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PRJNA195909:zebrafish embryo and larva development

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Results for pax2a+pax5

Z-value: 1.91

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Transcription factors associated with pax2a+pax5

Gene Symbol Gene ID Gene Info
ENSDARG00000028148 paired box 2a
ENSDARG00000037383 paired box 5

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
pax2adr11_v1_chr13_+_29771463_297714630.891.4e-03Click!
pax5dr11_v1_chr1_+_21731382_217313820.561.2e-01Click!

Activity profile of pax2a+pax5 motif

Sorted Z-values of pax2a+pax5 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr4_+_12031958 4.40 ENSDART00000044154
troponin T2c, cardiac
chr7_+_29952169 3.83 ENSDART00000173540
ENSDART00000173940
ENSDART00000173906
ENSDART00000173772
ENSDART00000173506
ENSDART00000039657
alpha-tropomyosin
chr7_+_29951997 3.35 ENSDART00000173453
alpha-tropomyosin
chr24_-_40731305 3.11 ENSDART00000172073

chr15_+_32711663 3.04 ENSDART00000157854
ENSDART00000167515
periostin, osteoblast specific factor b
chr7_+_29952719 2.96 ENSDART00000173737
alpha-tropomyosin
chr3_-_55139127 2.89 ENSDART00000115324
hemoglobin, alpha embryonic 1.3
chr3_-_55147731 2.58 ENSDART00000155871
ENSDART00000109016
ENSDART00000122904
hemoglobin alpha embryonic-3
chr3_-_55121125 2.44 ENSDART00000125092
hemoglobin, alpha embryonic 1
chr24_-_40668208 2.32 ENSDART00000171543
slow myosin heavy chain 1
chr3_-_46818001 2.10 ENSDART00000166505
ELAV like neuron-specific RNA binding protein 3
chr19_-_21716593 2.00 ENSDART00000155126
zinc finger protein 516
chr20_+_25340814 1.93 ENSDART00000063028
connective tissue growth factor a
chr3_-_61205711 1.78 ENSDART00000055062
parvalbumin 1
chr16_+_23978978 1.72 ENSDART00000058964
ENSDART00000135084
apolipoprotein A-II
chr15_+_32711172 1.69 ENSDART00000163936
ENSDART00000168135
periostin, osteoblast specific factor b
chr7_+_29955368 1.69 ENSDART00000173686
alpha-tropomyosin
chr19_-_42551338 1.69 ENSDART00000162837
zgc:123103
chr9_-_22318511 1.65 ENSDART00000129295
crystallin, gamma M2d2
chr25_+_31405266 1.65 ENSDART00000103395
troponin T type 3a (skeletal, fast)
chr3_-_46817838 1.65 ENSDART00000028610
ELAV like neuron-specific RNA binding protein 3
chr13_+_17672527 1.64 ENSDART00000148269
ENSDART00000137776
catechol-O-methyltransferase domain containing 1
chr3_+_26081343 1.62 ENSDART00000134647
ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 1
chr5_+_36974931 1.60 ENSDART00000193063
gap junction protein delta 1a
chr14_+_50770537 1.60 ENSDART00000158723
synuclein, beta
chr6_+_52790049 1.60 ENSDART00000002571
matrilin 4
chr14_-_36378494 1.56 ENSDART00000058503
glycoprotein M6Aa
chr16_+_23921777 1.54 ENSDART00000163213
apolipoprotein A-IV b, tandem duplicate 3
chr15_-_23342752 1.49 ENSDART00000020425
melanoma cell adhesion molecule b
chr10_+_33171501 1.47 ENSDART00000159666
myosin, light chain 10, regulatory
chr6_+_39360377 1.46 ENSDART00000028260
ENSDART00000151322
zgc:77517
chr21_-_27010796 1.46 ENSDART00000065398
ENSDART00000144342
ENSDART00000126542
protein phosphatase 1, regulatory (inhibitor) subunit 14Ba
chr5_-_67911111 1.42 ENSDART00000051833
GS homeobox 1
chr5_-_36837846 1.37 ENSDART00000032481
creatine kinase, muscle a
chr21_+_21374277 1.37 ENSDART00000079431
reticulon 2b
chr25_+_33192796 1.36 ENSDART00000125892
ENSDART00000121680
ENSDART00000014851
zgc:171719
chr9_-_7539297 1.35 ENSDART00000081550
ENSDART00000081553
desmin a
chr16_-_24518027 1.34 ENSDART00000134120
ENSDART00000143761
cell adhesion molecule 4
chr13_+_39532050 1.33 ENSDART00000019379
MARVEL domain containing 1
chr6_-_24103666 1.30 ENSDART00000164915
scinderin like a
chr24_-_41312459 1.30 ENSDART00000041349
crystallin, gamma N2
chr9_-_22232902 1.29 ENSDART00000101845
crystallin, gamma M2d5
chr19_-_28789404 1.28 ENSDART00000191453
ENSDART00000026992
SRY (sex determining region Y)-box 4a
chr19_+_38422059 1.27 ENSDART00000035093
procollagen, type IX, alpha 2
chr11_+_3254252 1.26 ENSDART00000123568
premelanosome protein a
chr13_-_31452516 1.26 ENSDART00000193268
reticulon 1a
chr24_-_17047918 1.24 ENSDART00000020204
methionine sulfoxide reductase B2
chr18_+_22302635 1.24 ENSDART00000141051
capping protein regulator and myosin 1 linker 2
chr24_+_36636208 1.24 ENSDART00000139211
si:ch73-334d15.4
chr24_+_3963684 1.23 ENSDART00000182959
ENSDART00000185926
ENSDART00000167043
ENSDART00000033394
phosphofructokinase, platelet a
chr19_+_19786117 1.22 ENSDART00000167757
ENSDART00000163546
homeobox A1a
chr21_-_551014 1.22 ENSDART00000099252
vimentin-related 1
chr5_-_28625515 1.21 ENSDART00000190782
ENSDART00000179736
ENSDART00000131729
tenascin C
chr11_-_44543082 1.20 ENSDART00000099568
G protein-coupled receptor 137Bb
chr11_+_30321116 1.17 ENSDART00000187921
ENSDART00000127075
UDP glucuronosyltransferase 1 family, polypeptide B1
chr20_-_17041025 1.16 ENSDART00000063764
si:dkey-5n18.1
chr7_+_31879986 1.16 ENSDART00000138491
myosin binding protein C, cardiac
chr7_-_31441420 1.15 ENSDART00000075398
cartilage intermediate layer protein, nucleotide pyrophosphohydrolase
chr12_-_19103490 1.13 ENSDART00000060561
cold shock domain containing C2, RNA binding a
chr8_+_33035709 1.13 ENSDART00000131660
angiopoietin-like 2b
chr12_+_13256415 1.12 ENSDART00000144542
ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 1, like
chr13_-_29424454 1.12 ENSDART00000026765
solute carrier family 18 (vesicular acetylcholine transporter), member 3a
chr9_-_42989297 1.11 ENSDART00000126871
titin, tandem duplicate 2
chr25_+_6306885 1.10 ENSDART00000142705
ENSDART00000067510
cellular retinoic acid binding protein 1a
chr5_+_38276582 1.09 ENSDART00000158532
guanine nucleotide binding protein (G protein), beta polypeptide 2
chr4_+_5776347 1.09 ENSDART00000076494
notochord granular surface
chr19_-_5364649 1.09 ENSDART00000004812
type I cytokeratin, enveloping layer
chr3_-_61162750 1.07 ENSDART00000055064
parvalbumin 8
chr14_+_46313396 1.07 ENSDART00000047525
crystallin, beta A1, like 1
chr18_-_6634424 1.05 ENSDART00000062423
ENSDART00000179955
troponin I, skeletal, slow c
chr7_+_10610791 1.05 ENSDART00000166064
fumarylacetoacetate hydrolase (fumarylacetoacetase)
chr1_-_29045426 1.04 ENSDART00000019770
glycoprotein M6Ba
chr6_-_14139503 1.03 ENSDART00000089577
calcium channel, voltage-dependent, beta 4b subunit
chr7_-_29625509 1.02 ENSDART00000173723
RAR-related orphan receptor A, paralog b
chr13_-_39947335 1.01 ENSDART00000056996
secreted frizzled-related protein 5
chr22_+_38194151 1.01 ENSDART00000121965
ceruloplasmin
chr3_-_28258462 1.00 ENSDART00000191573
RNA binding fox-1 homolog 1
chr22_-_10459880 1.00 ENSDART00000064801
osteoglycin
chr18_+_9171778 1.00 ENSDART00000101192
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3D
chr11_+_3254524 0.99 ENSDART00000159459
premelanosome protein a
chr2_+_32780138 0.99 ENSDART00000082250
zgc:136930
chr3_+_32526799 0.99 ENSDART00000185755
si:ch73-367p23.2
chr1_+_16127825 0.98 ENSDART00000122503
tumor suppressor candidate 3
chr21_-_28901095 0.98 ENSDART00000180820
CXXC finger protein 5a
chr18_-_6633984 0.98 ENSDART00000185241
troponin I, skeletal, slow c
chr19_-_103289 0.97 ENSDART00000143118
adhesion G protein-coupled receptor B1b
chr9_+_23900703 0.96 ENSDART00000127859
tripartite motif containing 63b
chr3_-_28250722 0.96 ENSDART00000165936
RNA binding fox-1 homolog 1
chr23_-_7799184 0.95 ENSDART00000190946
ENSDART00000165427
myelin transcription factor 1b
chr17_+_26569601 0.94 ENSDART00000153897
neuron-derived neurotrophic factor , like
chr5_+_72108241 0.93 ENSDART00000006606
fatty acid binding protein 1a, liver
chr12_+_17865374 0.92 ENSDART00000169019
transmembrane protein 130
chr18_-_50862939 0.92 ENSDART00000180407

chr8_-_46897734 0.92 ENSDART00000138125
hes family bHLH transcription factor 2, tandem duplicate 2
chr6_-_18992896 0.91 ENSDART00000170228
septin 9b
chr5_-_68916623 0.91 ENSDART00000141917
ENSDART00000109053
ankyrin 1, erythrocytic a
chr16_-_54455573 0.90 ENSDART00000075275
pyruvate kinase L/R
chr10_+_9553935 0.89 ENSDART00000028855
si:ch211-243g18.2
chr7_+_30787903 0.89 ENSDART00000174000
amyloid beta (A4) precursor protein-binding, family A, member 2b
chr13_+_1542493 0.89 ENSDART00000181968

