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PRJNA195909:zebrafish embryo and larva development

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Results for osr1

Z-value: 1.89

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Transcription factors associated with osr1

Gene Symbol Gene ID Gene Info
ENSDARG00000014091 odd-skipped related transcription factor 1

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
osr1dr11_v1_chr13_+_32144370_321443700.684.5e-02Click!

Activity profile of osr1 motif

Sorted Z-values of osr1 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr7_+_29954709 4.83 ENSDART00000173904
alpha-tropomyosin
chr3_-_55139127 4.46 ENSDART00000115324
hemoglobin, alpha embryonic 1.3
chr7_+_29955368 4.36 ENSDART00000173686
alpha-tropomyosin
chr14_-_26536504 3.88 ENSDART00000105933
transforming growth factor, beta-induced
chr9_-_45601103 3.67 ENSDART00000180465
anterior gradient 1
chr1_+_17593392 3.41 ENSDART00000078889
helt bHLH transcription factor
chr9_-_22069364 3.11 ENSDART00000101938
crystallin, gamma M2b
chr3_-_61181018 2.96 ENSDART00000187970
parvalbumin 4
chr18_-_45736 2.89 ENSDART00000148373
ENSDART00000148950
glycine amidinotransferase (L-arginine:glycine amidinotransferase)
chr18_-_46010 2.85 ENSDART00000052641
glycine amidinotransferase (L-arginine:glycine amidinotransferase)
chr14_+_51098036 2.84 ENSDART00000184118

chr9_-_22023061 2.42 ENSDART00000101952
crystallin, gamma M2c
chr2_+_56463167 2.36 ENSDART00000123392
RAB11B, member RAS oncogene family, b
chr1_-_58064738 2.36 ENSDART00000073778
caspase b
chr7_+_44713135 2.21 ENSDART00000170721
si:dkey-56m19.5
chr1_-_40911332 2.07 ENSDART00000027463
H6 family homeobox 4
chr7_-_27033080 2.03 ENSDART00000173516
nucleobindin 2a
chr3_-_37758487 2.03 ENSDART00000150938
si:dkey-260c8.6
chr3_-_29899172 2.01 ENSDART00000140518
ENSDART00000020311
ribosomal protein L27
chr15_-_39848822 1.94 ENSDART00000155230
si:dkey-263j23.1
chr23_-_31403668 1.90 ENSDART00000147498

chr13_-_992458 1.88 ENSDART00000114655
beaded filament structural protein 1
chr19_+_31576849 1.81 ENSDART00000134107
ENSDART00000088401
acyl-CoA thioesterase 13
chr17_+_31185276 1.80 ENSDART00000062887
dispatched homolog 2 (Drosophila)
chr18_-_46258612 1.73 ENSDART00000153930
si:dkey-244a7.1
chr18_+_30847237 1.71 ENSDART00000012374
forkhead box F1
chr11_+_14199802 1.70 ENSDART00000102520
ENSDART00000133172
paralemmin 1a
chr10_+_19554604 1.68 ENSDART00000063806
ATPase H+ transporting V1 subunit B2
chr13_-_1408775 1.66 ENSDART00000049684
BCL2 associated athanogene 2
chr18_-_977075 1.64 ENSDART00000032392
dihydrodiol dehydrogenase (dimeric), like
chr5_-_24201437 1.60 ENSDART00000114113
SRY (sex determining region Y)-box 19a
chr11_+_2198831 1.57 ENSDART00000160515
homeobox C6b
chr7_+_26534131 1.55 ENSDART00000173980
si:dkey-62k3.5
chr16_-_26537103 1.55 ENSDART00000134908
ENSDART00000008152
serum/glucocorticoid regulated kinase 2b
chr22_-_5006801 1.53 ENSDART00000106166
retinal homeobox gene 1
chr10_-_25860102 1.51 ENSDART00000080789
transient receptor potential cation channel, subfamily C, member 4a
chr14_+_4151379 1.48 ENSDART00000160431
dehydrogenase/reductase (SDR family) member 13 like 1
chr16_-_46660680 1.47 ENSDART00000159209
ENSDART00000191929
transmembrane protein 176l.4
chr5_-_56513825 1.47 ENSDART00000024207
T-box 2a
chr22_-_28871787 1.46 ENSDART00000104828
GTP binding protein 2b
chr22_-_11626014 1.45 ENSDART00000063133
ENSDART00000160085
glucagon a
chr1_-_22861348 1.44 ENSDART00000139412
si:dkey-92j12.6
chr13_+_28417297 1.42 ENSDART00000043658
solute carrier family 2 (facilitated glucose transporter), member 15a
chr20_-_29787192 1.40 ENSDART00000125348
ENSDART00000048759
inhibitor of DNA binding 2b
chr5_-_36949476 1.39 ENSDART00000047269
H3 histone, family 3C
chr14_-_40390757 1.39 ENSDART00000149443
protocadherin 19
chr10_-_13239367 1.37 ENSDART00000001253
si:busm1-57f23.1
chr7_+_22767678 1.35 ENSDART00000137203
plac8 onzin related protein 6
chr14_-_24391424 1.34 ENSDART00000113376
ENSDART00000126894
family with sequence similarity 13, member B
chr20_-_9436521 1.34 ENSDART00000133000
zgc:101840
chr2_-_11512819 1.32 ENSDART00000142013
proenkephalin a
chr2_-_9646857 1.32 ENSDART00000056901
zgc:153615
chr23_-_46040618 1.31 ENSDART00000161415

