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PRJNA195909:zebrafish embryo and larva development

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Results for pou3f1

Z-value: 2.08

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Transcription factors associated with pou3f1

Gene Symbol Gene ID Gene Info
ENSDARG00000009823 POU class 3 homeobox 1
ENSDARG00000112302 POU class 3 homeobox 1

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
pou3f1dr11_v1_chr16_+_33593116_335931160.941.6e-04Click!

Activity profile of pou3f1 motif

Sorted Z-values of pou3f1 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr23_-_31372639 6.48 ENSDART00000179908
ENSDART00000135620
ENSDART00000053367
high mobility group nucleosomal binding domain 3
chr6_+_4539953 4.97 ENSDART00000025031
POU class 4 homeobox 1
chr3_-_32817274 4.78 ENSDART00000142582
myosin light chain, phosphorylatable, fast skeletal muscle a
chr21_+_30563115 3.98 ENSDART00000028566
si:ch211-200p22.4
chr21_+_26390549 3.74 ENSDART00000185643
thymosin, beta
chr9_+_54178475 3.34 ENSDART00000104475
thymosin, beta 4 x
chr23_+_21473103 3.22 ENSDART00000142921
si:ch73-21g5.7
chr2_+_55982940 3.20 ENSDART00000097753
ENSDART00000097751
nicotinamide riboside kinase 2
chr4_-_16406737 3.02 ENSDART00000013085
decorin
chr8_+_13503377 2.98 ENSDART00000034740
ENSDART00000167187
fucosyltransferase 9d
chr13_+_33117528 2.96 ENSDART00000085719
si:ch211-10a23.2
chr7_-_24699985 2.94 ENSDART00000052802
calbindin 2b
chr1_+_54013457 2.93 ENSDART00000012104
ENSDART00000126339
deltaA
chr9_-_33877476 2.89 ENSDART00000150035
ENSDART00000088441
ENSDART00000183210
si:ch73-147f11.1
chr17_+_33719415 2.83 ENSDART00000132294
fucosyltransferase 8a (alpha (1,6) fucosyltransferase)
chr9_-_18877597 2.77 ENSDART00000099446
potassium channel tetramerization domain containing 4
chr1_+_46194333 2.74 ENSDART00000010894
SRY (sex determining region Y)-box 1b
chr3_-_5964557 2.74 ENSDART00000184738

chr19_+_3653976 2.73 ENSDART00000125673
neural precursor cell expressed, developmentally down-regulated 9
chr3_+_23743139 2.71 ENSDART00000187409
homeobox B3a
chr7_+_40228422 2.66 ENSDART00000052222
protein tyrosine phosphatase, receptor type, N polypeptide 2
chr4_-_9592402 2.65 ENSDART00000114060
cerebral dopamine neurotrophic factor
chr5_-_42272517 2.64 ENSDART00000137692
ENSDART00000164363
si:ch211-207c6.2
chr22_+_5106751 2.57 ENSDART00000138967
ataxia, cerebellar, Cayman type a
chr18_+_38749547 2.56 ENSDART00000143735
si:ch211-215d8.2
chr20_+_40150612 2.56 ENSDART00000143680
ENSDART00000109681
ENSDART00000101041
ENSDART00000121818
triadin
chr25_+_34576067 2.48 ENSDART00000157519
transient receptor potential cation channel, subfamily M, member 1b
chr19_+_19759577 2.39 ENSDART00000169480
homeobox A5a
chr23_+_36771593 2.35 ENSDART00000078240
membrane-associated ring finger (C3HC4) 9
chr10_+_32104305 2.32 ENSDART00000099880
wingless-type MMTV integration site family, member 11, related
chr13_+_29778610 2.26 ENSDART00000132004
paired box 2a
chr23_-_3409140 2.24 ENSDART00000002309
v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog Ba
chr5_+_58550291 2.22 ENSDART00000184983
ENSDART00000044803
POU class 2 homeobox 3
chr22_+_15624371 2.18 ENSDART00000124868
lipoprotein lipase
chr19_+_19775757 2.17 ENSDART00000164677
homeobox A3a
chr13_+_30951155 2.05 ENSDART00000057469
ENSDART00000162254
V-set and transmembrane domain containing 4a
chr16_-_12173554 2.04 ENSDART00000110567
ENSDART00000155935
calsyntenin 3
chr19_-_2318391 2.03 ENSDART00000012791
sp8 transcription factor a
chr18_+_44649804 1.96 ENSDART00000059063
EH-domain containing 2b
chr13_-_6081803 1.96 ENSDART00000099224
deltaD
chr21_+_41743493 1.94 ENSDART00000192669
protein phosphatase 2, regulatory subunit B, beta b
chr5_-_25406807 1.93 ENSDART00000089748
RAR-related orphan receptor B
chr19_+_19786117 1.92 ENSDART00000167757
ENSDART00000163546
homeobox A1a
chr25_-_15045338 1.87 ENSDART00000161165
ENSDART00000165774
ENSDART00000172538
paired box 6a
chr23_+_28731379 1.86 ENSDART00000047378
cortistatin
chr5_-_24000211 1.85 ENSDART00000188865
MAP7 domain containing 2a
chr6_-_13187168 1.83 ENSDART00000193286
ENSDART00000188350
ENSDART00000150036
ENSDART00000149940
ADAM metallopeptidase domain 23a
chr3_+_23697997 1.83 ENSDART00000184299
ENSDART00000078466
homeobox B3a
chr19_+_3001473 1.83 ENSDART00000145363
scleraxis bHLH transcription factor a
chr17_-_32865788 1.80 ENSDART00000077476
prospero homeobox 1a
chr22_+_20195280 1.76 ENSDART00000088603
ENSDART00000135692
si:dkey-110c1.7
chr23_-_20258490 1.74 ENSDART00000147326
laminin, beta 2 (laminin S)
chr9_-_21507083 1.73 ENSDART00000137922
AF4/FMR2 family, member 3
