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PRJNA195909:zebrafish embryo and larva development

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Results for nr3c1_ar

Z-value: 1.41

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Transcription factors associated with nr3c1_ar

Gene Symbol Gene ID Gene Info
ENSDARG00000025032 nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor)
ENSDARG00000112480 nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor)
ENSDARG00000116957 nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor)
ENSDARG00000067976 androgen receptor
ENSDARG00000114287 androgen receptor

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
ardr11_v1_chr5_+_35561607_35561607-0.353.6e-01Click!
nr3c1dr11_v1_chr14_-_23799345_23799349-0.255.2e-01Click!

Activity profile of nr3c1_ar motif

Sorted Z-values of nr3c1_ar motif

Promoter Log-likelihood Transcript Gene Gene Info
chr6_+_41096058 2.99 ENSDART00000028373
FK506 binding protein 5
chr6_+_41099787 2.32 ENSDART00000186884
FK506 binding protein 5
chr12_+_13256415 2.11 ENSDART00000144542
ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 1, like
chr19_+_10855158 2.07 ENSDART00000172219
ENSDART00000170826
apolipoprotein Ea
chr15_-_9031996 1.77 ENSDART00000124998
reticulon 2a
chr16_+_50089417 1.77 ENSDART00000153675
nuclear receptor subfamily 1, group D, member 2a
chr22_-_968484 1.74 ENSDART00000105895
calcium channel, voltage-dependent, L type, alpha 1S subunit, a
chr16_+_10776688 1.67 ENSDART00000161969
ENSDART00000172657
ATPase Na+/K+ transporting subunit alpha 3b
chr16_-_45225520 1.55 ENSDART00000158855
FXYD domain containing ion transport regulator 1 (phospholemman)
chr16_+_10777116 1.52 ENSDART00000190902
ATPase Na+/K+ transporting subunit alpha 3b
chr8_+_7359294 1.52 ENSDART00000121708
proprotein convertase subtilisin/kexin type 1 inhibitor, like
chr2_-_48196092 1.50 ENSDART00000139944
secondary ossification center associated regulator of chondrocyte maturation
chr14_-_46228094 1.50 ENSDART00000172788
si:ch211-113d11.5
chr7_+_48288762 1.49 ENSDART00000083569
ornithine decarboxylase antizyme 2b
chr12_-_4683325 1.44 ENSDART00000152771
si:ch211-255p10.3
chr7_+_18364176 1.43 ENSDART00000171606
ENSDART00000186368
CD248 molecule, endosialin a
chr7_+_58699718 1.42 ENSDART00000049264
short chain dehydrogenase/reductase family 16C, member 5b
chr7_-_32833153 1.41 ENSDART00000099871
ENSDART00000099872
solute carrier family 17 (vesicular glutamate transporter), member 6b
chr18_-_48745517 1.28 ENSDART00000097259
ST3 beta-galactoside alpha-2,3-sialyltransferase 4
chr20_-_6812688 1.27 ENSDART00000170934
insulin-like growth factor binding protein 1a
chr7_+_6969909 1.26 ENSDART00000189886
actinin alpha 3b
chr20_+_25340814 1.24 ENSDART00000063028
connective tissue growth factor a
chr4_-_20043484 1.19 ENSDART00000167780
zgc:193726
chr10_-_17988779 1.19 ENSDART00000132206
ENSDART00000144841
si:dkey-242g16.2
chr17_-_6730247 1.17 ENSDART00000031091
visinin-like 1b
chr18_+_16744307 1.15 ENSDART00000179872
ENSDART00000133490
lymphatic vessel endothelial hyaluronic receptor 1b
chr4_-_15420452 1.12 ENSDART00000016230
plexin A4
chr1_-_59176949 1.08 ENSDART00000128742

chr17_+_33767890 1.04 ENSDART00000193177
fucosyltransferase 8a (alpha (1,6) fucosyltransferase)
chr21_+_11503212 1.01 ENSDART00000146701
si:dkey-184p9.7
chr15_-_23647078 1.01 ENSDART00000059366
creatine kinase, muscle b
chr15_-_23342752 1.00 ENSDART00000020425
melanoma cell adhesion molecule b
chr9_-_22076368 0.99 ENSDART00000128486
crystallin, gamma M2a
chr25_+_3358701 0.96 ENSDART00000104877
coiled-coil-helix-coiled-coil-helix domain containing 3b
chr1_+_24076243 0.96 ENSDART00000014608
mab-21-like 2
chr5_+_32206378 0.94 ENSDART00000126873
ENSDART00000051361
myosin, heavy polypeptide 2, fast muscle specific
chr23_+_37458602 0.93 ENSDART00000181686
cytidine deaminase a
chr13_+_39236141 0.92 ENSDART00000111458
zgc:172136
chr14_-_28001986 0.91 ENSDART00000054115
TSC22 domain family, member 3
chr20_+_37844035 0.87 ENSDART00000041397
feline leukemia virus subgroup C cellular receptor 1
chr10_-_24343507 0.86 ENSDART00000002974
phosphatidylinositol transfer protein, alpha b
chr21_-_26114886 0.84 ENSDART00000139320
NIPA-like domain containing 4
chr23_+_44732863 0.82 ENSDART00000160044
ENSDART00000172268
ATPase Na+/K+ transporting subunit beta 2a
chr10_+_26667475 0.80 ENSDART00000133281
ENSDART00000147013
si:ch73-52f15.5
chr13_+_912123 0.78 ENSDART00000169931
proprotein convertase subtilisin/kexin type 2
chr18_-_24996634 0.78 ENSDART00000170210
si:ch211-196l7.4
chr5_-_41494831 0.77 ENSDART00000051081
eukaryotic translation elongation factor 2, like 2
chr16_+_32559821 0.77 ENSDART00000093250
POU class 3 homeobox 2b
chr19_+_19412692 0.77 ENSDART00000113580
wu:fc38h03
chr4_+_4232562 0.76 ENSDART00000177529
small lysine rich protein 1
chr20_+_39283849 0.75 ENSDART00000002481
ENSDART00000146683
scavenger receptor class A, member 3
chr24_+_35564668 0.75 ENSDART00000122734
CCAAT/enhancer binding protein (C/EBP), delta
chr3_-_32337653 0.75 ENSDART00000156918
ENSDART00000156551
si:dkey-16p21.8
chr15_-_12011390 0.73 ENSDART00000187403
si:dkey-202l22.6
chr4_-_20156085 0.72 ENSDART00000055317
leucine rich repeat containing 17
chr3_-_35602233 0.71 ENSDART00000055269
guanine nucleotide binding protein (G protein), gamma 13b
chr10_-_36808348 0.71 ENSDART00000099320
dehydrogenase/reductase (SDR family) member 13a, tandem duplicate 1
chr20_+_34915945 0.71 ENSDART00000153064
synaptosomal-associated protein, 25a
chr23_+_35708730 0.70 ENSDART00000009277
tubulin, alpha 1a
chr4_-_11737939 0.70 ENSDART00000150299
podocalyxin-like
chr21_-_25565392 0.68 ENSDART00000144917
ENSDART00000180102
si:dkey-17e16.10
chr21_-_30648106 0.67 ENSDART00000160800
ENSDART00000177022
phosphorylase kinase, alpha 1b (muscle)
chr16_-_50175069 0.66 ENSDART00000192979
lens intrinsic membrane protein 2.5
chr14_-_2355833 0.66 ENSDART00000157677
si:ch73-233f7.6
chr14_+_22114918 0.65 ENSDART00000166610
thioredoxin-related transmembrane protein 2a
chr5_+_9382301 0.65 ENSDART00000124017
UDP glucuronosyltransferase 2 family, polypeptide A7
chr6_-_46875310 0.65 ENSDART00000154442
immunoglobulin-like and fibronectin type III domain containing 1, tandem duplicate 3
chr8_+_35172594 0.64 ENSDART00000177146

