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PRJNA195909:zebrafish embryo and larva development

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Results for msx2b

Z-value: 0.45

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Transcription factors associated with msx2b

Gene Symbol Gene ID Gene Info
ENSDARG00000101023 muscle segment homeobox 2b

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
msx2bdr11_v1_chr21_-_41147818_41147818-0.872.0e-03Click!

Activity profile of msx2b motif

Sorted Z-values of msx2b motif

Promoter Log-likelihood Transcript Gene Gene Info
chr2_-_50225411 1.14 ENSDART00000147117
ENSDART00000000042
MCM6 minichromosome maintenance deficient 6, like
chr10_-_25217347 0.91 ENSDART00000036906
karyopherin alpha 7 (importin alpha 8)
chr12_-_42368296 0.75 ENSDART00000171075
zgc:111868
chr9_+_29548195 0.57 ENSDART00000176057
ring finger protein 17
chr8_-_1838315 0.54 ENSDART00000114476
ENSDART00000140077
phosphatidylinositol 4-kinase, catalytic, alpha b
chr9_+_20780813 0.52 ENSDART00000142787
family with sequence similarity 46, member C
chr25_+_5604512 0.50 ENSDART00000042781
plexin b2b
chr11_+_25539698 0.49 ENSDART00000035602
CXXC finger protein 1b
chr5_-_9216758 0.48 ENSDART00000134896
ENSDART00000147000
low-density lipoprotein receptor related-protein 13
chr20_-_23426339 0.48 ENSDART00000004625
zygote arrest 1
chr10_+_10972795 0.48 ENSDART00000127331
cell division cycle 37-like 1
chr17_-_50054025 0.48 ENSDART00000190105

chr22_-_16755885 0.42 ENSDART00000036467
PATJ, crumbs cell polarity complex component
chr5_-_15264007 0.41 ENSDART00000180641
guanine nucleotide binding protein (G protein), beta polypeptide 1-like
chr5_-_61609448 0.36 ENSDART00000133426
si:dkey-261j4.5
chr11_+_6881001 0.35 ENSDART00000170331
kelch-like family member 26
chr23_-_27692717 0.34 ENSDART00000053878
ENSDART00000145028
si:dkey-166n8.9
chr11_+_2687395 0.32 ENSDART00000082510
UDP-Gal:betaGal beta 1,3-galactosyltransferase polypeptide 6
chr15_-_34408777 0.31 ENSDART00000139934
alkylglycerol monooxygenase
chr14_-_899170 0.31 ENSDART00000165211
ENSDART00000031992
regulator of G protein signaling 14a
chr18_-_26715655 0.30 ENSDART00000181497
MALT paracaspase 3
chr2_-_26590628 0.29 ENSDART00000025120
NDC1 transmembrane nucleoporin
chr1_+_34203817 0.27 ENSDART00000191432
ENSDART00000046094
ADP-ribosylation factor-like 6
chr6_-_54433995 0.27 ENSDART00000017230
small nuclear ribonucleoprotein polypeptide C
chr1_+_54137089 0.26 ENSDART00000062945

