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PRJNA195909:zebrafish embryo and larva development

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Results for meox2b

Z-value: 0.72

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Transcription factors associated with meox2b

Gene Symbol Gene ID Gene Info
ENSDARG00000061818 mesenchyme homeobox 2b
ENSDARG00000116206 mesenchyme homeobox 2b

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
meox2bdr11_v1_chr19_+_31183495_311834950.383.1e-01Click!

Activity profile of meox2b motif

Sorted Z-values of meox2b motif

Promoter Log-likelihood Transcript Gene Gene Info
chr25_+_14507567 1.56 ENSDART00000015681
developing brain homeobox 1b
chr23_-_23401305 1.39 ENSDART00000078936
hairy-related 9
chr16_+_23431189 1.38 ENSDART00000004679
ictacalcin
chr16_+_23913943 1.37 ENSDART00000175404
ENSDART00000129525
apolipoprotein A-IV b, tandem duplicate 1
chr3_+_30922947 1.34 ENSDART00000184060
claudin i
chr8_+_21353878 1.00 ENSDART00000056420
aminolevulinate, delta-, synthase 2
chr17_+_15433671 0.99 ENSDART00000149568
fatty acid binding protein 7, brain, a
chr25_+_31276842 0.98 ENSDART00000187238
troponin I type 2a (skeletal, fast), tandem duplicate 4
chr10_+_39084354 0.97 ENSDART00000158245
si:ch73-1a9.3
chr15_+_46356879 0.95 ENSDART00000154388
wu:fb18f06
chr20_+_2281933 0.92 ENSDART00000137579
si:ch73-18b11.2
chr17_+_15433518 0.91 ENSDART00000026180
fatty acid binding protein 7, brain, a
chr12_-_35830625 0.88 ENSDART00000180028

chr3_-_25814097 0.84 ENSDART00000169706
netrin 1b
chr25_-_31423493 0.83 ENSDART00000027661
myogenic differentiation 1
chr1_+_52392511 0.83 ENSDART00000144025
si:ch211-217k17.8
chr12_+_27117609 0.80 ENSDART00000076154
homeobox B8b
chr14_+_45406299 0.79 ENSDART00000173142
ENSDART00000112377
microtubule-associated protein 1 light chain 3 gamma, like
chr13_+_25449681 0.79 ENSDART00000101328
atonal bHLH transcription factor 7
chr15_-_21877726 0.78 ENSDART00000127819
ENSDART00000145646
ENSDART00000100897
ENSDART00000144739
zgc:162608
chr7_-_25895189 0.78 ENSDART00000173599
ENSDART00000079235
ENSDART00000173786
ENSDART00000173602
ENSDART00000079245
ENSDART00000187568
ENSDART00000173505
CD99 molecule-like 2
chr6_+_15268685 0.78 ENSDART00000128090
ENSDART00000154417
esophageal cancer related gene 4b
chr3_+_46635527 0.77 ENSDART00000153971
si:dkey-248g21.1
chr24_-_21923930 0.74 ENSDART00000131944
transgelin 3b
chr7_-_2039060 0.74 ENSDART00000173879
si:cabz01007794.1
chr2_+_27010439 0.72 ENSDART00000030547
cadherin 7a
chr16_+_5774977 0.72 ENSDART00000134202
cholecystokinin a
chr19_-_42607451 0.72 ENSDART00000004392
FK506 binding protein 9
chr24_+_17269849 0.71 ENSDART00000017605
sperm associated antigen 6
chr3_+_28953274 0.70 ENSDART00000133528
ENSDART00000103602
lectin, galactoside-binding, soluble, 2a
chr4_-_2545310 0.70 ENSDART00000150619
ENSDART00000140760
E2F transcription factor 7
chr16_-_24044664 0.70 ENSDART00000136982
basal cell adhesion molecule (Lutheran blood group)
chr12_+_20352400 0.70 ENSDART00000066383
hemoglobin, alpha embryonic 5
chr11_-_45138857 0.69 ENSDART00000166501
calcium activated nucleotidase 1b
chr15_+_23799461 0.69 ENSDART00000154885
si:ch211-167j9.4
chr10_-_24391716 0.68 ENSDART00000141332
ENSDART00000100772
solute carrier family 43 (amino acid system L transporter), member 2b
chr17_-_14876758 0.68 ENSDART00000155857
nidogen 2a (osteonidogen)
chr11_-_1509773 0.68 ENSDART00000050762
phosphatase and actin regulator 3b
chr4_+_12615836 0.68 ENSDART00000003583
LIM domain only 3
chr9_-_33107237 0.67 ENSDART00000013918
calsequestrin 2
chr22_-_10459880 0.67 ENSDART00000064801
osteoglycin
chr1_-_45049603 0.65 ENSDART00000023336
ribosomal protein S6
chr11_+_3254524 0.64 ENSDART00000159459
premelanosome protein a
chr16_+_23961276 0.64 ENSDART00000192754
apolipoprotein Eb
chr10_+_42358426 0.64 ENSDART00000025691
drebrin-like a
chr24_+_5237753 0.63 ENSDART00000106488
ENSDART00000005901
procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2
chr18_-_33979693 0.63 ENSDART00000021215
si:ch211-203b20.7
chr21_-_37973819 0.62 ENSDART00000133405
ripply transcriptional repressor 1
chr5_-_41307550 0.62 ENSDART00000143446
natriuretic peptide receptor 3
chr19_+_12915498 0.62 ENSDART00000132892
collagen triple helix repeat containing 1a
chr13_+_30903816 0.62 ENSDART00000191727
excision repair cross-complementation group 6
chr25_+_29160102 0.62 ENSDART00000162854
pyruvate kinase M1/2b
chr7_+_20503344 0.61 ENSDART00000157699
si:dkey-19b23.12
chr16_-_7443388 0.61 ENSDART00000017445
PR domain containing 1a, with ZNF domain
chr22_-_15593824 0.61 ENSDART00000123125
tropomyosin 4a
chr22_+_16535575 0.61 ENSDART00000083063
T-cell acute lymphocytic leukemia 1
chr4_+_14900042 0.59 ENSDART00000018261
aldo-keto reductase family 1, member B1 (aldose reductase)
chr21_+_28445052 0.59 ENSDART00000077871
phosphorylase, glycogen, muscle A
chr23_+_42482137 0.59 ENSDART00000160199
cytochrome P450, family 2, subfamily AA, polypeptide 3
chr14_-_4273396 0.59 ENSDART00000127318
FERM and PDZ domain containing 1b
chr11_+_44135351 0.58 ENSDART00000182914

