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PRJNA195909:zebrafish embryo and larva development

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Results for myb+mybl1

Z-value: 2.11

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Transcription factors associated with myb+mybl1

Gene Symbol Gene ID Gene Info
ENSDARG00000030999 v-myb avian myeloblastosis viral oncogene homolog-like 1
ENSDARG00000053666 v-myb avian myeloblastosis viral oncogene homolog
ENSDARG00000114024 v-myb avian myeloblastosis viral oncogene homolog

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
mybdr11_v1_chr23_+_31815423_31815492-0.891.5e-03Click!
mybl1dr11_v1_chr24_+_23791758_23791839-0.771.5e-02Click!

Activity profile of myb+mybl1 motif

Sorted Z-values of myb+mybl1 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr6_-_50685862 3.62 ENSDART00000134146
metastasis suppressor 1
chr14_+_15155684 3.14 ENSDART00000167966
zgc:158852
chr19_-_27827744 2.85 ENSDART00000181620
PAP associated domain containing 7
chr8_+_23034718 2.82 ENSDART00000184512
YTH N(6)-methyladenosine RNA binding protein 1
chr12_-_10508952 2.71 ENSDART00000152806
zgc:152977
chr22_-_25612680 2.67 ENSDART00000114167
si:ch211-12h2.8
chr19_+_10661520 2.61 ENSDART00000091813
ENSDART00000165653
argonaute RISC catalytic component 3b
chr5_+_20257225 2.15 ENSDART00000127919
slingshot protein phosphatase 1a
chr10_+_11038192 2.13 ENSDART00000047954
UDP-glucose ceramide glucosyltransferase
chr16_-_27566552 2.09 ENSDART00000142102
zgc:153215
chr11_-_13341051 2.07 ENSDART00000121872
microtubule associated serine/threonine kinase 3b
chr25_-_37262220 1.96 ENSDART00000153789
ENSDART00000155182
ring finger and WD repeat domain 3
chr21_+_12036238 1.95 ENSDART00000102463
ENSDART00000155426
zgc:162344
chr14_-_7409364 1.95 ENSDART00000036463
DND microRNA-mediated repression inhibitor 1
chr3_+_29469283 1.93 ENSDART00000103592
family with sequence similarity 83, member Fa
chr23_-_32390742 1.92 ENSDART00000032861
ankyrin repeat domain 52a
chr2_-_7800702 1.89 ENSDART00000146360
transducin (beta)-like 1 X-linked receptor 1b
chr8_-_14609284 1.87 ENSDART00000146175
centrosomal protein 350
chr10_-_35257458 1.81 ENSDART00000143890
ENSDART00000139107
ENSDART00000082445
proline rich 11
chr23_+_4348479 1.80 ENSDART00000182425
v-myb avian myeloblastosis viral oncogene homolog-like 2a
chr11_+_13176568 1.80 ENSDART00000125371
ENSDART00000123257
MAP kinase interacting serine/threonine kinase 1
chr1_+_51537250 1.79 ENSDART00000152789
ETAA1, ATR kinase activator
chr23_+_4348265 1.77 ENSDART00000136287
v-myb avian myeloblastosis viral oncogene homolog-like 2a
chr11_-_13341483 1.77 ENSDART00000164978
microtubule associated serine/threonine kinase 3b
chr3_+_53156813 1.75 ENSDART00000114343
bromodomain containing 4
chr17_+_21817859 1.74 ENSDART00000143832
ENSDART00000141462
IKAROS family zinc finger 5
chr21_+_43178831 1.73 ENSDART00000151512
AF4/FMR2 family, member 4
chr15_+_22394074 1.71 ENSDART00000109931
OAF homolog a (Drosophila)
chr2_+_30969029 1.70 ENSDART00000085242
lipin 2
chr22_-_38274995 1.70 ENSDART00000179786
ELAV like neuron-specific RNA binding protein 2
chr21_+_4256291 1.68 ENSDART00000148138
leucine rich repeat containing 8 VRAC subunit Aa
chr15_+_29393519 1.65 ENSDART00000193488
ENSDART00000112375
glycerophosphodiester phosphodiesterase domain containing 5b
chr12_-_24832297 1.62 ENSDART00000066317
forkhead box N2b
chr16_-_40459104 1.61 ENSDART00000032389
pleckstrin homology domain containing, family F (with FYVE domain) member 2
chr23_+_27782071 1.61 ENSDART00000131379
lysine (K)-specific methyltransferase 2D
chr13_+_50778187 1.59 ENSDART00000159597
deoxynucleotidyltransferase, terminal
chr16_+_33992418 1.59 ENSDART00000101885
ENSDART00000130540
zinc finger, DHHC-type containing 18a
chr23_+_39963599 1.59 ENSDART00000166539
FYVE and coiled-coil domain containing 1a
chr7_-_16195144 1.58 ENSDART00000173492
bloodthirsty-related gene family, member 4
chr22_-_38274188 1.57 ENSDART00000139420
ENSDART00000015117
ELAV like neuron-specific RNA binding protein 2
chr12_-_628024 1.53 ENSDART00000158563
ENSDART00000152612
wu:fj29h11
si:ch73-301j1.1
chr10_-_35248502 1.53 ENSDART00000087477
SMG8 nonsense mediated mRNA decay factor
chr1_-_53684005 1.52 ENSDART00000108906
exportin 1 (CRM1 homolog, yeast) a
chr17_+_49637257 1.49 ENSDART00000075281
ENSDART00000065917
ENSDART00000123641
zgc:113372
chr4_-_36791395 1.49 ENSDART00000162654
si:dkeyp-87d1.1
chr20_-_18794789 1.47 ENSDART00000003834
cerebral cavernous malformation 2
chr9_-_30808073 1.42 ENSDART00000146300
Kruppel-like factor 5b
chr5_-_18962794 1.42 ENSDART00000145210
ankyrin repeat and LEM domain containing 2
chr19_-_35450857 1.40 ENSDART00000179357
anillin, actin binding protein
chr5_-_66749535 1.39 ENSDART00000132183
K(lysine) acetyltransferase 5b
chr13_-_45063686 1.39 ENSDART00000130467
ENSDART00000136679
calcineurin-like EF-hand protein 1
chr12_+_11650146 1.38 ENSDART00000150191
WAPL cohesin release factor b
chr8_-_4097722 1.38 ENSDART00000135006
cut-like homeobox 2b
chr8_-_14080534 1.38 ENSDART00000042867
death effector domain containing
chr13_+_23104134 1.38 ENSDART00000110266
phosphoinositide-3-kinase adaptor protein 1
chr22_-_8174244 1.38 ENSDART00000156571
si:ch73-44m9.3
chr10_+_2234283 1.37 ENSDART00000136363
contactin associated protein like 3
chr6_-_24392909 1.37 ENSDART00000171042
ENSDART00000168355
bromodomain, testis-specific
chr14_+_21828993 1.36 ENSDART00000144367
C-terminal binding protein 1
chr3_+_17456428 1.36 ENSDART00000090676
ENSDART00000182082
si:ch211-210g13.5
chr16_-_42151909 1.35 ENSDART00000160950
dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1B
chr22_+_15973122 1.35 ENSDART00000144545
ring finger and CCCH-type domains 1a
chr13_+_46718518 1.35 ENSDART00000160401
ENSDART00000182884
transmembrane protein 63Ba
chr4_-_39111612 1.34 ENSDART00000150394
si:dkey-122c11.8
chr21_-_2185004 1.33 ENSDART00000163405
zgc:171220
chr6_+_33931740 1.33 ENSDART00000130492
ENSDART00000151213
origin recognition complex, subunit 1
chr17_-_5610514 1.33 ENSDART00000004043
ectonucleotide pyrophosphatase/phosphodiesterase 4
chr17_-_29249258 1.31 ENSDART00000031458
TNF receptor-associated factor 3
chr15_-_16946124 1.30 ENSDART00000154923