chr10_+_20392083 0.25 ENSDART00000166867
R3H domain and coiled-coil containing 1
chr21_-_31013817 0.25 ENSDART00000065504
nuclear cap binding subunit 3
chr17_-_6955082 0.25 ENSDART00000109228
zinc finger and BTB domain containing 24
chr3_-_31619463 0.25 ENSDART00000124559
minamoto
chr11_+_44804685 0.25 ENSDART00000163660
striatin, calmodulin binding protein
chr10_+_6013076 0.25 ENSDART00000167613
ENSDART00000159216
3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble)
chr10_-_18463934 0.23 ENSDART00000133116
ENSDART00000113422
si:dkey-28o19.1
chr23_-_31913069 0.23 ENSDART00000135526
mitochondrial fission regulator 2
chr6_+_59984772 0.23 ENSDART00000048449
mitochondrial translational release factor 1
chr17_+_21477892 0.22 ENSDART00000155309
phospholipase A2, group IVF, tandem duplicate 2
chr22_-_547748 0.22 ENSDART00000037455
ENSDART00000140101
cyclin D3
chr10_+_5954787 0.22 ENSDART00000161887
ENSDART00000160345
ENSDART00000190046
mitogen-activated protein kinase kinase kinase 1, E3 ubiquitin protein ligase
chr8_-_26792912 0.22 ENSDART00000139787
kazrin, periplakin interacting protein a
chr11_+_17984354 0.22 ENSDART00000179986
RNA pseudouridylate synthase domain containing 4
chr7_-_64971839 0.21 ENSDART00000164682
SIN3-HDAC complex associated factor, like
chr18_-_17147803 0.21 ENSDART00000187986
ENSDART00000169080
zinc finger CCCH-type containing 18
chr21_+_10712823 0.21 ENSDART00000123476
lectin, mannose-binding, 1
chr19_+_24891747 0.21 ENSDART00000132209
ENSDART00000193610
EYA transcriptional coactivator and phosphatase 3
chr2_+_42871831 0.21 ENSDART00000171393
EFR3 homolog A (S. cerevisiae)
chr25_+_25085349 0.20 ENSDART00000192166
si:ch73-182e20.4
chr13_-_4018888 0.20 ENSDART00000058238
tight junction associated protein 1 (peripheral)
chr21_+_21195487 0.20 ENSDART00000181746
ENSDART00000184832
RPTOR independent companion of MTOR, complex 2b
chr12_+_10115964 0.20 ENSDART00000152369
si:dkeyp-118b1.2
chr19_-_7441948 0.20 ENSDART00000003544
GA binding protein transcription factor, beta subunit 2a
chr3_+_22035863 0.19 ENSDART00000177169
cell division cycle 27
chr11_+_42765963 0.19 ENSDART00000156080
ENSDART00000179888
tudor domain containing 3
chr18_-_17147600 0.19 ENSDART00000141873
zinc finger CCCH-type containing 18
chr14_-_41272034 0.18 ENSDART00000191709
ENSDART00000074438
centromere protein I
chr18_-_16907436 0.18 ENSDART00000146464
switching B cell complex subunit SWAP70b
chr17_-_18898115 0.18 ENSDART00000028044
galactosylceramidase b
chr19_+_6990970 0.18 ENSDART00000158758
ENSDART00000160482
ENSDART00000193566
kinesin family member C1
chr10_-_41157135 0.17 ENSDART00000134851
AP2 associated kinase 1b
chr19_+_21362553 0.17 ENSDART00000122002
teashirt zinc finger homeobox 1
chr11_+_17984167 0.17 ENSDART00000020283
ENSDART00000188329
RNA pseudouridylate synthase domain containing 4
chr7_-_26532089 0.17 ENSDART00000121698
SUMO1/sentrin/SMT3 specific peptidase 3b
chr1_-_45213565 0.17 ENSDART00000145757
DEAD (Asp-Glu-Ala-Asp) box polypeptide 39Aa
chr3_-_13509283 0.17 ENSDART00000166832
solute carrier family 25 (mitochondrial thiamine pyrophosphate carrier), member 19
chr3_-_13461361 0.17 ENSDART00000080807
F-box and WD repeat domain containing 9
chr10_+_44692272 0.16 ENSDART00000157458
ubiquitin C
chr19_+_20540843 0.16 ENSDART00000192500
potassium voltage-gated channel, subfamily H (eag-related), member 8
chr6_+_6828167 0.16 ENSDART00000181284
si:ch211-85n16.4
chr18_-_45761868 0.16 ENSDART00000025423
cleavage stimulation factor, 3' pre-RNA, subunit 3
chr5_-_29512538 0.16 ENSDART00000098364
euchromatic histone-lysine N-methyltransferase 1a
chr11_-_6880725 0.16 ENSDART00000007204
DEAD (Asp-Glu-Ala-Asp) box polypeptide 49
chr9_-_27720612 0.16 ENSDART00000000566
general transcription factor IIE, polypeptide 1, alpha
chr20_-_51186524 0.16 ENSDART00000027836
ENSDART00000114407
RNA binding motif protein 25b
chr3_+_22935183 0.16 ENSDART00000157378
histone deacetylase 5
chr23_-_31913231 0.15 ENSDART00000146852
ENSDART00000085054
mitochondrial fission regulator 2
chr14_+_23874062 0.15 ENSDART00000172149
SH3 domain containing ring finger 2
chr17_-_21162821 0.15 ENSDART00000157283
abhydrolase domain containing 12
chr16_-_21917361 0.15 ENSDART00000171818
SET domain, bifurcated 1b
chr5_-_4297459 0.15 ENSDART00000018895
serrate RNA effector molecule homolog (Arabidopsis)
chr11_-_45152702 0.14 ENSDART00000168066
arylformamidase
chr6_-_15641686 0.14 ENSDART00000135583
melanophilin a
chr11_-_28911172 0.14 ENSDART00000168493
immunoglobin superfamily, member 21a
chr17_+_1496107 0.14 ENSDART00000187804

