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PRJNA195909:zebrafish embryo and larva development
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Results for pax2b
Z-value: 2.08
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Transcription factors associated with pax2b
Activity-expression correlation:
| Gene | Promoter | Pearson corr. coef. | P-value | Plot |
|---|---|---|---|---|
| pax2b | dr11_v1_chr12_-_45876387_45876387 | -0.71 | 3.1e-02 | Click! |
| Promoter | Log-likelihood | Transcript | Gene | Gene Info |
|---|---|---|---|---|
| chr12_-_33359052 Show fit | 3.61 |
ENSDART00000135943
|
solute carrier family 16 (monocarboxylate transporter), member 3 |
|
| chr22_-_25612680 Show fit | 3.38 |
ENSDART00000114167
|
si:ch211-12h2.8 |
|
| chr7_+_67699009 Show fit | 2.99 |
ENSDART00000192810
|
zgc:162592 |
|
| chr8_+_52442622 Show fit | 2.91 |
ENSDART00000012758
|
zgc:77112 |
|
| chr7_-_55648336 Show fit | 2.91 |
ENSDART00000147792
ENSDART00000135304 ENSDART00000131923 |
poly(A) binding protein, nuclear 1-like (cytoplasmic) |
|
| chr8_+_23725957 Show fit | 2.84 |
ENSDART00000104346
|
makorin, ring finger protein, 4 |
|
| chr15_-_35126332 Show fit | 2.72 |
ENSDART00000007636
|
zgc:55413 |
|
| chr10_+_16501699 Show fit | 2.55 |
ENSDART00000121864
|
solute carrier family 27 (fatty acid transporter), member 6 |
|
| chr11_-_44801968 Show fit | 2.41 |
ENSDART00000161846
|
microtubule-associated protein 1 light chain 3 gamma |
|
| chr20_+_35445462 Show fit | 2.40 |
ENSDART00000124497
|
tudor domain containing 6 |
Network of associatons between targets according to the STRING database.
First level regulatory network of pax2b
Gene Ontology Analysis
Gene overrepresentation in biological process category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.7 | 7.6 | GO:0030719 | P granule organization(GO:0030719) |
| 0.1 | 4.8 | GO:0007157 | heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0007157) |
| 0.1 | 3.5 | GO:0051170 | nuclear import(GO:0051170) |
| 0.0 | 3.4 | GO:0030837 | negative regulation of actin filament polymerization(GO:0030837) negative regulation of protein polymerization(GO:0032272) |
| 0.3 | 3.3 | GO:1901678 | heme transport(GO:0015886) iron coordination entity transport(GO:1901678) |
| 0.3 | 3.3 | GO:0006685 | sphingomyelin catabolic process(GO:0006685) |
| 0.2 | 3.2 | GO:0032885 | regulation of polysaccharide biosynthetic process(GO:0032885) |
| 0.1 | 3.2 | GO:0006303 | double-strand break repair via nonhomologous end joining(GO:0006303) |
| 0.1 | 3.1 | GO:0030488 | tRNA methylation(GO:0030488) |
| 0.2 | 3.0 | GO:0045747 | positive regulation of Notch signaling pathway(GO:0045747) |
Gene overrepresentation in cellular component category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.1 | 8.9 | GO:0043296 | apical junction complex(GO:0043296) |
| 0.1 | 6.9 | GO:0005802 | trans-Golgi network(GO:0005802) |
| 0.0 | 4.7 | GO:0005912 | adherens junction(GO:0005912) |
| 0.1 | 4.6 | GO:0030496 | midbody(GO:0030496) |
| 0.3 | 4.3 | GO:0000164 | protein phosphatase type 1 complex(GO:0000164) |
| 0.1 | 4.1 | GO:0031901 | early endosome membrane(GO:0031901) |
| 0.0 | 4.0 | GO:0005764 | lysosome(GO:0005764) |
| 0.0 | 3.9 | GO:0005813 | centrosome(GO:0005813) |