chr16_-_27628994 0.89 ENSDART00000157407
NAC alpha domain containing
chr16_+_32559821 0.88 ENSDART00000093250
POU class 3 homeobox 2b
chr18_+_17418254 0.87 ENSDART00000140191
carboxylesterase 3
chr7_+_20017211 0.87 ENSDART00000100808
B-cell CLL/lymphoma 6, member B
chr24_-_37568359 0.87 ENSDART00000056286
H1 histone family, member 0
chr20_+_20499869 0.86 ENSDART00000036124
SIX homeobox 1b
chr23_+_23119008 0.86 ENSDART00000132418
sterile alpha motif domain containing 11
chr3_-_46817499 0.86 ENSDART00000013717
ELAV like neuron-specific RNA binding protein 3
chr19_+_1184878 0.86 ENSDART00000163539
scratch family zinc finger 1a
chr5_+_43006422 0.85 ENSDART00000009182
aquaporin 3a
chr25_-_225964 0.85 ENSDART00000193424

chr23_+_36653376 0.84 ENSDART00000053189
G protein-coupled receptor 182
chr19_-_3240605 0.84 ENSDART00000105168
si:ch211-133n4.4
chr16_+_5196226 0.83 ENSDART00000189704
SOGA family member 3a
chr13_+_255067 0.82 ENSDART00000102505
forkhead box G1d
chr5_-_55395964 0.82 ENSDART00000145791
prune homolog 2 (Drosophila)
chr7_+_44715224 0.82 ENSDART00000184630
si:dkey-56m19.5
chr12_-_4388704 0.81 ENSDART00000152168
si:ch211-173d10.1
chr3_-_12187245 0.81 ENSDART00000189553
ENSDART00000165131
sarcalumenin
chr25_+_14017609 0.81 ENSDART00000129105
ENSDART00000125733
carbohydrate (keratan sulfate Gal-6) sulfotransferase 1
chr19_+_56351 0.81 ENSDART00000168334
collagen, type XIV, alpha 1b
chr21_+_19445942 0.79 ENSDART00000030887
solute carrier family 45, member 2
chr12_+_36971952 0.79 ENSDART00000125900
heparan sulfate (glucosamine) 3-O-sulfotransferase 3B1b
chr8_-_19904124 0.79 ENSDART00000129193
TraB domain containing 2B
chr4_-_1360495 0.79 ENSDART00000164623
pleiotrophin
chr21_-_40676224 0.79 ENSDART00000162623
aristaless related homeobox b
chr9_-_2594410 0.78 ENSDART00000188306
ENSDART00000164276
sp9 transcription factor
chr18_+_402048 0.78 ENSDART00000166345
glucose-6-phosphate isomerase b
chr2_+_30916188 0.77 ENSDART00000137012
myomesin 1a (skelemin)
chr10_+_158590 0.77 ENSDART00000081982
potassium voltage-gated channel subfamily J member 15
chr1_-_5746030 0.76 ENSDART00000150863
neuropilin 2a
chr16_-_43025885 0.76 ENSDART00000193146
ENSDART00000157302
si:dkey-7j14.5
chr3_-_58650057 0.76 ENSDART00000057640
dehydrogenase/reductase (SDR family) member 7Ca
chr10_-_28761454 0.76 ENSDART00000129400
activated leukocyte cell adhesion molecule a
chr14_-_17068511 0.75 ENSDART00000163766
paired-like homeobox 2bb
chr5_-_55395384 0.75 ENSDART00000147298
ENSDART00000082577
prune homolog 2 (Drosophila)
chr13_-_46421682 0.75 ENSDART00000149602
fibroblast growth factor receptor 2
chr15_+_5923851 0.74 ENSDART00000152520
ENSDART00000145827
ENSDART00000121529
SH3 domain binding glutamate-rich protein
chr6_-_32703317 0.74 ENSDART00000064833
v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog Aa
chr10_+_21730585 0.74 ENSDART00000188576
protocadherin 1 gamma 22
chr10_+_34394454 0.74 ENSDART00000110121
StAR-related lipid transfer (START) domain containing 13a
chr11_+_11201096 0.74 ENSDART00000171916
ENSDART00000171521
ENSDART00000087105
ENSDART00000159603
myomesin 2a
chr11_+_23957440 0.73 ENSDART00000190721
contactin 2
chr16_-_13730152 0.73 ENSDART00000138772
tweety family member 1
chr17_-_32865788 0.73 ENSDART00000077476
prospero homeobox 1a
chr21_+_40106448 0.73 ENSDART00000100166
serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1
chr16_+_28596555 0.73 ENSDART00000046209
ENSDART00000141708
acyl-CoA binding domain containing 7
chr8_+_41281801 0.72 ENSDART00000084439
olfactomedin-like 2A
chr13_+_4405282 0.72 ENSDART00000148280
proline rich 18
chr9_+_307863 0.72 ENSDART00000163474
SH3 and cysteine rich domain 3
chr2_-_9646857 0.72 ENSDART00000056901
zgc:153615
chr8_-_21268303 0.71 ENSDART00000067211
G protein-coupled receptor 37 like 1b
chr11_-_18253111 0.71 ENSDART00000125984
musculoskeletal, embryonic nuclear protein 1b
chr21_+_5129513 0.70 ENSDART00000102572
thrombospondin 4b
chr18_-_46010 0.70 ENSDART00000052641
glycine amidinotransferase (L-arginine:glycine amidinotransferase)
chr8_-_1051438 0.70 ENSDART00000067093
ENSDART00000170737
SET and MYND domain containing 1b
chr1_-_31534089 0.69 ENSDART00000007770
ladybird homeobox 1b
chr10_-_17103651 0.69 ENSDART00000108959
ring finger protein 208
chr3_-_41791178 0.69 ENSDART00000049687
galectin-related inter-fiber protein
chr11_-_35763323 0.69 ENSDART00000026017
basic helix-loop-helix family, member e40
chr21_-_28920245 0.69 ENSDART00000132884
CXXC finger protein 5a
chr4_+_16323970 0.69 ENSDART00000190651

chr9_+_54679221 0.68 ENSDART00000167769
EGF-like-domain, multiple 6
chr5_+_43603794 0.68 ENSDART00000134633
si:dkey-40c11.2
chr10_-_26729930 0.68 ENSDART00000145532
fibroblast growth factor 13b
chr21_-_23746916 0.68 ENSDART00000017229
neural cell adhesion molecule 1a
chr16_-_13921589 0.68 ENSDART00000023543
recoverin 2
chr19_+_31771270 0.68 ENSDART00000147474
stathmin 2b
chr18_-_48530221 0.68 ENSDART00000188134
ENSDART00000142107
potassium inwardly-rectifying channel, subfamily J, member 1a, tandem duplicate 2
chr8_+_39634114 0.67 ENSDART00000144293
musashi RNA-binding protein 1
chr12_+_47909026 0.67 ENSDART00000192472
thymus, brain and testes associated
chr9_-_7683799 0.67 ENSDART00000102713
si:ch73-199e17.1
chr10_-_22803740 0.67 ENSDART00000079469
ENSDART00000187968
ENSDART00000122543
procollagen C-endopeptidase enhancer a
chr23_-_4091009 0.67 ENSDART00000109807

chr14_+_20893065 0.66 ENSDART00000079452
lysozyme g-like 1
chr4_-_17055782 0.66 ENSDART00000134595
SRY (sex determining region Y)-box 5
chr14_+_33722950 0.66 ENSDART00000075312
apelin
chr12_+_45676667 0.66 ENSDART00000016553
si:ch73-111m19.2
chr16_-_28856112 0.66 ENSDART00000078543
synaptotagmin XIb
chr5_-_19394440 0.65 ENSDART00000163771
forkhead box N4
chr23_+_24705424 0.65 ENSDART00000104029
C1q and TNF related 12
chr8_-_31075015 0.65 ENSDART00000010993
solute carrier family 20, member 1a
chr14_-_21219659 0.65 ENSDART00000089867
protein phosphatase 2, regulatory subunit B, gamma b
chr7_-_30177691 0.65 ENSDART00000046689
transmembrane p24 trafficking protein 3
chr24_-_2947393 0.65 ENSDART00000166661
ENSDART00000147110
tubulin, beta 6 class V
chr17_-_26911852 0.64 ENSDART00000045842
regulator of calcineurin 3
chr6_-_13187168 0.64 ENSDART00000193286
ENSDART00000188350
ENSDART00000150036
ENSDART00000149940
ADAM metallopeptidase domain 23a
chr2_+_21982911 0.64 ENSDART00000190722
ENSDART00000044371
ENSDART00000134912
thymocyte selection-associated high mobility group box
chr5_+_65991152 0.64 ENSDART00000097756
lipocalin 15
chr9_+_23665777 0.64 ENSDART00000060905
glycophorin C (Gerbich blood group)
chr9_-_18877597 0.64 ENSDART00000099446
potassium channel tetramerization domain containing 4
chr9_-_7684002 0.64 ENSDART00000016360
si:ch73-199e17.1
chr5_+_27432958 0.63 ENSDART00000124705
histone H1 like
chr16_+_29043813 0.63 ENSDART00000122681
nestin
chr5_+_34407763 0.63 ENSDART00000188849
ENSDART00000145127
laminin, gamma 3
chr16_-_29277164 0.62 ENSDART00000058870
Rh family, B glycoprotein (gene/pseudogene)
chr9_+_34641237 0.62 ENSDART00000133996
short stature homeobox
chr14_+_32022272 0.62 ENSDART00000105760
zic family member 6
chr21_-_10773344 0.62 ENSDART00000063244
gastrin-releasing peptide
chr8_-_23416362 0.62 ENSDART00000063005
G protein-coupled receptor 173

Network of associatons between targets according to the STRING database.

