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PRJNA195909:zebrafish embryo and larva development
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Results for pax8
Z-value: 1.36
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Transcription factors associated with pax8
Activity-expression correlation:
| Gene | Promoter | Pearson corr. coef. | P-value | Plot |
|---|---|---|---|---|
| pax8 | dr11_v1_chr5_-_72415578_72415578 | 0.83 | 5.7e-03 | Click! |
| Promoter | Log-likelihood | Transcript | Gene | Gene Info |
|---|---|---|---|---|
| chr16_+_23487051 Show fit | 5.45 |
ENSDART00000145496
|
ictacalcin 2 |
|
| chr4_+_25630555 Show fit | 2.21 |
ENSDART00000133425
|
acyl-CoA thioesterase 15 |
|
| chr9_+_23665777 Show fit | 1.94 |
ENSDART00000060905
|
glycophorin C (Gerbich blood group) |
|
| chr5_+_23630384 Show fit | 1.82 |
ENSDART00000013745
|
connexin 39.9 |
|
| chr7_+_10610791 Show fit | 1.59 |
ENSDART00000166064
|
fumarylacetoacetate hydrolase (fumarylacetoacetase) |
|
| chr23_+_43255328 Show fit | 1.45 |
ENSDART00000102712
|
transglutaminase 2, C polypeptide A |
|
| chr1_-_30457062 Show fit | 1.40 |
ENSDART00000185318
ENSDART00000157924 ENSDART00000161380 |
insulin-like growth factor 2 mRNA binding protein 2b |
|
| chr6_-_47840465 Show fit | 1.35 |
ENSDART00000141986
|
leucine-rich repeats and immunoglobulin-like domains 2 |
|
| chr9_+_39027123 Show fit | 1.30 |
ENSDART00000004742
|
carbamoyl-phosphate synthase 1, mitochondrial |
|
| chr23_+_26733232 Show fit | 1.29 |
ENSDART00000035080
|
zgc:158263 |
Network of associatons between targets according to the STRING database.
First level regulatory network of pax8
Gene Ontology Analysis
Gene overrepresentation in biological process category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 5.4 | GO:0021782 | glial cell development(GO:0021782) |
| 0.5 | 2.4 | GO:0097272 | ammonia homeostasis(GO:0097272) |
| 0.3 | 1.6 | GO:0006572 | tyrosine catabolic process(GO:0006572) |
| 0.1 | 1.5 | GO:0018149 | peptide cross-linking(GO:0018149) |
| 0.0 | 1.3 | GO:0006672 | ceramide metabolic process(GO:0006672) |
| 0.4 | 1.2 | GO:0061341 | non-canonical Wnt signaling pathway involved in heart development(GO:0061341) |
| 0.2 | 1.1 | GO:0045736 | negative regulation of cyclin-dependent protein serine/threonine kinase activity(GO:0045736) negative regulation of cyclin-dependent protein kinase activity(GO:1904030) |
| 0.0 | 1.1 | GO:0044243 | collagen catabolic process(GO:0030574) multicellular organism catabolic process(GO:0044243) |
| 0.0 | 1.1 | GO:0000387 | spliceosomal snRNP assembly(GO:0000387) |
| 0.0 | 1.1 | GO:0006637 | acyl-CoA metabolic process(GO:0006637) thioester metabolic process(GO:0035383) |
Gene overrepresentation in cellular component category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 1.9 | GO:0030863 | cortical cytoskeleton(GO:0030863) |
| 0.1 | 1.1 | GO:0005732 | small nucleolar ribonucleoprotein complex(GO:0005732) |
| 0.2 | 0.7 | GO:0016600 | flotillin complex(GO:0016600) |
| 0.1 | 0.5 | GO:0061700 | GATOR2 complex(GO:0061700) |
| 0.0 | 0.4 | GO:0035371 | microtubule plus-end(GO:0035371) |
| 0.0 | 0.1 | GO:0019815 | B cell receptor complex(GO:0019815) |
Gene overrepresentation in molecular function category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.2 | 5.4 | GO:0048306 | calcium-dependent protein binding(GO:0048306) |
| 0.8 | 2.4 | GO:0004087 | carbamoyl-phosphate synthase (ammonia) activity(GO:0004087) |
| 0.3 | 1.6 | GO:0016822 | hydrolase activity, acting on acid carbon-carbon bonds(GO:0016822) hydrolase activity, acting on acid carbon-carbon bonds, in ketonic substances(GO:0016823) |
| 0.1 | 1.5 | GO:0003810 | protein-glutamine gamma-glutamyltransferase activity(GO:0003810) |
| 0.0 | 1.4 | GO:0003730 | mRNA 3'-UTR binding(GO:0003730) |
| 0.4 | 1.3 | GO:0001729 | ceramide kinase activity(GO:0001729) |
| 0.0 | 1.3 | GO:0001227 | transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001227) |
| 0.2 | 1.1 | GO:0008379 | thioredoxin peroxidase activity(GO:0008379) |
| 0.1 | 1.1 | GO:0004861 | cyclin-dependent protein serine/threonine kinase inhibitor activity(GO:0004861) |
| 0.0 | 1.1 | GO:0016790 | thiolester hydrolase activity(GO:0016790) |
Gene overrepresentation in curated gene sets: canonical pathways category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 1.0 | PID ALPHA SYNUCLEIN PATHWAY | Alpha-synuclein signaling |
| 0.0 | 1.0 | PID CMYB PATHWAY | C-MYB transcription factor network |
| 0.0 | 0.4 | SIG REGULATION OF THE ACTIN CYTOSKELETON BY RHO GTPASES | Genes related to regulation of the actin cytoskeleton |
Gene overrepresentation in curated gene sets: REACTOME pathways category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 4.0 | REACTOME METABOLISM OF AMINO ACIDS AND DERIVATIVES | Genes involved in Metabolism of amino acids and derivatives |
| 0.1 | 1.1 | REACTOME SLBP DEPENDENT PROCESSING OF REPLICATION DEPENDENT HISTONE PRE MRNAS | Genes involved in SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs |
| 0.0 | 0.3 | REACTOME REGULATION OF SIGNALING BY CBL | Genes involved in Regulation of signaling by CBL |