chr3_+_23742868 1.69 ENSDART00000153512
homeobox B3a
chr13_-_33822550 1.68 ENSDART00000143703
fibronectin leucine rich transmembrane 3
chr7_-_39537292 1.67 ENSDART00000173965
otogelin
chr1_+_7679328 1.66 ENSDART00000163488
ENSDART00000190070
engrailed homeobox 1b
chr18_+_22606259 1.66 ENSDART00000128965
breast cancer anti-estrogen resistance 1
chr20_+_48782068 1.65 ENSDART00000159275
NK2 homeobox 2b
chr7_+_25920792 1.65 ENSDART00000026295
arrestin, beta 2b
chr14_+_36889893 1.64 ENSDART00000124159
si:ch211-132p1.3
chr14_-_26704829 1.62 ENSDART00000078563
neurogenin 1
chr10_+_22003750 1.61 ENSDART00000109420
Kv channel interacting protein 1 b
chr6_+_41096058 1.61 ENSDART00000028373
FK506 binding protein 5
chr25_-_13188678 1.58 ENSDART00000125754
si:ch211-147m6.1
chr18_+_29402623 1.58 ENSDART00000014703
v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog a (paralog a)
chr18_-_36135799 1.56 ENSDART00000059344
beta-1,3-glucuronyltransferase 1 (glucuronosyltransferase P) a
chr23_+_26733232 1.55 ENSDART00000035080
zgc:158263
chr23_+_28582865 1.54 ENSDART00000020296
L1 cell adhesion molecule, paralog a
chr6_-_13188667 1.53 ENSDART00000191654
ADAM metallopeptidase domain 23a
chr4_+_31259 1.53 ENSDART00000166826
putative homeodomain transcription factor 2
chr14_-_40389699 1.52 ENSDART00000181581
ENSDART00000173398
protocadherin 19
chr23_-_3408777 1.50 ENSDART00000193245
v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog Ba
chr11_+_25257022 1.50 ENSDART00000156052
tumor protein p53 inducible nuclear protein 2
chr20_-_39735952 1.46 ENSDART00000101049
ENSDART00000137485
ENSDART00000062402
tumor protein D52-like 1
chr19_+_2726819 1.42 ENSDART00000187122
ENSDART00000112414
Rap guanine nucleotide exchange factor (GEF) 5a
chr11_-_44876005 1.39 ENSDART00000192006
opsin 6, group member a
chr21_-_35853245 1.38 ENSDART00000172245
sarcoglycan, delta (dystrophin-associated glycoprotein)
chr8_+_28593707 1.38 ENSDART00000097213
transcription factor 15
chr20_-_39188476 1.35 ENSDART00000152858
regulator of calcineurin 2
chr13_+_28705143 1.30 ENSDART00000183338
LIM domain binding 1a
chr7_-_4036184 1.30 ENSDART00000019949
NDRG family member 2
chr5_+_29820266 1.29 ENSDART00000146331
ENSDART00000098315
F11 receptor, tandem duplicate 2
chr18_+_29403017 1.27 ENSDART00000176966
v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog a (paralog a)
chr16_+_43152727 1.26 ENSDART00000125590
ENSDART00000154493
ADAM metallopeptidase domain 22
chr16_-_12173399 1.26 ENSDART00000142574
calsyntenin 3
chr17_-_42213822 1.25 ENSDART00000187904
ENSDART00000180029
NK2 homeobox 2a
chr19_-_30562648 1.25 ENSDART00000171006
hippocalcin like 4
chr10_+_36458563 1.25 ENSDART00000077008
arachidonate 5-lipoxygenase-activating protein
chr19_+_14573998 1.24 ENSDART00000022076
family with sequence similarity 46, member Bb
chr8_-_12403077 1.24 ENSDART00000142150
PHD finger protein 19
chr2_+_52847049 1.23 ENSDART00000121980
cAMP responsive element binding protein 3-like 3b
chr17_-_37052622 1.23 ENSDART00000186408
DNA (cytosine-5-)-methyltransferase 3 alpha b
chr1_-_17587552 1.22 ENSDART00000039917
acyl-CoA synthetase long chain family member 1a
chr5_+_22970617 1.21 ENSDART00000192859
high mobility group nucleosomal binding domain 7
chr19_-_28367413 1.20 ENSDART00000079092
si:dkey-261i16.5
chr4_+_12013043 1.20 ENSDART00000130692
cryptochrome circadian clock 1aa
chr13_-_7031033 1.15 ENSDART00000193211

chr9_-_1984604 1.15 ENSDART00000082339
homeobox D12a
chr21_+_5888641 1.11 ENSDART00000091331
proline dehydrogenase (oxidase) 1a
chr10_+_33895315 1.11 ENSDART00000142881
furry homolog b (Drosophila)
chr14_-_48939560 1.10 ENSDART00000021736
short coiled-coil protein b
chr11_+_25634041 1.10 ENSDART00000033657
glutamate receptor, metabotropic 6b
chr7_-_30367650 1.07 ENSDART00000075519
aldehyde dehydrogenase 1 family, member A2
chr24_-_8730913 1.06 ENSDART00000187228
ENSDART00000082349
ENSDART00000186660
transcription factor AP-2 alpha
chr15_-_18361475 1.05 ENSDART00000155866
zinc finger and BTB domain containing 16b
chr18_-_42830563 1.05 ENSDART00000191488
tetratricopeptide repeat domain 36
chr9_-_9980704 1.04 ENSDART00000130243
ENSDART00000193475
UDP glucuronosyltransferase 1 family a, b
chr12_-_38548299 1.04 ENSDART00000153374
si:dkey-1f1.3
chr5_-_46896541 1.04 ENSDART00000133240
EGF-like repeats and discoidin I-like domains 3a
chr6_-_16406210 1.03 ENSDART00000012023
Fas apoptotic inhibitory molecule b
chr12_+_23424108 1.03 ENSDART00000077732
BMP and activin membrane-bound inhibitor (Xenopus laevis) homolog a
chr4_+_12013642 1.03 ENSDART00000067281
cryptochrome circadian clock 1aa
chr25_-_25736958 1.02 ENSDART00000166308
calcium and integrin binding family member 2
