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PRJNA195909:zebrafish embryo and larva development

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Results for mycb

Z-value: 1.21

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Transcription factors associated with mycb

Gene Symbol Gene ID Gene Info
ENSDARG00000007241 MYC proto-oncogene, bHLH transcription factor b

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
mycbdr11_v1_chr2_+_32016256_32016256-0.314.2e-01Click!

Activity profile of mycb motif

Sorted Z-values of mycb motif

Promoter Log-likelihood Transcript Gene Gene Info
chr19_-_24555935 3.17 ENSDART00000132660
ENSDART00000162801
polymerase (RNA) III (DNA directed) polypeptide G like a
chr19_-_24555623 3.09 ENSDART00000176022
polymerase (RNA) III (DNA directed) polypeptide G like a
chr23_+_38159715 2.10 ENSDART00000137969
zgc:112994
chr23_-_28025943 1.89 ENSDART00000181146
Sp5 transcription factor-like
chr5_-_8765428 1.84 ENSDART00000167793
MYB binding protein (P160) 1a
chr9_-_56272465 1.32 ENSDART00000039235
lymphocyte cytosolic protein 1 (L-plastin)
chr5_+_68807170 1.25 ENSDART00000017849
hairy and enhancer of split related-7
chr1_-_19648227 0.96 ENSDART00000054574
polymerase (RNA) I polypeptide E
chr9_+_38158570 0.94 ENSDART00000059549
ENSDART00000133060
nucleolar protein interacting with the FHA domain of MKI67
chr14_-_12822 0.91 ENSDART00000180650
ENSDART00000188819
muscle segment homeobox 1a
chr14_-_28568107 0.89 ENSDART00000042850
ENSDART00000145502
preproinsulin b
chr22_-_26834043 0.87 ENSDART00000087202
si:dkey-44g23.5
chr16_+_23960933 0.86 ENSDART00000146077
apolipoprotein Eb
chr2_+_18988407 0.84 ENSDART00000170216
glutamate-ammonia ligase (glutamine synthase) a
chr16_+_23960744 0.79 ENSDART00000058965
apolipoprotein Eb
chr9_-_12652984 0.76 ENSDART00000052256
small ubiquitin-like modifier 3b
chr8_+_46386601 0.75 ENSDART00000129661
ENSDART00000084081
8-oxoguanine DNA glycosylase
chr11_+_3959495 0.74 ENSDART00000122953
guanine nucleotide binding protein-like 3 (nucleolar)
chr13_-_45022301 0.74 ENSDART00000183589
ENSDART00000125633
ENSDART00000074787
KH domain containing, RNA binding, signal transduction associated 1a
chr16_+_23961276 0.69 ENSDART00000192754
apolipoprotein Eb
chr13_-_9367647 0.66 ENSDART00000083362
ENSDART00000144146
si:dkey-33c12.4
chr4_-_890220 0.66 ENSDART00000022668
crystallin beta-gamma domain containing 1b
chr5_-_61609448 0.65 ENSDART00000133426
si:dkey-261j4.5
chr11_+_6456146 0.65 ENSDART00000036939
growth arrest and DNA-damage-inducible, beta a
chr19_+_42328423 0.65 ENSDART00000077059
acidic (leucine-rich) nuclear phosphoprotein 32 family, member E
chr17_+_24318753 0.64 ENSDART00000064083
orthodenticle homeobox 1
chr21_-_30408775 0.62 ENSDART00000101037
NHP2 ribonucleoprotein homolog (yeast)
chr10_+_39283985 0.62 ENSDART00000016464
decapping enzyme, scavenger
chr17_-_48705993 0.61 ENSDART00000030934
potassium channel, subfamily K, member 5a
chr13_-_4992395 0.57 ENSDART00000102651
nucleolar and coiled-body phosphoprotein 1
chr10_+_29849977 0.55 ENSDART00000180242
heat shock protein 8
chr19_-_791016 0.54 ENSDART00000037515
misato 1, mitochondrial distribution and morphology regulator
chr10_-_39283883 0.52 ENSDART00000023831
cryptochrome circadian clock 5
chr23_+_25135858 0.51 ENSDART00000103986
family with sequence similarity 3, member A
chr2_-_42375275 0.51 ENSDART00000026339
GTP binding protein 4
chr22_-_607812 0.50 ENSDART00000145983
cyclin-dependent kinase inhibitor 1A
chr15_+_6652396 0.49 ENSDART00000192813
ENSDART00000157678
NOP53 ribosome biogenesis factor
chr13_+_31402067 0.49 ENSDART00000019202
tudor domain containing 9
chr24_+_36317544 0.49 ENSDART00000048640
ENSDART00000156096
pseudouridylate synthase 3
chr12_-_7607114 0.47 ENSDART00000158095
solute carrier family 16, member 9b
chr9_-_11587070 0.47 ENSDART00000030995
uridine monophosphate synthetase
chr19_+_1005933 0.46 ENSDART00000191953
zinc finger, DHHC-type containing 3b
chr8_-_2246143 0.45 ENSDART00000135835
si:dkeyp-117b11.3
chr9_+_29985010 0.44 ENSDART00000020743
cms1 ribosomal small subunit homolog (yeast)
chr5_+_3927989 0.44 ENSDART00000030125
zinc finger, HIT-type containing 3
