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PRJNA195909:zebrafish embryo and larva development

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Results for msx2a

Z-value: 0.77

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Transcription factors associated with msx2a

Gene Symbol Gene ID Gene Info
ENSDARG00000104651 muscle segment homeobox 2a
ENSDARG00000115813 muscle segment homeobox 2a

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
msx2adr11_v1_chr14_-_24081929_240819290.781.4e-02Click!

Activity profile of msx2a motif

Sorted Z-values of msx2a motif

Promoter Log-likelihood Transcript Gene Gene Info
chr2_-_7666021 2.41 ENSDART00000180007

chr16_-_55028740 2.22 ENSDART00000156368
ENSDART00000161704
zgc:114181
chr14_+_46313396 1.74 ENSDART00000047525
crystallin, beta A1, like 1
chr12_-_25916530 1.20 ENSDART00000186386
synuclein, gamma b (breast cancer-specific protein 1)
chr9_+_53337974 1.06 ENSDART00000145138
dopachrome tautomerase
chr10_-_29900546 1.04 ENSDART00000147441
lens intrinsic membrane protein 2.1
chr25_+_20089986 1.03 ENSDART00000143441
ENSDART00000184073
troponin I4b, tandem duplicate 2
chr15_+_28685625 1.02 ENSDART00000188797
ENSDART00000166036
neuro-oncological ventral antigen 2
chr1_-_38756870 1.00 ENSDART00000130324
ENSDART00000148404
glycoprotein M6Ab
chr13_-_6081803 0.99 ENSDART00000099224
deltaD
chr1_+_52929185 0.98 ENSDART00000147683
inositol polyphosphate-4-phosphatase type II B
chr1_+_10051763 0.94 ENSDART00000011701
fibrinogen beta chain
chr5_-_63515210 0.88 ENSDART00000022348
PR domain containing 12b
chr1_+_53374454 0.85 ENSDART00000038807
uncoupling protein 1
chr6_+_52804267 0.84 ENSDART00000065681
matrilin 4
chr4_+_2252123 0.84 ENSDART00000163996
ENSDART00000066491
GLI pathogenesis-related 1a
chr14_-_498979 0.82 ENSDART00000171976
sprouty homolog 1, antagonist of FGF signaling (Drosophila)
chr25_+_14507567 0.80 ENSDART00000015681
developing brain homeobox 1b
chr5_+_11840905 0.77 ENSDART00000030444
tescalcin a
chr12_+_47663419 0.76 ENSDART00000171932
hematopoietically expressed homeobox
chr6_+_7123980 0.76 ENSDART00000179738
ENSDART00000151311
si:ch211-237c6.4
chr3_-_30941362 0.74 ENSDART00000076830
coronin, actin binding protein, 1A
chr4_-_1324141 0.73 ENSDART00000180720
pleiotrophin
chr24_+_17269849 0.71 ENSDART00000017605
sperm associated antigen 6
chr16_+_10918252 0.70 ENSDART00000172949
POU class 2 homeobox 2a
chr5_+_56268436 0.67 ENSDART00000021159
LIM homeobox 1b
chr2_+_54641644 0.67 ENSDART00000027313
NADH dehydrogenase (ubiquinone) flavoprotein 2
chr4_+_14660769 0.67 ENSDART00000168152
ENSDART00000013990
ENSDART00000079987
ATP-binding cassette, sub-family C (CFTR/MRP), member 9
chr11_+_3989403 0.67 ENSDART00000082379
signal peptidase complex subunit 1
chr21_+_5129513 0.66 ENSDART00000102572
thrombospondin 4b
chr20_+_38032143 0.65 ENSDART00000032161
UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 14 (GalNAc-T14)
chr21_-_16113477 0.65 ENSDART00000147588
cytochrome b561 family, member A3b
chr1_-_35924495 0.64 ENSDART00000184424
SMAD family member 1
chr9_-_32753535 0.63 ENSDART00000060006
oligodendrocyte lineage transcription factor 2
chr1_-_22678471 0.63 ENSDART00000128918
fibroblast growth factor binding protein 1b
chr6_+_25257728 0.62 ENSDART00000162581
kynurenine aminotransferase 3
chr24_+_17270129 0.61 ENSDART00000186729
sperm associated antigen 6
chr16_-_13921589 0.59 ENSDART00000023543
recoverin 2
chr7_-_26408472 0.58 ENSDART00000111494
galactose-3-O-sulfotransferase 4
chr17_+_41992054 0.58 ENSDART00000182878
ENSDART00000111537
kizuna centrosomal protein
chr20_-_53321499 0.58 ENSDART00000179894
ENSDART00000127427
ENSDART00000084952
WAS protein family, member 1
chr23_+_19813677 0.57 ENSDART00000139192
ENSDART00000142308
emerin (Emery-Dreifuss muscular dystrophy)
chr21_+_29077509 0.56 ENSDART00000128561
endothelial cell surface expressed chemotaxis and apoptosis regulator
chr7_+_15872357 0.55 ENSDART00000165757
paired box 6b
chr16_-_26255877 0.54 ENSDART00000146214
Ets2 repressor factor like 1
chr24_-_7699356 0.54 ENSDART00000013117
synaptotagmin Vb
chr6_-_39270851 0.54 ENSDART00000148839
Rho guanine nucleotide exchange factor (GEF) 25b
chr16_-_28878080 0.52 ENSDART00000149501
si:dkey-239n17.4
chr8_-_31062811 0.51 ENSDART00000142528
solute carrier family 20, member 1a