chr13_+_29773153 1.01 ENSDART00000144443
ENSDART00000133796
ENSDART00000141310
ENSDART00000139782
paired box 2a
chr21_-_5393125 1.00 ENSDART00000146061
proteasome 26S subunit, non-ATPase 5
chr21_+_38817785 1.00 ENSDART00000177616
ENSDART00000149085
HNF1 homeobox Bb
chr22_+_17784414 0.99 ENSDART00000188189
ENSDART00000145260
transmembrane 6 superfamily member 2
chr3_-_32337653 0.98 ENSDART00000156918
ENSDART00000156551
si:dkey-16p21.8
chr25_-_16057539 0.96 ENSDART00000090388
cytochrome b5 reductase 2
chr6_+_16406723 0.92 ENSDART00000040035
coiled-coil domain containing 80 like 1
chr3_+_47322494 0.91 ENSDART00000102202
phosphatidic acid phosphatase type 2D
chr15_-_16012963 0.90 ENSDART00000144138
HNF1 homeobox Ba
chr1_+_26411496 0.88 ENSDART00000112263
Rho guanine nucleotide exchange factor (GEF) 38
chr7_+_61050329 0.87 ENSDART00000115355
NACHT and WD repeat domain containing 2
chr10_+_31248036 0.87 ENSDART00000193574
roundabout, axon guidance receptor, homolog 4 (Drosophila)
chr8_+_28469054 0.86 ENSDART00000062716
solute carrier family 52 (riboflavin transporter), member 3
chr10_-_27196093 0.85 ENSDART00000185282
autism susceptibility candidate 2a
chr20_+_35998073 0.84 ENSDART00000140457
opsin 5
chr6_+_23935045 0.84 ENSDART00000162993
growth arrest and DNA-damage-inducible, alpha, b
chr1_+_1599979 0.83 ENSDART00000097626
urotensin II-related peptide
chr14_-_28001986 0.83 ENSDART00000054115
TSC22 domain family, member 3
chr16_-_31756859 0.82 ENSDART00000149170
ENSDART00000126617
ENSDART00000182722
protein tyrosine phosphatase, non-receptor type 6
chr7_+_69470442 0.81 ENSDART00000189593
GABA(A) receptor-associated protein b
chr23_+_44307996 0.81 ENSDART00000042430
discs, large homolog 4b (Drosophila)
chr22_-_32392252 0.81 ENSDART00000148681
ENSDART00000137945
poly(rC) binding protein 4
chr4_-_11580948 0.80 ENSDART00000049066
neuroepithelial cell transforming 1
chr22_-_18491813 0.79 ENSDART00000105419
si:ch211-212d10.2
chr24_+_25467465 0.79 ENSDART00000189933
small muscle protein, X-linked
chr7_+_60396957 0.79 ENSDART00000121545
breast cancer metastasis suppressor 1
chr10_+_453619 0.78 ENSDART00000135598
zinc finger, DHHC-type containing 8a
chr15_-_14212777 0.78 ENSDART00000165572

chr2_-_34555945 0.78 ENSDART00000056671
bone morphogenetic protein/retinoic acid inducible neural-specific 2
chr17_+_15882533 0.77 ENSDART00000164124
gamma-aminobutyric acid (GABA) A receptor, rho 2a
chr23_+_21380079 0.74 ENSDART00000089379
intermediate filament family orphan 2a
chr1_+_5275811 0.74 ENSDART00000189676
sprouty RTK signaling antagonist 2
chr15_+_39096736 0.73 ENSDART00000129511
ENSDART00000014877
roundabout, axon guidance receptor, homolog 2 (Drosophila)
chr5_-_54497319 0.72 ENSDART00000160492
aminolevulinate dehydratase
chr12_-_34887943 0.72 ENSDART00000027379
BRD4 interacting chromatin remodeling complex associated protein like
chr1_-_12109216 0.71 ENSDART00000079930
microsomal triglyceride transfer protein
chr25_-_6557854 0.70 ENSDART00000181740
chondroitin sulfate proteoglycan 4
chr15_+_45640906 0.68 ENSDART00000149361
ENSDART00000149079
S-antigen; retina and pineal gland (arrestin) b
chr22_-_11729350 0.68 ENSDART00000105813
keratin 222
chr23_+_11347313 0.67 ENSDART00000135406
cell adhesion molecule L1-like a
chr2_+_30147504 0.66 ENSDART00000190947
potassium voltage-gated channel, Shab-related subfamily, member 2
chr12_+_2677303 0.66 ENSDART00000093113
anthrax toxin receptor 1c
chr14_-_34700633 0.65 ENSDART00000150358
actin binding LIM protein family, member 3
chr18_-_49286381 0.65 ENSDART00000174248
ENSDART00000174038
si:zfos-464b6.2
chr8_-_15398760 0.64 ENSDART00000162011
ATP/GTP binding protein-like 4
chr2_+_33382648 0.64 ENSDART00000137207
ENSDART00000098831
solute carrier family 6 (neurotransmitter transporter, glycine), member 9
chr17_-_24916889 0.64 ENSDART00000156157
si:ch211-195o20.7
chr3_-_31783737 0.63 ENSDART00000090809
potassium voltage-gated channel, subfamily H (eag-related), member 6a
chr11_-_35575791 0.63 ENSDART00000031441
ENSDART00000188513
ENSDART00000183609
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3Fb
chr25_+_36674715 0.62 ENSDART00000111861
v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog b (paralog b)
chr19_-_6239248 0.62 ENSDART00000014127
POU class 2 homeobox 2a
chr5_-_24238733 0.62 ENSDART00000138170
phospholipid scramblase 3a
chr25_+_19666621 0.60 ENSDART00000112746
zgc:171459
chr16_+_25535993 0.60 ENSDART00000077436
myosin regulatory light chain interacting protein b
chr1_-_20593778 0.59 ENSDART00000124770
UDP glycosyltransferase 8
chr2_-_24317240 0.58 ENSDART00000078975
tRNA selenocysteine 1 associated protein 1b
chr17_-_30473374 0.58 ENSDART00000155021
