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PRJNA195909:zebrafish embryo and larva development

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Results for mtf1

Z-value: 1.19

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Transcription factors associated with mtf1

Gene Symbol Gene ID Gene Info
mtf1
ENSDARG00000102898 metal-regulatory transcription factor 1

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
mtf1dr11_v1_chr16_+_4133519_4133519-0.901.1e-03Click!

Activity profile of mtf1 motif

Sorted Z-values of mtf1 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr11_-_497854 4.71 ENSDART00000104520
cnbpb
CCHC-type zinc finger, nucleic acid binding protein b
chr11_-_497680 3.77 ENSDART00000154888
cnbpb
CCHC-type zinc finger, nucleic acid binding protein b
chr2_-_7666021 3.27 ENSDART00000180007
CABZ01021592.1

chr7_-_74090168 2.60 ENSDART00000050528
tyrp1a
tyrosinase-related protein 1a
chr17_-_125091 2.53 ENSDART00000158825
actc1b
actin, alpha, cardiac muscle 1b
chr8_+_31435452 2.51 ENSDART00000145282
selenop
selenoprotein P
chr7_+_49715750 2.50 ENSDART00000019446
ascl1b
achaete-scute family bHLH transcription factor 1b
chr2_+_33457310 2.18 ENSDART00000056657
zgc:113531
zgc:113531
chr3_+_23221047 2.10 ENSDART00000009393
col1a1a
collagen, type I, alpha 1a
chr25_-_23526058 2.00 ENSDART00000191331
ENSDART00000062930
phlda2
pleckstrin homology-like domain, family A, member 2
chr23_-_20309505 1.90 ENSDART00000130856
lamb2l
laminin, beta 2-like
chr1_-_35928942 1.89 ENSDART00000033566
smad1
SMAD family member 1
chr1_+_44906517 1.79 ENSDART00000142820
wu:fc21g02
wu:fc21g02
chr22_-_37349967 1.75 ENSDART00000104493
sox2
SRY (sex determining region Y)-box 2
chr16_+_26449615 1.62 ENSDART00000039746
epb41b
erythrocyte membrane protein band 4.1b
chr8_+_1065458 1.59 ENSDART00000081432
sprb
sepiapterin reductase b
chr20_-_54259780 1.58 ENSDART00000172631
fkbp3
FK506 binding protein 3
chr1_-_35929143 1.52 ENSDART00000185002
smad1
SMAD family member 1
chr10_+_21789954 1.50 ENSDART00000157769
ENSDART00000171703
pcdh1gc5
protocadherin 1 gamma c 5
chr1_-_59251874 1.48 ENSDART00000168919
olfm2b
olfactomedin 2b
chr7_+_25323742 1.46 ENSDART00000110347
cyp26b1
cytochrome P450, family 26, subfamily b, polypeptide 1
chr1_-_12278056 1.43 ENSDART00000139336
ENSDART00000137463
cplx2l
complexin 2, like
chr1_-_12278522 1.42 ENSDART00000142122
ENSDART00000003825
cplx2l
complexin 2, like
chr14_+_5117072 1.37 ENSDART00000189628
nanos1
nanos homolog 1
chr20_-_147574 1.32 ENSDART00000104762
ENSDART00000131635
slc16a10
solute carrier family 16 (aromatic amino acid transporter), member 10
chr19_+_10832092 1.23 ENSDART00000191851
tomm40l
translocase of outer mitochondrial membrane 40 homolog, like
chr23_+_23485858 1.11 ENSDART00000114067
agrn
agrin
chr8_+_22355909 1.10 ENSDART00000146457
ENSDART00000142883
zgc:153631
zgc:153631
chr6_+_42918933 1.04 ENSDART00000064896
gnat1
guanine nucleotide binding protein (G protein), alpha transducing activity polypeptide 1
chr11_-_3334248 1.04 ENSDART00000154314
ENSDART00000121861
prph
peripherin
chr23_-_28239750 0.98 ENSDART00000003548
znf385a
zinc finger protein 385A
chr23_+_36178104 0.98 ENSDART00000103131
hoxc1a
homeobox C1a
chr12_-_45876387 0.97 ENSDART00000043210
ENSDART00000149044
pax2b
paired box 2b
chr23_-_45705525 0.93 ENSDART00000148959
ednrab
endothelin receptor type Ab
chr1_+_50085440 0.89 ENSDART00000018469
ENSDART00000134988
npnt
nephronectin
chr4_+_38981587 0.88 ENSDART00000142713
si:dkey-66k12.3
si:dkey-66k12.3
chr17_-_36988455 0.87 ENSDART00000187180
ENSDART00000126823
dnmt3ab
DNA (cytosine-5-)-methyltransferase 3 alpha b
chr24_-_38384432 0.85 ENSDART00000140739
lrrc4bb
leucine rich repeat containing 4Bb
chr14_+_597532 0.84 ENSDART00000159805
LO018568.2

