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PRJNA195909:zebrafish embryo and larva development

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Results for nr4a2b

Z-value: 1.40

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Transcription factors associated with nr4a2b

Gene Symbol Gene ID Gene Info
ENSDARG00000044532 nuclear receptor subfamily 4, group A, member 2b

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
nr4a2bdr11_v1_chr6_+_12462079_124620790.422.6e-01Click!

Activity profile of nr4a2b motif

Sorted Z-values of nr4a2b motif

Promoter Log-likelihood Transcript Gene Gene Info
chr1_+_19332837 3.67 ENSDART00000078594
tyrosinase-related protein 1b
chr10_+_9561066 3.34 ENSDART00000136281
si:ch211-243g18.2
chr20_-_10120442 3.29 ENSDART00000144970
Meis homeobox 2b
chr17_+_7595356 3.12 ENSDART00000130625
si:dkeyp-110a12.4
chr19_-_5332784 2.99 ENSDART00000010373
keratin, type 1, gene 19d
chr5_+_1278092 2.87 ENSDART00000147972
ENSDART00000159783
dynamin 1a
chr16_+_23972126 2.70 ENSDART00000132742
ENSDART00000145330
apolipoprotein C-I
chr3_+_23687909 2.53 ENSDART00000046638
homeobox B8a
chr7_+_25913225 2.48 ENSDART00000129924
high mobility group box 3a
chr23_-_24488696 2.35 ENSDART00000155593
transmembrane protein 82
chr1_+_16127825 2.12 ENSDART00000122503
tumor suppressor candidate 3
chr20_+_40150612 2.07 ENSDART00000143680
ENSDART00000109681
ENSDART00000101041
ENSDART00000121818
triadin
chr25_+_18964782 2.01 ENSDART00000017299
thymine DNA glycosylase, tandem duplicate 1
chr23_+_36063599 2.01 ENSDART00000103147
homeobox C12a
chr5_-_41831646 1.97 ENSDART00000134326
si:dkey-65b12.6
chr8_+_39634114 1.97 ENSDART00000144293
musashi RNA-binding protein 1
chr14_-_17121676 1.89 ENSDART00000170154
ENSDART00000060479
smoothelin-like 1
chr3_-_46818001 1.88 ENSDART00000166505
ELAV like neuron-specific RNA binding protein 3
chr11_+_11201096 1.88 ENSDART00000171916
ENSDART00000171521
ENSDART00000087105
ENSDART00000159603
myomesin 2a
chr9_+_31795343 1.86 ENSDART00000139584
integrin, beta-like 1
chr3_-_46817838 1.84 ENSDART00000028610
ELAV like neuron-specific RNA binding protein 3
chr6_-_39764995 1.82 ENSDART00000085277
phosphofructokinase, muscle b
chr23_+_27068225 1.81 ENSDART00000054238
major intrinsic protein of lens fiber a
chr7_-_24046999 1.74 ENSDART00000144616
ENSDART00000124653
ENSDART00000127813
dehydrogenase/reductase (SDR family) member 4
chr8_+_13106760 1.58 ENSDART00000029308
integrin, beta 4
chr7_-_19146925 1.49 ENSDART00000142924
ENSDART00000009695
kirre like nephrin family adhesion molecule 1a
chr4_+_16795688 1.37 ENSDART00000132337
spexin hormone
chr4_-_4932619 1.35 ENSDART00000103293
NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 5
chr15_-_16884912 1.30 ENSDART00000062135
zgc:103681
chr5_+_37087583 1.27 ENSDART00000049900
transgelin 2
chr9_-_21067971 1.27 ENSDART00000004333
T-box 15
chr6_-_39765546 1.27 ENSDART00000185767
phosphofructokinase, muscle b
chr3_+_23710839 1.27 ENSDART00000151584
homeobox B4a
chr14_+_33882973 1.25 ENSDART00000019396
chloride intracellular channel 2
chr3_-_22212764 1.23 ENSDART00000155490
microtubule-associated protein tau b