chr2_-_155270 0.63 ENSDART00000131177
adenylate cyclase 1b
chr17_+_6276559 0.62 ENSDART00000131075
dual specificity phosphatase 23b
chr5_+_51594209 0.62 ENSDART00000164668
ENSDART00000058403
ENSDART00000055857
creatine kinase, mitochondrial 2b (sarcomeric)
chr4_-_16354292 0.61 ENSDART00000139919
lumican
chr8_-_39984593 0.61 ENSDART00000140127
aspartate beta-hydroxylase domain containing 2
chr4_+_15968483 0.60 ENSDART00000101575
si:dkey-117n7.5
chr20_+_33904258 0.59 ENSDART00000170930
retinoid X receptor, gamma b
chr21_+_30563115 0.59 ENSDART00000028566
si:ch211-200p22.4
chr21_-_41873584 0.58 ENSDART00000188089
endonuclease, polyU-specific 2
chr19_-_47452874 0.58 ENSDART00000025931
transcription factor AP-2 epsilon
chr12_-_43685802 0.58 ENSDART00000170723
zgc:112964
chr4_+_19534833 0.57 ENSDART00000140028
leucine rich repeat containing 4.1
chr18_+_17428506 0.57 ENSDART00000100223
zgc:91860
chr18_+_8346920 0.56 ENSDART00000083421
carnitine palmitoyltransferase 1B (muscle)
chr19_+_30633453 0.55 ENSDART00000052124
family with sequence similarity 49, member A-like
chr5_-_43935460 0.54 ENSDART00000166152
ENSDART00000188969
si:ch211-204c21.1
chr8_+_19674369 0.54 ENSDART00000138176
forkhead box D2
chr1_-_39909985 0.53 ENSDART00000181673
storkhead box 2a
chr6_+_9130989 0.53 ENSDART00000162588
regucalcin
chr18_-_44611252 0.53 ENSDART00000173095
sprouty-related, EVH1 domain containing 3
chr10_+_21758811 0.53 ENSDART00000188827
protocadherin 1 gamma 11
chr11_-_236984 0.53 ENSDART00000170778
dual specificity phosphatase 7
chr12_-_46959990 0.52 ENSDART00000084557
phospholysine phosphohistidine inorganic pyrophosphate phosphatase
chr25_-_3470910 0.52 ENSDART00000029067
ENSDART00000186737
HMG-box transcription factor 1
chr18_+_17428258 0.52 ENSDART00000010452
zgc:91860
chr9_-_21918963 0.52 ENSDART00000090782
LIM domain 7a
chr4_+_4803698 0.51 ENSDART00000129252
solute carrier family 13 (sodium/sulfate symporter), member 4
chr10_+_34315719 0.51 ENSDART00000135303
StAR-related lipid transfer (START) domain containing 13a
chr17_+_52822422 0.51 ENSDART00000158273
ENSDART00000161414
Meis homeobox 2a
chr21_+_28478663 0.51 ENSDART00000077887
ENSDART00000134150
solute carrier family 22 (organic anion transporter), member 6, like
chr16_+_46430627 0.51 ENSDART00000127681
rapunzel 6
chr24_+_7637522 0.50 ENSDART00000082467
caveolae associated protein 1b
chr24_+_23742690 0.50 ENSDART00000130162
transcription factor 24
chr6_-_40583253 0.49 ENSDART00000032603
translocator protein
chr11_-_236766 0.49 ENSDART00000163978
dual specificity phosphatase 7
chr20_-_29475172 0.49 ENSDART00000183164
secretogranin V
chr6_-_6448519 0.48 ENSDART00000180157
ENSDART00000191112
si:ch211-194e18.2
chr19_+_7717449 0.48 ENSDART00000104719
ENSDART00000146747
tuftelin 1b
chr24_-_9960290 0.48 ENSDART00000143390
ENSDART00000092975
ENSDART00000184953
vacuolar protein sorting 41 homolog (S. cerevisiae)
chr22_-_13350240 0.48 ENSDART00000154095
ENSDART00000155118
si:ch211-227m13.1
chr3_-_60571218 0.48 ENSDART00000178981
si:ch73-366l1.5
chr25_-_3469576 0.47 ENSDART00000186738
HMG-box transcription factor 1
chr5_+_23256187 0.47 ENSDART00000168717
ENSDART00000142915
si:dkey-125i10.3
chr4_+_25651720 0.47 ENSDART00000100693
ENSDART00000100717
acyl-CoA thioesterase 16
chr12_+_16440708 0.47 ENSDART00000113810
ankyrin repeat domain 1b (cardiac muscle)
chr20_-_34801181 0.46 ENSDART00000048375
ENSDART00000132426
stathmin-like 4
chr2_+_13056802 0.46 ENSDART00000142649
protein kinase, AMP-activated, gamma 2 non-catalytic subunit b
chr23_+_4890693 0.46 ENSDART00000023537
troponin C type 1a (slow)
chr3_-_58543658 0.45 ENSDART00000042386
un-named sa1261
chr5_-_43935119 0.45 ENSDART00000142271
si:ch211-204c21.1
chr11_-_25829712 0.45 ENSDART00000103549
v-ski avian sarcoma viral oncogene homolog b
chr8_+_1065458 0.44 ENSDART00000081432
sepiapterin reductase b
chr20_+_34543365 0.44 ENSDART00000152073
si:ch211-242b18.1
chr1_-_26782573 0.44 ENSDART00000090611
SH3 domain containing GRB2 like 2a, endophilin A1
chr19_-_32487469 0.44 ENSDART00000050130
guanosine monophosphate reductase
chr5_-_24238733 0.44 ENSDART00000138170
phospholipid scramblase 3a
chr20_+_46586678 0.43 ENSDART00000014166
ENSDART00000179266
Jun dimerization protein 2b
chr13_+_25846528 0.43 ENSDART00000087426
B cell CLL/lymphoma 11Aa
chr5_-_31901468 0.42 ENSDART00000147814
ENSDART00000141446
coronin, actin binding protein, 1Cb
chr13_-_45523026 0.42 ENSDART00000020663
Rh blood group, D antigen
chr5_+_9360394 0.42 ENSDART00000124642