chr4_-_2945306 0.44 ENSDART00000128934
ENSDART00000019518
AE binding protein 2
chr1_+_17376922 0.43 ENSDART00000145068
FAT atypical cadherin 1a
chr10_+_29850330 0.43 ENSDART00000168898
heat shock protein 8
chr12_-_4301234 0.43 ENSDART00000152377
ENSDART00000152521
carbonic anhydrase XVb
chr25_+_17405458 0.43 ENSDART00000186711
E2F transcription factor 4
chr3_+_24595922 0.42 ENSDART00000169405
si:dkey-68o6.5
chr20_+_25625872 0.42 ENSDART00000078385
phosphoribosyl pyrophosphate amidotransferase
chr9_-_11676491 0.41 ENSDART00000022358
zinc finger CCCH-type containing 15
chr15_+_42235449 0.41 ENSDART00000114801
ENSDART00000182053
sphingosine-1-phosphate phosphatase 2
chr25_+_17405201 0.41 ENSDART00000164349
E2F transcription factor 4
chr8_-_46386024 0.40 ENSDART00000136602
ENSDART00000060919
ENSDART00000137472
glutaminyl-tRNA synthetase
chr1_-_54972170 0.40 ENSDART00000150548
ENSDART00000038330
KH-type splicing regulatory protein
chr17_+_13099476 0.40 ENSDART00000012670
pinin, desmosome associated protein
chr8_-_23599096 0.39 ENSDART00000183096
solute carrier family 38, member 5b
chr19_-_26964348 0.39 ENSDART00000103955
zinc finger and BTB domain containing 12, tandem duplicate 2
chr11_+_25296366 0.38 ENSDART00000065949
DNA topoisomerase I, like
chr11_-_30636163 0.38 ENSDART00000140516
zgc:153665
chr6_-_10752937 0.38 ENSDART00000135093
Obg-like ATPase 1
chr20_-_25631256 0.38 ENSDART00000048164
phosphoribosylaminoimidazole carboxylase, phosphoribosylaminoimidazole succinocarboxamide synthetase
chr9_-_27391908 0.37 ENSDART00000135221
nucleolus and neural progenitor protein
chr4_+_90048 0.37 ENSDART00000166440
low density lipoprotein receptor-related protein 6
chr6_-_39080630 0.37 ENSDART00000021520
ENSDART00000128308
eukaryotic translation initiation factor 4Bb
chr24_-_39518599 0.36 ENSDART00000145606
ENSDART00000031486
LYR motif containing 1
chr14_+_22076596 0.36 ENSDART00000106147
ENSDART00000100278
ENSDART00000131489
solute carrier family 43 (amino acid system L transporter), member 1a
chr21_-_14832369 0.36 ENSDART00000144859
pseudouridylate synthase 1
chr20_+_25445826 0.36 ENSDART00000012581
phosphoribosylformylglycinamidine synthase
chr1_-_54971968 0.35 ENSDART00000140016
KH-type splicing regulatory protein
chr20_-_25645150 0.34 ENSDART00000063137
si:dkeyp-117h8.4
chr23_-_38160024 0.34 ENSDART00000087112
prefoldin subunit 4
chr17_+_51682429 0.33 ENSDART00000004379
nucleolar protein 10
chr25_+_30442389 0.33 ENSDART00000003346
programmed cell death 2-like
chr14_+_16287968 0.32 ENSDART00000106593
pre-mRNA processing factor 19
chr23_-_21535040 0.32 ENSDART00000010647
regulator of chromosome condensation 2
chr4_+_36489448 0.32 ENSDART00000143181
zinc finger protein 1149
chr5_-_3927692 0.32 ENSDART00000146840
ENSDART00000058346
complement component 1, q subcomponent binding protein
chr6_-_58975010 0.32 ENSDART00000144911
ENSDART00000144514
methionyl-tRNA synthetase
chr3_-_23575007 0.31 ENSDART00000155282
ENSDART00000087726
insulin-like growth factor 2 mRNA binding protein 1
chr22_+_6293563 0.31 ENSDART00000063416
ribonuclease like 2
chr11_+_25485774 0.31 ENSDART00000026249
guanine nucleotide binding protein-like 3 (nucleolar)-like
chr9_-_21460164 0.30 ENSDART00000133469
zinc finger, MYM-type 2
chr23_-_21534455 0.30 ENSDART00000139092
regulator of chromosome condensation 2
chr21_-_45382112 0.30 ENSDART00000151029
ENSDART00000151335
ENSDART00000151687
ENSDART00000075438
CDKN2A interacting protein N-terminal like
chr16_-_31790285 0.29 ENSDART00000184655
chromodomain helicase DNA binding protein 4b
chr18_-_5850683 0.29 ENSDART00000082087
NIP7, nucleolar pre-rRNA processing protein
chr5_-_54714789 0.28 ENSDART00000063357
cyclin B1
chr7_+_1550966 0.28 ENSDART00000177863
ENSDART00000126840
SPT16 homolog, facilitates chromatin remodeling subunit
chr14_+_52408619 0.28 ENSDART00000163856
nitric oxide associated 1
chr22_+_5118361 0.26 ENSDART00000168371
ENSDART00000170222
ENSDART00000158846
muscle-specific beta 1 integrin binding protein
chr25_-_8513255 0.26 ENSDART00000150129
polymerase (DNA directed), gamma
chr23_-_21534738 0.26 ENSDART00000134587
regulator of chromosome condensation 2
chr1_-_14533611 0.25 ENSDART00000180678