chr15_+_2190229 0.14 ENSDART00000147710
arginine/serine-rich coiled-coil 1
chr21_+_4313039 0.14 ENSDART00000141146
si:dkey-84o3.4
chr22_-_14739491 0.14 ENSDART00000133385
low density lipoprotein receptor-related protein 1Ba
chr7_+_15313443 0.14 ENSDART00000045385
mesoderm posterior ba
chr12_-_3992839 0.13 ENSDART00000126100
si:ch211-136m16.8
chr24_+_26017094 0.13 ENSDART00000137851
transferrin receptor 1b
chr20_-_20355577 0.13 ENSDART00000018500
hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) b
chr23_-_25135046 0.13 ENSDART00000184844
ENSDART00000103989
isocitrate dehydrogenase 3 (NAD+) gamma
chr10_+_16165533 0.12 ENSDART00000065045
proline-rich coiled-coil 1
chr19_-_12392819 0.12 ENSDART00000052239
protein tyrosine phosphatase, non-receptor type 2, b
chr20_+_14810886 0.12 ENSDART00000010550
phosphatidylinositol glycan anchor biosynthesis, class C
chr1_+_45002971 0.12 ENSDART00000021336
DnaJ (Hsp40) homolog, subfamily A, member 1
chr22_-_20514043 0.12 ENSDART00000088890
ATPase phospholipid transporting 8B3
chr20_-_2134620 0.11 ENSDART00000064375
transmembrane protein 244
chr3_-_44059902 0.11 ENSDART00000158485
ENSDART00000159088
ENSDART00000165628
interleukin 4 receptor, tandem duplicate 1
chr6_-_52348562 0.11 ENSDART00000142565
ENSDART00000145369
ENSDART00000016890
eukaryotic translation initiation factor 6
chr4_+_17671164 0.11 ENSDART00000040445
N-acetylglucosamine-1-phosphate transferase, alpha and beta subunits
chr15_-_28082310 0.11 ENSDART00000152620
dehydrogenase/reductase (SDR family) member 13a, duplicate 3
chr1_-_24462544 0.11 ENSDART00000184421
ENSDART00000184987
ENSDART00000126950
SH3 domain containing 19
chr8_+_20140321 0.11 ENSDART00000012120
acyl-CoA synthetase bubblegum family member 2
chr1_+_29183962 0.11 ENSDART00000113735
cysteinyl-tRNA synthetase 2, mitochondrial
chr23_-_35064785 0.10 ENSDART00000172240

chr7_-_61901695 0.10 ENSDART00000110328
SH3 domain and tetratricopeptide repeats 1
chr23_+_13375359 0.10 ENSDART00000151947
si:dkey-256k13.2
chr22_+_30543437 0.10 ENSDART00000137983
si:dkey-103k4.1
chr1_+_35194454 0.10 ENSDART00000165389
sc:d189
chr17_-_8656155 0.10 ENSDART00000148990
C-terminal binding protein 2a
chr10_+_9697097 0.10 ENSDART00000167821
RAB GTPase activating protein 1
chr8_+_3426522 0.10 ENSDART00000159466

