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PRJNA195909:zebrafish embryo and larva development

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Results for nfe2l1b+nfe2l2b

Z-value: 0.61

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Transcription factors associated with nfe2l1b+nfe2l2b

Gene Symbol Gene ID Gene Info
ENSDARG00000076533 nuclear factor, erythroid 2-like 1b
ENSDARG00000089697 nuclear factor, erythroid 2-like 2b
ENSDARG00000114820 nuclear factor, erythroid 2-like 1b

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
nfe2l1bdr11_v1_chr12_+_28854410_288544100.863.3e-03Click!
nfe2l2bdr11_v1_chr6_-_10902916_10902916-0.157.1e-01Click!

Activity profile of nfe2l1b+nfe2l2b motif

Sorted Z-values of nfe2l1b+nfe2l2b motif

Promoter Log-likelihood Transcript Gene Gene Info
chr3_-_55139127 1.00 ENSDART00000115324
hemoglobin, alpha embryonic 1.3
chr3_-_55128258 0.82 ENSDART00000101734
hemoglobin, alpha embryonic 1
chr1_-_59252973 0.77 ENSDART00000167061
si:ch1073-286c18.5
chr6_+_584632 0.76 ENSDART00000151150
zgc:92360
chr7_+_26709251 0.74 ENSDART00000149426
ENSDART00000010323
CD82 molecule a
chr11_+_30306606 0.71 ENSDART00000128276
ENSDART00000190222
UDP glucuronosyltransferase 1 family, polypeptide B4
chr14_+_21107032 0.71 ENSDART00000138319
ENSDART00000139103
ENSDART00000184735
aldolase b, fructose-bisphosphate
chr5_+_37087583 0.71 ENSDART00000049900
transgelin 2
chr20_+_26538137 0.69 ENSDART00000045397
syntaxin 11b, tandem duplicate 1
chr7_+_38750871 0.66 ENSDART00000114238
ENSDART00000052325
ENSDART00000137001
coagulation factor II (thrombin)
chr2_+_27010439 0.65 ENSDART00000030547
cadherin 7a
chr3_+_31621774 0.65 ENSDART00000076636
frizzled class receptor 2
chr24_+_9744012 0.61 ENSDART00000129656
transmembrane protein 108
chr11_+_30310170 0.60 ENSDART00000127797
UDP glucuronosyltransferase 1 family, polypeptide B3
chr4_+_306036 0.59 ENSDART00000103659
mesogenin 1
chr18_-_46010 0.58 ENSDART00000052641
glycine amidinotransferase (L-arginine:glycine amidinotransferase)
chr15_-_18138607 0.58 ENSDART00000176690

chr1_-_38756870 0.54 ENSDART00000130324
ENSDART00000148404
glycoprotein M6Ab
chr7_-_41627956 0.53 ENSDART00000083929
plexin domain containing 2
chr16_+_42829735 0.50 ENSDART00000014956
polymerase (RNA) III (DNA directed) polypeptide G like b
chr21_+_18353703 0.50 ENSDART00000181396
ENSDART00000166359
si:ch73-287m6.1
chr8_-_554540 0.50 ENSDART00000163934
Danio rerio uncharacterized LOC100329294 (LOC100329294), mRNA.
chr3_+_46635527 0.48 ENSDART00000153971
si:dkey-248g21.1
chr15_+_36966369 0.48 ENSDART00000163622
kirre like nephrin family adhesion molecule 3, like
chr5_-_63509581 0.47 ENSDART00000097325
complement component 5
chr19_-_4010263 0.47 ENSDART00000159605
ENSDART00000165541
MAP7 domain containing 1b
chr16_+_26777473 0.47 ENSDART00000188870
cadherin 17, LI cadherin (liver-intestine)
chr12_+_20336070 0.47 ENSDART00000066385
zgc:163057
chr12_+_6041575 0.46 ENSDART00000091868
glucose-6-phosphatase a, catalytic subunit, tandem duplicate 2
chr8_-_50981175 0.46 ENSDART00000004065
zgc:91909
chr14_+_18785727 0.45 ENSDART00000184452
si:ch211-111e20.1
chr10_-_22918214 0.45 ENSDART00000163908
ribonuclease, RNase K b
chr3_+_30500968 0.44 ENSDART00000103447
si:dkey-13n23.3
chr6_-_49526510 0.43 ENSDART00000128025
ribosomal protein S26, like
chr1_-_52494122 0.43 ENSDART00000131407
aspartoacylase (aminocyclase) 3, tandem duplicate 2
chr4_+_5249494 0.43 ENSDART00000150391
si:ch211-214j24.14
chr5_+_53482597 0.43 ENSDART00000180333