chr18_+_29402623 0.56 ENSDART00000014703
v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog a (paralog a)
chr17_+_23298928 0.56 ENSDART00000153652
zgc:165461
chr11_+_14199802 0.55 ENSDART00000102520
ENSDART00000133172
paralemmin 1a
chr9_-_21918963 0.55 ENSDART00000090782
LIM domain 7a
chr24_-_39610585 0.54 ENSDART00000066506
cytochrome c oxidase subunit VIb polypeptide 1
chr6_-_54826061 0.54 ENSDART00000149982
troponin I type 1b (skeletal, slow)
chr14_-_3381303 0.54 ENSDART00000171601
im:7150988
chr2_-_23172708 0.54 ENSDART00000041365
paired related homeobox 1a
chr16_+_1353894 0.54 ENSDART00000148426
cugbp, Elav-like family member 3b
chr7_-_48667056 0.54 ENSDART00000006378
cyclin-dependent kinase inhibitor 1Ca
chr23_+_20110086 0.54 ENSDART00000054664
troponin C type 1b (slow)
chr12_-_5728755 0.53 ENSDART00000105887
distal-less homeobox 4b
chr2_-_10703621 0.53 ENSDART00000005944
ribosomal protein L5a
chr16_+_23984179 0.53 ENSDART00000175879
apolipoprotein C-II
chr16_-_45235947 0.53 ENSDART00000164436
si:dkey-33i11.4
chr11_+_8565323 0.52 ENSDART00000081607
ENSDART00000141612
transducin (beta)-like 1 X-linked receptor 1a
chr13_+_27232848 0.52 ENSDART00000138043
Ras and Rab interactor 2
chr1_-_58036509 0.52 ENSDART00000081122
si:ch211-114l13.7
chr15_+_19652807 0.51 ENSDART00000134321
ENSDART00000054426
lens intrinsic membrane protein 2.3
chr13_+_33282095 0.51 ENSDART00000135200
coiled-coil domain containing 28B
chr24_-_6078222 0.51 ENSDART00000146830
amyloid beta (A4) precursor protein-binding, family B, member 1 interacting protein
chr12_-_10409961 0.50 ENSDART00000149521
ENSDART00000052001
eukaryotic elongation factor 2 kinase
chr15_-_28596507 0.50 ENSDART00000156800
si:ch211-225b7.5
chr8_-_19216657 0.50 ENSDART00000135096
ENSDART00000135869
ENSDART00000145951
si:ch73-222f22.2
si:ch73-222f22.2
chr9_+_31282161 0.50 ENSDART00000010774
zic family member 2 (odd-paired homolog, Drosophila), a
chr23_+_43489182 0.50 ENSDART00000162062
zinc finger protein 341
chr19_-_41069573 0.50 ENSDART00000111982
ENSDART00000193142
sarcoglycan, epsilon
chr9_-_18911608 0.49 ENSDART00000138785
si:dkey-239h2.3
chr1_-_54063520 0.49 ENSDART00000171722
single-pass membrane protein with aspartate-rich tail 1b
chr4_+_9669717 0.49 ENSDART00000004604
si:dkey-153k10.9
chr18_-_19456269 0.49 ENSDART00000060363
ribosomal protein L4
chr14_-_21064199 0.49 ENSDART00000172099
si:dkey-74k8.3
chr11_-_30158191 0.49 ENSDART00000155278
ENSDART00000156121
Scm polycomb group protein like 2
chr1_-_45633955 0.49 ENSDART00000044057
septin 3
chr19_+_43297546 0.48 ENSDART00000168002
lysosomal protein transmembrane 5
chr20_+_539852 0.48 ENSDART00000185994
dermatan sulfate epimerase
chr21_+_28958471 0.48 ENSDART00000144331
ENSDART00000005929
protein phosphatase 3, catalytic subunit, alpha isozyme
chr11_-_41853874 0.48 ENSDART00000002556
MRT4 homolog, ribosome maturation factor
chr17_-_25649079 0.48 ENSDART00000130955
protein phosphatase 1, catalytic subunit, beta isozyme
chr21_-_5205617 0.48 ENSDART00000145554
ENSDART00000045284
ribosomal protein L37
chr7_+_34290051 0.48 ENSDART00000123498
fin bud initiation factor b
chr7_-_24699985 0.48 ENSDART00000052802
calbindin 2b
chr23_+_19813677 0.47 ENSDART00000139192
ENSDART00000142308
emerin (Emery-Dreifuss muscular dystrophy)
chr24_+_9744012 0.47 ENSDART00000129656
transmembrane protein 108
chr1_+_52929185 0.47 ENSDART00000147683
inositol polyphosphate-4-phosphatase type II B
chr21_+_27416284 0.47 ENSDART00000077593
ENSDART00000108763
complement factor B
chr6_+_47424266 0.47 ENSDART00000171087
si:ch211-286o17.1
chr3_-_23643751 0.46 ENSDART00000078425
ENSDART00000140264
even-skipped-like1
chr4_+_12612145 0.46 ENSDART00000181201
LIM domain only 3
chr4_-_16341801 0.46 ENSDART00000140190
keratocan
chr7_-_54679595 0.46 ENSDART00000165320
cyclin D1
chr16_+_33655890 0.46 ENSDART00000143757
four and a half LIM domains 3a
chr3_+_18398876 0.46 ENSDART00000141100
ENSDART00000138107
ribosomal protein S2
chr23_+_36095260 0.46 ENSDART00000127384
homeobox C9a
chr14_+_3287740 0.46 ENSDART00000186290
caudal type homeobox 1a
chr15_-_47865063 0.45 ENSDART00000151600
H3 histone, family 3B.1
chr1_-_40911332 0.45 ENSDART00000027463
H6 family homeobox 4
chr20_+_6659770 0.45 ENSDART00000192135
tensin 3, tandem duplicate 2
chr16_+_50972803 0.45 ENSDART00000178189
si:dkeyp-97a10.2
chr9_+_25776971 0.45 ENSDART00000146011
zinc finger E-box binding homeobox 2a
chr15_-_22074315 0.45 ENSDART00000149830
dopamine receptor D2a
chr20_-_40370736 0.45 ENSDART00000041229
fatty acid binding protein 7, brain, b
chr17_+_21295132 0.45 ENSDART00000103845
enolase family member 4
chr1_+_34696503 0.44 ENSDART00000186106