chr1_+_43686251 0.10 ENSDART00000074604
ENSDART00000137791
CDGSH iron sulfur domain 2
chr19_+_12406583 0.10 ENSDART00000013865
ENSDART00000151535
SEH1-like (S. cerevisiae)
chr19_-_1947403 0.09 ENSDART00000113951
ENSDART00000151293
ENSDART00000134074
zinc and ring finger 2a
chr9_-_2572790 0.09 ENSDART00000135076
ENSDART00000016710
secernin 3
chr13_-_50247689 0.09 ENSDART00000034541
G patch domain containing 11
chr8_-_11324143 0.09 ENSDART00000008215
phosphatidylinositol-4-phosphate 5-kinase, type I, beta b
chr25_-_24248000 0.09 ENSDART00000073527
SPT2 chromatin protein domain containing 1
chr5_+_66433287 0.09 ENSDART00000170757
kinetochore associated 1
chr6_-_29515709 0.08 ENSDART00000180205
peroxisomal biogenesis factor 5-like a
chr14_+_21820034 0.08 ENSDART00000122739
C-terminal binding protein 1
chr22_+_31295791 0.08 ENSDART00000092447
glutamate receptor interacting protein 2b
chr6_+_4229360 0.08 ENSDART00000191347
ENSDART00000130642

chr5_-_61970674 0.08 ENSDART00000143161
zinc finger protein 541
chr20_+_36628059 0.08 ENSDART00000062898
epoxide hydrolase 1, microsomal (xenobiotic)
chr13_+_48359573 0.08 ENSDART00000161959
ENSDART00000165311
mutS homolog 6 (E. coli)
chr3_+_13848226 0.08 ENSDART00000184342
interleukin enhancer binding factor 3b
chr23_-_41965557 0.08 ENSDART00000144183
solute carrier family 1 (glutamate transporter), member 7b
chr23_-_14990865 0.07 ENSDART00000147799
ndrg family member 3b
chr19_-_26923957 0.07 ENSDART00000182390
SKI2 homolog, superkiller viralicidic activity 2-like
chr5_+_67268110 0.06 ENSDART00000148116
si:ch211-110p13.9
chr5_-_38777852 0.06 ENSDART00000131603
si:dkey-58f10.4
chr11_+_29770966 0.06 ENSDART00000088624
ENSDART00000124471
retinitis pigmentosa GTPase regulator b
chr1_+_12068800 0.06 ENSDART00000055566
xeroderma pigmentosum, complementation group A
chr21_+_27513859 0.06 ENSDART00000065420
phosphofurin acidic cluster sorting protein 1a
chr22_+_19264181 0.06 ENSDART00000192750
ENSDART00000137591
ENSDART00000136197
si:dkey-78l4.5
si:dkey-21e2.11
chr10_+_40660772 0.06 ENSDART00000148007
trace amine associated receptor 19l
chr25_-_27729046 0.06 ENSDART00000131437
zgc:153935
chr16_+_13818743 0.06 ENSDART00000090191
folliculin
chr17_+_45607580 0.05 ENSDART00000122583
si:ch211-202f3.4
chr6_-_55347616 0.05 ENSDART00000172081
PDX1 C-terminal inhibiting factor 1
chr10_-_2522588 0.05 ENSDART00000081926

chr5_-_2689753 0.05 ENSDART00000172699
guanine nucleotide binding protein (G protein), gamma 10
chr13_+_2625150 0.05 ENSDART00000164177
phospholipid phosphatase 4
chr15_+_17074185 0.05 ENSDART00000046648
cleft lip and palate associated transmembrane protein 1
chr18_+_10884996 0.05 ENSDART00000147613
microtubule associated monooxygenase, calponin and LIM domain containing 3a
chr2_+_53357953 0.05 ENSDART00000187577
cugbp, Elav-like family member 5b
chr1_+_42225060 0.05 ENSDART00000138740
ENSDART00000101306
catenin (cadherin-associated protein), alpha 2
chr2_+_37176814 0.05 ENSDART00000048277
ENSDART00000176827
coatomer protein complex, subunit alpha
chr5_-_62317496 0.04 ENSDART00000180089
zgc:85789
chr13_+_8958438 0.04 ENSDART00000165721
ENSDART00000169398
3-hydroxyanthranilate 3,4-dioxygenase
chr25_-_16643880 0.04 ENSDART00000104110
ENSDART00000174460
solute carrier family 25 (glutamate carrier), member 18
chr10_-_11353101 0.04 ENSDART00000092110
lin-54 DREAM MuvB core complex component
chr1_-_493218 0.04 ENSDART00000031635
excision repair cross-complementation group 5
chr7_+_69356661 0.04 ENSDART00000177049