si:ch211-175f11.5
chr2_+_32835679 0.57 ENSDART00000132767
PX domain containing 1a
chr5_-_16996482 0.57 ENSDART00000144501
polypeptide N-acetylgalactosaminyltransferase 9
chr22_+_5135884 0.56 ENSDART00000141276
myeloid-derived growth factor
chr16_+_40560622 0.56 ENSDART00000038294
tumor protein p53 inducible nuclear protein 1
chr1_-_1402303 0.54 ENSDART00000130697
runt-related transcription factor 1
chr4_+_20255160 0.54 ENSDART00000188658
leucine-rich repeats and transmembrane domains 2a
chr7_-_38633867 0.54 ENSDART00000137424
C1q and TNF related 4
chr18_+_7286788 0.53 ENSDART00000022998
si:ch73-86n2.1
chr20_-_25626693 0.53 ENSDART00000132247
phosphoribosylaminoimidazole carboxylase, phosphoribosylaminoimidazole succinocarboxamide synthetase
chr16_+_45746549 0.53 ENSDART00000190403
progestin and adipoQ receptor family member VI
chr7_-_40738774 0.52 ENSDART00000084179
ring finger protein 32
chr16_-_21620947 0.52 ENSDART00000115011
ENSDART00000183125
ENSDART00000188856
ENSDART00000189460
discoidin domain receptor tyrosine kinase 1
chr23_-_1017605 0.51 ENSDART00000138290
cadherin 26, tandem duplicate 1
chr5_-_63302944 0.51 ENSDART00000047110
gelsolin b
chr10_-_24689280 0.50 ENSDART00000191476
si:ch211-287a12.9
chr10_-_5821584 0.50 ENSDART00000166388
interleukin 6 signal transducer
chr1_+_31725154 0.49 ENSDART00000112333
ENSDART00000189801
cyclin and CBS domain divalent metal cation transport mediator 2b
chr24_+_41931585 0.48 ENSDART00000130310
erythrocyte membrane protein band 4.1-like 3a
chr14_-_12391506 0.46 ENSDART00000080864
magnesium transporter 1
chr3_+_33345348 0.46 ENSDART00000059262
membrane protein, palmitoylated 2a (MAGUK p55 subfamily member 2)
chr2_-_56131312 0.45 ENSDART00000097755
JunD proto-oncogene, AP-1 transcription factor subunit
chr23_+_32011768 0.45 ENSDART00000053509
pleiomorphic adenoma gene X
chr1_+_27825980 0.44 ENSDART00000160524
paraspeckle component 1
chr7_-_23873173 0.44 ENSDART00000101408
zgc:162171
chr5_+_38837429 0.44 ENSDART00000160236
Fraser extracellular matrix complex subunit 1
chr5_+_30624183 0.43 ENSDART00000141444
ATP-binding cassette, sub-family G (WHITE), member 4a
chr21_-_27185915 0.42 ENSDART00000135052
solute carrier family 8 (sodium/calcium exchanger), member 4a
chr3_-_50998577 0.41 ENSDART00000157735
CDC42 effector protein (Rho GTPase binding) 4a
chr24_-_32452355 0.41 ENSDART00000146511
coiled-coil domain containing 129

Network of associatons between targets according to the STRING database.

First level regulatory network of pou3f1

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
2.2 6.5 GO:0035773 insulin secretion involved in cellular response to glucose stimulus(GO:0035773) regulation of insulin secretion involved in cellular response to glucose stimulus(GO:0061178)
0.9 3.7 GO:0043152 induction of bacterial agglutination(GO:0043152)
0.9 3.7 GO:0021742 abducens nucleus development(GO:0021742)
0.9 4.4 GO:0090527 actin filament reorganization(GO:0090527)
0.7 2.9 GO:1900271 regulation of presynaptic cytosolic calcium ion concentration(GO:0099509) regulation of long-term synaptic potentiation(GO:1900271)
0.6 1.8 GO:0035992 tendon formation(GO:0035992)
0.6 1.7 GO:0008344 adult locomotory behavior(GO:0008344)
0.5 5.2 GO:0034672 anterior/posterior pattern specification involved in pronephros development(GO:0034672) anterior/posterior pattern specification involved in kidney development(GO:0072098)
0.5 3.9 GO:0042989 sequestering of actin monomers(GO:0042989)
0.5 2.9 GO:0055016 hypochord development(GO:0055016)
0.4 1.3 GO:0021530 spinal cord oligodendrocyte cell fate specification(GO:0021530)
0.4 1.7 GO:1900120 regulation of cytokine activity(GO:0060300) regulation of receptor binding(GO:1900120) regulation of chemokine activity(GO:1900136)
0.4 2.0 GO:0021523 somatic motor neuron differentiation(GO:0021523)
0.4 3.3 GO:0051965 positive regulation of synapse assembly(GO:0051965)
0.4 5.8 GO:0036065 fucosylation(GO:0036065)
0.3 1.6 GO:0021516 dorsal spinal cord development(GO:0021516) anterior lateral line nerve development(GO:0048909)
0.3 2.2 GO:0060017 parathyroid gland development(GO:0060017)
0.3 1.8 GO:0099525 synaptic vesicle docking(GO:0016081) presynaptic dense core granule exocytosis(GO:0099525)
0.3 0.9 GO:0001954 positive regulation of cell-matrix adhesion(GO:0001954)
0.3 0.8 GO:0097113 AMPA glutamate receptor clustering(GO:0097113) glutamate receptor clustering(GO:0097688)
0.3 1.1 GO:0061113 pancreas morphogenesis(GO:0061113)
0.3 1.9 GO:0060221 retinal rod cell differentiation(GO:0060221)
0.3 1.0 GO:0007638 mechanosensory behavior(GO:0007638)
0.2 1.2 GO:0019370 leukotriene metabolic process(GO:0006691) leukotriene biosynthetic process(GO:0019370)
