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PRJNA195909:zebrafish embryo and larva development
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Results for nr2f2
Z-value: 1.37
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Transcription factors associated with nr2f2
Activity-expression correlation:
| Gene | Promoter | Pearson corr. coef. | P-value | Plot |
|---|---|---|---|---|
| nr2f2 | dr11_v1_chr18_-_23875370_23875370 | -0.88 | 1.6e-03 | Click! |
| Promoter | Log-likelihood | Transcript | Gene | Gene Info |
|---|---|---|---|---|
| chr10_-_21542702 Show fit | 3.67 |
ENSDART00000146761
ENSDART00000134502 |
zgc:165539 |
|
| chr18_-_43866526 Show fit | 3.15 |
ENSDART00000111309
|
trehalase (brush-border membrane glycoprotein) |
|
| chr10_+_19569052 Show fit | 3.12 |
ENSDART00000058425
|
|
|
| chr19_-_27564458 Show fit | 3.06 |
ENSDART00000123155
|
si:dkeyp-46h3.6 |
|
| chr17_-_2590222 Show fit | 2.66 |
ENSDART00000185711
|
|
|
| chr17_-_2573021 Show fit | 2.55 |
ENSDART00000074181
|
zona pellucida glycoprotein 3, tandem duplicate 2 |
|
| chr17_-_2595736 Show fit | 2.52 |
ENSDART00000128797
|
zona pellucida glycoprotein 3, tandem duplicate 2 |
|
| chr17_-_2578026 Show fit | 2.50 |
ENSDART00000065821
|
zona pellucida glycoprotein 3, tandem duplicate 2 |
|
| chr1_+_24387659 Show fit | 2.27 |
ENSDART00000130356
|
quinoid dihydropteridine reductase b2 |
|
| chr18_-_43866001 Show fit | 2.25 |
ENSDART00000150218
|
trehalase (brush-border membrane glycoprotein) |
Network of associatons between targets according to the STRING database.
First level regulatory network of nr2f2
Gene Ontology Analysis
Gene overrepresentation in biological process category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.5 | 9.2 | GO:0007339 | binding of sperm to zona pellucida(GO:0007339) egg coat formation(GO:0035803) regulation of acrosome reaction(GO:0060046) positive regulation of acrosome reaction(GO:2000344) |
| 1.8 | 5.4 | GO:0005991 | trehalose metabolic process(GO:0005991) |
| 0.2 | 2.3 | GO:0006729 | tetrahydrobiopterin biosynthetic process(GO:0006729) tetrahydrobiopterin metabolic process(GO:0046146) |
| 0.2 | 2.0 | GO:0006363 | termination of RNA polymerase I transcription(GO:0006363) |
| 0.1 | 1.8 | GO:0000463 | maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000463) |
| 0.0 | 1.6 | GO:0006998 | nuclear envelope organization(GO:0006998) |
| 0.1 | 1.5 | GO:0043928 | exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay(GO:0043928) |
| 0.0 | 1.5 | GO:0032200 | telomere maintenance(GO:0000723) telomere organization(GO:0032200) |
| 0.2 | 1.4 | GO:0040038 | meiotic cytokinesis(GO:0033206) polar body extrusion after meiotic divisions(GO:0040038) |
| 0.1 | 1.4 | GO:0006798 | polyphosphate metabolic process(GO:0006797) polyphosphate catabolic process(GO:0006798) |
Gene overrepresentation in cellular component category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 3.8 | GO:0005730 | nucleolus(GO:0005730) |
| 0.6 | 1.8 | GO:0070545 | PeBoW complex(GO:0070545) |
| 0.0 | 1.8 | GO:0000781 | chromosome, telomeric region(GO:0000781) |
| 0.1 | 1.6 | GO:0034992 | microtubule organizing center attachment site(GO:0034992) LINC complex(GO:0034993) |
| 0.1 | 1.5 | GO:0030015 | CCR4-NOT core complex(GO:0030015) |
| 0.0 | 1.1 | GO:0030496 | midbody(GO:0030496) |