chr4_-_6373735 0.04 ENSDART00000140100
si:ch73-156e19.1
chr15_-_23784600 0.04 ENSDART00000059354
RAD1 homolog (S. pombe)
chr3_-_39305291 0.04 ENSDART00000102674
phospholipase C, delta 3a
chr4_+_28997595 0.04 ENSDART00000133357
si:dkey-13e3.1
chr21_+_43402794 0.04 ENSDART00000185572
FERM domain containing 7
chr21_+_15601100 0.03 ENSDART00000180558
ENSDART00000145454
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily b, member 1b
chr15_-_19051152 0.03 ENSDART00000186453
Rho GTPase activating protein 32a
chr5_+_24882633 0.03 ENSDART00000111302
rhomboid domain containing 3
chr17_+_5915875 0.03 ENSDART00000184179
fibronectin type III domain containing 4b
chr22_+_28818291 0.03 ENSDART00000136032
tumor protein p53 binding protein, 2b
chr12_+_46404307 0.03 ENSDART00000185011

chr22_-_18164835 0.03 ENSDART00000143189
regulatory factor X-associated ankyrin-containing protein
chr8_+_17069577 0.03 ENSDART00000131847
si:dkey-190g11.3
chr7_+_24023653 0.03 ENSDART00000141165
TERF1 (TRF1)-interacting nuclear factor 2
chr17_-_200316 0.03 ENSDART00000190561

chr7_-_40145097 0.03 ENSDART00000173634
WD repeat domain 60
chr18_+_33264609 0.03 ENSDART00000050639
vomeronasal 2 receptor, a20
chr8_+_37527575 0.02 ENSDART00000147239
odorant receptor, family H, subfamily 135, member 1
chr18_-_33979422 0.02 ENSDART00000136535
ENSDART00000167698
si:ch211-203b20.7
chr20_+_34870517 0.02 ENSDART00000191797
ankyrin repeat and EF-hand domain containing 1a
chr3_-_43821191 0.02 ENSDART00000186816
stannin
chr25_+_10909850 0.02 ENSDART00000186021

chr24_-_31843173 0.02 ENSDART00000185782
STEAP family member 2, metalloreductase
chr2_-_23778180 0.02 ENSDART00000136782
si:dkey-24c2.7
chr7_+_29512673 0.02 ENSDART00000173895
si:dkey-182o15.5
chr20_+_35484070 0.01 ENSDART00000026234
ENSDART00000141675
meprin A, alpha (PABA peptide hydrolase), tandem duplicate 2
chr8_+_40477264 0.01 ENSDART00000085559
glucokinase (hexokinase 4)
chr12_+_38929663 0.01 ENSDART00000156334
si:dkey-239b22.1
chr21_-_2299002 0.01 ENSDART00000168712
si:ch73-299h12.6
chr7_-_6470431 0.01 ENSDART00000081359
zgc:110425
chr3_-_34296361 0.01 ENSDART00000181485
ENSDART00000113726
trinucleotide repeat containing 6C1
chr19_+_22727940 0.01 ENSDART00000052509
thyrotropin-releasing hormone receptor b
chr6_-_45869127 0.01 ENSDART00000062459
ENSDART00000180563
RNA binding motif protein 19
chr5_+_65493699 0.01 ENSDART00000161567
si:dkey-21e5.1
chr21_+_11560153 0.01 ENSDART00000065842
CD8a molecule
chr13_+_23132666 0.00 ENSDART00000164639
sorbin and SH3 domain containing 1
chr6_-_30210378 0.00 ENSDART00000157359
ENSDART00000113924
leucine rich repeat containing 7
chr16_-_40508624 0.00 ENSDART00000075718
NADH dehydrogenase (ubiquinone) complex I, assembly factor 6
chr11_-_44484952 0.00 ENSDART00000166674
ENSDART00000188016
mitofusin 1b

Network of associatons between targets according to the STRING database.