chr3_-_28258462 1.23 ENSDART00000191573
RNA binding fox-1 homolog 1
chr15_-_21239416 1.23 ENSDART00000155787
si:dkey-105h12.2
chr6_-_10835849 1.23 ENSDART00000005903
ENSDART00000135065
ATP synthase membrane subunit c locus 3b
chr6_-_35738836 1.22 ENSDART00000111642
bone morphogenetic protein/retinoic acid inducible neural-specific 3a, tandem duplicate 1
chr7_+_31871830 1.21 ENSDART00000139899
myosin binding protein C, cardiac
chr17_-_12389259 1.17 ENSDART00000185724
synaptosomal-associated protein, 25b
chr3_+_32553714 1.09 ENSDART00000165638
paired box 10
chr11_+_2172335 1.07 ENSDART00000170593
homeobox C12b
chr5_-_41838354 1.06 ENSDART00000146793
si:dkey-65b12.6
chr25_-_16969922 1.05 ENSDART00000111158
tp53-induced glycolysis and apoptosis regulator a
chr6_-_21189295 1.02 ENSDART00000137136
obscurin-like 1a
chr1_-_51734524 1.00 ENSDART00000109640
ENSDART00000122628
JunB proto-oncogene, AP-1 transcription factor subunit a
chr23_-_45504991 0.98 ENSDART00000148761
collagen type XXIV alpha 1
chr2_+_6885852 0.98 ENSDART00000016607
regulator of G protein signaling 5b
chr12_+_36891483 0.94 ENSDART00000048927
COX10 heme A:farnesyltransferase cytochrome c oxidase assembly factor
chr6_+_40775800 0.87 ENSDART00000085090
si:ch211-157b11.8
chr24_+_25471196 0.86 ENSDART00000066625
small muscle protein, X-linked
chr8_-_7440364 0.84 ENSDART00000180659
histone deacetylase 6
chr10_-_20524592 0.84 ENSDART00000185048
DDHD domain containing 2
chr18_+_13182528 0.80 ENSDART00000166298
zgc:56622
chr1_-_30689004 0.77 ENSDART00000018827
dachshund c
chr8_-_23578660 0.77 ENSDART00000039080
Wiskott-Aldrich syndrome (eczema-thrombocytopenia) b
chr5_-_16983336 0.75 ENSDART00000038740
polypeptide N-acetylgalactosaminyltransferase 9
chr12_-_26423439 0.75 ENSDART00000113978
synaptopodin 2-like b
chr10_-_29892486 0.75 ENSDART00000099983
brain-specific homeobox
chr7_+_20524064 0.75 ENSDART00000052917
solute carrier family 3 (amino acid transporter heavy chain), member 2a
chr18_-_15771551 0.74 ENSDART00000130931
ENSDART00000154079
si:ch211-219a15.3
chr15_+_29292154 0.72 ENSDART00000137817
RAP1 GTPase activating protein 2a
chr1_+_31638274 0.71 ENSDART00000057885
fibroblast growth factor 8 b
chr15_+_20403903 0.70 ENSDART00000134182
cytochrome c oxidase subunit VIIa polypeptide 1 (muscle)
chr19_-_34927201 0.70 ENSDART00000076518
Src-like-adaptor 1
chr11_+_1409622 0.65 ENSDART00000157042
protein phosphatase 1, regulatory subunit 3Db
chr3_+_31177972 0.65 ENSDART00000185954
C-type lectin domain containing 19A
chr5_-_67721368 0.65 ENSDART00000134386
Rho GTPase activating protein 31
chr19_-_703898 0.64 ENSDART00000181096
ENSDART00000121462
solute carrier family 6 (neutral amino acid transporter), member 19a, tandem duplicate 2
chr19_+_32158010 0.64 ENSDART00000005255
mitochondrial ribosomal protein L53
chr3_+_24190207 0.62 ENSDART00000034762
proline rich 15-like a
chr10_-_20524387 0.62 ENSDART00000159060
DDHD domain containing 2
chr6_-_50404732 0.62 ENSDART00000055510
reactive oxygen species modulator 1
chr6_+_29288223 0.62 ENSDART00000112099
zgc:172121
chr6_-_29288155 0.61 ENSDART00000078630