chr24_-_37877743 0.83 ENSDART00000105658
tmem204
transmembrane protein 204
chr19_+_37701450 0.82 ENSDART00000087694
thsd7aa
thrombospondin, type I, domain containing 7Aa
chr1_+_50085640 0.78 ENSDART00000158988
ENSDART00000165973
npnt
nephronectin
chr20_-_46362606 0.78 ENSDART00000153087
bmf2
BCL2 modifying factor 2
chr17_-_12385308 0.74 ENSDART00000080927
snap25b
synaptosomal-associated protein, 25b
chr7_-_38861741 0.72 ENSDART00000173629
ENSDART00000037361
ENSDART00000173953
phf21aa
PHD finger protein 21Aa
chr24_-_4450238 0.68 ENSDART00000066835
fzd8a
frizzled class receptor 8a
chr23_+_20931030 0.67 ENSDART00000167014
pax7b
paired box 7b
chr19_+_31183495 0.67 ENSDART00000088618
meox2b
mesenchyme homeobox 2b
chr8_-_39977026 0.65 ENSDART00000141707
asphd2
aspartate beta-hydroxylase domain containing 2
chr2_+_54641644 0.65 ENSDART00000027313
ndufv2
NADH dehydrogenase (ubiquinone) flavoprotein 2
chr1_+_9004719 0.63 ENSDART00000006211
ENSDART00000137211
prkcba
protein kinase C, beta a
chr4_+_57099307 0.63 ENSDART00000131654
si:ch211-238e22.2
si:ch211-238e22.2
chr24_+_10397865 0.61 ENSDART00000155557
si:ch211-69l10.4
si:ch211-69l10.4
chr6_-_20875111 0.60 ENSDART00000115118
ENSDART00000159916
tns1a
tensin 1a
chr14_-_45394704 0.60 ENSDART00000173078
ENSDART00000125970
si:ch211-168f7.5
si:ch211-168f7.5
chr10_+_22724059 0.59 ENSDART00000136123
kdm6bb
lysine (K)-specific demethylase 6B, b
chr19_-_33212023 0.55 ENSDART00000189209
trib1
tribbles pseudokinase 1
chr24_+_28525507 0.55 ENSDART00000191121
arhgap29a
Rho GTPase activating protein 29a
chr13_+_52006253 0.55 ENSDART00000181259
CABZ01080135.1