chr13_+_13930263 0.25 ENSDART00000079154
ribose 5-phosphate isomerase A (ribose 5-phosphate epimerase)
chr19_-_22346582 0.25 ENSDART00000045675
ENSDART00000169065
solute carrier family 52 (riboflavin transporter), member 2
zgc:109744
chr24_+_32668675 0.25 ENSDART00000156638
ENSDART00000155973
si:ch211-282b22.1
chr22_+_10713713 0.25 ENSDART00000122349
hippocampus abundant transcript 1b
chr1_-_35916247 0.24 ENSDART00000181541
SMAD family member 1
chr21_+_3941758 0.24 ENSDART00000181345
senataxin
chr19_-_32804535 0.23 ENSDART00000175613
ENSDART00000052098
5'-nucleotidase, cytosolic IAa
chr16_-_21668082 0.23 ENSDART00000088513
guanine nucleotide binding protein-like 1
chr8_-_52859301 0.23 ENSDART00000162004
nuclear receptor subfamily 5, group A, member 1a
chr25_+_245438 0.22 ENSDART00000004689
zgc:92481
chr16_+_16968682 0.22 ENSDART00000111074
si:ch211-120k19.1
chr1_+_34203817 0.22 ENSDART00000191432
ENSDART00000046094
ADP-ribosylation factor-like 6
chr5_+_72194444 0.22 ENSDART00000165436
DEAD (Asp-Glu-Ala-Asp) box polypeptide 54
chr18_+_14277003 0.22 ENSDART00000006628
zgc:173742
chr2_-_10014821 0.22 ENSDART00000185525

chr7_-_26462831 0.22 ENSDART00000113543
metallo-beta-lactamase domain containing 1
chr6_-_54078623 0.21 ENSDART00000154076
hyaluronoglucosaminidase 1
chr8_-_40251126 0.21 ENSDART00000180435
lysine (K)-specific demethylase 2Ba
chr15_-_44052927 0.21 ENSDART00000166209
wu:fb44b02
chr4_+_18824959 0.21 ENSDART00000146141
ENSDART00000040424
solute carrier family 26 (anion exchanger), member 3
chr4_-_14192254 0.21 ENSDART00000143804
pseudouridylate synthase 7-like
chr14_+_20941038 0.20 ENSDART00000182539
zgc:66433
chr7_+_41322407 0.20 ENSDART00000114076
ENSDART00000139093
DPH2 homolog (S. cerevisiae)
chr2_+_19236969 0.19 ENSDART00000163875
ENSDART00000168644
coiled-coil and C2 domain containing 1B
chr16_+_16969060 0.19 ENSDART00000182819
ENSDART00000191876
si:ch211-120k19.1
ribosomal protein L18
chr6_-_39653972 0.18 ENSDART00000155859
La ribonucleoprotein domain family, member 4Ab
chr11_-_12800945 0.18 ENSDART00000191178
taxilin gamma
chr21_-_39577517 0.18 ENSDART00000143566
serine/arginine-rich splicing factor 1b
chr9_+_33788389 0.18 ENSDART00000144623
lysine (K)-specific demethylase 6A
chr11_-_12801157 0.17 ENSDART00000103449
taxilin gamma
chr19_+_791538 0.17 ENSDART00000146554
ENSDART00000138406
transmembrane protein 79a
chr25_+_19095231 0.17 ENSDART00000154066
interferon stimulated exonuclease gene
chr17_-_45370200 0.17 ENSDART00000186208
zinc finger protein 106a
chr8_+_23355484 0.16 ENSDART00000085361
ENSDART00000125729
DNA (cytosine-5-)-methyltransferase 3 beta, duplicate a
chr1_-_6494384 0.16 ENSDART00000109356
Kruppel-like factor 7a
chr24_-_42090635 0.16 ENSDART00000166413
signal sequence receptor, alpha
chr4_+_61171310 0.16 ENSDART00000141738
si:dkey-9p20.18
chr6_-_13114406 0.16 ENSDART00000188015
zgc:194469
chr12_-_3453589 0.16 ENSDART00000175918

