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PRJNA195909:zebrafish embryo and larva development

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Results for nr2f1b+nr2f5

Z-value: 0.55

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Transcription factors associated with nr2f1b+nr2f5

Gene Symbol Gene ID Gene Info
ENSDARG00000017168 nuclear receptor subfamily 2, group F, member 1b
ENSDARG00000033172 nuclear receptor subfamily 2, group F, member 5

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
nr2f5dr11_v1_chr16_+_46294337_462943370.511.6e-01Click!
nr2f1bdr11_v1_chr10_+_43797130_43797130-0.117.8e-01Click!

Activity profile of nr2f1b+nr2f5 motif

Sorted Z-values of nr2f1b+nr2f5 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr22_+_37888249 0.60 ENSDART00000076082
fetuin B
chr7_-_2039060 0.49 ENSDART00000173879
si:cabz01007794.1
chr20_-_16906623 0.45 ENSDART00000012859
ENSDART00000171628
proteasome subunit alpha 6b
chr21_+_25688388 0.43 ENSDART00000125709
bicaudal-D-related protein 2
chr2_+_52847049 0.37 ENSDART00000121980
cAMP responsive element binding protein 3-like 3b
chr13_-_23007813 0.33 ENSDART00000057638
hexokinase 1
chr5_+_54400971 0.30 ENSDART00000169695
B-box and SPRY domain containing
chr2_+_58841181 0.27 ENSDART00000164102
cold inducible RNA binding protein a
chr4_+_1530287 0.25 ENSDART00000067446
solute carrier family 38, member 4
chr5_+_64856666 0.25 ENSDART00000050863
zgc:101858
chr1_-_55840105 0.24 ENSDART00000137909
sterile alpha motif domain containing 1b
chr22_-_26834043 0.23 ENSDART00000087202
si:dkey-44g23.5
chr14_-_5817039 0.23 ENSDART00000131820
Kazal-type serine peptidase inhibitor domain 2
chr15_+_27364394 0.21 ENSDART00000122101
T-box 2b
chr20_-_11178022 0.19 ENSDART00000152246
fibronectin leucine rich transmembrane protein 2
chr17_+_389218 0.19 ENSDART00000162898
si:rp71-62i8.1
chr2_+_16449627 0.18 ENSDART00000005381
zgc:110269
chr17_+_17955063 0.17 ENSDART00000104999
coiled-coil domain containing 85C, a
chr1_-_20824411 0.16 ENSDART00000182810
tolloid-like 1
chr1_+_59154521 0.16 ENSDART00000130089
ENSDART00000152456
heme-binding protein soul5, like
chr2_-_9607879 0.16 ENSDART00000056899
thioredoxin domain containing 12 (endoplasmic reticulum)
chr24_+_37700259 0.15 ENSDART00000066556
zmp:0000000624
chr2_+_33382648 0.15 ENSDART00000137207
ENSDART00000098831
solute carrier family 6 (neurotransmitter transporter, glycine), member 9
chr6_+_9677420 0.15 ENSDART00000064995
small ubiquitin-like modifier 1
chr24_-_21989406 0.14 ENSDART00000032963
apolipoprotein O, b
chr8_-_41273768 0.14 ENSDART00000108518
ring finger protein 10
chr19_+_26828502 0.13 ENSDART00000183654
ENSDART00000126006
ENSDART00000185341

chr3_-_12970418 0.13 ENSDART00000158747
platelet-derived growth factor alpha polypeptide b
chr8_-_41273461 0.13 ENSDART00000190598
ring finger protein 10
chr10_-_29831944 0.12 ENSDART00000063923
ENSDART00000136264
ZPR1 zinc finger
chr3_-_19517462 0.12 ENSDART00000162027