chr12_-_45875946 0.54 ENSDART00000149970
pax2b
paired box 2b
chr11_+_575665 0.53 ENSDART00000122133
mkrn2os.1
MKRN2 opposite strand, tandem duplicate 1
chr2_-_51095743 0.53 ENSDART00000184646
THEM6
si:ch73-52e5.2
chr9_+_156142 0.52 ENSDART00000171501
cldn10b
claudin 10b
chr8_+_8973425 0.52 ENSDART00000066107
bcap31
B cell receptor associated protein 31
chr4_-_28334464 0.51 ENSDART00000123617
celsr1a
cadherin EGF LAG seven-pass G-type receptor 1a
chr15_-_30816370 0.51 ENSDART00000142982
ENSDART00000050649
ENSDART00000136901
ENSDART00000100194
msi2b
musashi RNA-binding protein 2b
chr10_-_26997344 0.51 ENSDART00000146595
zgc:193742
zgc:193742
chr8_+_38417461 0.50 ENSDART00000132718
nkx6.3
NK6 homeobox 3
chr4_-_28335184 0.47 ENSDART00000178149
ENSDART00000043737
celsr1a
cadherin EGF LAG seven-pass G-type receptor 1a
chr3_+_30500968 0.47 ENSDART00000103447
si:dkey-13n23.3
si:dkey-13n23.3
chr23_+_45611649 0.45 ENSDART00000169521
dclk2b
doublecortin-like kinase 2b
chr7_+_59169081 0.45 ENSDART00000167980
ostc
oligosaccharyltransferase complex subunit
chr12_+_20149707 0.43 ENSDART00000181942
foxj1b
forkhead box J1b
chr20_-_1314537 0.42 ENSDART00000144288
pcmt
protein-L-isoaspartate (D-aspartate) O-methyltransferase
chr23_-_45682136 0.41 ENSDART00000164646
fam160a1b
family with sequence similarity 160, member A1b
chr23_-_3681026 0.40 ENSDART00000192128
ENSDART00000040086
pacsin1a
protein kinase C and casein kinase substrate in neurons 1a
chr3_+_30501135 0.40 ENSDART00000165869
si:dkey-13n23.3
si:dkey-13n23.3
chr23_+_45611980 0.38 ENSDART00000181582
dclk2b
doublecortin-like kinase 2b
chr16_-_29452039 0.38 ENSDART00000148960
si:ch211-113g11.6
si:ch211-113g11.6
chr4_-_68564988 0.37 ENSDART00000191212
BX548011.3

chr21_+_21621042 0.37 ENSDART00000134907
tgfb1b
transforming growth factor, beta 1b
chr16_+_11029762 0.37 ENSDART00000091183
erfl3
Ets2 repressor factor like 3
chr12_+_22745618 0.36 ENSDART00000181024
ENSDART00000183993
ENSDART00000077548
ablim2
actin binding LIM protein family, member 2
chr3_-_18756076 0.36 ENSDART00000055766
zgc:113333
zgc:113333
chr20_-_1314355 0.33 ENSDART00000152436
pcmt
protein-L-isoaspartate (D-aspartate) O-methyltransferase
chr16_-_7692568 0.32 ENSDART00000148980
pimr209
Pim proto-oncogene, serine/threonine kinase, related 209
chr20_-_5267600 0.32 ENSDART00000099258
cyp46a1.4
cytochrome P450, family 46, subfamily A, polypeptide 1, tandem duplicate 4
chr17_+_25481466 0.31 ENSDART00000139451
aim1a
crystallin beta-gamma domain containing 1a
chr24_-_37877554 0.30 ENSDART00000132219
tmem204
transmembrane protein 204
chr6_+_612330 0.30 ENSDART00000166872
ENSDART00000191758
kynu
kynureninase
chr25_-_36020344 0.27 ENSDART00000181448
rbl2
retinoblastoma-like 2 (p130)
chr15_+_3219134 0.26 ENSDART00000113532
LO017656.1

chr15_-_18429550 0.25 ENSDART00000136208
ncam1b
neural cell adhesion molecule 1b
chr14_-_3070613 0.25 ENSDART00000193729
ENSDART00000090196
slc35a4
solute carrier family 35, member A4
chr12_-_44070043 0.24 ENSDART00000180059
si:ch73-329n5.3
si:ch73-329n5.3
chr17_+_48831579 0.24 ENSDART00000154824
ENSDART00000178697
ENSDART00000192703
ENSDART00000180378
daam2
dishevelled associated activator of morphogenesis 2
chr3_-_50124413 0.23 ENSDART00000189920
cldnk
claudin k
chr17_+_51499789 0.22 ENSDART00000187701
CABZ01067581.1

