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PRJNA195909:zebrafish embryo and larva development

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Results for pou2f1b

Z-value: 0.76

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Transcription factors associated with pou2f1b

Gene Symbol Gene ID Gene Info
ENSDARG00000007996 POU class 2 homeobox 1b

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
pou2f1bdr11_v1_chr9_+_34331368_343313680.511.6e-01Click!

Activity profile of pou2f1b motif

Sorted Z-values of pou2f1b motif

Promoter Log-likelihood Transcript Gene Gene Info
chr17_-_6618574 2.53 ENSDART00000184486
si:ch211-189e2.3
chr20_-_41992878 2.04 ENSDART00000100967
si:dkeyp-114g9.1
chr21_+_1119046 1.74 ENSDART00000184678

chr17_-_6641535 1.53 ENSDART00000154540
ENSDART00000180384
si:ch211-189e2.3
chr19_+_2835240 1.33 ENSDART00000190838
CUB domain containing protein 1
chr19_-_27570333 1.22 ENSDART00000146562
ENSDART00000179060
si:dkeyp-46h3.5
si:dkeyp-46h3.8
chr15_+_38308421 1.16 ENSDART00000129941
si:dkey-24p1.6
chr12_+_22560067 1.12 ENSDART00000172066
polymerase (RNA) II (DNA directed) polypeptide A
chr22_+_14836040 1.08 ENSDART00000180951
GTP binding protein 1, like
chr14_-_46198373 1.04 ENSDART00000031640
ENSDART00000132966
zgc:113425
chr2_+_37430917 1.03 ENSDART00000140558
polyhomeotic homolog 3 (Drosophila)
chr1_-_55262763 1.00 ENSDART00000152769
si:ch211-286b5.4
chr5_-_11809710 0.91 ENSDART00000186998
ENSDART00000181363
ENSDART00000180681
neurofibromin 2a (merlin)
chr6_+_28208973 0.90 ENSDART00000171216
ENSDART00000171377
ENSDART00000167389
ENSDART00000166988
si:ch73-14h10.2
chr24_-_21150100 0.89 ENSDART00000154249
ENSDART00000193256
GRAM domain containing 1c
chr13_+_33462232 0.86 ENSDART00000177841
zgc:136302
chr14_-_45967981 0.85 ENSDART00000188062
MACRO domain containing 1
chr20_-_49889111 0.85 ENSDART00000058858
kinesin family member 13Bb
chr19_-_27550768 0.83 ENSDART00000142313
si:dkeyp-46h3.8
chr15_-_18209672 0.81 ENSDART00000141508
ENSDART00000136280
bloodthirsty-related gene family, member 16
chr16_+_50434668 0.79 ENSDART00000193500
zgc:110372
chr17_-_25831569 0.73 ENSDART00000148743
hedgehog acyltransferase
chr18_+_3579829 0.73 ENSDART00000158763
ENSDART00000182850
ENSDART00000162754
ENSDART00000178789
ENSDART00000172656
leucine-rich repeats and calponin homology (CH) domain containing 3
chr23_+_12160900 0.72 ENSDART00000136046
protein phosphatase 1, regulatory subunit 3Da
chr22_+_24318131 0.72 ENSDART00000187360
ENSDART00000165618
coiled-coil domain containing 50
chr5_-_68779747 0.72 ENSDART00000192636
ENSDART00000188039
methylphosphate capping enzyme
chr10_+_34001444 0.71 ENSDART00000149934
klotho
chr7_+_19600262 0.71 ENSDART00000007310
zgc:171731
chr8_-_44238526 0.68 ENSDART00000061115
ENSDART00000132473
ENSDART00000138019
ENSDART00000133021
piwi-like RNA-mediated gene silencing 1
chr12_-_35582683 0.67 ENSDART00000167933
SEC24 homolog C, COPII coat complex component
chr14_-_7409364 0.67 ENSDART00000036463
DND microRNA-mediated repression inhibitor 1
chr22_+_14836291 0.65 ENSDART00000122740
GTP binding protein 1, like
chr12_-_22238004 0.65 ENSDART00000038310
ORMDL sphingolipid biosynthesis regulator 3
chr15_+_5132439 0.64 ENSDART00000010350
phosphoglucomutase 2-like 1
chr2_+_6253246 0.64 ENSDART00000058256
ENSDART00000076700
zona pellucida glycoprotein 3b
chr18_+_8917766 0.63 ENSDART00000145226
si:ch211-233h19.2
chr15_+_29393519 0.62 ENSDART00000193488
ENSDART00000112375
glycerophosphodiester phosphodiesterase domain containing 5b
chr14_-_45967712 0.61 ENSDART00000043751
ENSDART00000141357
MACRO domain containing 1
chr19_+_1510971 0.61 ENSDART00000157721
solute carrier family 45 member 4
chr19_+_1688727 0.61 ENSDART00000115136
ENSDART00000166744
DENN/MADD domain containing 3a
chr6_+_33931095 0.60 ENSDART00000191909
origin recognition complex, subunit 1
chr3_-_36153591 0.60 ENSDART00000190515
endo-beta-N-acetylglucosaminidase
chr16_-_42770064 0.59 ENSDART00000112879
solute carrier family 4, sodium bicarbonate cotransporter, member 7
chr24_-_12770357 0.59 ENSDART00000060826
importin 4
chr10_-_244745 0.59 ENSDART00000136551
kelch-like family member 35
chr18_+_22287084 0.59 ENSDART00000151919
ENSDART00000181644
CCCTC-binding factor (zinc finger protein)
chr5_-_13206878 0.58 ENSDART00000051666
protein phosphatase, Mg2+/Mn2+ dependent, 1F
chr8_-_39884359 0.57 ENSDART00000131372
malectin
chr2_-_21438492 0.57 ENSDART00000046098
phospholipase C, delta 1b
chr22_-_37834312 0.56 ENSDART00000076128
protein phosphatase 1, regulatory (inhibitor) subunit 2
chr4_-_72643171 0.55 ENSDART00000130126