0.2 2.6 GO:0006798 polyphosphate metabolic process(GO:0006797) polyphosphate catabolic process(GO:0006798)
0.2 1.1 GO:0010133 proline catabolic process to glutamate(GO:0010133)
0.2 0.8 GO:0016038 absorption of visible light(GO:0016038)
0.2 5.6 GO:0010508 positive regulation of autophagy(GO:0010508)
0.2 2.4 GO:0060385 axonogenesis involved in innervation(GO:0060385)
0.2 1.9 GO:0070262 peptidyl-serine dephosphorylation(GO:0070262)
0.2 0.8 GO:0033119 negative regulation of RNA splicing(GO:0033119) negative regulation of mRNA splicing, via spliceosome(GO:0048025)
0.2 0.6 GO:0060092 regulation of synaptic transmission, glycinergic(GO:0060092)
0.2 0.6 GO:0060306 regulation of membrane repolarization(GO:0060306) regulation of ventricular cardiac muscle cell membrane repolarization(GO:0060307) regulation of cardiac muscle cell membrane repolarization(GO:0099623) ventricular cardiac muscle cell membrane repolarization(GO:0099625)
0.2 1.7 GO:0016203 muscle attachment(GO:0016203)
0.2 1.7 GO:0021508 floor plate formation(GO:0021508) floor plate morphogenesis(GO:0033505)
0.1 0.9 GO:0032218 riboflavin transport(GO:0032218)
0.1 0.5 GO:0010755 regulation of collagen metabolic process(GO:0010712) regulation of plasminogen activation(GO:0010755) regulation of collagen biosynthetic process(GO:0032965) regulation of multicellular organismal metabolic process(GO:0044246) regulation of cardiac muscle tissue growth(GO:0055021) regulation of cardiac muscle cell proliferation(GO:0060043)
0.1 3.9 GO:0016185 synaptic vesicle budding from presynaptic endocytic zone membrane(GO:0016185)
0.1 2.2 GO:0019433 triglyceride catabolic process(GO:0019433)
0.1 0.5 GO:0070572 positive regulation of axon regeneration(GO:0048680) positive regulation of neuron projection regeneration(GO:0070572)
0.1 1.4 GO:0007525 somatic muscle development(GO:0007525)
0.1 0.9 GO:0002031 G-protein coupled receptor internalization(GO:0002031)
0.1 2.7 GO:0021884 forebrain neuron development(GO:0021884)
0.1 0.3 GO:0045648 positive regulation of erythrocyte differentiation(GO:0045648)
0.1 1.1 GO:0050908 detection of light stimulus involved in visual perception(GO:0050908) detection of light stimulus involved in sensory perception(GO:0050962)
0.1 0.5 GO:0051963 regulation of synapse assembly(GO:0051963)
0.1 1.0 GO:1902042 regulation of extrinsic apoptotic signaling pathway via death domain receptors(GO:1902041) negative regulation of extrinsic apoptotic signaling pathway via death domain receptors(GO:1902042)
0.1 0.8 GO:0000185 activation of MAPKKK activity(GO:0000185)
0.1 1.8 GO:0071542 dopaminergic neuron differentiation(GO:0071542)
0.1 1.3 GO:0050892 intestinal absorption(GO:0050892)
0.1 0.1 GO:0032816 regulation of natural killer cell activation(GO:0032814) positive regulation of natural killer cell activation(GO:0032816)
0.1 0.7 GO:0001579 medium-chain fatty acid transport(GO:0001579)
0.1 0.8 GO:0007084 mitotic nuclear envelope reassembly(GO:0007084)
0.1 1.1 GO:0014034 neural crest cell fate commitment(GO:0014034) neural crest cell fate specification(GO:0014036)
0.1 1.1 GO:0032481 positive regulation of type I interferon production(GO:0032481)
0.1 0.8 GO:0071941 nitrogen cycle metabolic process(GO:0071941)
0.1 0.8 GO:0071300 cellular response to retinoic acid(GO:0071300)
0.1 0.7 GO:0070373 negative regulation of ERK1 and ERK2 cascade(GO:0070373)
0.1 0.7 GO:1901998 toxin transport(GO:1901998)
0.1 1.5 GO:2001235 positive regulation of apoptotic signaling pathway(GO:2001235)
0.1 1.0 GO:0043248 proteasome assembly(GO:0043248)
0.1 1.5 GO:0045773 positive regulation of axon extension(GO:0045773)
0.1 1.6 GO:0050650 chondroitin sulfate proteoglycan biosynthetic process(GO:0050650)
0.1 0.4 GO:0031670 cellular response to nutrient(GO:0031670) vitamin D3 metabolic process(GO:0070640) cellular response to vitamin(GO:0071295) cellular response to vitamin D(GO:0071305)
0.1 1.6 GO:0000413 protein peptidyl-prolyl isomerization(GO:0000413)
0.0 0.1 GO:0034134 toll-like receptor 2 signaling pathway(GO:0034134)
0.0 1.2 GO:0035338 long-chain fatty-acyl-CoA biosynthetic process(GO:0035338)
0.0 2.5 GO:0051262 protein tetramerization(GO:0051262)
0.0 1.0 GO:0006825 copper ion transport(GO:0006825)
0.0 0.1 GO:0045649 regulation of macrophage differentiation(GO:0045649)
0.0 0.8 GO:0006995 cellular response to nitrogen starvation(GO:0006995) cellular response to nitrogen levels(GO:0043562)
0.0 1.0 GO:0032474 otolith morphogenesis(GO:0032474)
0.0 1.0 GO:0030168 platelet activation(GO:0030168)
0.0 0.4 GO:0031272 pseudopodium organization(GO:0031268) pseudopodium assembly(GO:0031269) regulation of pseudopodium assembly(GO:0031272) positive regulation of pseudopodium assembly(GO:0031274)