chr14_-_24391424 0.12 ENSDART00000113376
ENSDART00000126894
family with sequence similarity 13, member B
chr4_-_2440175 0.12 ENSDART00000058059
oxysterol binding protein like 8
chr2_+_43750899 0.11 ENSDART00000135836
Rho GTPase activating protein 12a
chr23_+_31245395 0.11 ENSDART00000053588
interleukin-1 receptor-associated kinase 1 binding protein 1
chr20_+_43925266 0.10 ENSDART00000037379
chloride intracellular channel 5b
chr20_+_25581627 0.10 ENSDART00000030229
cytochrome P450, family 2, subfamily P, polypeptide 9
chr3_+_41917499 0.10 ENSDART00000028673
LFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase
chr2_+_21605547 0.10 ENSDART00000112014
M-phase specific PLK1 interacting protein
chr2_+_3696038 0.10 ENSDART00000150499
ENSDART00000136906
ENSDART00000164152
ENSDART00000128514
ENSDART00000108964
epidermal growth factor receptor a (erythroblastic leukemia viral (v-erb-b) oncogene homolog, avian)
chr4_+_76441823 0.10 ENSDART00000163932
si:dkey-16p6.1
chr4_+_3980247 0.09 ENSDART00000049194
G protein-coupled receptor 37b
chr22_-_31788170 0.08 ENSDART00000170925
Pim proto-oncogene, serine/threonine kinase, related 207
chr13_+_24834199 0.08 ENSDART00000101274
zgc:153981
chr8_+_23711842 0.07 ENSDART00000128783
peroxisome proliferator-activated receptor delta b
chr1_-_26544268 0.07 ENSDART00000152117
si:ch211-202n12.2
chr4_+_1722899 0.06 ENSDART00000021139
FGFR1 oncogene partner 2
chr24_+_42127983 0.06 ENSDART00000190157
ENSDART00000176032
ENSDART00000175790
WW domain containing E3 ubiquitin protein ligase 1
chr11_-_34147205 0.06 ENSDART00000173216
ATPase 13A3
chr15_-_34933560 0.06 ENSDART00000006288
DEAH (Asp-Glu-Ala-His) box polypeptide 16
chr18_-_6975175 0.06 ENSDART00000134194
si:dkey-266m15.6
chr7_+_4474880 0.06 ENSDART00000143528
si:dkey-83f18.14
chr24_-_21991770 0.06 ENSDART00000147296
si:rp71-1f1.4
chr2_+_56213694 0.05 ENSDART00000162582
upf1 regulator of nonsense transcripts homolog (yeast)
chr19_-_48039400 0.05 ENSDART00000166748
ENSDART00000165921
colony stimulating factor 3 (granulocyte) b
chr19_+_5291935 0.05 ENSDART00000141237
si:dkeyp-113d7.10
chr1_+_144284 0.05 ENSDART00000064061
protein Z, vitamin K-dependent plasma glycoprotein b
chr18_-_27316599 0.05 ENSDART00000028294
zgc:56106
chr8_-_13428740 0.04 ENSDART00000131826

chr24_+_42132962 0.04 ENSDART00000187739
WW domain containing E3 ubiquitin protein ligase 1
chr1_-_40132831 0.04 ENSDART00000135647
si:ch211-113e8.10
chr2_+_2904080 0.04 ENSDART00000110416
eukaryotic translation initiation factor 2B, subunit 5 epsilon
chr18_+_7073130 0.03 ENSDART00000101216
ENSDART00000148947
si:dkey-88e18.2
chr16_+_20895904 0.03 ENSDART00000052662
homeobox A13b
chr25_-_10791437 0.03 ENSDART00000127054

chr7_+_27251376 0.03 ENSDART00000173521
ENSDART00000173962
SRY (sex determining region Y)-box 6
chr12_+_7491690 0.03 ENSDART00000152564
phytanoyl-CoA 2-hydroxylase interacting protein-like b
chr19_+_7506380 0.02 ENSDART00000182837
papillary renal cell carcinoma (translocation-associated)
chr10_-_21054059 0.02 ENSDART00000139733
protocadherin 1a
chr17_+_14711765 0.02 ENSDART00000012889
connexin 28.6
chr18_+_3338228 0.02 ENSDART00000161520
glycerophosphodiester phosphodiesterase domain containing 4a
chr2_-_1468258 0.02 ENSDART00000114431
glycosylphosphatidylinositol anchor attachment 1
chr13_-_50546634 0.02 ENSDART00000192127