chr16_+_46111849 0.44 ENSDART00000172232
synaptic vesicle glycoprotein 2A
chr13_-_31296358 0.44 ENSDART00000030946
PR domain containing 8
chr16_-_42933332 0.44 ENSDART00000057305
thrombospondin 3a
chr2_-_33993533 0.44 ENSDART00000140910
ENSDART00000077304
patched 2
chr11_-_6048490 0.44 ENSDART00000066164
plasmalemma vesicle associated protein b
chr3_-_30685401 0.44 ENSDART00000151097
si:ch211-51c14.1
chr24_-_25691020 0.44 ENSDART00000015391
cholinergic receptor, nicotinic, delta (muscle)
chr1_+_12767318 0.44 ENSDART00000162652
protocadherin 10a
chr13_-_31470439 0.43 ENSDART00000076574
reticulon 1a
chr11_+_2198831 0.43 ENSDART00000160515
homeobox C6b
chr2_-_30668580 0.43 ENSDART00000087270
catenin (cadherin-associated protein), delta 2b
chr10_-_3295197 0.43 ENSDART00000109131
slc25a1 solute carrier family 25 (mitochondrial carrier; citrate transporter), member 1b
chr20_-_45812144 0.43 ENSDART00000147897
ENSDART00000147637
fermitin family member 1
chr9_-_12424791 0.42 ENSDART00000135447
ENSDART00000088199
zgc:162707
chr7_-_58130703 0.42 ENSDART00000172082
ankyrin 2b, neuronal
chr5_+_23242370 0.42 ENSDART00000051532
angiotensin II receptor, type 2
chr23_+_11285662 0.42 ENSDART00000111028
cell adhesion molecule L1-like a
chr16_+_16969060 0.42 ENSDART00000182819
ENSDART00000191876
si:ch211-120k19.1
ribosomal protein L18
chr2_-_32356539 0.42 ENSDART00000169316
ArfGAP with SH3 domain, ankyrin repeat and PH domain 1a
chr23_+_28731379 0.42 ENSDART00000047378
cortistatin
chr24_+_21621654 0.41 ENSDART00000002595
ribosomal protein L21
chr20_-_27225876 0.41 ENSDART00000149204
ENSDART00000149732
si:dkey-85n7.7
chr21_-_22827548 0.41 ENSDART00000079161
angiopoietin-like 5
chr21_-_26495700 0.41 ENSDART00000109379
CD248 molecule, endosialin b
chr8_+_28259347 0.41 ENSDART00000110857
family with sequence similarity 212, member B
chr15_+_36309070 0.40 ENSDART00000157034
geminin coiled-coil domain containing
chr22_+_12770877 0.40 ENSDART00000044683
formimidoyltransferase cyclodeaminase
chr20_+_15015557 0.40 ENSDART00000039345
myocilin
chr5_+_27897504 0.40 ENSDART00000130936
ADAM metallopeptidase domain 28
chr4_+_43522680 0.40 ENSDART00000182252
si:dkeyp-53e4.4
chr6_+_52804267 0.40 ENSDART00000065681
matrilin 4
chr16_+_40576679 0.40 ENSDART00000169412
ENSDART00000193464
cyclin E2
chr25_+_31868268 0.39 ENSDART00000022325
poly (ADP-ribose) polymerase family, member 16
chr24_+_9412450 0.39 ENSDART00000132724
si:ch211-285f17.1
chr16_-_28878080 0.39 ENSDART00000149501
si:dkey-239n17.4
chr17_+_24687338 0.39 ENSDART00000135794
selenoprotein N
chr13_+_35339182 0.39 ENSDART00000019323
jagged 1b
chr5_-_48268049 0.39 ENSDART00000187454
myocyte enhancer factor 2cb
chr18_+_40355408 0.39 ENSDART00000167134
sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6D, like
chr20_-_7072487 0.39 ENSDART00000145954
si:ch211-121a2.2
chr13_+_255067 0.38 ENSDART00000102505
forkhead box G1d
chr21_-_37194365 0.38 ENSDART00000100286
fibroblast growth factor receptor 4
chr5_-_20205075 0.38 ENSDART00000051611
D-amino-acid oxidase, tandem duplicate 3
chr14_-_17072736 0.38 ENSDART00000106333
paired-like homeobox 2bb
chr12_+_24952902 0.38 ENSDART00000189086
ENSDART00000014868
calmodulin 3a (phosphorylase kinase, delta)
chr21_-_25604603 0.38 ENSDART00000133134
ENSDART00000139460
EGF containing fibulin extracellular matrix protein 2b
chr7_-_12968689 0.38 ENSDART00000173115
ENSDART00000013690
ribosomal protein, large P2, like
chr7_-_28148310 0.38 ENSDART00000044208
LIM domain only 1
chr21_-_19314618 0.37 ENSDART00000188744
glycerol-3-phosphate acyltransferase 3
chr21_+_20383837 0.37 ENSDART00000026430
heat shock protein, alpha-crystallin-related, b11
chr12_+_8168272 0.37 ENSDART00000054092
AT-rich interaction domain 5B
chr3_-_60175470 0.37 ENSDART00000156597
si:ch73-364h19.1
chr1_+_54865552 0.37 ENSDART00000145381
si:ch211-196h16.5
chr21_+_19062124 0.37 ENSDART00000134746
ribosomal protein L17
chr24_+_22485710 0.36 ENSDART00000146058
si:dkey-40h20.1
chr16_+_31804590 0.36 ENSDART00000167321
wingless-type MMTV integration site family, member 4b
chr18_+_3037998 0.36 ENSDART00000185844
ENSDART00000162657
ribosomal protein S3
chr13_+_7442023 0.36 ENSDART00000080975
tumor necrosis factor, alpha-induced protein 2b
chr24_-_40860603 0.36 ENSDART00000188032

chr6_-_39270851 0.36 ENSDART00000148839
Rho guanine nucleotide exchange factor (GEF) 25b
chr4_+_391297 0.36 ENSDART00000030215
ribosomal protein L18a
chr24_-_4450238 0.36 ENSDART00000066835
frizzled class receptor 8a
chr7_+_69019851 0.35 ENSDART00000162891

chr7_-_38792543 0.35 ENSDART00000157416
si:dkey-23n7.10
chr15_+_7086327 0.35 ENSDART00000114560
phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit beta
chr15_-_14212777 0.35 ENSDART00000165572

chr4_+_58576146 0.35 ENSDART00000164911
si:ch211-212k5.4
chr18_+_30028135 0.35 ENSDART00000140825
ENSDART00000145306
ENSDART00000136810
si:ch211-220f16.1
chr20_+_4060839 0.35 ENSDART00000178565
tripartite motif containing 67
chr23_+_31107685 0.35 ENSDART00000103448
T-box 18
chr3_+_17537352 0.34 ENSDART00000104549
hypocretin (orexin) neuropeptide precursor
chr25_+_35553542 0.34 ENSDART00000113723
Spi-1 proto-oncogene a
chr16_+_16968682 0.34 ENSDART00000111074
si:ch211-120k19.1
chr11_+_30244356 0.34 ENSDART00000036050
ENSDART00000150080
retinoschisin 1a
chr14_+_41345175 0.34 ENSDART00000086104
NADPH oxidase 1

Network of associatons between targets according to the STRING database.