huntingtin interacting protein 1
chr1_+_44540293 1.29 ENSDART00000003497
ENSDART00000179698
zinc finger, DHHC-type containing 5a
chr24_+_21174851 1.28 ENSDART00000154940
ENSDART00000155977
ENSDART00000122762
N(alpha)-acetyltransferase 50, NatE catalytic subunit
chr20_+_33744065 1.28 ENSDART00000015000
HEN methyltransferase 1
chr15_-_23942861 1.28 ENSDART00000002824
amyloid beta precursor protein (cytoplasmic tail) binding protein 2
chr20_-_3390406 1.28 ENSDART00000136987
REV3-like, polymerase (DNA directed), zeta, catalytic subunit
chr1_+_7414318 1.28 ENSDART00000127426
si:ch73-383l1.1
chr11_-_26590401 1.27 ENSDART00000154349
ENSDART00000123094
ST3 beta-galactoside alpha-2,3-sialyltransferase 8
chr12_-_17592215 1.26 ENSDART00000134597
ubiquitin specific peptidase 42
chr18_-_15551360 1.25 ENSDART00000159915
ENSDART00000172690
PTPRF interacting protein, binding protein 1b (liprin beta 1)
chr8_+_23726244 1.25 ENSDART00000132734
makorin, ring finger protein, 4
chr17_+_21818093 1.23 ENSDART00000125335
IKAROS family zinc finger 5
chr21_-_38717854 1.23 ENSDART00000065169
ENSDART00000113813
seven in absentia homolog 2 (Drosophila)-like
chr21_+_19418563 1.22 ENSDART00000181113
ENSDART00000080110
alpha-methylacyl-CoA racemase
chr17_+_46387086 1.22 ENSDART00000157079
si:dkey-206p8.1
chr15_-_26887028 1.21 ENSDART00000156292
si:dkey-243i1.1
chr7_+_38962207 1.20 ENSDART00000173565
diacylglycerol kinase, zeta a
chr16_-_8120203 1.20 ENSDART00000193430
SNF related kinase a
chr22_+_20710434 1.20 ENSDART00000135521
PEAK family member 3
chr24_-_28229618 1.19 ENSDART00000145290
BCL2, apoptosis regulator a
chr5_+_25304499 1.17 ENSDART00000163425
carnosine N-methyltransferase 1
chr5_-_36597612 1.16 ENSDART00000031270
ENSDART00000122098
ras homolog gene family, member Gc
chr2_+_30481125 1.15 ENSDART00000125933
family with sequence similarity 173, member B
chr19_+_38167468 1.15 ENSDART00000160756
PHD finger protein 14
chr13_+_1132261 1.15 ENSDART00000146049
WD repeat domain 92
chr10_-_6588793 1.13 ENSDART00000163788
chromodomain helicase DNA binding protein 1
chr20_-_31743817 1.12 ENSDART00000137679
SAM and SH3 domain containing 1a
chr6_-_24392426 1.12 ENSDART00000163965
bromodomain, testis-specific
chr4_-_7811925 1.11 ENSDART00000103070
cyclin-dependent kinase 17
chr22_-_22164338 1.10 ENSDART00000183840
cell division cycle 34 homolog (S. cerevisiae) a
chr1_+_41596099 1.10 ENSDART00000111367
si:dkey-56e3.3
chr16_-_42152145 1.08 ENSDART00000038748
dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1B
chr7_-_4461104 1.08 ENSDART00000023090
ENSDART00000140770
solute carrier family 12 (sodium/potassium/chloride transporters), member 10, tandem duplicate 1
chr15_-_25319663 1.08 ENSDART00000042218
platelet-activating factor acetylhydrolase 1b, regulatory subunit 1a
chr21_+_33249478 1.08 ENSDART00000169972
si:ch211-151g22.1
chr10_-_28117740 1.07 ENSDART00000134491
mediator complex subunit 13a
chr19_-_35450661 1.07 ENSDART00000113574
ENSDART00000136895
anillin, actin binding protein
chr6_-_39518489 1.06 ENSDART00000185446
activating transcription factor 1
chr9_+_44397151 1.06 ENSDART00000185947
sperm specific antigen 2
chr1_-_53880639 1.06 ENSDART00000010543
LTV1 ribosome biogenesis factor
chr11_-_25461336 1.06 ENSDART00000014945
host cell factor C1a
chr22_-_37738203 1.05 ENSDART00000143190
ArfGAP with coiled-coil, ankyrin repeat and PH domains 2
chr12_-_26538823 1.04 ENSDART00000143213
acyl-CoA synthetase family member 2
chr6_+_40832635 1.04 ENSDART00000011931
RuvB-like AAA ATPase 1
chr9_-_31915423 1.03 ENSDART00000060051
fibroblast growth factor 14
chr12_+_17436904 1.03 ENSDART00000079130
ATPase family, AAA domain containing 1b
chr24_+_24285751 1.02 ENSDART00000122294
YTH N(6)-methyladenosine RNA binding protein 3
chr19_-_47832853 1.02 ENSDART00000170988
argonaute RISC catalytic component 4
chr16_-_13388821 1.02 ENSDART00000144062
glutamate receptor, ionotropic, N-methyl D-aspartate 2D, b
chr14_+_48982236 1.02 ENSDART00000093232
cleavage and polyadenylation factor I subunit 1
chr8_-_25569920 1.01 ENSDART00000136869
phosphatidylinositol-3,4,5-trisphosphate-dependent Rac exchange factor 1
chr3_+_43086548 1.01 ENSDART00000163579
si:dkey-43p13.5
chr22_-_22259175 1.01 ENSDART00000113824
HDGF like 2
chr15_-_25094026 1.01 ENSDART00000129154
exonuclease 5
chr25_+_27744293 1.00 ENSDART00000103519
ENSDART00000149456
Wiskott-Aldrich syndrome-like a
chr19_-_41991104 1.00 ENSDART00000087055
trio Rho guanine nucleotide exchange factor a
chr5_-_61588998 1.00 ENSDART00000050912
peroxisomal biogenesis factor 12
chr25_-_20666328 0.99 ENSDART00000098076
C-terminal Src kinase
chr10_-_18468385 0.99 ENSDART00000183302
si:dkey-28o19.1
chr23_+_24589633 0.99 ENSDART00000143694
mutL homolog 3 (E. coli)
chr25_-_34740627 0.98 ENSDART00000137665
fibroblast growth factor receptor substrate 2b
chr3_-_8542577 0.98 ENSDART00000183527
RNA binding fox-1 homolog 3b
chr8_+_21254192 0.98 ENSDART00000167718
inositol 1,4,5-trisphosphate receptor, type 3
chr8_-_47329755 0.97 ENSDART00000060853
peroxisomal biogenesis factor 10
chr22_+_10232527 0.97 ENSDART00000139297
si:dkeyp-87e7.4
chr17_-_11418513 0.97 ENSDART00000064412
ENSDART00000151847
AT rich interactive domain 4A (RBP1-like)
chr1_+_18863060 0.96 ENSDART00000139241
ring finger protein 38
chr18_-_29972709 0.96 ENSDART00000131207
si:ch211-220f16.2
chr10_+_35257651 0.95 ENSDART00000028940
serine/threonine/tyrosine interacting-like 1
chr4_+_5318901 0.95 ENSDART00000067378
si:ch211-214j24.10
chr13_+_1131748 0.95 ENSDART00000054318
WD repeat domain 92
chr13_+_18471546 0.94 ENSDART00000090712
ENSDART00000127962
storkhead box 1
chr24_-_41180149 0.94 ENSDART00000019975
activin A receptor type 2Ba
chr15_-_25093680 0.94 ENSDART00000062695
exonuclease 5
chr1_+_6206950 0.93 ENSDART00000146473
reticulophagy regulator family member 2
chr19_-_1002959 0.93 ENSDART00000168138
euchromatic histone-lysine N-methyltransferase 2
chr14_+_15484544 0.93 ENSDART00000188649

chr8_-_11004726 0.93 ENSDART00000192594
ENSDART00000020116
tripartite motif containing 33
chr17_+_23729717 0.92 ENSDART00000179026
zgc:91976
chr18_+_39106722 0.92 ENSDART00000122377
BCL2 like 10
chr14_-_30905288 0.92 ENSDART00000173449
ENSDART00000173451