NME/NM23 family member 7
chr1_-_20593778 0.60 ENSDART00000124770
UDP glycosyltransferase 8
chr23_+_21544227 0.59 ENSDART00000140253
Rho guanine nucleotide exchange factor (GEF) 10-like b
chr24_-_36802891 0.56 ENSDART00000088130
dephospho-CoA kinase domain containing
chr10_-_11385155 0.56 ENSDART00000064214
placenta-specific 8, tandem duplicate 1
chr16_+_20161805 0.55 ENSDART00000192146
chromosome 16 C2orf66 homolog
chr17_+_30545895 0.55 ENSDART00000076739
NHS-like 1a
chr5_-_41841892 0.54 ENSDART00000167089
si:dkey-65b12.6
chr8_-_14052349 0.53 ENSDART00000135811
ATPase plasma membrane Ca2+ transporting 3a
chr6_-_10320676 0.53 ENSDART00000151247
sodium channel, voltage-gated, type I like, alpha b
chr17_-_17764801 0.51 ENSDART00000155261
SRA stem-loop interacting RNA binding protein
chr3_+_17806213 0.49 ENSDART00000055890
zinc finger protein 385C
chr5_-_68093169 0.49 ENSDART00000051849
solute carrier family 25 (mitochondrial carrier; oxoglutarate carrier), member 11
chr8_-_42238543 0.48 ENSDART00000062697
GDNF family receptor alpha 2a
chr20_+_106481 0.48 ENSDART00000148834
si:ch1073-155h21.2
chr14_+_35023923 0.47 ENSDART00000172171
early B cell factor 3a
chr8_-_979735 0.46 ENSDART00000149612
zinc finger protein 366
chr13_-_41155472 0.46 ENSDART00000160588
si:dkeyp-86d6.2
chr7_+_34620418 0.45 ENSDART00000081338
solute carrier family 9, subfamily A (NHE5, cation proton antiporter 5), member 5
chr12_-_26415499 0.44 ENSDART00000185779
synaptopodin 2-like b
chr23_+_26142807 0.44 ENSDART00000158878
protein tyrosine phosphatase, non-receptor type 22
chr7_+_44484853 0.43 ENSDART00000189079
ENSDART00000121826
brain expressed, associated with NEDD4, 1
chr24_+_22022109 0.42 ENSDART00000133686
rhophilin associated tail protein 1-like
chr18_+_31410652 0.40 ENSDART00000098504
differentially expressed in FDCP 8 homolog (mouse)
chr13_-_27660955 0.40 ENSDART00000188651
ENSDART00000134494
regulating synaptic membrane exocytosis 1a
chr5_-_66301142 0.39 ENSDART00000067541
prolactin receptor b
chr6_+_29288006 0.38 ENSDART00000043496
zgc:172121
chr23_-_28141419 0.37 ENSDART00000133039
tachykinin 3a
chr2_-_48753873 0.35 ENSDART00000189556

chr21_+_5080789 0.33 ENSDART00000024199
ATP synthase F1 subunit alpha
chr9_+_42066030 0.33 ENSDART00000185311
ENSDART00000015267
poly(rC) binding protein 3
chr20_-_1151265 0.33 ENSDART00000012376
gamma-aminobutyric acid (GABA) A receptor, rho 1
chr11_+_23810148 0.32 ENSDART00000127846
neurofascin homolog (chicken) a
chr22_+_31821815 0.31 ENSDART00000159825
dedicator of cytokinesis 3
chr8_-_44004135 0.31 ENSDART00000136269
RIMS binding protein 2
chr5_-_63218919 0.30 ENSDART00000149979
tectorin alpha
chr7_-_24005268 0.30 ENSDART00000173608
si:dkey-183c6.9
chr1_+_44826593 0.29 ENSDART00000162200
zgc:165520
chr2_-_32457919 0.29 ENSDART00000132792
ENSDART00000041319
solute carrier family 4 (anion exchanger), member 2a
chr18_-_2433011 0.28 ENSDART00000181922
ENSDART00000193276

chr24_+_34089977 0.27 ENSDART00000157466
ankyrin repeat and SOCS box containing 10
chr7_+_38588866 0.27 ENSDART00000015682
NADH dehydrogenase (ubiquinone) Fe-S protein 3, (NADH-coenzyme Q reductase)