chr20_-_35246150 0.43 ENSDART00000090549
frizzled class receptor 3a
chr9_-_23152092 0.42 ENSDART00000180155
ENSDART00000186935
LY6/PLAUR domain containing 6B
chr14_+_34547554 0.42 ENSDART00000074819
gamma-aminobutyric acid (GABA) A receptor, pi
chr24_-_17029374 0.42 ENSDART00000039267
prostaglandin D2 synthase b, tandem duplicate 1
chr21_-_26495700 0.41 ENSDART00000109379
CD248 molecule, endosialin b
chr13_-_37127970 0.41 ENSDART00000135510
spectrin repeat containing, nuclear envelope 2b
chr16_-_29714540 0.41 ENSDART00000067854
tumor necrosis factor, alpha-induced protein 8-like 2b
chr7_-_7398350 0.41 ENSDART00000012637
zgc:101810
chr4_+_3358383 0.40 ENSDART00000075320
nicotinamide phosphoribosyltransferase a
chr14_+_3287740 0.39 ENSDART00000186290
caudal type homeobox 1a
chr8_-_32805214 0.38 ENSDART00000131597
zgc:194839
chr20_-_54259780 0.38 ENSDART00000172631
FK506 binding protein 3
chr10_+_25369254 0.38 ENSDART00000164375
BTB and CNC homology 1, basic leucine zipper transcription factor 1 b
chr6_-_24301324 0.37 ENSDART00000171401

chr2_-_30055432 0.37 ENSDART00000056747
sonic hedgehog b
chr18_-_28938912 0.37 ENSDART00000136201
si:ch211-174j14.2
chr9_+_19095023 0.36 ENSDART00000110457
ENSDART00000099426
ENSDART00000137087
cytokine receptor family member b1
chr22_+_10201826 0.36 ENSDART00000006513
ENSDART00000132641
pyruvate dehydrogenase E1 beta subunit
chr22_+_3156386 0.35 ENSDART00000161212
ribosomal protein L36
chr1_+_26411496 0.35 ENSDART00000112263
Rho guanine nucleotide exchange factor (GEF) 38
chr3_+_33300522 0.34 ENSDART00000114023
heat shock protein, alpha-crystallin-related, 9
chr15_-_15469079 0.33 ENSDART00000132637
ENSDART00000004220
RAB34, member RAS oncogene family a
chr16_-_51288178 0.33 ENSDART00000079864
zgc:173729
chr24_-_17023392 0.33 ENSDART00000106058
prostaglandin D2 synthase b, tandem duplicate 2
chr3_-_18744511 0.32 ENSDART00000145539
zgc:113333
chr4_+_57881965 0.32 ENSDART00000162234
si:dkeyp-44b5.4
chr3_-_27647845 0.32 ENSDART00000151625
si:ch211-157c3.4
chr24_-_32408404 0.32 ENSDART00000144157
si:ch211-56a11.2
chr17_-_24684687 0.32 ENSDART00000105457
MORN repeat containing 2
chr13_-_4223955 0.32 ENSDART00000113060
2'-deoxynucleoside 5'-phosphate N-hydrolase 1
chr13_-_49819027 0.32 ENSDART00000067824
beta-1,3-N-acetylgalactosaminyltransferase 2
chr23_-_19827411 0.31 ENSDART00000187964
HAUS augmin-like complex, subunit 7
chr1_-_59141715 0.31 ENSDART00000164941
ENSDART00000138870
si:ch1073-110a20.1
chr7_+_6969909 0.31 ENSDART00000189886
actinin alpha 3b
chr20_-_40720458 0.31 ENSDART00000153151
ENSDART00000061261
ENSDART00000138569
connexin 43
chr24_-_24146875 0.30 ENSDART00000173052
MAP7 domain containing 2b
chr7_-_5316901 0.30 ENSDART00000181505
ENSDART00000124367
si:cabz01074946.1
chr2_-_30659222 0.30 ENSDART00000145405
catenin (cadherin-associated protein), delta 2b
chr22_-_26865361 0.29 ENSDART00000182504
heme oxygenase 2a
chr17_-_31659670 0.29 ENSDART00000030448
visual system homeobox 2
chr3_+_39099716 0.29 ENSDART00000083388
transmembrane protein 98
chr6_-_46589726 0.29 ENSDART00000084334
prostaglandin I2 (prostacyclin) synthase
chr8_-_2506327 0.29 ENSDART00000101125
ENSDART00000125124
ribosomal protein L6
chr10_+_42733210 0.29 ENSDART00000189832

chr4_+_25220674 0.29 ENSDART00000066934
inter-alpha-trypsin inhibitor heavy chain family, member 5
chr8_+_24745041 0.29 ENSDART00000148872
solute carrier family 16, member 4
chr7_+_5530154 0.29 ENSDART00000181610
si:dkeyp-67a8.4
chr4_-_30174588 0.29 ENSDART00000135420
ENSDART00000004188
si:dkey-265e15.5
chr4_-_60790123 0.28 ENSDART00000137702
si:dkey-254e13.6
chr6_-_55297274 0.28 ENSDART00000184283
ubiquitin-conjugating enzyme E2C
chr3_+_22442445 0.27 ENSDART00000190921
WNK lysine deficient protein kinase 4b
chr12_+_16281312 0.27 ENSDART00000152500
protein phosphatase 1, regulatory subunit 3Cb
chr16_-_29557338 0.27 ENSDART00000058888
HORMA domain containing 1
chr16_+_46807214 0.27 ENSDART00000185524