First level regulatory network of msx2b

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.1 GO:0036388 pre-replicative complex assembly involved in nuclear cell cycle DNA replication(GO:0006267) pre-replicative complex assembly(GO:0036388) pre-replicative complex assembly involved in cell cycle DNA replication(GO:1902299)
0.1 0.5 GO:0032776 DNA methylation on cytosine(GO:0032776)
0.1 0.2 GO:0010142 farnesyl diphosphate biosynthetic process, mevalonate pathway(GO:0010142) isoprenoid biosynthetic process via mevalonate(GO:1902767)
0.1 0.2 GO:0070126 mitochondrial translational termination(GO:0070126)
0.1 0.9 GO:0006607 NLS-bearing protein import into nucleus(GO:0006607)
0.1 0.4 GO:0000455 enzyme-directed rRNA pseudouridine synthesis(GO:0000455)
0.1 0.3 GO:0046485 ether lipid metabolic process(GO:0046485)
0.1 0.2 GO:0015695 organic cation transport(GO:0015695)
0.1 0.2 GO:0001113 DNA-templated transcriptional open complex formation(GO:0001112) transcriptional open complex formation at RNA polymerase II promoter(GO:0001113) protein-DNA complex remodeling(GO:0001120)
0.0 0.2 GO:0006370 7-methylguanosine mRNA capping(GO:0006370)
0.0 0.3 GO:0000395 mRNA 5'-splice site recognition(GO:0000395)
0.0 0.4 GO:0006999 nuclear pore organization(GO:0006999)
0.0 0.1 GO:1902626 mature ribosome assembly(GO:0042256) assembly of large subunit precursor of preribosome(GO:1902626)
0.0 0.1 GO:0051876 pigment granule dispersal(GO:0051876)
0.0 0.2 GO:0007141 male meiosis I(GO:0007141)
0.0 0.1 GO:0015682 ferric iron transport(GO:0015682) transferrin transport(GO:0033572) trivalent inorganic cation transport(GO:0072512)
0.0 0.1 GO:0046462 phosphatidylserine catabolic process(GO:0006660) monoacylglycerol metabolic process(GO:0046462) monoacylglycerol catabolic process(GO:0052651)
0.0 0.2 GO:0048714 positive regulation of glial cell differentiation(GO:0045687) positive regulation of oligodendrocyte differentiation(GO:0048714)
0.0 0.1 GO:0031053 primary miRNA processing(GO:0031053)
0.0 0.1 GO:0010847 regulation of chromatin assembly(GO:0010847)
0.0 0.1 GO:0002532 production of molecular mediator involved in inflammatory response(GO:0002532)
0.0 0.1 GO:0021825 pallium development(GO:0021543) cerebral cortex cell migration(GO:0021795) cerebral cortex tangential migration(GO:0021800) cerebral cortex tangential migration using cell-axon interactions(GO:0021824) substrate-dependent cerebral cortex tangential migration(GO:0021825) gonadotrophin-releasing hormone neuronal migration to the hypothalamus(GO:0021828) hypothalamic tangential migration using cell-axon interactions(GO:0021856) cerebral cortex development(GO:0021987)
0.0 0.1 GO:0016446 somatic diversification of immune receptors via somatic mutation(GO:0002566) pyrimidine dimer repair(GO:0006290) somatic hypermutation of immunoglobulin genes(GO:0016446)
0.0 0.1 GO:0090308 methylation-dependent chromatin silencing(GO:0006346) positive regulation of chromatin silencing(GO:0031937) regulation of methylation-dependent chromatin silencing(GO:0090308) positive regulation of methylation-dependent chromatin silencing(GO:0090309)
0.0 0.1 GO:0010259 multicellular organism aging(GO:0010259)