chr21_-_22724980 0.27 ENSDART00000035469
complement component 1, q subcomponent, A chain
chr12_-_47648538 0.26 ENSDART00000108477
fumarate hydratase
chr2_-_11912347 0.25 ENSDART00000023851
abhydrolase domain containing 3
chr11_-_21363834 0.23 ENSDART00000080051
si:dkey-85p17.3
chr23_+_26142613 0.21 ENSDART00000165046
protein tyrosine phosphatase, non-receptor type 22
chr15_+_31526225 0.20 ENSDART00000154456
WD40 repeat domain 95
chr4_-_18434924 0.20 ENSDART00000190271
suppressor of cytokine signaling 2
chr16_-_35586401 0.20 ENSDART00000169868
ENSDART00000166606
ENSDART00000162562
Scm polycomb group protein homolog 1
chr14_+_36628131 0.19 ENSDART00000188625
ENSDART00000125345
si:dkey-237h12.3
chr15_+_11840311 0.19 ENSDART00000167671
protein kinase D2
chr15_+_1705167 0.18 ENSDART00000081940
otolin 1b
chr4_-_18775548 0.18 ENSDART00000141187
differentially expressed in FDCP 6c homolog
chr23_+_21638258 0.18 ENSDART00000104188
immunoglobin superfamily, member 21b
chr13_+_7241170 0.17 ENSDART00000109434
apoptosis-inducing factor, mitochondrion-associated, 2
chr2_-_44971551 0.17 ENSDART00000018818
mitochondrial E3 ubiquitin protein ligase 1a
chr8_-_8698607 0.17 ENSDART00000046712
zgc:86609
chr12_-_29305220 0.17 ENSDART00000153458
SH2 domain containing 4Bb
chr18_+_9382847 0.16 ENSDART00000061886
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3Ab
chr2_-_3045861 0.16 ENSDART00000105818
ENSDART00000187575
guanylate kinase 1a
chr5_-_33959868 0.13 ENSDART00000143652
zgc:63972
chr2_-_38282079 0.13 ENSDART00000145808
si:ch211-10e2.1
chr18_-_4957022 0.12 ENSDART00000101686
zinc finger, B-box domain containing
chr20_-_45722895 0.11 ENSDART00000153273
glycerophosphocholine phosphodiesterase 1
chr7_+_22702437 0.11 ENSDART00000182054
si:dkey-165a24.9
chr20_-_26937453 0.10 ENSDART00000139756
finTRIM family, member 97
chr1_+_54115839 0.09 ENSDART00000180214

chr16_-_16619854 0.09 ENSDART00000150512
ENSDART00000191306
ENSDART00000181773
ENSDART00000183231
cytochrome P450, family 21, subfamily A, polypeptide 2
chr24_-_24848612 0.08 ENSDART00000190941
corticotropin releasing hormone b
chr1_-_53988017 0.08 ENSDART00000003097
si:ch211-133l11.10
chr3_-_25377163 0.07 ENSDART00000055490
karyopherin alpha 2 (RAG cohort 1, importin alpha 1)
chr19_+_14059349 0.07 ENSDART00000166230
trophoblast glycoprotein a
chr16_-_22294265 0.07 ENSDART00000124718
aquaporin 10a
chr8_-_17997845 0.06 ENSDART00000121660
acyl-CoA thioesterase 11b
chr10_+_36354863 0.06 ENSDART00000159675
odorant receptor, family C, subfamily 104, member 1
chr13_+_21768447 0.06 ENSDART00000100941
coiled-coil-helix-coiled-coil-helix domain containing 1
chr10_+_41668483 0.05 ENSDART00000127073
leucine rich repeat containing 75Bb
chr15_-_11341635 0.05 ENSDART00000055220
RAB30, member RAS oncogene family
chr8_+_53120278 0.05 ENSDART00000125232
nuclear receptor subfamily 2, group C, member 2
chr7_+_22702225 0.04 ENSDART00000173672
si:dkey-165a24.9
chr16_-_16761164 0.01 ENSDART00000135872
si:dkey-27n14.1
chr21_+_37411547 0.00 ENSDART00000076320
mitochondrial ribosomal protein S17

Network of associatons between targets according to the STRING database.