chr21_-_5881344 0.27 ENSDART00000009241
ribosomal protein L35
chr5_-_67471375 0.27 ENSDART00000147009
si:dkey-251i10.2
chr5_-_9073433 0.27 ENSDART00000099891
ATP synthase membrane subunit eb
chr11_+_11974708 0.27 ENSDART00000125060
zgc:64002
chr4_-_52165969 0.26 ENSDART00000171130
si:dkeyp-44b5.4
chr10_-_29903165 0.26 ENSDART00000078800
lens intrinsic membrane protein 2.1
chr14_-_17588345 0.26 ENSDART00000143486
selenoprotein T, 2
chr14_-_970853 0.26 ENSDART00000130801
acyl-CoA synthetase long chain family member 1b
chr14_-_9281232 0.26 ENSDART00000054693
ankyrin repeat and SOCS box-containing 12b
chr3_+_30501135 0.25 ENSDART00000165869
si:dkey-13n23.3
chr4_-_56898328 0.25 ENSDART00000169189
si:dkey-269o24.6
chr13_+_22280983 0.25 ENSDART00000173258
ENSDART00000173379
ubiquitin specific peptidase 54a
chr8_+_25615781 0.25 ENSDART00000062385
solute carrier family 38, member 5a
chr19_-_32928470 0.24 ENSDART00000141404
ENSDART00000050750
ribonucleotide reductase M2 b
chr12_+_22823219 0.24 ENSDART00000153199
ENSDART00000192571
actin filament associated protein 1
chr8_-_27849770 0.24 ENSDART00000190196
ENSDART00000181244
CTTNBP2 N-terminal like b
chr23_+_4890693 0.24 ENSDART00000023537
troponin C type 1a (slow)
chr2_-_38035235 0.24 ENSDART00000075904
cerebellin 5
chr12_+_30586599 0.24 ENSDART00000124920
ENSDART00000126984
nebulin-related anchoring protein
chr19_-_19339285 0.24 ENSDART00000158413
ENSDART00000170479
chondroitin sulfate proteoglycan 5b
chr24_+_38301080 0.24 ENSDART00000105672
myosin binding protein C, fast type b
chr16_-_22192006 0.23 ENSDART00000163338
interleukin 6 receptor
chr3_-_32603191 0.23 ENSDART00000150997
si:ch73-248e21.7
chr20_+_10727022 0.23 ENSDART00000104185
si:ch211-182e10.4
chr11_+_37216668 0.23 ENSDART00000173076
zgc:112265
chr25_+_469855 0.23 ENSDART00000104717
ribosomal L24 domain containing 1
chr22_+_2860260 0.23 ENSDART00000106221
si:dkey-20i20.2
chr2_+_1486822 0.23 ENSDART00000132500
complement component 8, alpha polypeptide
chr18_+_808911 0.22 ENSDART00000172518
cytochrome c oxidase subunit Vab
chr4_+_39766931 0.22 ENSDART00000138663
si:dkeyp-85d8.1
chr8_-_18535822 0.22 ENSDART00000100558
nexilin (F actin binding protein)
chr6_+_120181 0.22 ENSDART00000151209
ENSDART00000185930
cyclin-dependent kinase inhibitor 2D (p19, inhibits CDK4)
chr25_-_16554757 0.22 ENSDART00000154480
si:ch211-266k8.6
chr8_+_22289320 0.22 ENSDART00000075126
UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 7, like
chr4_+_37952218 0.22 ENSDART00000186865
si:dkeyp-82b4.2
chr1_-_59104145 0.22 ENSDART00000132495
ENSDART00000152457
si:zfos-2330d3.1
si:zfos-2330d3.7
chr24_-_39186185 0.22 ENSDART00000123019
ENSDART00000191114
nucleotide binding protein 2 (MinD homolog, E. coli)
chr18_-_49116382 0.22 ENSDART00000174157