0.0 0.5 GO:1902285 semaphorin-plexin signaling pathway involved in neuron projection guidance(GO:1902285) semaphorin-plexin signaling pathway involved in axon guidance(GO:1902287)
0.0 0.1 GO:0097101 blood vessel endothelial cell fate specification(GO:0097101)
0.0 0.2 GO:2001239 histone dephosphorylation(GO:0016576) negative regulation of signal transduction in absence of ligand(GO:1901099) regulation of extrinsic apoptotic signaling pathway in absence of ligand(GO:2001239) negative regulation of extrinsic apoptotic signaling pathway in absence of ligand(GO:2001240)
0.0 0.2 GO:0046477 glycosylceramide catabolic process(GO:0046477)
0.0 0.2 GO:0034354 'de novo' NAD biosynthetic process from tryptophan(GO:0034354) 'de novo' NAD biosynthetic process(GO:0034627)
0.0 0.1 GO:1901255 UV-damage excision repair(GO:0070914) nucleotide-excision repair involved in interstrand cross-link repair(GO:1901255)
0.0 0.2 GO:0038203 TORC2 signaling(GO:0038203)
0.0 0.2 GO:0045842 positive regulation of mitotic metaphase/anaphase transition(GO:0045842) positive regulation of mitotic sister chromatid separation(GO:1901970) positive regulation of metaphase/anaphase transition of cell cycle(GO:1902101)
0.0 0.1 GO:0006102 isocitrate metabolic process(GO:0006102)
0.0 0.3 GO:0008354 germ cell migration(GO:0008354)
0.0 0.2 GO:1900087 positive regulation of G1/S transition of mitotic cell cycle(GO:1900087)
0.0 0.1 GO:0070073 clustering of voltage-gated calcium channels(GO:0070073)
0.0 0.0 GO:0006295 nucleotide-excision repair, DNA incision, 3'-to lesion(GO:0006295)
0.0 0.5 GO:0050821 protein stabilization(GO:0050821)
0.0 0.2 GO:0046475 glycerophospholipid catabolic process(GO:0046475)
0.0 0.0 GO:0051823 regulation of synapse structural plasticity(GO:0051823)
0.0 0.1 GO:0006622 protein targeting to lysosome(GO:0006622) carbohydrate phosphorylation(GO:0046835)
0.0 0.2 GO:0016926 protein desumoylation(GO:0016926)
0.0 0.4 GO:0000266 mitochondrial fission(GO:0000266)
0.0 0.2 GO:2000369 regulation of clathrin-mediated endocytosis(GO:2000369)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.1 GO:0042555 MCM complex(GO:0042555)
0.0 0.4 GO:0035145 exon-exon junction complex(GO:0035145)
0.0 0.2 GO:0005673 transcription factor TFIIE complex(GO:0005673)
0.0 0.5 GO:0048188 Set1C/COMPASS complex(GO:0048188)
0.0 0.1 GO:0032301 MutSalpha complex(GO:0032301)
0.0 0.5 GO:0002116 semaphorin receptor complex(GO:0002116)
0.0 0.1 GO:0000506 glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex(GO:0000506)
0.0 0.3 GO:0000243 commitment complex(GO:0000243)
0.0 0.1 GO:0000110 nucleotide-excision repair factor 1 complex(GO:0000110)
0.0 0.1 GO:0055087 Ski complex(GO:0055087)
0.0 0.3 GO:0060170 ciliary membrane(GO:0060170)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 1.1 GO:0043140 ATP-dependent 3'-5' DNA helicase activity(GO:0043140) single-stranded DNA-dependent ATP-dependent 3'-5' DNA helicase activity(GO:1990518)
0.1 0.2 GO:0004421 hydroxymethylglutaryl-CoA synthase activity(GO:0004421)
0.1 0.5 GO:0004430 1-phosphatidylinositol 4-kinase activity(GO:0004430)
0.1 0.9 GO:0061608 nuclear import signal receptor activity(GO:0061608)
