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PRJNA195909:zebrafish embryo and larva development

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Results for nkx1.2la

Z-value: 1.38

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Transcription factors associated with nkx1.2la

Gene Symbol Gene ID Gene Info
nkx1.2la
ENSDARG00000006350 NK1 transcription factor related 2-like,a

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
nkx1.2ladr11_v1_chr13_+_40770628_407706280.098.2e-01Click!

Activity profile of nkx1.2la motif

Sorted Z-values of nkx1.2la motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr16_+_23984179 2.94 ENSDART00000175879
apoc2
apolipoprotein C-II
chr4_-_9891874 2.94 ENSDART00000067193
adm2a
adrenomedullin 2a
chr25_+_29160102 2.81 ENSDART00000162854
pkmb
pyruvate kinase M1/2b
chr8_+_16025554 2.67 ENSDART00000110171
elavl4
ELAV like neuron-specific RNA binding protein 4
chr4_+_16885854 2.39 ENSDART00000017726
etnk1
ethanolamine kinase 1
chr21_-_43015383 2.38 ENSDART00000065097
dpysl3
dihydropyrimidinase-like 3
chr15_+_23799461 2.32 ENSDART00000154885
si:ch211-167j9.4
si:ch211-167j9.4
chr16_-_20312146 2.12 ENSDART00000134980
si:dkeyp-86h10.3
si:dkeyp-86h10.3
chr23_+_19813677 2.11 ENSDART00000139192
ENSDART00000142308
emd
emerin (Emery-Dreifuss muscular dystrophy)
chr13_-_9886579 2.09 ENSDART00000101926
si:ch211-117n7.7
si:ch211-117n7.7
chr7_+_59020972 1.93 ENSDART00000157873
hacd1
3-hydroxyacyl-CoA dehydratase 1
chr4_+_9669717 1.85 ENSDART00000004604
si:dkey-153k10.9
si:dkey-153k10.9
chr21_+_6751405 1.82 ENSDART00000037265
ENSDART00000146371
olfm1b
olfactomedin 1b
chr23_-_15216654 1.82 ENSDART00000131649
sulf2b
sulfatase 2b
chr21_+_6751760 1.81 ENSDART00000135914
olfm1b
olfactomedin 1b
chr5_-_51619742 1.74 ENSDART00000188537
otpb
orthopedia homeobox b
chr13_+_35339182 1.68 ENSDART00000019323
jag1b
jagged 1b
chr4_+_21129752 1.62 ENSDART00000169764
syt1a
synaptotagmin Ia
chr20_+_19512727 1.61 ENSDART00000063696
atraid
all-trans retinoic acid-induced differentiation factor
chr15_-_5815006 1.58 ENSDART00000102459
rbp2a
retinol binding protein 2a, cellular
chr6_+_57541776 1.54 ENSDART00000157330
necab3
N-terminal EF-hand calcium binding protein 3
chr8_-_15129573 1.53 ENSDART00000142358
bcar3
BCAR3, NSP family adaptor protein
chr25_+_11008419 1.50 ENSDART00000156589
mhc1lia
major histocompatibility complex class I LIA
chr17_-_49978986 1.50 ENSDART00000154728
col12a1a
collagen, type XII, alpha 1a
chr8_+_25079470 1.49 ENSDART00000000744
sypl2b
synaptophysin-like 2b
chr17_-_12385308 1.40 ENSDART00000080927
snap25b
synaptosomal-associated protein, 25b
chr18_+_21408794 1.37 ENSDART00000140161
necab2
N-terminal EF-hand calcium binding protein 2
chr20_+_43925266 1.37 ENSDART00000037379
clic5b
chloride intracellular channel 5b
chr14_-_413273 1.36 ENSDART00000163976
ENSDART00000179907
FAT4
FAT atypical cadherin 4
chr2_-_38000276 1.34 ENSDART00000034790
pcp4l1
Purkinje cell protein 4 like 1
chr6_-_7720332 1.30 ENSDART00000135945
rpsa
ribosomal protein SA
chr7_+_6652967 1.28 ENSDART00000102681
pnp5a
purine nucleoside phosphorylase 5a
chr24_+_38301080 1.26 ENSDART00000105672
mybpc2b
myosin binding protein C, fast type b
chr21_+_28478663 1.26 ENSDART00000077887
ENSDART00000134150
slc22a6l
solute carrier family 22 (organic anion transporter), member 6, like
chr23_+_43255328 1.22 ENSDART00000102712
tgm2a
transglutaminase 2, C polypeptide A
chr17_+_43032529 1.22 ENSDART00000055611
ENSDART00000154863
isca2
iron-sulfur cluster assembly 2
chr10_-_40968095 1.20 ENSDART00000184104
npffr1l1
neuropeptide FF receptor 1 like 1
chr8_+_23521974 1.19 ENSDART00000188130
ENSDART00000129378
sema3gb
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3Gb
chr11_-_30158191 1.18 ENSDART00000155278
ENSDART00000156121
scml2
Scm polycomb group protein like 2
chr10_+_37137464 1.17 ENSDART00000114909
cuedc1a
CUE domain containing 1a
chr5_+_22969651 1.16 ENSDART00000089992
ENSDART00000145477
hmgn7
high mobility group nucleosomal binding domain 7
chr23_+_28582865 1.15 ENSDART00000020296
l1cama
L1 cell adhesion molecule, paralog a
chr20_+_28861435 1.13 ENSDART00000142678
slc10a1
solute carrier family 10 (sodium/bile acid cotransporter), member 1
chr11_+_30057762 1.11 ENSDART00000164139
nhsb
Nance-Horan syndrome b (congenital cataracts and dental anomalies)
chr1_-_50859053 1.09 ENSDART00000132779
ENSDART00000137648
si:dkeyp-123h10.2
si:dkeyp-123h10.2
chr17_+_21964472 1.04 ENSDART00000063704
ENSDART00000188904
crip3
cysteine-rich protein 3
chr3_-_12930217 1.02 ENSDART00000166322
pdgfab
platelet-derived growth factor alpha polypeptide b