si:ch211-126c2.4
chr7_+_56253914 0.92 ENSDART00000073594
ankyrin repeat domain 11
chr21_-_31013817 0.92 ENSDART00000065504
nuclear cap binding subunit 3
chr24_+_21174523 0.91 ENSDART00000183849
N(alpha)-acetyltransferase 50, NatE catalytic subunit
chr1_+_19434198 0.91 ENSDART00000012552
clock circadian regulator b
chr17_-_11417904 0.91 ENSDART00000103228
AT rich interactive domain 4A (RBP1-like)
chr6_+_58280936 0.90 ENSDART00000155244
Ral GTPase activating protein, beta subunit (non-catalytic)
chr13_-_5257303 0.90 ENSDART00000110610
si:dkey-78p8.1
chr7_+_30933867 0.89 ENSDART00000156325
tight junction protein 1a
chr14_-_33177935 0.88 ENSDART00000180583
ENSDART00000078856
discs, large homolog 3 (Drosophila)
chr16_-_4531657 0.88 ENSDART00000028419
protein phosphatase 1, regulatory subunit 8b
chr6_-_24053404 0.87 ENSDART00000168511
si:dkey-44g17.6
chr22_-_9860792 0.86 ENSDART00000155908
si:dkey-253d23.2
chr6_-_57539141 0.86 ENSDART00000156967
itchy E3 ubiquitin protein ligase a
chr14_-_33081784 0.86 ENSDART00000165726
discs, large homolog 3 (Drosophila)
chr7_+_7151832 0.86 ENSDART00000109485
galactose-3-O-sulfotransferase 3
chr7_-_12464412 0.86 ENSDART00000178723
ADAMTS-like 3
chr24_-_25673405 0.84 ENSDART00000186081
ENSDART00000110241
ENSDART00000142351
connector enhancer of kinase suppressor of Ras 2a
chr13_-_49144799 0.83 ENSDART00000030939
ENSDART00000148922
disrupted in schizophrenia 1
chr5_-_39805874 0.83 ENSDART00000176202
ENSDART00000191683
RasGEF domain family, member 1Ba
chr5_+_44064764 0.83 ENSDART00000143843
si:dkey-84j12.1
chr3_+_37649436 0.83 ENSDART00000075039
golgi SNAP receptor complex member 2
chr1_+_604127 0.82 ENSDART00000133165
junctional adhesion molecule 2a
chr15_-_36249087 0.82 ENSDART00000157190
osteocrin
chr11_-_574423 0.82 ENSDART00000176364
ENSDART00000130504
makorin, ring finger protein, 2
chr14_+_30775066 0.82 ENSDART00000139975
ENSDART00000144921
atlastin 3
chr19_-_25149034 0.81 ENSDART00000148432
ENSDART00000175266
protein tyrosine phosphatase type IVA, member 3
chr14_+_6535426 0.80 ENSDART00000055961
tRNA-histidine guanylyltransferase 1-like
chr15_+_11825366 0.80 ENSDART00000190042
protein kinase D2
chr4_-_72609118 0.80 ENSDART00000174077
si:cabz01054396.2
chr23_+_32029304 0.79 ENSDART00000185217
TPX2, microtubule-associated, homolog (Xenopus laevis)
chr8_-_52230115 0.79 ENSDART00000157890
ENSDART00000148760
transcription factor 7 like 1b
chr2_+_46032678 0.79 ENSDART00000184382
ENSDART00000125971
glypican 1b
chr2_-_38261272 0.79 ENSDART00000143743
si:ch211-14a17.10
chr3_+_31717291 0.78 ENSDART00000058221
ddb1 and cul4 associated factor 7
chr20_+_22799857 0.78 ENSDART00000058527
sec1 family domain containing 2
chr7_-_6415991 0.78 ENSDART00000173349
Histone H3.2
chr23_-_18568522 0.77 ENSDART00000004655
selenophosphate synthetase 2
chr13_+_23093743 0.77 ENSDART00000148034
phosphoinositide-3-kinase adaptor protein 1
chr7_-_49646251 0.77 ENSDART00000193674
-Ha-ras Harvey rat sarcoma viral oncogene homolog b
chr7_+_24393678 0.77 ENSDART00000188690
HAUS augmin-like complex, subunit 3
chr7_+_30202104 0.77 ENSDART00000173525
WD repeat domain 76
chr15_+_4988189 0.76 ENSDART00000142995
ENSDART00000062852
signal peptidase complex subunit 2
chr14_-_246342 0.76 ENSDART00000054823
aurora kinase B
chr6_+_33885828 0.76 ENSDART00000179994
GC-rich promoter binding protein 1-like 1
chr8_+_18555559 0.76 ENSDART00000149523
TGF-beta activated kinase 1/MAP3K7 binding protein 3
chr13_-_38039871 0.76 ENSDART00000140645

chr19_+_38168006 0.75 ENSDART00000087662
ENSDART00000177759
PHD finger protein 14
chr23_+_36616717 0.74 ENSDART00000042701
ENSDART00000192980
phosphatidylinositol-5-phosphate 4-kinase, type II, gamma a
chr17_-_22573311 0.74 ENSDART00000141523
ENSDART00000140022
ENSDART00000079390
ENSDART00000188644
exonuclease 1
chr9_+_56443416 0.73 ENSDART00000167947

chr19_+_4068134 0.73 ENSDART00000158285
bloodthirsty-related gene family, member 26

Network of associatons between targets according to the STRING database.

First level regulatory network of myb+mybl1

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.8 2.5 GO:0051037 histone displacement(GO:0001207) regulation of transcription involved in meiotic cell cycle(GO:0051037) positive regulation of transcription involved in meiotic cell cycle(GO:0051039)
0.7 2.1 GO:0006678 glucosylceramide metabolic process(GO:0006678)
0.7 3.5 GO:2000001 regulation of DNA damage checkpoint(GO:2000001)
0.6 2.5 GO:0008356 asymmetric cell division(GO:0008356)
0.6 3.0 GO:0071908 determination of intestine left/right asymmetry(GO:0071908)
0.6 1.7 GO:1901407 regulation of phosphorylation of RNA polymerase II C-terminal domain(GO:1901407)
0.5 2.2 GO:0034087 establishment of mitotic sister chromatid cohesion(GO:0034087) mitotic sister chromatid cohesion, centromeric(GO:0071962)
0.5 1.4 GO:0060623 regulation of chromosome condensation(GO:0060623)
0.4 1.2 GO:0090004 positive regulation of Golgi to plasma membrane protein transport(GO:0042998) positive regulation of establishment of protein localization to plasma membrane(GO:0090004)
0.3 2.0 GO:0060149 negative regulation of posttranscriptional gene silencing(GO:0060149) negative regulation of gene silencing by miRNA(GO:0060965) negative regulation of gene silencing by RNA(GO:0060967)
0.3 3.8 GO:0050779 RNA destabilization(GO:0050779) mRNA destabilization(GO:0061157)
0.3 2.9 GO:0000056 ribosomal small subunit export from nucleus(GO:0000056)
0.3 1.6 GO:1901098 positive regulation of autophagosome maturation(GO:1901098)
0.3 3.0 GO:0016246 RNA interference(GO:0016246)
0.3 1.4 GO:0010456 cell proliferation in dorsal spinal cord(GO:0010456)
0.3 1.1 GO:0051012 microtubule sliding(GO:0051012)
0.3 2.6 GO:0072091 regulation of stem cell proliferation(GO:0072091)
0.3 0.8 GO:0002902 B cell apoptotic process(GO:0001783) regulation of B cell apoptotic process(GO:0002902) regulation of lymphocyte apoptotic process(GO:0070228)
0.2 1.0 GO:2001244 positive regulation of intrinsic apoptotic signaling pathway(GO:2001244)
0.2 0.7 GO:0019264 glycine biosynthetic process from serine(GO:0019264)
0.2 0.8 GO:0021755 eurydendroid cell differentiation(GO:0021755)
0.2 1.8 GO:0000083 regulation of transcription involved in G1/S transition of mitotic cell cycle(GO:0000083)