chr12_-_38548299 1.28 ENSDART00000153374
si:dkey-1f1.3
chr24_+_10413484 1.28 ENSDART00000111014
MYC proto-oncogene, bHLH transcription factor a
chr1_-_21723329 1.28 ENSDART00000137138
si:ch211-134c9.2
chr13_-_11536951 1.27 ENSDART00000018155
adenylosuccinate synthase
chr1_-_21344478 1.26 ENSDART00000077805
glutamate receptor, ionotropic, AMPA 2a
chr21_+_33454147 1.24 ENSDART00000053208
ribosomal protein S14
chr21_-_15674802 1.23 ENSDART00000136666
matrix metallopeptidase 11b
chr2_-_37896965 1.22 ENSDART00000129852
hexose-binding lectin 1
chr20_-_5291012 1.21 ENSDART00000122892
cytochrome P450, family 46, subfamily A, polypeptide 1, tandem duplicate 3
chr10_+_38512270 1.19 ENSDART00000109752
serpin peptidase inhibitor, clade H (heat shock protein 47), member 1a
chr2_-_51096647 1.18 ENSDART00000167172
si:ch73-52e5.2
chr12_+_31713239 1.18 ENSDART00000122379
hyaluronan binding protein 2
chr19_-_35361556 1.17 ENSDART00000012167
NADH dehydrogenase (ubiquinone) Fe-S protein 5
chr5_-_48307804 1.17 ENSDART00000182831
ENSDART00000186920
ENSDART00000183585
myocyte enhancer factor 2cb
chr18_+_46382484 1.16 ENSDART00000024202
ENSDART00000142790
dynein assembly factor with WDR repeat domains 1
chr1_+_23783349 1.16 ENSDART00000007531
slit homolog 2 (Drosophila)
chr20_-_29418620 1.14 ENSDART00000172634
ryanodine receptor 3
chr1_-_59130695 1.12 ENSDART00000152560

chr9_-_33121535 1.11 ENSDART00000166371
ENSDART00000138052
zgc:172014
chr2_-_30668580 1.09 ENSDART00000087270
catenin (cadherin-associated protein), delta 2b
chr5_+_69808763 1.09 ENSDART00000143482
fibronectin type III and SPRY domain containing 1-like
chr3_-_30123113 1.08 ENSDART00000153562
protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 3
chr11_+_21053488 1.08 ENSDART00000189860
zgc:113307
chr11_-_33960318 1.07 ENSDART00000087597
collagen, type VI, alpha 2
chr22_-_21314821 1.07 ENSDART00000105546
ENSDART00000135388
CDC28 protein kinase regulatory subunit 2
chr4_+_47257854 1.06 ENSDART00000173868
crestin
chr13_-_32635859 1.05 ENSDART00000146249
ENSDART00000145395
ENSDART00000148040
ENSDART00000100650
matrilin 3b
chr10_+_21559605 1.05 ENSDART00000123648
ENSDART00000108584
protocadherin 1 alpha 3
protocadherin 1 alpha 3
chr4_-_6567355 1.04 ENSDART00000134820
ENSDART00000142087
forkhead box P2
chr19_-_25519310 1.02 ENSDART00000089882
si:dkey-202e17.1
chr18_+_21408794 1.01 ENSDART00000140161
N-terminal EF-hand calcium binding protein 2
chr3_-_53722182 1.01 ENSDART00000032788
retinol dehydrogenase 8a
chr16_-_28876479 0.99 ENSDART00000047862
si:dkey-239n17.4
chr8_+_4798158 0.99 ENSDART00000031650
heat shock cognate 70-kd protein, like
chr8_-_2506327 0.98 ENSDART00000101125
ENSDART00000125124
ribosomal protein L6
chr2_-_20574193 0.98 ENSDART00000190448
si:ch211-267e7.3
chr13_+_30696286 0.98 ENSDART00000192411
chemokine (C-X-C motif) ligand 18a, duplicate 1
chr16_+_35344031 0.97 ENSDART00000167140
si:dkey-34d22.1
chr12_-_2993095 0.97 ENSDART00000152316
si:dkey-202c14.3
chr7_+_33314925 0.97 ENSDART00000148590
coronin, actin binding protein, 2Ba
chr25_+_34581494 0.96 ENSDART00000167690
transient receptor potential cation channel, subfamily M, member 1b
chr7_+_31871830 0.96 ENSDART00000139899
myosin binding protein C, cardiac
chr4_-_1824836 0.96 ENSDART00000111858
mitochondrial ribosomal protein L42
chr20_+_1412193 0.95 ENSDART00000064419
liver-enriched gene 1, tandem duplicate 1
chr13_-_45523026 0.95 ENSDART00000020663
Rh blood group, D antigen
chr9_-_18568927 0.95 ENSDART00000084668
ecto-NOX disulfide-thiol exchanger 1
chr4_+_3287819 0.94 ENSDART00000168633

chr14_-_17072736 0.93 ENSDART00000106333
paired-like homeobox 2bb
chr21_+_4702773 0.93 ENSDART00000147404
si:dkey-102g19.3
chr14_+_29769336 0.92 ENSDART00000105898
si:dkey-34l15.1
chr18_-_49116382 0.91 ENSDART00000174157