chr4_-_38033800 0.15 ENSDART00000159662
si:dkeyp-82b4.4
chr9_-_27719998 0.15 ENSDART00000161068
ENSDART00000148195
ENSDART00000138386
general transcription factor IIE, polypeptide 1, alpha
chr9_-_27720612 0.15 ENSDART00000000566
general transcription factor IIE, polypeptide 1, alpha
chr5_-_54714525 0.15 ENSDART00000150138
ENSDART00000150070
cyclin B1
chr13_-_48431766 0.15 ENSDART00000159688
ENSDART00000171765
F-box protein 11a
chr21_+_38638979 0.14 ENSDART00000143373
RNA binding motif protein, X-linked 2
chr25_+_37443194 0.14 ENSDART00000163178
ENSDART00000190262
solute carrier family 10, member 3
chr3_-_40955780 0.14 ENSDART00000130130
cytochrome P450, family 3, subfamily c, polypeptide 3
chr8_-_13419049 0.14 ENSDART00000133656
Pim proto-oncogene, serine/threonine kinase, related 101
chr20_-_52882881 0.13 ENSDART00000111078
wu:fi04e12
chr19_+_7757682 0.13 ENSDART00000092138
ENSDART00000092112
ubiquitin associated protein 2-like
chr8_-_13471916 0.13 ENSDART00000146558
Pim proto-oncogene, serine/threonine kinase, related 105
chr13_-_18345854 0.13 ENSDART00000080107
si:dkey-228d14.5
chr2_+_9946121 0.12 ENSDART00000100696
TSEN15 tRNA splicing endonuclease subunit
chr21_-_11199366 0.12 ENSDART00000167666
DnaJ (Hsp40) homolog, subfamily C, member 21
chr5_-_41933912 0.12 ENSDART00000097574
nuclear receptor corepressor 1
chr10_+_16036573 0.12 ENSDART00000188757
lamin B1
chr4_-_44611273 0.12 ENSDART00000156793
zinc finger protein 1115
chr22_+_28969071 0.11 ENSDART00000163427
Pim proto-oncogene, serine/threonine kinase, related 95
chr21_-_34032650 0.11 ENSDART00000138575
ENSDART00000047515
ring finger protein 145b
chr9_+_27720428 0.11 ENSDART00000112415
leucine carboxyl methyltransferase 2
chr15_-_43978141 0.10 ENSDART00000041249
cysteine and histidine-rich domain (CHORD) containing 1a
chr10_+_16036246 0.10 ENSDART00000141586
ENSDART00000135868
ENSDART00000065037
ENSDART00000124502
lamin B1
chr13_+_15702142 0.10 ENSDART00000135960
tRNA methyltransferase 61A
chr9_-_904227 0.10 ENSDART00000144068
zgc:101851
chr19_+_24882845 0.10 ENSDART00000010580
si:ch211-195b13.1
chr13_+_48359573 0.09 ENSDART00000161959
ENSDART00000165311
mutS homolog 6 (E. coli)
chr13_-_35892051 0.09 ENSDART00000145884
transforming, acidic coiled-coil containing protein 3
chr1_-_26675969 0.09 ENSDART00000054184
tRNA methyltransferase O
chr16_-_38629208 0.09 ENSDART00000126705
eukaryotic translation initiation factor 3, subunit E, a
chr4_-_64709908 0.08 ENSDART00000161032
si:dkey-9i5.2
chr10_-_14929630 0.08 ENSDART00000121892
ENSDART00000044756
ENSDART00000128579
ENSDART00000147653
SMAD family member 2
chr2_+_19236677 0.08 ENSDART00000166292
coiled-coil and C2 domain containing 1B
chr10_+_428269 0.08 ENSDART00000140715
zinc finger, DHHC-type containing 8a
chr1_-_26676391 0.08 ENSDART00000152492
tRNA methyltransferase O
chr21_+_45387903 0.08 ENSDART00000186253
ENSDART00000075432
jade family PHD finger 2
chr16_+_13822137 0.07 ENSDART00000163251
folliculin
chr1_+_31674297 0.07 ENSDART00000044214
WW domain binding protein 1-like b
chr14_+_4796168 0.07 ENSDART00000041468
adaptor-related protein complex 1 associated regulatory protein
chr13_+_39277178 0.07 ENSDART00000113259
si:dkey-85a20.4
chr13_-_3516473 0.06 ENSDART00000146240
parkin RBR E3 ubiquitin protein ligase
chr24_+_39518774 0.06 ENSDART00000132939
defective in cullin neddylation 1 domain containing 3
chr22_+_17261801 0.06 ENSDART00000192978
ENSDART00000193187
ENSDART00000179953
ENSDART00000134798
tudor domain containing 5
chr14_+_5385855 0.06 ENSDART00000031508
ladybird homeobox 2
chr2_-_56387041 0.06 ENSDART00000036240
ceramide synthase 4b
chr5_-_1999417 0.06 ENSDART00000155437
ENSDART00000145781
si:ch211-160e1.5
chr8_-_30979494 0.06 ENSDART00000138959
si:ch211-251j10.3
chr21_+_45510448 0.05 ENSDART00000160494
ENSDART00000167914
folliculin interacting protein 1
chr9_+_1339194 0.05 ENSDART00000186976
ENSDART00000014766
caspase 8, apoptosis-related cysteine peptidase, like 2
chr24_+_16905188 0.05 ENSDART00000066760
chaperonin containing TCP1, subunit 5 (epsilon)
chr15_-_2632891 0.04 ENSDART00000081840
claudin j
chr9_-_12888082 0.04 ENSDART00000133135
ENSDART00000134415
si:ch211-167j6.3
chr20_-_48470599 0.04 ENSDART00000166857