chr1_-_45157243 0.22 ENSDART00000131882
mucin, multiple PTS and SEA group, member 1
chr3_-_34084387 0.22 ENSDART00000155365
immunoglobulin heavy variable 4-3
chr17_-_28707898 0.22 ENSDART00000135752
ENSDART00000061853
adaptor-related protein complex 4, sigma 1 subunit
chr15_+_5973909 0.22 ENSDART00000126886
ENSDART00000189618
immunoglobulin superfamily, member 5b
chr11_+_44622472 0.22 ENSDART00000159068
ENSDART00000166323
ENSDART00000187753
RNA binding motif protein 34
chr3_+_36284986 0.22 ENSDART00000059533
WD repeat domain, phosphoinositide interacting 1
chr15_-_31514818 0.22 ENSDART00000153978
high mobility group box 1b
chr8_+_32406885 0.21 ENSDART00000167600
epithelial mitogen homolog (mouse)
chr11_+_24900123 0.21 ENSDART00000044987
ENSDART00000148023
translocase of inner mitochondrial membrane 17 homolog A (yeast)
chr2_-_30135446 0.21 ENSDART00000141906
transient receptor potential cation channel, subfamily A, member 1a
chr7_-_19600181 0.21 ENSDART00000100757
oxidase (cytochrome c) assembly 1-like
chr16_-_51407525 0.21 ENSDART00000090530
si:ch211-107n13.1
chr4_-_20115570 0.21 ENSDART00000134528
si:dkey-159a18.1
chr6_+_40775800 0.21 ENSDART00000085090
si:ch211-157b11.8
chr19_-_40855106 0.20 ENSDART00000087421
tissue factor pathway inhibitor 2
chr23_+_34001803 0.20 ENSDART00000128759
si:ch211-207e14.4
chr1_+_47486104 0.20 ENSDART00000114746
leucine rich repeat containing 58a
chr15_+_638457 0.20 ENSDART00000157162
zinc finger protein 1013
chr6_+_6797520 0.20 ENSDART00000150967
si:ch211-85n16.3
chr4_+_31330731 0.20 ENSDART00000165918
si:rp71-5o12.3
chr16_-_28856112 0.19 ENSDART00000078543
synaptotagmin XIb
chr12_+_7445595 0.19 ENSDART00000103536
ENSDART00000152524
phytanoyl-CoA 2-hydroxylase interacting protein-like b
chr7_+_49681040 0.19 ENSDART00000176372
ENSDART00000192172
Ras association (RalGDS/AF-6) domain family (N-terminal) member 7b
chr24_-_26485098 0.19 ENSDART00000135496
ENSDART00000009609
ENSDART00000133782
ENSDART00000141029
ENSDART00000113739
eukaryotic translation initiation factor 5A
chr12_+_4036409 0.19 ENSDART00000106650
zgc:123217
chr4_-_9592402 0.19 ENSDART00000114060
cerebral dopamine neurotrophic factor
chr14_-_24332786 0.19 ENSDART00000173164
family with sequence similarity 13, member B
chr3_+_22375596 0.18 ENSDART00000188243
ENSDART00000181506
Rho GTPase activating protein 27, like
chr3_-_7656059 0.18 ENSDART00000170917
JunB proto-oncogene, AP-1 transcription factor subunit b
chr8_-_7851590 0.18 ENSDART00000160692
zgc:113363
chr10_-_8282815 0.18 ENSDART00000181828
phospholipid phosphatase 1a
chr14_+_24241241 0.18 ENSDART00000022377
NK2 homeobox 5
chr9_-_41062412 0.18 ENSDART00000193879
ankyrin and armadillo repeat containing
chr8_+_27807974 0.18 ENSDART00000078509
capping protein (actin filament) muscle Z-line, alpha 1b
chr14_+_9462726 0.18 ENSDART00000063559
RELT-like 2
chr24_-_1341543 0.18 ENSDART00000169341
neuropilin 1a
chr19_-_26823647 0.18 ENSDART00000002464
neuraminidase 1
chr9_-_4506819 0.18 ENSDART00000113975
potassium inwardly-rectifying channel, subfamily J, member 3a
chr7_+_5529967 0.18 ENSDART00000142709
si:dkeyp-67a8.4
chr21_-_30408775 0.18 ENSDART00000101037
NHP2 ribonucleoprotein homolog (yeast)
chr6_+_13201358 0.18 ENSDART00000190290

chr22_-_32392252 0.18 ENSDART00000148681
ENSDART00000137945
poly(rC) binding protein 4
chr7_-_29571615 0.18 ENSDART00000019140
RAR-related orphan receptor A, paralog b
chr7_-_28658143 0.18 ENSDART00000173556
adhesion G protein-coupled receptor G1
chr9_+_54984537 0.18 ENSDART00000029528
motile sperm domain containing 2
chr4_-_17805128 0.18 ENSDART00000128988
Spi-2 proto-oncogene
chr6_-_35446110 0.17 ENSDART00000058773
regulator of G protein signaling 16
chr13_+_4368504 0.17 ENSDART00000108935
SFT2 domain containing 1
chr18_+_2222447 0.17 ENSDART00000185927
PIGB opposite strand 1
chr6_-_13783604 0.17 ENSDART00000149536
ENSDART00000041269
ENSDART00000150102
crystallin, beta A2a
chr9_+_27411502 0.17 ENSDART00000143994
si:dkey-193n17.9
chr3_-_39171968 0.17 ENSDART00000154494
si:dkeyp-57f11.2
chr17_+_27456804 0.17 ENSDART00000017756
ENSDART00000181461
ENSDART00000180178
cathepsin L.1
chr11_+_37275448 0.17 ENSDART00000161423
cysteine-rich with EGF-like domains 1a
chr11_-_16093018 0.17 ENSDART00000139309
ENSDART00000139819
si:dkey-205k8.5
chr11_-_22372072 0.17 ENSDART00000065996
transmembrane protein 183A
chr10_-_41664427 0.17 ENSDART00000150213
gamma-glutamyltransferase 1b
chr8_-_10932206 0.16 ENSDART00000124313
nuclear receptor subfamily 1, group H, member 5
chr11_+_41936435 0.16 ENSDART00000173103
aldehyde dehydrogenase 4 family, member A1
chr7_+_60111581 0.16 ENSDART00000087093
heat shock protein 12B
chr4_+_33373100 0.16 ENSDART00000150417
zinc finger protein 1090
chr6_-_10835849 0.16 ENSDART00000005903
ENSDART00000135065
ATP synthase membrane subunit c locus 3b
chr23_-_38054 0.16 ENSDART00000170393

chr12_+_28854963 0.16 ENSDART00000153227
nuclear factor, erythroid 2-like 1b
chr4_-_55641422 0.16 ENSDART00000165178
zinc finger protein 1074
chr17_-_51938663 0.16 ENSDART00000179784
ergosterol biosynthesis 28 homolog
chr12_-_3962372 0.16 ENSDART00000016791
eukaryotic translation initiation factor 3, subunit C
chr10_+_21758811 0.16 ENSDART00000188827
protocadherin 1 gamma 11
chr21_-_45086170 0.16 ENSDART00000188963
Rap guanine nucleotide exchange factor (GEF) 6
chr15_-_4094888 0.16 ENSDART00000166307
si:dkey-83h2.3
chr7_+_49654588 0.16 ENSDART00000025451
ENSDART00000141934
Ras association (RalGDS/AF-6) domain family (N-terminal) member 7b

Network of associatons between targets according to the STRING database.