chr23_+_9088191 0.41 ENSDART00000030811
Cdk5 and Abl enzyme substrate 2b
chr17_-_37395460 0.40 ENSDART00000148160
ENSDART00000075975
cysteine-rich protein 1
chr18_+_29156827 0.40 ENSDART00000137587
ENSDART00000135633
PTPRF interacting protein, binding protein 2a (liprin beta 2)
chr2_-_65529 0.40 ENSDART00000192876
zgc:153913
chr25_+_5044780 0.40 ENSDART00000153980
parvin, beta
chr10_+_29431529 0.40 ENSDART00000158154
discs, large homolog 2 (Drosophila)
chr14_-_2270973 0.39 ENSDART00000180729
protocadherin 2 alpha b 9
chr7_-_8577190 0.39 ENSDART00000173174
jacalin 3
chr7_-_18168493 0.39 ENSDART00000127428
pellino E3 ubiquitin protein ligase family member 3
chr14_-_36863432 0.39 ENSDART00000158052
ring finger protein 130
chr8_+_8459192 0.38 ENSDART00000140942
ENSDART00000014939
catechol-O-methyltransferase a
chr13_+_29510023 0.38 ENSDART00000187398
carbohydrate (chondroitin 6) sulfotransferase 3a
chr5_-_37252111 0.38 ENSDART00000185110
leucine-rich repeats and calponin homology (CH) domain containing 2
chr21_+_32338897 0.38 ENSDART00000110137
si:ch211-247j9.1
chr15_-_12011202 0.37 ENSDART00000160427
ENSDART00000168715
si:dkey-202l22.6
chr2_-_22688651 0.36 ENSDART00000013863
alanine-glyoxylate aminotransferase b
chr17_+_29345606 0.36 ENSDART00000086164
potassium channel tetramerization domain containing 3
chr23_+_6752828 0.36 ENSDART00000105179
zgc:158254
chr23_-_39849155 0.36 ENSDART00000115330
protein phosphatase 1, regulatory (inhibitor) subunit 14C
chr1_-_55008882 0.36 ENSDART00000083572
zgc:136864
chr5_-_23362602 0.36 ENSDART00000137120
glutamate receptor, ionotropic, AMPA 3a
chr21_-_19316985 0.35 ENSDART00000141596
glycerol-3-phosphate acyltransferase 3
chr25_-_24046870 0.35 ENSDART00000047569
insulin-like growth factor 2b
chr4_-_2014406 0.35 ENSDART00000180463
si:dkey-97m3.1
chr18_+_50278858 0.34 ENSDART00000014582
si:dkey-105e17.1
chr4_-_12725513 0.34 ENSDART00000132286
microsomal glutathione S-transferase 1.2
chr1_-_45049603 0.34 ENSDART00000023336
ribosomal protein S6
chr10_-_43294933 0.34 ENSDART00000062631
hyaluronan and proteoglycan link protein 1b
chr6_-_27123327 0.34 ENSDART00000073881
alanine-glyoxylate aminotransferase a
chr4_+_76735113 0.34 ENSDART00000075602
membrane-spanning 4-domains, subfamily A, member 17A.6
chr15_+_37559570 0.33 ENSDART00000085522
heat shock protein, alpha-crystallin-related, b6
chr15_-_24883956 0.33 ENSDART00000113199
aryl hydrocarbon receptor interacting protein-like 1
chr3_+_62205858 0.33 ENSDART00000126807
zgc:173575
chr11_+_13630107 0.33 ENSDART00000172220
si:ch211-1a19.3
chr15_-_31000275 0.33 ENSDART00000132493
ENSDART00000100183
lectin, galactoside-binding, soluble, 9 (galectin 9)-like 6
lectin, galactoside-binding, soluble, 9 (galectin 9)-like 5
chr24_+_7637264 0.32 ENSDART00000124409
caveolae associated protein 1b
chr15_-_31372486 0.32 ENSDART00000127447
odorant receptor, family D, subfamily 111, member 4
chr21_-_131236 0.32 ENSDART00000160005
si:ch1073-398f15.1
chr15_-_29388012 0.32 ENSDART00000115032
serpin peptidase inhibitor, clade H (heat shock protein 47), member 1b
chr4_-_11163112 0.31 ENSDART00000188854
protein arginine methyltransferase 8b
chr21_-_32289356 0.31 ENSDART00000183050
CDC-like kinase 4b
chr21_+_1378250 0.31 ENSDART00000186912
transcription factor 4
chr8_-_46700278 0.30 ENSDART00000143780
G protein-coupled receptor 153
chr23_+_17865953 0.30 ENSDART00000014723
ENSDART00000140302
ENSDART00000144800
nascent polypeptide-associated complex alpha subunit
chr15_+_7064819 0.30 ENSDART00000155268
phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit beta
chr19_+_22216778 0.30 ENSDART00000052521
nuclear factor of activated T cells 1
chr22_+_10010292 0.29 ENSDART00000180096