chr6_+_7421898 0.99 ENSDART00000043946
ccdc65
coiled-coil domain containing 65
chr1_+_44127292 0.97 ENSDART00000160542
cabp2a
calcium binding protein 2a
chr24_-_21689146 0.96 ENSDART00000105917
urad
ureidoimidazoline (2-oxo-4-hydroxy-4-carboxy-5-) decarboxylase
chr19_+_43780970 0.94 ENSDART00000063870
rpl11
ribosomal protein L11
chr15_+_9327252 0.94 ENSDART00000144381
sgcg
sarcoglycan, gamma
chr14_+_5385855 0.92 ENSDART00000031508
lbx2
ladybird homeobox 2
chr20_+_28861629 0.91 ENSDART00000187274
ENSDART00000047826
slc10a1
solute carrier family 10 (sodium/bile acid cotransporter), member 1
chr4_+_6032640 0.89 ENSDART00000157487
tfec
transcription factor EC
chr8_+_18588551 0.88 ENSDART00000177476
ENSDART00000063539
prrg1
proline rich Gla (G-carboxyglutamic acid) 1
chr24_-_31425799 0.87 ENSDART00000157998
cngb3.1
cyclic nucleotide gated channel beta 3, tandem duplicate 1
chr11_-_30634286 0.87 ENSDART00000191019
zgc:153665
zgc:153665
chr23_-_20051369 0.87 ENSDART00000049836
bgnb
biglycan b
chr4_+_9400012 0.81 ENSDART00000191960
tmtc1
transmembrane and tetratricopeptide repeat containing 1
chr21_-_19314618 0.80 ENSDART00000188744
gpat3
glycerol-3-phosphate acyltransferase 3
chr24_-_36680261 0.77 ENSDART00000059507
ccr10
chemokine (C-C motif) receptor 10
chr18_+_24919614 0.76 ENSDART00000008638
rgma
repulsive guidance molecule family member a
chr15_-_14552101 0.75 ENSDART00000171169
numbl
numb homolog (Drosophila)-like
chr2_+_50608099 0.74 ENSDART00000185805
ENSDART00000111135
neurod6b
neuronal differentiation 6b
chr19_+_12237945 0.72 ENSDART00000190034
grhl2b
grainyhead-like transcription factor 2b
chr1_+_51721851 0.70 ENSDART00000040397
prdx2
peroxiredoxin 2
chr7_+_54642005 0.69 ENSDART00000171864
fgf19
fibroblast growth factor 19
chr5_+_1079423 0.65 ENSDART00000172231
si:zfos-128g4.2
si:zfos-128g4.2
chr15_+_45640906 0.64 ENSDART00000149361
ENSDART00000149079
sagb
S-antigen; retina and pineal gland (arrestin) b
chr22_-_26865361 0.64 ENSDART00000182504
hmox2a
heme oxygenase 2a
chr11_-_21528056 0.63 ENSDART00000181626
srgap2
SLIT-ROBO Rho GTPase activating protein 2
chr16_-_11798994 0.63 ENSDART00000135408
cnfn
cornifelin
chr25_+_19489370 0.62 ENSDART00000091132
glsl
glutaminase like
chr8_+_52637507 0.61 ENSDART00000163830
si:dkey-90l8.3
si:dkey-90l8.3
chr19_-_5669122 0.60 ENSDART00000112211
si:ch211-264f5.2
si:ch211-264f5.2
chr12_+_695619 0.60 ENSDART00000161691
abcc3
ATP-binding cassette, sub-family C (CFTR/MRP), member 3
chr22_+_9939901 0.58 ENSDART00000169777
ENSDART00000081420
zgc:171686
zgc:171686
chr10_-_5581487 0.56 ENSDART00000141943
syk
spleen tyrosine kinase
chr11_+_16153207 0.55 ENSDART00000192356
tada3l
transcriptional adaptor 3 (NGG1 homolog, yeast)-like
chr7_+_34620418 0.55 ENSDART00000081338
slc9a5
solute carrier family 9, subfamily A (NHE5, cation proton antiporter 5), member 5
chr4_+_5255041 0.53 ENSDART00000137966
ccdc167
coiled-coil domain containing 167
chr18_+_49969568 0.52 ENSDART00000126916
mob2b
MOB kinase activator 2b
chr1_-_19502322 0.50 ENSDART00000181888
ENSDART00000044030
kitb
v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog b
chr20_-_13774826 0.50 ENSDART00000063831
opn8c
opsin 8, group member c
chr6_+_28051978 0.49 ENSDART00000143218
si:ch73-194h10.2
si:ch73-194h10.2
chr16_+_14033121 0.48 ENSDART00000135844
rusc1
RUN and SH3 domain containing 1
chr11_-_29737088 0.46 ENSDART00000159828
si:ch211-218g23.6
si:ch211-218g23.6
chr20_-_42102416 0.46 ENSDART00000186378
ENSDART00000188253
ENSDART00000186458
slc35f1
solute carrier family 35, member F1
chr4_-_45115963 0.46 ENSDART00000137248
si:dkey-51d8.6
si:dkey-51d8.6
chr22_+_7738966 0.45 ENSDART00000147073
si:ch73-44m9.5
si:ch73-44m9.5
chr22_-_8725768 0.45 ENSDART00000189873
ENSDART00000181819
si:ch73-27e22.1
si:ch73-27e22.8
si:ch73-27e22.1
si:ch73-27e22.8
chr21_+_16145980 0.44 ENSDART00000135119
qrfpr4
pyroglutamylated RFamide peptide receptor 4
chr4_+_57583139 0.41 ENSDART00000158802
il17ra1b
interleukin 17 receptor A1b
chr14_+_30795559 0.41 ENSDART00000006132
cfl1
cofilin 1
chr10_-_5847655 0.41 ENSDART00000192773
ankrd55
ankyrin repeat domain 55
chr8_+_18011522 0.40 ENSDART00000136756
ssbp3b
single stranded DNA binding protein 3b
chr3_-_39180048 0.39 ENSDART00000049720
cdk21
cyclin-dependent kinase 21
chr5_-_25723079 0.39 ENSDART00000014013
gda
guanine deaminase
chr1_-_19215336 0.37 ENSDART00000162949
ENSDART00000170680
ptprdb
protein tyrosine phosphatase, receptor type, D, b
chr10_+_35358675 0.37 ENSDART00000193263
si:dkey-259j3.5
si:dkey-259j3.5
chr23_-_1660708 0.37 ENSDART00000175138
CU693481.1