chr6_+_103361 0.02 ENSDART00000151899
low density lipoprotein receptor b
chr8_-_13419049 0.02 ENSDART00000133656
Pim proto-oncogene, serine/threonine kinase, related 101
chr8_-_13471916 0.02 ENSDART00000146558
Pim proto-oncogene, serine/threonine kinase, related 105
chr8_-_13486258 0.01 ENSDART00000137459
Pim proto-oncogene, serine/threonine kinase, related 104
chr7_+_29153018 0.01 ENSDART00000138065
transmembrane protein with metallophosphoesterase domain
chr1_-_47771742 0.01 ENSDART00000101079
neuralized E3 ubiquitin protein ligase 1Aa
chr24_+_42117231 0.01 ENSDART00000067734
sorting nexin 16
chr17_+_5351922 0.01 ENSDART00000105394
runt-related transcription factor 2a
chr15_-_41756454 0.01 ENSDART00000139498
ENSDART00000099302
finTRIM family, member 72
chr8_+_36803415 0.01 ENSDART00000111680
IQ motif and Sec7 domain 2b
chr25_+_1549838 0.00 ENSDART00000115001
arginine vasopressin receptor 1Aa
chr20_+_53577502 0.00 ENSDART00000126983
myosin, heavy chain 6, cardiac muscle, alpha

Network of associatons between targets according to the STRING database.

First level regulatory network of nr2f1b+nr2f5

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.4 GO:0055107 Golgi to secretory granule transport(GO:0055107)
0.1 0.2 GO:0072068 distal convoluted tubule development(GO:0072025) late distal convoluted tubule development(GO:0072068)
0.0 0.2 GO:0035124 embryonic caudal fin morphogenesis(GO:0035124)
0.0 0.1 GO:0060092 regulation of synaptic transmission, glycinergic(GO:0060092)
0.0 0.1 GO:0071276 cellular response to cadmium ion(GO:0071276)
0.0 0.3 GO:0031643 positive regulation of myelination(GO:0031643)
0.0 0.2 GO:0061687 detoxification of inorganic compound(GO:0061687)
0.0 0.3 GO:0001678 cellular glucose homeostasis(GO:0001678)
0.0 0.1 GO:0055016 hypochord development(GO:0055016)
0.0 0.3 GO:0048026 positive regulation of mRNA splicing, via spliceosome(GO:0048026)
0.0 0.1 GO:0031954 positive regulation of protein autophosphorylation(GO:0031954)
0.0 0.4 GO:0010499 proteasomal ubiquitin-independent protein catabolic process(GO:0010499)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.4 GO:0019773 proteasome core complex, alpha-subunit complex(GO:0019773)
0.0 0.2 GO:0005614 interstitial matrix(GO:0005614)
0.0 0.1 GO:0061617 MICOS complex(GO:0061617)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.3 GO:0008865 glucokinase activity(GO:0004340) hexokinase activity(GO:0004396) glucose binding(GO:0005536) fructokinase activity(GO:0008865) mannokinase activity(GO:0019158)
0.0 0.2 GO:0047134 protein-disulfide reductase activity(GO:0047134)
0.0 0.1 GO:0005006 epidermal growth factor-activated receptor activity(GO:0005006)
0.0 0.1 GO:0033829 O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase activity(GO:0033829)
0.0 0.2 GO:0004523 RNA-DNA hybrid ribonuclease activity(GO:0004523)
0.0 0.4 GO:0035497 cAMP response element binding(GO:0035497)
0.0 0.6 GO:0004869 cysteine-type endopeptidase inhibitor activity(GO:0004869)
0.0 0.1 GO:0005161 platelet-derived growth factor receptor binding(GO:0005161)
0.0 0.1 GO:0015187 glycine transmembrane transporter activity(GO:0015187)

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.1 REACTOME REGULATION OF IFNG SIGNALING Genes involved in Regulation of IFNG signaling
0.0 0.1 REACTOME NA CL DEPENDENT NEUROTRANSMITTER TRANSPORTERS Genes involved in Na+/Cl- dependent neurotransmitter transporters
0.0 0.3 REACTOME AMINO ACID TRANSPORT ACROSS THE PLASMA MEMBRANE Genes involved in Amino acid transport across the plasma membrane