chr22_+_661711 0.88 ENSDART00000113795
E74-like factor 3 (ets domain transcription factor, epithelial-specific )
chr14_-_13048355 0.88 ENSDART00000166434
si:dkey-35h6.1
chr19_-_9712530 0.87 ENSDART00000134816
solute carrier family 2 (facilitated glucose transporter), member 3a
chr25_-_31433512 0.87 ENSDART00000067028
zgc:172145
chr18_+_30507839 0.86 ENSDART00000026866
cytochrome c oxidase subunit IV isoform 1
chr19_+_14921000 0.85 ENSDART00000144052
opioid receptor, delta 1a
chr9_-_12424231 0.84 ENSDART00000188952
zgc:162707
chr11_-_36350876 0.83 ENSDART00000146495
ENSDART00000020655
proteasome subunit alpha 5
chr20_+_30490682 0.83 ENSDART00000184871
myelin transcription factor 1-like, a
chr12_-_45669050 0.82 ENSDART00000124455
F-box and leucine-rich repeat protein 15
chr4_+_8569199 0.82 ENSDART00000165181
wingless-type MMTV integration site family, member 5b
chr4_-_23908802 0.81 ENSDART00000138873
cugbp, Elav-like family member 2
chr8_-_50981175 0.81 ENSDART00000004065
zgc:91909
chr14_+_35901249 0.78 ENSDART00000105604
zgc:77938
chr4_-_67969695 0.78 ENSDART00000190016
si:ch211-223k15.1
chr23_-_9925568 0.77 ENSDART00000081268
si:ch211-220i18.4
chr6_-_19035749 0.75 ENSDART00000187714
septin 9b
chr19_-_5769553 0.74 ENSDART00000175003
si:ch211-264f5.6
chr19_-_25519612 0.74 ENSDART00000133150
si:dkey-202e17.1
chr7_+_48805534 0.74 ENSDART00000145375
ENSDART00000148744
carnitine palmitoyltransferase 1Aa (liver)
chr14_+_49135264 0.73 ENSDART00000084119
si:ch1073-44g3.1
chr9_-_5263947 0.72 ENSDART00000088342
cytohesin 1 interacting protein
chr23_-_30785382 0.72 ENSDART00000136156
ENSDART00000131285
myelin transcription factor 1a
chr9_-_306515 0.71 ENSDART00000166059
si:ch211-166e11.5
chr5_-_5831037 0.71 ENSDART00000112856
zmp:0000000846
chr2_+_20539402 0.70 ENSDART00000129585
si:ch73-14h1.2
chr2_-_9748039 0.69 ENSDART00000134870
si:ch1073-170o4.1
chr20_+_16881883 0.68 ENSDART00000130107
nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha a
chr7_-_4036875 0.67 ENSDART00000165021
NDRG family member 2
chr15_-_12011202 0.67 ENSDART00000160427
ENSDART00000168715
si:dkey-202l22.6
chr21_+_45627775 0.67 ENSDART00000185466
interferon regulatory factor 1b
chr12_-_45876387 0.67 ENSDART00000043210
ENSDART00000149044
paired box 2b
chr7_-_59564011 0.66 ENSDART00000186053
zgc:112271
chr6_-_48087152 0.65 ENSDART00000180614
solute carrier family 2 (facilitated glucose transporter), member 1b
chr3_+_15805917 0.65 ENSDART00000055834
phosphatase, orphan 1
chr5_-_55981288 0.65 ENSDART00000146616
si:dkey-189h5.6
chr3_-_26115558 0.64 ENSDART00000078671
ENSDART00000124762
heat shock cognate 70-kd protein, tandem duplicate 1
chr3_-_38918697 0.62 ENSDART00000145630
si:dkey-106c17.2
chr2_+_22531185 0.62 ENSDART00000171959
HFM1, ATP-dependent DNA helicase homolog (S. cerevisiae)
chr13_-_27038407 0.62 ENSDART00000146712
coiled-coil domain containing 85A
chr21_-_40083432 0.60 ENSDART00000141160
ENSDART00000191195
info solute carrier family 13 (sodium-dependent citrate transporter), member 5a
chr1_+_52563298 0.60 ENSDART00000142465
ATP-binding cassette, sub-family A (ABC1), member 1A
chr8_+_49778756 0.58 ENSDART00000083790
neurotrophic tyrosine kinase, receptor, type 2a
chr4_-_12323228 0.58 ENSDART00000081089
interleukin 17 receptor A1a
chr24_-_9960290 0.58 ENSDART00000143390
ENSDART00000092975
ENSDART00000184953
vacuolar protein sorting 41 homolog (S. cerevisiae)
chr2_-_37896646 0.57 ENSDART00000075931
hexose-binding lectin 1
chr1_-_8140763 0.56 ENSDART00000091508
si:dkeyp-9d4.4
chr1_+_54650048 0.55 ENSDART00000141207
si:ch211-202h22.7
chr13_+_18663600 0.55 ENSDART00000141647
selenoprotein U 1a
chr17_-_22021213 0.54 ENSDART00000078843
zmp:0000001102
chr15_-_35960250 0.54 ENSDART00000186765
collagen, type IV, alpha 4
chr21_-_26490186 0.53 ENSDART00000009889
zgc:110540
chr10_+_2587234 0.52 ENSDART00000126937
wu:fb59d01
chr9_-_21098413 0.52 ENSDART00000018570
tryptophanyl tRNA synthetase 2, mitochondrial
chr14_+_5383060 0.52 ENSDART00000187825
ladybird homeobox 2
chr13_+_50151407 0.52 ENSDART00000031858
G protein-coupled receptor 137Ba
chr24_+_1294176 0.52 ENSDART00000106637
si:ch73-134f24.1
chr3_+_19460991 0.50 ENSDART00000169124
phosphodiesterase 6G, cGMP-specific, rod, gamma, paralog a
chr14_+_17137023 0.50 ENSDART00000080712
solute carrier family 43, member 3b
chr13_+_40686133 0.49 ENSDART00000146112
Hermansky-Pudlak syndrome 1
chr2_-_4868002 0.49 ENSDART00000189835
transferrin receptor 1a
chr12_-_7824291 0.49 ENSDART00000148673
ENSDART00000149453
ankyrin 3b
chr14_-_17305849 0.48 ENSDART00000160971
janus kinase and microtubule interacting protein 1
chr2_+_5446882 0.48 ENSDART00000083260
dual specificity phosphatase 28
chr11_+_31285127 0.48 ENSDART00000160154
si:dkey-238i5.2
chr16_+_20871021 0.47 ENSDART00000006429
3-hydroxyisobutyrate dehydrogenase b
chr20_+_10727022 0.47 ENSDART00000104185
si:ch211-182e10.4
chr14_+_22680485 0.46 ENSDART00000167829
GDNF family receptor alpha 4b
chr7_+_48805725 0.46 ENSDART00000166543
carnitine palmitoyltransferase 1Aa (liver)
chr12_+_48815988 0.46 ENSDART00000149089
annexin A11b
chr21_-_25295087 0.46 ENSDART00000087910
ENSDART00000147860
suppression of tumorigenicity 14 (colon carcinoma) b
chr6_-_8407406 0.46 ENSDART00000151355
prostaglandin E receptor 1a (subtype EP1)
chr14_-_17306261 0.45 ENSDART00000191747
janus kinase and microtubule interacting protein 1
chr7_+_20656942 0.45 ENSDART00000100898
TNF superfamily member 12
chr13_+_35746440 0.45 ENSDART00000187859
G protein-coupled receptor 75
chr15_-_576135 0.45 ENSDART00000124170
cerebellin 20
chr17_-_6198823 0.44 ENSDART00000028407
ENSDART00000193636
protein tyrosine kinase 2 beta, a
chr9_-_4856767 0.44 ENSDART00000016814
ENSDART00000138015
formin-like 2a
chr17_-_45104750 0.43 ENSDART00000075520
aldehyde dehydrogenase 6 family, member A1
chr1_+_9886991 0.43 ENSDART00000135702
regulator of G protein signaling 11
chr15_+_3219134 0.42 ENSDART00000113532