0.2 1.0 GO:0060368 Fc receptor mediated stimulatory signaling pathway(GO:0002431) regulation of Fc receptor mediated stimulatory signaling pathway(GO:0060368)
0.2 1.3 GO:1900048 positive regulation of blood coagulation(GO:0030194) positive regulation of coagulation(GO:0050820) positive regulation of hemostasis(GO:1900048)
0.2 0.6 GO:0006451 selenocysteine incorporation(GO:0001514) translational readthrough(GO:0006451)
0.2 0.9 GO:0008635 activation of cysteine-type endopeptidase activity involved in apoptotic process by cytochrome c(GO:0008635)
0.2 1.3 GO:0008063 Toll signaling pathway(GO:0008063)
0.2 0.9 GO:0006370 7-methylguanosine mRNA capping(GO:0006370)
0.2 0.7 GO:0016267 O-glycan processing, core 1(GO:0016267)
0.2 0.4 GO:0043504 mitochondrial DNA repair(GO:0043504)
0.2 1.6 GO:0003428 growth plate cartilage morphogenesis(GO:0003422) chondrocyte intercalation involved in growth plate cartilage morphogenesis(GO:0003428)
0.2 0.7 GO:0006116 NADH oxidation(GO:0006116) glycerol-3-phosphate catabolic process(GO:0046168)
0.2 1.3 GO:0033314 mitotic DNA replication checkpoint(GO:0033314)
0.2 0.5 GO:0019284 L-methionine biosynthetic process from S-adenosylmethionine(GO:0019284)
0.2 1.4 GO:0007084 mitotic nuclear envelope reassembly(GO:0007084)
0.2 0.9 GO:0051570 regulation of histone H3-K9 methylation(GO:0051570)
0.1 1.0 GO:0060420 box C/D snoRNP assembly(GO:0000492) regulation of heart growth(GO:0060420)
0.1 0.4 GO:0006290 somatic diversification of immune receptors via somatic mutation(GO:0002566) pyrimidine dimer repair(GO:0006290) somatic hypermutation of immunoglobulin genes(GO:0016446)
0.1 1.3 GO:0042276 error-prone translesion synthesis(GO:0042276)
0.1 4.3 GO:0036297 interstrand cross-link repair(GO:0036297)
0.1 1.9 GO:0044154 histone H3-K14 acetylation(GO:0044154)
0.1 0.8 GO:0089700 endocardial cushion formation(GO:0003272) protein kinase D signaling(GO:0089700)
0.1 0.4 GO:0000212 meiotic spindle organization(GO:0000212)
0.1 0.5 GO:0010610 regulation of mRNA stability involved in response to stress(GO:0010610) regulation of mRNA stability involved in response to oxidative stress(GO:2000815)
0.1 0.4 GO:0038158 granulocyte colony-stimulating factor signaling pathway(GO:0038158)
0.1 0.9 GO:0048569 post-embryonic organ development(GO:0048569)
0.1 0.3 GO:0003161 cardiac conduction system development(GO:0003161)
0.1 0.9 GO:0006686 sphingomyelin biosynthetic process(GO:0006686)
0.1 0.5 GO:0016332 establishment or maintenance of polarity of embryonic epithelium(GO:0016332)
0.1 0.6 GO:0007221 positive regulation of transcription of Notch receptor target(GO:0007221)
0.1 2.0 GO:0016558 protein import into peroxisome matrix(GO:0016558)
0.1 1.4 GO:0008625 extrinsic apoptotic signaling pathway via death domain receptors(GO:0008625)
0.1 2.8 GO:0006998 nuclear envelope organization(GO:0006998)
0.1 0.5 GO:0097039 protein linear polyubiquitination(GO:0097039)
0.1 0.4 GO:0034723 DNA replication-dependent nucleosome assembly(GO:0006335) DNA replication-dependent nucleosome organization(GO:0034723)
0.1 0.5 GO:0060231 mesenchymal to epithelial transition(GO:0060231)
0.1 0.5 GO:1904292 regulation of ERAD pathway(GO:1904292)
0.1 0.9 GO:0051279 regulation of calcium ion transport into cytosol(GO:0010522) regulation of release of sequestered calcium ion into cytosol(GO:0051279)
0.1 0.8 GO:0048280 vesicle fusion with Golgi apparatus(GO:0048280)
0.1 0.8 GO:0001958 endochondral ossification(GO:0001958) replacement ossification(GO:0036075)
0.1 0.5 GO:0098529 neuromuscular junction development, skeletal muscle fiber(GO:0098529)
0.1 1.9 GO:0034453 microtubule anchoring(GO:0034453)
0.1 1.7 GO:0060079 excitatory postsynaptic potential(GO:0060079)
0.1 0.8 GO:0006465 signal peptide processing(GO:0006465)
0.1 0.9 GO:0036060 filtration diaphragm assembly(GO:0036058) slit diaphragm assembly(GO:0036060)
0.1 0.4 GO:0007618 mating(GO:0007618)
0.1 1.2 GO:0043154 negative regulation of cysteine-type endopeptidase activity involved in apoptotic process(GO:0043154)
0.1 1.8 GO:0007205 protein kinase C-activating G-protein coupled receptor signaling pathway(GO:0007205)
0.1 1.6 GO:0043252 sodium-independent organic anion transport(GO:0043252)
0.1 0.6 GO:0051673 membrane disruption in other organism(GO:0051673)
0.1 0.4 GO:0000738 DNA catabolic process, exonucleolytic(GO:0000738)
0.1 1.7 GO:0006298 mismatch repair(GO:0006298)
0.1 0.4 GO:0090520 sphingolipid mediated signaling pathway(GO:0090520)
0.1 0.7 GO:0070475 rRNA base methylation(GO:0070475)
0.1 1.0 GO:1905150 regulation of voltage-gated sodium channel activity(GO:1905150)
0.1 1.0 GO:0035278 miRNA mediated inhibition of translation(GO:0035278) negative regulation of translation, ncRNA-mediated(GO:0040033) regulation of translation, ncRNA-mediated(GO:0045974)
0.1 0.3 GO:0007250 activation of NF-kappaB-inducing kinase activity(GO:0007250)
0.1 0.4 GO:0070086 ubiquitin-dependent endocytosis(GO:0070086)
0.1 0.6 GO:0031954 positive regulation of protein autophosphorylation(GO:0031954)
0.1 1.1 GO:0021979 hypothalamus cell differentiation(GO:0021979)
0.1 0.3 GO:0035434 copper ion transmembrane transport(GO:0035434)
0.1 0.6 GO:0060386 synapse assembly involved in innervation(GO:0060386)
0.1 1.0 GO:2000601 positive regulation of actin nucleation(GO:0051127) positive regulation of Arp2/3 complex-mediated actin nucleation(GO:2000601)
0.1 1.6 GO:0006303 double-strand break repair via nonhomologous end joining(GO:0006303)
0.1 0.2 GO:0030970 retrograde protein transport, ER to cytosol(GO:0030970) endoplasmic reticulum to cytosol transport(GO:1903513)
0.1 1.9 GO:0048268 clathrin coat assembly(GO:0048268)
0.1 0.6 GO:0006685 sphingomyelin catabolic process(GO:0006685)
0.1 0.8 GO:0060236 regulation of mitotic spindle organization(GO:0060236)
0.1 0.7 GO:0031952 regulation of protein autophosphorylation(GO:0031952)
0.1 0.3 GO:2000582 positive regulation of microtubule motor activity(GO:2000576) regulation of ATP-dependent microtubule motor activity, plus-end-directed(GO:2000580) positive regulation of ATP-dependent microtubule motor activity, plus-end-directed(GO:2000582)
0.1 2.3 GO:0097120 receptor localization to synapse(GO:0097120)
0.1 1.1 GO:0006904 vesicle docking involved in exocytosis(GO:0006904)