chr2_-_10192459 0.50 ENSDART00000128535
ENSDART00000017173
diencephalon/mesencephalon homeobox 1a
chr21_+_5589923 0.50 ENSDART00000160885
starch binding domain 1
chr13_-_37109987 0.50 ENSDART00000136750
spectrin repeat containing, nuclear envelope 2b
chr8_+_40644838 0.50 ENSDART00000169311
adrenoceptor alpha 2B
chr20_+_38031439 0.50 ENSDART00000153208
UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 14 (GalNAc-T14)
chr20_+_22220988 0.46 ENSDART00000049204
kinase insert domain receptor (a type III receptor tyrosine kinase)
chr10_+_20128267 0.44 ENSDART00000064615
dematin actin binding protein
chr24_+_14713776 0.43 ENSDART00000134475
ganglioside induced differentiation associated protein 1
chr16_+_32238020 0.42 ENSDART00000017562
kelch-like family member 32
chr3_-_50954607 0.42 ENSDART00000163810
CDC42 effector protein (Rho GTPase binding) 4a
chr17_+_43032529 0.42 ENSDART00000055611
ENSDART00000154863
iron-sulfur cluster assembly 2
chr10_-_1788376 0.41 ENSDART00000123842
erythrocyte membrane protein band 4.1 like 4A
chr3_-_58226583 0.41 ENSDART00000187429
im:6904045
chr18_-_35837673 0.40 ENSDART00000059360
heterogeneous nuclear ribonucleoprotein U-like 1
chr17_+_24613255 0.39 ENSDART00000064738
ATP synthase inhibitory factor subunit 1b
chr14_-_4076480 0.39 ENSDART00000059231
ectonucleotide pyrophosphatase/phosphodiesterase 6
chr5_+_36752943 0.38 ENSDART00000017138
exocyst complex component 3-like 2a
chr20_-_9436521 0.37 ENSDART00000133000
zgc:101840
chr5_-_26834511 0.37 ENSDART00000136713
ENSDART00000192932
ENSDART00000113246
si:ch211-102c2.4
chr14_-_1998501 0.36 ENSDART00000189052
protocadherin 2 gamma 5
chr8_-_2230128 0.35 ENSDART00000140427
si:dkeyp-117b11.2
chr4_-_23908802 0.34 ENSDART00000138873
cugbp, Elav-like family member 2
chr22_-_31060579 0.34 ENSDART00000182376
cullin-associated and neddylation-dissociated 2 (putative)
chr3_+_27798094 0.34 ENSDART00000075100
ENSDART00000151437
calcium regulated heat stable protein 1
chr4_-_9557186 0.34 ENSDART00000150569
SH3 and multiple ankyrin repeat domains 3b
chr3_-_35541378 0.34 ENSDART00000183075
ENSDART00000022147
NADH dehydrogenase (ubiquinone) 1, alpha/beta subcomplex, 1b
chr20_-_4738101 0.33 ENSDART00000050201
ENSDART00000152559
ENSDART00000053858
ENSDART00000125620
poly(A) polymerase alpha
chr24_-_38787457 0.33 ENSDART00000112318
ENSDART00000154461
netrin 2
chr2_+_42212948 0.32 ENSDART00000147019
si:ch211-235o23.1
chr7_+_69653981 0.32 ENSDART00000090165
Fras1 related extracellular matrix 1a
chr10_-_20524592 0.32 ENSDART00000185048
DDHD domain containing 2
chr18_-_17485419 0.32 ENSDART00000018764
forkhead box L1
chr4_+_5796761 0.32 ENSDART00000164854
si:ch73-352p4.8
chr15_-_34214440 0.32 ENSDART00000167052
ets variant 1
chr14_+_36869273 0.31 ENSDART00000111674
si:ch211-132p1.2
chr15_-_28094256 0.31 ENSDART00000142041
ENSDART00000132153
ENSDART00000146657
ENSDART00000048720
crystallin, beta A1a
chr7_+_34688527 0.30 ENSDART00000108473
pleckstrin homology domain containing, family G (with RhoGef domain) member 4
chr15_-_22074315 0.30 ENSDART00000149830
dopamine receptor D2a
chr25_+_37126921 0.30 ENSDART00000124331
si:ch1073-174d20.1
chr8_-_34762163 0.30 ENSDART00000114080
SET domain containing 1B, b
chr17_+_21452258 0.29 ENSDART00000157098
phospholipase A2, group IVF, tandem duplicate 1
chr2_-_49985351 0.28 ENSDART00000145888
chemokine (C-C motif) receptor 12a
chr7_+_59169081 0.28 ENSDART00000167980
oligosaccharyltransferase complex subunit
chr5_+_2815021 0.28 ENSDART00000020472
4-hydroxyphenylpyruvate dioxygenase a
chr23_+_16935494 0.27 ENSDART00000143120
si:dkey-147f3.4
chr24_+_17007407 0.27 ENSDART00000110652
zinc finger protein, X-linked
chr13_+_1369003 0.27 ENSDART00000146082
interferon gamma receptor 1
chr24_+_11381400 0.26 ENSDART00000058703
atypical chemokine receptor 4b
chr20_-_38836161 0.26 ENSDART00000061358
si:dkey-221h15.4
chr7_-_49351706 0.26 ENSDART00000174151
BR serine/threonine kinase 2b
chr25_+_35019693 0.25 ENSDART00000046218
filamin C, gamma a (actin binding protein 280)
chr2_-_1569250 0.25 ENSDART00000167202
Dab, reelin signal transducer, homolog 1b (Drosophila)
chr25_+_7784582 0.25 ENSDART00000155016
diacylglycerol kinase, zeta b
chr25_+_7229046 0.25 ENSDART00000149965
ENSDART00000041820
leucine rich repeat and Ig domain containing 1a
chr14_+_597532 0.24 ENSDART00000159805