0.0 1.2 GO:0006305 DNA alkylation(GO:0006305) DNA methylation(GO:0006306)
0.0 0.4 GO:0042044 fluid transport(GO:0042044)
0.0 1.7 GO:0001841 neural tube formation(GO:0001841)
0.0 1.5 GO:0016126 sterol biosynthetic process(GO:0016126)
0.0 0.4 GO:0070189 kynurenine metabolic process(GO:0070189)
0.0 0.6 GO:0001938 positive regulation of endothelial cell proliferation(GO:0001938)
0.0 1.4 GO:0007602 phototransduction(GO:0007602)
0.0 0.8 GO:0010669 epithelial structure maintenance(GO:0010669)
0.0 0.5 GO:0018279 protein N-linked glycosylation via asparagine(GO:0018279)
0.0 0.7 GO:0030513 positive regulation of BMP signaling pathway(GO:0030513)
0.0 0.2 GO:0046850 regulation of bone remodeling(GO:0046850)
0.0 2.3 GO:0051260 protein homooligomerization(GO:0051260)
0.0 0.1 GO:0046391 5-phosphoribose 1-diphosphate biosynthetic process(GO:0006015) 5-phosphoribose 1-diphosphate metabolic process(GO:0046391)
0.0 6.9 GO:0009952 anterior/posterior pattern specification(GO:0009952)
0.0 0.4 GO:0048382 mesendoderm development(GO:0048382)
0.0 0.4 GO:0032438 melanosome organization(GO:0032438)
0.0 0.1 GO:2000463 postsynaptic density assembly(GO:0097107) modulation of excitatory postsynaptic potential(GO:0098815) positive regulation of excitatory postsynaptic potential(GO:2000463)
0.0 0.3 GO:0048026 positive regulation of mRNA splicing, via spliceosome(GO:0048026)
0.0 0.2 GO:0036060 filtration diaphragm assembly(GO:0036058) slit diaphragm assembly(GO:0036060)
0.0 0.6 GO:0017121 phospholipid scrambling(GO:0017121)
0.0 1.2 GO:0050919 negative chemotaxis(GO:0050919)
0.0 0.7 GO:0030968 endoplasmic reticulum unfolded protein response(GO:0030968)
0.0 0.3 GO:0019934 cGMP-mediated signaling(GO:0019934)
0.0 0.6 GO:0006376 mRNA splice site selection(GO:0006376)
0.0 1.6 GO:0006672 ceramide metabolic process(GO:0006672)
0.0 0.5 GO:0051014 actin filament severing(GO:0051014)
0.0 0.4 GO:0008272 sulfate transport(GO:0008272)
0.0 0.1 GO:0045955 negative regulation of calcium ion-dependent exocytosis(GO:0045955) negative regulation of regulated secretory pathway(GO:1903306)
0.0 0.1 GO:0070257 regulation of mucus secretion(GO:0070255) positive regulation of mucus secretion(GO:0070257)
0.0 0.1 GO:0032228 regulation of synaptic transmission, GABAergic(GO:0032228)
0.0 0.4 GO:0007007 inner mitochondrial membrane organization(GO:0007007)
0.0 0.2 GO:0030214 hyaluronan catabolic process(GO:0030214)
0.0 2.0 GO:1990778 protein localization to plasma membrane(GO:0072659) protein localization to cell periphery(GO:1990778)
0.0 1.0 GO:0019216 regulation of lipid metabolic process(GO:0019216)
0.0 0.1 GO:1901021 activation of store-operated calcium channel activity(GO:0032237) positive regulation of calcium ion transmembrane transporter activity(GO:1901021) positive regulation of store-operated calcium channel activity(GO:1901341) positive regulation of calcium ion transmembrane transport(GO:1904427) positive regulation of cation channel activity(GO:2001259)
0.0 0.9 GO:0046839 phospholipid dephosphorylation(GO:0046839)
0.0 0.8 GO:0008217 regulation of blood pressure(GO:0008217)
0.0 0.4 GO:0042752 regulation of circadian rhythm(GO:0042752)
0.0 0.8 GO:1902476 chloride transmembrane transport(GO:1902476)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 4.0 GO:0098835 presynaptic endocytic zone(GO:0098833) presynaptic endocytic zone membrane(GO:0098835) extrinsic component of presynaptic membrane(GO:0098888) extrinsic component of presynaptic endocytic zone(GO:0098894)
0.2 1.7 GO:0032783 ELL-EAF complex(GO:0032783)
0.2 1.4 GO:0016012 sarcoglycan complex(GO:0016012)
0.2 4.7 GO:0043195 terminal bouton(GO:0043195)
0.2 2.2 GO:0042627 chylomicron(GO:0042627)
0.2 0.8 GO:0043034 costamere(GO:0043034)
0.1 1.5 GO:0044295 axonal growth cone(GO:0044295)
0.1 2.6 GO:0033017 sarcoplasmic reticulum membrane(GO:0033017)
0.1 5.8 GO:0032580 Golgi cisterna membrane(GO:0032580)
0.1 1.2 GO:0035098 ESC/E(Z) complex(GO:0035098)
0.1 1.7 GO:0005605 basal lamina(GO:0005605) laminin complex(GO:0043256)
0.1 1.9 GO:0000159 protein phosphatase type 2A complex(GO:0000159)
0.1 2.1 GO:0016605 PML body(GO:0016605)
0.1 1.1 GO:0070822 Sin3-type complex(GO:0070822)
0.0 0.4 GO:0061617 MICOS complex(GO:0061617)
0.0 0.8 GO:0031594 neuromuscular junction(GO:0031594)
0.0 0.5 GO:0008250 oligosaccharyltransferase complex(GO:0008250)
0.0 0.7 GO:0001917 photoreceptor inner segment(GO:0001917)
0.0 2.8 GO:0030141 secretory granule(GO:0030141)
0.0 0.7 GO:0033116 endoplasmic reticulum-Golgi intermediate compartment membrane(GO:0033116)
0.0 0.4 GO:0016363 nuclear matrix(GO:0016363)
0.0 1.0 GO:0005758 mitochondrial intermembrane space(GO:0005758) organelle envelope lumen(GO:0031970)