| 0.1 | 1.0 | GO:0042788 | polysomal ribosome(GO:0042788) |
| 0.3 | 0.9 | GO:1990415 | Pex17p-Pex14p docking complex(GO:1990415) peroxisomal importomer complex(GO:1990429) |
| 0.1 | 0.9 | GO:0035517 | PR-DUB complex(GO:0035517) |
| 0.1 | 0.9 | GO:0017119 | Golgi transport complex(GO:0017119) |
Gene overrepresentation in molecular function category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.8 | 9.2 | GO:0035804 | structural constituent of egg coat(GO:0035804) |
| 1.8 | 5.4 | GO:0004555 | alpha,alpha-trehalase activity(GO:0004555) trehalase activity(GO:0015927) |
| 0.0 | 4.6 | GO:0030246 | carbohydrate binding(GO:0030246) |
| 0.6 | 2.3 | GO:0070404 | 6,7-dihydropteridine reductase activity(GO:0004155) NADH binding(GO:0070404) |
| 0.0 | 1.8 | GO:0043021 | ribonucleoprotein complex binding(GO:0043021) |
| 0.1 | 1.7 | GO:0015248 | sterol transporter activity(GO:0015248) |
| 0.1 | 1.6 | GO:0043495 | protein anchor(GO:0043495) |
| 0.0 | 1.6 | GO:0016811 | hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides(GO:0016811) |
| 0.1 | 1.5 | GO:0004535 | poly(A)-specific ribonuclease activity(GO:0004535) |
| 0.1 | 1.4 | GO:0004309 | exopolyphosphatase activity(GO:0004309) |
Gene overrepresentation in curated gene sets: canonical pathways category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 1.2 | PID EPHRINB REV PATHWAY | Ephrin B reverse signaling |
| 0.0 | 1.2 | ST GA13 PATHWAY | G alpha 13 Pathway |
| 0.0 | 1.1 | PID PS1 PATHWAY | Presenilin action in Notch and Wnt signaling |
| 0.0 | 1.1 | PID P73PATHWAY | p73 transcription factor network |
| 0.0 | 1.0 | PID P38 ALPHA BETA DOWNSTREAM PATHWAY | Signaling mediated by p38-alpha and p38-beta |
| 0.0 | 0.9 | PID AR PATHWAY | Coregulation of Androgen receptor activity |
| 0.0 | 0.7 | PID P38 MK2 PATHWAY | p38 signaling mediated by MAPKAP kinases |
| 0.0 | 0.7 | PID HDAC CLASSII PATHWAY | Signaling events mediated by HDAC Class II |
| 0.0 | 0.5 | PID ALK1 PATHWAY | ALK1 signaling events |
| 0.0 | 0.5 | PID ATR PATHWAY | ATR signaling pathway |
Gene overrepresentation in curated gene sets: REACTOME pathways category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.9 | 5.4 | REACTOME DIGESTION OF DIETARY CARBOHYDRATE | Genes involved in Digestion of dietary carbohydrate |
| 0.1 | 1.5 | REACTOME DEADENYLATION OF MRNA | Genes involved in Deadenylation of mRNA |
| 0.0 | 1.4 | REACTOME MYOGENESIS | Genes involved in Myogenesis |
| 0.1 | 1.1 | REACTOME SEMA4D IN SEMAPHORIN SIGNALING | Genes involved in Sema4D in semaphorin signaling |
| 0.0 | 1.1 | REACTOME ACTIVATION OF CHAPERONE GENES BY XBP1S | Genes involved in Activation of Chaperone Genes by XBP1(S) |
| 0.1 | 0.9 | REACTOME SYNTHESIS OF VERY LONG CHAIN FATTY ACYL COAS | Genes involved in Synthesis of very long-chain fatty acyl-CoAs |
| 0.0 | 0.8 | REACTOME SPHINGOLIPID DE NOVO BIOSYNTHESIS | Genes involved in Sphingolipid de novo biosynthesis |
| 0.1 | 0.7 | REACTOME TANDEM PORE DOMAIN POTASSIUM CHANNELS | Genes involved in Tandem pore domain potassium channels |
| 0.1 | 0.7 | REACTOME REVERSIBLE HYDRATION OF CARBON DIOXIDE | Genes involved in Reversible Hydration of Carbon Dioxide |
| 0.0 | 0.7 | REACTOME REGULATION OF GENE EXPRESSION IN BETA CELLS | Genes involved in Regulation of gene expression in beta cells |