chr5_-_68074592 0.35 ENSDART00000165052
ENSDART00000018792
spag7
sperm associated antigen 7
chr1_+_33668236 0.34 ENSDART00000122316
ENSDART00000102184
arl13b
ADP-ribosylation factor-like 13b
chr2_+_53204750 0.34 ENSDART00000163644
zgc:165603
zgc:165603
chr8_-_53044089 0.33 ENSDART00000135982
nr6a1a
nuclear receptor subfamily 6, group A, member 1a
chr6_+_52877147 0.33 ENSDART00000174370
or137-8
odorant receptor, family H, subfamily 137, member 8
chr22_-_35330532 0.33 ENSDART00000172654
FO818743.1

chr14_+_36521005 0.31 ENSDART00000192286
TENM3
si:dkey-237h12.3
chr9_+_43799829 0.29 ENSDART00000186240
ube2e3
ubiquitin-conjugating enzyme E2E 3 (UBC4/5 homolog, yeast)
chr11_-_16152400 0.29 ENSDART00000123665
arpc4l
actin related protein 2/3 complex, subunit 4, like
chr6_-_40842768 0.29 ENSDART00000076160
mustn1a
musculoskeletal, embryonic nuclear protein 1a
chr8_+_28695914 0.28 ENSDART00000033386
ocstamp
osteoclast stimulatory transmembrane protein
chr11_-_2838699 0.27 ENSDART00000066189
lhfpl5a
LHFPL tetraspan subfamily member 5a
chr25_+_20715950 0.27 ENSDART00000180223
ergic2
ERGIC and golgi 2
chr9_-_41062412 0.26 ENSDART00000193879
ankar
ankyrin and armadillo repeat containing
chr23_+_16815353 0.25 ENSDART00000142789
ENSDART00000143424
zgc:100832
zgc:100832
chr15_-_35134918 0.24 ENSDART00000157196
si:ch211-272b8.7
si:ch211-272b8.7
chr22_-_20011476 0.23 ENSDART00000093312
ENSDART00000093310
celf5a
cugbp, Elav-like family member 5a
chr18_-_16924221 0.22 ENSDART00000122102
wee1
WEE1 G2 checkpoint kinase
chr12_-_41684729 0.22 ENSDART00000184461
jakmip3
Janus kinase and microtubule interacting protein 3
chr8_-_13184989 0.22 ENSDART00000135738
zgc:194990
zgc:194990
chr23_-_7674902 0.22 ENSDART00000185612
ENSDART00000180524
plagl2
pleiomorphic adenoma gene-like 2
chr20_-_9095105 0.21 ENSDART00000140792
oma1
OMA1 zinc metallopeptidase
chr1_-_31171242 0.21 ENSDART00000190294
kcnq5b
potassium voltage-gated channel, KQT-like subfamily, member 5b
chr16_-_27677930 0.20 ENSDART00000145991
tbrg4
transforming growth factor beta regulator 4
chr18_+_17827149 0.20 ENSDART00000190237
ENSDART00000189345
ZNF423
si:ch211-216l23.1
chr11_+_2506516 0.20 ENSDART00000130886
ENSDART00000189767
NABP2
si:ch73-190f16.2
chr20_-_47188966 0.19 ENSDART00000152965
si:dkeyp-104f11.9
si:dkeyp-104f11.9
chr17_-_10122204 0.18 ENSDART00000160751
BX088587.1

chr1_-_33351780 0.17 ENSDART00000178996
gyg2
glycogenin 2
chr22_-_26865181 0.17 ENSDART00000138311
hmox2a
heme oxygenase 2a
chr14_-_4556896 0.16 ENSDART00000044678
ENSDART00000192863
GABRA2
gamma-aminobutyric acid type A receptor alpha2 subunit
chr4_+_20566371 0.16 ENSDART00000127576
BX248410.1

