z, vitamin K-dependent plasma glycoprotein b
chr13_-_16066997 0.03 ENSDART00000184790
spermatogenesis associated 48
chr18_-_1185772 0.03 ENSDART00000143245
neuroplastin b
chr15_+_31332552 0.03 ENSDART00000134933
ENSDART00000173915
odorant receptor, family F, subfamily 119, member 2
chr7_-_17779644 0.03 ENSDART00000128504
si:dkey-106g10.7
chr4_+_11695979 0.03 ENSDART00000137736
muskelin 1, intracellular mediator containing kelch motifs
chr9_+_29430432 0.03 ENSDART00000125632
UDP-glucose glycoprotein glucosyltransferase 2
chr6_-_35046735 0.03 ENSDART00000143649
UDP-N-acetylglucosamine pyrophosphorylase 1
chr10_+_2899108 0.02 ENSDART00000147031
endoplasmic reticulum aminopeptidase 1a
chr14_+_29941445 0.02 ENSDART00000181761
family with sequence similarity 149 member A
chr6_-_12172424 0.02 ENSDART00000109344
tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 1a
chr15_+_43398317 0.02 ENSDART00000182528
ENSDART00000172154
ENSDART00000187688
actinin, alpha 4
chr5_-_38155005 0.02 ENSDART00000097770
guanylate cyclase 2D, retinal
chr6_+_27146671 0.02 ENSDART00000156792
kinesin family member 1Aa
chr20_-_18736281 0.02 ENSDART00000142837
ectonucleotide pyrophosphatase/phosphodiesterase 5
chr1_+_25801648 0.02 ENSDART00000129471
guanylate cyclase 1 soluble subunit beta 1
chr3_-_1970820 0.02 ENSDART00000136467
si:ch211-254c8.3
chr17_+_28706946 0.02 ENSDART00000126967
striatin, calmodulin binding protein 3
chr1_+_10318089 0.02 ENSDART00000029774
phosphatidylinositol-4,5-bisphosphate 4-phosphatase 1b
chr8_+_44714336 0.02 ENSDART00000145801
ELMO/CED-12 domain containing 3
chr16_+_11242443 0.02 ENSDART00000024935
glycogen synthase kinase 3 alpha b
chr3_-_33574576 0.02 ENSDART00000184881

chr13_+_36622100 0.02 ENSDART00000133198
si:ch211-67f24.7
chr14_-_32959851 0.02 ENSDART00000075157
cysteine-rich hydrophobic domain 1
chr19_-_5103141 0.02 ENSDART00000150952
triosephosphate isomerase 1a
chr11_-_42918971 0.01 ENSDART00000052912
protocadherin 20
chr20_-_37813863 0.01 ENSDART00000147529
basic leucine zipper transcription factor, ATF-like 3
chr3_-_32169754 0.01 ENSDART00000179010
troponin T type 1 (skeletal, slow)
chr16_-_28091597 0.01 ENSDART00000166595

chr8_-_13454281 0.01 ENSDART00000141959

chr15_+_14826966 0.01 ENSDART00000157912
ENSDART00000171133
odorant receptor, family H, subfamily 130, member 1
chr9_+_38088331 0.01 ENSDART00000123749
calcium channel, voltage-dependent, beta 4a subunit
chr18_+_2228737 0.01 ENSDART00000165301
RAB27A, member RAS oncogene family
chr16_-_12173554 0.01 ENSDART00000110567
ENSDART00000155935
calsyntenin 3
chr7_-_18416741 0.01 ENSDART00000097882
somatostatin receptor 1b
chr12_+_17154655 0.01 ENSDART00000028003
ankyrin repeat domain 22
chr4_-_28335184 0.01 ENSDART00000178149
ENSDART00000043737
cadherin EGF LAG seven-pass G-type receptor 1a
chr7_+_25059845 0.01 ENSDART00000077215
protein phosphatase 2, regulatory subunit B', beta
chr21_+_43328685 0.01 ENSDART00000109620
ENSDART00000139668
septin 8a
chr9_-_43082945 0.00 ENSDART00000142257
coiled-coil domain containing 141
chr14_+_46287296 0.00 ENSDART00000183620
calcium binding protein 2b
chr15_+_5280858 0.00 ENSDART00000174242
odorant receptor, family E, subfamily 121, member 1
chr13_+_31177934 0.00 ENSDART00000144568
protein tyrosine phosphatase, non-receptor type 20
chr16_-_40043322 0.00 ENSDART00000145278
si:dkey-29b11.3
chr22_+_2403068 0.00 ENSDART00000132925
ENSDART00000132569
zgc:112977
chr6_-_40466861 0.00 ENSDART00000062724
cereblon

Network of associatons between targets according to the STRING database.