chr21_+_19517492 0.04 ENSDART00000123168
ENSDART00000187993
granzyme K
chr22_+_1440702 0.04 ENSDART00000165677
si:dkeyp-53d3.3
chr7_+_33136545 0.04 ENSDART00000173485
intelectin 2
chr18_+_20225961 0.04 ENSDART00000045679
transducin-like enhancer of split 3a
chr1_-_29061285 0.03 ENSDART00000053933
ENSDART00000142350
ENSDART00000192615
gem (nuclear organelle) associated protein 8
chr9_+_907459 0.03 ENSDART00000034850
ENSDART00000144114
diazepam binding inhibitor (GABA receptor modulator, acyl-CoA binding protein)
chr13_-_280652 0.03 ENSDART00000193627
solute carrier family 30 (zinc transporter), member 6
chr7_-_28463106 0.02 ENSDART00000137799
tripartite motif containing 66
chr5_-_16475374 0.02 ENSDART00000134274
ENSDART00000136004
piwi-like RNA-mediated gene silencing 2
chr15_+_44053244 0.02 ENSDART00000059550
leucine rich repeat containing 51
chr3_-_47038481 0.02 ENSDART00000193260

chr3_+_57991074 0.02 ENSDART00000076077
myeloid-associated differentiation marker-like 2

Network of associatons between targets according to the STRING database.