chr9_-_128036 0.20 ENSDART00000165960
FQ377903.2

chr24_-_3477103 0.19 ENSDART00000143723
idi1
isopentenyl-diphosphate delta isomerase 1
chr3_+_23029934 0.18 ENSDART00000110343
nags
N-acetylglutamate synthase
chr10_+_24445698 0.18 ENSDART00000146370
slc7a1
solute carrier family 7 (cationic amino acid transporter, y+ system), member 1
chr4_+_53268458 0.17 ENSDART00000165335
si:dkey-250k10.1
si:dkey-250k10.1
chr22_-_38607504 0.16 ENSDART00000164609
si:ch211-126j24.1
si:ch211-126j24.1
chr6_+_31684 0.15 ENSDART00000188853
ENSDART00000184553
CZQB01141835.2

chr4_-_49582108 0.15 ENSDART00000154999
si:dkey-159n16.2
si:dkey-159n16.2
chr12_+_41991635 0.15 ENSDART00000186161
ENSDART00000192510
TCERG1L
transcription elongation regulator 1 like
chr5_-_24270989 0.14 ENSDART00000146251
si:ch211-137i24.12
si:ch211-137i24.12
chr22_-_30678518 0.13 ENSDART00000138282
si:dkey-42l16.1
si:dkey-42l16.1
chr7_+_21275152 0.13 ENSDART00000173612
serpinh2
serine (or cysteine) peptidase inhibitor, clade H, member 2
chr12_-_48312647 0.12 ENSDART00000114415
ascc1
activating signal cointegrator 1 complex subunit 1
chr19_-_11336782 0.11 ENSDART00000131014
sept7a
septin 7a
chr2_+_41876595 0.11 ENSDART00000112243
crlf1a
cytokine receptor-like factor 1a
chr12_+_48851381 0.11 ENSDART00000187241
ENSDART00000187796
dlg5b.1
discs, large homolog 5b (Drosophila), tandem duplicate 1
chr1_-_16394814 0.11 ENSDART00000013024
fgf20a
fibroblast growth factor 20a
chr9_-_48397702 0.10 ENSDART00000147169
zgc:172182
zgc:172182
chr4_-_72513569 0.10 ENSDART00000174130
CR788316.4

chr19_-_35400819 0.10 ENSDART00000148080
rnf19b
ring finger protein 19B
chr18_-_50947868 0.09 ENSDART00000174276
st7
suppression of tumorigenicity 7
chr5_-_14211487 0.08 ENSDART00000135731
npffr1l2
neuropeptide FF receptor 1 like 2
chr7_+_74150839 0.08 ENSDART00000160195
ppp1cbl
protein phosphatase 1, catalytic subunit, beta isoform, like
chr10_+_4807913 0.06 ENSDART00000186099
palm2
paralemmin 2
chr2_+_33796207 0.05 ENSDART00000124647
kiss1ra
KISS1 receptor a
chr3_+_53052769 0.05 ENSDART00000156935
pbx4
pre-B-cell leukemia transcription factor 4
chr4_+_58667348 0.04 ENSDART00000186596
ENSDART00000180673
CR388148.2

chr15_-_37719679 0.04 ENSDART00000184025
si:dkey-117a8.1
si:dkey-117a8.1
chr6_+_10450000 0.03 ENSDART00000151288
ENSDART00000187431
ENSDART00000192474
ENSDART00000188214
ENSDART00000184766
ENSDART00000190082
kcnh7
potassium channel, voltage gated eag related subfamily H, member 7
chr15_+_2559875 0.03 ENSDART00000178505
SH2B2
SH2B adaptor protein 2
chr20_+_13894123 0.01 ENSDART00000007744
slc30a1a
solute carrier family 30 (zinc transporter), member 1a
chr6_+_7553085 0.01 ENSDART00000150939
ENSDART00000151114
myh10
myosin, heavy chain 10, non-muscle
chr22_+_569565 0.01 ENSDART00000037069
usp49
ubiquitin specific peptidase 49
chr8_+_26059677 0.00 ENSDART00000009178
impdh2
IMP (inosine 5'-monophosphate) dehydrogenase 2
chr12_-_25294096 0.00 ENSDART00000183398
hcar1-4
hydroxycarboxylic acid receptor 1-4

Network of associatons between targets according to the STRING database.