chr23_+_7379728 0.42 ENSDART00000012194
GATA binding protein 5
chr3_-_32958505 0.42 ENSDART00000147374
ENSDART00000136919
caspase 6, apoptosis-related cysteine peptidase, like 1
chr3_-_16285861 0.41 ENSDART00000140103
branched chain keto acid dehydrogenase E1, beta polypeptide, like
chr21_-_40834413 0.41 ENSDART00000148513
LIM domain kinase 1b
chr2_+_3986083 0.41 ENSDART00000188979
mohawk homeobox b
chr6_+_49082796 0.40 ENSDART00000182446
thyroid stimulating hormone, beta subunit, a
chr10_+_3875716 0.39 ENSDART00000189268
ENSDART00000180624
tetratricopeptide repeat domain 28
chr11_-_36279602 0.39 ENSDART00000122531
ENSDART00000103064
ENSDART00000125616
nuclear transcription factor Y, alpha
chr25_-_13659249 0.39 ENSDART00000045488
casein kinase 2, alpha prime polypeptide b
chr8_+_30709685 0.38 ENSDART00000133989
ureidopropionase, beta
chr6_-_41229787 0.38 ENSDART00000065013
synaptoporin
chr20_+_36010080 0.38 ENSDART00000021456
opsin 5
chr19_-_26823647 0.37 ENSDART00000002464
neuraminidase 1
chr6_-_40884453 0.37 ENSDART00000017968
ENSDART00000154100
sirtuin 4
chr20_+_53522059 0.37 ENSDART00000147570
p21 protein (Cdc42/Rac)-activated kinase 6b

Network of associatons between targets according to the STRING database.