chr6_-_13114821 0.29 ENSDART00000164579
ENSDART00000165375
zgc:194469
chr6_-_27057702 0.29 ENSDART00000149363
serine/threonine kinase 25a
chr6_-_15096556 0.29 ENSDART00000185327
four and a half LIM domains 2b
chr15_-_5742531 0.29 ENSDART00000045985
phosphorylase kinase, gamma 1a (muscle)
chr10_+_41199660 0.29 ENSDART00000125314
adrenoceptor beta 3b
chr16_-_46619967 0.29 ENSDART00000158341
transmembrane protein 176l.3a
chr11_+_6152643 0.29 ENSDART00000012789
solute carrier family 1 (high affinity aspartate/glutamate transporter), member 6
chr14_+_52571134 0.29 ENSDART00000166708
ribosomal protein L26
chr5_-_37900350 0.28 ENSDART00000084839
ENSDART00000084841
ENSDART00000133437
transmembrane protease, serine 13b
chr11_-_25829006 0.28 ENSDART00000159214
v-ski avian sarcoma viral oncogene homolog b
chr10_-_24689280 0.28 ENSDART00000191476
si:ch211-287a12.9
chr19_-_41213718 0.28 ENSDART00000077121
pyruvate dehydrogenase kinase, isozyme 4
chr10_+_26669177 0.28 ENSDART00000143402
si:ch73-52f15.5
chr5_+_32162684 0.28 ENSDART00000134472
TAO kinase 3b
chr19_+_43256986 0.28 ENSDART00000182336
diacylglycerol kinase delta
chr1_-_1631399 0.28 ENSDART00000176787
chloride intracellular channel 6
chr3_-_35800221 0.27 ENSDART00000031390
CASK interacting protein 1
chr23_-_5685023 0.27 ENSDART00000148680
ENSDART00000149365
troponin T type 2a (cardiac)
chr20_-_791788 0.27 ENSDART00000134128
interphotoreceptor matrix proteoglycan 1a
chr19_-_205104 0.27 ENSDART00000011890
zinc finger and BTB domain containing 22a
chr7_-_35036770 0.27 ENSDART00000123174
galanin receptor 1b
chr7_-_29340427 0.26 ENSDART00000052584
transient receptor potential cation channel, subfamily M, member 1a
chr5_-_3627110 0.26 ENSDART00000156071
si:zfos-375h5.1
chr8_+_53452681 0.26 ENSDART00000166705
calcium channel, voltage-dependent, L type, alpha 1D subunit, b

Network of associatons between targets according to the STRING database.