First level regulatory network of pax2a+pax5

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.8 2.3 GO:0097435 fibril organization(GO:0097435)
0.5 0.5 GO:0060055 angiogenesis involved in wound healing(GO:0060055)
0.4 1.3 GO:0006601 creatine metabolic process(GO:0006600) creatine biosynthetic process(GO:0006601)
0.4 1.6 GO:0031448 regulation of twitch skeletal muscle contraction(GO:0014724) regulation of fast-twitch skeletal muscle fiber contraction(GO:0031446) positive regulation of fast-twitch skeletal muscle fiber contraction(GO:0031448) negative regulation of striated muscle contraction(GO:0045988) relaxation of skeletal muscle(GO:0090076)
0.4 1.2 GO:0014814 regulation of synaptic growth at neuromuscular junction(GO:0008582) axon regeneration at neuromuscular junction(GO:0014814) positive regulation of synaptic growth at neuromuscular junction(GO:0045887)
0.4 1.2 GO:0045671 negative regulation of osteoclast differentiation(GO:0045671)
0.4 1.1 GO:0042908 xenobiotic transport(GO:0042908)
0.4 0.7 GO:0014808 regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum(GO:0010880) release of sequestered calcium ion into cytosol by sarcoplasmic reticulum(GO:0014808) sarcoplasmic reticulum calcium ion transport(GO:0070296) calcium ion transport from endoplasmic reticulum to cytosol(GO:1903514)
0.3 1.0 GO:1903792 regulation of neurotransmitter uptake(GO:0051580) negative regulation of anion transport(GO:1903792)
0.3 1.4 GO:0010882 regulation of cardiac muscle contraction by calcium ion signaling(GO:0010882)
0.3 2.3 GO:0014721 voluntary skeletal muscle contraction(GO:0003010) twitch skeletal muscle contraction(GO:0014721) slow-twitch skeletal muscle fiber contraction(GO:0031444)
0.3 1.2 GO:0030091 protein repair(GO:0030091)
0.3 1.2 GO:0061549 sympathetic ganglion development(GO:0061549)
0.3 0.9 GO:0021960 anterior commissure morphogenesis(GO:0021960)
0.3 0.9 GO:0097623 potassium ion export(GO:0071435) potassium ion export across plasma membrane(GO:0097623)
0.3 0.9 GO:0002074 extraocular skeletal muscle development(GO:0002074)
0.3 1.0 GO:0061031 endodermal digestive tract morphogenesis(GO:0061031)
0.2 1.0 GO:0035989 tendon development(GO:0035989)
0.2 4.4 GO:0016203 muscle attachment(GO:0016203)
0.2 0.7 GO:0048682 axon extension involved in regeneration(GO:0048677) sprouting of injured axon(GO:0048682)
0.2 1.0 GO:0090386 phagosome maturation involved in apoptotic cell clearance(GO:0090386) phagolysosome assembly involved in apoptotic cell clearance(GO:0090387)
0.2 5.0 GO:0015671 oxygen transport(GO:0015671)
0.2 1.0 GO:0003322 pancreatic A cell development(GO:0003322)
0.2 1.2 GO:0003210 cardiac atrium formation(GO:0003210)
0.2 0.7 GO:0021961 posterior commissure morphogenesis(GO:0021961)
0.2 1.3 GO:0003207 cardiac chamber formation(GO:0003207)
0.2 0.7 GO:0016998 cell wall macromolecule catabolic process(GO:0016998)
0.2 1.1 GO:0007508 larval development(GO:0002164) larval heart development(GO:0007508)
0.2 0.6 GO:0019557 formate metabolic process(GO:0015942) histidine catabolic process to glutamate and formamide(GO:0019556) histidine catabolic process to glutamate and formate(GO:0019557) formamide metabolic process(GO:0043606)
0.2 1.4 GO:0033278 cell proliferation in midbrain(GO:0033278)
0.2 0.6 GO:0098528 skeletal muscle fiber differentiation(GO:0098528)
0.2 0.5 GO:0097264 self proteolysis(GO:0097264)
0.2 1.0 GO:0006572 tyrosine catabolic process(GO:0006572)
0.2 0.5 GO:1900745 positive regulation of p38MAPK cascade(GO:1900745)
0.2 1.0 GO:0055016 hypochord development(GO:0055016)
0.2 1.8 GO:0006735 glucose catabolic process(GO:0006007) NADH regeneration(GO:0006735) glycolytic process through fructose-6-phosphate(GO:0061615) glycolytic process through glucose-6-phosphate(GO:0061620) canonical glycolysis(GO:0061621) glucose catabolic process to pyruvate(GO:0061718)
0.2 2.1 GO:0050936 xanthophore differentiation(GO:0050936)
0.2 0.6 GO:1901881 positive regulation of protein depolymerization(GO:1901881)
0.2 0.8 GO:0030326 embryonic limb morphogenesis(GO:0030326)
0.2 0.5 GO:0010430 fatty acid omega-oxidation(GO:0010430)
0.2 1.2 GO:2000253 positive regulation of feeding behavior(GO:2000253)
0.2 6.6 GO:0006937 regulation of muscle contraction(GO:0006937)
0.1 1.6 GO:0006797 polyphosphate metabolic process(GO:0006797) polyphosphate catabolic process(GO:0006798)
0.1 2.3 GO:0048769 sarcomerogenesis(GO:0048769)
0.1 0.7 GO:0035988 chondrocyte proliferation(GO:0035988)
0.1 0.6 GO:0007638 mechanosensory behavior(GO:0007638)
0.1 0.7 GO:0098974 postsynaptic actin cytoskeleton organization(GO:0098974)
0.1 0.4 GO:0090075 relaxation of muscle(GO:0090075)
0.1 16.1 GO:0006936 muscle contraction(GO:0006936)
0.1 0.9 GO:0060221 retinal rod cell differentiation(GO:0060221)
0.1 0.6 GO:0097272 ammonia homeostasis(GO:0097272)
0.1 0.7 GO:0090134 mesendoderm migration(GO:0090133) cell migration involved in mesendoderm migration(GO:0090134)
0.1 0.4 GO:0034382 chylomicron remnant clearance(GO:0034382) triglyceride-rich lipoprotein particle clearance(GO:0071830) intermediate-density lipoprotein particle clearance(GO:0071831)
0.1 0.5 GO:0046324 regulation of glucose import(GO:0046324)
0.1 0.9 GO:0045475 locomotor rhythm(GO:0045475)
0.1 0.7 GO:0035332 positive regulation of hippo signaling(GO:0035332)
0.1 0.7 GO:0090104 pancreatic epsilon cell differentiation(GO:0090104)
0.1 0.5 GO:0051503 intracellular nucleoside transport(GO:0015859) purine nucleoside transmembrane transport(GO:0015860) purine nucleotide transport(GO:0015865) ATP transport(GO:0015867) purine ribonucleotide transport(GO:0015868) adenine nucleotide transport(GO:0051503) mitochondrial ATP transmembrane transport(GO:1990544)
0.1 0.7 GO:0035881 amacrine cell differentiation(GO:0035881)
0.1 0.5 GO:0014005 microglia development(GO:0014005)
0.1 1.1 GO:0060612 adipose tissue development(GO:0060612)
0.1 0.7 GO:0001937 negative regulation of endothelial cell proliferation(GO:0001937)
0.1 0.3 GO:1902746 negative regulation of epithelial cell differentiation(GO:0030857) regulation of lens fiber cell differentiation(GO:1902746)
0.1 1.4 GO:0046314 phosphagen metabolic process(GO:0006599) phosphocreatine metabolic process(GO:0006603) phosphagen biosynthetic process(GO:0042396) phosphocreatine biosynthetic process(GO:0046314)
0.1 0.4 GO:0061032 pericardium development(GO:0060039) visceral serous pericardium development(GO:0061032)
0.1 0.5 GO:0032656 interleukin-13 production(GO:0032616) regulation of interleukin-13 production(GO:0032656)
0.1 0.4 GO:0070166 enamel mineralization(GO:0070166)
0.1 0.2 GO:0090259 regulation of retinal ganglion cell axon guidance(GO:0090259)
0.1 0.5 GO:0051145 smooth muscle cell differentiation(GO:0051145)
0.1 0.3 GO:0036336 dendritic cell chemotaxis(GO:0002407) dendritic cell migration(GO:0036336)
0.1 0.8 GO:0048635 negative regulation of muscle organ development(GO:0048635)
0.1 0.5 GO:0045737 positive regulation of cyclin-dependent protein serine/threonine kinase activity(GO:0045737) positive regulation of cyclin-dependent protein kinase activity(GO:1904031)
0.1 0.4 GO:1902514 calcium ion transmembrane transport via high voltage-gated calcium channel(GO:0061577) regulation of calcium ion transmembrane transport via high voltage-gated calcium channel(GO:1902514)
0.1 0.9 GO:0070262 peptidyl-serine dephosphorylation(GO:0070262)
0.1 1.1 GO:0060035 notochord cell development(GO:0060035)
0.1 1.2 GO:0045880 positive regulation of smoothened signaling pathway(GO:0045880)
0.1 0.4 GO:2000561 negative regulation of interferon-gamma production(GO:0032689) CD4-positive, alpha-beta T cell proliferation(GO:0035739) regulation of CD4-positive, alpha-beta T cell proliferation(GO:2000561) negative regulation of CD4-positive, alpha-beta T cell proliferation(GO:2000562)
0.1 0.5 GO:0001955 blood vessel maturation(GO:0001955)
0.1 0.4 GO:0010133 proline catabolic process to glutamate(GO:0010133)
0.1 0.2 GO:0072344 rescue of stalled ribosome(GO:0072344)
0.1 1.3 GO:0006228 UTP biosynthetic process(GO:0006228) UTP metabolic process(GO:0046051)
0.1 0.3 GO:0032534 regulation of microvillus organization(GO:0032530) regulation of microvillus assembly(GO:0032534)
0.1 0.3 GO:2000171 negative regulation of dendrite development(GO:2000171)
0.1 0.4 GO:0021534 cell proliferation in hindbrain(GO:0021534)
0.1 0.6 GO:0032986 nucleosome disassembly(GO:0006337) chromatin disassembly(GO:0031498) protein-DNA complex disassembly(GO:0032986)
0.1 1.0 GO:0045747 positive regulation of Notch signaling pathway(GO:0045747)