First level regulatory network of mtf1

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
1.7 8.5 GO:2000767 positive regulation of cytoplasmic translation(GO:2000767)
0.5 2.1 GO:0035630 bone mineralization involved in bone maturation(GO:0035630)
0.5 1.5 GO:0035992 tendon formation(GO:0035992)
0.4 2.5 GO:0001887 selenium compound metabolic process(GO:0001887)
0.4 1.1 GO:1902571 regulation of serine-type peptidase activity(GO:1902571)
0.3 2.6 GO:0042438 melanin biosynthetic process(GO:0042438)
0.3 1.8 GO:0021982 pineal gland development(GO:0021982)
0.2 0.7 GO:0021531 spinal cord radial glial cell differentiation(GO:0021531) eye field cell fate commitment involved in camera-type eye formation(GO:0060898)
0.2 1.6 GO:0046146 tetrahydrobiopterin biosynthetic process(GO:0006729) tetrahydrobiopterin metabolic process(GO:0046146)
0.2 0.9 GO:0003319 cardioblast migration to the midline involved in heart rudiment formation(GO:0003319)
0.1 0.7 GO:0050938 regulation of xanthophore differentiation(GO:0050938)
0.1 0.5 GO:0070973 protein localization to endoplasmic reticulum exit site(GO:0070973)
0.1 0.6 GO:1900108 negative regulation of nodal signaling pathway(GO:1900108)
0.1 1.0 GO:0035588 adenosine receptor signaling pathway(GO:0001973) purinergic receptor signaling pathway(GO:0035587) G-protein coupled purinergic receptor signaling pathway(GO:0035588)
0.1 1.1 GO:2000406 positive regulation of lymphocyte migration(GO:2000403) positive regulation of T cell migration(GO:2000406)
0.1 0.6 GO:0071557 histone H3-K27 demethylation(GO:0071557)
0.1 0.2 GO:0014014 negative regulation of gliogenesis(GO:0014014)
0.1 0.2 GO:0097052 L-kynurenine metabolic process(GO:0097052) L-kynurenine catabolic process(GO:0097053)
0.1 1.4 GO:0008354 germ cell migration(GO:0008354)
0.1 1.2 GO:0030150 protein import into mitochondrial matrix(GO:0030150)
0.1 1.9 GO:0070831 basement membrane assembly(GO:0070831)
0.1 3.8 GO:0060395 SMAD protein signal transduction(GO:0060395)
0.1 2.9 GO:0046928 regulation of neurotransmitter secretion(GO:0046928)
0.1 0.7 GO:0045162 clustering of voltage-gated sodium channels(GO:0045162)
0.0 0.2 GO:0006526 arginine biosynthetic process(GO:0006526)
0.0 2.2 GO:0030514 negative regulation of BMP signaling pathway(GO:0030514)
0.0 2.5 GO:0021575 hindbrain morphogenesis(GO:0021575)
0.0 0.5 GO:0021772 olfactory bulb development(GO:0021772) olfactory lobe development(GO:0021988)
0.0 0.2 GO:0009240 isopentenyl diphosphate biosynthetic process(GO:0009240) isopentenyl diphosphate metabolic process(GO:0046490)
0.0 0.7 GO:0006120 mitochondrial electron transport, NADH to ubiquinone(GO:0006120)
0.0 0.8 GO:0010507 negative regulation of autophagy(GO:0010507)
0.0 0.3 GO:0006707 cholesterol catabolic process(GO:0006707) sterol catabolic process(GO:0016127)
0.0 0.9 GO:0006305 DNA alkylation(GO:0006305) DNA methylation(GO:0006306)
0.0 0.4 GO:0060088 auditory receptor cell stereocilium organization(GO:0060088)
0.0 1.6 GO:0030866 cortical actin cytoskeleton organization(GO:0030866)
