Project
PRJNA195909:zebrafish embryo and larva development
Navigation
Downloads
Results for nkx3-1
Z-value: 1.90
Motif logo
Transcription factors associated with nkx3-1
Activity-expression correlation:
| Gene | Promoter | Pearson corr. coef. | P-value | Plot |
|---|---|---|---|---|
| nkx3-1 | dr11_v1_chr8_-_50259448_50259448 | -0.76 | 1.8e-02 | Click! |
| Promoter | Log-likelihood | Transcript | Gene | Gene Info |
|---|---|---|---|---|
| chr10_-_34915886 Show fit | 6.23 |
ENSDART00000141201
ENSDART00000002166 |
cyclin A1 |
|
| chr22_+_25236657 Show fit | 5.75 |
ENSDART00000138012
|
zgc:172218 |
|
| chr22_+_25249193 Show fit | 5.64 |
ENSDART00000171851
|
si:ch211-226h8.11 |
|
| chr9_+_8396755 Show fit | 5.30 |
ENSDART00000043067
|
zgc:171776 |
|
| chr10_-_34916208 Show fit | 5.29 |
ENSDART00000187371
|
cyclin A1 |
|
| chr9_+_44994214 Show fit | 4.08 |
ENSDART00000141434
|
retinol saturase (all-trans-retinol 13,14-reductase) like |
|
| chr7_+_17947217 Show fit | 3.71 |
ENSDART00000101601
|
cysteine three histidine 1 |
|
| chr16_+_54641230 Show fit | 3.50 |
ENSDART00000157641
ENSDART00000159540 |
F-box protein 43 |
|
| chr15_+_29025090 Show fit | 2.91 |
ENSDART00000131755
|
si:ch211-137a8.2 |
|
| chr9_-_12888082 Show fit | 2.83 |
ENSDART00000133135
ENSDART00000134415 |
si:ch211-167j6.3 |
Network of associatons between targets according to the STRING database.
First level regulatory network of nkx3-1
Gene Ontology Analysis
Gene overrepresentation in biological process category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.2 | 9.2 | GO:0000079 | regulation of cyclin-dependent protein serine/threonine kinase activity(GO:0000079) regulation of cyclin-dependent protein kinase activity(GO:1904029) |
| 1.2 | 4.6 | GO:0030718 | germ-line stem cell population maintenance(GO:0030718) |
| 0.1 | 4.5 | GO:0048264 | determination of ventral identity(GO:0048264) |
| 0.4 | 3.5 | GO:0045835 | negative regulation of meiotic nuclear division(GO:0045835) |
| 0.2 | 2.4 | GO:0006611 | protein export from nucleus(GO:0006611) |
| 0.1 | 2.3 | GO:0006506 | GPI anchor biosynthetic process(GO:0006506) |
| 0.1 | 2.3 | GO:0006891 | intra-Golgi vesicle-mediated transport(GO:0006891) |
| 0.1 | 2.3 | GO:0046847 | filopodium assembly(GO:0046847) |
| 0.6 | 1.9 | GO:0010847 | regulation of chromatin assembly(GO:0010847) |
| 0.3 | 1.9 | GO:0006013 | mannose metabolic process(GO:0006013) |
Gene overrepresentation in cellular component category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 3.8 | 11.5 | GO:0097124 | cyclin A2-CDK2 complex(GO:0097124) |
| 0.1 | 3.1 | GO:0071141 | SMAD protein complex(GO:0071141) |
| 0.2 | 2.9 | GO:0034992 | microtubule organizing center attachment site(GO:0034992) LINC complex(GO:0034993) |
| 0.5 | 2.7 | GO:1990923 | PET complex(GO:1990923) |
| 0.1 | 2.5 | GO:0032420 | stereocilium(GO:0032420) |
| 0.1 | 2.4 | GO:0005689 | U12-type spliceosomal complex(GO:0005689) |
| 0.4 | 2.3 | GO:0000506 | glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex(GO:0000506) |
| 0.2 | 2.2 | GO:0017119 | Golgi transport complex(GO:0017119) |
| 0.0 | 2.2 | GO:0032580 | Golgi cisterna membrane(GO:0032580) |
| 0.1 | 2.0 | GO:0043186 | P granule(GO:0043186) |