chr24_+_39586701 0.54 ENSDART00000136447
si:dkey-161j23.7
chr10_-_41157135 0.54 ENSDART00000134851
AP2 associated kinase 1b
chr5_-_65662996 0.54 ENSDART00000147707
calmodulin regulated spectrin-associated protein 1b
chr9_-_8297344 0.54 ENSDART00000180945
si:ch211-145c1.1
chr16_+_53590586 0.53 ENSDART00000083534
G patch domain containing 3
chr24_+_7322116 0.53 ENSDART00000005804
X-ray repair cross complementing 2
chr23_+_27789795 0.53 ENSDART00000141458
lysine (K)-specific methyltransferase 2D
chr11_+_30647545 0.53 ENSDART00000114792
expressed sequence EH507706
chr21_-_39546737 0.53 ENSDART00000006971
septin 4a
chr14_-_16754262 0.52 ENSDART00000001159
mannosyl (alpha-1,3-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase, isozyme B
chr6_+_54687495 0.52 ENSDART00000189514
sphingomyelin phosphodiesterase 2b, neutral membrane (neutral sphingomyelinase)
chr8_+_41038141 0.51 ENSDART00000075620
glycerol-3-phosphate acyltransferase 2, mitochondrial
chr25_-_9013963 0.51 ENSDART00000073912
recombination activating gene 2
chr9_-_30502010 0.51 ENSDART00000149483
si:dkey-229b18.3
chr21_-_3613702 0.51 ENSDART00000139194
dymeclin
chr2_-_9915814 0.50 ENSDART00000091644
ENSDART00000177556
abl-interactor 1b
chr15_-_30815826 0.49 ENSDART00000156160
ENSDART00000145918
musashi RNA-binding protein 2b
chr5_-_1487256 0.49 ENSDART00000149599
ENSDART00000148411
ENSDART00000092087
ENSDART00000148464
golgin A2
chr21_+_45502621 0.49 ENSDART00000166719
si:dkey-223p19.2
chr3_+_7771420 0.49 ENSDART00000156809
ENSDART00000156309
hook microtubule-tethering protein 2
chr4_+_6869847 0.48 ENSDART00000036646
dedicator of cytokinesis 4b
chr6_-_17999776 0.48 ENSDART00000183048
ENSDART00000181577
ENSDART00000170597
regulatory associated protein of MTOR, complex 1
chr17_+_28628404 0.48 ENSDART00000032975
ENSDART00000143607
HEAT repeat containing 5a
chr10_+_23060391 0.48 ENSDART00000079711
solute carrier family 25 (mitochondrial carrier; citrate transporter), member 1a
chr23_+_44665230 0.48 ENSDART00000144958
calmodulin binding transcription activator 2
chr21_+_76739 0.48 ENSDART00000174654
arylsulfatase B
chr1_-_51038885 0.48 ENSDART00000035150
spastin
chr16_-_43011470 0.47 ENSDART00000131898
ENSDART00000142003
ENSDART00000017966
nudix (nucleoside diphosphate linked moiety X)-type motif 17
chr25_+_27937585 0.47 ENSDART00000151994
Ca++-dependent secretion activator 2
chr11_-_21404044 0.47 ENSDART00000080116
inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon
chr3_-_59981476 0.47 ENSDART00000035878
ENSDART00000124038
cerebellar degeneration-related protein 2-like
chr20_+_4221978 0.47 ENSDART00000171898
interaction protein for cytohesin exchange factors 1
chr9_-_12659140 0.47 ENSDART00000058565
PTTG1 interacting protein b
chr21_-_43398457 0.47 ENSDART00000166530
cyclin I family, member 2
chr21_-_34926619 0.46 ENSDART00000065337
ENSDART00000192740
kinesin family member 20A
chr25_+_27937789 0.46 ENSDART00000023890
Ca++-dependent secretion activator 2
chr25_+_22320738 0.45 ENSDART00000073566
cytochrome P450, family 11, subfamily A, polypeptide 1
chr9_+_48755638 0.45 ENSDART00000047401
ATP-binding cassette, sub-family B (MDR/TAP), member 11a
chr22_+_14051894 0.44 ENSDART00000142548
aldehyde oxidase 6
chr19_-_977849 0.44 ENSDART00000172303

chr19_+_43684376 0.44 ENSDART00000051723
si:ch211-193k19.1
chr17_+_20576848 0.44 ENSDART00000183203
zgc:162183
chr17_+_1544903 0.44 ENSDART00000156244
ENSDART00000112183
centrosomal protein 170B
chr8_+_41037541 0.44 ENSDART00000129344
glycerol-3-phosphate acyltransferase 2, mitochondrial
chr7_-_72155022 0.44 ENSDART00000187984
zmp:0000001168
chr5_-_8711157 0.44 ENSDART00000062957
poly(A) binding protein interacting protein 1
chr6_-_16394528 0.44 ENSDART00000089445
ArfGAP with GTPase domain, ankyrin repeat and PH domain 1
chr4_-_3353595 0.44 ENSDART00000009076
phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit gamma
chr18_-_15551360 0.44 ENSDART00000159915
ENSDART00000172690
PTPRF interacting protein, binding protein 1b (liprin beta 1)
chr20_-_34754617 0.43 ENSDART00000148066
zinc finger protein 395b
chr15_-_14038227 0.43 ENSDART00000139068
zgc:114130
chr2_-_21625493 0.43 ENSDART00000137169
zgc:55781
chr10_+_29771256 0.43 ENSDART00000193195
hypoxia up-regulated 1
chr7_+_13582256 0.42 ENSDART00000158477
ankyrin repeat and death domain containing 1A
chr20_-_18794789 0.42 ENSDART00000003834
cerebral cavernous malformation 2
chr11_-_26576754 0.42 ENSDART00000191733
ENSDART00000002846
ST3 beta-galactoside alpha-2,3-sialyltransferase 8
chr25_+_34862225 0.41 ENSDART00000149782
zgc:194879
chr9_+_17983463 0.41 ENSDART00000182150
A kinase (PRKA) anchor protein 11
chr7_-_19364813 0.41 ENSDART00000173977
netrin 4
chr11_-_38083397 0.41 ENSDART00000086516
ENSDART00000184033
kelch domain containing 8A
chr12_-_4243268 0.40 ENSDART00000131275
zgc:92313
chr7_-_26497947 0.40 ENSDART00000058910
SRY (sex determining region Y)-box 19b
chr18_-_26715655 0.40 ENSDART00000181497
MALT paracaspase 3
chr11_-_21404358 0.40 ENSDART00000129062
inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon
chr24_-_41180149 0.40 ENSDART00000019975
activin A receptor type 2Ba
chr13_-_43637371 0.40 ENSDART00000127930
ENSDART00000084474
family with sequence similarity 160, member B1
chr7_-_45852270 0.40 ENSDART00000170224
SHC SH2-domain binding protein 1
chr12_-_35582521 0.40 ENSDART00000162175
ENSDART00000168958
SEC24 homolog C, COPII coat complex component
chr11_+_5817202 0.40 ENSDART00000126084
CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase like 3
chr20_-_9123052 0.40 ENSDART00000125133
Myb-like, SWIRM and MPN domains 1
chr11_-_18791834 0.40 ENSDART00000156431
6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 2b
chr14_+_16083818 0.39 ENSDART00000168462
ring finger protein 103
chr24_+_39135419 0.39 ENSDART00000180941
TBC1 domain family, member 24
chr12_-_6551681 0.38 ENSDART00000145413
si:ch211-253p2.2
chr17_+_28102487 0.38 ENSDART00000131638
ENSDART00000076265
zgc:91908
chr8_-_47329755 0.38 ENSDART00000060853
peroxisomal biogenesis factor 10
chr3_-_21106093 0.38 ENSDART00000156566
MYC-associated zinc finger protein a (purine-binding transcription factor)
chr13_+_11550454 0.38 ENSDART00000034935
ENSDART00000166908
desumoylating isopeptidase 2
chr2_+_44615000 0.38 ENSDART00000188826
ENSDART00000113232
YEATS domain containing 2
chr13_-_23756700 0.38 ENSDART00000057612
regulator of G protein signaling 17
chr21_-_11054605 0.38 ENSDART00000191378
ENSDART00000084061
neural precursor cell expressed, developmentally down-regulated 4-like
chr23_-_33775145 0.37 ENSDART00000132147
ENSDART00000027959
ENSDART00000160116
Rac GTPase activating protein 1
chr20_-_9123296 0.37 ENSDART00000188495
Myb-like, SWIRM and MPN domains 1
chr18_-_26715156 0.37 ENSDART00000142043
MALT paracaspase 3
chr19_+_15485287 0.37 ENSDART00000182797
PDLIM1 interacting kinase 1 like
chr9_-_12443726 0.37 ENSDART00000102434
enoyl-CoA, hydratase/3-hydroxyacyl CoA dehydrogenase
chr14_-_4044545 0.37 ENSDART00000169527
sorting nexin 25
chr6_+_30491129 0.37 ENSDART00000088142
WWC family member 3
chr23_-_36857964 0.37 ENSDART00000188822
ENSDART00000134061
ENSDART00000093061
homeodomain interacting protein kinase 1a
chr10_+_31809226 0.37 ENSDART00000087898
forkhead box O1 b
chr21_+_36623162 0.37 ENSDART00000027459
G protein-coupled receptor kinase 6
chr21_+_45502773 0.36 ENSDART00000160059
ENSDART00000165704
si:dkey-223p19.2
chr1_+_19434198 0.36 ENSDART00000012552
clock circadian regulator b
chr24_-_20641000 0.36 ENSDART00000166135
zinc finger and BTB domain containing 47b
chr10_+_399363 0.36 ENSDART00000147449
si:ch211-242f23.8
chr16_+_52847079 0.36 ENSDART00000163151
centrosomal protein 72
chr3_-_59981162 0.36 ENSDART00000128790
cerebellar degeneration-related protein 2-like
chr20_-_14941046 0.36 ENSDART00000152775
ENSDART00000152516
ENSDART00000021394
methyltransferase like 13
chr25_+_25516016 0.35 ENSDART00000188980
PHD and ring finger domains 1
chr5_+_31350927 0.35 ENSDART00000028237
calcium/calmodulin-dependent protein kinase kinase 1, alpha a
chr15_+_34592215 0.35 ENSDART00000099776
tetraspanin 13a
chr21_+_30721733 0.35 ENSDART00000040443
zgc:110224
chr21_-_35324091 0.35 ENSDART00000185042
ubiquitin-like domain containing CTD phosphatase 1
chr21_-_11367271 0.35 ENSDART00000151000
ENSDART00000151465
zgc:162472
chr21_-_11054876 0.35 ENSDART00000146576
neural precursor cell expressed, developmentally down-regulated 4-like
chr20_-_39789036 0.35 ENSDART00000086405
ENSDART00000098253
ring finger protein 217
chr4_+_5341592 0.35 ENSDART00000123375
ENSDART00000067371
zgc:113263
chr23_+_16807209 0.35 ENSDART00000141966
zgc:114081
chr8_-_5850472 0.35 ENSDART00000179217

