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PRJNA195909:zebrafish embryo and larva development
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Results for neurod1
Z-value: 1.05
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Transcription factors associated with neurod1
Activity-expression correlation:
| Gene | Promoter | Pearson corr. coef. | P-value | Plot |
|---|---|---|---|---|
| neurod1 | dr11_v1_chr9_-_44295071_44295071 | 0.30 | 4.3e-01 | Click! |
| Promoter | Log-likelihood | Transcript | Gene | Gene Info |
|---|---|---|---|---|
| chr25_-_554142 Show fit | 0.84 |
ENSDART00000028997
|
myosin IXAb |
|
| chr3_-_50443607 Show fit | 0.61 |
ENSDART00000074036
|
recoverin a |
|
| chr11_-_28911172 Show fit | 0.57 |
ENSDART00000168493
|
immunoglobin superfamily, member 21a |
|
| chr9_-_1200187 Show fit | 0.56 |
ENSDART00000158760
|
INO80 complex subunit Da |
|
| chr8_-_26609259 Show fit | 0.56 |
ENSDART00000027301
|
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3B |
|
| chr1_+_21937201 Show fit | 0.55 |
ENSDART00000087729
|
lysine (K)-specific demethylase 4C |
|
| chr12_+_21525496 Show fit | 0.53 |
ENSDART00000152974
|
carbonic anhydrase Xa |
|
| chr2_+_50626476 Show fit | 0.52 |
ENSDART00000018150
|
neuronal differentiation 6b |
|
| chr21_-_13085242 Show fit | 0.49 |
ENSDART00000044504
|
zgc:109965 |
|
| chr6_-_9565526 Show fit | 0.48 |
ENSDART00000151470
|
mitogen-activated protein kinase kinase kinase 2 |
Network of associatons between targets according to the STRING database.
First level regulatory network of neurod1
Gene Ontology Analysis
Gene overrepresentation in biological process category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.2 | 0.8 | GO:0098529 | neuromuscular junction development, skeletal muscle fiber(GO:0098529) |
| 0.0 | 0.7 | GO:0061512 | protein localization to cilium(GO:0061512) |
| 0.0 | 0.7 | GO:0048843 | negative regulation of axon extension involved in axon guidance(GO:0048843) negative regulation of axon guidance(GO:1902668) |
| 0.1 | 0.6 | GO:0036368 | cone photoresponse recovery(GO:0036368) |
| 0.0 | 0.6 | GO:0006208 | pyrimidine nucleobase catabolic process(GO:0006208) nucleobase catabolic process(GO:0046113) |
| 0.0 | 0.6 | GO:0016525 | negative regulation of angiogenesis(GO:0016525) |
| 0.2 | 0.5 | GO:1990868 | response to chemokine(GO:1990868) cellular response to chemokine(GO:1990869) negative regulation of lymphocyte migration(GO:2000402) negative regulation of T cell migration(GO:2000405) |
| 0.0 | 0.5 | GO:0002031 | G-protein coupled receptor internalization(GO:0002031) |
| 0.0 | 0.5 | GO:1901385 | regulation of voltage-gated calcium channel activity(GO:1901385) |
| 0.0 | 0.5 | GO:0071542 | dopaminergic neuron differentiation(GO:0071542) |
Gene overrepresentation in cellular component category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 0.8 | GO:0030426 | growth cone(GO:0030426) |
| 0.0 | 0.7 | GO:0000159 | protein phosphatase type 2A complex(GO:0000159) |
| 0.0 | 0.6 | GO:0043204 | perikaryon(GO:0043204) |
| 0.1 | 0.3 | GO:0035339 | SPOTS complex(GO:0035339) |
| 0.1 | 0.3 | GO:0005797 | Golgi medial cisterna(GO:0005797) |
| 0.0 | 0.3 | GO:0042583 | chromaffin granule(GO:0042583) |
| 0.0 | 0.3 | GO:0060170 | ciliary membrane(GO:0060170) |
| 0.0 | 0.3 | GO:0005771 | multivesicular body(GO:0005771) |
