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PRJNA195909:zebrafish embryo and larva development
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Results for pou2f3
Z-value: 1.37
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Transcription factors associated with pou2f3
Activity-expression correlation:
| Gene | Promoter | Pearson corr. coef. | P-value | Plot |
|---|---|---|---|---|
| pou2f3 | dr11_v1_chr5_+_58550795_58550795 | -0.40 | 2.9e-01 | Click! |
| Promoter | Log-likelihood | Transcript | Gene | Gene Info |
|---|---|---|---|---|
| chr11_+_30647545 Show fit | 2.61 |
ENSDART00000114792
|
expressed sequence EH507706 |
|
| chr7_+_13582256 Show fit | 1.99 |
ENSDART00000158477
|
ankyrin repeat and death domain containing 1A |
|
| chr14_+_15155684 Show fit | 1.97 |
ENSDART00000167966
|
zgc:158852 |
|
| chr17_+_12075805 Show fit | 1.59 |
ENSDART00000155329
|
consortin, connexin sorting protein a |
|
| chr21_+_36623162 Show fit | 1.58 |
ENSDART00000027459
|
G protein-coupled receptor kinase 6 |
|
| chr12_+_46543572 Show fit | 1.49 |
ENSDART00000167510
|
HID1 domain containing b |
|
| chr17_-_6641535 Show fit | 1.42 |
ENSDART00000154540
ENSDART00000180384 |
si:ch211-189e2.3 |
|
| chr3_-_59981162 Show fit | 1.42 |
ENSDART00000128790
|
cerebellar degeneration-related protein 2-like |
|
| chr10_+_34001444 Show fit | 1.40 |
ENSDART00000149934
|
klotho |
|
| chr11_+_13176568 Show fit | 1.37 |
ENSDART00000125371
ENSDART00000123257 |
MAP kinase interacting serine/threonine kinase 1 |
Network of associatons between targets according to the STRING database.
First level regulatory network of pou2f3
Gene Ontology Analysis
Gene overrepresentation in biological process category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.5 | 2.2 | GO:0046166 | methylglyoxal biosynthetic process(GO:0019242) glyceraldehyde-3-phosphate biosynthetic process(GO:0046166) |
| 0.0 | 2.2 | GO:0046856 | phosphatidylinositol dephosphorylation(GO:0046856) |
| 0.0 | 2.1 | GO:0007030 | Golgi organization(GO:0007030) |
| 0.3 | 1.8 | GO:0042795 | snRNA transcription from RNA polymerase II promoter(GO:0042795) |
| 0.5 | 1.6 | GO:0042998 | positive regulation of Golgi to plasma membrane protein transport(GO:0042998) positive regulation of establishment of protein localization to plasma membrane(GO:0090004) |
| 0.2 | 1.5 | GO:0060282 | positive regulation of oocyte development(GO:0060282) |
| 0.2 | 1.5 | GO:0070498 | interleukin-1-mediated signaling pathway(GO:0070498) |
| 0.1 | 1.5 | GO:0043124 | negative regulation of I-kappaB kinase/NF-kappaB signaling(GO:0043124) |
| 0.0 | 1.5 | GO:0046854 | phosphatidylinositol phosphorylation(GO:0046854) |
| 0.0 | 1.4 | GO:0008286 | insulin receptor signaling pathway(GO:0008286) |
Gene overrepresentation in cellular component category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 1.8 | GO:0008023 | transcription elongation factor complex(GO:0008023) |
| 0.0 | 1.8 | GO:0005793 | endoplasmic reticulum-Golgi intermediate compartment(GO:0005793) |
| 0.3 | 1.5 | GO:0005797 | Golgi medial cisterna(GO:0005797) |
| 0.1 | 1.5 | GO:0071144 | SMAD2-SMAD3 protein complex(GO:0071144) |
| 0.1 | 1.4 | GO:0036449 | microtubule minus-end(GO:0036449) |
| 0.1 | 1.3 | GO:0002102 | podosome(GO:0002102) |
| 0.0 | 1.2 | GO:0055038 | recycling endosome membrane(GO:0055038) |