chr12_+_35011899 0.34 ENSDART00000153007
ENSDART00000153020
QKI, KH domain containing, RNA binding 2
chr5_+_71924175 0.34 ENSDART00000115182
ENSDART00000170215
nucleoporin 214
chr4_+_5832311 0.34 ENSDART00000121743
ENSDART00000158233
ENSDART00000165187
si:ch73-352p4.5
chr12_-_16435150 0.34 ENSDART00000086211
polycomb group ring finger 5b
chr11_+_25596038 0.34 ENSDART00000140856
coiled-coil domain containing 120
chr1_+_32051581 0.34 ENSDART00000146602
steroid sulfatase (microsomal), isozyme S
chr19_-_30800004 0.34 ENSDART00000128560
ENSDART00000045504
ENSDART00000125893
tRNA isopentenyltransferase 1
chr19_+_42432625 0.34 ENSDART00000076938
pogo transposable element derived with ZNF domain a
chr16_+_26735894 0.33 ENSDART00000191605
ENSDART00000185175
RAD54 homolog B (S. cerevisiae)
chr14_-_20891745 0.33 ENSDART00000106205
iduronate 2-sulfatase
chr3_+_29476085 0.33 ENSDART00000184495
ENSDART00000181058
family with sequence similarity 83, member Fa
chr1_+_51615672 0.33 ENSDART00000165117
zgc:165656
chr24_-_20321012 0.33 ENSDART00000163683
mitogen-activated protein kinase kinase kinase 20
chr25_+_34407529 0.32 ENSDART00000156751
si:dkey-37f18.2
chr16_-_25368048 0.32 ENSDART00000132445
ribosome binding factor A
chr20_-_38746889 0.32 ENSDART00000140275
tripartite motif containing 54
chr18_-_6534516 0.32 ENSDART00000009217
DEAD/H (Asp-Glu-Ala-Asp/His) box helicase 11
chr25_+_34407740 0.31 ENSDART00000012677
si:dkey-37f18.2
chr6_-_31576397 0.31 ENSDART00000111837
ribonucleoprotein, PTB-binding 2
chr5_-_68244564 0.31 ENSDART00000169350

chr19_-_25772980 0.31 ENSDART00000052393
par-6 family cell polarity regulator gamma b
chr24_-_38644937 0.31 ENSDART00000170194
solute carrier family 6, member 16b
chr21_+_21791799 0.31 ENSDART00000151759
sialidase 3 (membrane sialidase), tandem duplicate 1
chr2_+_43204919 0.31 ENSDART00000160077
ENSDART00000018729
ENSDART00000129134
ENSDART00000056402
par-3 family cell polarity regulator alpha, b
chr12_+_34854562 0.31 ENSDART00000130366
si:dkey-21c1.4
chr10_-_35257458 0.30 ENSDART00000143890
ENSDART00000139107
ENSDART00000082445
proline rich 11
chr18_+_44750170 0.30 ENSDART00000132775
ENSDART00000187468
si:dkey-224e22.2
chr7_-_24644893 0.30 ENSDART00000048921
GP1 homolog, RAB6A GEF complex partner 1
chr5_+_27583445 0.29 ENSDART00000136488
zinc finger, matrin-type 4a
chr20_-_29499363 0.29 ENSDART00000152889
ENSDART00000153252
ENSDART00000170972
ENSDART00000166420
ENSDART00000163079
ribonucleotide reductase M2 polypeptide
chr12_-_10381282 0.29 ENSDART00000152788
marker of proliferation Ki-67
chr22_+_24603930 0.29 ENSDART00000180240
ENSDART00000164256

chr20_+_9474841 0.29 ENSDART00000053847
RAD51 paralog B
chr21_+_40695345 0.29 ENSDART00000143594
coiled-coil domain containing 82
chr13_-_42530656 0.29 ENSDART00000084327
BTAF1 RNA polymerase II, B-TFIID transcription factor-associated
chr2_-_43124747 0.29 ENSDART00000188883
leucine rich repeat containing 6
chr6_-_55399214 0.28 ENSDART00000168367
cathepsin A
chr2_-_20120904 0.28 ENSDART00000186002
ENSDART00000124724
dihydropyrimidine dehydrogenase b
chr6_+_37625787 0.28 ENSDART00000065122
tubulin, gamma complex associated protein 5
chr20_-_2713120 0.28 ENSDART00000138753
ENSDART00000104606
arginyl-tRNA synthetase 2, mitochondrial (putative)

Network of associatons between targets according to the STRING database.