First level regulatory network of mycb

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.8 2.3 GO:0071831 chylomicron remnant clearance(GO:0034382) triglyceride-rich lipoprotein particle clearance(GO:0071830) intermediate-density lipoprotein particle clearance(GO:0071831)
0.2 0.8 GO:1990481 mRNA pseudouridine synthesis(GO:1990481)
0.2 0.6 GO:0031120 snRNA pseudouridine synthesis(GO:0031120)
0.2 6.3 GO:0006383 transcription from RNA polymerase III promoter(GO:0006383)
0.2 1.0 GO:0042790 transcription of nuclear large rRNA transcript from RNA polymerase I promoter(GO:0042790)
0.2 1.0 GO:1902946 positive regulation of receptor-mediated endocytosis(GO:0048260) protein localization to early endosome(GO:1902946)
0.1 0.8 GO:0006542 glutamine biosynthetic process(GO:0006542)
0.1 1.0 GO:0006189 'de novo' IMP biosynthetic process(GO:0006189)
0.1 0.3 GO:0001120 DNA-templated transcriptional open complex formation(GO:0001112) transcriptional open complex formation at RNA polymerase II promoter(GO:0001113) protein-DNA complex remodeling(GO:0001120)
0.1 0.4 GO:1902024 L-histidine transmembrane transport(GO:0089709) L-histidine transport(GO:1902024)
0.1 0.5 GO:0044205 'de novo' UMP biosynthetic process(GO:0044205)
0.1 0.7 GO:1904035 epithelial cell apoptotic process(GO:1904019) regulation of epithelial cell apoptotic process(GO:1904035)
0.1 0.6 GO:0000290 deadenylation-dependent decapping of nuclear-transcribed mRNA(GO:0000290)
0.1 0.5 GO:0045721 negative regulation of gluconeogenesis(GO:0045721)
0.1 0.3 GO:0043518 negative regulation of DNA damage response, signal transduction by p53 class mediator(GO:0043518)
0.1 0.3 GO:0070131 regulation of mitochondrial translation(GO:0070129) positive regulation of mitochondrial translation(GO:0070131)
0.1 1.4 GO:0000463 maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000463)
0.1 0.7 GO:0000467 exonucleolytic trimming involved in rRNA processing(GO:0000459) exonucleolytic trimming to generate mature 3'-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000467)
0.1 0.5 GO:0007141 male meiosis I(GO:0007141)
0.1 0.7 GO:0006285 base-excision repair, AP site formation(GO:0006285)
0.1 1.3 GO:0051639 actin filament network formation(GO:0051639)
0.1 1.9 GO:0036342 post-anal tail morphogenesis(GO:0036342)
0.1 0.4 GO:0097010 eukaryotic translation initiation factor 4F complex assembly(GO:0097010)
0.1 0.3 GO:0009052 pentose-phosphate shunt, non-oxidative branch(GO:0009052)
0.0 0.4 GO:0007080 mitotic metaphase plate congression(GO:0007080)
0.0 1.3 GO:0001757 somite specification(GO:0001757)
0.0 0.3 GO:0032218 riboflavin transport(GO:0032218)
0.0 0.3 GO:1902262 apoptotic process involved in patterning of blood vessels(GO:1902262)
0.0 0.5 GO:0010165 response to X-ray(GO:0010165)
0.0 0.6 GO:0003406 retinal pigment epithelium development(GO:0003406)
0.0 0.1 GO:0031591 wybutosine metabolic process(GO:0031590) wybutosine biosynthetic process(GO:0031591)
0.0 0.6 GO:0006265 DNA topological change(GO:0006265)
0.0 0.2 GO:0006369 termination of RNA polymerase II transcription(GO:0006369)
0.0 0.2 GO:0017182 peptidyl-diphthamide metabolic process(GO:0017182) peptidyl-diphthamide biosynthetic process from peptidyl-histidine(GO:0017183)
0.0 0.1 GO:0016446 somatic diversification of immune receptors via somatic mutation(GO:0002566) pyrimidine dimer repair(GO:0006290) somatic hypermutation of immunoglobulin genes(GO:0016446)
0.0 0.3 GO:0034724 DNA replication-independent nucleosome organization(GO:0034724)
0.0 0.6 GO:0008354 germ cell migration(GO:0008354)
0.0 0.1 GO:1904105 positive regulation of convergent extension involved in gastrulation(GO:1904105)
0.0 0.3 GO:0006264 mitochondrial DNA replication(GO:0006264)
0.0 0.9 GO:0043049 otic placode formation(GO:0043049)
0.0 0.6 GO:0043486 histone exchange(GO:0043486)
0.0 0.8 GO:0016925 protein sumoylation(GO:0016925)
0.0 0.5 GO:0043153 entrainment of circadian clock by photoperiod(GO:0043153)
0.0 0.6 GO:0030322 stabilization of membrane potential(GO:0030322)
0.0 0.2 GO:0030325 adrenal gland development(GO:0030325)
0.0 0.5 GO:0000027 ribosomal large subunit assembly(GO:0000027)
0.0 0.4 GO:0045747 positive regulation of Notch signaling pathway(GO:0045747)
0.0 0.2 GO:0046085 adenosine metabolic process(GO:0046085)
0.0 0.1 GO:0010812 negative regulation of cell-substrate adhesion(GO:0010812)
0.0 0.3 GO:0048311 mitochondrion distribution(GO:0048311)
0.0 0.2 GO:0030214 hyaluronan catabolic process(GO:0030214)
0.0 0.3 GO:0050829 defense response to Gram-negative bacterium(GO:0050829)
0.0 0.4 GO:0044332 Wnt signaling pathway involved in dorsal/ventral axis specification(GO:0044332)
0.0 0.1 GO:0060282 positive regulation of oocyte development(GO:0060282)
0.0 0.1 GO:0006388 tRNA splicing, via endonucleolytic cleavage and ligation(GO:0006388)
0.0 0.5 GO:0018231 peptidyl-L-cysteine S-palmitoylation(GO:0018230) peptidyl-S-diacylglycerol-L-cysteine biosynthetic process from peptidyl-cysteine(GO:0018231)
0.0 0.4 GO:0016339 calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0016339)
0.0 0.2 GO:0009651 response to salt stress(GO:0009651)
0.0 0.3 GO:0042255 ribosome assembly(GO:0042255)
0.0 0.2 GO:0001522 pseudouridine synthesis(GO:0001522)
0.0 0.1 GO:0030511 positive regulation of transforming growth factor beta receptor signaling pathway(GO:0030511) positive regulation of cellular response to transforming growth factor beta stimulus(GO:1903846)
0.0 0.3 GO:0000462 maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000462)
0.0 0.1 GO:0015721 bile acid and bile salt transport(GO:0015721)
0.0 0.3 GO:0015804 neutral amino acid transport(GO:0015804)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 2.3 GO:0034363 intermediate-density lipoprotein particle(GO:0034363)
0.3 6.3 GO:0005666 DNA-directed RNA polymerase III complex(GO:0005666)