chr2_+_36701322 0.24 ENSDART00000002510
golgi integral membrane protein 4b
chr6_+_55174744 0.23 ENSDART00000023562
synaptotagmin 2
chr4_-_25271455 0.22 ENSDART00000066936
transmembrane protein 110, like
chr14_-_1987121 0.22 ENSDART00000135733
protocadherin 2 gamma 5
chr10_+_40762200 0.22 ENSDART00000161000
ENSDART00000136185
trace amine associated receptor 19g
chr7_+_34687969 0.22 ENSDART00000182013
ENSDART00000188255
ENSDART00000182728
pleckstrin homology domain containing, family G (with RhoGef domain) member 4
chr10_-_20524387 0.21 ENSDART00000159060
DDHD domain containing 2
chr21_-_39639954 0.21 ENSDART00000026766
aldolase C, fructose-bisphosphate, b
chr5_+_12528693 0.21 ENSDART00000051670
replication factor C (activator 1) 5
chr20_+_9828769 0.21 ENSDART00000160480
ENSDART00000053844
ENSDART00000080691
syntaxin binding protein 6 (amisyn), like
chr25_+_19095231 0.20 ENSDART00000154066
interferon stimulated exonuclease gene
chr1_-_17569793 0.20 ENSDART00000125125
acyl-CoA synthetase long chain family member 1a
chr11_-_2632747 0.19 ENSDART00000008133
si:ch211-160o17.2
chr1_+_8111009 0.19 ENSDART00000152192
si:dkeyp-9d4.5
chr15_-_576135 0.19 ENSDART00000124170
cerebellin 20
chr18_+_13837746 0.19 ENSDART00000169552
cadherin 13, H-cadherin (heart)
chr20_-_27711970 0.19 ENSDART00000139637
zinc finger and BTB domain containing 25
chr1_-_17570013 0.18 ENSDART00000146946
acyl-CoA synthetase long chain family member 1a
chr23_-_39784368 0.18 ENSDART00000110282
si:ch211-286f9.2
chr8_+_10561922 0.18 ENSDART00000133348
family with sequence similarity 19 (chemokine (C-C motif)-like), member A5-like
chr22_+_37631234 0.18 ENSDART00000007346
proteasome 26S subunit, non-ATPase 1
chr11_-_29563437 0.18 ENSDART00000163958
Rho guanine nucleotide exchange factor (GEF) 10-like a
chr10_+_40606084 0.17 ENSDART00000133119
si:ch211-238p8.24
chr23_-_1660708 0.17 ENSDART00000175138