First level regulatory network of pou2f1b

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.7 GO:1904871 positive regulation of protein localization to nucleus(GO:1900182) regulation of protein localization to Cajal body(GO:1904869) positive regulation of protein localization to Cajal body(GO:1904871)
0.2 0.8 GO:0035520 monoubiquitinated protein deubiquitination(GO:0035520) monoubiquitinated histone deubiquitination(GO:0035521) monoubiquitinated histone H2A deubiquitination(GO:0035522)
0.2 0.5 GO:0039529 RIG-I signaling pathway(GO:0039529) regulation of viral-induced cytoplasmic pattern recognition receptor signaling pathway(GO:0039531) regulation of RIG-I signaling pathway(GO:0039535)
0.2 0.6 GO:0090155 regulation of sphingolipid biosynthetic process(GO:0090153) negative regulation of sphingolipid biosynthetic process(GO:0090155) negative regulation of ceramide biosynthetic process(GO:1900060) regulation of membrane lipid metabolic process(GO:1905038) regulation of ceramide biosynthetic process(GO:2000303)
0.2 0.5 GO:0034214 protein hexamerization(GO:0034214) mitotic spindle disassembly(GO:0051228) spindle disassembly(GO:0051230)
0.2 0.5 GO:0019364 pyridine nucleotide catabolic process(GO:0019364) NAD catabolic process(GO:0019677) pyridine-containing compound catabolic process(GO:0072526)
0.1 0.7 GO:0033152 immunoglobulin V(D)J recombination(GO:0033152)
0.1 1.0 GO:1990511 piRNA biosynthetic process(GO:1990511)
0.1 1.0 GO:0031113 regulation of microtubule polymerization(GO:0031113)
0.1 0.5 GO:0006843 mitochondrial citrate transport(GO:0006843)
0.1 0.7 GO:0035093 spermatid nucleus differentiation(GO:0007289) regulation of transposition(GO:0010528) negative regulation of transposition(GO:0010529) sperm chromatin condensation(GO:0035092) spermatogenesis, exchange of chromosomal proteins(GO:0035093)
0.1 0.5 GO:0015722 canalicular bile acid transport(GO:0015722) bile acid secretion(GO:0032782)
0.1 0.7 GO:0060149 negative regulation of posttranscriptional gene silencing(GO:0060149) negative regulation of gene silencing by miRNA(GO:0060965) negative regulation of gene silencing by RNA(GO:0060967)
0.1 0.3 GO:1901836 regulation of transcription of nuclear large rRNA transcript from RNA polymerase I promoter(GO:1901836)
0.1 0.3 GO:0048200 COPI-coated vesicle budding(GO:0035964) Golgi transport vesicle coating(GO:0048200) COPI coating of Golgi vesicle(GO:0048205)
0.1 0.3 GO:0009120 deoxyribonucleoside metabolic process(GO:0009120) thymidine metabolic process(GO:0046104) pyrimidine deoxyribonucleoside metabolic process(GO:0046125)
0.1 0.7 GO:2000650 negative regulation of sodium ion transmembrane transporter activity(GO:2000650)
0.1 0.8 GO:0072386 plus-end-directed vesicle transport along microtubule(GO:0072383) plus-end-directed organelle transport along microtubule(GO:0072386)
0.1 0.3 GO:0035971 peptidyl-histidine dephosphorylation(GO:0035971)
0.1 1.2 GO:0090110 cargo loading into COPII-coated vesicle(GO:0090110)
0.1 0.3 GO:0051660 establishment of centrosome localization(GO:0051660)
0.1 0.3 GO:0042776 mitochondrial ATP synthesis coupled proton transport(GO:0042776)
0.1 0.6 GO:0033314 mitotic DNA replication checkpoint(GO:0033314)
0.1 0.2 GO:0060912 cardiac cell fate specification(GO:0060912)
0.1 0.2 GO:0009162 deoxyribonucleoside monophosphate metabolic process(GO:0009162)
0.1 0.3 GO:0000012 single strand break repair(GO:0000012)
0.1 0.3 GO:0006272 leading strand elongation(GO:0006272)
0.1 0.9 GO:1990504 dense core granule exocytosis(GO:1990504)
0.1 0.3 GO:0006384 transcription initiation from RNA polymerase III promoter(GO:0006384)
0.1 0.3 GO:0006530 asparagine catabolic process(GO:0006530) asparagine catabolic process via L-aspartate(GO:0033345)
0.1 0.2 GO:0042671 retinal cone cell fate determination(GO:0042671) eye photoreceptor cell fate commitment(GO:0042706) photoreceptor cell fate determination(GO:0043703) retinal cone cell fate commitment(GO:0046551) photoreceptor cell fate commitment(GO:0046552) camera-type eye photoreceptor cell fate commitment(GO:0060220)
0.1 0.6 GO:0006517 protein deglycosylation(GO:0006517)
0.1 0.5 GO:0003422 growth plate cartilage morphogenesis(GO:0003422) chondrocyte intercalation involved in growth plate cartilage morphogenesis(GO:0003428)
0.1 0.2 GO:0071871 response to monoamine(GO:0071867) response to catecholamine(GO:0071869) response to epinephrine(GO:0071871)
0.1 0.2 GO:2001244 positive regulation of intrinsic apoptotic signaling pathway(GO:2001244)
0.1 0.2 GO:0071675 regulation of macrophage chemotaxis(GO:0010758) positive regulation of macrophage chemotaxis(GO:0010759) skeletal muscle cell proliferation(GO:0014856) regulation of skeletal muscle cell proliferation(GO:0014857) mononuclear cell migration(GO:0071674) regulation of mononuclear cell migration(GO:0071675) positive regulation of lamellipodium organization(GO:1902745)
0.1 0.2 GO:1900364 negative regulation of mRNA 3'-end processing(GO:0031441) negative regulation of mRNA polyadenylation(GO:1900364)
0.1 0.2 GO:0071387 cellular response to cortisol stimulus(GO:0071387) response to dexamethasone(GO:0071548)
0.1 0.2 GO:0031446 regulation of twitch skeletal muscle contraction(GO:0014724) regulation of fast-twitch skeletal muscle fiber contraction(GO:0031446) positive regulation of fast-twitch skeletal muscle fiber contraction(GO:0031448) negative regulation of striated muscle contraction(GO:0045988) relaxation of skeletal muscle(GO:0090076)
0.0 0.2 GO:0048210 Golgi vesicle fusion to target membrane(GO:0048210)
0.0 0.2 GO:0043102 L-methionine biosynthetic process from methylthioadenosine(GO:0019509) amino acid salvage(GO:0043102) L-methionine biosynthetic process(GO:0071265) L-methionine salvage(GO:0071267)
0.0 0.3 GO:0060343 trabecula formation(GO:0060343) heart trabecula formation(GO:0060347)
0.0 0.3 GO:0030579 ubiquitin-dependent SMAD protein catabolic process(GO:0030579)
0.0 0.3 GO:0006004 fucose metabolic process(GO:0006004)
0.0 0.6 GO:0032483 regulation of Rab protein signal transduction(GO:0032483)
0.0 0.2 GO:0006844 acyl carnitine transport(GO:0006844)
0.0 0.7 GO:2000369 regulation of clathrin-mediated endocytosis(GO:2000369)
0.0 0.2 GO:1904036 negative regulation of epithelial cell apoptotic process(GO:1904036)
0.0 0.1 GO:0090200 regulation of release of cytochrome c from mitochondria(GO:0090199) positive regulation of release of cytochrome c from mitochondria(GO:0090200)