0.1 0.3 GO:0030205 dermatan sulfate metabolic process(GO:0030205)
0.1 0.2 GO:0000711 meiotic DNA repair synthesis(GO:0000711)
0.1 0.7 GO:0036368 cone photoresponse recovery(GO:0036368)
0.1 0.1 GO:0061217 regulation of morphogenesis of a branching structure(GO:0060688) positive regulation of mesonephros development(GO:0061213) regulation of mesonephros development(GO:0061217) regulation of kidney development(GO:0090183) positive regulation of kidney development(GO:0090184) regulation of branching involved in ureteric bud morphogenesis(GO:0090189) positive regulation of branching involved in ureteric bud morphogenesis(GO:0090190)
0.1 0.6 GO:0035493 SNARE complex assembly(GO:0035493)
0.1 0.5 GO:0021588 cerebellum formation(GO:0021588)
0.1 1.0 GO:0015693 magnesium ion transport(GO:0015693)
0.1 0.3 GO:0003209 cardiac atrium morphogenesis(GO:0003209)
0.1 0.5 GO:0048172 regulation of short-term neuronal synaptic plasticity(GO:0048172)
0.1 2.1 GO:0031103 axon regeneration(GO:0031103)
0.1 1.4 GO:0071542 dopaminergic neuron differentiation(GO:0071542)
0.1 0.6 GO:0015810 acidic amino acid transport(GO:0015800) aspartate transport(GO:0015810) L-glutamate transport(GO:0015813) malate-aspartate shuttle(GO:0043490)
0.1 1.7 GO:0051014 actin filament severing(GO:0051014)
0.1 0.2 GO:0002468 dendritic cell antigen processing and presentation(GO:0002468)
0.1 0.2 GO:1901673 regulation of mitotic spindle assembly(GO:1901673)
0.1 0.1 GO:0006884 cell volume homeostasis(GO:0006884)
0.1 0.4 GO:0090243 fibroblast growth factor receptor signaling pathway involved in somitogenesis(GO:0090243)
0.1 0.4 GO:0098815 postsynaptic density assembly(GO:0097107) modulation of excitatory postsynaptic potential(GO:0098815) positive regulation of excitatory postsynaptic potential(GO:2000463)
0.1 0.2 GO:0006740 NADPH regeneration(GO:0006740)
0.1 0.3 GO:0035479 angioblast cell migration from lateral mesoderm to midline(GO:0035479)
0.1 0.8 GO:0001964 startle response(GO:0001964)
0.1 0.8 GO:0006044 N-acetylglucosamine metabolic process(GO:0006044)
0.0 0.6 GO:0048899 anterior lateral line development(GO:0048899)
0.0 0.7 GO:1905150 regulation of voltage-gated sodium channel activity(GO:1905150)
0.0 0.5 GO:0061001 regulation of dendritic spine morphogenesis(GO:0061001)
0.0 0.1 GO:1901006 ubiquinone-6 metabolic process(GO:1901004) ubiquinone-6 biosynthetic process(GO:1901006)
0.0 1.0 GO:0006825 copper ion transport(GO:0006825)
0.0 0.0 GO:0038180 nerve growth factor signaling pathway(GO:0038180)
0.0 0.5 GO:1904071 presynaptic active zone assembly(GO:1904071)
0.0 0.3 GO:0097241 hematopoietic stem cell migration to bone marrow(GO:0097241)
0.0 0.8 GO:0030947 regulation of vascular endothelial growth factor receptor signaling pathway(GO:0030947)
0.0 1.5 GO:0072015 glomerular visceral epithelial cell development(GO:0072015) glomerular epithelial cell development(GO:0072310)
0.0 0.9 GO:0045879 negative regulation of smoothened signaling pathway(GO:0045879)
0.0 0.5 GO:0050907 detection of chemical stimulus involved in sensory perception(GO:0050907)
0.0 0.2 GO:0010447 response to acidic pH(GO:0010447)
0.0 0.8 GO:0036444 calcium ion transmembrane import into mitochondrion(GO:0036444)
0.0 0.1 GO:0006656 phosphatidylcholine biosynthetic process(GO:0006656)
0.0 1.1 GO:0043049 otic placode formation(GO:0043049)
0.0 0.5 GO:0034497 protein localization to pre-autophagosomal structure(GO:0034497)
0.0 0.4 GO:0036060 filtration diaphragm assembly(GO:0036058) slit diaphragm assembly(GO:0036060)
0.0 0.7 GO:1903672 positive regulation of sprouting angiogenesis(GO:1903672)
0.0 0.2 GO:0060832 oocyte animal/vegetal axis specification(GO:0060832)
0.0 0.2 GO:0032488 Cdc42 protein signal transduction(GO:0032488)
0.0 4.8 GO:0002088 lens development in camera-type eye(GO:0002088)
0.0 0.1 GO:0048890 lateral line ganglion development(GO:0048890) posterior lateral line ganglion development(GO:0048917)
0.0 0.4 GO:0071300 cellular response to retinoic acid(GO:0071300)
0.0 2.9 GO:0055113 epiboly involved in gastrulation with mouth forming second(GO:0055113)
0.0 0.3 GO:0060386 synapse assembly involved in innervation(GO:0060386)
0.0 1.3 GO:0016339 calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0016339)
0.0 0.3 GO:0006621 protein retention in ER lumen(GO:0006621)
0.0 0.2 GO:0010269 response to selenium ion(GO:0010269)
0.0 0.4 GO:0030011 maintenance of cell polarity(GO:0030011)
0.0 0.1 GO:0015893 folic acid transport(GO:0015884) drug transport(GO:0015893) methotrexate transport(GO:0051958) reduced folate transmembrane transport(GO:0098838)
0.0 0.8 GO:0048791 calcium ion-regulated exocytosis of neurotransmitter(GO:0048791)
0.0 0.9 GO:0001649 osteoblast differentiation(GO:0001649)
0.0 0.7 GO:0021884 forebrain neuron development(GO:0021884)
0.0 0.2 GO:0007603 phototransduction, visible light(GO:0007603) light absorption(GO:0016037)
0.0 0.8 GO:0042541 hemoglobin biosynthetic process(GO:0042541)
0.0 2.0 GO:0007416 synapse assembly(GO:0007416)
0.0 0.3 GO:0097374 sensory neuron axon guidance(GO:0097374)
0.0 0.8 GO:0030497 fatty acid elongation(GO:0030497)
0.0 0.6 GO:0071436 cellular potassium ion homeostasis(GO:0030007) sodium ion export from cell(GO:0036376) sodium ion export(GO:0071436)
0.0 0.4 GO:0048512 rhythmic behavior(GO:0007622) circadian behavior(GO:0048512)
0.0 0.7 GO:0051156 glucose 6-phosphate metabolic process(GO:0051156)
0.0 0.1 GO:0015695 organic cation transport(GO:0015695)
0.0 0.5 GO:0035970 peptidyl-threonine dephosphorylation(GO:0035970)
0.0 0.1 GO:0070221 sulfide oxidation(GO:0019418) sulfide oxidation, using sulfide:quinone oxidoreductase(GO:0070221)
0.0 0.1 GO:0090161 Golgi ribbon formation(GO:0090161)
0.0 0.2 GO:0030916 otic vesicle formation(GO:0030916)
0.0 0.2 GO:0007197 adenylate cyclase-inhibiting G-protein coupled acetylcholine receptor signaling pathway(GO:0007197)
0.0 0.2 GO:2001286 caveolin-mediated endocytosis(GO:0072584) negative regulation of clathrin-mediated endocytosis(GO:1900186) regulation of caveolin-mediated endocytosis(GO:2001286) negative regulation of caveolin-mediated endocytosis(GO:2001287)
0.0 0.2 GO:0051893 cell-substrate adherens junction assembly(GO:0007045) focal adhesion assembly(GO:0048041) regulation of focal adhesion assembly(GO:0051893) regulation of cell-substrate junction assembly(GO:0090109)
0.0 0.1 GO:0046168 NADH oxidation(GO:0006116) glycerol-3-phosphate catabolic process(GO:0046168)
0.0 0.5 GO:0036092 phosphatidylinositol-3-phosphate biosynthetic process(GO:0036092)
0.0 0.2 GO:0021634 optic nerve formation(GO:0021634)
0.0 0.3 GO:0060294 cilium movement involved in cell motility(GO:0060294)
0.0 0.5 GO:0002574 thrombocyte differentiation(GO:0002574)
0.0 0.4 GO:0042476 odontogenesis(GO:0042476)
0.0 0.1 GO:0046677 response to antibiotic(GO:0046677)
0.0 0.4 GO:0018057 peptidyl-lysine oxidation(GO:0018057)
0.0 0.3 GO:0071501 response to sterol depletion(GO:0006991) SREBP signaling pathway(GO:0032933) cellular response to sterol depletion(GO:0071501)
0.0 0.1 GO:0006864 pyrimidine nucleotide transport(GO:0006864) mitochondrial pyrimidine nucleotide import(GO:1990519)
0.0 0.1 GO:0034498 early endosome to Golgi transport(GO:0034498)
0.0 0.1 GO:0003321 positive regulation of heart rate by epinephrine-norepinephrine(GO:0001996) positive regulation of blood pressure by epinephrine-norepinephrine(GO:0003321) positive regulation of heart rate(GO:0010460)
0.0 0.1 GO:0010799 regulation of peptidyl-threonine phosphorylation(GO:0010799) negative regulation of peptidyl-threonine phosphorylation(GO:0010801)
0.0 0.1 GO:0018160 peptidyl-pyrromethane cofactor linkage(GO:0018160)
0.0 0.5 GO:0006491 N-glycan processing(GO:0006491)
0.0 1.0 GO:0071277 cellular response to calcium ion(GO:0071277)
0.0 0.7 GO:0050773 regulation of dendrite development(GO:0050773)
0.0 0.4 GO:0018149 peptide cross-linking(GO:0018149)
0.0 0.4 GO:0033138 positive regulation of peptidyl-serine phosphorylation(GO:0033138)
0.0 0.4 GO:0007634 optokinetic behavior(GO:0007634)
0.0 1.1 GO:0048484 enteric nervous system development(GO:0048484)
0.0 0.1 GO:0010874 regulation of cholesterol efflux(GO:0010874)
0.0 0.4 GO:0006120 mitochondrial electron transport, NADH to ubiquinone(GO:0006120)
0.0 0.4 GO:0000463 maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000463)
0.0 0.3 GO:0019433 triglyceride catabolic process(GO:0019433)
0.0 0.4 GO:0046033 AMP metabolic process(GO:0046033)
0.0 0.1 GO:0015015 heparan sulfate proteoglycan biosynthetic process, enzymatic modification(GO:0015015)