chr5_+_22177033 0.16 ENSDART00000131223
ferredoxin 1b
chr19_-_31584444 0.16 ENSDART00000052183
zgc:111986
chr15_+_8767650 0.16 ENSDART00000033871
adaptor-related protein complex 2, sigma 1 subunit
chr10_-_42751641 0.16 ENSDART00000182734
ENSDART00000113926
zgc:100918
chr17_+_35362851 0.15 ENSDART00000137659
cytidine monophosphate (UMP-CMP) kinase 2, mitochondrial
chr10_+_40700311 0.15 ENSDART00000157650
ENSDART00000138342
trace amine associated receptor 19n
chr6_+_34870374 0.15 ENSDART00000149356
interleukin 23 receptor
chr22_-_28668442 0.15 ENSDART00000182377
collagen, type VIII, alpha 1b
chr13_-_17723417 0.15 ENSDART00000183834
voltage-dependent anion channel 2
chr13_+_40686133 0.15 ENSDART00000146112
Hermansky-Pudlak syndrome 1
chr4_+_2267641 0.15 ENSDART00000165503
si:ch73-89b15.3
chr10_+_40629616 0.14 ENSDART00000147476

chr19_+_43604256 0.14 ENSDART00000151080
ENSDART00000110305
si:ch211-199g17.9
chr21_-_35419486 0.14 ENSDART00000138529
si:dkeyp-23e4.3
chr11_-_165288 0.14 ENSDART00000108703
ENSDART00000173151
testis enhanced gene transcript (BAX inhibitor 1)
chr10_+_40633990 0.14 ENSDART00000190489
ENSDART00000139474
si:ch211-238p8.31
chr9_-_55790458 0.13 ENSDART00000161247
sosondowah ankyrin repeat domain family Ca
chr7_+_34790768 0.13 ENSDART00000075116
si:dkey-148a17.6
chr8_-_38616712 0.13 ENSDART00000141827
si:ch211-198d23.1
chr20_-_35040041 0.13 ENSDART00000131919
kinesin family member 26Bb
chr19_+_43604643 0.12 ENSDART00000151168
si:ch211-199g17.9
chr21_-_21089781 0.12 ENSDART00000144361
ankyrin 1, erythrocytic b
chr9_+_28598577 0.12 ENSDART00000142623
ENSDART00000135947
si:ch73-7i4.1
chr22_+_26853254 0.12 ENSDART00000182487
transmembrane protein 186
chr10_-_5847904 0.11 ENSDART00000161096
ankyrin repeat domain 55
chr10_+_40756352 0.11 ENSDART00000156210
ENSDART00000144576
trace amine associated receptor 19f
chr1_+_58067815 0.11 ENSDART00000156678
si:ch211-114l13.4
chr19_-_10612774 0.11 ENSDART00000091898
si:dkey-211g8.6
chr20_+_26556372 0.11 ENSDART00000187179
ENSDART00000157291
interferon regulatory factor 4b
chr10_-_5847655 0.10 ENSDART00000192773
ankyrin repeat domain 55
chr4_+_77907740 0.10 ENSDART00000172216
si:zfos-2131b9.2
chr2_-_54039293 0.09 ENSDART00000166013
abhydrolase domain containing 8a
chr20_+_45893173 0.09 ENSDART00000131169
bone morphogenetic protein 2b
chr10_-_34870667 0.09 ENSDART00000161272
doublecortin-like kinase 1a
chr14_+_45675306 0.09 ENSDART00000105461
retinal outer segment membrane protein 1b
chr12_-_19007834 0.08 ENSDART00000153248
chondroadherin-like b
chr6_-_7123210 0.08 ENSDART00000041304
autophagy related 3
chr16_+_51326237 0.08 ENSDART00000168525

chr7_-_7493758 0.07 ENSDART00000036703
prefoldin subunit 2
chr10_-_40448736 0.07 ENSDART00000137644
ENSDART00000168190
trace amine associated receptor 20p
chr8_-_16788626 0.07 ENSDART00000191652