0.0 0.1 GO:0006409 tRNA export from nucleus(GO:0006409) tRNA-containing ribonucleoprotein complex export from nucleus(GO:0071431)
0.0 0.6 GO:0060046 binding of sperm to zona pellucida(GO:0007339) egg coat formation(GO:0035803) regulation of acrosome reaction(GO:0060046) positive regulation of acrosome reaction(GO:2000344)
0.0 0.3 GO:0039023 pronephric duct morphogenesis(GO:0039023)
0.0 0.2 GO:0019563 glycerol catabolic process(GO:0019563)
0.0 0.3 GO:0000290 deadenylation-dependent decapping of nuclear-transcribed mRNA(GO:0000290)
0.0 0.1 GO:1901052 sarcosine metabolic process(GO:1901052)
0.0 0.2 GO:0007191 adenylate cyclase-activating dopamine receptor signaling pathway(GO:0007191)
0.0 0.2 GO:0009249 protein lipoylation(GO:0009249)
0.0 0.3 GO:0009263 deoxyribonucleotide biosynthetic process(GO:0009263)
0.0 0.7 GO:0010962 regulation of glycogen biosynthetic process(GO:0005979) regulation of glucan biosynthetic process(GO:0010962)
0.0 0.3 GO:0048696 collateral sprouting in absence of injury(GO:0048669) regulation of collateral sprouting in absence of injury(GO:0048696)
0.0 0.2 GO:0006011 UDP-glucose metabolic process(GO:0006011)
0.0 0.5 GO:0021988 olfactory bulb development(GO:0021772) olfactory lobe development(GO:0021988)
0.0 0.1 GO:0046952 ketone body catabolic process(GO:0046952)
0.0 0.3 GO:0036353 histone H2A-K119 monoubiquitination(GO:0036353)
0.0 0.2 GO:0070933 histone H4 deacetylation(GO:0070933)
0.0 0.6 GO:0006684 sphingomyelin metabolic process(GO:0006684)
0.0 0.2 GO:0006627 protein processing involved in protein targeting to mitochondrion(GO:0006627)
0.0 0.3 GO:0009313 oligosaccharide catabolic process(GO:0009313)
0.0 0.6 GO:0015701 bicarbonate transport(GO:0015701)
0.0 0.7 GO:0007568 aging(GO:0007568)
0.0 0.2 GO:0030242 pexophagy(GO:0030242)
0.0 0.2 GO:0044209 AMP salvage(GO:0044209)
0.0 0.2 GO:0018202 histone H3-K36 methylation(GO:0010452) peptidyl-histidine modification(GO:0018202)
0.0 0.3 GO:0048845 venous blood vessel morphogenesis(GO:0048845)
0.0 0.3 GO:0034394 protein localization to cell surface(GO:0034394)
0.0 0.4 GO:0006003 fructose 2,6-bisphosphate metabolic process(GO:0006003)
0.0 0.3 GO:1904356 regulation of telomere maintenance via telomere lengthening(GO:1904356)
0.0 0.4 GO:0036092 phosphatidylinositol-3-phosphate biosynthetic process(GO:0036092)
0.0 0.4 GO:0051310 metaphase plate congression(GO:0051310)
0.0 0.6 GO:0043666 regulation of phosphoprotein phosphatase activity(GO:0043666)
0.0 0.1 GO:0016188 synaptic vesicle maturation(GO:0016188)
0.0 0.4 GO:0071456 cellular response to hypoxia(GO:0071456)
0.0 0.5 GO:0001966 thigmotaxis(GO:0001966)
0.0 0.4 GO:0016558 protein import into peroxisome matrix(GO:0016558)
0.0 0.4 GO:0034629 cellular protein complex localization(GO:0034629)
0.0 1.4 GO:0006606 protein import into nucleus(GO:0006606) protein targeting to nucleus(GO:0044744) single-organism nuclear import(GO:1902593)
0.0 0.2 GO:1901096 regulation of autophagosome maturation(GO:1901096)
0.0 0.1 GO:0048011 neurotrophin TRK receptor signaling pathway(GO:0048011)
0.0 0.2 GO:0060217 hemangioblast cell differentiation(GO:0060217)
0.0 0.1 GO:0072498 embryonic skeletal joint development(GO:0072498)
0.0 0.3 GO:0008345 larval locomotory behavior(GO:0008345) larval behavior(GO:0030537)
0.0 0.4 GO:0048814 regulation of dendrite morphogenesis(GO:0048814)
0.0 0.4 GO:0006446 regulation of translational initiation(GO:0006446)
0.0 0.1 GO:0070129 regulation of mitochondrial translation(GO:0070129) positive regulation of mitochondrial translation(GO:0070131)
0.0 0.1 GO:0070586 cell-cell adhesion involved in gastrulation(GO:0070586)
0.0 1.1 GO:0006414 translational elongation(GO:0006414)
0.0 0.1 GO:0051290 protein heterotetramerization(GO:0051290)
0.0 0.5 GO:0030307 positive regulation of cell growth(GO:0030307)
0.0 0.1 GO:0071156 regulation of cell cycle arrest(GO:0071156)
0.0 0.2 GO:1902624 positive regulation of neutrophil migration(GO:1902624)
0.0 0.3 GO:0006658 phosphatidylserine metabolic process(GO:0006658)
0.0 0.2 GO:0034724 DNA replication-independent nucleosome organization(GO:0034724)
0.0 0.8 GO:0042147 retrograde transport, endosome to Golgi(GO:0042147)
0.0 0.8 GO:0051028 mRNA transport(GO:0051028)
0.0 0.4 GO:0048268 clathrin coat assembly(GO:0048268)
0.0 0.1 GO:0071543 diphosphoinositol polyphosphate metabolic process(GO:0071543) diadenosine pentaphosphate metabolic process(GO:1901906) diadenosine pentaphosphate catabolic process(GO:1901907) diadenosine hexaphosphate metabolic process(GO:1901908) diadenosine hexaphosphate catabolic process(GO:1901909) adenosine 5'-(hexahydrogen pentaphosphate) metabolic process(GO:1901910) adenosine 5'-(hexahydrogen pentaphosphate) catabolic process(GO:1901911)
0.0 0.8 GO:0031122 cytoplasmic microtubule organization(GO:0031122)
0.0 0.6 GO:0000281 mitotic cytokinesis(GO:0000281)
0.0 0.2 GO:0019433 triglyceride catabolic process(GO:0019433)
0.0 0.1 GO:0072088 renal tubule morphogenesis(GO:0061333) nephron tubule morphogenesis(GO:0072078) nephron epithelium morphogenesis(GO:0072088)
0.0 0.3 GO:0034626 fatty acid elongation, saturated fatty acid(GO:0019367) fatty acid elongation, unsaturated fatty acid(GO:0019368) fatty acid elongation, monounsaturated fatty acid(GO:0034625) fatty acid elongation, polyunsaturated fatty acid(GO:0034626)
0.0 0.2 GO:0046475 glycerophospholipid catabolic process(GO:0046475)
0.0 0.3 GO:0006418 tRNA aminoacylation for protein translation(GO:0006418)
0.0 0.1 GO:0030728 ovulation(GO:0030728)
0.0 0.2 GO:0019985 translesion synthesis(GO:0019985)
0.0 0.3 GO:0032786 positive regulation of DNA-templated transcription, elongation(GO:0032786)
0.0 0.2 GO:0006298 mismatch repair(GO:0006298)
0.0 0.1 GO:1900145 nodal signaling pathway involved in determination of left/right asymmetry(GO:0038107) regulation of nodal signaling pathway involved in determination of left/right asymmetry(GO:1900145)
0.0 0.6 GO:0007131 reciprocal meiotic recombination(GO:0007131)
0.0 0.2 GO:1902287 semaphorin-plexin signaling pathway involved in neuron projection guidance(GO:1902285) semaphorin-plexin signaling pathway involved in axon guidance(GO:1902287)
0.0 0.3 GO:0030512 negative regulation of transforming growth factor beta receptor signaling pathway(GO:0030512) negative regulation of cellular response to transforming growth factor beta stimulus(GO:1903845)