0.0 0.8 GO:1902711 GABA receptor complex(GO:1902710) GABA-A receptor complex(GO:1902711)
0.0 0.8 GO:0000421 autophagosome membrane(GO:0000421)
0.0 0.1 GO:0002189 ribose phosphate diphosphokinase complex(GO:0002189)
0.0 0.9 GO:0005795 Golgi stack(GO:0005795)
0.0 1.1 GO:0030427 site of polarized growth(GO:0030427)
0.0 3.9 GO:0048471 perinuclear region of cytoplasm(GO:0048471)
0.0 0.1 GO:0046695 SLIK (SAGA-like) complex(GO:0046695)
0.0 0.8 GO:0016342 catenin complex(GO:0016342)
0.0 3.3 GO:0045211 postsynaptic membrane(GO:0045211)
0.0 3.5 GO:0005938 cell cortex(GO:0005938)
0.0 0.6 GO:0031941 filamentous actin(GO:0031941)
0.0 0.4 GO:0042470 melanosome(GO:0042470) pigment granule(GO:0048770)
0.0 1.5 GO:0070160 bicellular tight junction(GO:0005923) occluding junction(GO:0070160)
0.0 0.5 GO:0005637 nuclear inner membrane(GO:0005637)
0.0 0.9 GO:0005882 intermediate filament(GO:0005882)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.7 2.2 GO:0034185 apolipoprotein binding(GO:0034185)
0.6 1.7 GO:0031701 angiotensin receptor binding(GO:0031701)
0.5 1.6 GO:0001729 ceramide kinase activity(GO:0001729)
0.5 3.2 GO:0050262 ribosylnicotinamide kinase activity(GO:0050262)
0.4 1.7 GO:0046556 alpha-L-arabinofuranosidase activity(GO:0046556)
0.4 1.6 GO:0005528 macrolide binding(GO:0005527) FK506 binding(GO:0005528)
0.4 1.6 GO:0015018 galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase activity(GO:0015018)
0.4 7.7 GO:0003785 actin monomer binding(GO:0003785)
0.3 7.7 GO:0031492 nucleosomal DNA binding(GO:0031492)
0.3 5.8 GO:0008417 fucosyltransferase activity(GO:0008417)
0.3 1.2 GO:0004464 leukotriene-C4 synthase activity(GO:0004464)
0.3 1.5 GO:0008046 axon guidance receptor activity(GO:0008046)
0.3 4.0 GO:0005545 1-phosphatidylinositol binding(GO:0005545)
0.3 0.8 GO:0005502 11-cis retinal binding(GO:0005502)
0.3 1.1 GO:0004657 proline dehydrogenase activity(GO:0004657)
0.2 2.6 GO:0004309 exopolyphosphatase activity(GO:0004309)
0.2 1.6 GO:0070888 E-box binding(GO:0070888)
0.2 1.4 GO:0008597 calcium-dependent protein serine/threonine phosphatase regulator activity(GO:0008597)
0.2 1.0 GO:0016531 copper chaperone activity(GO:0016531)
0.2 4.9 GO:0005112 Notch binding(GO:0005112)
0.2 1.3 GO:0030274 LIM domain binding(GO:0030274)
0.2 0.7 GO:1904121 phosphatidylethanolamine transporter activity(GO:1904121)
0.2 1.1 GO:0001642 group III metabotropic glutamate receptor activity(GO:0001642)
0.1 0.9 GO:0032217 riboflavin transporter activity(GO:0032217)
0.1 1.0 GO:0004128 cytochrome-b5 reductase activity, acting on NAD(P)H(GO:0004128)
0.1 0.5 GO:0004639 phosphoribosylaminoimidazolesuccinocarboxamide synthase activity(GO:0004639)
0.1 0.4 GO:0047804 cysteine-S-conjugate beta-lyase activity(GO:0047804)
0.1 0.8 GO:0098809 nitrite reductase activity(GO:0098809)
0.1 1.2 GO:0047676 arachidonate-CoA ligase activity(GO:0047676)
0.1 1.2 GO:0003886 DNA (cytosine-5-)-methyltransferase activity(GO:0003886)
0.1 3.5 GO:0005518 collagen binding(GO:0005518)
0.1 1.1 GO:0004029 aldehyde dehydrogenase (NAD) activity(GO:0004029)
0.1 1.2 GO:0035497 cAMP response element binding(GO:0035497)
0.1 0.8 GO:0051721 protein phosphatase 2A binding(GO:0051721)
0.1 0.6 GO:0017128 phospholipid scramblase activity(GO:0017128)
0.0 1.3 GO:0005246 calcium channel regulator activity(GO:0005246)
0.0 0.9 GO:0050811 GABA receptor binding(GO:0050811)
0.0 0.6 GO:0015187 glycine transmembrane transporter activity(GO:0015187)
0.0 0.2 GO:0033906 hyaluronoglucuronidase activity(GO:0033906)
0.0 0.6 GO:0038191 neuropilin binding(GO:0038191)
0.0 0.9 GO:0042577 lipid phosphatase activity(GO:0042577)
0.0 0.5 GO:0048495 Roundabout binding(GO:0048495)
0.0 1.2 GO:0035064 methylated histone binding(GO:0035064)
0.0 1.4 GO:0008020 G-protein coupled photoreceptor activity(GO:0008020)
0.0 0.9 GO:0098631 protein binding involved in cell adhesion(GO:0098631) protein binding involved in cell-cell adhesion(GO:0098632)
0.0 1.0 GO:0005109 frizzled binding(GO:0005109)
0.0 0.1 GO:0005093 Rab GDP-dissociation inhibitor activity(GO:0005093)
0.0 0.3 GO:0070915 lysophosphatidic acid receptor activity(GO:0070915)
0.0 0.8 GO:0004890 GABA-A receptor activity(GO:0004890)
0.0 0.1 GO:0004749 ribose phosphate diphosphokinase activity(GO:0004749)
0.0 1.1 GO:0005178 integrin binding(GO:0005178)
0.0 0.1 GO:0030160 GKAP/Homer scaffold activity(GO:0030160)
0.0 1.0 GO:0015020 glucuronosyltransferase activity(GO:0015020)
0.0 0.5 GO:0016628 oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor(GO:0016628)
0.0 0.4 GO:0008271 secondary active sulfate transmembrane transporter activity(GO:0008271)
0.0 2.7 GO:0005179 hormone activity(GO:0005179)
0.0 2.5 GO:0005262 calcium channel activity(GO:0005262)