Gene overrepresentation in molecular function category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.1 | 18.3 | GO:0030246 | carbohydrate binding(GO:0030246) |
| 0.1 | 9.2 | GO:0016538 | cyclin-dependent protein serine/threonine kinase regulator activity(GO:0016538) |
| 0.0 | 3.9 | GO:0005085 | guanyl-nucleotide exchange factor activity(GO:0005085) |
| 0.3 | 2.7 | GO:0034584 | piRNA binding(GO:0034584) |
| 0.4 | 2.3 | GO:0017176 | phosphatidylinositol N-acetylglucosaminyltransferase activity(GO:0017176) |
| 0.0 | 2.0 | GO:0003727 | single-stranded RNA binding(GO:0003727) |
| 0.4 | 1.9 | GO:0001042 | RNA polymerase I core binding(GO:0001042) |
| 0.1 | 1.9 | GO:0004559 | alpha-mannosidase activity(GO:0004559) |
| 0.1 | 1.7 | GO:0004383 | guanylate cyclase activity(GO:0004383) |
| 0.5 | 1.6 | GO:0016300 | tRNA (uracil) methyltransferase activity(GO:0016300) |
Gene overrepresentation in curated gene sets: canonical pathways category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.7 | 11.5 | SA REG CASCADE OF CYCLIN EXPR | Expression of cyclins regulates progression through the cell cycle by activating cyclin-dependent kinases. |
| 0.1 | 2.1 | PID ATM PATHWAY | ATM pathway |
| 0.1 | 1.8 | SIG REGULATION OF THE ACTIN CYTOSKELETON BY RHO GTPASES | Genes related to regulation of the actin cytoskeleton |
| 0.1 | 1.3 | PID RANBP2 PATHWAY | Sumoylation by RanBP2 regulates transcriptional repression |
| 0.1 | 1.2 | PID ARF 3PATHWAY | Arf1 pathway |
| 0.0 | 1.2 | PID TNF PATHWAY | TNF receptor signaling pathway |
| 0.0 | 1.0 | PID KIT PATHWAY | Signaling events mediated by Stem cell factor receptor (c-Kit) |
| 0.0 | 0.9 | PID ILK PATHWAY | Integrin-linked kinase signaling |
| 0.0 | 0.8 | PID DELTA NP63 PATHWAY | Validated transcriptional targets of deltaNp63 isoforms |
| 0.0 | 0.7 | PID INSULIN GLUCOSE PATHWAY | Insulin-mediated glucose transport |
Gene overrepresentation in curated gene sets: REACTOME pathways category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.7 | 11.5 | REACTOME CYCLIN A B1 ASSOCIATED EVENTS DURING G2 M TRANSITION | Genes involved in Cyclin A/B1 associated events during G2/M transition |
| 0.1 | 2.3 | REACTOME SYNTHESIS OF GLYCOSYLPHOSPHATIDYLINOSITOL GPI | Genes involved in Synthesis of glycosylphosphatidylinositol (GPI) |
| 0.1 | 2.2 | REACTOME N GLYCAN ANTENNAE ELONGATION IN THE MEDIAL TRANS GOLGI | Genes involved in N-glycan antennae elongation in the medial/trans-Golgi |
| 0.1 | 1.9 | REACTOME GLYCOSPHINGOLIPID METABOLISM | Genes involved in Glycosphingolipid metabolism |
| 0.1 | 1.8 | REACTOME ACTIVATION OF RAC | Genes involved in Activation of Rac |
| 0.0 | 1.8 | REACTOME MRNA SPLICING MINOR PATHWAY | Genes involved in mRNA Splicing - Minor Pathway |
| 0.2 | 1.4 | REACTOME G2 M DNA DAMAGE CHECKPOINT | Genes involved in G2/M DNA damage checkpoint |
| 0.1 | 1.4 | REACTOME ENOS ACTIVATION AND REGULATION | Genes involved in eNOS activation and regulation |
| 0.0 | 1.4 | REACTOME SPHINGOLIPID METABOLISM | Genes involved in Sphingolipid metabolism |
| 0.2 | 1.3 | REACTOME SYNTHESIS OF VERY LONG CHAIN FATTY ACYL COAS | Genes involved in Synthesis of very long-chain fatty acyl-CoAs |