| 0.0 | 1.0 | GO:0005921 | gap junction(GO:0005921) |
| 0.0 | 1.0 | GO:0010494 | cytoplasmic stress granule(GO:0010494) |
| 0.0 | 1.0 | GO:0005844 | polysome(GO:0005844) |
Gene overrepresentation in molecular function category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.5 | 2.2 | GO:0008929 | triose-phosphate isomerase activity(GO:0004807) methylglyoxal synthase activity(GO:0008929) |
| 0.0 | 1.9 | GO:0004715 | non-membrane spanning protein tyrosine kinase activity(GO:0004715) |
| 0.2 | 1.7 | GO:0052629 | phosphatidylinositol-3,5-bisphosphate 3-phosphatase activity(GO:0052629) |
| 0.4 | 1.6 | GO:0071253 | connexin binding(GO:0071253) |
| 0.1 | 1.6 | GO:0004703 | G-protein coupled receptor kinase activity(GO:0004703) |
| 0.1 | 1.5 | GO:0070411 | I-SMAD binding(GO:0070411) |
| 0.1 | 1.4 | GO:0008422 | beta-glucosidase activity(GO:0008422) |
| 0.1 | 1.4 | GO:0051011 | microtubule minus-end binding(GO:0051011) |
| 0.0 | 1.4 | GO:0009931 | calcium-dependent protein serine/threonine kinase activity(GO:0009931) |
| 0.0 | 1.3 | GO:0030165 | PDZ domain binding(GO:0030165) |
Gene overrepresentation in curated gene sets: canonical pathways category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 3.3 | PID CXCR4 PATHWAY | CXCR4-mediated signaling events |
| 0.1 | 1.9 | PID TOLL ENDOGENOUS PATHWAY | Endogenous TLR signaling |
| 0.1 | 1.5 | PID SMAD2 3PATHWAY | Regulation of cytoplasmic and nuclear SMAD2/3 signaling |
| 0.0 | 1.4 | PID P38 ALPHA BETA DOWNSTREAM PATHWAY | Signaling mediated by p38-alpha and p38-beta |
| 0.0 | 1.0 | PID AR TF PATHWAY | Regulation of Androgen receptor activity |
| 0.0 | 0.8 | PID FRA PATHWAY | Validated transcriptional targets of AP1 family members Fra1 and Fra2 |
| 0.0 | 0.7 | SA PTEN PATHWAY | PTEN is a tumor suppressor that dephosphorylates the lipid messenger phosphatidylinositol triphosphate. |
| 0.0 | 0.7 | PID MAPK TRK PATHWAY | Trk receptor signaling mediated by the MAPK pathway |
| 0.0 | 0.6 | PID PI3KCI AKT PATHWAY | Class I PI3K signaling events mediated by Akt |
| 0.0 | 0.6 | PID CDC42 PATHWAY | CDC42 signaling events |
Gene overrepresentation in curated gene sets: REACTOME pathways category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.1 | 2.1 | REACTOME ELONGATION ARREST AND RECOVERY | Genes involved in Elongation arrest and recovery |
| 0.2 | 1.8 | REACTOME SIGNALING BY NODAL | Genes involved in Signaling by NODAL |
| 0.0 | 1.6 | REACTOME MHC CLASS II ANTIGEN PRESENTATION | Genes involved in MHC class II antigen presentation |
| 0.3 | 1.5 | REACTOME PD1 SIGNALING | Genes involved in PD-1 signaling |
| 0.1 | 1.5 | REACTOME TRAF6 MEDIATED IRF7 ACTIVATION IN TLR7 8 OR 9 SIGNALING | Genes involved in TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling |
| 0.1 | 1.5 | REACTOME NEGATIVE REGULATORS OF RIG I MDA5 SIGNALING | Genes involved in Negative regulators of RIG-I/MDA5 signaling |
| 0.1 | 1.4 | REACTOME FGFR LIGAND BINDING AND ACTIVATION | Genes involved in FGFR ligand binding and activation |
| 0.0 | 1.2 | REACTOME ASSOCIATION OF TRIC CCT WITH TARGET PROTEINS DURING BIOSYNTHESIS | Genes involved in Association of TriC/CCT with target proteins during biosynthesis |
| 0.1 | 0.9 | REACTOME SYNTHESIS OF PE | Genes involved in Synthesis of PE |
| 0.0 | 0.9 | REACTOME CHOLESTEROL BIOSYNTHESIS | Genes involved in Cholesterol biosynthesis |