0.0 0.1 GO:0015467 G-protein activated inward rectifier potassium channel activity(GO:0015467)
0.0 2.5 GO:0004222 metalloendopeptidase activity(GO:0004222)
0.0 15.9 GO:0005509 calcium ion binding(GO:0005509)
0.0 27.5 GO:0000978 RNA polymerase II core promoter proximal region sequence-specific DNA binding(GO:0000978)
0.0 0.8 GO:0030295 kinase activator activity(GO:0019209) protein kinase activator activity(GO:0030295)
0.0 1.0 GO:0019888 protein phosphatase regulator activity(GO:0019888)
0.0 1.8 GO:0005516 calmodulin binding(GO:0005516)
0.0 0.3 GO:0005388 calcium-transporting ATPase activity(GO:0005388)
0.0 2.6 GO:0030246 carbohydrate binding(GO:0030246)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.7 PID INTEGRIN4 PATHWAY Alpha6 beta4 integrin-ligand interactions
0.1 1.4 PID TCR CALCIUM PATHWAY Calcium signaling in the CD4+ TCR pathway
0.1 3.5 PID FRA PATHWAY Validated transcriptional targets of AP1 family members Fra1 and Fra2
0.1 1.7 PID INTEGRIN A9B1 PATHWAY Alpha9 beta1 integrin signaling events
0.0 5.4 PID P53 DOWNSTREAM PATHWAY Direct p53 effectors
0.0 1.4 PID MYC REPRESS PATHWAY Validated targets of C-MYC transcriptional repression
0.0 0.5 PID IL27 PATHWAY IL27-mediated signaling events
0.0 0.1 NABA BASEMENT MEMBRANES Genes encoding structural components of basement membranes
0.0 1.6 PID REG GR PATHWAY Glucocorticoid receptor regulatory network
0.0 1.1 PID CASPASE PATHWAY Caspase cascade in apoptosis
0.0 0.8 PID AJDISS 2PATHWAY Posttranslational regulation of adherens junction stability and dissassembly
0.0 0.7 PID PTP1B PATHWAY Signaling events mediated by PTP1B
0.0 1.6 PID BETA CATENIN NUC PATHWAY Regulation of nuclear beta catenin signaling and target gene transcription
0.0 0.7 PID INTEGRIN1 PATHWAY Beta1 integrin cell surface interactions
0.0 0.8 PID RHOA REG PATHWAY Regulation of RhoA activity
0.0 2.5 NABA ECM GLYCOPROTEINS Genes encoding structural ECM glycoproteins

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 3.0 REACTOME CHYLOMICRON MEDIATED LIPID TRANSPORT Genes involved in Chylomicron-mediated lipid transport
0.3 3.7 REACTOME CS DS DEGRADATION Genes involved in CS/DS degradation
0.2 0.8 REACTOME PD1 SIGNALING Genes involved in PD-1 signaling
0.2 2.0 REACTOME REGULATION OF PYRUVATE DEHYDROGENASE PDH COMPLEX Genes involved in Regulation of pyruvate dehydrogenase (PDH) complex
0.1 2.8 REACTOME REGULATION OF GENE EXPRESSION IN BETA CELLS Genes involved in Regulation of gene expression in beta cells
0.1 0.8 REACTOME OPSINS Genes involved in Opsins
0.1 0.7 REACTOME DCC MEDIATED ATTRACTIVE SIGNALING Genes involved in DCC mediated attractive signaling
0.1 1.7 REACTOME P130CAS LINKAGE TO MAPK SIGNALING FOR INTEGRINS Genes involved in p130Cas linkage to MAPK signaling for integrins
0.1 0.7 REACTOME SPRY REGULATION OF FGF SIGNALING Genes involved in Spry regulation of FGF signaling
0.1 0.5 REACTOME IL 6 SIGNALING Genes involved in Interleukin-6 signaling
0.1 3.3 REACTOME RESPONSE TO ELEVATED PLATELET CYTOSOLIC CA2 Genes involved in Response to elevated platelet cytosolic Ca2+
0.0 1.9 REACTOME NUCLEAR RECEPTOR TRANSCRIPTION PATHWAY Genes involved in Nuclear Receptor transcription pathway
0.0 0.6 REACTOME NA CL DEPENDENT NEUROTRANSMITTER TRANSPORTERS Genes involved in Na+/Cl- dependent neurotransmitter transporters
0.0 1.7 REACTOME INTEGRIN CELL SURFACE INTERACTIONS Genes involved in Integrin cell surface interactions
0.0 0.1 REACTOME BETA DEFENSINS Genes involved in Beta defensins
0.0 0.1 REACTOME SIGNAL REGULATORY PROTEIN SIRP FAMILY INTERACTIONS Genes involved in Signal regulatory protein (SIRP) family interactions
0.0 1.5 REACTOME GOLGI ASSOCIATED VESICLE BIOGENESIS Genes involved in Golgi Associated Vesicle Biogenesis
0.0 0.4 REACTOME BILE SALT AND ORGANIC ANION SLC TRANSPORTERS Genes involved in Bile salt and organic anion SLC transporters
0.0 1.0 REACTOME CROSS PRESENTATION OF SOLUBLE EXOGENOUS ANTIGENS ENDOSOMES Genes involved in Cross-presentation of soluble exogenous antigens (endosomes)
0.0 0.7 REACTOME SIGNALING BY ROBO RECEPTOR Genes involved in Signaling by Robo receptor
0.0 0.5 REACTOME CHOLESTEROL BIOSYNTHESIS Genes involved in Cholesterol biosynthesis
0.0 0.8 REACTOME NRAGE SIGNALS DEATH THROUGH JNK Genes involved in NRAGE signals death through JNK
0.0 0.7 REACTOME VOLTAGE GATED POTASSIUM CHANNELS Genes involved in Voltage gated Potassium channels
0.0 0.3 REACTOME CGMP EFFECTS Genes involved in cGMP effects
0.0 0.4 REACTOME CYTOCHROME P450 ARRANGED BY SUBSTRATE TYPE Genes involved in Cytochrome P450 - arranged by substrate type
0.0 0.6 REACTOME O LINKED GLYCOSYLATION OF MUCINS Genes involved in O-linked glycosylation of mucins