First level regulatory network of osr1

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
1.9 5.7 GO:0006600 creatine metabolic process(GO:0006600) creatine biosynthetic process(GO:0006601)
0.5 1.5 GO:0072068 distal convoluted tubule development(GO:0072025) late distal convoluted tubule development(GO:0072068)
0.4 1.2 GO:0007414 axonal defasciculation(GO:0007414)
0.3 1.3 GO:1904105 positive regulation of convergent extension involved in gastrulation(GO:1904105)
0.2 0.9 GO:0061549 sympathetic ganglion development(GO:0061549)
0.2 0.7 GO:1901533 negative regulation of hematopoietic progenitor cell differentiation(GO:1901533)
0.2 1.3 GO:0035332 positive regulation of hippo signaling(GO:0035332)
0.2 0.9 GO:0038003 opioid receptor signaling pathway(GO:0038003)
0.2 4.5 GO:0015671 oxygen transport(GO:0015671)
0.2 2.0 GO:0032096 negative regulation of response to food(GO:0032096) negative regulation of appetite(GO:0032099)
0.2 0.6 GO:0099551 synaptic signaling via neuropeptide(GO:0099538) trans-synaptic signaling by neuropeptide(GO:0099540) trans-synaptic signaling by neuropeptide, modulating synaptic transmission(GO:0099551) cellular response to brain-derived neurotrophic factor stimulus(GO:1990416)
0.2 1.0 GO:0003210 cardiac atrium formation(GO:0003210)
0.2 1.0 GO:0007624 ultradian rhythm(GO:0007624)
0.2 0.5 GO:0045671 negative regulation of osteoclast differentiation(GO:0045671)
0.2 2.1 GO:1900052 regulation of isoprenoid metabolic process(GO:0019747) regulation of vitamin metabolic process(GO:0030656) regulation of retinoic acid biosynthetic process(GO:1900052)
0.2 0.9 GO:0006574 valine catabolic process(GO:0006574)
0.1 0.6 GO:0010874 regulation of cholesterol efflux(GO:0010874)
0.1 1.0 GO:0042984 amyloid precursor protein biosynthetic process(GO:0042983) regulation of amyloid precursor protein biosynthetic process(GO:0042984)
0.1 1.0 GO:0006703 estrogen biosynthetic process(GO:0006703)
0.1 0.9 GO:0006880 intracellular sequestering of iron ion(GO:0006880) sequestering of iron ion(GO:0097577)
0.1 0.5 GO:1903232 melanosome assembly(GO:1903232)
0.1 0.5 GO:0015682 ferric iron transport(GO:0015682) transferrin transport(GO:0033572) trivalent inorganic cation transport(GO:0072512)
0.1 1.2 GO:0031998 regulation of fatty acid beta-oxidation(GO:0031998)
0.1 1.0 GO:0072488 ammonium transmembrane transport(GO:0072488)
0.1 1.2 GO:0006842 tricarboxylic acid transport(GO:0006842) citrate transport(GO:0015746)
0.1 0.8 GO:0046292 formaldehyde metabolic process(GO:0046292) formaldehyde catabolic process(GO:0046294)
0.1 1.2 GO:0006707 cholesterol catabolic process(GO:0006707) sterol catabolic process(GO:0016127)
0.1 0.4 GO:0048618 post-embryonic foregut morphogenesis(GO:0048618)
0.1 1.6 GO:0048899 anterior lateral line development(GO:0048899)
0.1 1.0 GO:1990402 embryonic liver development(GO:1990402)
0.1 0.4 GO:0016038 absorption of visible light(GO:0016038)
0.1 1.6 GO:0046686 response to cadmium ion(GO:0046686)
0.1 9.4 GO:0061515 myeloid cell development(GO:0061515)
0.1 0.5 GO:0045745 positive regulation of G-protein coupled receptor protein signaling pathway(GO:0045745)
0.1 1.5 GO:0042574 retinal metabolic process(GO:0042574)
0.1 0.4 GO:0019482 beta-alanine metabolic process(GO:0019482) beta-alanine biosynthetic process(GO:0019483)
0.1 0.6 GO:0034058 endosomal vesicle fusion(GO:0034058)
0.1 0.9 GO:0006123 mitochondrial electron transport, cytochrome c to oxygen(GO:0006123)
0.1 0.3 GO:0048913 anterior lateral line nerve glial cell differentiation(GO:0048913) myelination of anterior lateral line nerve axons(GO:0048914) anterior lateral line nerve glial cell development(GO:0048939) anterior lateral line nerve glial cell morphogenesis involved in differentiation(GO:0048940)
0.1 1.0 GO:0045471 response to ethanol(GO:0045471)
0.1 0.4 GO:0007172 signal complex assembly(GO:0007172)
0.1 0.3 GO:0036371 protein localization to T-tubule(GO:0036371)
0.1 1.2 GO:0060285 cilium or flagellum-dependent cell motility(GO:0001539) cilium-dependent cell motility(GO:0060285)
0.1 0.2 GO:0014909 smooth muscle cell migration(GO:0014909)
0.1 1.2 GO:0097031 NADH dehydrogenase complex assembly(GO:0010257) mitochondrial respiratory chain complex I assembly(GO:0032981) mitochondrial respiratory chain complex I biogenesis(GO:0097031)
0.1 0.7 GO:0050688 regulation of defense response to virus(GO:0050688)
0.1 0.2 GO:0070227 lymphocyte apoptotic process(GO:0070227)
0.0 0.2 GO:0070166 enamel mineralization(GO:0070166)
0.0 1.6 GO:0006919 activation of cysteine-type endopeptidase activity involved in apoptotic process(GO:0006919)
0.0 1.7 GO:0050821 protein stabilization(GO:0050821)
0.0 1.7 GO:0030199 collagen fibril organization(GO:0030199)
0.0 5.5 GO:0002088 lens development in camera-type eye(GO:0002088)
0.0 0.2 GO:1901380 negative regulation of potassium ion transmembrane transporter activity(GO:1901017) negative regulation of potassium ion transmembrane transport(GO:1901380) negative regulation of delayed rectifier potassium channel activity(GO:1902260) negative regulation of voltage-gated potassium channel activity(GO:1903817)
0.0 1.0 GO:0000027 ribosomal large subunit assembly(GO:0000027)
0.0 0.8 GO:0048512 rhythmic behavior(GO:0007622) circadian behavior(GO:0048512)
0.0 1.2 GO:0030574 collagen catabolic process(GO:0030574) multicellular organism catabolic process(GO:0044243)
0.0 1.1 GO:0060997 dendritic spine morphogenesis(GO:0060997)
0.0 0.2 GO:0019348 dolichol metabolic process(GO:0019348)