0.0 0.4 GO:0009648 photoperiodism(GO:0009648)
0.0 0.1 GO:0018023 peptidyl-lysine trimethylation(GO:0018023)
0.0 0.2 GO:0046688 response to copper ion(GO:0046688)
0.0 0.2 GO:0035476 angioblast cell migration(GO:0035476)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.7 GO:0043073 germ cell nucleus(GO:0043073)
0.2 0.6 GO:0035339 SPOTS complex(GO:0035339)
0.1 0.4 GO:0034663 endoplasmic reticulum chaperone complex(GO:0034663)
0.1 0.5 GO:0097519 DNA recombinase complex(GO:0097519)
0.1 1.0 GO:0005665 DNA-directed RNA polymerase II, core complex(GO:0005665)
0.1 0.4 GO:1990513 CLOCK-BMAL transcription complex(GO:1990513)
0.1 0.3 GO:0000931 gamma-tubulin large complex(GO:0000931) gamma-tubulin ring complex(GO:0008274)
0.1 0.5 GO:0031931 TORC1 complex(GO:0031931)
0.1 1.2 GO:0030127 COPII vesicle coat(GO:0030127)
0.1 0.3 GO:0033063 Rad51B-Rad51C-Rad51D-XRCC2 complex(GO:0033063)
0.1 0.3 GO:0005658 alpha DNA polymerase:primase complex(GO:0005658)
0.1 0.2 GO:0031673 H zone(GO:0031673)
0.1 0.5 GO:0036449 microtubule minus-end(GO:0036449)
0.1 0.6 GO:0005664 origin recognition complex(GO:0000808) nuclear origin of replication recognition complex(GO:0005664)
0.0 0.2 GO:0070724 BMP receptor complex(GO:0070724)
0.0 0.2 GO:0098890 extrinsic component of postsynaptic membrane(GO:0098890)
0.0 0.4 GO:0005943 phosphatidylinositol 3-kinase complex, class IA(GO:0005943)
0.0 0.3 GO:0000126 transcription factor TFIIIB complex(GO:0000126)
0.0 0.7 GO:0000164 protein phosphatase type 1 complex(GO:0000164)
0.0 0.7 GO:0005801 cis-Golgi network(GO:0005801)
0.0 0.2 GO:1990316 ATG1/ULK1 kinase complex(GO:1990316)
0.0 0.1 GO:0034456 CURI complex(GO:0032545) UTP-C complex(GO:0034456)
0.0 0.3 GO:0032045 guanyl-nucleotide exchange factor complex(GO:0032045)
0.0 0.2 GO:0042720 mitochondrial inner membrane peptidase complex(GO:0042720)
0.0 0.3 GO:1990726 Lsm1-7-Pat1 complex(GO:1990726)
0.0 0.3 GO:0019908 cyclin/CDK positive transcription elongation factor complex(GO:0008024) nuclear cyclin-dependent protein kinase holoenzyme complex(GO:0019908)
0.0 0.2 GO:0030670 phagocytic vesicle membrane(GO:0030670)
0.0 0.4 GO:0048179 activin receptor complex(GO:0048179)
0.0 0.1 GO:0032584 growth cone membrane(GO:0032584)
0.0 0.4 GO:0000124 SAGA complex(GO:0000124)
0.0 0.3 GO:0070187 telosome(GO:0070187)
0.0 0.7 GO:0043186 P granule(GO:0043186)
0.0 0.3 GO:0097610 cleavage furrow(GO:0032154) cell surface furrow(GO:0097610)
0.0 0.2 GO:0000109 nucleotide-excision repair complex(GO:0000109)
0.0 0.5 GO:0032156 septin ring(GO:0005940) septin complex(GO:0031105) septin cytoskeleton(GO:0032156)
0.0 0.2 GO:0045171 intercellular bridge(GO:0045171)
0.0 0.7 GO:0098978 glutamatergic synapse(GO:0098978)
0.0 0.1 GO:0031313 extrinsic component of endosome membrane(GO:0031313)
0.0 0.3 GO:0097546 ciliary base(GO:0097546)
0.0 1.3 GO:0005871 kinesin complex(GO:0005871)
0.0 0.5 GO:0005844 polysome(GO:0005844)
0.0 0.8 GO:0030496 midbody(GO:0030496)
0.0 0.5 GO:0035861 site of double-strand break(GO:0035861)
0.0 0.3 GO:0035102 PRC1 complex(GO:0035102)
0.0 0.8 GO:0005643 nuclear pore(GO:0005643)
0.0 0.3 GO:0044666 MLL3/4 complex(GO:0044666)
0.0 0.1 GO:0031616 spindle pole centrosome(GO:0031616)
0.0 0.3 GO:0001917 photoreceptor inner segment(GO:0001917)
0.0 0.2 GO:0016281 eukaryotic translation initiation factor 4F complex(GO:0016281)
0.0 0.2 GO:0030057 desmosome(GO:0030057)
0.0 0.2 GO:0032039 integrator complex(GO:0032039)
0.0 0.3 GO:0030140 trans-Golgi network transport vesicle(GO:0030140)
0.0 0.2 GO:0002116 semaphorin receptor complex(GO:0002116)
0.0 0.4 GO:0000307 cyclin-dependent protein kinase holoenzyme complex(GO:0000307)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.5 GO:0008454 alpha-1,3-mannosylglycoprotein 4-beta-N-acetylglucosaminyltransferase activity(GO:0008454)
0.2 0.5 GO:0005547 phosphatidylinositol-3,4,5-trisphosphate binding(GO:0005547)
0.2 0.5 GO:0008386 cholesterol monooxygenase (side-chain-cleaving) activity(GO:0008386) oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced iron-sulfur protein as one donor, and incorporation of one atom of oxygen(GO:0016713)
0.1 0.4 GO:0016509 long-chain-3-hydroxyacyl-CoA dehydrogenase activity(GO:0016509)
0.1 1.0 GO:0004366 glycerol-3-phosphate O-acyltransferase activity(GO:0004366)
0.1 0.5 GO:0048487 beta-tubulin binding(GO:0048487)
0.1 0.5 GO:0015126 canalicular bile acid transmembrane transporter activity(GO:0015126) bile acid-exporting ATPase activity(GO:0015432)
0.1 0.3 GO:0033130 acetylcholine receptor binding(GO:0033130)
0.1 0.7 GO:0019871 sodium channel inhibitor activity(GO:0019871)
0.1 0.7 GO:0034584 piRNA binding(GO:0034584)
0.1 0.2 GO:0050253 retinyl-palmitate esterase activity(GO:0050253)
0.1 0.3 GO:0101006 protein histidine phosphatase activity(GO:0101006)
0.1 0.3 GO:0004565 beta-galactosidase activity(GO:0004565)
0.1 0.4 GO:0003836 beta-galactoside (CMP) alpha-2,3-sialyltransferase activity(GO:0003836)
0.1 0.6 GO:0035804 structural constituent of egg coat(GO:0035804)
0.1 0.3 GO:0004185 serine-type carboxypeptidase activity(GO:0004185)
0.1 0.3 GO:0017113 uracil binding(GO:0002058) pyrimidine nucleobase binding(GO:0002061) dihydropyrimidine dehydrogenase (NADP+) activity(GO:0017113)
0.1 0.3 GO:0015616 DNA translocase activity(GO:0015616)
0.1 0.3 GO:0008798 beta-aspartyl-peptidase activity(GO:0008798)
0.1 0.4 GO:0070888 E-box binding(GO:0070888)
0.0 0.4 GO:0008494 translation activator activity(GO:0008494)
0.0 0.7 GO:2001069 glycogen binding(GO:2001069)
0.0 0.5 GO:0030296 protein tyrosine kinase activator activity(GO:0030296)
0.0 0.5 GO:0035612 AP-2 adaptor complex binding(GO:0035612)
0.0 0.9 GO:0008139 nuclear localization sequence binding(GO:0008139)
0.0 0.2 GO:0015227 acyl carnitine transmembrane transporter activity(GO:0015227)
0.0 0.5 GO:0008422 beta-glucosidase activity(GO:0008422)
0.0 0.6 GO:0008510 sodium:bicarbonate symporter activity(GO:0008510)
0.0 0.3 GO:0016728 ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor(GO:0004748) oxidoreductase activity, acting on CH or CH2 groups, disulfide as acceptor(GO:0016728) ribonucleoside-diphosphate reductase activity(GO:0061731)
0.0 1.1 GO:0003899 DNA-directed RNA polymerase activity(GO:0003899) RNA polymerase activity(GO:0034062)