First level regulatory network of nr4a2b

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.9 2.7 GO:0050995 negative regulation of lipid transport(GO:0032369) negative regulation of lipid catabolic process(GO:0050995)
0.7 3.7 GO:0097066 response to thyroid hormone(GO:0097066)
0.5 1.4 GO:0045987 positive regulation of smooth muscle contraction(GO:0045987)
0.4 1.6 GO:0030811 regulation of glycolytic process(GO:0006110) regulation of nucleotide catabolic process(GO:0030811) regulation of cofactor metabolic process(GO:0051193) regulation of coenzyme metabolic process(GO:0051196)
0.3 4.5 GO:0003209 cardiac atrium morphogenesis(GO:0003209)
0.3 3.1 GO:0006007 glucose catabolic process(GO:0006007) NADH regeneration(GO:0006735) glycolytic process through fructose-6-phosphate(GO:0061615) glycolytic process through glucose-6-phosphate(GO:0061620) canonical glycolysis(GO:0061621) glucose catabolic process to pyruvate(GO:0061718)
0.2 0.2 GO:0051792 medium-chain fatty acid biosynthetic process(GO:0051792)
0.2 1.8 GO:0006833 water transport(GO:0006833)
0.2 1.2 GO:0038065 collagen-activated tyrosine kinase receptor signaling pathway(GO:0038063) collagen-activated signaling pathway(GO:0038065)
0.2 2.0 GO:0006285 base-excision repair, AP site formation(GO:0006285)
0.1 2.1 GO:0015693 magnesium ion transport(GO:0015693)
0.1 0.6 GO:2000379 protein import into mitochondrial inner membrane(GO:0045039) positive regulation of reactive oxygen species metabolic process(GO:2000379)
0.1 1.2 GO:0071300 cellular response to retinoic acid(GO:0071300)
0.1 0.7 GO:0097250 mitochondrial respiratory chain supercomplex assembly(GO:0097250)
0.1 2.1 GO:0098884 postsynaptic neurotransmitter receptor internalization(GO:0098884)
0.1 3.4 GO:0033627 cell adhesion mediated by integrin(GO:0033627)
0.1 0.7 GO:0021982 pineal gland development(GO:0021982)
0.1 0.4 GO:0038161 prolactin signaling pathway(GO:0038161)
0.1 0.5 GO:0071422 thiosulfate transport(GO:0015709) oxaloacetate transport(GO:0015729) malate transport(GO:0015743) succinate transport(GO:0015744) succinate transmembrane transport(GO:0071422) malate transmembrane transport(GO:0071423)
0.1 0.9 GO:0045444 fat cell differentiation(GO:0045444)
0.1 1.2 GO:0045162 clustering of voltage-gated sodium channels(GO:0045162)
0.1 0.3 GO:0070316 G0 to G1 transition(GO:0045023) regulation of G0 to G1 transition(GO:0070316) negative regulation of G0 to G1 transition(GO:0070317)
0.1 0.4 GO:0007217 tachykinin receptor signaling pathway(GO:0007217)
0.1 0.5 GO:0070584 mitochondrion morphogenesis(GO:0070584)
0.1 0.7 GO:0060142 regulation of syncytium formation by plasma membrane fusion(GO:0060142)
0.1 1.0 GO:0009086 methionine biosynthetic process(GO:0009086)
0.1 1.6 GO:0015985 energy coupled proton transport, down electrochemical gradient(GO:0015985) ATP synthesis coupled proton transport(GO:0015986)
0.1 2.5 GO:0048920 posterior lateral line neuromast primordium migration(GO:0048920)
0.1 1.8 GO:0032233 positive regulation of actin filament bundle assembly(GO:0032233)