chr10_-_40508527 0.07 ENSDART00000121514
ENSDART00000133729
trace amine associated receptor 20b1
chr17_-_11329959 0.07 ENSDART00000015418
interferon regulatory factor 2 binding protein-like
chr4_+_19700308 0.06 ENSDART00000027919
paired box 4
chr3_+_27929505 0.06 ENSDART00000055528
transmembrane protein 114
chr10_-_40474628 0.06 ENSDART00000133892
trace amine associated receptor 20a1
chr7_+_4474880 0.06 ENSDART00000143528
si:dkey-83f18.14
chr22_+_30447969 0.06 ENSDART00000193066
si:dkey-169i5.4
chr10_+_40742685 0.05 ENSDART00000184858
ENSDART00000140300
trace amine associated receptor 19e
chr19_-_24224142 0.05 ENSDART00000136409
ENSDART00000114390
perforin 1.8
chr3_+_28502419 0.05 ENSDART00000151081
septin 12
chr15_-_6966221 0.05 ENSDART00000165487
ENSDART00000027657
mitochondrial ribosomal protein S22
chr21_-_40250500 0.05 ENSDART00000141008
si:ch211-218m3.9
chr10_+_40774215 0.05 ENSDART00000131493
trace amine associated receptor 19b
chr14_-_22385779 0.05 ENSDART00000192211
ENSDART00000175309
F-box and leucine-rich repeat protein 3, like
chr4_-_6459863 0.05 ENSDART00000138367
forkhead box P2
chr1_-_17735861 0.04 ENSDART00000018238
PDZ and LIM domain 3a
chr10_-_40528229 0.04 ENSDART00000146927
ENSDART00000148354
trace amine associated receptor 18g
chr10_+_40726399 0.03 ENSDART00000142812
trace amine associated receptor 19j
chr20_-_35557902 0.03 ENSDART00000134753
adhesion G protein-coupled receptor F7
chr10_+_40583930 0.03 ENSDART00000134523
trace amine associated receptor 18j
chr10_+_40690411 0.03 ENSDART00000146865
trace amine associated receptor 19m
chr15_-_41486793 0.03 ENSDART00000138525
si:ch211-187g4.1
chr15_-_29348212 0.02 ENSDART00000133117
tsukushi small leucine rich proteoglycan homolog (Xenopus laevis)
chr10_-_40443722 0.02 ENSDART00000132906
ENSDART00000157598
trace amine associated receptor 20q
chr20_-_32188897 0.02 ENSDART00000133887
si:ch211-51a19.5
chr17_-_36841981 0.02 ENSDART00000131566
myosin VIb
chr5_+_38752287 0.01 ENSDART00000133571
chemokine (C-X-C motif) ligand 11, duplicate 8
chr20_-_26822522 0.01 ENSDART00000146326
ENSDART00000046764
ENSDART00000103234
ENSDART00000143267
GDP-mannose 4,6-dehydratase
chr24_+_9881219 0.01 ENSDART00000036204
carnitine deficiency-associated gene expressed in ventricle 3
chr7_-_66868543 0.01 ENSDART00000149680
adenosine monophosphate deaminase 3a
chr25_-_18739924 0.01 ENSDART00000156328
si:dkeyp-93a5.2

Network of associatons between targets according to the STRING database.