0.0 0.8 GO:0072015 glomerular visceral epithelial cell development(GO:0072015) glomerular epithelial cell development(GO:0072310)
0.0 1.0 GO:0045104 intermediate filament-based process(GO:0045103) intermediate filament cytoskeleton organization(GO:0045104)
0.0 0.4 GO:0097320 membrane tubulation(GO:0097320)
0.0 0.3 GO:2000134 negative regulation of cell cycle G1/S phase transition(GO:1902807) negative regulation of G1/S transition of mitotic cell cycle(GO:2000134)
0.0 0.3 GO:0015781 pyrimidine nucleotide-sugar transport(GO:0015781) pyrimidine nucleotide-sugar transmembrane transport(GO:0090481)
0.0 0.4 GO:0030032 lamellipodium assembly(GO:0030032)
0.0 2.0 GO:0043068 positive regulation of cell death(GO:0010942) positive regulation of apoptotic process(GO:0043065) positive regulation of programmed cell death(GO:0043068)
0.0 0.1 GO:0046850 regulation of bone remodeling(GO:0046850)
0.0 0.7 GO:0032436 positive regulation of proteasomal ubiquitin-dependent protein catabolic process(GO:0032436) positive regulation of proteasomal protein catabolic process(GO:1901800)
0.0 1.5 GO:0007422 peripheral nervous system development(GO:0007422)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 2.6 GO:0045009 melanosome membrane(GO:0033162) chitosome(GO:0045009)
0.2 3.4 GO:0071144 SMAD2-SMAD3 protein complex(GO:0071144)
0.2 2.5 GO:0005869 dynactin complex(GO:0005869)
0.1 0.7 GO:0070032 synaptobrevin 2-SNAP-25-syntaxin-1a-complexin I complex(GO:0070032)
0.1 2.9 GO:0043195 terminal bouton(GO:0043195)
0.1 1.2 GO:0005742 mitochondrial outer membrane translocase complex(GO:0005742)
0.1 1.9 GO:0043256 basal lamina(GO:0005605) laminin complex(GO:0043256)
0.0 2.2 GO:0032281 AMPA glutamate receptor complex(GO:0032281)
0.0 1.4 GO:0060293 germ plasm(GO:0060293)
0.0 0.1 GO:0097058 CRLF-CLCF1 complex(GO:0097058)
0.0 0.4 GO:0008250 oligosaccharyltransferase complex(GO:0008250)
0.0 0.6 GO:0044666 MLL3/4 complex(GO:0044666)
0.0 1.2 GO:0030964 mitochondrial respiratory chain complex I(GO:0005747) NADH dehydrogenase complex(GO:0030964) respiratory chain complex I(GO:0045271)
0.0 2.1 GO:0005581 collagen trimer(GO:0005581)
0.0 2.5 GO:0090575 RNA polymerase II transcription factor complex(GO:0090575)
0.0 1.0 GO:0005834 heterotrimeric G-protein complex(GO:0005834)
0.0 0.5 GO:0005844 polysome(GO:0005844)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 2.5 GO:0008430 selenium binding(GO:0008430)
0.5 1.5 GO:0008401 retinoic acid 4-hydroxylase activity(GO:0008401)
0.3 1.3 GO:0015349 thyroid hormone transmembrane transporter activity(GO:0015349)
0.2 9.9 GO:0045182 translation regulator activity(GO:0045182)
0.2 0.6 GO:0031434 mitogen-activated protein kinase kinase binding(GO:0031434)
0.2 3.4 GO:0070411 I-SMAD binding(GO:0070411)
0.1 0.9 GO:0004962 endothelin receptor activity(GO:0004962)
0.1 0.7 GO:0004719 protein-L-isoaspartate (D-aspartate) O-methyltransferase activity(GO:0004719)
0.1 3.6 GO:0017075 syntaxin-1 binding(GO:0017075)
0.1 1.2 GO:0008320 protein transmembrane transporter activity(GO:0008320)