0.0 0.6 GO:0004767 sphingomyelin phosphodiesterase activity(GO:0004767)
0.0 0.1 GO:0005252 open rectifier potassium channel activity(GO:0005252)
0.0 0.8 GO:0070122 isopeptidase activity(GO:0070122)
0.0 0.4 GO:0046934 phosphatidylinositol-4,5-bisphosphate 3-kinase activity(GO:0046934) phosphatidylinositol-3,4-bisphosphate 5-kinase activity(GO:0052812)
0.0 0.8 GO:0051011 microtubule minus-end binding(GO:0051011)
0.0 0.3 GO:0035613 RNA stem-loop binding(GO:0035613)
0.0 0.1 GO:0043621 protein self-association(GO:0043621)
0.0 0.2 GO:0016531 copper chaperone activity(GO:0016531)
0.0 0.9 GO:0003688 DNA replication origin binding(GO:0003688)
0.0 1.5 GO:0003746 translation elongation factor activity(GO:0003746)
0.0 0.8 GO:0042800 histone methyltransferase activity (H3-K4 specific)(GO:0042800)
0.0 0.5 GO:0004724 magnesium-dependent protein serine/threonine phosphatase activity(GO:0004724)
0.0 0.2 GO:0035529 NADH pyrophosphatase activity(GO:0035529)
0.0 0.2 GO:0051748 UTP:glucose-1-phosphate uridylyltransferase activity(GO:0003983) UTP-monosaccharide-1-phosphate uridylyltransferase activity(GO:0051748)
0.0 0.2 GO:0004001 adenosine kinase activity(GO:0004001)
0.0 0.5 GO:0003906 DNA-(apurinic or apyrimidinic site) lyase activity(GO:0003906)
0.0 0.1 GO:0008260 3-oxoacid CoA-transferase activity(GO:0008260)
0.0 0.3 GO:0000400 four-way junction DNA binding(GO:0000400)
0.0 0.4 GO:0003873 6-phosphofructo-2-kinase activity(GO:0003873)
0.0 0.3 GO:0052796 exo-alpha-(2->3)-sialidase activity(GO:0052794) exo-alpha-(2->6)-sialidase activity(GO:0052795) exo-alpha-(2->8)-sialidase activity(GO:0052796)
0.0 0.3 GO:0046933 proton-transporting ATP synthase activity, rotational mechanism(GO:0046933)
0.0 0.7 GO:0008171 O-methyltransferase activity(GO:0008171)
0.0 0.4 GO:0070840 dynein complex binding(GO:0070840)
0.0 0.1 GO:0046997 oxidoreductase activity, acting on the CH-NH group of donors, flavin as acceptor(GO:0046997)
0.0 0.2 GO:0004731 purine-nucleoside phosphorylase activity(GO:0004731)
0.0 0.8 GO:0008484 sulfuric ester hydrolase activity(GO:0008484)
0.0 0.2 GO:0036137 kynurenine-oxoglutarate transaminase activity(GO:0016212) kynurenine aminotransferase activity(GO:0036137)
0.0 0.4 GO:0017002 activin-activated receptor activity(GO:0017002)
0.0 0.2 GO:0034597 phosphatidylinositol-4,5-bisphosphate 4-phosphatase activity(GO:0034597)
0.0 0.1 GO:0016427 tRNA (cytosine) methyltransferase activity(GO:0016427)
0.0 0.4 GO:0004703 G-protein coupled receptor kinase activity(GO:0004703)
0.0 0.2 GO:0005025 transforming growth factor beta receptor activity, type I(GO:0005025)
0.0 0.5 GO:0017056 structural constituent of nuclear pore(GO:0017056)
0.0 0.2 GO:0004839 ubiquitin activating enzyme activity(GO:0004839)
0.0 0.2 GO:0052658 inositol-1,4,5-trisphosphate 5-phosphatase activity(GO:0052658)
0.0 0.3 GO:0061575 cyclin-dependent protein serine/threonine kinase activator activity(GO:0061575)
0.0 0.2 GO:0043325 phosphatidylinositol-3,4-bisphosphate binding(GO:0043325)
0.0 0.1 GO:0004345 glucose-6-phosphate dehydrogenase activity(GO:0004345)
0.0 0.2 GO:0047498 calcium-dependent phospholipase A2 activity(GO:0047498)
0.0 0.2 GO:0015926 glucosidase activity(GO:0015926)
0.0 0.2 GO:0016783 sulfurtransferase activity(GO:0016783)
0.0 0.1 GO:0043015 gamma-tubulin binding(GO:0043015)
0.0 0.6 GO:0003684 damaged DNA binding(GO:0003684)
0.0 0.3 GO:0005080 protein kinase C binding(GO:0005080)
0.0 0.2 GO:0032041 histone deacetylase activity (H3-K14 specific)(GO:0031078) NAD-dependent histone deacetylase activity (H3-K14 specific)(GO:0032041)
0.0 0.3 GO:0008417 fucosyltransferase activity(GO:0008417)
0.0 1.3 GO:0003777 microtubule motor activity(GO:0003777)
0.0 0.1 GO:0008486 endopolyphosphatase activity(GO:0000298) diphosphoinositol-polyphosphate diphosphatase activity(GO:0008486) bis(5'-adenosyl)-hexaphosphatase activity(GO:0034431) bis(5'-adenosyl)-pentaphosphatase activity(GO:0034432)
0.0 0.1 GO:0004142 diacylglycerol cholinephosphotransferase activity(GO:0004142) ethanolaminephosphotransferase activity(GO:0004307)
0.0 0.2 GO:0008553 hydrogen-exporting ATPase activity, phosphorylative mechanism(GO:0008553)
0.0 0.3 GO:0009922 fatty acid elongase activity(GO:0009922) 3-oxo-arachidoyl-CoA synthase activity(GO:0102336) 3-oxo-cerotoyl-CoA synthase activity(GO:0102337) 3-oxo-lignoceronyl-CoA synthase activity(GO:0102338)
0.0 0.4 GO:0051018 protein kinase A binding(GO:0051018)
0.0 0.0 GO:0047690 aspartyltransferase activity(GO:0047690)
0.0 0.5 GO:0051959 dynein light intermediate chain binding(GO:0051959)
0.0 0.3 GO:0042162 telomeric DNA binding(GO:0042162)
0.0 0.3 GO:0016876 aminoacyl-tRNA ligase activity(GO:0004812) ligase activity, forming carbon-oxygen bonds(GO:0016875) ligase activity, forming aminoacyl-tRNA and related compounds(GO:0016876)
0.0 0.2 GO:0004169 dolichyl-phosphate-mannose-protein mannosyltransferase activity(GO:0004169)
0.0 0.5 GO:0017124 SH3 domain binding(GO:0017124)
0.0 0.4 GO:0031624 ubiquitin conjugating enzyme binding(GO:0031624)
0.0 0.2 GO:0031682 G-protein gamma-subunit binding(GO:0031682)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.4 PID P38 MKK3 6PATHWAY p38 MAPK signaling pathway
0.0 0.7 PID HEDGEHOG 2PATHWAY Signaling events mediated by the Hedgehog family
0.0 0.4 PID IL8 CXCR1 PATHWAY IL8- and CXCR1-mediated signaling events
0.0 1.2 PID PLK1 PATHWAY PLK1 signaling events
0.0 0.3 PID SMAD2 3PATHWAY Regulation of cytoplasmic and nuclear SMAD2/3 signaling
0.0 0.5 SA PTEN PATHWAY PTEN is a tumor suppressor that dephosphorylates the lipid messenger phosphatidylinositol triphosphate.
0.0 1.0 PID TGFBR PATHWAY TGF-beta receptor signaling
0.0 0.3 PID SYNDECAN 4 PATHWAY Syndecan-4-mediated signaling events
0.0 1.3 PID E2F PATHWAY E2F transcription factor network
0.0 0.6 PID CDC42 REG PATHWAY Regulation of CDC42 activity
0.0 0.2 SA G1 AND S PHASES Cdk2, 4, and 6 bind cyclin D in G1, while cdk2/cyclin E promotes the G1/S transition.
0.0 0.7 PID MET PATHWAY Signaling events mediated by Hepatocyte Growth Factor Receptor (c-Met)
0.0 0.2 PID PI3KCI AKT PATHWAY Class I PI3K signaling events mediated by Akt
0.0 0.2 PID NFAT TFPATHWAY Calcineurin-regulated NFAT-dependent transcription in lymphocytes
0.0 0.6 PID CMYB PATHWAY C-MYB transcription factor network
0.0 0.1 PID AURORA A PATHWAY Aurora A signaling
0.0 0.1 SIG CD40PATHWAYMAP Genes related to CD40 signaling