chr1_-_17715493 0.16 ENSDART00000133027
si:dkey-256e7.8
si:dkey-256e7.8
chr8_-_50888806 0.16 ENSDART00000053750
acsl2
acyl-CoA synthetase long chain family member 2
chr18_+_7073130 0.16 ENSDART00000101216
ENSDART00000148947
si:dkey-88e18.2
si:dkey-88e18.2
chr7_-_50410524 0.15 ENSDART00000083346
hypk
huntingtin interacting protein K
chr15_+_15856178 0.15 ENSDART00000080338
dusp14
dual specificity phosphatase 14
chr8_-_25034411 0.14 ENSDART00000135973
nfyal
nuclear transcription factor Y, alpha, like
chr4_+_11458078 0.13 ENSDART00000037600
ankrd16
ankyrin repeat domain 16
chr11_+_16152316 0.12 ENSDART00000081054
tada3l
transcriptional adaptor 3 (NGG1 homolog, yeast)-like
chr12_+_30706158 0.10 ENSDART00000133869
kcnk1a
potassium channel, subfamily K, member 1a
chr23_-_37575030 0.10 ENSDART00000031875
tor1l3
torsin family 1 like 3
chr3_+_54744069 0.10 ENSDART00000134958
ENSDART00000114443
si:ch211-74m13.3
si:ch211-74m13.3
chr11_+_705727 0.09 ENSDART00000165366
timp4.2
TIMP metallopeptidase inhibitor 4, tandem duplicate 2
chr13_-_37229245 0.09 ENSDART00000140923
si:dkeyp-77c8.5
si:dkeyp-77c8.5
chr8_+_25034544 0.06 ENSDART00000123300
ngrn
neugrin, neurite outgrowth associated
chr16_+_35916371 0.06 ENSDART00000167208
sh3d21
SH3 domain containing 21
chr4_-_61691066 0.06 ENSDART00000159114
znf1129
zinc finger protein 1129
chr7_-_66868543 0.05 ENSDART00000149680
ampd3a
adenosine monophosphate deaminase 3a
chr19_+_46158078 0.05 ENSDART00000183933
ENSDART00000164055
cap2
CAP, adenylate cyclase-associated protein, 2 (yeast)
chr3_-_36701870 0.04 ENSDART00000183457
myh11b
myosin, heavy chain 11b, smooth muscle
chr15_-_47115787 0.03 ENSDART00000192601
CABZ01079081.1

Network of associatons between targets according to the STRING database.