First level regulatory network of meox2b

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.0 GO:0070314 G1 to G0 transition(GO:0070314)
0.3 0.8 GO:0021960 anterior commissure morphogenesis(GO:0021960)
0.3 0.8 GO:0002074 extraocular skeletal muscle development(GO:0002074)
0.2 0.6 GO:0097435 fibril organization(GO:0097435)
0.2 0.6 GO:0034382 chylomicron remnant clearance(GO:0034382) triglyceride-rich lipoprotein particle clearance(GO:0071830) intermediate-density lipoprotein particle clearance(GO:0071831)
0.2 0.6 GO:0045601 regulation of endothelial cell differentiation(GO:0045601)
0.2 0.6 GO:0052575 carbohydrate localization(GO:0052575) carbohydrate storage(GO:0052576)
0.2 0.5 GO:0009912 auditory receptor cell fate commitment(GO:0009912) inner ear receptor cell fate commitment(GO:0060120)
0.2 0.5 GO:0060898 eye field cell fate commitment involved in camera-type eye formation(GO:0060898)
0.2 0.7 GO:0010882 regulation of cardiac muscle contraction by calcium ion signaling(GO:0010882)
0.2 0.6 GO:0017185 peptidyl-lysine hydroxylation(GO:0017185)
0.2 0.8 GO:0034380 regulation of cholesterol esterification(GO:0010872) positive regulation of cholesterol esterification(GO:0010873) high-density lipoprotein particle assembly(GO:0034380)
0.1 0.7 GO:0042023 regulation of DNA endoreduplication(GO:0032875) positive regulation of DNA endoreduplication(GO:0032877) DNA endoreduplication(GO:0042023)
0.1 0.4 GO:0015942 formate metabolic process(GO:0015942) histidine catabolic process to glutamate and formamide(GO:0019556) histidine catabolic process to glutamate and formate(GO:0019557) formamide metabolic process(GO:0043606)
0.1 0.4 GO:0070857 regulation of bile acid biosynthetic process(GO:0070857) regulation of bile acid metabolic process(GO:1904251)
0.1 0.5 GO:0034434 steroid esterification(GO:0034433) sterol esterification(GO:0034434) cholesterol esterification(GO:0034435)
0.1 0.5 GO:1900271 regulation of presynaptic cytosolic calcium ion concentration(GO:0099509) regulation of long-term synaptic potentiation(GO:1900271)
0.1 0.5 GO:1901492 positive regulation of lymphangiogenesis(GO:1901492)
0.1 0.8 GO:0033278 cell proliferation in midbrain(GO:0033278)
0.1 0.4 GO:0006843 mitochondrial citrate transport(GO:0006843)
0.1 0.3 GO:0006145 purine nucleobase catabolic process(GO:0006145)
0.1 0.5 GO:0071480 response to gamma radiation(GO:0010332) cellular response to gamma radiation(GO:0071480)
0.1 0.5 GO:0030205 dermatan sulfate metabolic process(GO:0030205)
0.1 0.4 GO:0009080 alanine metabolic process(GO:0006522) alanine catabolic process(GO:0006524) pyruvate family amino acid metabolic process(GO:0009078) pyruvate family amino acid catabolic process(GO:0009080) D-alanine family amino acid metabolic process(GO:0046144) D-alanine metabolic process(GO:0046436) D-alanine catabolic process(GO:0055130)
0.1 0.5 GO:0098974 postsynaptic actin cytoskeleton organization(GO:0098974)
0.1 0.4 GO:0061549 sympathetic ganglion development(GO:0061549)
0.1 0.5 GO:0031571 mitotic G1 DNA damage checkpoint(GO:0031571)
0.1 0.6 GO:0006283 transcription-coupled nucleotide-excision repair(GO:0006283)
0.1 0.3 GO:0098923 retrograde trans-synaptic signaling by soluble gas(GO:0098923) retrograde trans-synaptic signaling by nitric oxide(GO:0098924)
0.1 0.4 GO:0060231 mesenchymal to epithelial transition(GO:0060231)
0.1 0.3 GO:0042755 eating behavior(GO:0042755)
0.1 0.4 GO:0036371 protein localization to T-tubule(GO:0036371)
0.1 0.2 GO:0098801 renal system process involved in regulation of blood volume(GO:0001977) renal system process involved in regulation of systemic arterial blood pressure(GO:0003071) regulation of glomerular filtration(GO:0003093) regulation of renal system process(GO:0098801)
0.1 0.2 GO:0007414 axonal defasciculation(GO:0007414)
0.1 0.4 GO:1903251 multi-ciliated epithelial cell differentiation(GO:1903251)
0.1 0.2 GO:1901890 positive regulation of cell junction assembly(GO:1901890)
0.1 0.5 GO:1904030 negative regulation of cyclin-dependent protein serine/threonine kinase activity(GO:0045736) negative regulation of cyclin-dependent protein kinase activity(GO:1904030)
0.1 0.3 GO:0060467 negative regulation of fertilization(GO:0060467) prevention of polyspermy(GO:0060468) cortical granule exocytosis(GO:0060471)
0.1 0.3 GO:0009098 leucine biosynthetic process(GO:0009098)
0.1 0.3 GO:0000448 cleavage in ITS2 between 5.8S rRNA and LSU-rRNA of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000448)
0.1 0.3 GO:0033363 secretory granule organization(GO:0033363) platelet dense granule organization(GO:0060155)
0.1 0.4 GO:0009954 proximal/distal pattern formation(GO:0009954)
0.1 0.2 GO:0032757 interleukin-8 production(GO:0032637) regulation of interleukin-8 production(GO:0032677) positive regulation of interleukin-8 production(GO:0032757)
0.1 0.2 GO:0010159 specification of organ position(GO:0010159)
0.1 0.6 GO:0001709 cell fate determination(GO:0001709)
0.1 0.6 GO:0061075 positive regulation of neural retina development(GO:0061075) positive regulation of retina development in camera-type eye(GO:1902868)
0.1 0.3 GO:0006521 regulation of cellular amino acid metabolic process(GO:0006521) microglia development(GO:0014005) regulation of cellular amine metabolic process(GO:0033238)
0.1 0.4 GO:0090243 fibroblast growth factor receptor signaling pathway involved in somitogenesis(GO:0090243)
0.1 0.5 GO:0032889 regulation of vacuole fusion, non-autophagic(GO:0032889)
0.1 0.2 GO:0044038 cell wall biogenesis(GO:0042546) cell wall macromolecule biosynthetic process(GO:0044038) cellular component macromolecule biosynthetic process(GO:0070589)
0.1 3.0 GO:0060048 cardiac muscle contraction(GO:0060048)
0.1 0.5 GO:0086002 cardiac muscle cell action potential involved in contraction(GO:0086002)
0.1 0.3 GO:0061337 cardiac conduction(GO:0061337)
0.1 0.2 GO:0030043 actin filament fragmentation(GO:0030043)
0.1 0.3 GO:0060055 larval development(GO:0002164) larval heart development(GO:0007508) angiogenesis involved in wound healing(GO:0060055)
0.1 0.5 GO:0097106 postsynaptic density organization(GO:0097106)
0.1 0.2 GO:0036159 inner dynein arm assembly(GO:0036159)
0.1 0.4 GO:0042984 amyloid precursor protein biosynthetic process(GO:0042983) regulation of amyloid precursor protein biosynthetic process(GO:0042984)
0.1 0.4 GO:0050848 regulation of calcium-mediated signaling(GO:0050848)
0.1 0.3 GO:0006562 proline catabolic process(GO:0006562) proline catabolic process to glutamate(GO:0010133)