First level regulatory network of msx2a

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 1.1 GO:2000648 neuroblast division(GO:0055057) positive regulation of stem cell proliferation(GO:2000648)
0.3 0.9 GO:0051574 positive regulation of histone H3-K9 methylation(GO:0051574)
0.3 0.8 GO:0003156 regulation of organ formation(GO:0003156)
0.2 0.6 GO:0021742 abducens nucleus development(GO:0021742)
0.1 1.0 GO:0021523 somatic motor neuron differentiation(GO:0021523)
0.1 0.4 GO:0032780 negative regulation of ATPase activity(GO:0032780)
0.1 0.4 GO:0019695 choline metabolic process(GO:0019695)
0.1 0.3 GO:0010265 SCF complex assembly(GO:0010265)
0.1 0.7 GO:0035989 tendon development(GO:0035989)
0.1 0.8 GO:1990845 adaptive thermogenesis(GO:1990845)
0.1 0.5 GO:0071881 adenylate cyclase-inhibiting adrenergic receptor signaling pathway(GO:0071881)
0.1 0.6 GO:0090104 pancreatic D cell differentiation(GO:0003311) pancreatic epsilon cell differentiation(GO:0090104)
0.1 0.4 GO:0097428 protein maturation by iron-sulfur cluster transfer(GO:0097428)
0.1 0.9 GO:0072378 blood coagulation, fibrin clot formation(GO:0072378)
0.1 0.6 GO:0035479 angioblast cell migration from lateral mesoderm to midline(GO:0035479)
0.1 0.6 GO:0036368 cone photoresponse recovery(GO:0036368)
0.1 0.2 GO:0009211 pyrimidine deoxyribonucleoside triphosphate metabolic process(GO:0009211)
0.1 1.2 GO:0071542 dopaminergic neuron differentiation(GO:0071542)
0.0 0.3 GO:0098815 postsynaptic density assembly(GO:0097107) modulation of excitatory postsynaptic potential(GO:0098815) positive regulation of excitatory postsynaptic potential(GO:2000463)
0.0 0.3 GO:0006572 tyrosine catabolic process(GO:0006572)
0.0 1.0 GO:0051489 regulation of filopodium assembly(GO:0051489)
0.0 0.4 GO:0031272 pseudopodium organization(GO:0031268) pseudopodium assembly(GO:0031269) regulation of pseudopodium assembly(GO:0031272) positive regulation of pseudopodium assembly(GO:0031274)
0.0 0.7 GO:0006120 mitochondrial electron transport, NADH to ubiquinone(GO:0006120)
0.0 0.1 GO:1903232 melanosome assembly(GO:1903232)
0.0 0.2 GO:0097477 spinal cord motor neuron migration(GO:0097476) lateral motor column neuron migration(GO:0097477)
0.0 0.1 GO:0090008 hypoblast development(GO:0090008)
0.0 0.4 GO:0008053 mitochondrial fusion(GO:0008053)
0.0 0.7 GO:0021952 central nervous system projection neuron axonogenesis(GO:0021952)
0.0 0.3 GO:0006465 signal peptide processing(GO:0006465)
0.0 0.2 GO:0046716 muscle cell cellular homeostasis(GO:0046716)
0.0 0.5 GO:0061074 regulation of neural retina development(GO:0061074)
0.0 0.2 GO:0006570 tyrosine metabolic process(GO:0006570)
0.0 0.2 GO:1902262 apoptotic process involved in patterning of blood vessels(GO:1902262)
0.0 0.2 GO:0034650 glucocorticoid biosynthetic process(GO:0006704) cortisol metabolic process(GO:0034650)
0.0 0.3 GO:0051967 negative regulation of cytosolic calcium ion concentration(GO:0051481) negative regulation of synaptic transmission, glutamatergic(GO:0051967)
0.0 0.5 GO:0048791 calcium ion-regulated exocytosis of neurotransmitter(GO:0048791)
0.0 1.0 GO:0003009 skeletal muscle contraction(GO:0003009)
0.0 0.2 GO:0046959 nonassociative learning(GO:0046958) habituation(GO:0046959)
0.0 0.2 GO:0090385 phagosome-lysosome fusion(GO:0090385)
0.0 0.4 GO:0030032 lamellipodium assembly(GO:0030032)
0.0 2.0 GO:0002088 lens development in camera-type eye(GO:0002088)
0.0 0.4 GO:0035338 long-chain fatty-acyl-CoA biosynthetic process(GO:0035338)
0.0 0.3 GO:0070193 synaptonemal complex assembly(GO:0007130) synaptonemal complex organization(GO:0070193)
0.0 0.3 GO:0007198 adenylate cyclase-inhibiting serotonin receptor signaling pathway(GO:0007198)
0.0 0.5 GO:0035924 cellular response to vascular endothelial growth factor stimulus(GO:0035924)
0.0 0.8 GO:0021515 cell differentiation in spinal cord(GO:0021515)
0.0 0.2 GO:0032933 response to sterol depletion(GO:0006991) SREBP signaling pathway(GO:0032933) cellular response to sterol depletion(GO:0071501)
0.0 0.1 GO:0043653 mitochondrial fragmentation involved in apoptotic process(GO:0043653)
0.0 0.3 GO:0098508 endothelial to hematopoietic transition(GO:0098508)
0.0 0.0 GO:0021564 vagus nerve development(GO:0021564)
0.0 0.3 GO:0043631 mRNA polyadenylation(GO:0006378) RNA polyadenylation(GO:0043631)
0.0 0.7 GO:0051781 positive regulation of cell division(GO:0051781)
0.0 0.3 GO:0046475 glycerophospholipid catabolic process(GO:0046475)
0.0 0.3 GO:0051568 histone H3-K4 methylation(GO:0051568)
0.0 0.2 GO:0051127 positive regulation of actin nucleation(GO:0051127) positive regulation of Arp2/3 complex-mediated actin nucleation(GO:2000601)
0.0 0.2 GO:0007205 protein kinase C-activating G-protein coupled receptor signaling pathway(GO:0007205)