0.1 0.4 GO:0048240 sperm capacitation(GO:0048240)
0.1 0.8 GO:2000601 positive regulation of actin nucleation(GO:0051127) positive regulation of Arp2/3 complex-mediated actin nucleation(GO:2000601)
0.1 0.3 GO:0035889 otolith tethering(GO:0035889)
0.0 0.5 GO:1990118 sodium ion import(GO:0097369) sodium ion import across plasma membrane(GO:0098719) sodium ion import into cell(GO:1990118)
0.0 0.6 GO:0015937 coenzyme A biosynthetic process(GO:0015937)
0.0 0.6 GO:0046051 UTP biosynthetic process(GO:0006228) UTP metabolic process(GO:0046051)
0.0 0.9 GO:0006783 heme biosynthetic process(GO:0006783)
0.0 0.2 GO:0003272 endocardial cushion formation(GO:0003272) protein kinase D signaling(GO:0089700)
0.0 0.7 GO:0005979 regulation of glycogen biosynthetic process(GO:0005979) regulation of glucan biosynthetic process(GO:0010962)
0.0 3.1 GO:1990266 neutrophil migration(GO:1990266)
0.0 0.2 GO:0046426 negative regulation of JAK-STAT cascade(GO:0046426) negative regulation of STAT cascade(GO:1904893)
0.0 0.2 GO:0048755 branching morphogenesis of a nerve(GO:0048755)
0.0 1.2 GO:0021854 hypothalamus development(GO:0021854)
0.0 0.1 GO:0035902 response to immobilization stress(GO:0035902)
0.0 0.3 GO:0006108 malate metabolic process(GO:0006108)
0.0 1.3 GO:0022904 respiratory electron transport chain(GO:0022904)
0.0 0.1 GO:0060829 negative regulation of canonical Wnt signaling pathway involved in neural plate anterior/posterior pattern formation(GO:0060829)
0.0 1.0 GO:0010842 retina layer formation(GO:0010842)
0.0 0.4 GO:2000300 regulation of synaptic vesicle exocytosis(GO:2000300)
0.0 0.6 GO:0035335 peptidyl-tyrosine dephosphorylation(GO:0035335)
0.0 0.3 GO:0007274 neuromuscular synaptic transmission(GO:0007274)
0.0 0.1 GO:0006704 glucocorticoid biosynthetic process(GO:0006704)
0.0 0.3 GO:0015701 bicarbonate transport(GO:0015701)
0.0 0.7 GO:0051781 positive regulation of cell division(GO:0051781)
0.0 0.8 GO:0006476 protein deacetylation(GO:0006476)
0.0 1.5 GO:0021782 glial cell development(GO:0021782)
0.0 0.2 GO:0000266 mitochondrial fission(GO:0000266)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.0 GO:0005592 collagen type XI trimer(GO:0005592)
0.3 3.7 GO:0033162 melanosome membrane(GO:0033162) chitosome(GO:0045009)
0.3 3.1 GO:0005945 6-phosphofructokinase complex(GO:0005945)
0.2 1.2 GO:0070032 synaptobrevin 2-SNAP-25-syntaxin-1a-complexin I complex(GO:0070032)
0.2 2.7 GO:0034361 very-low-density lipoprotein particle(GO:0034361)
0.2 0.9 GO:0043034 costamere(GO:0043034)
0.2 2.1 GO:0008250 oligosaccharyltransferase complex(GO:0008250)
0.1 1.4 GO:0031045 dense core granule(GO:0031045)
0.1 2.1 GO:0098844 postsynaptic endocytic zone membrane(GO:0098844)
0.1 1.9 GO:0031430 M band(GO:0031430)
0.1 2.1 GO:0033017 sarcoplasmic reticulum membrane(GO:0033017)
0.1 1.2 GO:0000276 mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)(GO:0000276)
0.1 3.4 GO:0008305 integrin complex(GO:0008305)
0.1 6.3 GO:0005882 intermediate filament(GO:0005882)
0.1 0.6 GO:0005744 mitochondrial inner membrane presequence translocase complex(GO:0005744)