First level regulatory network of nr3c1_ar

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 2.1 GO:0051000 regulation of nitric-oxide synthase activity(GO:0050999) positive regulation of nitric-oxide synthase activity(GO:0051000) beta-amyloid clearance(GO:0097242) regulation of beta-amyloid clearance(GO:1900221)
0.4 1.1 GO:0007414 axonal defasciculation(GO:0007414)
0.3 0.9 GO:0009972 cytidine catabolic process(GO:0006216) cytidine deamination(GO:0009972) cytidine metabolic process(GO:0046087)
0.2 0.7 GO:0033632 cell-cell adhesion mediated by integrin(GO:0033631) regulation of cell-cell adhesion mediated by integrin(GO:0033632)
0.2 0.9 GO:0097037 heme export(GO:0097037)
0.2 4.0 GO:0030007 cellular potassium ion homeostasis(GO:0030007) sodium ion export from cell(GO:0036376) sodium ion export(GO:0071436)
0.2 0.5 GO:0019852 L-ascorbic acid metabolic process(GO:0019852) water-soluble vitamin biosynthetic process(GO:0042364)
0.2 1.4 GO:0098700 neurotransmitter loading into synaptic vesicle(GO:0098700)
0.2 5.3 GO:0000413 protein peptidyl-prolyl isomerization(GO:0000413)
0.2 0.9 GO:0035332 positive regulation of hippo signaling(GO:0035332)
0.1 0.4 GO:0097237 cellular response to antibiotic(GO:0071236) cellular response to toxic substance(GO:0097237)
0.1 1.6 GO:0046314 phosphagen metabolic process(GO:0006599) phosphocreatine metabolic process(GO:0006603) phosphagen biosynthetic process(GO:0042396) phosphocreatine biosynthetic process(GO:0046314)
0.1 0.7 GO:0006545 glycine biosynthetic process(GO:0006545)
0.1 1.3 GO:0043567 regulation of insulin-like growth factor receptor signaling pathway(GO:0043567)
0.1 0.4 GO:2000171 negative regulation of dendrite development(GO:2000171)
0.1 2.2 GO:0006825 copper ion transport(GO:0006825)
0.1 1.0 GO:0061303 cornea development in camera-type eye(GO:0061303)
0.1 0.5 GO:0010799 regulation of peptidyl-threonine phosphorylation(GO:0010799) negative regulation of peptidyl-threonine phosphorylation(GO:0010801)
0.1 0.7 GO:0021634 optic nerve formation(GO:0021634)
0.1 1.2 GO:0035970 peptidyl-threonine dephosphorylation(GO:0035970)
0.1 0.4 GO:0008592 regulation of Toll signaling pathway(GO:0008592)
0.1 0.2 GO:1990575 mitochondrial ornithine transport(GO:0000066) mitochondrial L-ornithine transmembrane transport(GO:1990575)
0.1 1.7 GO:0006595 polyamine metabolic process(GO:0006595)
0.1 1.4 GO:0014823 response to activity(GO:0014823)
0.1 0.3 GO:0003228 atrial cardiac muscle tissue development(GO:0003228)
0.1 0.2 GO:0036159 inner dynein arm assembly(GO:0036159)
0.1 0.3 GO:0035739 negative regulation of interferon-gamma production(GO:0032689) CD4-positive, alpha-beta T cell proliferation(GO:0035739) regulation of CD4-positive, alpha-beta T cell proliferation(GO:2000561) negative regulation of CD4-positive, alpha-beta T cell proliferation(GO:2000562)
0.1 0.2 GO:1902626 assembly of large subunit precursor of preribosome(GO:1902626)
0.1 0.7 GO:0050909 sensory perception of taste(GO:0050909)
0.1 1.0 GO:0036065 fucosylation(GO:0036065)
0.1 0.4 GO:0019614 catechol-containing compound catabolic process(GO:0019614) catecholamine catabolic process(GO:0042424)
0.1 0.2 GO:0030091 protein repair(GO:0030091)
0.1 0.5 GO:0034058 endosomal vesicle fusion(GO:0034058)
0.1 0.3 GO:0002025 vasodilation by norepinephrine-epinephrine involved in regulation of systemic arterial blood pressure(GO:0002025)
0.1 0.2 GO:0003376 sphingosine-1-phosphate signaling pathway(GO:0003376) anterior lateral line neuromast hair cell development(GO:0035676)
0.1 0.3 GO:1900028 wound healing, spreading of epidermal cells(GO:0035313) negative regulation of ruffle assembly(GO:1900028)
0.1 0.4 GO:0031063 regulation of histone deacetylation(GO:0031063)
0.1 0.3 GO:0060402 cytosolic calcium ion transport(GO:0060401) calcium ion transport into cytosol(GO:0060402)
0.1 1.2 GO:0005979 regulation of glycogen biosynthetic process(GO:0005979) regulation of glucan biosynthetic process(GO:0010962)
0.1 0.8 GO:0016486 peptide hormone processing(GO:0016486)
0.1 0.2 GO:0021742 abducens nucleus development(GO:0021742)
0.1 0.2 GO:1904983 transmembrane glycine transport from cytosol to mitochondrion(GO:1904983)
0.0 0.8 GO:0015693 magnesium ion transport(GO:0015693)
0.0 1.0 GO:0060287 epithelial cilium movement involved in determination of left/right asymmetry(GO:0060287)
0.0 0.2 GO:0031443 fast-twitch skeletal muscle fiber contraction(GO:0031443)
0.0 0.1 GO:0006957 complement activation, alternative pathway(GO:0006957) regulation of protein activation cascade(GO:2000257)
0.0 0.6 GO:0016199 axon midline choice point recognition(GO:0016199)
0.0 0.4 GO:0046146 tetrahydrobiopterin biosynthetic process(GO:0006729) tetrahydrobiopterin metabolic process(GO:0046146)
0.0 0.3 GO:0046341 CDP-diacylglycerol biosynthetic process(GO:0016024) CDP-diacylglycerol metabolic process(GO:0046341)
0.0 0.7 GO:0042574 retinal metabolic process(GO:0042574)
0.0 1.1 GO:0007007 inner mitochondrial membrane organization(GO:0007007)
0.0 0.3 GO:0072488 ammonium transmembrane transport(GO:0072488)
0.0 0.6 GO:0009437 carnitine metabolic process(GO:0009437)
0.0 0.9 GO:0030513 positive regulation of BMP signaling pathway(GO:0030513)
0.0 0.2 GO:0071340 skeletal muscle acetylcholine-gated channel clustering(GO:0071340)
0.0 1.3 GO:0032922 circadian regulation of gene expression(GO:0032922)
0.0 0.6 GO:0030512 negative regulation of transforming growth factor beta receptor signaling pathway(GO:0030512) negative regulation of cellular response to transforming growth factor beta stimulus(GO:1903845)
0.0 0.2 GO:0070373 negative regulation of ERK1 and ERK2 cascade(GO:0070373)
0.0 0.9 GO:0030199 collagen fibril organization(GO:0030199)
0.0 0.4 GO:0030206 N-acetylglucosamine metabolic process(GO:0006044) chondroitin sulfate biosynthetic process(GO:0030206)
0.0 0.7 GO:0032526 response to retinoic acid(GO:0032526)
0.0 0.1 GO:0045218 zonula adherens maintenance(GO:0045218)
0.0 0.3 GO:0051481 negative regulation of cytosolic calcium ion concentration(GO:0051481) negative regulation of synaptic transmission, glutamatergic(GO:0051967)
0.0 0.1 GO:0055005 ventricular cardiac myofibril assembly(GO:0055005)
0.0 0.4 GO:0006144 purine nucleobase metabolic process(GO:0006144)
0.0 0.3 GO:0033173 calcineurin-NFAT signaling cascade(GO:0033173)
0.0 0.6 GO:0016185 synaptic vesicle budding from presynaptic endocytic zone membrane(GO:0016185)
0.0 0.4 GO:0018401 peptidyl-proline hydroxylation to 4-hydroxy-L-proline(GO:0018401) 4-hydroxyproline metabolic process(GO:0019471)