0.0 0.9 GO:0000381 regulation of alternative mRNA splicing, via spliceosome(GO:0000381)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 0.9 GO:0005577 fibrinogen complex(GO:0005577)
0.2 0.7 GO:0005787 signal peptidase complex(GO:0005787)
0.1 1.1 GO:0033162 melanosome membrane(GO:0033162) chitosome(GO:0045009)
0.1 1.0 GO:0044295 axonal growth cone(GO:0044295)
0.1 0.2 GO:0034515 proteasome storage granule(GO:0034515)
0.0 0.5 GO:0031045 dense core granule(GO:0031045)
0.0 0.1 GO:0031085 BLOC-3 complex(GO:0031085)
0.0 0.6 GO:0071144 SMAD2-SMAD3 protein complex(GO:0071144)
0.0 1.2 GO:0043679 axon terminus(GO:0043679)
0.0 0.2 GO:0005663 DNA replication factor C complex(GO:0005663)
0.0 1.0 GO:0005861 troponin complex(GO:0005861)
0.0 1.0 GO:0045271 mitochondrial respiratory chain complex I(GO:0005747) NADH dehydrogenase complex(GO:0030964) respiratory chain complex I(GO:0045271)
0.0 0.6 GO:0000145 exocyst(GO:0000145)
0.0 0.3 GO:0008250 oligosaccharyltransferase complex(GO:0008250)
0.0 0.2 GO:0031307 integral component of mitochondrial outer membrane(GO:0031307)
0.0 0.2 GO:0030122 AP-2 adaptor complex(GO:0030122)
0.0 0.3 GO:0048188 Set1C/COMPASS complex(GO:0048188)
0.0 0.3 GO:0000795 synaptonemal complex(GO:0000795)
0.0 0.2 GO:0031209 SCAR complex(GO:0031209)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 1.2 GO:1903136 cuprous ion binding(GO:1903136)
0.3 0.9 GO:1990226 histone methyltransferase binding(GO:1990226)
0.2 2.2 GO:0016805 dipeptidase activity(GO:0016805)
0.2 0.8 GO:0017077 oxidative phosphorylation uncoupler activity(GO:0017077)
0.2 1.1 GO:0016863 intramolecular oxidoreductase activity, transposing C=C bonds(GO:0016863)
0.1 1.0 GO:0016316 phosphatidylinositol-3,4-bisphosphate 4-phosphatase activity(GO:0016316)
0.1 0.7 GO:0008281 sulfonylurea receptor activity(GO:0008281)
0.1 0.3 GO:0000035 acyl binding(GO:0000035)
0.1 0.5 GO:2001070 starch binding(GO:2001070)
0.1 0.3 GO:0003868 4-hydroxyphenylpyruvate dioxygenase activity(GO:0003868)
0.1 0.5 GO:0004938 alpha2-adrenergic receptor activity(GO:0004938)
0.1 0.3 GO:0004652 polynucleotide adenylyltransferase activity(GO:0004652)
0.1 0.4 GO:0042030 ATPase inhibitor activity(GO:0042030)
0.1 0.6 GO:0001733 galactosylceramide sulfotransferase activity(GO:0001733) galactose 3-O-sulfotransferase activity(GO:0050694)
0.1 0.2 GO:0009041 uridylate kinase activity(GO:0009041)
0.0 0.3 GO:0030160 GKAP/Homer scaffold activity(GO:0030160)
0.0 1.0 GO:0005112 Notch binding(GO:0005112)
0.0 3.1 GO:0005212 structural constituent of eye lens(GO:0005212)
0.0 0.5 GO:0005021 vascular endothelial growth factor-activated receptor activity(GO:0005021)
0.0 1.3 GO:0051537 2 iron, 2 sulfur cluster binding(GO:0051537)
0.0 0.4 GO:0047676 arachidonate-CoA ligase activity(GO:0047676)
0.0 0.5 GO:0005315 inorganic phosphate transmembrane transporter activity(GO:0005315)
0.0 0.6 GO:0070411 I-SMAD binding(GO:0070411)
0.0 0.2 GO:0016312 inositol bisphosphate phosphatase activity(GO:0016312)
0.0 0.1 GO:0015288 porin activity(GO:0015288)
0.0 0.1 GO:0019777 Atg12 transferase activity(GO:0019777)
0.0 0.2 GO:0004332 fructose-bisphosphate aldolase activity(GO:0004332)
0.0 0.3 GO:0047498 calcium-dependent phospholipase A2 activity(GO:0047498)
0.0 0.1 GO:0004104 cholinesterase activity(GO:0004104)
0.0 0.5 GO:0004806 triglyceride lipase activity(GO:0004806)
0.0 0.3 GO:0001591 dopamine neurotransmitter receptor activity, coupled via Gi/Go(GO:0001591)
0.0 0.2 GO:0033170 DNA clamp loader activity(GO:0003689) protein-DNA loading ATPase activity(GO:0033170)
0.0 0.2 GO:0071933 Arp2/3 complex binding(GO:0071933)
0.0 0.5 GO:0019957 C-C chemokine binding(GO:0019957)
0.0 0.3 GO:0043176 amine binding(GO:0043176) serotonin binding(GO:0051378)
0.0 0.3 GO:0050321 tau-protein kinase activity(GO:0050321)
0.0 0.5 GO:0001786 phosphatidylserine binding(GO:0001786)
0.0 0.2 GO:0004143 diacylglycerol kinase activity(GO:0004143)
0.0 0.2 GO:0005154 epidermal growth factor receptor binding(GO:0005154)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.5 PID VEGF VEGFR PATHWAY VEGF and VEGFR signaling network
0.1 0.9 PID INTEGRIN2 PATHWAY Beta2 integrin cell surface interactions
0.1 0.3 ST INTERFERON GAMMA PATHWAY Interferon gamma pathway.
0.0 0.6 PID ALK2 PATHWAY ALK2 signaling events
0.0 0.7 PID SYNDECAN 3 PATHWAY Syndecan-3-mediated signaling events
0.0 0.3 PID THROMBIN PAR4 PATHWAY PAR4-mediated thrombin signaling events
0.0 0.6 SIG REGULATION OF THE ACTIN CYTOSKELETON BY RHO GTPASES Genes related to regulation of the actin cytoskeleton
0.0 0.3 PID P38 MK2 PATHWAY p38 signaling mediated by MAPKAP kinases
0.0 1.0 ST JNK MAPK PATHWAY JNK MAPK Pathway