0.0 0.1 GO:0032732 positive regulation of interleukin-1 production(GO:0032732)
0.0 0.4 GO:0030032 lamellipodium assembly(GO:0030032) lamellipodium organization(GO:0097581)
0.0 0.8 GO:0007019 microtubule depolymerization(GO:0007019)
0.0 0.2 GO:0070816 phosphorylation of RNA polymerase II C-terminal domain(GO:0070816)
0.0 0.1 GO:0017186 peptidyl-pyroglutamic acid biosynthetic process, using glutaminyl-peptide cyclotransferase(GO:0017186) peptidyl-glutamine modification(GO:0018199)
0.0 0.1 GO:0006183 GTP biosynthetic process(GO:0006183)
0.0 0.7 GO:0006096 glycolytic process(GO:0006096)
0.0 0.4 GO:0001885 endothelial cell development(GO:0001885)
0.0 0.2 GO:0060416 growth hormone receptor signaling pathway(GO:0060396) response to growth hormone(GO:0060416) cellular response to growth hormone stimulus(GO:0071378)
0.0 0.3 GO:0009134 nucleoside diphosphate catabolic process(GO:0009134)
0.0 0.1 GO:0042989 sequestering of actin monomers(GO:0042989)
0.0 0.3 GO:0032438 melanosome organization(GO:0032438)
0.0 0.2 GO:0006165 nucleoside diphosphate phosphorylation(GO:0006165)
0.0 0.1 GO:0051659 maintenance of mitochondrion location(GO:0051659)
0.0 0.8 GO:0030318 melanocyte differentiation(GO:0030318)
0.0 1.5 GO:0000381 regulation of alternative mRNA splicing, via spliceosome(GO:0000381)
0.0 1.3 GO:0042552 myelination(GO:0042552)
0.0 0.1 GO:0034334 adherens junction maintenance(GO:0034334)
0.0 0.5 GO:0045746 negative regulation of Notch signaling pathway(GO:0045746)
0.0 1.3 GO:0006612 protein targeting to membrane(GO:0006612)
0.0 0.1 GO:0006700 C21-steroid hormone biosynthetic process(GO:0006700)
0.0 0.2 GO:0060012 synaptic transmission, glycinergic(GO:0060012)
0.0 0.5 GO:0030282 bone mineralization(GO:0030282)
0.0 0.9 GO:1990573 potassium ion import across plasma membrane(GO:1990573)
0.0 0.1 GO:0046487 glyoxylate metabolic process(GO:0046487)
0.0 0.2 GO:0000303 response to superoxide(GO:0000303) response to oxygen radical(GO:0000305) removal of superoxide radicals(GO:0019430) cellular response to oxygen radical(GO:0071450) cellular response to superoxide(GO:0071451) cellular oxidant detoxification(GO:0098869) cellular detoxification(GO:1990748)
0.0 0.2 GO:0001992 regulation of systemic arterial blood pressure by vasopressin(GO:0001992)
0.0 0.4 GO:0007214 gamma-aminobutyric acid signaling pathway(GO:0007214)
0.0 0.2 GO:0070212 protein poly-ADP-ribosylation(GO:0070212)
0.0 0.8 GO:0050852 T cell receptor signaling pathway(GO:0050852)
0.0 0.5 GO:0060840 artery development(GO:0060840)
0.0 0.3 GO:0050679 positive regulation of epithelial cell proliferation(GO:0050679)
0.0 1.5 GO:0002040 sprouting angiogenesis(GO:0002040)
0.0 0.5 GO:0042149 cellular response to glucose starvation(GO:0042149)
0.0 3.9 GO:0050767 regulation of neurogenesis(GO:0050767)
0.0 1.2 GO:0010951 negative regulation of endopeptidase activity(GO:0010951)
0.0 0.7 GO:0007193 adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway(GO:0007193)
0.0 0.3 GO:0006516 glycoprotein catabolic process(GO:0006516)
0.0 0.2 GO:0060088 auditory receptor cell stereocilium organization(GO:0060088)
0.0 0.5 GO:0051588 regulation of neurotransmitter transport(GO:0051588)
0.0 0.2 GO:0001574 ganglioside biosynthetic process(GO:0001574)
0.0 0.1 GO:0098926 postsynaptic signal transduction(GO:0098926)
0.0 0.0 GO:0002093 auditory receptor cell morphogenesis(GO:0002093)
0.0 0.2 GO:0032958 inositol phosphate biosynthetic process(GO:0032958)
0.0 0.1 GO:0002949 tRNA threonylcarbamoyladenosine modification(GO:0002949)
0.0 0.1 GO:0031102 neuron projection regeneration(GO:0031102)
0.0 0.7 GO:0021782 glial cell development(GO:0021782)
0.0 2.9 GO:0030198 extracellular matrix organization(GO:0030198) extracellular structure organization(GO:0043062)
0.0 0.2 GO:0006208 pyrimidine nucleobase catabolic process(GO:0006208)
0.0 0.0 GO:0034138 toll-like receptor 3 signaling pathway(GO:0034138)
0.0 0.1 GO:0003261 cardiac muscle progenitor cell migration to the midline involved in heart field formation(GO:0003261)
0.0 0.4 GO:0006749 glutathione metabolic process(GO:0006749)
0.0 0.1 GO:0051898 negative regulation of protein kinase B signaling(GO:0051898)
0.0 0.1 GO:0006646 phosphatidylethanolamine biosynthetic process(GO:0006646)
0.0 0.1 GO:2000054 negative regulation of Wnt signaling pathway involved in dorsal/ventral axis specification(GO:2000054)
0.0 0.6 GO:0021510 spinal cord development(GO:0021510)
0.0 0.0 GO:0018158 protein oxidation(GO:0018158)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 5.0 GO:0031838 haptoglobin-hemoglobin complex(GO:0031838)
0.4 1.6 GO:0031673 H zone(GO:0031673)
0.2 8.6 GO:0005861 troponin complex(GO:0005861)
0.2 1.8 GO:0005945 6-phosphofructokinase complex(GO:0005945)
0.2 0.6 GO:0061702 inflammasome complex(GO:0061702)
0.2 3.2 GO:0031430 M band(GO:0031430)
0.1 0.9 GO:0005854 nascent polypeptide-associated complex(GO:0005854)
0.1 0.7 GO:0042584 chromaffin granule membrane(GO:0042584)
0.1 1.7 GO:0044295 axonal growth cone(GO:0044295)
0.1 1.4 GO:0030122 AP-2 adaptor complex(GO:0030122)
0.1 1.6 GO:0005922 connexon complex(GO:0005922)
0.1 0.7 GO:0005784 Sec61 translocon complex(GO:0005784)
0.1 0.3 GO:0060077 inhibitory synapse(GO:0060077)
0.1 0.7 GO:0005790 smooth endoplasmic reticulum(GO:0005790)
0.1 12.0 GO:0005884 actin filament(GO:0005884)
0.1 1.6 GO:0033017 sarcoplasmic reticulum membrane(GO:0033017)
0.1 0.4 GO:0034363 intermediate-density lipoprotein particle(GO:0034363)
0.1 0.7 GO:0000923 equatorial microtubule organizing center(GO:0000923)
0.1 0.6 GO:0031672 A band(GO:0031672)
0.1 8.9 GO:0005882 intermediate filament(GO:0005882)
0.1 1.2 GO:0030315 T-tubule(GO:0030315)
0.1 0.2 GO:1990072 TRAPPIII protein complex(GO:1990072)
0.1 2.7 GO:0048770 melanosome(GO:0042470) pigment granule(GO:0048770)
0.1 1.0 GO:0008250 oligosaccharyltransferase complex(GO:0008250)
0.1 0.5 GO:0034045 pre-autophagosomal structure membrane(GO:0034045)
0.1 0.9 GO:0030663 COPI-coated vesicle membrane(GO:0030663)
0.1 0.4 GO:0031045 dense core granule(GO:0031045)
0.1 1.0 GO:0044298 neuronal cell body membrane(GO:0032809) cell body membrane(GO:0044298)
0.1 2.1 GO:0043679 axon terminus(GO:0043679)
0.1 0.2 GO:0070195 growth hormone receptor complex(GO:0070195)
0.0 0.2 GO:0016460 myosin II complex(GO:0016460)
0.0 0.5 GO:0098982 GABA-ergic synapse(GO:0098982)
0.0 0.5 GO:0061617 MICOS complex(GO:0061617)
0.0 0.2 GO:0097224 sperm connecting piece(GO:0097224)
0.0 0.3 GO:0000126 transcription factor TFIIIB complex(GO:0000126)
0.0 0.1 GO:0034709 methylosome(GO:0034709)
0.0 2.3 GO:0005834 heterotrimeric G-protein complex(GO:0005834)
0.0 0.4 GO:1990246 uniplex complex(GO:1990246)
0.0 0.8 GO:0001518 voltage-gated sodium channel complex(GO:0001518) sodium channel complex(GO:0034706)
0.0 0.1 GO:0032839 dendrite cytoplasm(GO:0032839)
0.0 0.2 GO:0000439 core TFIIH complex(GO:0000439)
0.0 0.5 GO:0071564 npBAF complex(GO:0071564)
0.0 0.7 GO:0016528 sarcoplasm(GO:0016528) sarcoplasmic reticulum(GO:0016529)
0.0 0.2 GO:0019814 immunoglobulin complex(GO:0019814)
0.0 0.4 GO:0030904 retromer complex(GO:0030904)
0.0 0.5 GO:0032591 dendritic spine membrane(GO:0032591)
0.0 3.5 GO:0043197 dendritic spine(GO:0043197) neuron spine(GO:0044309)
0.0 3.0 GO:0005604 basement membrane(GO:0005604)
0.0 0.2 GO:0000172 ribonuclease MRP complex(GO:0000172)
0.0 0.4 GO:0005892 acetylcholine-gated channel complex(GO:0005892)
0.0 2.1 GO:0005581 collagen trimer(GO:0005581)
0.0 0.3 GO:0030132 clathrin coat of coated pit(GO:0030132)
0.0 0.2 GO:0030891 VCB complex(GO:0030891)
0.0 0.3 GO:0034364 high-density lipoprotein particle(GO:0034364)
0.0 0.2 GO:0031526 brush border membrane(GO:0031526)
0.0 6.5 GO:0031012 extracellular matrix(GO:0031012)
0.0 0.4 GO:0002178 palmitoyltransferase complex(GO:0002178)
0.0 0.3 GO:0005742 mitochondrial outer membrane translocase complex(GO:0005742)
0.0 1.1 GO:0005747 mitochondrial respiratory chain complex I(GO:0005747) NADH dehydrogenase complex(GO:0030964) respiratory chain complex I(GO:0045271)
0.0 0.1 GO:0001405 presequence translocase-associated import motor(GO:0001405)
0.0 0.9 GO:0032156 septin ring(GO:0005940) septin complex(GO:0031105) septin cytoskeleton(GO:0032156)
0.0 0.1 GO:0034272 phosphatidylinositol 3-kinase complex, class III, type I(GO:0034271) phosphatidylinositol 3-kinase complex, class III, type II(GO:0034272)
0.0 1.3 GO:0034704 voltage-gated calcium channel complex(GO:0005891) calcium channel complex(GO:0034704)
0.0 0.3 GO:0031307 integral component of mitochondrial outer membrane(GO:0031307)