First level regulatory network of nfe2l1b+nfe2l2b

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.6 GO:0061341 non-canonical Wnt signaling pathway involved in heart development(GO:0061341)
0.2 0.6 GO:0048341 paraxial mesoderm morphogenesis(GO:0048340) paraxial mesoderm formation(GO:0048341)
0.2 0.6 GO:0006601 creatine metabolic process(GO:0006600) creatine biosynthetic process(GO:0006601)
0.1 0.7 GO:0006953 acute-phase response(GO:0006953)
0.1 0.3 GO:0009162 deoxyribonucleoside monophosphate metabolic process(GO:0009162)
0.1 0.6 GO:0097106 postsynaptic density organization(GO:0097106)
0.1 0.2 GO:1902626 assembly of large subunit precursor of preribosome(GO:1902626)
0.1 1.5 GO:0015671 oxygen transport(GO:0015671)
0.1 0.3 GO:0033313 meiotic cell cycle checkpoint(GO:0033313)
0.1 0.2 GO:1902024 L-histidine transmembrane transport(GO:0089709) L-histidine transport(GO:1902024)
0.1 0.4 GO:0060956 cardiac endothelial cell differentiation(GO:0003348) endocardial cell differentiation(GO:0060956)
0.1 0.2 GO:1903779 regulation of cardiac conduction(GO:1903779)
0.1 0.2 GO:1900745 positive regulation of p38MAPK cascade(GO:1900745)
0.1 0.4 GO:0006086 acetyl-CoA biosynthetic process from pyruvate(GO:0006086)
0.1 0.2 GO:0031120 snRNA pseudouridine synthesis(GO:0031120)
0.1 0.2 GO:0098908 regulation of neuronal action potential(GO:0098908)
0.1 0.3 GO:0070294 renal sodium ion transport(GO:0003096) renal sodium ion absorption(GO:0070294)
0.1 0.2 GO:0050960 thermoception(GO:0050955) detection of temperature stimulus involved in thermoception(GO:0050960) detection of temperature stimulus involved in sensory perception(GO:0050961)
0.0 0.3 GO:0006788 heme oxidation(GO:0006788)
0.0 0.2 GO:0032978 protein insertion into membrane from inner side(GO:0032978) protein insertion into mitochondrial membrane from inner side(GO:0032979) protein insertion into mitochondrial membrane(GO:0051204)
0.0 0.3 GO:0090385 phagosome-lysosome fusion(GO:0090385)
0.0 0.3 GO:0048739 cardiac muscle fiber development(GO:0048739)
0.0 0.1 GO:0042662 ventricular compact myocardium morphogenesis(GO:0003223) negative regulation of mesodermal cell fate specification(GO:0042662)
0.0 0.2 GO:0071691 cardiac muscle thin filament assembly(GO:0071691)
0.0 0.1 GO:0043455 regulation of secondary metabolic process(GO:0043455)
0.0 0.2 GO:0060055 larval development(GO:0002164) larval heart development(GO:0007508) angiogenesis involved in wound healing(GO:0060055)
0.0 0.2 GO:0048025 negative regulation of RNA splicing(GO:0033119) negative regulation of mRNA splicing, via spliceosome(GO:0048025)
0.0 0.5 GO:0001867 complement activation, lectin pathway(GO:0001867)
0.0 0.4 GO:0021754 facial nucleus development(GO:0021754)
0.0 0.1 GO:0019418 sulfide oxidation(GO:0019418) sulfide oxidation, using sulfide:quinone oxidoreductase(GO:0070221)
0.0 0.2 GO:0010133 proline catabolic process to glutamate(GO:0010133)
0.0 0.7 GO:0030388 fructose 1,6-bisphosphate metabolic process(GO:0030388)
0.0 0.3 GO:0045741 positive regulation of epidermal growth factor-activated receptor activity(GO:0045741) positive regulation of receptor activity(GO:2000273)
0.0 0.1 GO:0031179 peptide modification(GO:0031179)
0.0 0.2 GO:0070445 regulation of oligodendrocyte progenitor proliferation(GO:0070445)
0.0 0.5 GO:0051489 regulation of filopodium assembly(GO:0051489)
0.0 0.1 GO:0006531 aspartate metabolic process(GO:0006531)
0.0 0.2 GO:0009263 deoxyribonucleotide biosynthetic process(GO:0009263)
0.0 0.2 GO:0045905 positive regulation of translational elongation(GO:0045901) positive regulation of translational termination(GO:0045905)
0.0 0.7 GO:0060034 notochord cell differentiation(GO:0060034)
0.0 0.1 GO:0009202 deoxyribonucleoside triphosphate biosynthetic process(GO:0009202)
0.0 0.1 GO:0070920 regulation of production of small RNA involved in gene silencing by RNA(GO:0070920) regulation of production of miRNAs involved in gene silencing by miRNA(GO:1903798)
0.0 0.1 GO:0042787 protein ubiquitination involved in ubiquitin-dependent protein catabolic process(GO:0042787) regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process(GO:2000058)
0.0 0.5 GO:0039022 pronephric duct development(GO:0039022)
0.0 0.2 GO:0099550 trans-synaptic signalling, modulating synaptic transmission(GO:0099550)
0.0 0.1 GO:0003322 pancreatic A cell development(GO:0003322)
0.0 0.5 GO:0007274 neuromuscular synaptic transmission(GO:0007274)
0.0 0.1 GO:0050995 negative regulation of lipid catabolic process(GO:0050995)
0.0 0.1 GO:0015990 energy coupled proton transmembrane transport, against electrochemical gradient(GO:0015988) electron transport coupled proton transport(GO:0015990)
0.0 0.1 GO:0044033 viral genome replication(GO:0019079) negative stranded viral RNA replication(GO:0039689) viral RNA genome replication(GO:0039694) RNA replication(GO:0039703) multi-organism metabolic process(GO:0044033) multi-organism biosynthetic process(GO:0044034)