0.1 0.4 GO:0034389 lipid particle organization(GO:0034389)
0.1 1.5 GO:0000184 nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:0000184)
0.1 2.7 GO:0018345 protein palmitoylation(GO:0018345)
0.0 0.4 GO:0006751 glutathione catabolic process(GO:0006751)
0.0 0.7 GO:0016199 axon midline choice point recognition(GO:0016199)
0.0 3.1 GO:0018107 peptidyl-threonine phosphorylation(GO:0018107)
0.0 1.0 GO:0051209 release of sequestered calcium ion into cytosol(GO:0051209)
0.0 2.0 GO:0032924 activin receptor signaling pathway(GO:0032924)
0.0 0.2 GO:0051898 negative regulation of protein kinase B signaling(GO:0051898)
0.0 1.8 GO:0000288 nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay(GO:0000288)
0.0 1.1 GO:0006884 cell volume homeostasis(GO:0006884)
0.0 1.2 GO:0016601 Rac protein signal transduction(GO:0016601)
0.0 1.2 GO:0007099 centriole replication(GO:0007099)
0.0 0.2 GO:1902269 polyamine transport(GO:0015846) polyamine transmembrane transport(GO:1902047) regulation of polyamine transmembrane transport(GO:1902267) positive regulation of polyamine transmembrane transport(GO:1902269)
0.0 1.8 GO:0007050 cell cycle arrest(GO:0007050)
0.0 2.4 GO:0007528 neuromuscular junction development(GO:0007528)
0.0 0.6 GO:0050910 detection of mechanical stimulus involved in sensory perception of sound(GO:0050910)
0.0 0.4 GO:0046548 retinal rod cell development(GO:0046548)
0.0 0.2 GO:0042249 establishment of planar polarity of embryonic epithelium(GO:0042249) establishment of planar polarity involved in neural tube closure(GO:0090177) regulation of establishment of planar polarity involved in neural tube closure(GO:0090178) planar cell polarity pathway involved in neural tube closure(GO:0090179)
0.0 0.9 GO:0035305 negative regulation of dephosphorylation(GO:0035305) negative regulation of protein dephosphorylation(GO:0035308)
0.0 5.5 GO:0018105 peptidyl-serine phosphorylation(GO:0018105)
0.0 0.2 GO:0070973 protein localization to endoplasmic reticulum exit site(GO:0070973)
0.0 0.7 GO:0097194 execution phase of apoptosis(GO:0097194)
0.0 0.6 GO:0030277 maintenance of gastrointestinal epithelium(GO:0030277) intestinal epithelial structure maintenance(GO:0060729)
0.0 0.9 GO:0009247 glycolipid biosynthetic process(GO:0009247)
0.0 0.6 GO:0070936 protein K48-linked ubiquitination(GO:0070936)
0.0 0.9 GO:0009648 photoperiodism(GO:0009648)
0.0 1.2 GO:0043123 positive regulation of I-kappaB kinase/NF-kappaB signaling(GO:0043123)
0.0 0.3 GO:0030241 skeletal muscle myosin thick filament assembly(GO:0030241)
0.0 1.4 GO:0009948 anterior/posterior axis specification(GO:0009948)
0.0 1.7 GO:0009062 fatty acid catabolic process(GO:0009062)
0.0 0.2 GO:0090505 wound healing, spreading of cells(GO:0044319) epiboly involved in wound healing(GO:0090505) skeletal muscle satellite cell migration(GO:1902766)
0.0 0.8 GO:0040037 negative regulation of fibroblast growth factor receptor signaling pathway(GO:0040037)
0.0 1.9 GO:0048015 phosphatidylinositol-mediated signaling(GO:0048015)
0.0 1.0 GO:0048384 retinoic acid receptor signaling pathway(GO:0048384)
0.0 0.3 GO:0009303 rRNA transcription(GO:0009303)
0.0 0.2 GO:0006283 transcription-coupled nucleotide-excision repair(GO:0006283)
0.0 0.2 GO:0006488 dolichol-linked oligosaccharide biosynthetic process(GO:0006488)
0.0 1.5 GO:0060216 definitive hemopoiesis(GO:0060216)
0.0 0.2 GO:0035066 positive regulation of histone acetylation(GO:0035066)
0.0 0.7 GO:0006661 phosphatidylinositol biosynthetic process(GO:0006661)
0.0 0.3 GO:0086010 membrane depolarization during action potential(GO:0086010)
0.0 0.1 GO:0002753 cytoplasmic pattern recognition receptor signaling pathway(GO:0002753)
0.0 0.6 GO:0016525 negative regulation of angiogenesis(GO:0016525)
0.0 0.8 GO:0007029 endoplasmic reticulum organization(GO:0007029)
0.0 0.2 GO:2000785 regulation of autophagosome assembly(GO:2000785)
0.0 1.0 GO:0048484 enteric nervous system development(GO:0048484)
0.0 1.6 GO:0030837 negative regulation of actin filament polymerization(GO:0030837) negative regulation of protein polymerization(GO:0032272)
0.0 0.3 GO:0046475 glycerophospholipid catabolic process(GO:0046475)
0.0 1.1 GO:0016573 histone acetylation(GO:0016573)
0.0 1.4 GO:0090630 activation of GTPase activity(GO:0090630)
0.0 1.0 GO:0000381 regulation of alternative mRNA splicing, via spliceosome(GO:0000381)
0.0 0.6 GO:0007093 mitotic cell cycle checkpoint(GO:0007093)
0.0 0.2 GO:0018057 peptidyl-lysine oxidation(GO:0018057)
0.0 2.4 GO:0007009 plasma membrane organization(GO:0007009)
0.0 0.5 GO:0051781 positive regulation of cell division(GO:0051781)
0.0 1.4 GO:0016579 protein deubiquitination(GO:0016579)
0.0 0.8 GO:0006400 tRNA modification(GO:0006400)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 2.0 GO:0043073 germ cell nucleus(GO:0043073)
0.5 3.6 GO:0016442 RISC complex(GO:0016442) RNAi effector complex(GO:0031332)
0.4 2.2 GO:0031415 NatA complex(GO:0031415)
0.4 2.5 GO:0005826 actomyosin contractile ring(GO:0005826)
0.3 1.0 GO:1990415 Pex17p-Pex14p docking complex(GO:1990415) peroxisomal importomer complex(GO:1990429)
0.3 1.3 GO:0098890 extrinsic component of postsynaptic membrane(GO:0098890)
0.3 0.8 GO:0098636 protein complex involved in cell adhesion(GO:0098636)
0.3 1.1 GO:0008247 1-alkyl-2-acetylglycerophosphocholine esterase complex(GO:0008247)
0.3 1.0 GO:0097255 R2TP complex(GO:0097255)
0.3 1.0 GO:0000214 tRNA-intron endonuclease complex(GO:0000214)
0.2 1.7 GO:0032783 ELL-EAF complex(GO:0032783)
0.2 0.8 GO:0005880 nuclear microtubule(GO:0005880)
0.2 0.8 GO:0005787 signal peptidase complex(GO:0005787)
0.2 0.9 GO:1990513 CLOCK-BMAL transcription complex(GO:1990513)
0.1 0.4 GO:0032301 MutSalpha complex(GO:0032301)
0.1 2.7 GO:0034993 microtubule organizing center attachment site(GO:0034992) LINC complex(GO:0034993)
0.1 1.0 GO:0032300 mismatch repair complex(GO:0032300)
0.1 0.6 GO:0071439 clathrin complex(GO:0071439)
0.1 0.8 GO:0032133 chromosome passenger complex(GO:0032133)
0.1 1.7 GO:0017146 NMDA selective glutamate receptor complex(GO:0017146)
0.1 0.7 GO:0009331 glycerol-3-phosphate dehydrogenase complex(GO:0009331)
0.1 1.3 GO:0000808 origin recognition complex(GO:0000808) nuclear origin of replication recognition complex(GO:0005664)