0.2 1.0 GO:0005736 DNA-directed RNA polymerase I complex(GO:0005736)
0.2 0.6 GO:0072588 box H/ACA snoRNP complex(GO:0031429) box H/ACA RNP complex(GO:0072588)
0.1 0.4 GO:0097125 cyclin B1-CDK1 complex(GO:0097125)
0.1 0.6 GO:0000812 Swr1 complex(GO:0000812)
0.1 0.3 GO:0005673 transcription factor TFIIE complex(GO:0005673)
0.1 0.3 GO:0071006 U2-type catalytic step 1 spliceosome(GO:0071006) catalytic step 1 spliceosome(GO:0071012)
0.0 0.3 GO:0016272 prefoldin complex(GO:0016272)
0.0 0.3 GO:0042645 nucleoid(GO:0009295) mitochondrial nucleoid(GO:0042645)
0.0 0.3 GO:0070937 CRD-mediated mRNA stability complex(GO:0070937)
0.0 0.4 GO:0035098 ESC/E(Z) complex(GO:0035098)
0.0 0.1 GO:0032301 MutSalpha complex(GO:0032301)
0.0 1.3 GO:0032587 ruffle membrane(GO:0032587)
0.0 8.5 GO:0005730 nucleolus(GO:0005730)
0.0 0.9 GO:0010494 cytoplasmic stress granule(GO:0010494)
0.0 0.3 GO:0035101 FACT complex(GO:0035101)
0.0 0.1 GO:0033391 chromatoid body(GO:0033391)
0.0 0.4 GO:0030057 desmosome(GO:0030057)
0.0 0.1 GO:0031515 tRNA (m1A) methyltransferase complex(GO:0031515)
0.0 0.1 GO:0071540 eukaryotic translation initiation factor 3 complex, eIF3e(GO:0071540)
0.0 0.5 GO:0043186 P granule(GO:0043186)
0.0 0.3 GO:0071144 SMAD2-SMAD3 protein complex(GO:0071144)
0.0 0.1 GO:0014704 intercalated disc(GO:0014704)
0.0 0.1 GO:0016580 Sin3 complex(GO:0016580)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.8 2.3 GO:0043395 heparan sulfate proteoglycan binding(GO:0043395)
0.2 0.6 GO:0034513 box H/ACA snoRNA binding(GO:0034513)
0.2 0.7 GO:0000702 oxidized base lesion DNA N-glycosylase activity(GO:0000702)
0.2 0.5 GO:0003913 DNA photolyase activity(GO:0003913)
0.1 0.8 GO:0016211 glutamate-ammonia ligase activity(GO:0004356) ammonia ligase activity(GO:0016211) acid-ammonia (or amide) ligase activity(GO:0016880)
0.1 0.5 GO:0008097 5S rRNA binding(GO:0008097)
0.1 0.4 GO:0004639 phosphoribosylaminoimidazolesuccinocarboxamide synthase activity(GO:0004639)
0.1 0.2 GO:0001147 transcription termination site sequence-specific DNA binding(GO:0001147) transcription termination site DNA binding(GO:0001160)
0.1 0.6 GO:0050072 m7G(5')pppN diphosphatase activity(GO:0050072)
0.1 0.8 GO:0017091 AU-rich element binding(GO:0017091) mRNA 3'-UTR AU-rich region binding(GO:0035925)
0.1 1.0 GO:0044183 protein binding involved in protein folding(GO:0044183)
0.1 0.4 GO:0043023 ribosomal large subunit binding(GO:0043023)
0.1 0.5 GO:0004861 cyclin-dependent protein serine/threonine kinase inhibitor activity(GO:0004861)
0.1 1.0 GO:0009982 pseudouridine synthase activity(GO:0009982)
0.1 0.4 GO:0033592 RNA strand annealing activity(GO:0033592) RNA strand-exchange activity(GO:0034057)
0.0 0.8 GO:0031386 protein tag(GO:0031386)
0.0 0.6 GO:0003917 DNA topoisomerase type I activity(GO:0003917)
0.0 0.3 GO:0032217 riboflavin transporter activity(GO:0032217)
0.0 0.3 GO:0016426 tRNA (adenine) methyltransferase activity(GO:0016426)
0.0 0.3 GO:0050262 ribosylnicotinamide kinase activity(GO:0050262)
0.0 1.0 GO:0034062 DNA-directed RNA polymerase activity(GO:0003899) RNA polymerase activity(GO:0034062)
0.0 0.3 GO:0008494 translation activator activity(GO:0008494)
0.0 0.7 GO:0008143 poly(A) binding(GO:0008143)
0.0 0.4 GO:0015186 L-glutamine transmembrane transporter activity(GO:0015186)
0.0 0.1 GO:0032404 guanine/thymine mispair binding(GO:0032137) single base insertion or deletion binding(GO:0032138) single thymine insertion binding(GO:0032143) oxidized DNA binding(GO:0032356) oxidized purine DNA binding(GO:0032357) mismatch repair complex binding(GO:0032404) MutLalpha complex binding(GO:0032405)
0.0 0.4 GO:0016884 carbon-nitrogen ligase activity, with glutamine as amido-N-donor(GO:0016884)
0.0 0.1 GO:0008508 bile acid:sodium symporter activity(GO:0008508)
0.0 0.6 GO:0022842 leak channel activity(GO:0022840) potassium ion leak channel activity(GO:0022841) narrow pore channel activity(GO:0022842)
0.0 0.4 GO:0042813 Wnt-activated receptor activity(GO:0042813)
0.0 0.3 GO:0016861 intramolecular oxidoreductase activity, interconverting aldoses and ketoses(GO:0016861)
0.0 0.2 GO:0071558 histone demethylase activity (H3-K27 specific)(GO:0071558)
0.0 0.2 GO:0004415 hyalurononglucosaminidase activity(GO:0004415)
0.0 0.3 GO:0070411 I-SMAD binding(GO:0070411)
0.0 0.4 GO:0004089 carbonate dehydratase activity(GO:0004089)
0.0 0.1 GO:0046966 thyroid hormone receptor binding(GO:0046966)
0.0 0.2 GO:0008510 sodium:bicarbonate symporter activity(GO:0008510)
0.0 0.6 GO:0019212 phosphatase inhibitor activity(GO:0019212)
0.0 0.2 GO:0003886 DNA (cytosine-5-)-methyltransferase activity(GO:0003886)
0.0 0.3 GO:0003887 DNA-directed DNA polymerase activity(GO:0003887)
0.0 0.5 GO:0019707 protein-cysteine S-palmitoyltransferase activity(GO:0019706) protein-cysteine S-acyltransferase activity(GO:0019707)
0.0 0.5 GO:0016831 carboxy-lyase activity(GO:0016831)
0.0 0.2 GO:0008253 5'-nucleotidase activity(GO:0008253)
0.0 0.1 GO:0042030 ATPase inhibitor activity(GO:0042030)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.8 SA REG CASCADE OF CYCLIN EXPR Expression of cyclins regulates progression through the cell cycle by activating cyclin-dependent kinases.
0.0 0.5 SA G2 AND M PHASES Cdc25 activates the cdc2/cyclin B complex to induce the G2/M transition.
0.0 0.4 PID WNT CANONICAL PATHWAY Canonical Wnt signaling pathway
0.0 0.2 PID ALK2 PATHWAY ALK2 signaling events
0.0 0.7 PID TAP63 PATHWAY Validated transcriptional targets of TAp63 isoforms
0.0 1.1 PID CMYB PATHWAY C-MYB transcription factor network
0.0 0.4 PID FRA PATHWAY Validated transcriptional targets of AP1 family members Fra1 and Fra2
0.0 0.2 PID ERB GENOMIC PATHWAY Validated nuclear estrogen receptor beta network
0.0 0.6 SIG PIP3 SIGNALING IN CARDIAC MYOCTES Genes related to PIP3 signaling in cardiac myocytes