0.1 0.9 GO:0003886 DNA (cytosine-5-)-methyltransferase activity(GO:0003886)
0.1 0.4 GO:0034714 type III transforming growth factor beta receptor binding(GO:0034714)
0.1 0.2 GO:0034618 arginine binding(GO:0034618)
0.1 0.6 GO:0071558 histone demethylase activity (H3-K27 specific)(GO:0071558)
0.1 0.3 GO:0033781 cholesterol 24-hydroxylase activity(GO:0033781)
0.0 1.1 GO:0043236 laminin binding(GO:0043236)
0.0 0.4 GO:0001217 bacterial-type RNA polymerase transcription factor activity, sequence-specific DNA binding(GO:0001130) bacterial-type RNA polymerase transcriptional repressor activity, sequence-specific DNA binding(GO:0001217)
0.0 0.2 GO:0016822 hydrolase activity, acting on acid carbon-carbon bonds(GO:0016822) hydrolase activity, acting on acid carbon-carbon bonds, in ketonic substances(GO:0016823)
0.0 0.4 GO:0004563 beta-N-acetylhexosaminidase activity(GO:0004563)
0.0 1.0 GO:0031683 G-protein beta/gamma-subunit complex binding(GO:0031683)
0.0 4.0 GO:0005201 extracellular matrix structural constituent(GO:0005201)
0.0 0.2 GO:0016863 intramolecular oxidoreductase activity, transposing C=C bonds(GO:0016863)
0.0 1.2 GO:0003755 peptidyl-prolyl cis-trans isomerase activity(GO:0003755)
0.0 0.6 GO:0004697 protein kinase C activity(GO:0004697) calcium-dependent protein kinase C activity(GO:0004698)
0.0 0.3 GO:0001102 RNA polymerase II activating transcription factor binding(GO:0001102)
0.0 0.7 GO:0051537 2 iron, 2 sulfur cluster binding(GO:0051537)
0.0 2.0 GO:1901981 phosphatidylinositol phosphate binding(GO:1901981)
0.0 0.3 GO:0015165 pyrimidine nucleotide-sugar transmembrane transporter activity(GO:0015165)
0.0 1.6 GO:0016616 oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor(GO:0016616)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 3.4 PID ALK2 PATHWAY ALK2 signaling events
0.1 2.8 NABA BASEMENT MEMBRANES Genes encoding structural components of basement membranes
0.0 1.0 PID RHODOPSIN PATHWAY Visual signal transduction: Rods
0.0 1.6 PID HDAC CLASSI PATHWAY Signaling events mediated by HDAC Class I
0.0 0.3 SA PTEN PATHWAY PTEN is a tumor suppressor that dephosphorylates the lipid messenger phosphatidylinositol triphosphate.

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 3.4 REACTOME SIGNALING BY BMP Genes involved in Signaling by BMP
0.1 1.1 REACTOME HS GAG BIOSYNTHESIS Genes involved in HS-GAG biosynthesis
0.1 1.5 REACTOME AMINO ACID TRANSPORT ACROSS THE PLASMA MEMBRANE Genes involved in Amino acid transport across the plasma membrane
0.1 1.4 REACTOME CYTOCHROME P450 ARRANGED BY SUBSTRATE TYPE Genes involved in Cytochrome P450 - arranged by substrate type
0.0 1.0 REACTOME G PROTEIN ACTIVATION Genes involved in G-protein activation
0.0 0.5 REACTOME APOPTOTIC CLEAVAGE OF CELLULAR PROTEINS Genes involved in Apoptotic cleavage of cellular proteins
0.0 0.2 REACTOME TRYPTOPHAN CATABOLISM Genes involved in Tryptophan catabolism
0.0 0.7 REACTOME RESPIRATORY ELECTRON TRANSPORT Genes involved in Respiratory electron transport