0.1 0.3 GO:0045261 proton-transporting ATP synthase complex, catalytic core F(1)(GO:0045261)
0.0 0.2 GO:0098651 collagen type IV trimer(GO:0005587) network-forming collagen trimer(GO:0098642) collagen network(GO:0098645) basement membrane collagen trimer(GO:0098651)
0.0 1.9 GO:0031941 filamentous actin(GO:0031941)
0.0 0.7 GO:0000164 protein phosphatase type 1 complex(GO:0000164)
0.0 1.6 GO:0045271 mitochondrial respiratory chain complex I(GO:0005747) NADH dehydrogenase complex(GO:0030964) respiratory chain complex I(GO:0045271)
0.0 1.3 GO:0005637 nuclear inner membrane(GO:0005637)
0.0 3.4 GO:0016324 apical plasma membrane(GO:0016324)
0.0 1.6 GO:0034707 chloride channel complex(GO:0034707)
0.0 0.5 GO:0001518 voltage-gated sodium channel complex(GO:0001518) sodium channel complex(GO:0034706)
0.0 0.7 GO:0005746 mitochondrial respiratory chain(GO:0005746)
0.0 1.5 GO:0030134 ER to Golgi transport vesicle(GO:0030134)
0.0 1.2 GO:0030018 Z disc(GO:0030018)
0.0 0.2 GO:0072546 ER membrane protein complex(GO:0072546)
0.0 0.3 GO:0045239 tricarboxylic acid cycle enzyme complex(GO:0045239)
0.0 0.4 GO:0048788 cytoskeleton of presynaptic active zone(GO:0048788)
0.0 0.2 GO:0031307 integral component of mitochondrial outer membrane(GO:0031307)
0.0 0.8 GO:0005884 actin filament(GO:0005884)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 0.9 GO:0004311 farnesyltranstransferase activity(GO:0004311)
0.3 3.1 GO:0003872 6-phosphofructokinase activity(GO:0003872)
0.3 1.1 GO:0034416 bisphosphoglycerate phosphatase activity(GO:0034416)
0.2 2.0 GO:0000700 mismatch base pair DNA N-glycosylase activity(GO:0000700) pyrimidine-specific mismatch base pair DNA N-glycosylase activity(GO:0008263)
0.2 0.8 GO:0042903 tubulin deacetylase activity(GO:0042903) acetylspermidine deacetylase activity(GO:0047611)
0.2 2.7 GO:0004859 phospholipase inhibitor activity(GO:0004859) lipase inhibitor activity(GO:0055102)
0.2 1.8 GO:0015250 water channel activity(GO:0015250)
0.2 0.8 GO:0004032 alditol:NADP+ 1-oxidoreductase activity(GO:0004032)
0.1 2.5 GO:0008301 DNA binding, bending(GO:0008301)
0.1 0.6 GO:0004726 non-membrane spanning protein tyrosine phosphatase activity(GO:0004726)
0.1 1.2 GO:0032036 myosin heavy chain binding(GO:0032036)
0.1 1.0 GO:0008172 S-methyltransferase activity(GO:0008172)
0.1 0.4 GO:0004925 prolactin receptor activity(GO:0004925)
0.1 0.5 GO:0015140 thiosulfate transmembrane transporter activity(GO:0015117) oxaloacetate transmembrane transporter activity(GO:0015131) malate transmembrane transporter activity(GO:0015140)
0.1 0.7 GO:0005105 type 1 fibroblast growth factor receptor binding(GO:0005105)
0.1 0.2 GO:0008970 phosphatidylcholine 1-acylhydrolase activity(GO:0008970)
0.1 0.3 GO:0070891 lipoteichoic acid binding(GO:0070891)
0.1 1.6 GO:0008137 NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136)
0.1 3.4 GO:0005178 integrin binding(GO:0005178)
0.1 0.2 GO:0016649 electron-transferring-flavoprotein dehydrogenase activity(GO:0004174) oxidoreductase activity, acting on the CH-NH group of donors, quinone or similar compound as acceptor(GO:0016649)