0.0 0.1 GO:0004061 arylformamidase activity(GO:0004061)
0.0 0.2 GO:0070016 armadillo repeat domain binding(GO:0070016)
0.0 0.3 GO:0016714 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced pteridine as one donor, and incorporation of one atom of oxygen(GO:0016714)
0.0 0.3 GO:0030619 U1 snRNA binding(GO:0030619)
0.0 0.1 GO:0004998 transferrin receptor activity(GO:0004998)
0.0 0.1 GO:0033961 cis-stilbene-oxide hydrolase activity(GO:0033961)
0.0 0.1 GO:0032357 guanine/thymine mispair binding(GO:0032137) single base insertion or deletion binding(GO:0032138) single thymine insertion binding(GO:0032143) oxidized DNA binding(GO:0032356) oxidized purine DNA binding(GO:0032357) mismatch repair complex binding(GO:0032404) MutLalpha complex binding(GO:0032405)
0.0 0.1 GO:0004449 isocitrate dehydrogenase (NAD+) activity(GO:0004449)
0.0 0.3 GO:0001965 G-protein alpha-subunit binding(GO:0001965)
0.0 0.3 GO:0035250 UDP-galactosyltransferase activity(GO:0035250)
0.0 0.2 GO:0008079 translation release factor activity(GO:0003747) translation termination factor activity(GO:0008079)
0.0 0.2 GO:0045118 azole transporter activity(GO:0045118) azole transmembrane transporter activity(GO:1901474)
0.0 0.4 GO:0009982 pseudouridine synthase activity(GO:0009982)
0.0 0.2 GO:0047498 calcium-dependent phospholipase A2 activity(GO:0047498)
0.0 0.1 GO:0017176 phosphatidylinositol N-acetylglucosaminyltransferase activity(GO:0017176)
0.0 0.1 GO:0043023 ribosomal large subunit binding(GO:0043023)
0.0 0.1 GO:0070004 cysteine-type exopeptidase activity(GO:0070004)
0.0 0.1 GO:0001042 RNA polymerase I core binding(GO:0001042)
0.0 0.1 GO:0046974 histone methyltransferase activity (H3-K9 specific)(GO:0046974)
0.0 0.5 GO:0017154 semaphorin receptor activity(GO:0017154)
0.0 0.2 GO:0005537 mannose binding(GO:0005537)
0.0 0.2 GO:0000340 RNA 7-methylguanosine cap binding(GO:0000340)
0.0 0.2 GO:0035612 AP-2 adaptor complex binding(GO:0035612)
0.0 0.1 GO:0016422 mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity(GO:0016422)
0.0 0.5 GO:0051087 chaperone binding(GO:0051087)
0.0 0.1 GO:0047372 acylglycerol lipase activity(GO:0047372)
0.0 0.2 GO:0032041 histone deacetylase activity (H3-K14 specific)(GO:0031078) NAD-dependent histone deacetylase activity (H3-K14 specific)(GO:0032041)
0.0 0.2 GO:0002039 p53 binding(GO:0002039)
0.0 0.2 GO:0016929 SUMO-specific protease activity(GO:0016929)
0.0 0.1 GO:0052650 NADP-retinol dehydrogenase activity(GO:0052650)
0.0 0.1 GO:0005052 peroxisome matrix targeting signal-1 binding(GO:0005052)
0.0 0.2 GO:0031386 protein tag(GO:0031386)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.2 PID TCR JNK PATHWAY JNK signaling in the CD4+ TCR pathway
0.0 0.2 PID ER NONGENOMIC PATHWAY Plasma membrane estrogen receptor signaling

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.3 REACTOME A TETRASACCHARIDE LINKER SEQUENCE IS REQUIRED FOR GAG SYNTHESIS Genes involved in A tetrasaccharide linker sequence is required for GAG synthesis
0.0 0.2 REACTOME TRYPTOPHAN CATABOLISM Genes involved in Tryptophan catabolism
0.0 0.2 REACTOME CHOLESTEROL BIOSYNTHESIS Genes involved in Cholesterol biosynthesis