0.0 0.3 GO:0044154 histone H3-K14 acetylation(GO:0044154)
0.0 0.4 GO:0010923 negative regulation of phosphatase activity(GO:0010923)
0.0 0.3 GO:0018216 peptidyl-arginine methylation(GO:0018216)
0.0 0.1 GO:2001270 negative regulation of execution phase of apoptosis(GO:1900118) regulation of cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:2001270) negative regulation of cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:2001271)
0.0 1.0 GO:0009247 glycolipid biosynthetic process(GO:0009247)
0.0 0.4 GO:0030032 lamellipodium assembly(GO:0030032)
0.0 0.4 GO:0035622 intrahepatic bile duct development(GO:0035622)
0.0 3.9 GO:0070588 calcium ion transmembrane transport(GO:0070588)
0.0 0.4 GO:0070593 dendrite self-avoidance(GO:0070593)
0.0 0.3 GO:0036092 phosphatidylinositol-3-phosphate biosynthetic process(GO:0036092)
0.0 0.2 GO:0006607 NLS-bearing protein import into nucleus(GO:0006607)
0.0 0.1 GO:0060573 ventral spinal cord interneuron specification(GO:0021521) cell fate specification involved in pattern specification(GO:0060573) embryonic skeletal joint development(GO:0072498)
0.0 0.4 GO:0016082 synaptic vesicle priming(GO:0016082)
0.0 0.1 GO:0046959 nonassociative learning(GO:0046958) habituation(GO:0046959)
0.0 0.3 GO:0042102 positive regulation of T cell proliferation(GO:0042102)
0.0 0.5 GO:0060319 primitive erythrocyte differentiation(GO:0060319)
0.0 0.1 GO:0045448 regulation of mitotic cell cycle, embryonic(GO:0009794) mitotic cell cycle, embryonic(GO:0045448)
0.0 0.4 GO:0017121 phospholipid scrambling(GO:0017121)
0.0 0.0 GO:0036076 ligamentous ossification(GO:0036076)
0.0 0.5 GO:0042149 cellular response to glucose starvation(GO:0042149)
0.0 0.8 GO:0006414 translational elongation(GO:0006414)
0.0 0.7 GO:0050919 negative chemotaxis(GO:0050919)
0.0 0.1 GO:1990118 sodium ion import(GO:0097369) inorganic cation import into cell(GO:0098659) sodium ion import across plasma membrane(GO:0098719) inorganic ion import into cell(GO:0099587) sodium ion import into cell(GO:1990118)
0.0 0.3 GO:0010906 regulation of glucose metabolic process(GO:0010906)
0.0 0.2 GO:0006120 mitochondrial electron transport, NADH to ubiquinone(GO:0006120)
0.0 0.1 GO:0006361 transcription initiation from RNA polymerase I promoter(GO:0006361)
0.0 0.1 GO:0030859 polarized epithelial cell differentiation(GO:0030859)
0.0 0.1 GO:0050957 neuromuscular process controlling balance(GO:0050885) equilibrioception(GO:0050957)
0.0 0.5 GO:1902749 regulation of cell cycle G2/M phase transition(GO:1902749)
0.0 0.1 GO:0035094 response to nicotine(GO:0035094)
0.0 0.1 GO:0060005 reflex(GO:0060004) vestibular reflex(GO:0060005)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 2.1 GO:0034363 intermediate-density lipoprotein particle(GO:0034363)
0.1 0.4 GO:1902560 GMP reductase complex(GO:1902560)
0.1 0.7 GO:0070032 synaptobrevin 2-SNAP-25-syntaxin-1a-complexin I complex(GO:0070032)
0.1 0.3 GO:0098753 intrinsic component of the cytoplasmic side of the plasma membrane(GO:0031235) anchored component of the cytoplasmic side of the plasma membrane(GO:0098753)
0.1 1.1 GO:0061617 MICOS complex(GO:0061617)
0.1 0.5 GO:0030897 HOPS complex(GO:0030897)
0.1 1.4 GO:0098563 integral component of synaptic vesicle membrane(GO:0030285) intrinsic component of synaptic vesicle membrane(GO:0098563)
0.1 2.3 GO:0033017 sarcoplasmic reticulum membrane(GO:0033017)
0.1 0.8 GO:0005890 sodium:potassium-exchanging ATPase complex(GO:0005890) cation-transporting ATPase complex(GO:0090533)
0.1 1.2 GO:0000164 protein phosphatase type 1 complex(GO:0000164)
0.1 0.7 GO:0031528 microvillus membrane(GO:0031528)
0.1 0.8 GO:0005964 phosphorylase kinase complex(GO:0005964)
0.1 1.1 GO:0002116 semaphorin receptor complex(GO:0002116)
0.1 0.6 GO:0098894 presynaptic endocytic zone(GO:0098833) presynaptic endocytic zone membrane(GO:0098835) extrinsic component of presynaptic membrane(GO:0098888) extrinsic component of presynaptic endocytic zone(GO:0098894)
0.1 0.3 GO:0005854 nascent polypeptide-associated complex(GO:0005854)
0.0 2.1 GO:0031970 mitochondrial intermembrane space(GO:0005758) organelle envelope lumen(GO:0031970)
0.0 0.5 GO:0031588 nucleotide-activated protein kinase complex(GO:0031588)
0.0 0.3 GO:0033165 interphotoreceptor matrix(GO:0033165)
0.0 1.5 GO:0005811 lipid particle(GO:0005811)
0.0 2.0 GO:0005891 voltage-gated calcium channel complex(GO:0005891)
0.0 0.1 GO:0033263 CORVET complex(GO:0033263)
0.0 0.9 GO:0044853 caveola(GO:0005901) plasma membrane raft(GO:0044853)
0.0 0.1 GO:0043291 RAVE complex(GO:0043291)
0.0 1.0 GO:0032580 Golgi cisterna membrane(GO:0032580)
0.0 0.7 GO:0005861 troponin complex(GO:0005861)
0.0 0.2 GO:0002102 podosome(GO:0002102)
0.0 0.3 GO:0070775 H3 histone acetyltransferase complex(GO:0070775) MOZ/MORF histone acetyltransferase complex(GO:0070776)
0.0 0.1 GO:0031931 TORC1 complex(GO:0031931)
0.0 0.1 GO:0031526 brush border membrane(GO:0031526)
0.0 0.2 GO:0032588 trans-Golgi network membrane(GO:0032588)
0.0 0.7 GO:0005834 heterotrimeric G-protein complex(GO:0005834)
0.0 0.1 GO:0005915 cell-cell adherens junction(GO:0005913) zonula adherens(GO:0005915)
0.0 0.1 GO:0045252 oxoglutarate dehydrogenase complex(GO:0045252)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
1.3 5.3 GO:0005527 macrolide binding(GO:0005527) FK506 binding(GO:0005528)
0.5 1.4 GO:1990430 extracellular matrix protein binding(GO:1990430)
0.4 2.2 GO:0016531 copper chaperone activity(GO:0016531)
0.4 1.5 GO:0008073 ornithine decarboxylase inhibitor activity(GO:0008073)
0.3 3.2 GO:0005391 sodium:potassium-exchanging ATPase activity(GO:0005391)
0.2 0.8 GO:0042134 rRNA primary transcript binding(GO:0042134)
0.1 0.4 GO:0016657 GMP reductase activity(GO:0003920) oxidoreductase activity, acting on NAD(P)H, nitrogenous group as acceptor(GO:0016657)
0.1 0.9 GO:0004126 cytidine deaminase activity(GO:0004126)
0.1 0.5 GO:0004427 inorganic diphosphatase activity(GO:0004427) protein histidine phosphatase activity(GO:0101006)
0.1 0.4 GO:0016206 catechol O-methyltransferase activity(GO:0016206)
0.1 1.6 GO:0016775 creatine kinase activity(GO:0004111) phosphotransferase activity, nitrogenous group as acceptor(GO:0016775)
0.1 2.1 GO:0008553 hydrogen-exporting ATPase activity, phosphorylative mechanism(GO:0008553)
0.1 0.9 GO:0008526 phosphatidylinositol transporter activity(GO:0008526)
0.1 0.5 GO:0061629 RNA polymerase II sequence-specific DNA binding transcription factor binding(GO:0061629)
0.1 1.3 GO:0031994 insulin-like growth factor I binding(GO:0031994) insulin-like growth factor II binding(GO:0031995)