0.1 0.2 GO:0089709 L-histidine transmembrane transport(GO:0089709) L-histidine transport(GO:1902024)
0.1 0.2 GO:0005986 sucrose metabolic process(GO:0005985) sucrose biosynthetic process(GO:0005986) disaccharide biosynthetic process(GO:0046351)
0.1 0.2 GO:0061088 sequestering of zinc ion(GO:0032119) regulation of sequestering of zinc ion(GO:0061088)
0.1 0.2 GO:0015893 folic acid transport(GO:0015884) drug transport(GO:0015893) methotrexate transport(GO:0051958) reduced folate transmembrane transport(GO:0098838)
0.1 0.3 GO:1902514 calcium ion transmembrane transport via high voltage-gated calcium channel(GO:0061577) regulation of calcium ion transmembrane transport via high voltage-gated calcium channel(GO:1902514)
0.1 0.2 GO:0030213 hyaluronan biosynthetic process(GO:0030213)
0.1 0.7 GO:0090303 positive regulation of wound healing(GO:0090303)
0.0 0.8 GO:0046501 protoporphyrinogen IX biosynthetic process(GO:0006782) protoporphyrinogen IX metabolic process(GO:0046501)
0.0 0.3 GO:0090497 mesenchymal cell migration(GO:0090497)
0.0 0.2 GO:0045903 positive regulation of translational fidelity(GO:0045903)
0.0 0.7 GO:0032525 somite rostral/caudal axis specification(GO:0032525)
0.0 0.3 GO:0060394 negative regulation of pathway-restricted SMAD protein phosphorylation(GO:0060394)
0.0 0.2 GO:0035610 protein side chain deglutamylation(GO:0035610)
0.0 0.1 GO:1904088 regulation of convergent extension involved in axis elongation(GO:1901232) positive regulation of epiboly involved in gastrulation with mouth forming second(GO:1904088)
0.0 0.2 GO:0006107 oxaloacetate metabolic process(GO:0006107)
0.0 0.2 GO:0046084 adenine metabolic process(GO:0046083) adenine biosynthetic process(GO:0046084)
0.0 0.1 GO:0010660 negative regulation of muscle cell apoptotic process(GO:0010656) muscle cell apoptotic process(GO:0010657) striated muscle cell apoptotic process(GO:0010658) regulation of muscle cell apoptotic process(GO:0010660) regulation of striated muscle cell apoptotic process(GO:0010662) negative regulation of striated muscle cell apoptotic process(GO:0010664)
0.0 0.5 GO:0036368 cone photoresponse recovery(GO:0036368)
0.0 0.3 GO:0042554 superoxide anion generation(GO:0042554)
0.0 1.0 GO:0000027 ribosomal large subunit assembly(GO:0000027)
0.0 0.5 GO:0042661 regulation of mesodermal cell fate specification(GO:0042661)
0.0 0.1 GO:0010265 SCF complex assembly(GO:0010265)
0.0 0.1 GO:0008344 adult locomotory behavior(GO:0008344)
0.0 0.8 GO:0006995 cellular response to nitrogen starvation(GO:0006995) cellular response to nitrogen levels(GO:0043562)
0.0 0.5 GO:0019747 regulation of isoprenoid metabolic process(GO:0019747) regulation of vitamin metabolic process(GO:0030656) regulation of retinoic acid biosynthetic process(GO:1900052)
0.0 0.2 GO:0045056 transcytosis(GO:0045056)
0.0 0.6 GO:0051481 negative regulation of cytosolic calcium ion concentration(GO:0051481) negative regulation of synaptic transmission, glutamatergic(GO:0051967)
0.0 0.1 GO:0035902 response to immobilization stress(GO:0035902)
0.0 0.6 GO:0097324 melanocyte migration(GO:0097324)
0.0 0.3 GO:0070584 mitochondrion morphogenesis(GO:0070584)
0.0 0.7 GO:0036444 calcium ion transmembrane import into mitochondrion(GO:0036444)
0.0 0.2 GO:0070294 renal sodium ion transport(GO:0003096) renal sodium ion absorption(GO:0070294)
0.0 0.3 GO:1990845 adaptive thermogenesis(GO:1990845)
0.0 0.3 GO:0008210 estrogen metabolic process(GO:0008210)
0.0 0.3 GO:0035479 angioblast cell migration from lateral mesoderm to midline(GO:0035479)
0.0 0.7 GO:0008535 respiratory chain complex IV assembly(GO:0008535)
0.0 0.3 GO:0030240 skeletal muscle thin filament assembly(GO:0030240)
0.0 0.4 GO:0060612 adipose tissue development(GO:0060612)
0.0 0.1 GO:0046391 5-phosphoribose 1-diphosphate biosynthetic process(GO:0006015) 5-phosphoribose 1-diphosphate metabolic process(GO:0046391)
0.0 0.1 GO:0071387 cellular response to cortisol stimulus(GO:0071387)
0.0 0.2 GO:0034454 microtubule anchoring at centrosome(GO:0034454)
0.0 0.4 GO:0051601 exocyst localization(GO:0051601)
0.0 0.1 GO:0031120 snRNA pseudouridine synthesis(GO:0031120)
0.0 0.4 GO:0030878 thyroid gland development(GO:0030878)
0.0 0.2 GO:0097428 protein maturation by iron-sulfur cluster transfer(GO:0097428)
0.0 0.1 GO:0097500 receptor localization to nonmotile primary cilium(GO:0097500) protein localization to ciliary membrane(GO:1903441)
0.0 0.2 GO:0043584 nose development(GO:0043584)
0.0 0.6 GO:0060038 cardiac muscle cell proliferation(GO:0060038)
0.0 0.7 GO:0060034 notochord cell differentiation(GO:0060034)
0.0 0.4 GO:0033198 response to ATP(GO:0033198)
0.0 0.7 GO:0097320 membrane tubulation(GO:0097320)
0.0 0.2 GO:0042362 fat-soluble vitamin biosynthetic process(GO:0042362)
0.0 0.4 GO:0043114 regulation of vascular permeability(GO:0043114)
0.0 0.5 GO:0061300 cerebellum vasculature development(GO:0061300)
0.0 0.3 GO:1904071 presynaptic active zone assembly(GO:1904071)
0.0 0.3 GO:0060118 vestibular receptor cell differentiation(GO:0060114) vestibular receptor cell development(GO:0060118)
0.0 0.7 GO:0015671 oxygen transport(GO:0015671)
0.0 0.1 GO:0038003 opioid receptor signaling pathway(GO:0038003)
0.0 0.5 GO:0033173 calcineurin-NFAT signaling cascade(GO:0033173)
0.0 0.3 GO:0006388 tRNA splicing, via endonucleolytic cleavage and ligation(GO:0006388)
0.0 0.1 GO:0036265 RNA (guanine-N7)-methylation(GO:0036265)
0.0 0.9 GO:0045746 negative regulation of Notch signaling pathway(GO:0045746)
0.0 0.3 GO:0000467 exonucleolytic trimming involved in rRNA processing(GO:0000459) exonucleolytic trimming to generate mature 3'-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000467)
0.0 0.2 GO:0035909 aorta morphogenesis(GO:0035909) dorsal aorta morphogenesis(GO:0035912)
0.0 0.7 GO:0021983 pituitary gland development(GO:0021983)
0.0 0.4 GO:1905150 regulation of voltage-gated sodium channel activity(GO:1905150)
0.0 0.2 GO:0048665 neuron fate specification(GO:0048665)
0.0 0.1 GO:0048785 hatching gland development(GO:0048785)
0.0 0.1 GO:0061188 regulation of chromatin silencing at rDNA(GO:0061187) negative regulation of chromatin silencing at rDNA(GO:0061188)
0.0 1.6 GO:0021515 cell differentiation in spinal cord(GO:0021515)
0.0 0.3 GO:0006054 N-acetylneuraminate metabolic process(GO:0006054)
0.0 0.2 GO:0006682 galactosylceramide biosynthetic process(GO:0006682) galactolipid biosynthetic process(GO:0019375)
0.0 0.1 GO:0021877 forebrain neuron fate commitment(GO:0021877)