0.1 1.5 GO:0004806 triglyceride lipase activity(GO:0004806)
0.0 0.7 GO:2001069 glycogen binding(GO:2001069)
0.0 0.5 GO:0015386 monovalent cation:proton antiporter activity(GO:0005451) sodium:proton antiporter activity(GO:0015385) potassium:proton antiporter activity(GO:0015386)
0.0 0.1 GO:0047389 glycerophosphocholine phosphodiesterase activity(GO:0047389)
0.0 4.6 GO:0005201 extracellular matrix structural constituent(GO:0005201)
0.0 1.4 GO:0005184 neuropeptide hormone activity(GO:0005184)
0.0 0.2 GO:0004385 guanylate kinase activity(GO:0004385)
0.0 1.2 GO:0017075 syntaxin-1 binding(GO:0017075)
0.0 0.7 GO:0016675 cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors(GO:0016675) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676)
0.0 0.2 GO:0005159 insulin-like growth factor receptor binding(GO:0005159)
0.0 0.5 GO:0005248 voltage-gated sodium channel activity(GO:0005248) voltage-gated ion channel activity involved in regulation of postsynaptic membrane potential(GO:1905030)
0.0 0.6 GO:0004550 nucleoside diphosphate kinase activity(GO:0004550)
0.0 0.5 GO:0005388 calcium-transporting ATPase activity(GO:0005388)
0.0 1.2 GO:0015078 hydrogen ion transmembrane transporter activity(GO:0015078)
0.0 0.1 GO:0015105 arsenite transmembrane transporter activity(GO:0015105)
0.0 0.3 GO:0005452 inorganic anion exchanger activity(GO:0005452)
0.0 0.2 GO:0038191 neuropilin binding(GO:0038191)
0.0 6.3 GO:0005198 structural molecule activity(GO:0005198)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.6 PID INTEGRIN4 PATHWAY Alpha6 beta4 integrin-ligand interactions
0.0 1.0 NABA COLLAGENS Genes encoding collagen proteins
0.0 0.8 PID HDAC CLASSI PATHWAY Signaling events mediated by HDAC Class I
0.0 0.9 NABA ECM AFFILIATED Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 1.6 REACTOME CELL JUNCTION ORGANIZATION Genes involved in Cell junction organization
0.0 1.6 REACTOME RESPIRATORY ELECTRON TRANSPORT Genes involved in Respiratory electron transport
0.0 0.3 REACTOME CREATION OF C4 AND C2 ACTIVATORS Genes involved in Creation of C4 and C2 activators
0.0 0.5 REACTOME GLUCONEOGENESIS Genes involved in Gluconeogenesis
0.0 1.0 REACTOME COLLAGEN FORMATION Genes involved in Collagen formation
0.0 0.8 REACTOME NOTCH1 INTRACELLULAR DOMAIN REGULATES TRANSCRIPTION Genes involved in NOTCH1 Intracellular Domain Regulates Transcription
0.0 2.1 REACTOME ASPARAGINE N LINKED GLYCOSYLATION Genes involved in Asparagine N-linked glycosylation
0.0 0.3 REACTOME CITRIC ACID CYCLE TCA CYCLE Genes involved in Citric acid cycle (TCA cycle)
0.0 0.3 REACTOME LIGAND GATED ION CHANNEL TRANSPORT Genes involved in Ligand-gated ion channel transport
0.0 0.2 REACTOME PROTEOLYTIC CLEAVAGE OF SNARE COMPLEX PROTEINS Genes involved in Proteolytic cleavage of SNARE complex proteins
0.0 0.2 REACTOME GROWTH HORMONE RECEPTOR SIGNALING Genes involved in Growth hormone receptor signaling
0.0 0.1 REACTOME ENDOGENOUS STEROLS Genes involved in Endogenous sterols