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.0 REACTOME REGULATION OF PYRUVATE DEHYDROGENASE PDH COMPLEX Genes involved in Regulation of pyruvate dehydrogenase (PDH) complex
0.1 0.9 REACTOME COMMON PATHWAY Genes involved in Common Pathway
0.1 0.5 REACTOME VEGF LIGAND RECEPTOR INTERACTIONS Genes involved in VEGF ligand-receptor interactions
0.1 0.7 REACTOME SYNTHESIS SECRETION AND INACTIVATION OF GLP1 Genes involved in Synthesis, Secretion, and Inactivation of Glucagon-like Peptide-1 (GLP-1)
0.0 0.6 REACTOME SIGNALING BY BMP Genes involved in Signaling by BMP
0.0 0.5 REACTOME AMINE LIGAND BINDING RECEPTORS Genes involved in Amine ligand-binding receptors
0.0 0.3 REACTOME REGULATION OF IFNG SIGNALING Genes involved in Regulation of IFNG signaling
0.0 1.0 REACTOME EGFR DOWNREGULATION Genes involved in EGFR downregulation
0.0 0.6 REACTOME SYNTHESIS OF PIPS AT THE EARLY ENDOSOME MEMBRANE Genes involved in Synthesis of PIPs at the early endosome membrane
0.0 1.2 REACTOME O LINKED GLYCOSYLATION OF MUCINS Genes involved in O-linked glycosylation of mucins
0.0 0.7 REACTOME ABC FAMILY PROTEINS MEDIATED TRANSPORT Genes involved in ABC-family proteins mediated transport
0.0 1.5 REACTOME RESPIRATORY ELECTRON TRANSPORT ATP SYNTHESIS BY CHEMIOSMOTIC COUPLING AND HEAT PRODUCTION BY UNCOUPLING PROTEINS Genes involved in Respiratory electron transport, ATP synthesis by chemiosmotic coupling, and heat production by uncoupling proteins.
0.0 0.3 REACTOME PROCESSING OF INTRONLESS PRE MRNAS Genes involved in Processing of Intronless Pre-mRNAs
0.0 0.2 REACTOME BOTULINUM NEUROTOXICITY Genes involved in Botulinum neurotoxicity
0.0 0.3 REACTOME THROMBIN SIGNALLING THROUGH PROTEINASE ACTIVATED RECEPTORS PARS Genes involved in Thrombin signalling through proteinase activated receptors (PARs)
0.0 0.2 REACTOME POL SWITCHING Genes involved in Polymerase switching