0.0 0.4 GO:0034992 microtubule organizing center attachment site(GO:0034992) LINC complex(GO:0034993)
0.0 0.8 GO:0030426 growth cone(GO:0030426)
0.0 0.4 GO:0009925 basal plasma membrane(GO:0009925)
0.0 0.1 GO:0009331 glycerol-3-phosphate dehydrogenase complex(GO:0009331)
0.0 0.1 GO:0005921 gap junction(GO:0005921)
0.0 0.9 GO:0022627 cytosolic small ribosomal subunit(GO:0022627)
0.0 1.5 GO:0045121 membrane raft(GO:0045121) membrane microdomain(GO:0098857)
0.0 0.3 GO:0036126 sperm flagellum(GO:0036126)
0.0 0.9 GO:0030863 cortical cytoskeleton(GO:0030863)
0.0 0.2 GO:0016602 CCAAT-binding factor complex(GO:0016602)
0.0 0.3 GO:0046930 pore complex(GO:0046930)
0.0 0.3 GO:0090545 NuRD complex(GO:0016581) CHD-type complex(GO:0090545)
0.0 14.4 GO:0005615 extracellular space(GO:0005615)
0.0 0.4 GO:0000159 protein phosphatase type 2A complex(GO:0000159)
0.0 0.1 GO:0002142 stereocilia coupling link(GO:0002139) stereocilia ankle link(GO:0002141) stereocilia ankle link complex(GO:0002142) stereocilium tip(GO:0032426)
0.0 0.5 GO:0031305 integral component of mitochondrial inner membrane(GO:0031305)
0.0 0.7 GO:0030018 Z disc(GO:0030018)
0.0 0.8 GO:0005814 centriole(GO:0005814)
0.0 0.6 GO:0034707 chloride channel complex(GO:0034707)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 6.0 GO:0031013 troponin C binding(GO:0030172) troponin I binding(GO:0031013)
0.5 1.6 GO:1903136 cuprous ion binding(GO:1903136)
0.4 5.0 GO:0031720 haptoglobin binding(GO:0031720)
0.3 1.0 GO:0031704 apelin receptor binding(GO:0031704)
0.3 1.2 GO:0033745 L-methionine-(R)-S-oxide reductase activity(GO:0033745)
0.3 0.9 GO:0004771 sterol esterase activity(GO:0004771)
0.3 1.1 GO:0031782 type 3 melanocortin receptor binding(GO:0031781) type 4 melanocortin receptor binding(GO:0031782)
0.3 1.3 GO:0016822 hydrolase activity, acting on acid carbon-carbon bonds(GO:0016822) hydrolase activity, acting on acid carbon-carbon bonds, in ketonic substances(GO:0016823)
0.2 0.7 GO:0048030 disaccharide binding(GO:0048030)
0.2 0.8 GO:0015105 arsenite transmembrane transporter activity(GO:0015105)
0.2 0.7 GO:0097108 hedgehog family protein binding(GO:0097108)
0.2 3.0 GO:0008553 hydrogen-exporting ATPase activity, phosphorylative mechanism(GO:0008553)
0.2 0.7 GO:0003796 lysozyme activity(GO:0003796)
0.2 1.5 GO:0004865 protein serine/threonine phosphatase inhibitor activity(GO:0004865)
0.2 1.8 GO:0003872 6-phosphofructokinase activity(GO:0003872)
0.2 0.9 GO:0004743 pyruvate kinase activity(GO:0004743)
0.1 0.6 GO:0102345 3-hydroxyacyl-CoA dehydratase activity(GO:0018812) 3-hydroxy-behenoyl-CoA dehydratase activity(GO:0102344) 3-hydroxy-lignoceroyl-CoA dehydratase activity(GO:0102345)
0.1 1.6 GO:0004309 exopolyphosphatase activity(GO:0004309)
0.1 1.9 GO:0008327 methyl-CpG binding(GO:0008327)
0.1 1.1 GO:0001972 retinoic acid binding(GO:0001972)
0.1 0.8 GO:0005250 A-type (transient outward) potassium channel activity(GO:0005250)
0.1 0.5 GO:0015018 galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase activity(GO:0015018)
0.1 0.4 GO:0043395 heparan sulfate proteoglycan binding(GO:0043395)
0.1 1.4 GO:0032036 myosin heavy chain binding(GO:0032036)
0.1 0.7 GO:0019215 intermediate filament binding(GO:0019215)
0.1 0.9 GO:0008515 sugar:proton symporter activity(GO:0005351) cation:sugar symporter activity(GO:0005402) sucrose:proton symporter activity(GO:0008506) sucrose transmembrane transporter activity(GO:0008515) disaccharide transmembrane transporter activity(GO:0015154) oligosaccharide transmembrane transporter activity(GO:0015157)
0.1 1.6 GO:0005243 gap junction channel activity(GO:0005243)
0.1 0.5 GO:0005471 ATP:ADP antiporter activity(GO:0005471)
0.1 0.3 GO:0034185 apolipoprotein binding(GO:0034185)
0.1 0.3 GO:0004466 long-chain-acyl-CoA dehydrogenase activity(GO:0004466)
0.1 1.4 GO:0004111 creatine kinase activity(GO:0004111) phosphotransferase activity, nitrogenous group as acceptor(GO:0016775)
0.1 0.4 GO:0050211 procollagen galactosyltransferase activity(GO:0050211)
0.1 0.4 GO:0004657 proline dehydrogenase activity(GO:0004657)
0.1 0.3 GO:0010852 cyclase inhibitor activity(GO:0010852) guanylate cyclase inhibitor activity(GO:0030251)
0.1 0.6 GO:0008597 calcium-dependent protein serine/threonine phosphatase regulator activity(GO:0008597)
0.1 0.8 GO:0001517 N-acetylglucosamine 6-O-sulfotransferase activity(GO:0001517)
0.1 0.8 GO:0008467 [heparan sulfate]-glucosamine 3-sulfotransferase 1 activity(GO:0008467)
0.1 0.3 GO:0046923 ER retention sequence binding(GO:0046923)
0.1 0.3 GO:0005006 epidermal growth factor-activated receptor activity(GO:0005006)
0.1 1.1 GO:0005326 neurotransmitter transporter activity(GO:0005326)
0.1 0.3 GO:0008119 thiopurine S-methyltransferase activity(GO:0008119)
0.1 0.7 GO:0072320 volume-sensitive chloride channel activity(GO:0072320)
0.1 1.2 GO:0019911 structural constituent of myelin sheath(GO:0019911)
0.1 1.2 GO:0031682 G-protein gamma-subunit binding(GO:0031682)
0.1 0.6 GO:0019871 sodium channel inhibitor activity(GO:0019871)
0.1 0.5 GO:0050998 nitric-oxide synthase binding(GO:0050998)
0.1 0.6 GO:0003828 alpha-N-acetylneuraminate alpha-2,8-sialyltransferase activity(GO:0003828)
0.1 0.5 GO:0070579 methylcytosine dioxygenase activity(GO:0070579)
0.1 0.9 GO:0005021 vascular endothelial growth factor-activated receptor activity(GO:0005021)
0.1 1.0 GO:0015272 ATP-activated inward rectifier potassium channel activity(GO:0015272)
0.1 0.3 GO:0047757 chondroitin-glucuronate 5-epimerase activity(GO:0047757)
0.1 0.6 GO:0016933 extracellular-glycine-gated ion channel activity(GO:0016933) extracellular-glycine-gated chloride channel activity(GO:0016934)
0.1 0.3 GO:0015288 porin activity(GO:0015288)
0.1 1.0 GO:0016724 ferroxidase activity(GO:0004322) oxidoreductase activity, oxidizing metal ions, oxygen as acceptor(GO:0016724)
0.1 0.3 GO:0047192 1-alkylglycerophosphocholine O-acetyltransferase activity(GO:0047192)
0.1 1.0 GO:0038191 neuropilin binding(GO:0038191)
0.1 9.1 GO:0042803 protein homodimerization activity(GO:0042803)
0.1 1.6 GO:0005112 Notch binding(GO:0005112)
0.1 0.7 GO:0016861 intramolecular oxidoreductase activity, interconverting aldoses and ketoses(GO:0016861)
0.1 0.3 GO:0035529 NADH pyrophosphatase activity(GO:0035529)
0.1 0.9 GO:0005504 fatty acid binding(GO:0005504)
0.1 0.6 GO:0044323 retinoic acid-responsive element binding(GO:0044323)
0.1 0.6 GO:0008556 sodium:potassium-exchanging ATPase activity(GO:0005391) potassium-transporting ATPase activity(GO:0008556)
0.1 0.4 GO:0001641 group II metabotropic glutamate receptor activity(GO:0001641)
0.1 0.5 GO:0004563 beta-N-acetylhexosaminidase activity(GO:0004563)
0.1 0.2 GO:0017064 fatty acid amide hydrolase activity(GO:0017064)
0.1 4.7 GO:0005212 structural constituent of eye lens(GO:0005212)
0.1 1.6 GO:0008307 structural constituent of muscle(GO:0008307)
0.1 0.4 GO:0030160 GKAP/Homer scaffold activity(GO:0030160)
0.1 0.2 GO:0004903 growth hormone receptor activity(GO:0004903)
0.1 0.3 GO:0031420 potassium ion binding(GO:0030955) alkali metal ion binding(GO:0031420)
0.1 0.2 GO:0016652 NAD(P)+ transhydrogenase activity(GO:0008746) oxidoreductase activity, acting on NAD(P)H, NAD(P) as acceptor(GO:0016652)
0.1 0.3 GO:0070004 cysteine-type exopeptidase activity(GO:0070004)
0.1 1.5 GO:0004550 nucleoside diphosphate kinase activity(GO:0004550)
0.1 0.3 GO:0004142 diacylglycerol cholinephosphotransferase activity(GO:0004142) ethanolaminephosphotransferase activity(GO:0004307)
0.0 0.3 GO:0004960 thromboxane receptor activity(GO:0004960)
0.0 0.3 GO:0004974 leukotriene receptor activity(GO:0004974)
0.0 0.6 GO:0015183 L-glutamate transmembrane transporter activity(GO:0005313) acidic amino acid transmembrane transporter activity(GO:0015172) L-aspartate transmembrane transporter activity(GO:0015183)
0.0 0.2 GO:0051380 norepinephrine binding(GO:0051380)
0.0 0.3 GO:0004630 phospholipase D activity(GO:0004630)
0.0 0.7 GO:0043015 gamma-tubulin binding(GO:0043015)
0.0 0.3 GO:0000995 transcription factor activity, core RNA polymerase III binding(GO:0000995)
0.0 0.4 GO:0016936 galactoside binding(GO:0016936)
0.0 1.3 GO:0016769 transferase activity, transferring nitrogenous groups(GO:0016769)
0.0 0.6 GO:0004971 AMPA glutamate receptor activity(GO:0004971)
0.0 0.8 GO:0004806 triglyceride lipase activity(GO:0004806)
0.0 0.4 GO:0052812 phosphatidylinositol-4,5-bisphosphate 3-kinase activity(GO:0046934) phosphatidylinositol-3,4-bisphosphate 5-kinase activity(GO:0052812)
