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PRJNA195909:zebrafish embryo and larva development
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Results for pou2f2a
Z-value: 1.61
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Transcription factors associated with pou2f2a
Activity-expression correlation:
| Gene | Promoter | Pearson corr. coef. | P-value | Plot |
|---|---|---|---|---|
| pou2f2a | dr11_v1_chr19_-_6239248_6239248 | -0.38 | 3.1e-01 | Click! |
| Promoter | Log-likelihood | Transcript | Gene | Gene Info |
|---|---|---|---|---|
| chr13_-_6081803 Show fit | 2.95 |
ENSDART00000099224
|
deltaD |
|
| chr14_-_32965169 Show fit | 2.43 |
ENSDART00000114973
|
caudal type homeobox 4 |
|
| chr11_-_11575070 Show fit | 2.29 |
ENSDART00000142208
|
zgc:110712 |
|
| chr17_+_26965351 Show fit | 1.72 |
ENSDART00000114215
ENSDART00000147192 |
grainyhead-like transcription factor 3 |
|
| chr23_+_23232136 Show fit | 1.55 |
ENSDART00000126479
ENSDART00000187764 |
pleckstrin homology domain containing, family N member 1 |
|
| chr23_-_31372639 Show fit | 1.54 |
ENSDART00000179908
ENSDART00000135620 ENSDART00000053367 |
high mobility group nucleosomal binding domain 3 |
|
| chr1_-_46832880 Show fit | 1.44 |
ENSDART00000142406
|
si:ch73-160h15.3 |
|
| chr9_-_53666031 Show fit | 1.40 |
ENSDART00000126314
|
protocadherin 8 |
|
| chr1_+_51039558 Show fit | 1.39 |
ENSDART00000024743
|
dpy-30 histone methyltransferase complex regulatory subunit |
|
| chr19_-_340641 Show fit | 1.37 |
ENSDART00000183848
|
golgi phosphoprotein 3-like |
Network of associatons between targets according to the STRING database.
First level regulatory network of pou2f2a
Gene Ontology Analysis
Gene overrepresentation in biological process category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.6 | 3.0 | GO:0021523 | somatic motor neuron differentiation(GO:0021523) |
| 0.2 | 2.6 | GO:0060325 | face morphogenesis(GO:0060325) |
| 0.1 | 2.6 | GO:0030199 | collagen fibril organization(GO:0030199) |
| 0.2 | 2.5 | GO:0014036 | neural crest cell fate commitment(GO:0014034) neural crest cell fate specification(GO:0014036) |
| 0.5 | 2.4 | GO:0003311 | pancreatic D cell differentiation(GO:0003311) foregut morphogenesis(GO:0007440) |
| 0.2 | 2.3 | GO:0048339 | paraxial mesoderm development(GO:0048339) |
| 0.3 | 2.0 | GO:0021767 | mammillary body development(GO:0021767) |
| 0.2 | 2.0 | GO:0002043 | blood vessel endothelial cell proliferation involved in sprouting angiogenesis(GO:0002043) |
| 0.1 | 1.9 | GO:0031641 | regulation of myelination(GO:0031641) |
| 0.2 | 1.8 | GO:0006189 | 'de novo' IMP biosynthetic process(GO:0006189) |
Gene overrepresentation in cellular component category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 3.4 | GO:0048471 | perinuclear region of cytoplasm(GO:0048471) |
| 0.6 | 1.9 | GO:0043220 | compact myelin(GO:0043218) Schmidt-Lanterman incisure(GO:0043220) |
| 0.4 | 1.7 | GO:0005880 | nuclear microtubule(GO:0005880) |
| 0.0 | 1.7 | GO:0032580 | Golgi cisterna membrane(GO:0032580) |
| 0.0 | 1.5 | GO:0030141 | secretory granule(GO:0030141) |
| 0.0 | 1.4 | GO:0016342 | catenin complex(GO:0016342) |
| 0.1 | 1.3 | GO:0048188 | Set1C/COMPASS complex(GO:0048188) |
| 0.3 | 1.1 | GO:0016600 | flotillin complex(GO:0016600) |