| 0.0 | 0.3 | GO:0048788 | cytoskeleton of presynaptic active zone(GO:0048788) |
| 0.0 | 0.2 | GO:0033010 | paranodal junction(GO:0033010) |
Gene overrepresentation in molecular function category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 0.8 | GO:0004683 | calmodulin-dependent protein kinase activity(GO:0004683) |
| 0.0 | 0.7 | GO:0001540 | beta-amyloid binding(GO:0001540) |
| 0.0 | 0.6 | GO:0004157 | dihydropyrimidinase activity(GO:0004157) |
| 0.0 | 0.6 | GO:0051864 | histone demethylase activity (H3-K36 specific)(GO:0051864) |
| 0.0 | 0.6 | GO:0038191 | neuropilin binding(GO:0038191) |
| 0.0 | 0.6 | GO:0008331 | high voltage-gated calcium channel activity(GO:0008331) |
| 0.1 | 0.5 | GO:0051430 | mu-type opioid receptor binding(GO:0031852) corticotropin-releasing hormone receptor 1 binding(GO:0051430) |
| 0.1 | 0.5 | GO:0034452 | dynactin binding(GO:0034452) |
| 0.0 | 0.5 | GO:0004089 | carbonate dehydratase activity(GO:0004089) |
| 0.0 | 0.4 | GO:0004706 | JUN kinase kinase kinase activity(GO:0004706) |
Gene overrepresentation in curated gene sets: canonical pathways category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 0.8 | PID MAPK TRK PATHWAY | Trk receptor signaling mediated by the MAPK pathway |
| 0.0 | 0.8 | NABA ECM AFFILIATED | Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins |
| 0.0 | 0.6 | PID RAC1 REG PATHWAY | Regulation of RAC1 activity |
| 0.0 | 0.5 | PID ECADHERIN STABILIZATION PATHWAY | Stabilization and expansion of the E-cadherin adherens junction |
| 0.0 | 0.4 | NABA PROTEOGLYCANS | Genes encoding proteoglycans |
| 0.0 | 0.4 | PID NFKAPPAB CANONICAL PATHWAY | Canonical NF-kappaB pathway |
| 0.0 | 0.3 | PID INSULIN GLUCOSE PATHWAY | Insulin-mediated glucose transport |
| 0.0 | 0.2 | PID S1P S1P4 PATHWAY | S1P4 pathway |
| 0.0 | 0.2 | PID SMAD2 3PATHWAY | Regulation of cytoplasmic and nuclear SMAD2/3 signaling |
| 0.0 | 0.2 | PID WNT CANONICAL PATHWAY | Canonical Wnt signaling pathway |
Gene overrepresentation in curated gene sets: REACTOME pathways category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.1 | 0.6 | REACTOME CRMPS IN SEMA3A SIGNALING | Genes involved in CRMPs in Sema3A signaling |
| 0.0 | 0.6 | REACTOME REGULATION OF GENE EXPRESSION IN BETA CELLS | Genes involved in Regulation of gene expression in beta cells |
| 0.0 | 0.4 | REACTOME P75NTR RECRUITS SIGNALLING COMPLEXES | Genes involved in p75NTR recruits signalling complexes |
| 0.0 | 0.4 | REACTOME CS DS DEGRADATION | Genes involved in CS/DS degradation |
| 0.0 | 0.4 | REACTOME GABA A RECEPTOR ACTIVATION | Genes involved in GABA A receptor activation |
| 0.0 | 0.4 | REACTOME ASSOCIATION OF TRIC CCT WITH TARGET PROTEINS DURING BIOSYNTHESIS | Genes involved in Association of TriC/CCT with target proteins during biosynthesis |
| 0.0 | 0.3 | REACTOME STRIATED MUSCLE CONTRACTION | Genes involved in Striated Muscle Contraction |
| 0.0 | 0.2 | REACTOME ACTIVATION OF CHAPERONE GENES BY ATF6 ALPHA | Genes involved in Activation of Chaperone Genes by ATF6-alpha |
| 0.0 | 0.2 | REACTOME SIGNALING BY NODAL | Genes involved in Signaling by NODAL |
| 0.0 | 0.2 | REACTOME SYNTHESIS SECRETION AND INACTIVATION OF GIP | Genes involved in Synthesis, Secretion, and Inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP) |