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.8 REACTOME DESTABILIZATION OF MRNA BY KSRP Genes involved in Destabilization of mRNA by KSRP
0.1 1.0 REACTOME GABA SYNTHESIS RELEASE REUPTAKE AND DEGRADATION Genes involved in GABA synthesis, release, reuptake and degradation
0.1 1.0 REACTOME PURINE RIBONUCLEOSIDE MONOPHOSPHATE BIOSYNTHESIS Genes involved in Purine ribonucleoside monophosphate biosynthesis
0.1 0.7 REACTOME BASE FREE SUGAR PHOSPHATE REMOVAL VIA THE SINGLE NUCLEOTIDE REPLACEMENT PATHWAY Genes involved in Base-free sugar-phosphate removal via the single-nucleotide replacement pathway
0.1 0.6 REACTOME MRNA DECAY BY 3 TO 5 EXORIBONUCLEASE Genes involved in mRNA Decay by 3' to 5' Exoribonuclease
0.0 0.4 REACTOME RECRUITMENT OF NUMA TO MITOTIC CENTROSOMES Genes involved in Recruitment of NuMA to mitotic centrosomes
0.0 0.5 REACTOME AKT PHOSPHORYLATES TARGETS IN THE CYTOSOL Genes involved in AKT phosphorylates targets in the cytosol
0.0 0.9 REACTOME SMAD2 SMAD3 SMAD4 HETEROTRIMER REGULATES TRANSCRIPTION Genes involved in SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription
0.0 0.7 REACTOME CYTOSOLIC TRNA AMINOACYLATION Genes involved in Cytosolic tRNA aminoacylation
0.0 0.2 REACTOME HYALURONAN UPTAKE AND DEGRADATION Genes involved in Hyaluronan uptake and degradation
0.0 0.5 REACTOME PYRIMIDINE METABOLISM Genes involved in Pyrimidine metabolism
0.0 0.2 REACTOME SIGNALING BY BMP Genes involved in Signaling by BMP
0.0 0.3 REACTOME INTRINSIC PATHWAY Genes involved in Intrinsic Pathway
0.0 0.6 REACTOME EXTENSION OF TELOMERES Genes involved in Extension of Telomeres
0.0 0.1 REACTOME DOWNREGULATION OF SMAD2 3 SMAD4 TRANSCRIPTIONAL ACTIVITY Genes involved in Downregulation of SMAD2/3:SMAD4 transcriptional activity
0.0 0.4 REACTOME SPHINGOLIPID DE NOVO BIOSYNTHESIS Genes involved in Sphingolipid de novo biosynthesis
0.0 0.4 REACTOME PREFOLDIN MEDIATED TRANSFER OF SUBSTRATE TO CCT TRIC Genes involved in Prefoldin mediated transfer of substrate to CCT/TriC
0.0 0.3 REACTOME SIGNALING BY FGFR1 FUSION MUTANTS Genes involved in Signaling by FGFR1 fusion mutants
0.0 0.9 REACTOME MITOTIC PROMETAPHASE Genes involved in Mitotic Prometaphase
0.0 0.3 REACTOME ELONGATION ARREST AND RECOVERY Genes involved in Elongation arrest and recovery