0.0 3.9 GO:0071466 cellular response to xenobiotic stimulus(GO:0071466)
0.0 0.7 GO:0006879 cellular iron ion homeostasis(GO:0006879)
0.0 1.6 GO:0035195 gene silencing by miRNA(GO:0035195)
0.0 0.1 GO:0019276 UDP-N-acetylgalactosamine metabolic process(GO:0019276)
0.0 1.4 GO:0048854 brain morphogenesis(GO:0048854)
0.0 1.4 GO:0032922 circadian regulation of gene expression(GO:0032922)
0.0 1.6 GO:0000245 spliceosomal complex assembly(GO:0000245)
0.0 0.4 GO:0009313 oligosaccharide catabolic process(GO:0009313)
0.0 0.8 GO:0030513 positive regulation of BMP signaling pathway(GO:0030513)
0.0 0.2 GO:1905168 positive regulation of double-strand break repair via homologous recombination(GO:1905168) regulation of double-strand break repair via nonhomologous end joining(GO:2001032)
0.0 0.1 GO:2000425 regulation of apoptotic cell clearance(GO:2000425)
0.0 0.3 GO:1904071 presynaptic active zone assembly(GO:1904071)
0.0 1.3 GO:0051262 protein tetramerization(GO:0051262)
0.0 0.8 GO:0010499 proteasomal ubiquitin-independent protein catabolic process(GO:0010499)
0.0 1.3 GO:0051091 positive regulation of sequence-specific DNA binding transcription factor activity(GO:0051091)
0.0 1.5 GO:0010842 retina layer formation(GO:0010842)
0.0 1.2 GO:0060914 heart formation(GO:0060914)
0.0 0.6 GO:0070167 regulation of bone mineralization(GO:0030500) regulation of biomineral tissue development(GO:0070167)
0.0 0.1 GO:2000767 positive regulation of cytoplasmic translation(GO:2000767)
0.0 2.2 GO:0031101 fin regeneration(GO:0031101)
0.0 0.5 GO:0006418 tRNA aminoacylation for protein translation(GO:0006418)
0.0 1.7 GO:1902600 hydrogen ion transmembrane transport(GO:1902600)
0.0 1.5 GO:0006414 translational elongation(GO:0006414)
0.0 0.4 GO:0051496 positive regulation of stress fiber assembly(GO:0051496)
0.0 0.3 GO:0048312 intracellular distribution of mitochondria(GO:0048312)
0.0 0.3 GO:0046501 protoporphyrinogen IX biosynthetic process(GO:0006782) protoporphyrinogen IX metabolic process(GO:0046501)
0.0 2.1 GO:0008360 regulation of cell shape(GO:0008360)
0.0 1.6 GO:0030218 erythrocyte differentiation(GO:0030218)
0.0 0.5 GO:0006828 manganese ion transport(GO:0006828)
0.0 1.3 GO:1901342 regulation of vasculature development(GO:1901342)
0.0 2.1 GO:0002040 sprouting angiogenesis(GO:0002040)
0.0 0.3 GO:0032008 positive regulation of TOR signaling(GO:0032008)
0.0 0.1 GO:0046959 nonassociative learning(GO:0046958) habituation(GO:0046959)
0.0 1.2 GO:0007218 neuropeptide signaling pathway(GO:0007218)
0.0 1.1 GO:0007224 smoothened signaling pathway(GO:0007224)
0.0 3.7 GO:0009952 anterior/posterior pattern specification(GO:0009952)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.7 2.0 GO:0098556 cytoplasmic side of rough endoplasmic reticulum membrane(GO:0098556)
0.6 2.4 GO:0061702 inflammasome complex(GO:0061702)
0.4 4.5 GO:0031838 haptoglobin-hemoglobin complex(GO:0031838)
0.2 1.1 GO:0005790 smooth endoplasmic reticulum(GO:0005790)
0.1 0.5 GO:0031085 BLOC-3 complex(GO:0031085)
0.1 1.7 GO:0033180 proton-transporting V-type ATPase, V1 domain(GO:0033180)
0.1 1.0 GO:0008180 COP9 signalosome(GO:0008180)
0.1 0.6 GO:0030897 HOPS complex(GO:0030897)
0.1 9.2 GO:0005884 actin filament(GO:0005884)
0.1 0.8 GO:0019773 proteasome core complex, alpha-subunit complex(GO:0019773)
0.1 0.5 GO:0042622 photoreceptor outer segment membrane(GO:0042622)
0.1 0.9 GO:0005751 mitochondrial respiratory chain complex IV(GO:0005751)
0.1 0.3 GO:0071986 Ragulator complex(GO:0071986)
0.0 1.6 GO:0030964 mitochondrial respiratory chain complex I(GO:0005747) NADH dehydrogenase complex(GO:0030964) respiratory chain complex I(GO:0045271)
0.0 0.4 GO:0016602 CCAAT-binding factor complex(GO:0016602)
0.0 1.3 GO:0043679 axon terminus(GO:0043679)
0.0 2.0 GO:0005793 endoplasmic reticulum-Golgi intermediate compartment(GO:0005793)
0.0 0.4 GO:0005956 protein kinase CK2 complex(GO:0005956)
0.0 1.3 GO:0032281 AMPA glutamate receptor complex(GO:0032281)
0.0 0.3 GO:0098982 GABA-ergic synapse(GO:0098982)
0.0 1.2 GO:0022627 cytosolic small ribosomal subunit(GO:0022627)
0.0 2.4 GO:0055037 recycling endosome(GO:0055037)
0.0 1.1 GO:0000307 cyclin-dependent protein kinase holoenzyme complex(GO:0000307)
0.0 5.4 GO:0005743 mitochondrial inner membrane(GO:0005743)
0.0 0.7 GO:0005940 septin ring(GO:0005940) septin complex(GO:0031105) septin cytoskeleton(GO:0032156)
0.0 0.3 GO:0030315 T-tubule(GO:0030315)
0.0 0.1 GO:0034448 EGO complex(GO:0034448) Gtr1-Gtr2 GTPase complex(GO:1990131)
0.0 0.3 GO:0031430 M band(GO:0031430)
0.0 1.0 GO:0022625 cytosolic large ribosomal subunit(GO:0022625)
0.0 1.1 GO:0048786 presynaptic active zone(GO:0048786)
0.0 0.2 GO:0044224 juxtaparanode region of axon(GO:0044224)
0.0 0.2 GO:0005832 chaperonin-containing T-complex(GO:0005832)
0.0 0.5 GO:0048770 melanosome(GO:0042470) pigment granule(GO:0048770)
0.0 0.2 GO:0005885 Arp2/3 protein complex(GO:0005885)
0.0 0.2 GO:0005868 cytoplasmic dynein complex(GO:0005868)
0.0 4.3 GO:0031012 extracellular matrix(GO:0031012)
0.0 1.2 GO:0005741 mitochondrial outer membrane(GO:0005741)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 4.5 GO:0031720 haptoglobin binding(GO:0031720)
0.3 1.4 GO:0031769 glucagon receptor binding(GO:0031769)
0.3 1.2 GO:0017153 sodium:dicarboxylate symporter activity(GO:0017153)
0.3 0.9 GO:0038046 enkephalin receptor activity(GO:0038046)
0.3 1.0 GO:0047035 testosterone dehydrogenase (NAD+) activity(GO:0047035)
0.2 1.1 GO:0048763 ryanodine-sensitive calcium-release channel activity(GO:0005219) calcium-induced calcium release activity(GO:0048763)