0.0 0.7 GO:0031629 synaptic vesicle fusion to presynaptic active zone membrane(GO:0031629) vesicle fusion to plasma membrane(GO:0099500)
0.0 0.2 GO:0031295 lymphocyte costimulation(GO:0031294) T cell costimulation(GO:0031295)
0.0 0.3 GO:0001516 prostaglandin biosynthetic process(GO:0001516) prostanoid biosynthetic process(GO:0046457)
0.0 0.1 GO:0006295 nucleotide-excision repair, DNA incision, 3'-to lesion(GO:0006295)
0.0 0.2 GO:0071459 protein localization to kinetochore(GO:0034501) protein localization to chromosome, centromeric region(GO:0071459)
0.0 0.1 GO:0036445 neuronal stem cell division(GO:0036445) somatic stem cell division(GO:0048103)
0.0 0.2 GO:0034497 protein localization to pre-autophagosomal structure(GO:0034497)
0.0 0.4 GO:0015986 energy coupled proton transport, down electrochemical gradient(GO:0015985) ATP synthesis coupled proton transport(GO:0015986)
0.0 0.2 GO:0006123 mitochondrial electron transport, cytochrome c to oxygen(GO:0006123)
0.0 0.2 GO:0030311 poly-N-acetyllactosamine metabolic process(GO:0030309) poly-N-acetyllactosamine biosynthetic process(GO:0030311)
0.0 0.3 GO:0061074 regulation of neural retina development(GO:0061074)
0.0 0.3 GO:0030212 hyaluronan metabolic process(GO:0030212)
0.0 0.2 GO:0009313 oligosaccharide catabolic process(GO:0009313)
0.0 0.1 GO:0070863 positive regulation of protein exit from endoplasmic reticulum(GO:0070863) protein localization to endoplasmic reticulum exit site(GO:0070973)
0.0 0.3 GO:0000463 maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000463)
0.0 0.1 GO:0048635 negative regulation of muscle organ development(GO:0048635)
0.0 0.2 GO:2000249 regulation of actin cytoskeleton reorganization(GO:2000249)
0.0 0.3 GO:0060997 dendritic spine morphogenesis(GO:0060997)
0.0 0.3 GO:0000027 ribosomal large subunit assembly(GO:0000027)
0.0 0.1 GO:0071340 skeletal muscle acetylcholine-gated channel clustering(GO:0071340)
0.0 0.2 GO:0014823 response to activity(GO:0014823)
0.0 0.1 GO:0032790 ribosome disassembly(GO:0032790)
0.0 0.1 GO:0031444 slow-twitch skeletal muscle fiber contraction(GO:0031444)
0.0 0.3 GO:0010962 regulation of glycogen biosynthetic process(GO:0005979) regulation of glucan biosynthetic process(GO:0010962) regulation of polysaccharide biosynthetic process(GO:0032885)
0.0 0.2 GO:0030150 protein import into mitochondrial matrix(GO:0030150)
0.0 0.0 GO:0034969 histone arginine methylation(GO:0034969)
0.0 0.2 GO:0048769 sarcomerogenesis(GO:0048769)
0.0 0.1 GO:1902975 cell cycle DNA replication initiation(GO:1902292) nuclear cell cycle DNA replication initiation(GO:1902315) mitotic DNA replication initiation(GO:1902975)
0.0 0.1 GO:1903306 negative regulation of calcium ion-dependent exocytosis(GO:0045955) negative regulation of regulated secretory pathway(GO:1903306)
0.0 0.1 GO:0018120 peptidyl-arginine ADP-ribosylation(GO:0018120)
0.0 0.1 GO:0071850 mitotic cell cycle arrest(GO:0071850)
0.0 0.1 GO:0048532 anatomical structure arrangement(GO:0048532)
0.0 0.3 GO:0035338 long-chain fatty-acyl-CoA biosynthetic process(GO:0035338)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.5 GO:0031838 haptoglobin-hemoglobin complex(GO:0031838)
0.1 0.4 GO:0005967 mitochondrial pyruvate dehydrogenase complex(GO:0005967)
0.0 0.2 GO:0008290 F-actin capping protein complex(GO:0008290)
0.0 0.5 GO:0044295 axonal growth cone(GO:0044295)
0.0 0.2 GO:0031429 box H/ACA snoRNP complex(GO:0031429) box H/ACA RNP complex(GO:0072588)
0.0 0.3 GO:0070652 HAUS complex(GO:0070652)
0.0 0.2 GO:1990130 Iml1 complex(GO:1990130)
0.0 0.7 GO:0048787 presynaptic active zone membrane(GO:0048787)
0.0 0.4 GO:0000276 mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)(GO:0000276)
0.0 0.2 GO:0034045 pre-autophagosomal structure membrane(GO:0034045)
0.0 0.1 GO:0008537 proteasome activator complex(GO:0008537)
0.0 0.5 GO:0005666 DNA-directed RNA polymerase III complex(GO:0005666)
0.0 0.4 GO:0005885 Arp2/3 protein complex(GO:0005885)
0.0 1.1 GO:0016342 catenin complex(GO:0016342)
0.0 0.2 GO:0005744 mitochondrial inner membrane presequence translocase complex(GO:0005744)
0.0 0.1 GO:0070743 interleukin-12 complex(GO:0043514) interleukin-23 complex(GO:0070743)
0.0 0.1 GO:0005790 smooth endoplasmic reticulum(GO:0005790)
0.0 1.1 GO:0022625 cytosolic large ribosomal subunit(GO:0022625)
0.0 0.2 GO:0005751 mitochondrial respiratory chain complex IV(GO:0005751)
0.0 0.3 GO:0000164 protein phosphatase type 1 complex(GO:0000164)
0.0 0.1 GO:0016589 NURF complex(GO:0016589)
0.0 0.1 GO:0034098 VCP-NPL4-UFD1 AAA ATPase complex(GO:0034098)
0.0 0.4 GO:1902710 GABA receptor complex(GO:1902710) GABA-A receptor complex(GO:1902711)
0.0 0.0 GO:0019815 B cell receptor complex(GO:0019815)
0.0 0.1 GO:0014704 intercalated disc(GO:0014704)
0.0 0.2 GO:0000940 condensed chromosome outer kinetochore(GO:0000940)
0.0 0.2 GO:0042571 immunoglobulin complex, circulating(GO:0042571)
0.0 0.1 GO:0036157 outer dynein arm(GO:0036157)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.4 GO:1990430 extracellular matrix protein binding(GO:1990430)