0.1 1.9 GO:0070776 H3 histone acetyltransferase complex(GO:0070775) MOZ/MORF histone acetyltransferase complex(GO:0070776)
0.1 2.7 GO:0043596 nuclear replication fork(GO:0043596)
0.1 1.3 GO:0042575 DNA polymerase complex(GO:0042575)
0.1 1.1 GO:0030688 preribosome, small subunit precursor(GO:0030688)
0.1 1.0 GO:0042788 polysomal ribosome(GO:0042788)
0.1 2.0 GO:1990907 beta-catenin-TCF complex(GO:1990907)
0.1 1.8 GO:0009925 basal plasma membrane(GO:0009925)
0.1 1.4 GO:0035267 NuA4 histone acetyltransferase complex(GO:0035267) H4/H2A histone acetyltransferase complex(GO:0043189) H4 histone acetyltransferase complex(GO:1902562)
0.1 0.8 GO:0070652 HAUS complex(GO:0070652)
0.1 1.6 GO:0044666 MLL3/4 complex(GO:0044666)
0.1 1.1 GO:1990589 ATF4-CREB1 transcription factor complex(GO:1990589)
0.1 2.0 GO:0035861 site of double-strand break(GO:0035861)
0.1 0.9 GO:0048179 activin receptor complex(GO:0048179)
0.1 1.1 GO:0048188 Set1C/COMPASS complex(GO:0048188)
0.1 2.1 GO:0010494 cytoplasmic stress granule(GO:0010494)
0.1 0.3 GO:0044611 nuclear pore inner ring(GO:0044611)
0.1 0.4 GO:0070847 core mediator complex(GO:0070847)
0.1 0.5 GO:0071797 LUBAC complex(GO:0071797)
0.1 0.9 GO:0031680 G-protein beta/gamma-subunit complex(GO:0031680)
0.0 1.0 GO:0030667 secretory granule membrane(GO:0030667)
0.0 1.3 GO:0043186 P granule(GO:0043186)
0.0 0.3 GO:0005682 U5 snRNP(GO:0005682)
0.0 0.8 GO:0030867 rough endoplasmic reticulum membrane(GO:0030867)
0.0 0.4 GO:0000930 gamma-tubulin complex(GO:0000930)
0.0 0.5 GO:0031462 Cul2-RING ubiquitin ligase complex(GO:0031462)
0.0 0.5 GO:0001917 photoreceptor inner segment(GO:0001917)
0.0 0.5 GO:0071014 post-mRNA release spliceosomal complex(GO:0071014)
0.0 0.8 GO:0046658 anchored component of plasma membrane(GO:0046658)
0.0 0.2 GO:1990130 Iml1 complex(GO:1990130)
0.0 0.3 GO:0043240 Fanconi anaemia nuclear complex(GO:0043240)
0.0 0.4 GO:0044224 juxtaparanode region of axon(GO:0044224)
0.0 2.3 GO:0098878 ionotropic glutamate receptor complex(GO:0008328) neurotransmitter receptor complex(GO:0098878)
0.0 0.7 GO:0005686 U2 snRNP(GO:0005686)
0.0 0.5 GO:0016581 NuRD complex(GO:0016581) CHD-type complex(GO:0090545)
0.0 0.1 GO:0071005 U2-type precatalytic spliceosome(GO:0071005)
0.0 0.5 GO:1990391 DNA repair complex(GO:1990391)
0.0 0.4 GO:0032391 photoreceptor connecting cilium(GO:0032391)
0.0 1.6 GO:0005776 autophagosome(GO:0005776)
0.0 0.3 GO:0005868 cytoplasmic dynein complex(GO:0005868)
0.0 0.8 GO:0012507 ER to Golgi transport vesicle membrane(GO:0012507)
0.0 1.1 GO:0016592 mediator complex(GO:0016592)
0.0 0.7 GO:0042734 presynaptic membrane(GO:0042734)
0.0 1.9 GO:0048786 presynaptic active zone(GO:0048786)
0.0 0.7 GO:0000159 protein phosphatase type 2A complex(GO:0000159)
0.0 0.6 GO:0071013 catalytic step 2 spliceosome(GO:0071013)
0.0 0.4 GO:0030014 CCR4-NOT complex(GO:0030014)
0.0 1.6 GO:0098802 plasma membrane receptor complex(GO:0098802)
0.0 0.4 GO:0016281 eukaryotic translation initiation factor 4F complex(GO:0016281)
0.0 0.6 GO:0031903 peroxisomal membrane(GO:0005778) microbody membrane(GO:0031903)
0.0 0.1 GO:0044613 nuclear pore central transport channel(GO:0044613)
0.0 1.2 GO:0031965 nuclear membrane(GO:0031965)
0.0 0.9 GO:0042579 peroxisome(GO:0005777) microbody(GO:0042579)
0.0 0.1 GO:0005665 DNA-directed RNA polymerase II, core complex(GO:0005665)
0.0 1.6 GO:0005802 trans-Golgi network(GO:0005802)
0.0 0.3 GO:0034706 voltage-gated sodium channel complex(GO:0001518) sodium channel complex(GO:0034706)
0.0 1.7 GO:0000793 condensed chromosome(GO:0000793)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.9 2.7 GO:0045145 single-stranded DNA 5'-3' exodeoxyribonuclease activity(GO:0045145)
0.6 3.8 GO:1990247 N6-methyladenosine-containing RNA binding(GO:1990247)
0.5 1.5 GO:0047760 medium-chain fatty acid-CoA ligase activity(GO:0031956) butyrate-CoA ligase activity(GO:0047760)
0.4 3.6 GO:0035198 miRNA binding(GO:0035198)
0.3 1.0 GO:0008022 protein C-terminus binding(GO:0008022)
0.3 4.2 GO:0070577 lysine-acetylated histone binding(GO:0070577)
0.3 1.2 GO:0071253 connexin binding(GO:0071253)
0.3 1.0 GO:0046404 ATP-dependent polydeoxyribonucleotide 5'-hydroxyl-kinase activity(GO:0046404) polydeoxyribonucleotide kinase activity(GO:0051733) ATP-dependent polynucleotide kinase activity(GO:0051734)
0.2 2.7 GO:0043495 protein anchor(GO:0043495)
0.2 0.7 GO:0016434 rRNA (cytosine) methyltransferase activity(GO:0016434)
0.2 0.7 GO:0070905 glycine hydroxymethyltransferase activity(GO:0004372) serine binding(GO:0070905)
0.2 2.2 GO:0010485 H4 histone acetyltransferase activity(GO:0010485)
0.2 1.0 GO:0043139 5'-3' DNA helicase activity(GO:0043139)
0.2 1.5 GO:0035173 histone kinase activity(GO:0035173)
0.2 1.4 GO:0035613 RNA stem-loop binding(GO:0035613)
0.2 1.5 GO:0008410 CoA-transferase activity(GO:0008410)
0.2 0.7 GO:0016308 1-phosphatidylinositol-4-phosphate 5-kinase activity(GO:0016308)
0.2 0.7 GO:0016263 glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase activity(GO:0016263) beta-1,3-galactosyltransferase activity(GO:0048531)
0.2 1.8 GO:0005225 volume-sensitive anion channel activity(GO:0005225)
0.2 1.3 GO:0003836 beta-galactoside (CMP) alpha-2,3-sialyltransferase activity(GO:0003836)
0.2 1.8 GO:0005049 nuclear export signal receptor activity(GO:0005049)
0.2 0.7 GO:0032296 ribonuclease III activity(GO:0004525) double-stranded RNA-specific ribonuclease activity(GO:0032296)
0.2 0.7 GO:0004367 glycerol-3-phosphate dehydrogenase [NAD+] activity(GO:0004367)
0.2 2.1 GO:0036312 phosphatidylinositol 3-kinase regulatory subunit binding(GO:0036312)
0.2 2.8 GO:0046527 glucosyltransferase activity(GO:0046527)
0.2 0.9 GO:0047493 sphingomyelin synthase activity(GO:0033188) ceramide cholinephosphotransferase activity(GO:0047493)
0.1 0.4 GO:0017050 D-erythro-sphingosine kinase activity(GO:0017050)
0.1 0.4 GO:0032143 guanine/thymine mispair binding(GO:0032137) single base insertion or deletion binding(GO:0032138) single thymine insertion binding(GO:0032143) oxidized DNA binding(GO:0032356) oxidized purine DNA binding(GO:0032357) mismatch repair complex binding(GO:0032404) MutLalpha complex binding(GO:0032405)
0.1 1.9 GO:0032051 clathrin light chain binding(GO:0032051)
0.1 1.9 GO:0010484 H3 histone acetyltransferase activity(GO:0010484) histone acetyltransferase activity (H3-K23 specific)(GO:0043994)