0.0 0.2 GO:0043092 amino acid import(GO:0043090) L-amino acid import(GO:0043092)
0.0 0.1 GO:0014707 branchiomeric skeletal muscle development(GO:0014707)
0.0 0.1 GO:0009312 oligosaccharide biosynthetic process(GO:0009312)
0.0 0.2 GO:0046959 nonassociative learning(GO:0046958) habituation(GO:0046959)
0.0 0.4 GO:0031033 myosin filament organization(GO:0031033)
0.0 0.2 GO:0072488 ammonium transmembrane transport(GO:0072488)
0.0 0.4 GO:0001952 regulation of cell-matrix adhesion(GO:0001952)
0.0 0.1 GO:0089700 endocardial cushion morphogenesis(GO:0003203) endocardial cushion formation(GO:0003272) protein kinase D signaling(GO:0089700)
0.0 0.2 GO:0007288 sperm axoneme assembly(GO:0007288)
0.0 0.1 GO:0006545 glycine biosynthetic process(GO:0006545)
0.0 0.2 GO:0046341 CDP-diacylglycerol biosynthetic process(GO:0016024) CDP-diacylglycerol metabolic process(GO:0046341)
0.0 0.4 GO:0070527 platelet aggregation(GO:0070527)
0.0 0.1 GO:0036306 embryonic heart tube elongation(GO:0036306)
0.0 0.2 GO:0006044 N-acetylglucosamine metabolic process(GO:0006044)
0.0 2.4 GO:0050768 negative regulation of neurogenesis(GO:0050768)
0.0 0.7 GO:0015804 neutral amino acid transport(GO:0015804)
0.0 0.1 GO:0044341 sodium-dependent phosphate transport(GO:0044341)
0.0 0.7 GO:0061386 closure of optic fissure(GO:0061386)
0.0 0.1 GO:1904158 axonemal central apparatus assembly(GO:1904158)
0.0 0.3 GO:0000463 maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000463)
0.0 0.4 GO:0048512 rhythmic behavior(GO:0007622) circadian behavior(GO:0048512)
0.0 1.0 GO:0060028 convergent extension involved in axis elongation(GO:0060028)
0.0 0.1 GO:0070208 protein heterotrimerization(GO:0070208)
0.0 0.1 GO:0019184 nonribosomal peptide biosynthetic process(GO:0019184)
0.0 0.1 GO:0015074 DNA integration(GO:0015074)
0.0 0.4 GO:0042159 lipoprotein catabolic process(GO:0042159)
0.0 0.4 GO:0006120 mitochondrial electron transport, NADH to ubiquinone(GO:0006120)
0.0 0.3 GO:0036353 histone H2A-K119 monoubiquitination(GO:0036353)
0.0 0.1 GO:2001240 histone dephosphorylation(GO:0016576) negative regulation of signal transduction in absence of ligand(GO:1901099) regulation of extrinsic apoptotic signaling pathway in absence of ligand(GO:2001239) negative regulation of extrinsic apoptotic signaling pathway in absence of ligand(GO:2001240)
0.0 0.2 GO:0006543 glutamate biosynthetic process(GO:0006537) glutamine catabolic process(GO:0006543)
0.0 0.2 GO:1902262 apoptotic process involved in patterning of blood vessels(GO:1902262)
0.0 0.6 GO:0045839 negative regulation of mitotic nuclear division(GO:0045839)
0.0 0.2 GO:0046520 sphingoid biosynthetic process(GO:0046520)
0.0 0.4 GO:0030032 lamellipodium assembly(GO:0030032)
0.0 0.9 GO:0036269 swimming behavior(GO:0036269)
0.0 0.2 GO:0034497 protein localization to pre-autophagosomal structure(GO:0034497)
0.0 0.1 GO:0033628 regulation of cell adhesion mediated by integrin(GO:0033628)
0.0 0.3 GO:0002761 regulation of myeloid leukocyte differentiation(GO:0002761)
0.0 0.3 GO:0046113 pyrimidine nucleobase catabolic process(GO:0006208) nucleobase catabolic process(GO:0046113)
0.0 0.1 GO:0090136 epithelial cell-cell adhesion(GO:0090136)
0.0 0.3 GO:2000601 positive regulation of actin nucleation(GO:0051127) positive regulation of Arp2/3 complex-mediated actin nucleation(GO:2000601)
0.0 0.3 GO:0060997 dendritic spine morphogenesis(GO:0060997)
0.0 0.2 GO:0030225 macrophage differentiation(GO:0030225)
0.0 0.6 GO:0007586 digestion(GO:0007586)
0.0 0.4 GO:0035622 intrahepatic bile duct development(GO:0035622)
0.0 0.1 GO:0060837 blood vessel endothelial cell differentiation(GO:0060837)
0.0 0.2 GO:0000470 maturation of LSU-rRNA(GO:0000470)
0.0 0.5 GO:0035118 embryonic pectoral fin morphogenesis(GO:0035118)
0.0 0.4 GO:0035435 phosphate ion transmembrane transport(GO:0035435)
0.0 0.0 GO:0000472 endonucleolytic cleavage to generate mature 5'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000472) endonucleolytic cleavage in 5'-ETS of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000480) rRNA 5'-end processing(GO:0000967) ncRNA 5'-end processing(GO:0034471)
0.0 0.3 GO:0097178 ruffle organization(GO:0031529) ruffle assembly(GO:0097178)
0.0 0.3 GO:2001235 positive regulation of apoptotic signaling pathway(GO:2001235)
0.0 0.3 GO:1901222 regulation of NIK/NF-kappaB signaling(GO:1901222)
0.0 0.2 GO:0051968 positive regulation of synaptic transmission, glutamatergic(GO:0051968)
0.0 0.3 GO:0010811 positive regulation of cell-substrate adhesion(GO:0010811)
0.0 0.1 GO:0030511 positive regulation of transforming growth factor beta receptor signaling pathway(GO:0030511) positive regulation of cellular response to transforming growth factor beta stimulus(GO:1903846)
0.0 0.1 GO:0042059 negative regulation of epidermal growth factor receptor signaling pathway(GO:0042059) negative regulation of ERBB signaling pathway(GO:1901185)
0.0 0.8 GO:0042738 drug metabolic process(GO:0017144) drug catabolic process(GO:0042737) exogenous drug catabolic process(GO:0042738)
0.0 0.1 GO:0051694 pointed-end actin filament capping(GO:0051694)
0.0 0.2 GO:0070979 protein K11-linked ubiquitination(GO:0070979)
0.0 0.2 GO:0050795 regulation of behavior(GO:0050795)
0.0 0.7 GO:0071466 cellular response to xenobiotic stimulus(GO:0071466)
0.0 0.5 GO:0006376 mRNA splice site selection(GO:0006376)
0.0 1.1 GO:0007229 integrin-mediated signaling pathway(GO:0007229)
0.0 0.4 GO:0014003 oligodendrocyte development(GO:0014003)
0.0 0.2 GO:0046085 adenosine metabolic process(GO:0046085)
0.0 0.2 GO:0032088 negative regulation of NF-kappaB transcription factor activity(GO:0032088)
0.0 0.1 GO:0098795 mRNA cleavage involved in gene silencing by miRNA(GO:0035279) mRNA cleavage involved in gene silencing(GO:0098795)
0.0 0.8 GO:0019722 calcium-mediated signaling(GO:0019722)
0.0 0.1 GO:0030206 chondroitin sulfate biosynthetic process(GO:0030206)
0.0 0.2 GO:0061726 mitophagy(GO:0000422) mitochondrion disassembly(GO:0061726)
0.0 0.1 GO:0036268 swimming(GO:0036268)
0.0 0.3 GO:0015986 energy coupled proton transport, down electrochemical gradient(GO:0015985) ATP synthesis coupled proton transport(GO:0015986)
0.0 0.2 GO:0015858 nucleoside transport(GO:0015858) nucleoside transmembrane transport(GO:1901642)
0.0 0.5 GO:0048384 retinoic acid receptor signaling pathway(GO:0048384)
0.0 0.1 GO:0001881 receptor recycling(GO:0001881)
0.0 0.1 GO:0060541 respiratory system development(GO:0060541)
0.0 0.2 GO:0002430 complement receptor mediated signaling pathway(GO:0002430)