0.0 1.9 GO:0005546 phosphatidylinositol-4,5-bisphosphate binding(GO:0005546)
0.0 1.1 GO:0008331 high voltage-gated calcium channel activity(GO:0008331)
0.0 0.9 GO:0001540 beta-amyloid binding(GO:0001540)
0.0 0.1 GO:0008518 reduced folate carrier activity(GO:0008518) methotrexate transporter activity(GO:0015350)
0.0 1.5 GO:0005200 structural constituent of cytoskeleton(GO:0005200)
0.0 0.7 GO:0017080 sodium channel regulator activity(GO:0017080)
0.0 0.6 GO:0008519 ammonium transmembrane transporter activity(GO:0008519)
0.0 0.3 GO:0008273 calcium, potassium:sodium antiporter activity(GO:0008273)
0.0 0.2 GO:0032422 purine-rich negative regulatory element binding(GO:0032422)
0.0 6.8 GO:0050839 cell adhesion molecule binding(GO:0050839)
0.0 0.5 GO:0008330 protein tyrosine/threonine phosphatase activity(GO:0008330)
0.0 1.3 GO:0001786 phosphatidylserine binding(GO:0001786)
0.0 0.1 GO:0070224 sulfide:quinone oxidoreductase activity(GO:0070224)
0.0 0.1 GO:0015355 secondary active monocarboxylate transmembrane transporter activity(GO:0015355)
0.0 0.3 GO:0003876 AMP deaminase activity(GO:0003876) adenosine-phosphate deaminase activity(GO:0047623)
0.0 0.1 GO:0004394 heparan sulfate 2-O-sulfotransferase activity(GO:0004394)
0.0 0.6 GO:0051371 actinin binding(GO:0042805) muscle alpha-actinin binding(GO:0051371) alpha-actinin binding(GO:0051393)
0.0 0.1 GO:0038132 neuregulin receptor activity(GO:0038131) neuregulin binding(GO:0038132)
0.0 0.9 GO:0004198 calcium-dependent cysteine-type endopeptidase activity(GO:0004198)
0.0 0.7 GO:0008171 O-methyltransferase activity(GO:0008171)
0.0 0.4 GO:0004687 myosin light chain kinase activity(GO:0004687)
0.0 0.8 GO:0004016 adenylate cyclase activity(GO:0004016)
0.0 0.2 GO:0001968 fibronectin binding(GO:0001968)
0.0 1.5 GO:0015020 glucuronosyltransferase activity(GO:0015020)
0.0 0.5 GO:0008239 dipeptidyl-peptidase activity(GO:0008239)
0.0 0.1 GO:0047961 glycine N-acyltransferase activity(GO:0047961)
0.0 0.1 GO:0004301 epoxide hydrolase activity(GO:0004301)
0.0 0.4 GO:0045028 G-protein coupled nucleotide receptor activity(GO:0001608) G-protein coupled purinergic nucleotide receptor activity(GO:0045028)
0.0 0.6 GO:0031681 G-protein beta-subunit binding(GO:0031681)
0.0 0.4 GO:0005544 calcium-dependent phospholipid binding(GO:0005544)
0.0 0.5 GO:0098918 structural constituent of presynaptic active zone(GO:0098882) structural constituent of synapse(GO:0098918)
0.0 1.0 GO:0005184 neuropeptide hormone activity(GO:0005184)
0.0 0.3 GO:0043236 laminin binding(GO:0043236)
0.0 0.3 GO:0005332 gamma-aminobutyric acid:sodium symporter activity(GO:0005332)
0.0 0.7 GO:0032266 phosphatidylinositol-3-phosphate binding(GO:0032266)
0.0 2.1 GO:0008201 heparin binding(GO:0008201)
0.0 0.1 GO:0050699 WW domain binding(GO:0050699)
0.0 0.4 GO:0004720 protein-lysine 6-oxidase activity(GO:0004720)
0.0 0.3 GO:0015174 basic amino acid transmembrane transporter activity(GO:0015174)
0.0 0.1 GO:0015218 pyrimidine nucleotide transmembrane transporter activity(GO:0015218)
0.0 0.1 GO:0022829 wide pore channel activity(GO:0022829)
0.0 0.3 GO:0000828 inositol hexakisphosphate kinase activity(GO:0000828)
0.0 0.1 GO:0004418 hydroxymethylbilane synthase activity(GO:0004418)
0.0 0.4 GO:0003810 protein-glutamine gamma-glutamyltransferase activity(GO:0003810)
0.0 0.9 GO:0005251 delayed rectifier potassium channel activity(GO:0005251)
0.0 0.2 GO:0001665 alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase activity(GO:0001665)
0.0 0.2 GO:0005105 type 1 fibroblast growth factor receptor binding(GO:0005105)
0.0 0.1 GO:0061711 N(6)-L-threonylcarbamoyladenine synthase(GO:0061711)
0.0 0.5 GO:0000062 fatty-acyl-CoA binding(GO:0000062)
0.0 0.3 GO:0008266 poly(U) RNA binding(GO:0008266)
0.0 0.6 GO:0031683 G-protein beta/gamma-subunit complex binding(GO:0031683)
0.0 0.2 GO:0016721 superoxide dismutase activity(GO:0004784) oxidoreductase activity, acting on superoxide radicals as acceptor(GO:0016721)
0.0 0.3 GO:0097199 cysteine-type endopeptidase activity involved in apoptotic signaling pathway(GO:0097199)
0.0 0.2 GO:0005080 protein kinase C binding(GO:0005080)
0.0 0.2 GO:0051879 Hsp90 protein binding(GO:0051879)
0.0 0.1 GO:0016603 glutaminyl-peptide cyclotransferase activity(GO:0016603)
0.0 0.1 GO:0003938 IMP dehydrogenase activity(GO:0003938)
0.0 0.3 GO:0004382 guanosine-diphosphatase activity(GO:0004382) uridine-diphosphatase activity(GO:0045134)
0.0 0.1 GO:0004001 adenosine kinase activity(GO:0004001)
0.0 0.3 GO:0005005 transmembrane-ephrin receptor activity(GO:0005005)
0.0 0.2 GO:0005522 profilin binding(GO:0005522)
0.0 0.3 GO:0001671 ATPase activator activity(GO:0001671)
0.0 0.5 GO:0017147 Wnt-protein binding(GO:0017147)
0.0 0.3 GO:0042043 neurexin family protein binding(GO:0042043)
0.0 0.2 GO:0005000 vasopressin receptor activity(GO:0005000)
0.0 0.1 GO:0030116 glial cell-derived neurotrophic factor receptor binding(GO:0030116)
0.0 0.2 GO:1990404 protein ADP-ribosylase activity(GO:1990404)
0.0 0.1 GO:0050700 CARD domain binding(GO:0050700)
0.0 0.2 GO:0004157 dihydropyrimidinase activity(GO:0004157)
0.0 0.3 GO:0005104 fibroblast growth factor receptor binding(GO:0005104)
0.0 0.1 GO:0016303 1-phosphatidylinositol-3-kinase activity(GO:0016303) phosphatidylinositol 3-kinase activity(GO:0035004)
0.0 0.2 GO:0035612 AP-2 adaptor complex binding(GO:0035612)
0.0 0.2 GO:0016907 G-protein coupled acetylcholine receptor activity(GO:0016907)
0.0 0.3 GO:0016307 phosphatidylinositol phosphate kinase activity(GO:0016307)
0.0 0.1 GO:0004937 alpha1-adrenergic receptor activity(GO:0004937)
0.0 0.1 GO:0061133 endopeptidase activator activity(GO:0061133)
0.0 0.1 GO:0004104 cholinesterase activity(GO:0004104)
0.0 0.4 GO:0008195 phosphatidate phosphatase activity(GO:0008195)
0.0 0.2 GO:0047372 acylglycerol lipase activity(GO:0047372)
0.0 0.3 GO:0102336 fatty acid elongase activity(GO:0009922) 3-oxo-arachidoyl-CoA synthase activity(GO:0102336) 3-oxo-cerotoyl-CoA synthase activity(GO:0102337) 3-oxo-lignoceronyl-CoA synthase activity(GO:0102338)
0.0 0.1 GO:0046624 sphingolipid transporter activity(GO:0046624)
0.0 0.2 GO:0008301 DNA binding, bending(GO:0008301)
0.0 0.0 GO:0004133 glycogen debranching enzyme activity(GO:0004133) 4-alpha-glucanotransferase activity(GO:0004134) amylo-alpha-1,6-glucosidase activity(GO:0004135)
0.0 0.4 GO:0004364 glutathione transferase activity(GO:0004364)
0.0 1.3 GO:0005201 extracellular matrix structural constituent(GO:0005201)
0.0 0.3 GO:0005154 epidermal growth factor receptor binding(GO:0005154)
0.0 0.2 GO:1905030 voltage-gated sodium channel activity(GO:0005248) voltage-gated ion channel activity involved in regulation of postsynaptic membrane potential(GO:1905030)
0.0 9.1 GO:0005509 calcium ion binding(GO:0005509)
0.0 0.1 GO:0005030 neurotrophin receptor activity(GO:0005030)
0.0 0.1 GO:0001591 dopamine neurotransmitter receptor activity, coupled via Gi/Go(GO:0001591)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.9 PID SYNDECAN 3 PATHWAY Syndecan-3-mediated signaling events
0.1 2.3 PID INTEGRIN A9B1 PATHWAY Alpha9 beta1 integrin signaling events
0.0 1.5 PID HNF3B PATHWAY FOXA2 and FOXA3 transcription factor networks
0.0 0.4 PID IL5 PATHWAY IL5-mediated signaling events
0.0 0.6 PID CONE PATHWAY Visual signal transduction: Cones
0.0 0.5 PID SYNDECAN 2 PATHWAY Syndecan-2-mediated signaling events
0.0 1.6 PID HIF1 TFPATHWAY HIF-1-alpha transcription factor network
0.0 1.3 PID SYNDECAN 1 PATHWAY Syndecan-1-mediated signaling events
0.0 4.8 NABA ECM GLYCOPROTEINS Genes encoding structural ECM glycoproteins
0.0 1.0 NABA CORE MATRISOME Ensemble of genes encoding core extracellular matrix including ECM glycoproteins, collagens and proteoglycans
0.0 0.6 PID NEPHRIN NEPH1 PATHWAY Nephrin/Neph1 signaling in the kidney podocyte
0.0 0.4 PID IL12 STAT4 PATHWAY IL12 signaling mediated by STAT4
0.0 0.1 PID PI3KCI AKT PATHWAY Class I PI3K signaling events mediated by Akt
0.0 0.6 PID HEDGEHOG 2PATHWAY Signaling events mediated by the Hedgehog family
0.0 0.8 PID ATF2 PATHWAY ATF-2 transcription factor network
0.0 0.3 PID LPA4 PATHWAY LPA4-mediated signaling events
0.0 0.7 PID NOTCH PATHWAY Notch signaling pathway
0.0 0.3 PID AMB2 NEUTROPHILS PATHWAY amb2 Integrin signaling
0.0 0.9 NABA ECM AFFILIATED Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.0 0.1 PID S1P S1P2 PATHWAY S1P2 pathway
0.0 0.3 PID ALK1 PATHWAY ALK1 signaling events
0.0 0.1 SA G1 AND S PHASES Cdk2, 4, and 6 bind cyclin D in G1, while cdk2/cyclin E promotes the G1/S transition.

