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PRJNA195909:zebrafish embryo and larva development
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Results for nr4a2b
Z-value: 1.40
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Transcription factors associated with nr4a2b
Activity-expression correlation:
| Gene | Promoter | Pearson corr. coef. | P-value | Plot |
|---|---|---|---|---|
| nr4a2b | dr11_v1_chr6_+_12462079_12462079 | 0.42 | 2.6e-01 | Click! |
| Promoter | Log-likelihood | Transcript | Gene | Gene Info |
|---|---|---|---|---|
| chr1_+_19332837 Show fit | 3.67 |
ENSDART00000078594
|
tyrosinase-related protein 1b |
|
| chr10_+_9561066 Show fit | 3.34 |
ENSDART00000136281
|
si:ch211-243g18.2 |
|
| chr20_-_10120442 Show fit | 3.29 |
ENSDART00000144970
|
Meis homeobox 2b |
|
| chr17_+_7595356 Show fit | 3.12 |
ENSDART00000130625
|
si:dkeyp-110a12.4 |
|
| chr19_-_5332784 Show fit | 2.99 |
ENSDART00000010373
|
keratin, type 1, gene 19d |
|
| chr5_+_1278092 Show fit | 2.87 |
ENSDART00000147972
ENSDART00000159783 |
dynamin 1a |
|
| chr16_+_23972126 Show fit | 2.70 |
ENSDART00000132742
ENSDART00000145330 |
apolipoprotein C-I |
|
| chr3_+_23687909 Show fit | 2.53 |
ENSDART00000046638
|
homeobox B8a |
|
| chr7_+_25913225 Show fit | 2.48 |
ENSDART00000129924
|
high mobility group box 3a |
|
| chr23_-_24488696 Show fit | 2.35 |
ENSDART00000155593
|
transmembrane protein 82 |
Network of associatons between targets according to the STRING database.
First level regulatory network of nr4a2b
Gene Ontology Analysis
Gene overrepresentation in biological process category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.3 | 4.5 | GO:0003209 | cardiac atrium morphogenesis(GO:0003209) |
| 0.7 | 3.7 | GO:0097066 | response to thyroid hormone(GO:0097066) |
| 0.1 | 3.4 | GO:0033627 | cell adhesion mediated by integrin(GO:0033627) |
| 0.3 | 3.1 | GO:0006007 | glucose catabolic process(GO:0006007) NADH regeneration(GO:0006735) glycolytic process through fructose-6-phosphate(GO:0061615) glycolytic process through glucose-6-phosphate(GO:0061620) canonical glycolysis(GO:0061621) glucose catabolic process to pyruvate(GO:0061718) |
| 0.0 | 3.1 | GO:1990266 | neutrophil migration(GO:1990266) |
| 0.9 | 2.7 | GO:0050995 | negative regulation of lipid transport(GO:0032369) negative regulation of lipid catabolic process(GO:0050995) |
| 0.1 | 2.5 | GO:0048920 | posterior lateral line neuromast primordium migration(GO:0048920) |
| 0.1 | 2.1 | GO:0015693 | magnesium ion transport(GO:0015693) |
| 0.1 | 2.1 | GO:0098884 | postsynaptic neurotransmitter receptor internalization(GO:0098884) |
| 0.2 | 2.0 | GO:0006285 | base-excision repair, AP site formation(GO:0006285) |
Gene overrepresentation in cellular component category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.1 | 6.3 | GO:0005882 | intermediate filament(GO:0005882) |
| 0.3 | 3.7 | GO:0033162 | melanosome membrane(GO:0033162) chitosome(GO:0045009) |
| 0.1 | 3.4 | GO:0008305 | integrin complex(GO:0008305) |
| 0.0 | 3.4 | GO:0016324 | apical plasma membrane(GO:0016324) |
| 0.3 | 3.1 | GO:0005945 | 6-phosphofructokinase complex(GO:0005945) |
| 0.2 | 2.7 | GO:0034361 | very-low-density lipoprotein particle(GO:0034361) |
| 0.2 | 2.1 | GO:0008250 | oligosaccharyltransferase complex(GO:0008250) |
| 0.1 | 2.1 | GO:0098844 | postsynaptic endocytic zone membrane(GO:0098844) |
| 0.1 | 2.1 | GO:0033017 | sarcoplasmic reticulum membrane(GO:0033017) |
| 0.1 | 1.9 | GO:0031430 | M band(GO:0031430) |
Gene overrepresentation in molecular function category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 6.3 | GO:0005198 | structural molecule activity(GO:0005198) |
| 0.0 | 4.6 | GO:0005201 | extracellular matrix structural constituent(GO:0005201) |
| 0.1 | 3.4 | GO:0005178 | integrin binding(GO:0005178) |
| 0.3 | 3.1 | GO:0003872 | 6-phosphofructokinase activity(GO:0003872) |
| 0.2 | 2.7 | GO:0004859 | phospholipase inhibitor activity(GO:0004859) lipase inhibitor activity(GO:0055102) |
| 0.1 | 2.5 | GO:0008301 | DNA binding, bending(GO:0008301) |
| 0.2 | 2.0 | GO:0000700 | mismatch base pair DNA N-glycosylase activity(GO:0000700) pyrimidine-specific mismatch base pair DNA N-glycosylase activity(GO:0008263) |
| 0.2 | 1.8 | GO:0015250 | water channel activity(GO:0015250) |
| 0.1 | 1.6 | GO:0008137 | NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136) |
| 0.1 | 1.5 | GO:0004806 | triglyceride lipase activity(GO:0004806) |
Gene overrepresentation in curated gene sets: canonical pathways category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.1 | 1.6 | PID INTEGRIN4 PATHWAY | Alpha6 beta4 integrin-ligand interactions |
| 0.0 | 1.0 | NABA COLLAGENS | Genes encoding collagen proteins |
| 0.0 | 0.9 | NABA ECM AFFILIATED | Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins |
| 0.0 | 0.8 | PID HDAC CLASSI PATHWAY | Signaling events mediated by HDAC Class I |
Gene overrepresentation in curated gene sets: REACTOME pathways category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 2.1 | REACTOME ASPARAGINE N LINKED GLYCOSYLATION | Genes involved in Asparagine N-linked glycosylation |
| 0.0 | 1.6 | REACTOME CELL JUNCTION ORGANIZATION | Genes involved in Cell junction organization |
| 0.0 | 1.6 | REACTOME RESPIRATORY ELECTRON TRANSPORT | Genes involved in Respiratory electron transport |
| 0.0 | 1.0 | REACTOME COLLAGEN FORMATION | Genes involved in Collagen formation |
| 0.0 | 0.8 | REACTOME NOTCH1 INTRACELLULAR DOMAIN REGULATES TRANSCRIPTION | Genes involved in NOTCH1 Intracellular Domain Regulates Transcription |
| 0.0 | 0.5 | REACTOME GLUCONEOGENESIS | Genes involved in Gluconeogenesis |
| 0.0 | 0.3 | REACTOME CREATION OF C4 AND C2 ACTIVATORS | Genes involved in Creation of C4 and C2 activators |
| 0.0 | 0.3 | REACTOME CITRIC ACID CYCLE TCA CYCLE | Genes involved in Citric acid cycle (TCA cycle) |
| 0.0 | 0.3 | REACTOME LIGAND GATED ION CHANNEL TRANSPORT | Genes involved in Ligand-gated ion channel transport |
| 0.0 | 0.2 | REACTOME PROTEOLYTIC CLEAVAGE OF SNARE COMPLEX PROTEINS | Genes involved in Proteolytic cleavage of SNARE complex proteins |