First level regulatory network of nkx1.2la

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 2.1 GO:0006660 phosphatidylserine catabolic process(GO:0006660) monoacylglycerol metabolic process(GO:0046462) monoacylglycerol catabolic process(GO:0052651)
0.4 2.9 GO:0042983 amyloid precursor protein biosynthetic process(GO:0042983) regulation of amyloid precursor protein biosynthetic process(GO:0042984)
0.4 1.6 GO:0045669 positive regulation of osteoblast differentiation(GO:0045669)
0.3 1.0 GO:0019628 urate catabolic process(GO:0019628) urate metabolic process(GO:0046415)
0.3 1.7 GO:0021767 mammillary body development(GO:0021767)
0.2 1.2 GO:0097428 protein maturation by iron-sulfur cluster transfer(GO:0097428)
0.2 2.4 GO:0051491 positive regulation of filopodium assembly(GO:0051491)
0.2 0.6 GO:0045579 positive regulation of B cell differentiation(GO:0045579)
0.2 0.9 GO:1904105 positive regulation of convergent extension involved in gastrulation(GO:1904105)
0.2 2.9 GO:0044872 lipoprotein transport(GO:0042953) lipoprotein localization(GO:0044872)
0.2 0.8 GO:0031293 membrane protein intracellular domain proteolysis(GO:0031293)
0.1 2.0 GO:0015721 bile acid and bile salt transport(GO:0015721)
0.1 0.4 GO:0030043 actin filament fragmentation(GO:0030043)
0.1 0.8 GO:0006788 heme oxidation(GO:0006788)
0.1 0.4 GO:0006145 purine nucleobase catabolic process(GO:0006145)
0.1 0.6 GO:2001223 negative regulation of neuron migration(GO:2001223)
0.1 0.5 GO:0038093 Fc receptor signaling pathway(GO:0038093)
0.1 1.0 GO:0003352 regulation of cilium movement(GO:0003352)
0.1 0.3 GO:0097500 receptor localization to nonmotile primary cilium(GO:0097500) protein localization to ciliary membrane(GO:1903441)
0.1 1.0 GO:0031954 positive regulation of protein autophosphorylation(GO:0031954)
0.1 1.7 GO:0060325 face morphogenesis(GO:0060325)
0.1 1.5 GO:0035860 esophagus smooth muscle contraction(GO:0014846) glial cell-derived neurotrophic factor receptor signaling pathway(GO:0035860)
0.1 1.4 GO:0045162 clustering of voltage-gated sodium channels(GO:0045162)
0.1 0.8 GO:0046341 CDP-diacylglycerol biosynthetic process(GO:0016024) CDP-diacylglycerol metabolic process(GO:0046341)
0.1 1.5 GO:0048679 regulation of axon regeneration(GO:0048679) regulation of neuron projection regeneration(GO:0070570)
0.1 0.9 GO:0061484 hematopoietic stem cell homeostasis(GO:0061484)
0.1 1.9 GO:0030497 fatty acid elongation(GO:0030497)
0.1 0.6 GO:0006543 glutamate biosynthetic process(GO:0006537) glutamine catabolic process(GO:0006543)
0.1 1.6 GO:0048791 calcium ion-regulated exocytosis of neurotransmitter(GO:0048791)
0.1 0.7 GO:0060561 apoptotic process involved in morphogenesis(GO:0060561)
0.1 0.7 GO:1990748 response to superoxide(GO:0000303) response to oxygen radical(GO:0000305) removal of superoxide radicals(GO:0019430) cellular response to oxygen radical(GO:0071450) cellular response to superoxide(GO:0071451) cellular oxidant detoxification(GO:0098869) cellular detoxification(GO:1990748)
0.1 1.5 GO:0033138 positive regulation of peptidyl-serine phosphorylation(GO:0033138)
0.1 0.3 GO:0035988 chondrocyte proliferation(GO:0035988)
0.1 1.3 GO:0000028 ribosomal small subunit assembly(GO:0000028)