0.1 1.5 GO:0031720 haptoglobin binding(GO:0031720)
0.1 0.4 GO:0004904 interferon receptor activity(GO:0004904)
0.1 0.7 GO:0004332 fructose-bisphosphate aldolase activity(GO:0004332)
0.1 0.4 GO:0004739 pyruvate dehydrogenase (acetyl-transferring) activity(GO:0004739)
0.1 0.4 GO:0030548 acetylcholine receptor regulator activity(GO:0030548) neurotransmitter receptor regulator activity(GO:0099602)
0.1 1.1 GO:0042813 Wnt-activated receptor activity(GO:0042813)
0.1 0.2 GO:0000810 diacylglycerol diphosphate phosphatase activity(GO:0000810)
0.1 0.2 GO:0034513 box H/ACA snoRNA binding(GO:0034513)
0.1 0.4 GO:0001972 retinoic acid binding(GO:0001972)
0.0 0.1 GO:0000293 ferric-chelate reductase activity(GO:0000293)
0.0 0.3 GO:0004392 heme oxygenase (decyclizing) activity(GO:0004392)
0.0 0.5 GO:0004046 aminoacylase activity(GO:0004046)
0.0 0.1 GO:0070259 tyrosyl-DNA phosphodiesterase activity(GO:0070259)
0.0 0.4 GO:0005113 patched binding(GO:0005113)
0.0 0.2 GO:0042169 SH2 domain binding(GO:0042169)
0.0 0.3 GO:0004563 beta-N-acetylhexosaminidase activity(GO:0004563)
0.0 0.2 GO:0015450 P-P-bond-hydrolysis-driven protein transmembrane transporter activity(GO:0015450)
0.0 0.3 GO:0004865 protein serine/threonine phosphatase inhibitor activity(GO:0004865)
0.0 0.1 GO:0004969 histamine receptor activity(GO:0004969)
0.0 0.2 GO:0004748 ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor(GO:0004748) oxidoreductase activity, acting on CH or CH2 groups, disulfide as acceptor(GO:0016728) ribonucleoside-diphosphate reductase activity(GO:0061731)
0.0 0.1 GO:0070224 sulfide:quinone oxidoreductase activity(GO:0070224)
0.0 0.2 GO:0015288 porin activity(GO:0015288)
0.0 0.1 GO:0004069 L-aspartate:2-oxoglutarate aminotransferase activity(GO:0004069)
0.0 0.1 GO:0034416 bisphosphoglycerate phosphatase activity(GO:0034416)
0.0 0.1 GO:0005219 ryanodine-sensitive calcium-release channel activity(GO:0005219) calcium-induced calcium release activity(GO:0048763)
0.0 0.1 GO:0004394 heparan sulfate 2-O-sulfotransferase activity(GO:0004394)
0.0 0.1 GO:0000048 peptidyltransferase activity(GO:0000048) glutathione hydrolase activity(GO:0036374)
0.0 0.1 GO:0004966 galanin receptor activity(GO:0004966)
0.0 0.2 GO:0032977 membrane insertase activity(GO:0032977)
0.0 0.3 GO:0047676 arachidonate-CoA ligase activity(GO:0047676)
0.0 1.3 GO:0015020 glucuronosyltransferase activity(GO:0015020)
0.0 0.2 GO:0015186 L-glutamine transmembrane transporter activity(GO:0015186)
0.0 0.7 GO:0003823 antigen binding(GO:0003823)
0.0 0.2 GO:0015467 G-protein activated inward rectifier potassium channel activity(GO:0015467)
0.0 0.6 GO:0016769 transferase activity, transferring nitrogenous groups(GO:0016769)
0.0 0.1 GO:0042164 interleukin-12 binding(GO:0019972) interleukin-12 alpha subunit binding(GO:0042164)
0.0 0.3 GO:2001069 glycogen binding(GO:2001069)
0.0 0.1 GO:0008508 bile acid:sodium symporter activity(GO:0008508)
0.0 0.2 GO:0004791 thioredoxin-disulfide reductase activity(GO:0004791)
0.0 0.1 GO:0061133 endopeptidase activator activity(GO:0061133)
0.0 0.2 GO:0008532 N-acetyllactosaminide beta-1,3-N-acetylglucosaminyltransferase activity(GO:0008532)
0.0 0.2 GO:0043515 kinetochore binding(GO:0043515)
0.0 0.2 GO:0004687 myosin light chain kinase activity(GO:0004687)
0.0 0.0 GO:0008022 protein C-terminus binding(GO:0008022)
0.0 0.2 GO:0052796 exo-alpha-(2->3)-sialidase activity(GO:0052794) exo-alpha-(2->6)-sialidase activity(GO:0052795) exo-alpha-(2->8)-sialidase activity(GO:0052796)
0.0 0.2 GO:0005021 vascular endothelial growth factor-activated receptor activity(GO:0005021)
0.0 0.3 GO:0051011 microtubule minus-end binding(GO:0051011)
0.0 1.2 GO:1902936 phosphatidylinositol bisphosphate binding(GO:1902936)
0.0 1.4 GO:0045296 cadherin binding(GO:0045296)
0.0 0.1 GO:0019202 amino acid kinase activity(GO:0019202)
0.0 0.1 GO:0004705 JUN kinase activity(GO:0004705) SAP kinase activity(GO:0016909)
0.0 0.1 GO:0042609 CD4 receptor binding(GO:0042609)
0.0 0.1 GO:0004134 glycogen debranching enzyme activity(GO:0004133) 4-alpha-glucanotransferase activity(GO:0004134) amylo-alpha-1,6-glucosidase activity(GO:0004135)
0.0 0.1 GO:0030942 endoplasmic reticulum signal peptide binding(GO:0030942)
0.0 0.4 GO:0004890 GABA-A receptor activity(GO:0004890)
0.0 0.3 GO:0005154 epidermal growth factor receptor binding(GO:0005154)
0.0 0.1 GO:0017040 ceramidase activity(GO:0017040)
0.0 0.2 GO:0008301 DNA binding, bending(GO:0008301)
0.0 0.1 GO:0003956 NAD(P)+-protein-arginine ADP-ribosyltransferase activity(GO:0003956)
0.0 0.3 GO:0008376 acetylgalactosaminyltransferase activity(GO:0008376)
0.0 0.2 GO:0050136 NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.7 PID THROMBIN PAR4 PATHWAY PAR4-mediated thrombin signaling events
0.0 0.8 PID WNT SIGNALING PATHWAY Wnt signaling network
0.0 0.2 SA MMP CYTOKINE CONNECTION Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix.
0.0 0.5 PID HNF3B PATHWAY FOXA2 and FOXA3 transcription factor networks