0.2 1.2 GO:0033781 cholesterol 24-hydroxylase activity(GO:0033781)
0.2 2.4 GO:0001530 lipopolysaccharide binding(GO:0001530)
0.2 0.6 GO:0048403 brain-derived neurotrophic factor binding(GO:0048403) brain-derived neurotrophic factor-activated receptor activity(GO:0060175)
0.2 1.5 GO:0052650 NADP-retinol dehydrogenase activity(GO:0052650)
0.2 1.2 GO:0070181 small ribosomal subunit rRNA binding(GO:0070181)
0.2 5.7 GO:0016769 transferase activity, transferring nitrogenous groups(GO:0016769)
0.2 1.2 GO:0016416 carnitine O-palmitoyltransferase activity(GO:0004095) O-palmitoyltransferase activity(GO:0016416)
0.2 1.7 GO:0000774 adenyl-nucleotide exchange factor activity(GO:0000774)
0.2 0.8 GO:0051903 alcohol dehydrogenase activity, zinc-dependent(GO:0004024) S-(hydroxymethyl)glutathione dehydrogenase activity(GO:0051903)
0.1 5.1 GO:0005518 collagen binding(GO:0005518)
0.1 0.4 GO:0005502 11-cis retinal binding(GO:0005502)
0.1 0.5 GO:0004998 transferrin receptor activity(GO:0004998)
0.1 0.6 GO:0090554 phospholipid-translocating ATPase activity(GO:0004012) phosphatidylcholine-translocating ATPase activity(GO:0090554) phosphatidylserine-translocating ATPase activity(GO:0090556)
0.1 0.5 GO:0008442 3-hydroxyisobutyrate dehydrogenase activity(GO:0008442)
0.1 1.3 GO:0031628 opioid receptor binding(GO:0031628)
0.1 0.7 GO:0055056 D-glucose transmembrane transporter activity(GO:0055056)
0.1 1.0 GO:0032036 myosin heavy chain binding(GO:0032036)
0.1 1.3 GO:0004971 AMPA glutamate receptor activity(GO:0004971)
0.1 1.1 GO:0061575 cyclin-dependent protein serine/threonine kinase activator activity(GO:0061575)
0.1 0.5 GO:0019136 deoxynucleoside kinase activity(GO:0019136)
0.1 0.5 GO:0004960 thromboxane receptor activity(GO:0004960)
0.1 1.8 GO:0047617 acyl-CoA hydrolase activity(GO:0047617)
0.1 1.2 GO:0048495 Roundabout binding(GO:0048495)
0.1 0.9 GO:0008199 ferric iron binding(GO:0008199)
0.1 5.5 GO:0005212 structural constituent of eye lens(GO:0005212)
0.1 9.2 GO:0042803 protein homodimerization activity(GO:0042803)
0.1 1.0 GO:0044183 protein binding involved in protein folding(GO:0044183)
0.1 0.3 GO:0038132 neuregulin receptor activity(GO:0038131) neuregulin binding(GO:0038132)
0.0 0.6 GO:0030368 interleukin-17 receptor activity(GO:0030368)
0.0 0.9 GO:0050811 GABA receptor binding(GO:0050811)
0.0 0.2 GO:0005031 tumor necrosis factor-activated receptor activity(GO:0005031)
0.0 0.5 GO:0047555 3',5'-cyclic-GMP phosphodiesterase activity(GO:0047555)
0.0 1.0 GO:0008519 ammonium transmembrane transporter activity(GO:0008519)
0.0 1.4 GO:0015459 potassium channel regulator activity(GO:0015459)
0.0 0.4 GO:0052795 exo-alpha-(2->3)-sialidase activity(GO:0052794) exo-alpha-(2->6)-sialidase activity(GO:0052795) exo-alpha-(2->8)-sialidase activity(GO:0052796)
0.0 1.5 GO:0003746 translation elongation factor activity(GO:0003746)
0.0 0.9 GO:0004129 cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors(GO:0016675) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676)
0.0 0.5 GO:0048018 receptor activator activity(GO:0030546) receptor agonist activity(GO:0048018)
0.0 0.6 GO:0015279 store-operated calcium channel activity(GO:0015279)
0.0 0.9 GO:0004869 cysteine-type endopeptidase inhibitor activity(GO:0004869)
0.0 0.1 GO:0010852 cyclase inhibitor activity(GO:0010852) guanylate cyclase inhibitor activity(GO:0030251)
0.0 0.4 GO:0070403 NAD+ binding(GO:0070403)
0.0 0.4 GO:0033691 sialic acid binding(GO:0033691)
0.0 0.5 GO:0017017 MAP kinase tyrosine/serine/threonine phosphatase activity(GO:0017017) MAP kinase phosphatase activity(GO:0033549)
0.0 1.2 GO:0042826 histone deacetylase binding(GO:0042826)
0.0 0.5 GO:0016876 aminoacyl-tRNA ligase activity(GO:0004812) ligase activity, forming carbon-oxygen bonds(GO:0016875) ligase activity, forming aminoacyl-tRNA and related compounds(GO:0016876)
0.0 0.8 GO:0005109 frizzled binding(GO:0005109)
0.0 0.3 GO:0070001 aspartic-type endopeptidase activity(GO:0004190) aspartic-type peptidase activity(GO:0070001)
0.0 3.2 GO:0003735 structural constituent of ribosome(GO:0003735)
0.0 0.3 GO:0098882 structural constituent of presynaptic active zone(GO:0098882)
0.0 2.3 GO:0004222 metalloendopeptidase activity(GO:0004222)
0.0 0.3 GO:0000062 fatty-acyl-CoA binding(GO:0000062)
0.0 0.8 GO:0008009 chemokine activity(GO:0008009)
0.0 0.2 GO:0004169 dolichyl-phosphate-mannose-protein mannosyltransferase activity(GO:0004169)
0.0 0.1 GO:0008430 selenium binding(GO:0008430)
0.0 4.9 GO:0046983 protein dimerization activity(GO:0046983)
0.0 1.1 GO:0045296 cadherin binding(GO:0045296)
0.0 0.5 GO:0016493 C-C chemokine receptor activity(GO:0016493)
0.0 1.0 GO:0001227 transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001227)
0.0 0.4 GO:0016620 oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor(GO:0016620)
0.0 0.3 GO:0004198 calcium-dependent cysteine-type endopeptidase activity(GO:0004198)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 4.1 PID INTEGRIN2 PATHWAY Beta2 integrin cell surface interactions
0.0 1.2 PID GLYPICAN 1PATHWAY Glypican 1 network
0.0 1.6 NABA COLLAGENS Genes encoding collagen proteins
0.0 1.7 PID HNF3B PATHWAY FOXA2 and FOXA3 transcription factor networks
0.0 0.2 SA FAS SIGNALING The TNF-type receptor Fas induces apoptosis on ligand binding.
0.0 1.1 PID MYC REPRESS PATHWAY Validated targets of C-MYC transcriptional repression
0.0 0.3 PID WNT SIGNALING PATHWAY Wnt signaling network