0.1 1.2 GO:0018149 peptide cross-linking(GO:0018149)
0.1 0.6 GO:0002031 G-protein coupled receptor internalization(GO:0002031)
0.0 1.1 GO:0045773 positive regulation of axon extension(GO:0045773)
0.0 0.5 GO:0098719 sodium ion import(GO:0097369) sodium ion import across plasma membrane(GO:0098719) sodium ion import into cell(GO:1990118)
0.0 0.9 GO:0042541 hemoglobin biosynthetic process(GO:0042541)
0.0 2.8 GO:0006096 glycolytic process(GO:0006096)
0.0 0.3 GO:0070979 protein K11-linked ubiquitination(GO:0070979)
0.0 0.2 GO:1990845 adaptive thermogenesis(GO:1990845)
0.0 0.2 GO:0044528 regulation of mitochondrial mRNA stability(GO:0044528)
0.0 2.1 GO:0007605 sensory perception of sound(GO:0007605)
0.0 0.7 GO:0045746 negative regulation of Notch signaling pathway(GO:0045746)
0.0 0.7 GO:0048665 neuron fate specification(GO:0048665)
0.0 0.1 GO:0071763 nuclear membrane organization(GO:0071763)
0.0 1.2 GO:1902668 negative regulation of axon extension involved in axon guidance(GO:0048843) negative regulation of axon guidance(GO:1902668)
0.0 0.7 GO:0043966 histone H3 acetylation(GO:0043966)
0.0 0.2 GO:0035338 long-chain fatty-acyl-CoA biosynthetic process(GO:0035338)
0.0 0.1 GO:0051045 negative regulation of membrane protein ectodomain proteolysis(GO:0051045)
0.0 0.4 GO:0003323 type B pancreatic cell development(GO:0003323)
0.0 0.3 GO:0006516 glycoprotein catabolic process(GO:0006516)
0.0 1.2 GO:0007218 neuropeptide signaling pathway(GO:0007218)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.6 GO:0042584 chromaffin granule membrane(GO:0042584)
0.3 2.9 GO:0034362 low-density lipoprotein particle(GO:0034362)
0.2 1.4 GO:0070032 synaptobrevin 2-SNAP-25-syntaxin-1a-complexin I complex(GO:0070032)
0.1 0.9 GO:0016012 sarcoglycan complex(GO:0016012)
0.1 6.3 GO:0030426 growth cone(GO:0030426)
0.0 1.0 GO:0005858 axonemal dynein complex(GO:0005858)
0.0 0.7 GO:0000124 SAGA complex(GO:0000124)
0.0 0.8 GO:0046658 anchored component of plasma membrane(GO:0046658)
0.0 0.6 GO:0001917 photoreceptor inner segment(GO:0001917)
0.0 0.6 GO:0044327 dendritic spine head(GO:0044327) phagocytic vesicle(GO:0045335)
0.0 1.3 GO:0022627 cytosolic small ribosomal subunit(GO:0022627)
0.0 1.4 GO:0034707 chloride channel complex(GO:0034707)
0.0 2.0 GO:0005795 Golgi stack(GO:0005795)
0.0 1.5 GO:0099501 synaptic vesicle membrane(GO:0030672) exocytic vesicle membrane(GO:0099501)
0.0 1.5 GO:0005581 collagen trimer(GO:0005581)
0.0 0.9 GO:0022625 cytosolic large ribosomal subunit(GO:0022625)
0.0 0.3 GO:0060170 ciliary membrane(GO:0060170)
0.0 0.1 GO:0016602 CCAAT-binding factor complex(GO:0016602)
0.0 0.3 GO:0033116 endoplasmic reticulum-Golgi intermediate compartment membrane(GO:0033116)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 1.9 GO:0018812 3-hydroxyacyl-CoA dehydratase activity(GO:0018812) 3-hydroxy-behenoyl-CoA dehydratase activity(GO:0102344) 3-hydroxy-lignoceroyl-CoA dehydratase activity(GO:0102345)
0.5 2.8 GO:0004743 pyruvate kinase activity(GO:0004743)
0.3 2.0 GO:0008508 bile acid:sodium symporter activity(GO:0008508)
0.2 1.1 GO:0008046 axon guidance receptor activity(GO:0008046)
0.2 2.4 GO:0004157 dihydropyrimidinase activity(GO:0004157)