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.7 REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.0 0.9 REACTOME COMPLEMENT CASCADE Genes involved in Complement cascade
0.0 0.6 REACTOME GLYCOLYSIS Genes involved in Glycolysis
0.0 0.1 REACTOME PROSTACYCLIN SIGNALLING THROUGH PROSTACYCLIN RECEPTOR Genes involved in Prostacyclin signalling through prostacyclin receptor
0.0 0.2 REACTOME IL 6 SIGNALING Genes involved in Interleukin-6 signaling
0.0 0.0 REACTOME ACETYLCHOLINE NEUROTRANSMITTER RELEASE CYCLE Genes involved in Acetylcholine Neurotransmitter Release Cycle
0.0 0.1 REACTOME ACTIVATION OF THE AP1 FAMILY OF TRANSCRIPTION FACTORS Genes involved in Activation of the AP-1 family of transcription factors
0.0 0.2 REACTOME PTM GAMMA CARBOXYLATION HYPUSINE FORMATION AND ARYLSULFATASE ACTIVATION Genes involved in PTM: gamma carboxylation, hypusine formation and arylsulfatase activation
0.0 0.3 REACTOME CYTOCHROME P450 ARRANGED BY SUBSTRATE TYPE Genes involved in Cytochrome P450 - arranged by substrate type
0.0 0.2 REACTOME SYNTHESIS AND INTERCONVERSION OF NUCLEOTIDE DI AND TRIPHOSPHATES Genes involved in Synthesis and interconversion of nucleotide di- and triphosphates
0.0 0.6 REACTOME CLASS B 2 SECRETIN FAMILY RECEPTORS Genes involved in Class B/2 (Secretin family receptors)
0.0 0.1 REACTOME REGULATION OF PYRUVATE DEHYDROGENASE PDH COMPLEX Genes involved in Regulation of pyruvate dehydrogenase (PDH) complex