0.0 0.1 GO:1902946 protein localization to endosome(GO:0036010) positive regulation of receptor-mediated endocytosis(GO:0048260) protein localization to early endosome(GO:1902946)
0.0 0.1 GO:0048312 intracellular distribution of mitochondria(GO:0048312)
0.0 0.3 GO:0072348 sulfur compound transport(GO:0072348)
0.0 0.1 GO:0046294 formaldehyde metabolic process(GO:0046292) formaldehyde catabolic process(GO:0046294)
0.0 0.1 GO:0007172 signal complex assembly(GO:0007172)
0.0 0.1 GO:0043328 protein targeting to vacuole involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway(GO:0043328)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.6 GO:0034363 intermediate-density lipoprotein particle(GO:0034363)
0.1 0.8 GO:0016012 sarcoglycan complex(GO:0016012)
0.1 1.3 GO:0034364 high-density lipoprotein particle(GO:0034364)
0.1 0.4 GO:0097134 cyclin E1-CDK2 complex(GO:0097134)
0.1 0.7 GO:0033018 sarcoplasmic reticulum lumen(GO:0033018)
0.1 0.3 GO:0030062 mitochondrial alpha-ketoglutarate dehydrogenase complex(GO:0005947) mitochondrial tricarboxylic acid cycle enzyme complex(GO:0030062)
0.1 0.5 GO:0005955 calcineurin complex(GO:0005955)
0.1 0.5 GO:0000015 phosphopyruvate hydratase complex(GO:0000015)
0.1 3.8 GO:0022625 cytosolic large ribosomal subunit(GO:0022625)
0.1 0.2 GO:1990072 TRAPPIII protein complex(GO:1990072)
0.1 0.7 GO:0031838 haptoglobin-hemoglobin complex(GO:0031838)
0.1 0.2 GO:0016600 flotillin complex(GO:0016600)
0.1 2.4 GO:0005861 troponin complex(GO:0005861)
0.1 0.7 GO:1990246 uniplex complex(GO:1990246)
0.0 0.5 GO:0005892 acetylcholine-gated channel complex(GO:0005892)
0.0 0.7 GO:0030315 T-tubule(GO:0030315)
0.0 0.3 GO:0043020 NADPH oxidase complex(GO:0043020)
0.0 0.2 GO:0005850 eukaryotic translation initiation factor 2 complex(GO:0005850)
0.0 0.1 GO:0002189 ribose phosphate diphosphokinase complex(GO:0002189)
0.0 0.5 GO:0002102 podosome(GO:0002102)
0.0 0.3 GO:0098982 GABA-ergic synapse(GO:0098982)
0.0 0.1 GO:0008537 proteasome activator complex(GO:0008537)
0.0 0.2 GO:0034045 pre-autophagosomal structure membrane(GO:0034045)
0.0 0.1 GO:0072588 box H/ACA snoRNP complex(GO:0031429) box H/ACA RNP complex(GO:0072588)
0.0 0.3 GO:0008250 oligosaccharyltransferase complex(GO:0008250)
0.0 0.9 GO:0031105 septin ring(GO:0005940) septin complex(GO:0031105) septin cytoskeleton(GO:0032156)
0.0 0.4 GO:0032591 dendritic spine membrane(GO:0032591)
0.0 0.2 GO:0071914 prominosome(GO:0071914)
0.0 0.2 GO:0019773 proteasome core complex, alpha-subunit complex(GO:0019773)
0.0 0.2 GO:0030122 AP-2 adaptor complex(GO:0030122)
0.0 0.4 GO:0044453 integral component of nuclear inner membrane(GO:0005639) intrinsic component of nuclear inner membrane(GO:0031229) nuclear membrane part(GO:0044453)
0.0 0.5 GO:0030687 preribosome, large subunit precursor(GO:0030687)
0.0 1.4 GO:0005581 collagen trimer(GO:0005581)
0.0 0.3 GO:0000276 mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)(GO:0000276)
0.0 0.4 GO:0043195 terminal bouton(GO:0043195)
0.0 0.7 GO:0042470 melanosome(GO:0042470) pigment granule(GO:0048770)
0.0 0.1 GO:0031262 Ndc80 complex(GO:0031262)
0.0 0.3 GO:0048787 presynaptic active zone membrane(GO:0048787)
0.0 1.6 GO:0005604 basement membrane(GO:0005604)
0.0 0.8 GO:0022626 cytosolic ribosome(GO:0022626) cytosolic small ribosomal subunit(GO:0022627)
0.0 0.3 GO:0031209 SCAR complex(GO:0031209)
0.0 0.5 GO:0098978 glutamatergic synapse(GO:0098978)
0.0 0.3 GO:0071144 SMAD2-SMAD3 protein complex(GO:0071144)
0.0 0.2 GO:0034451 centriolar satellite(GO:0034451)
0.0 0.8 GO:0031305 integral component of mitochondrial inner membrane(GO:0031305)
0.0 0.2 GO:0005832 chaperonin-containing T-complex(GO:0005832)
0.0 0.2 GO:0005665 DNA-directed RNA polymerase II, core complex(GO:0005665)
0.0 0.5 GO:0032281 AMPA glutamate receptor complex(GO:0032281)
0.0 0.2 GO:0098827 endoplasmic reticulum tubular network(GO:0071782) endoplasmic reticulum subcompartment(GO:0098827)
0.0 0.9 GO:0030672 synaptic vesicle membrane(GO:0030672) exocytic vesicle membrane(GO:0099501)
0.0 0.6 GO:0030964 mitochondrial respiratory chain complex I(GO:0005747) NADH dehydrogenase complex(GO:0030964) respiratory chain complex I(GO:0045271)
0.0 0.7 GO:0097517 stress fiber(GO:0001725) contractile actin filament bundle(GO:0097517)
0.0 0.7 GO:0016342 catenin complex(GO:0016342)
0.0 0.3 GO:0046658 anchored component of plasma membrane(GO:0046658)
0.0 0.3 GO:0035102 PRC1 complex(GO:0035102)
0.0 1.4 GO:0016324 apical plasma membrane(GO:0016324)
0.0 0.1 GO:0032432 actin filament bundle(GO:0032432)
0.0 0.2 GO:0031680 G-protein beta/gamma-subunit complex(GO:0031680)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 0.8 GO:0016748 succinyltransferase activity(GO:0016748)
0.2 0.6 GO:0043395 heparan sulfate proteoglycan binding(GO:0043395)
0.2 0.6 GO:0070815 peptidyl-lysine 5-dioxygenase activity(GO:0070815)
0.2 0.5 GO:0048030 disaccharide binding(GO:0048030)
0.2 0.8 GO:0060228 phosphatidylcholine-sterol O-acyltransferase activator activity(GO:0060228)
0.2 2.3 GO:0005504 fatty acid binding(GO:0005504)
0.1 0.9 GO:0004743 pyruvate kinase activity(GO:0004743)
0.1 0.4 GO:1990430 extracellular matrix protein binding(GO:1990430)
0.1 0.5 GO:0004772 sterol O-acyltransferase activity(GO:0004772) cholesterol O-acyltransferase activity(GO:0034736)
0.1 0.8 GO:0008158 hedgehog receptor activity(GO:0008158)
0.1 0.9 GO:0001217 bacterial-type RNA polymerase transcription factor activity, sequence-specific DNA binding(GO:0001130) bacterial-type RNA polymerase transcriptional repressor activity, sequence-specific DNA binding(GO:0001217)
0.1 0.6 GO:0004645 phosphorylase activity(GO:0004645) glycogen phosphorylase activity(GO:0008184)
0.1 0.6 GO:0005542 folic acid binding(GO:0005542)
0.1 0.3 GO:0070051 fibrinogen binding(GO:0070051)
0.1 0.5 GO:0008097 5S rRNA binding(GO:0008097)
0.1 0.4 GO:0004945 angiotensin type II receptor activity(GO:0004945)
0.1 0.5 GO:0047757 chondroitin-glucuronate 5-epimerase activity(GO:0047757)
0.1 0.4 GO:0003884 D-amino-acid oxidase activity(GO:0003884)
0.1 0.3 GO:0017077 oxidative phosphorylation uncoupler activity(GO:0017077)
0.1 0.5 GO:0033192 calcium-dependent protein serine/threonine phosphatase activity(GO:0004723) calmodulin-dependent protein phosphatase activity(GO:0033192)
0.1 0.3 GO:0052654 branched-chain-amino-acid transaminase activity(GO:0004084) L-leucine transaminase activity(GO:0052654) L-valine transaminase activity(GO:0052655) L-isoleucine transaminase activity(GO:0052656)