0.2 2.1 GO:0047372 acylglycerol lipase activity(GO:0047372)
0.1 1.3 GO:0004731 purine-nucleoside phosphorylase activity(GO:0004731)
0.1 0.8 GO:0004392 heme oxygenase (decyclizing) activity(GO:0004392)
0.1 1.0 GO:0005161 platelet-derived growth factor receptor binding(GO:0005161)
0.1 0.8 GO:0004366 glycerol-3-phosphate O-acyltransferase activity(GO:0004366)
0.1 0.7 GO:0008379 thioredoxin peroxidase activity(GO:0008379)
0.1 1.5 GO:0008449 N-acetylglucosamine-6-sulfatase activity(GO:0008449)
0.1 2.9 GO:0017075 syntaxin-1 binding(GO:0017075)
0.1 0.6 GO:0004359 glutaminase activity(GO:0004359)
0.1 0.9 GO:0005221 intracellular cyclic nucleotide activated cation channel activity(GO:0005221) intracellular cAMP activated cation channel activity(GO:0005222) intracellular cGMP activated cation channel activity(GO:0005223) cyclic nucleotide-gated ion channel activity(GO:0043855)
0.1 1.7 GO:0005112 Notch binding(GO:0005112)
0.1 1.2 GO:0003810 protein-glutamine gamma-glutamyltransferase activity(GO:0003810)
0.1 0.8 GO:0004169 dolichyl-phosphate-mannose-protein mannosyltransferase activity(GO:0004169)
0.1 1.3 GO:0043236 laminin binding(GO:0043236)
0.1 1.2 GO:0031492 nucleosomal DNA binding(GO:0031492)
0.0 0.5 GO:0015386 monovalent cation:proton antiporter activity(GO:0005451) sodium:proton antiporter activity(GO:0015385) potassium:proton antiporter activity(GO:0015386)
0.0 0.8 GO:0015026 coreceptor activity(GO:0015026)
0.0 1.6 GO:0001786 phosphatidylserine binding(GO:0001786)
0.0 0.4 GO:0030368 interleukin-17 receptor activity(GO:0030368)
0.0 0.4 GO:0008353 RNA polymerase II carboxy-terminal domain kinase activity(GO:0008353)
0.0 1.6 GO:0008188 neuropeptide receptor activity(GO:0008188)
0.0 0.6 GO:0031267 small GTPase binding(GO:0031267)
0.0 0.7 GO:0005104 fibroblast growth factor receptor binding(GO:0005104)
0.0 1.2 GO:0051539 4 iron, 4 sulfur cluster binding(GO:0051539)
0.0 1.0 GO:0016831 carboxy-lyase activity(GO:0016831)
0.0 0.8 GO:0019957 chemokine binding(GO:0019956) C-C chemokine binding(GO:0019957)
0.0 1.2 GO:0030215 semaphorin receptor binding(GO:0030215)
0.0 2.9 GO:0005179 hormone activity(GO:0005179)
0.0 0.0 GO:0008179 adenylate cyclase binding(GO:0008179)
0.0 0.2 GO:0047676 arachidonate-CoA ligase activity(GO:0047676)
0.0 1.4 GO:0005254 chloride channel activity(GO:0005254)
0.0 0.7 GO:0004402 histone acetyltransferase activity(GO:0004402)
0.0 0.5 GO:0008020 G-protein coupled photoreceptor activity(GO:0008020)
0.0 0.8 GO:0004715 non-membrane spanning protein tyrosine kinase activity(GO:0004715)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.4 SA FAS SIGNALING The TNF-type receptor Fas induces apoptosis on ligand binding.
0.0 1.3 ST WNT BETA CATENIN PATHWAY Wnt/beta-catenin Pathway
0.0 1.5 PID CDC42 REG PATHWAY Regulation of CDC42 activity
0.0 0.6 PID NFKAPPAB ATYPICAL PATHWAY Atypical NF-kappaB pathway
0.0 0.2 SA G2 AND M PHASES Cdc25 activates the cdc2/cyclin B complex to induce the G2/M transition.
0.0 0.8 PID BMP PATHWAY BMP receptor signaling
0.0 0.7 PID FGF PATHWAY FGF signaling pathway
0.0 0.5 PID MAPK TRK PATHWAY Trk receptor signaling mediated by the MAPK pathway
0.0 0.9 PID CMYB PATHWAY C-MYB transcription factor network