0.1 0.9 GO:0015232 heme transporter activity(GO:0015232)
0.1 1.4 GO:0005326 neurotransmitter transporter activity(GO:0005326)
0.1 0.4 GO:0008459 chondroitin 6-sulfotransferase activity(GO:0008459)
0.1 1.2 GO:0008330 protein tyrosine/threonine phosphatase activity(GO:0008330)
0.1 0.6 GO:0016416 carnitine O-palmitoyltransferase activity(GO:0004095) O-palmitoyltransferase activity(GO:0016416)
0.1 1.2 GO:2001069 glycogen binding(GO:2001069)
0.1 0.3 GO:0051380 norepinephrine binding(GO:0051380)
0.1 0.7 GO:0052650 NADP-retinol dehydrogenase activity(GO:0052650)
0.1 2.0 GO:0008331 high voltage-gated calcium channel activity(GO:0008331)
0.1 0.6 GO:0044323 retinoic acid-responsive element binding(GO:0044323)
0.1 1.0 GO:0008417 fucosyltransferase activity(GO:0008417)
0.1 0.2 GO:0102345 3-hydroxyacyl-CoA dehydratase activity(GO:0018812) 3-hydroxy-behenoyl-CoA dehydratase activity(GO:0102344) 3-hydroxy-lignoceroyl-CoA dehydratase activity(GO:0102345)
0.1 0.9 GO:0033613 activating transcription factor binding(GO:0033613)
0.0 0.3 GO:0080019 fatty-acyl-CoA reductase (alcohol-forming) activity(GO:0080019)
0.0 0.2 GO:0005219 ryanodine-sensitive calcium-release channel activity(GO:0005219) calcium-induced calcium release activity(GO:0048763)
0.0 0.6 GO:0005545 1-phosphatidylinositol binding(GO:0005545)
0.0 0.7 GO:0048495 Roundabout binding(GO:0048495)
0.0 0.3 GO:0004966 galanin receptor activity(GO:0004966)
0.0 0.3 GO:0035242 protein-arginine omega-N asymmetric methyltransferase activity(GO:0035242)
0.0 0.3 GO:0004366 glycerol-3-phosphate O-acyltransferase activity(GO:0004366)
0.0 0.3 GO:0005159 insulin-like growth factor receptor binding(GO:0005159)
0.0 0.8 GO:0001671 ATPase activator activity(GO:0001671)
0.0 0.2 GO:0033743 peptide-methionine (R)-S-oxide reductase activity(GO:0033743)
0.0 0.4 GO:0004865 protein serine/threonine phosphatase inhibitor activity(GO:0004865)
0.0 1.5 GO:0005540 hyaluronic acid binding(GO:0005540)
0.0 0.3 GO:0019809 spermidine binding(GO:0019809)
0.0 0.4 GO:0017128 phospholipid scramblase activity(GO:0017128)
0.0 1.1 GO:0017154 semaphorin receptor activity(GO:0017154)
0.0 0.3 GO:0004740 pyruvate dehydrogenase (acetyl-transferring) kinase activity(GO:0004740)
0.0 0.7 GO:0031681 G-protein beta-subunit binding(GO:0031681)
0.0 0.3 GO:0016936 galactoside binding(GO:0016936)
0.0 0.2 GO:0004977 melanocortin receptor activity(GO:0004977)
0.0 0.3 GO:0004563 beta-N-acetylhexosaminidase activity(GO:0004563)
0.0 0.4 GO:0004656 procollagen-proline 4-dioxygenase activity(GO:0004656)
0.0 0.8 GO:0008483 transaminase activity(GO:0008483)
0.0 0.3 GO:0046934 phosphatidylinositol-4,5-bisphosphate 3-kinase activity(GO:0046934) phosphatidylinositol-3,4-bisphosphate 5-kinase activity(GO:0052812)
0.0 0.2 GO:0032422 purine-rich negative regulatory element binding(GO:0032422)
0.0 0.2 GO:0038062 protein tyrosine kinase collagen receptor activity(GO:0038062) collagen receptor activity(GO:0038064)
0.0 0.2 GO:0000064 L-ornithine transmembrane transporter activity(GO:0000064)
0.0 0.6 GO:0047617 acyl-CoA hydrolase activity(GO:0047617)
0.0 0.3 GO:0031013 troponin C binding(GO:0030172) troponin I binding(GO:0031013)
0.0 0.4 GO:0004971 AMPA glutamate receptor activity(GO:0004971)
0.0 0.3 GO:0031628 opioid receptor binding(GO:0031628)
0.0 0.0 GO:0050220 prostaglandin-E synthase activity(GO:0050220)
0.0 0.1 GO:0070097 delta-catenin binding(GO:0070097)
0.0 0.2 GO:0038036 sphingosine-1-phosphate receptor activity(GO:0038036)
0.0 0.3 GO:0001591 dopamine neurotransmitter receptor activity, coupled via Gi/Go(GO:0001591)
0.0 0.1 GO:0004689 phosphorylase kinase activity(GO:0004689)
0.0 0.1 GO:0043295 glutathione binding(GO:0043295)
0.0 1.6 GO:0005212 structural constituent of eye lens(GO:0005212)
0.0 0.4 GO:0015095 magnesium ion transmembrane transporter activity(GO:0015095)
0.0 0.2 GO:0004687 myosin light chain kinase activity(GO:0004687)
0.0 0.3 GO:0043994 H3 histone acetyltransferase activity(GO:0010484) histone acetyltransferase activity (H3-K23 specific)(GO:0043994)
0.0 0.1 GO:0003839 gamma-glutamylcyclotransferase activity(GO:0003839)
0.0 0.4 GO:0004364 glutathione transferase activity(GO:0004364)
0.0 0.8 GO:0003746 translation elongation factor activity(GO:0003746)
0.0 0.7 GO:0015036 disulfide oxidoreductase activity(GO:0015036)
0.0 0.5 GO:0016208 AMP binding(GO:0016208)
0.0 0.7 GO:0017075 syntaxin-1 binding(GO:0017075)
0.0 0.5 GO:0048306 calcium-dependent protein binding(GO:0048306)
0.0 1.6 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
0.0 0.1 GO:0004591 oxoglutarate dehydrogenase (succinyl-transferring) activity(GO:0004591)
0.0 1.1 GO:0008201 heparin binding(GO:0008201)
0.0 0.3 GO:0008519 ammonium transmembrane transporter activity(GO:0008519)
0.0 0.1 GO:0016918 retinal binding(GO:0016918)
0.0 0.1 GO:0004999 vasoactive intestinal polypeptide receptor activity(GO:0004999)
0.0 1.5 GO:0004879 RNA polymerase II transcription factor activity, ligand-activated sequence-specific DNA binding(GO:0004879)
0.0 0.4 GO:0098632 protein binding involved in cell-cell adhesion(GO:0098632)
0.0 0.7 GO:0046332 SMAD binding(GO:0046332)
0.0 0.2 GO:0061608 nuclear import signal receptor activity(GO:0061608)
0.0 0.2 GO:0015187 glycine transmembrane transporter activity(GO:0015187)
0.0 1.5 GO:0016616 oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor(GO:0016616)
0.0 0.1 GO:0005451 monovalent cation:proton antiporter activity(GO:0005451) sodium:proton antiporter activity(GO:0015385) potassium:proton antiporter activity(GO:0015386)
0.0 0.0 GO:0000810 diacylglycerol diphosphate phosphatase activity(GO:0000810)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 5.3 PID REG GR PATHWAY Glucocorticoid receptor regulatory network
0.0 1.6 PID DELTA NP63 PATHWAY Validated transcriptional targets of deltaNp63 isoforms
0.0 0.2 PID PI3KCI AKT PATHWAY Class I PI3K signaling events mediated by Akt
0.0 0.6 NABA PROTEOGLYCANS Genes encoding proteoglycans
0.0 1.1 NABA ECM AFFILIATED Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.0 0.2 PID S1P S1P3 PATHWAY S1P3 pathway
0.0 0.6 PID HNF3B PATHWAY FOXA2 and FOXA3 transcription factor networks
0.0 0.8 PID P73PATHWAY p73 transcription factor network
0.0 0.3 PID IL2 PI3K PATHWAY IL2 signaling events mediated by PI3K
0.0 0.3 PID INTEGRIN A4B1 PATHWAY Alpha4 beta1 integrin signaling events
0.0 0.2 PID RAS PATHWAY Regulation of Ras family activation
0.0 0.4 PID ILK PATHWAY Integrin-linked kinase signaling
0.0 0.2 PID NEPHRIN NEPH1 PATHWAY Nephrin/Neph1 signaling in the kidney podocyte