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 1.7 REACTOME CHYLOMICRON MEDIATED LIPID TRANSPORT Genes involved in Chylomicron-mediated lipid transport
0.2 0.8 REACTOME APOPTOSIS INDUCED DNA FRAGMENTATION Genes involved in Apoptosis induced DNA fragmentation
0.2 0.2 REACTOME SIGNALING BY CONSTITUTIVELY ACTIVE EGFR Genes involved in Signaling by constitutively active EGFR
0.1 0.3 REACTOME FGFR1 LIGAND BINDING AND ACTIVATION Genes involved in FGFR1 ligand binding and activation
0.1 2.4 REACTOME INHIBITION OF VOLTAGE GATED CA2 CHANNELS VIA GBETA GAMMA SUBUNITS Genes involved in Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits
0.1 0.8 REACTOME FGFR2C LIGAND BINDING AND ACTIVATION Genes involved in FGFR2c ligand binding and activation
0.1 1.2 REACTOME KERATAN SULFATE DEGRADATION Genes involved in Keratan sulfate degradation
0.1 0.9 REACTOME SYNTHESIS SECRETION AND INACTIVATION OF GLP1 Genes involved in Synthesis, Secretion, and Inactivation of Glucagon-like Peptide-1 (GLP-1)
0.1 1.6 REACTOME PLATELET CALCIUM HOMEOSTASIS Genes involved in Platelet calcium homeostasis
0.1 0.4 REACTOME DCC MEDIATED ATTRACTIVE SIGNALING Genes involved in DCC mediated attractive signaling
0.1 0.4 REACTOME ADP SIGNALLING THROUGH P2RY1 Genes involved in ADP signalling through P2Y purinoceptor 1
0.1 1.0 REACTOME IRON UPTAKE AND TRANSPORT Genes involved in Iron uptake and transport
0.1 2.0 REACTOME NCAM1 INTERACTIONS Genes involved in NCAM1 interactions
0.1 0.4 REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.1 0.4 REACTOME NEF MEDIATES DOWN MODULATION OF CELL SURFACE RECEPTORS BY RECRUITING THEM TO CLATHRIN ADAPTERS Genes involved in Nef-mediates down modulation of cell surface receptors by recruiting them to clathrin adapters
0.1 0.6 REACTOME G PROTEIN ACTIVATION Genes involved in G-protein activation
0.0 0.5 REACTOME HIGHLY CALCIUM PERMEABLE POSTSYNAPTIC NICOTINIC ACETYLCHOLINE RECEPTORS Genes involved in Highly calcium permeable postsynaptic nicotinic acetylcholine receptors
0.0 0.9 REACTOME GLYCOLYSIS Genes involved in Glycolysis
0.0 0.6 REACTOME POST CHAPERONIN TUBULIN FOLDING PATHWAY Genes involved in Post-chaperonin tubulin folding pathway
0.0 0.5 REACTOME INTRINSIC PATHWAY Genes involved in Intrinsic Pathway
0.0 0.3 REACTOME EICOSANOID LIGAND BINDING RECEPTORS Genes involved in Eicosanoid ligand-binding receptors
0.0 0.1 REACTOME ABACAVIR TRANSPORT AND METABOLISM Genes involved in Abacavir transport and metabolism
0.0 0.3 REACTOME PKA MEDIATED PHOSPHORYLATION OF CREB Genes involved in PKA-mediated phosphorylation of CREB
0.0 0.3 REACTOME ERKS ARE INACTIVATED Genes involved in ERKs are inactivated
0.0 0.4 REACTOME DARPP 32 EVENTS Genes involved in DARPP-32 events
0.0 1.5 REACTOME RESPIRATORY ELECTRON TRANSPORT Genes involved in Respiratory electron transport
0.0 0.4 REACTOME SYNTHESIS OF PC Genes involved in Synthesis of PC
0.0 0.3 REACTOME MITOCHONDRIAL FATTY ACID BETA OXIDATION Genes involved in Mitochondrial Fatty Acid Beta-Oxidation
0.0 0.3 REACTOME ACYL CHAIN REMODELLING OF PC Genes involved in Acyl chain remodelling of PC
0.0 0.2 REACTOME PYRIMIDINE CATABOLISM Genes involved in Pyrimidine catabolism
0.0 0.3 REACTOME RNA POL I PROMOTER OPENING Genes involved in RNA Polymerase I Promoter Opening
0.0 0.4 REACTOME KERATAN SULFATE BIOSYNTHESIS Genes involved in Keratan sulfate biosynthesis
0.0 0.4 REACTOME REGULATION OF SIGNALING BY CBL Genes involved in Regulation of signaling by CBL
0.0 1.1 REACTOME INTEGRIN CELL SURFACE INTERACTIONS Genes involved in Integrin cell surface interactions
0.0 0.8 REACTOME NRAGE SIGNALS DEATH THROUGH JNK Genes involved in NRAGE signals death through JNK
0.0 0.1 REACTOME NUCLEOTIDE BINDING DOMAIN LEUCINE RICH REPEAT CONTAINING RECEPTOR NLR SIGNALING PATHWAYS Genes involved in Nucleotide-binding domain, leucine rich repeat containing receptor (NLR) signaling pathways
0.0 0.9 REACTOME FORMATION OF THE TERNARY COMPLEX AND SUBSEQUENTLY THE 43S COMPLEX Genes involved in Formation of the ternary complex, and subsequently, the 43S complex
0.0 0.3 REACTOME BASIGIN INTERACTIONS Genes involved in Basigin interactions
0.0 0.5 REACTOME VOLTAGE GATED POTASSIUM CHANNELS Genes involved in Voltage gated Potassium channels
0.0 1.0 REACTOME PEPTIDE CHAIN ELONGATION Genes involved in Peptide chain elongation
0.0 2.4 REACTOME METABOLISM OF AMINO ACIDS AND DERIVATIVES Genes involved in Metabolism of amino acids and derivatives
0.0 0.2 REACTOME A TETRASACCHARIDE LINKER SEQUENCE IS REQUIRED FOR GAG SYNTHESIS Genes involved in A tetrasaccharide linker sequence is required for GAG synthesis
0.0 0.3 REACTOME MYOGENESIS Genes involved in Myogenesis
0.0 0.8 REACTOME SIGNALING BY RHO GTPASES Genes involved in Signaling by Rho GTPases
0.0 0.2 REACTOME CITRIC ACID CYCLE TCA CYCLE Genes involved in Citric acid cycle (TCA cycle)
0.0 0.5 REACTOME CLASS B 2 SECRETIN FAMILY RECEPTORS Genes involved in Class B/2 (Secretin family receptors)