0.1 0.8 GO:0070568 guanylyltransferase activity(GO:0070568)
0.1 0.9 GO:0070888 E-box binding(GO:0070888)
0.1 2.9 GO:0003887 DNA-directed DNA polymerase activity(GO:0003887)
0.1 1.1 GO:0008511 sodium:potassium:chloride symporter activity(GO:0008511)
0.1 0.5 GO:0004968 gonadotropin-releasing hormone receptor activity(GO:0004968)
0.1 0.4 GO:0003827 alpha-1,3-mannosylglycoprotein 2-beta-N-acetylglucosaminyltransferase activity(GO:0003827)
0.1 0.4 GO:0003839 gamma-glutamylcyclotransferase activity(GO:0003839)
0.1 0.9 GO:0004865 protein serine/threonine phosphatase inhibitor activity(GO:0004865)
0.1 0.9 GO:0050694 galactosylceramide sulfotransferase activity(GO:0001733) galactose 3-O-sulfotransferase activity(GO:0050694)
0.1 1.4 GO:0051721 protein phosphatase 2A binding(GO:0051721)
0.1 0.4 GO:0008297 single-stranded DNA exodeoxyribonuclease activity(GO:0008297)
0.1 1.3 GO:0004551 nucleotide diphosphatase activity(GO:0004551)
0.1 1.3 GO:0000340 RNA 7-methylguanosine cap binding(GO:0000340)
0.1 0.6 GO:1990050 phosphatidic acid transporter activity(GO:1990050)
0.1 2.7 GO:0043539 protein serine/threonine kinase activator activity(GO:0043539)
0.1 1.0 GO:0005220 inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity(GO:0005220)
0.1 3.0 GO:0009931 calcium-dependent protein serine/threonine kinase activity(GO:0009931)
0.1 1.8 GO:0004143 diacylglycerol kinase activity(GO:0004143)
0.1 1.6 GO:0015347 sodium-independent organic anion transmembrane transporter activity(GO:0015347)
0.1 1.1 GO:0070840 dynein complex binding(GO:0070840)
0.1 1.5 GO:0004972 NMDA glutamate receptor activity(GO:0004972)
0.1 1.2 GO:0002039 p53 binding(GO:0002039)
0.1 0.6 GO:0005161 platelet-derived growth factor receptor binding(GO:0005161)
0.1 1.6 GO:0042800 histone methyltransferase activity (H3-K4 specific)(GO:0042800)
0.1 0.3 GO:0005375 copper ion transmembrane transporter activity(GO:0005375)
0.1 2.8 GO:0004712 protein serine/threonine/tyrosine kinase activity(GO:0004712)
0.1 1.0 GO:0030983 mismatched DNA binding(GO:0030983)
0.1 0.5 GO:0032422 purine-rich negative regulatory element binding(GO:0032422)
0.1 0.5 GO:0004430 1-phosphatidylinositol 4-kinase activity(GO:0004430)
0.1 2.7 GO:0019707 protein-cysteine S-palmitoyltransferase activity(GO:0019706) protein-cysteine S-acyltransferase activity(GO:0019707)
0.1 5.9 GO:0003730 mRNA 3'-UTR binding(GO:0003730)
0.1 0.9 GO:0017002 activin-activated receptor activity(GO:0017002)
0.1 1.3 GO:0003688 DNA replication origin binding(GO:0003688)
0.1 1.7 GO:0008195 phosphatidate phosphatase activity(GO:0008195)
0.1 0.9 GO:0008239 dipeptidyl-peptidase activity(GO:0008239)
0.0 1.3 GO:0008171 O-methyltransferase activity(GO:0008171)
0.0 1.6 GO:0005164 tumor necrosis factor receptor binding(GO:0005164)
0.0 1.3 GO:0004402 histone acetyltransferase activity(GO:0004402)
0.0 1.4 GO:0005227 calcium activated cation channel activity(GO:0005227)
0.0 1.1 GO:0005154 epidermal growth factor receptor binding(GO:0005154)
0.0 0.3 GO:0008332 low voltage-gated calcium channel activity(GO:0008332)
0.0 0.6 GO:0004767 sphingomyelin phosphodiesterase activity(GO:0004767)
0.0 0.9 GO:0031681 G-protein beta-subunit binding(GO:0031681)
0.0 2.0 GO:0008013 beta-catenin binding(GO:0008013)
0.0 0.2 GO:0042978 ornithine decarboxylase activator activity(GO:0042978)
0.0 1.0 GO:0017080 sodium channel regulator activity(GO:0017080)
0.0 3.1 GO:0008138 protein tyrosine/serine/threonine phosphatase activity(GO:0008138)
0.0 1.4 GO:0004435 phosphatidylinositol phospholipase C activity(GO:0004435) phospholipase C activity(GO:0004629)
0.0 0.7 GO:0072542 phosphatase activator activity(GO:0019211) protein phosphatase activator activity(GO:0072542)
0.0 0.5 GO:0016861 intramolecular oxidoreductase activity, interconverting aldoses and ketoses(GO:0016861)
0.0 0.8 GO:0017134 fibroblast growth factor binding(GO:0017134)
0.0 0.8 GO:0019209 kinase activator activity(GO:0019209) protein kinase activator activity(GO:0030295)
0.0 1.2 GO:0031624 ubiquitin conjugating enzyme binding(GO:0031624)
0.0 0.3 GO:0016907 G-protein coupled acetylcholine receptor activity(GO:0016907)
0.0 0.3 GO:0047498 calcium-dependent phospholipase A2 activity(GO:0047498)
0.0 0.4 GO:0004535 poly(A)-specific ribonuclease activity(GO:0004535)
0.0 0.2 GO:0000217 DNA secondary structure binding(GO:0000217)
0.0 0.8 GO:0004707 MAP kinase activity(GO:0004707)
0.0 0.8 GO:0019003 GDP binding(GO:0019003)
0.0 0.4 GO:0000175 3'-5'-exoribonuclease activity(GO:0000175)
0.0 3.5 GO:0000287 magnesium ion binding(GO:0000287)
0.0 1.4 GO:0051287 NAD binding(GO:0051287)
0.0 0.4 GO:0036002 pre-mRNA binding(GO:0036002)
0.0 0.6 GO:0008331 high voltage-gated calcium channel activity(GO:0008331)
0.0 1.8 GO:0003713 transcription coactivator activity(GO:0003713)
0.0 3.8 GO:0046982 protein heterodimerization activity(GO:0046982)
0.0 0.1 GO:0071916 dipeptide transporter activity(GO:0042936) dipeptide transmembrane transporter activity(GO:0071916)
0.0 0.9 GO:0061631 ubiquitin conjugating enzyme activity(GO:0061631)
0.0 5.4 GO:0061630 ubiquitin protein ligase activity(GO:0061630)
0.0 0.9 GO:0003697 single-stranded DNA binding(GO:0003697)
0.0 1.5 GO:0008081 phosphoric diester hydrolase activity(GO:0008081)
0.0 0.1 GO:0036042 long-chain fatty acyl-CoA binding(GO:0036042)
0.0 0.6 GO:0003746 translation elongation factor activity(GO:0003746)
0.0 0.6 GO:0031491 nucleosome binding(GO:0031491)
0.0 0.3 GO:0017056 structural constituent of nuclear pore(GO:0017056)
0.0 0.4 GO:0015459 potassium channel regulator activity(GO:0015459)
0.0 0.2 GO:0004720 protein-lysine 6-oxidase activity(GO:0004720)
0.0 1.4 GO:0004843 thiol-dependent ubiquitin-specific protease activity(GO:0004843) thiol-dependent ubiquitinyl hydrolase activity(GO:0036459) ubiquitinyl hydrolase activity(GO:0101005)
0.0 0.7 GO:0004715 non-membrane spanning protein tyrosine kinase activity(GO:0004715)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 4.2 ST ERK1 ERK2 MAPK PATHWAY ERK1/ERK2 MAPK Pathway
0.1 3.6 PID HEDGEHOG GLI PATHWAY Hedgehog signaling events mediated by Gli proteins
0.1 2.7 PID IL2 PI3K PATHWAY IL2 signaling events mediated by PI3K
0.1 0.9 ST P38 MAPK PATHWAY p38 MAPK Pathway