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.0 REACTOME THE ACTIVATION OF ARYLSULFATASES Genes involved in The activation of arylsulfatases
0.1 0.9 REACTOME ACTIVATION OF IRF3 IRF7 MEDIATED BY TBK1 IKK EPSILON Genes involved in Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon
0.1 1.0 REACTOME VIRAL MESSENGER RNA SYNTHESIS Genes involved in Viral Messenger RNA Synthesis
0.1 0.5 REACTOME ENDOGENOUS STEROLS Genes involved in Endogenous sterols
0.1 1.0 REACTOME ANTIGEN PRESENTATION FOLDING ASSEMBLY AND PEPTIDE LOADING OF CLASS I MHC Genes involved in Antigen Presentation: Folding, assembly and peptide loading of class I MHC
0.0 0.8 REACTOME N GLYCAN TRIMMING IN THE ER AND CALNEXIN CALRETICULIN CYCLE Genes involved in N-glycan trimming in the ER and Calnexin/Calreticulin cycle
0.0 0.5 REACTOME MTORC1 MEDIATED SIGNALLING Genes involved in mTORC1-mediated signalling
0.0 1.2 REACTOME G1 S SPECIFIC TRANSCRIPTION Genes involved in G1/S-Specific Transcription
0.0 0.9 REACTOME SYNTHESIS OF PA Genes involved in Synthesis of PA
0.0 0.8 REACTOME KINESINS Genes involved in Kinesins
0.0 0.7 REACTOME FGFR LIGAND BINDING AND ACTIVATION Genes involved in FGFR ligand binding and activation
0.0 0.4 REACTOME KERATAN SULFATE BIOSYNTHESIS Genes involved in Keratan sulfate biosynthesis
0.0 0.3 REACTOME RECRUITMENT OF NUMA TO MITOTIC CENTROSOMES Genes involved in Recruitment of NuMA to mitotic centrosomes
0.0 0.3 REACTOME CS DS DEGRADATION Genes involved in CS/DS degradation
0.0 0.4 REACTOME DEADENYLATION OF MRNA Genes involved in Deadenylation of mRNA
0.0 0.2 REACTOME CYCLIN A B1 ASSOCIATED EVENTS DURING G2 M TRANSITION Genes involved in Cyclin A/B1 associated events during G2/M transition
0.0 0.3 REACTOME SIGNALING BY BMP Genes involved in Signaling by BMP
0.0 0.3 REACTOME PROTEOLYTIC CLEAVAGE OF SNARE COMPLEX PROTEINS Genes involved in Proteolytic cleavage of SNARE complex proteins
0.0 0.5 REACTOME N GLYCAN ANTENNAE ELONGATION Genes involved in N-Glycan antennae elongation
0.0 0.4 REACTOME G BETA GAMMA SIGNALLING THROUGH PI3KGAMMA Genes involved in G beta:gamma signalling through PI3Kgamma
0.0 0.7 REACTOME ACTIVATION OF CHAPERONE GENES BY XBP1S Genes involved in Activation of Chaperone Genes by XBP1(S)
0.0 0.2 REACTOME SYNTHESIS SECRETION AND DEACYLATION OF GHRELIN Genes involved in Synthesis, Secretion, and Deacylation of Ghrelin
0.0 0.2 REACTOME METABOLISM OF POLYAMINES Genes involved in Metabolism of polyamines
0.0 0.2 REACTOME AKT PHOSPHORYLATES TARGETS IN THE CYTOSOL Genes involved in AKT phosphorylates targets in the cytosol
0.0 0.6 REACTOME PRE NOTCH EXPRESSION AND PROCESSING Genes involved in Pre-NOTCH Expression and Processing
0.0 0.3 REACTOME MRNA DECAY BY 5 TO 3 EXORIBONUCLEASE Genes involved in mRNA Decay by 5' to 3' Exoribonuclease
0.0 0.2 REACTOME TRYPTOPHAN CATABOLISM Genes involved in Tryptophan catabolism
0.0 0.3 REACTOME GLYCOSPHINGOLIPID METABOLISM Genes involved in Glycosphingolipid metabolism
0.0 0.3 REACTOME MITOCHONDRIAL TRNA AMINOACYLATION Genes involved in Mitochondrial tRNA aminoacylation
0.0 0.2 REACTOME PYRIMIDINE METABOLISM Genes involved in Pyrimidine metabolism
0.0 0.2 REACTOME OTHER SEMAPHORIN INTERACTIONS Genes involved in Other semaphorin interactions
0.0 0.4 REACTOME NETRIN1 SIGNALING Genes involved in Netrin-1 signaling
0.0 0.1 REACTOME PEPTIDE HORMONE BIOSYNTHESIS Genes involved in Peptide hormone biosynthesis
0.0 0.2 REACTOME FORMATION OF INCISION COMPLEX IN GG NER Genes involved in Formation of incision complex in GG-NER