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.2 REACTOME ERKS ARE INACTIVATED Genes involved in ERKs are inactivated
0.1 0.6 REACTOME KERATAN SULFATE DEGRADATION Genes involved in Keratan sulfate degradation
0.0 0.9 REACTOME IRON UPTAKE AND TRANSPORT Genes involved in Iron uptake and transport
0.0 0.4 REACTOME MTORC1 MEDIATED SIGNALLING Genes involved in mTORC1-mediated signalling
0.0 0.4 REACTOME PURINE SALVAGE Genes involved in Purine salvage
0.0 0.7 REACTOME POST CHAPERONIN TUBULIN FOLDING PATHWAY Genes involved in Post-chaperonin tubulin folding pathway
0.0 0.8 REACTOME INSULIN SYNTHESIS AND PROCESSING Genes involved in Insulin Synthesis and Processing
0.0 0.3 REACTOME GLUTAMATE NEUROTRANSMITTER RELEASE CYCLE Genes involved in Glutamate Neurotransmitter Release Cycle
0.0 0.6 REACTOME ACTIVATED AMPK STIMULATES FATTY ACID OXIDATION IN MUSCLE Genes involved in Activated AMPK stimulates fatty-acid oxidation in muscle
0.0 0.2 REACTOME APOPTOSIS INDUCED DNA FRAGMENTATION Genes involved in Apoptosis induced DNA fragmentation
0.0 0.4 REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS Genes involved in Cell-extracellular matrix interactions
0.0 0.3 REACTOME REGULATION OF PYRUVATE DEHYDROGENASE PDH COMPLEX Genes involved in Regulation of pyruvate dehydrogenase (PDH) complex
0.0 0.2 REACTOME SPRY REGULATION OF FGF SIGNALING Genes involved in Spry regulation of FGF signaling
0.0 0.1 REACTOME RAF MAP KINASE CASCADE Genes involved in RAF/MAP kinase cascade
0.0 0.2 REACTOME NA CL DEPENDENT NEUROTRANSMITTER TRANSPORTERS Genes involved in Na+/Cl- dependent neurotransmitter transporters
0.0 0.2 REACTOME REGULATION OF SIGNALING BY CBL Genes involved in Regulation of signaling by CBL
0.0 0.1 REACTOME PYRIMIDINE CATABOLISM Genes involved in Pyrimidine catabolism