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 1.7 REACTOME INSULIN RECEPTOR RECYCLING Genes involved in Insulin receptor recycling
0.2 3.9 REACTOME AMYLOIDS Genes involved in Amyloids
0.1 1.3 REACTOME PURINE RIBONUCLEOSIDE MONOPHOSPHATE BIOSYNTHESIS Genes involved in Purine ribonucleoside monophosphate biosynthesis
0.1 0.4 REACTOME OPSINS Genes involved in Opsins
0.0 0.6 REACTOME SYNTHESIS OF PE Genes involved in Synthesis of PE
0.0 0.4 REACTOME PYRIMIDINE CATABOLISM Genes involved in Pyrimidine catabolism
0.0 0.4 REACTOME ACTIVATION OF CHAPERONE GENES BY ATF6 ALPHA Genes involved in Activation of Chaperone Genes by ATF6-alpha
0.0 1.6 REACTOME NCAM1 INTERACTIONS Genes involved in NCAM1 interactions
0.0 7.0 REACTOME METABOLISM OF AMINO ACIDS AND DERIVATIVES Genes involved in Metabolism of amino acids and derivatives
0.0 4.2 REACTOME PEPTIDE CHAIN ELONGATION Genes involved in Peptide chain elongation
0.0 2.0 REACTOME RESPIRATORY ELECTRON TRANSPORT Genes involved in Respiratory electron transport
0.0 0.5 REACTOME BILE SALT AND ORGANIC ANION SLC TRANSPORTERS Genes involved in Bile salt and organic anion SLC transporters
0.0 1.2 REACTOME NETRIN1 SIGNALING Genes involved in Netrin-1 signaling
0.0 0.2 REACTOME EXTRINSIC PATHWAY FOR APOPTOSIS Genes involved in Extrinsic Pathway for Apoptosis
0.0 0.5 REACTOME MITOCHONDRIAL TRNA AMINOACYLATION Genes involved in Mitochondrial tRNA aminoacylation
0.0 0.3 REACTOME METABOLISM OF PORPHYRINS Genes involved in Metabolism of porphyrins
0.0 0.6 REACTOME O LINKED GLYCOSYLATION OF MUCINS Genes involved in O-linked glycosylation of mucins
0.0 0.1 REACTOME PLATELET ADHESION TO EXPOSED COLLAGEN Genes involved in Platelet Adhesion to exposed collagen
0.0 0.1 REACTOME SIGNALLING TO P38 VIA RIT AND RIN Genes involved in Signalling to p38 via RIT and RIN
0.0 1.3 REACTOME SIGNALING BY RHO GTPASES Genes involved in Signaling by Rho GTPases
0.0 0.2 REACTOME SYNTHESIS OF SUBSTRATES IN N GLYCAN BIOSYTHESIS Genes involved in Synthesis of substrates in N-glycan biosythesis