| 1.3 | 3.8 | GO:0033391 | chromatoid body(GO:0033391) |
| 0.0 | 3.5 | GO:0000775 | chromosome, centromeric region(GO:0000775) |
Gene overrepresentation in molecular function category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 7.4 | GO:0030695 | GTPase regulator activity(GO:0030695) |
| 0.0 | 6.9 | GO:0004842 | ubiquitin-protein transferase activity(GO:0004842) |
| 0.0 | 4.9 | GO:0004843 | thiol-dependent ubiquitin-specific protease activity(GO:0004843) thiol-dependent ubiquitinyl hydrolase activity(GO:0036459) ubiquitinyl hydrolase activity(GO:0101005) |
| 0.2 | 4.5 | GO:0003887 | DNA-directed DNA polymerase activity(GO:0003887) |
| 0.3 | 4.3 | GO:2001069 | glycogen binding(GO:2001069) |
| 0.0 | 4.1 | GO:0042803 | protein homodimerization activity(GO:0042803) |
| 0.0 | 3.8 | GO:0008017 | microtubule binding(GO:0008017) |
| 0.3 | 3.6 | GO:0015129 | lactate transmembrane transporter activity(GO:0015129) |
| 0.0 | 3.5 | GO:0005085 | guanyl-nucleotide exchange factor activity(GO:0005085) |
| 0.4 | 3.3 | GO:0015232 | heme transporter activity(GO:0015232) |
Gene overrepresentation in curated gene sets: canonical pathways category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.1 | 3.5 | PID CDC42 REG PATHWAY | Regulation of CDC42 activity |
| 0.1 | 2.9 | PID DNA PK PATHWAY | DNA-PK pathway in nonhomologous end joining |
| 0.0 | 2.9 | PID TELOMERASE PATHWAY | Regulation of Telomerase |
| 0.0 | 2.5 | PID P53 DOWNSTREAM PATHWAY | Direct p53 effectors |
| 0.1 | 2.4 | ST ERK1 ERK2 MAPK PATHWAY | ERK1/ERK2 MAPK Pathway |
| 0.1 | 2.1 | PID CIRCADIAN PATHWAY | Circadian rhythm pathway |
| 0.0 | 2.1 | PID TGFBR PATHWAY | TGF-beta receptor signaling |
| 0.0 | 1.6 | PID MYC ACTIV PATHWAY | Validated targets of C-MYC transcriptional activation |
| 0.1 | 1.4 | ST G ALPHA S PATHWAY | G alpha s Pathway |
| 0.1 | 1.4 | PID CERAMIDE PATHWAY | Ceramide signaling pathway |
Gene overrepresentation in curated gene sets: REACTOME pathways category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.2 | 3.6 | REACTOME BILE SALT AND ORGANIC ANION SLC TRANSPORTERS | Genes involved in Bile salt and organic anion SLC transporters |
| 0.1 | 3.6 | REACTOME ION TRANSPORT BY P TYPE ATPASES | Genes involved in Ion transport by P-type ATPases |
| 0.1 | 3.1 | REACTOME ASSOCIATION OF TRIC CCT WITH TARGET PROTEINS DURING BIOSYNTHESIS | Genes involved in Association of TriC/CCT with target proteins during biosynthesis |
| 0.0 | 3.0 | REACTOME ANTIGEN PROCESSING UBIQUITINATION PROTEASOME DEGRADATION | Genes involved in Antigen processing: Ubiquitination & Proteasome degradation |
| 0.2 | 2.8 | REACTOME TRYPTOPHAN CATABOLISM | Genes involved in Tryptophan catabolism |
| 0.1 | 2.7 | REACTOME BMAL1 CLOCK NPAS2 ACTIVATES CIRCADIAN EXPRESSION | Genes involved in BMAL1:CLOCK/NPAS2 Activates Circadian Expression |
| 0.1 | 2.5 | REACTOME PYRIMIDINE METABOLISM | Genes involved in Pyrimidine metabolism |
| 0.1 | 2.4 | REACTOME PROCESSING OF INTRONLESS PRE MRNAS | Genes involved in Processing of Intronless Pre-mRNAs |
| 0.1 | 2.2 | REACTOME TRANSPORT OF VITAMINS NUCLEOSIDES AND RELATED MOLECULES | Genes involved in Transport of vitamins, nucleosides, and related molecules |
| 0.0 | 2.2 | REACTOME SIGNALING BY RHO GTPASES | Genes involved in Signaling by Rho GTPases |