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 2.6 REACTOME RECYCLING OF BILE ACIDS AND SALTS Genes involved in Recycling of bile acids and salts
0.3 2.9 REACTOME CHYLOMICRON MEDIATED LIPID TRANSPORT Genes involved in Chylomicron-mediated lipid transport
0.2 2.4 REACTOME CRMPS IN SEMA3A SIGNALING Genes involved in CRMPs in Sema3A signaling
0.2 2.4 REACTOME SYNTHESIS OF PE Genes involved in Synthesis of PE
0.2 0.8 REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES Genes involved in Chemokine receptors bind chemokines
0.1 0.7 REACTOME FGFR4 LIGAND BINDING AND ACTIVATION Genes involved in FGFR4 ligand binding and activation
0.1 0.4 REACTOME SEMA3A PAK DEPENDENT AXON REPULSION Genes involved in Sema3A PAK dependent Axon repulsion
0.1 0.4 REACTOME PURINE CATABOLISM Genes involved in Purine catabolism
0.0 0.6 REACTOME REGULATION OF SIGNALING BY CBL Genes involved in Regulation of signaling by CBL
0.0 1.3 REACTOME FORMATION OF THE TERNARY COMPLEX AND SUBSEQUENTLY THE 43S COMPLEX Genes involved in Formation of the ternary complex, and subsequently, the 43S complex
0.0 0.8 REACTOME NETRIN1 SIGNALING Genes involved in Netrin-1 signaling
0.0 0.7 REACTOME SIGNALING BY ROBO RECEPTOR Genes involved in Signaling by Robo receptor
0.0 0.2 REACTOME G2 M DNA DAMAGE CHECKPOINT Genes involved in G2/M DNA damage checkpoint
0.0 0.2 REACTOME GLYCOGEN BREAKDOWN GLYCOGENOLYSIS Genes involved in Glycogen breakdown (glycogenolysis)
0.0 0.9 REACTOME PEPTIDE CHAIN ELONGATION Genes involved in Peptide chain elongation
0.0 0.2 REACTOME GABA A RECEPTOR ACTIVATION Genes involved in GABA A receptor activation