| 0.0 | 0.8 | GO:0032156 | septin ring(GO:0005940) septin complex(GO:0031105) septin cytoskeleton(GO:0032156) |
| 0.0 | 0.7 | GO:0005811 | lipid particle(GO:0005811) |
Gene overrepresentation in molecular function category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 35.6 | GO:0000981 | RNA polymerase II transcription factor activity, sequence-specific DNA binding(GO:0000981) |
| 0.1 | 3.5 | GO:0005112 | Notch binding(GO:0005112) |
| 0.1 | 2.3 | GO:0005518 | collagen binding(GO:0005518) |
| 0.1 | 1.9 | GO:0019911 | structural constituent of myelin sheath(GO:0019911) |
| 0.5 | 1.6 | GO:1901612 | cardiolipin binding(GO:1901612) |
| 0.1 | 1.5 | GO:0031492 | nucleosomal DNA binding(GO:0031492) |
| 0.0 | 1.5 | GO:0005109 | frizzled binding(GO:0005109) |
| 0.3 | 1.4 | GO:0050211 | procollagen galactosyltransferase activity(GO:0050211) |
| 0.1 | 1.4 | GO:0070273 | phosphatidylinositol-4-phosphate binding(GO:0070273) |
| 0.4 | 1.3 | GO:0016713 | cholesterol monooxygenase (side-chain-cleaving) activity(GO:0008386) oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced iron-sulfur protein as one donor, and incorporation of one atom of oxygen(GO:0016713) |
Gene overrepresentation in curated gene sets: canonical pathways category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 3.5 | PID BETA CATENIN NUC PATHWAY | Regulation of nuclear beta catenin signaling and target gene transcription |
| 0.1 | 3.0 | ST JNK MAPK PATHWAY | JNK MAPK Pathway |
| 0.0 | 1.5 | PID NOTCH PATHWAY | Notch signaling pathway |
| 0.0 | 1.4 | PID TAP63 PATHWAY | Validated transcriptional targets of TAp63 isoforms |
| 0.0 | 1.2 | PID CASPASE PATHWAY | Caspase cascade in apoptosis |
| 0.0 | 0.4 | ST GA12 PATHWAY | G alpha 12 Pathway |
| 0.0 | 0.4 | SIG REGULATION OF THE ACTIN CYTOSKELETON BY RHO GTPASES | Genes related to regulation of the actin cytoskeleton |
| 0.0 | 0.4 | PID IL2 STAT5 PATHWAY | IL2 signaling events mediated by STAT5 |
| 0.0 | 0.3 | PID GLYPICAN 1PATHWAY | Glypican 1 network |
| 0.0 | 0.3 | PID WNT SIGNALING PATHWAY | Wnt signaling network |
Gene overrepresentation in curated gene sets: REACTOME pathways category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.2 | 3.0 | REACTOME REGULATION OF PYRUVATE DEHYDROGENASE PDH COMPLEX | Genes involved in Regulation of pyruvate dehydrogenase (PDH) complex |
| 0.1 | 1.8 | REACTOME PURINE RIBONUCLEOSIDE MONOPHOSPHATE BIOSYNTHESIS | Genes involved in Purine ribonucleoside monophosphate biosynthesis |
| 0.1 | 1.5 | REACTOME ACTIVATED NOTCH1 TRANSMITS SIGNAL TO THE NUCLEUS | Genes involved in Activated NOTCH1 Transmits Signal to the Nucleus |
| 0.1 | 1.3 | REACTOME ENDOGENOUS STEROLS | Genes involved in Endogenous sterols |
| 0.1 | 0.6 | REACTOME CHYLOMICRON MEDIATED LIPID TRANSPORT | Genes involved in Chylomicron-mediated lipid transport |
| 0.0 | 0.5 | REACTOME MITOCHONDRIAL PROTEIN IMPORT | Genes involved in Mitochondrial Protein Import |
| 0.0 | 0.4 | REACTOME SIGNALING BY NODAL | Genes involved in Signaling by NODAL |
| 0.0 | 0.4 | REACTOME SYNTHESIS OF PIPS AT THE GOLGI MEMBRANE | Genes involved in Synthesis of PIPs at the Golgi membrane |
| 0.0 | 0.4 | REACTOME SPHINGOLIPID DE NOVO BIOSYNTHESIS | Genes involved in Sphingolipid de novo biosynthesis |
| 0.0 | 0.4 | REACTOME EFFECTS OF PIP2 HYDROLYSIS | Genes involved in Effects of PIP2 hydrolysis |