0.1 2.2 PID AURORA A PATHWAY Aurora A signaling
0.1 1.6 PID ARF 3PATHWAY Arf1 pathway
0.1 1.7 SIG INSULIN RECEPTOR PATHWAY IN CARDIAC MYOCYTES Genes related to the insulin receptor pathway
0.1 2.0 SIG BCR SIGNALING PATHWAY Members of the BCR signaling pathway
0.1 1.6 PID DNA PK PATHWAY DNA-PK pathway in nonhomologous end joining
0.1 1.0 SIG PIP3 SIGNALING IN B LYMPHOCYTES Genes related to PIP3 signaling in B lymphocytes
0.1 1.2 PID P38 MKK3 6PATHWAY p38 MAPK signaling pathway
0.1 2.2 PID AR TF PATHWAY Regulation of Androgen receptor activity
0.1 0.5 PID AVB3 INTEGRIN PATHWAY Integrins in angiogenesis
0.1 2.3 PID HES HEY PATHWAY Notch-mediated HES/HEY network
0.1 0.7 PID EPHB FWD PATHWAY EPHB forward signaling
0.1 2.1 PID BCR 5PATHWAY BCR signaling pathway
0.1 0.7 PID REELIN PATHWAY Reelin signaling pathway
0.1 1.3 PID PRL SIGNALING EVENTS PATHWAY Signaling events mediated by PRL
0.1 1.0 PID ARF6 PATHWAY Arf6 signaling events
0.1 0.7 PID RHOA PATHWAY RhoA signaling pathway
0.0 0.7 PID LPA4 PATHWAY LPA4-mediated signaling events
0.0 1.0 PID MYC PATHWAY C-MYC pathway
0.0 2.0 PID P73PATHWAY p73 transcription factor network
0.0 1.3 PID E2F PATHWAY E2F transcription factor network
0.0 0.9 PID MYC ACTIV PATHWAY Validated targets of C-MYC transcriptional activation
0.0 0.3 PID BARD1 PATHWAY BARD1 signaling events
0.0 0.3 PID HDAC CLASSIII PATHWAY Signaling events mediated by HDAC Class III
0.0 0.4 PID CERAMIDE PATHWAY Ceramide signaling pathway
0.0 0.7 PID AR PATHWAY Coregulation of Androgen receptor activity
0.0 0.6 PID CMYB PATHWAY C-MYB transcription factor network
0.0 0.3 PID AJDISS 2PATHWAY Posttranslational regulation of adherens junction stability and dissassembly

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 1.2 REACTOME SYNTHESIS OF BILE ACIDS AND BILE SALTS VIA 24 HYDROXYCHOLESTEROL Genes involved in Synthesis of bile acids and bile salts via 24-hydroxycholesterol
0.2 1.0 REACTOME PD1 SIGNALING Genes involved in PD-1 signaling
0.2 2.3 REACTOME IONOTROPIC ACTIVITY OF KAINATE RECEPTORS Genes involved in Ionotropic activity of Kainate Receptors
0.1 1.7 REACTOME SYNTHESIS OF PE Genes involved in Synthesis of PE
0.1 1.0 REACTOME ELEVATION OF CYTOSOLIC CA2 LEVELS Genes involved in Elevation of cytosolic Ca2+ levels
0.1 1.8 REACTOME SPRY REGULATION OF FGF SIGNALING Genes involved in Spry regulation of FGF signaling
0.1 1.4 REACTOME DARPP 32 EVENTS Genes involved in DARPP-32 events
0.1 0.6 REACTOME VEGF LIGAND RECEPTOR INTERACTIONS Genes involved in VEGF ligand-receptor interactions
0.1 0.9 REACTOME ACTIVATION OF IRF3 IRF7 MEDIATED BY TBK1 IKK EPSILON Genes involved in Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon
0.1 0.7 REACTOME TRANSPORT OF ORGANIC ANIONS Genes involved in Transport of organic anions
0.1 1.3 REACTOME ASSOCIATION OF LICENSING FACTORS WITH THE PRE REPLICATIVE COMPLEX Genes involved in Association of licensing factors with the pre-replicative complex
0.1 0.7 REACTOME PKA MEDIATED PHOSPHORYLATION OF CREB Genes involved in PKA-mediated phosphorylation of CREB
0.1 2.7 REACTOME GLYCOSPHINGOLIPID METABOLISM Genes involved in Glycosphingolipid metabolism
0.1 0.4 REACTOME P38MAPK EVENTS Genes involved in p38MAPK events
0.1 0.8 REACTOME SYNTHESIS SECRETION AND INACTIVATION OF GLP1 Genes involved in Synthesis, Secretion, and Inactivation of Glucagon-like Peptide-1 (GLP-1)
0.1 2.1 REACTOME ANTIGEN ACTIVATES B CELL RECEPTOR LEADING TO GENERATION OF SECOND MESSENGERS Genes involved in Antigen Activates B Cell Receptor Leading to Generation of Second Messengers
0.1 0.8 REACTOME TRAF6 MEDIATED INDUCTION OF TAK1 COMPLEX Genes involved in TRAF6 mediated induction of TAK1 complex
0.1 0.5 REACTOME RAP1 SIGNALLING Genes involved in Rap1 signalling
0.1 0.4 REACTOME RECRUITMENT OF NUMA TO MITOTIC CENTROSOMES Genes involved in Recruitment of NuMA to mitotic centrosomes
0.1 1.1 REACTOME NUCLEAR EVENTS KINASE AND TRANSCRIPTION FACTOR ACTIVATION Genes involved in Nuclear Events (kinase and transcription factor activation)
0.1 0.6 REACTOME NOTCH HLH TRANSCRIPTION PATHWAY Genes involved in Notch-HLH transcription pathway
0.0 0.9 REACTOME DOWNREGULATION OF SMAD2 3 SMAD4 TRANSCRIPTIONAL ACTIVITY Genes involved in Downregulation of SMAD2/3:SMAD4 transcriptional activity
0.0 1.0 REACTOME DEPOSITION OF NEW CENPA CONTAINING NUCLEOSOMES AT THE CENTROMERE Genes involved in Deposition of New CENPA-containing Nucleosomes at the Centromere
0.0 1.0 REACTOME RNA POL I TRANSCRIPTION INITIATION Genes involved in RNA Polymerase I Transcription Initiation
0.0 0.5 REACTOME METABOLISM OF POLYAMINES Genes involved in Metabolism of polyamines
0.0 0.7 REACTOME SYNTHESIS OF PA Genes involved in Synthesis of PA
0.0 1.2 REACTOME NRAGE SIGNALS DEATH THROUGH JNK Genes involved in NRAGE signals death through JNK
0.0 1.0 REACTOME MEIOTIC RECOMBINATION Genes involved in Meiotic Recombination
0.0 0.3 REACTOME FANCONI ANEMIA PATHWAY Genes involved in Fanconi Anemia pathway
0.0 0.5 REACTOME SYNTHESIS OF PIPS AT THE GOLGI MEMBRANE Genes involved in Synthesis of PIPs at the Golgi membrane
0.0 0.8 REACTOME ACTIVATION OF CHAPERONE GENES BY XBP1S Genes involved in Activation of Chaperone Genes by XBP1(S)
0.0 0.3 REACTOME CIRCADIAN CLOCK Genes involved in Circadian Clock
0.0 1.4 REACTOME DNA REPAIR Genes involved in DNA Repair
0.0 0.2 REACTOME SMAD2 SMAD3 SMAD4 HETEROTRIMER REGULATES TRANSCRIPTION Genes involved in SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription
0.0 0.2 REACTOME PROTEOLYTIC CLEAVAGE OF SNARE COMPLEX PROTEINS Genes involved in Proteolytic cleavage of SNARE complex proteins
0.0 0.3 REACTOME ADHERENS JUNCTIONS INTERACTIONS Genes involved in Adherens junctions interactions
0.0 0.7 REACTOME METABOLISM OF VITAMINS AND COFACTORS Genes involved in Metabolism of vitamins and cofactors
0.0 0.2 REACTOME PROCESSING OF INTRONLESS PRE MRNAS Genes involved in Processing of Intronless Pre-mRNAs
0.0 0.8 REACTOME APC C CDH1 MEDIATED DEGRADATION OF CDC20 AND OTHER APC C CDH1 TARGETED PROTEINS IN LATE MITOSIS EARLY G1 Genes involved in APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1
0.0 1.0 REACTOME MRNA SPLICING Genes involved in mRNA Splicing
0.0 0.8 REACTOME GENERIC TRANSCRIPTION PATHWAY Genes involved in Generic Transcription Pathway