First level regulatory network of pou4f2

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.4 GO:1902292 cell cycle DNA replication initiation(GO:1902292) nuclear cell cycle DNA replication initiation(GO:1902315) mitotic DNA replication initiation(GO:1902975)
0.0 0.4 GO:0000185 activation of MAPKKK activity(GO:0000185)
0.0 0.1 GO:1902895 pri-miRNA transcription from RNA polymerase II promoter(GO:0061614) regulation of pri-miRNA transcription from RNA polymerase II promoter(GO:1902893) positive regulation of pri-miRNA transcription from RNA polymerase II promoter(GO:1902895)
0.0 0.1 GO:0070987 error-free translesion synthesis(GO:0070987)
0.0 0.1 GO:0071361 cellular response to ethanol(GO:0071361)
0.0 0.1 GO:0038083 peptidyl-tyrosine autophosphorylation(GO:0038083)
0.0 0.3 GO:2000272 negative regulation of receptor activity(GO:2000272)
0.0 0.1 GO:1904871 positive regulation of protein localization to nucleus(GO:1900182) regulation of protein localization to Cajal body(GO:1904869) positive regulation of protein localization to Cajal body(GO:1904871)
0.0 0.1 GO:0090069 regulation of ribosome biogenesis(GO:0090069)
0.0 0.1 GO:0071236 cellular response to antibiotic(GO:0071236) cellular response to toxic substance(GO:0097237)
0.0 0.1 GO:0045948 positive regulation of translational initiation(GO:0045948)
0.0 0.0 GO:0070920 regulation of production of small RNA involved in gene silencing by RNA(GO:0070920) regulation of production of miRNAs involved in gene silencing by miRNA(GO:1903798)
0.0 0.1 GO:0009972 cytidine catabolic process(GO:0006216) cytidine deamination(GO:0009972) cytidine metabolic process(GO:0046087)
0.0 0.1 GO:0060967 negative regulation of posttranscriptional gene silencing(GO:0060149) negative regulation of gene silencing by miRNA(GO:0060965) negative regulation of gene silencing by RNA(GO:0060967)
0.0 0.1 GO:0071596 ubiquitin-dependent protein catabolic process via the N-end rule pathway(GO:0071596)
0.0 0.2 GO:0019883 antigen processing and presentation of endogenous peptide antigen(GO:0002483) antigen processing and presentation of endogenous antigen(GO:0019883) antigen processing and presentation of endogenous peptide antigen via MHC class I(GO:0019885)
0.0 0.1 GO:0036149 phosphatidylinositol acyl-chain remodeling(GO:0036149)
0.0 0.1 GO:0046166 methylglyoxal biosynthetic process(GO:0019242) glyceraldehyde-3-phosphate biosynthetic process(GO:0046166)
0.0 0.1 GO:0034975 protein folding in endoplasmic reticulum(GO:0034975)
0.0 0.1 GO:0098974 postsynaptic actin cytoskeleton organization(GO:0098974)
0.0 0.1 GO:0060976 coronary vasculature development(GO:0060976)
0.0 0.1 GO:0035889 otolith tethering(GO:0035889)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.1 GO:0044316 cone cell pedicle(GO:0044316)
0.0 0.1 GO:0043073 germ cell nucleus(GO:0043073)
0.0 0.4 GO:0042555 MCM complex(GO:0042555)
0.0 0.0 GO:0070578 RISC-loading complex(GO:0070578)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.1 GO:0004809 tRNA (guanine-N2-)-methyltransferase activity(GO:0004809)
0.0 0.1 GO:0004807 triose-phosphate isomerase activity(GO:0004807) methylglyoxal synthase activity(GO:0008929)
0.0 0.4 GO:0003688 DNA replication origin binding(GO:0003688)
0.0 0.1 GO:0016934 extracellular-glycine-gated ion channel activity(GO:0016933) extracellular-glycine-gated chloride channel activity(GO:0016934)
0.0 0.0 GO:0070883 pre-miRNA binding(GO:0070883)

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.1 REACTOME CS DS DEGRADATION Genes involved in CS/DS degradation