0.1 0.5 GO:0070888 E-box binding(GO:0070888)
0.1 0.4 GO:0070180 large ribosomal subunit rRNA binding(GO:0070180)
0.1 0.7 GO:0016936 galactoside binding(GO:0016936)
0.1 0.3 GO:0004657 proline dehydrogenase activity(GO:0004657)
0.1 0.3 GO:0070052 collagen V binding(GO:0070052)
0.1 0.5 GO:0004861 cyclin-dependent protein serine/threonine kinase inhibitor activity(GO:0004861)
0.1 0.4 GO:0016316 phosphatidylinositol-3,4-bisphosphate 4-phosphatase activity(GO:0016316)
0.1 0.5 GO:0004634 phosphopyruvate hydratase activity(GO:0004634)
0.1 0.7 GO:0031720 haptoglobin binding(GO:0031720)
0.1 0.2 GO:0042132 fructose 1,6-bisphosphate 1-phosphatase activity(GO:0042132)
0.1 0.2 GO:0001223 transcription coactivator binding(GO:0001223)
0.0 0.2 GO:0043295 glutathione binding(GO:0043295)
0.0 0.2 GO:0031843 neuropeptide Y receptor binding(GO:0031841) type 2 neuropeptide Y receptor binding(GO:0031843)
0.0 0.2 GO:0030060 L-malate dehydrogenase activity(GO:0030060)
0.0 0.1 GO:0038046 enkephalin receptor activity(GO:0038046)
0.0 0.4 GO:0004062 aryl sulfotransferase activity(GO:0004062)
0.0 0.6 GO:0001591 dopamine neurotransmitter receptor activity, coupled via Gi/Go(GO:0001591)
0.0 0.2 GO:0043023 ribosomal large subunit binding(GO:0043023)
0.0 0.2 GO:0051059 NF-kappaB binding(GO:0051059)
0.0 1.1 GO:0048306 calcium-dependent protein binding(GO:0048306)
0.0 0.3 GO:0004517 nitric-oxide synthase activity(GO:0004517)
0.0 0.3 GO:0016175 superoxide-generating NADPH oxidase activity(GO:0016175)
0.0 0.2 GO:0017040 ceramidase activity(GO:0017040)
0.0 0.2 GO:0016521 pituitary adenylate cyclase activating polypeptide activity(GO:0016521)
0.0 0.1 GO:0004749 ribose phosphate diphosphokinase activity(GO:0004749)
0.0 0.2 GO:0042169 SH2 domain binding(GO:0042169)
0.0 0.2 GO:0005412 glucose:sodium symporter activity(GO:0005412)
0.0 0.3 GO:0008048 calcium sensitive guanylate cyclase activator activity(GO:0008048)
0.0 0.4 GO:0035381 extracellular ATP-gated cation channel activity(GO:0004931) ATP-gated ion channel activity(GO:0035381)
0.0 1.1 GO:0005184 neuropeptide hormone activity(GO:0005184)
0.0 0.2 GO:0004459 L-lactate dehydrogenase activity(GO:0004459)
0.0 0.1 GO:0046556 alpha-L-arabinofuranosidase activity(GO:0046556)
0.0 0.1 GO:0031716 calcitonin receptor binding(GO:0031716)
0.0 0.4 GO:0005007 fibroblast growth factor-activated receptor activity(GO:0005007)
0.0 0.3 GO:0071933 Arp2/3 complex binding(GO:0071933)
0.0 0.2 GO:1990380 Lys48-specific deubiquitinase activity(GO:1990380)
0.0 0.1 GO:0033842 N-acetyl-beta-glucosaminyl-glycoprotein 4-beta-N-acetylgalactosaminyltransferase activity(GO:0033842)
0.0 0.2 GO:0001517 N-acetylglucosamine 6-O-sulfotransferase activity(GO:0001517)
0.0 0.3 GO:0004157 dihydropyrimidinase activity(GO:0004157)
0.0 5.0 GO:0003735 structural constituent of ribosome(GO:0003735)
0.0 0.7 GO:0017110 nucleoside-diphosphatase activity(GO:0017110)
0.0 0.4 GO:0005315 inorganic phosphate transmembrane transporter activity(GO:0005315)
0.0 0.4 GO:0015187 glycine transmembrane transporter activity(GO:0015187)
0.0 0.1 GO:0016531 copper chaperone activity(GO:0016531)
0.0 0.3 GO:0043325 phosphatidylinositol-3,4-bisphosphate binding(GO:0043325)
0.0 0.3 GO:0003841 1-acylglycerol-3-phosphate O-acyltransferase activity(GO:0003841)
0.0 0.3 GO:0005021 vascular endothelial growth factor-activated receptor activity(GO:0005021)
0.0 0.2 GO:0016742 hydroxymethyl-, formyl- and related transferase activity(GO:0016742)
0.0 0.7 GO:0015175 neutral amino acid transmembrane transporter activity(GO:0015175)
0.0 0.2 GO:0043035 chromatin insulator sequence binding(GO:0043035)
0.0 0.1 GO:0061656 SUMO conjugating enzyme activity(GO:0061656)
0.0 0.1 GO:0070735 protein-glycine ligase activity(GO:0070735) tubulin-glycine ligase activity(GO:0070738)
0.0 0.4 GO:0042813 Wnt-activated receptor activity(GO:0042813)
0.0 0.1 GO:0005093 Rab GDP-dissociation inhibitor activity(GO:0005093)
0.0 0.1 GO:0005436 sodium:phosphate symporter activity(GO:0005436)
0.0 0.2 GO:0001733 galactosylceramide sulfotransferase activity(GO:0001733) galactose 3-O-sulfotransferase activity(GO:0050694)
0.0 0.5 GO:0022848 acetylcholine-gated cation channel activity(GO:0022848)
0.0 0.1 GO:0061133 endopeptidase activator activity(GO:0061133)
0.0 0.4 GO:0005005 transmembrane-ephrin receptor activity(GO:0005005)
0.0 0.2 GO:0008504 monoamine transmembrane transporter activity(GO:0008504)
0.0 0.1 GO:0032574 5'-3' RNA helicase activity(GO:0032574)
0.0 0.3 GO:0008327 methyl-CpG binding(GO:0008327)
0.0 0.1 GO:0072545 tyrosine binding(GO:0072545)
0.0 0.1 GO:0004999 vasoactive intestinal polypeptide receptor activity(GO:0004999)
0.0 0.3 GO:0098882 structural constituent of presynaptic active zone(GO:0098882)
0.0 0.1 GO:0048487 beta-tubulin binding(GO:0048487)
0.0 0.7 GO:0004864 protein phosphatase inhibitor activity(GO:0004864)
0.0 0.2 GO:0080025 phosphatidylinositol-3,5-bisphosphate binding(GO:0080025)
0.0 0.9 GO:0042826 histone deacetylase binding(GO:0042826)
0.0 0.2 GO:0004971 AMPA glutamate receptor activity(GO:0004971)
0.0 0.0 GO:0019777 Atg12 transferase activity(GO:0019777)
0.0 0.1 GO:0004303 estradiol 17-beta-dehydrogenase activity(GO:0004303)
0.0 0.3 GO:0070411 I-SMAD binding(GO:0070411)
0.0 0.4 GO:0017080 sodium channel regulator activity(GO:0017080)
0.0 1.0 GO:0030215 semaphorin receptor binding(GO:0030215)
0.0 0.4 GO:0005112 Notch binding(GO:0005112)
0.0 0.1 GO:0047238 glucuronosyl-N-acetylgalactosaminyl-proteoglycan 4-beta-N-acetylgalactosaminyltransferase activity(GO:0047238)
0.0 0.3 GO:0070001 aspartic-type endopeptidase activity(GO:0004190) aspartic-type peptidase activity(GO:0070001)
0.0 0.2 GO:0019911 structural constituent of myelin sheath(GO:0019911)
0.0 0.2 GO:0098748 clathrin adaptor activity(GO:0035615) endocytic adaptor activity(GO:0098748)
0.0 0.1 GO:0046934 phosphatidylinositol-4,5-bisphosphate 3-kinase activity(GO:0046934) phosphatidylinositol-3,4-bisphosphate 5-kinase activity(GO:0052812)
0.0 0.3 GO:0031492 nucleosomal DNA binding(GO:0031492)
0.0 0.1 GO:0005153 interleukin-8 receptor binding(GO:0005153)
0.0 0.7 GO:0003755 peptidyl-prolyl cis-trans isomerase activity(GO:0003755)
0.0 0.1 GO:0004740 pyruvate dehydrogenase (acetyl-transferring) kinase activity(GO:0004740)
0.0 0.1 GO:0000774 adenyl-nucleotide exchange factor activity(GO:0000774)
0.0 0.1 GO:0047676 arachidonate-CoA ligase activity(GO:0047676)
0.0 0.1 GO:0050431 transforming growth factor beta binding(GO:0050431)
0.0 0.2 GO:0015272 ATP-activated inward rectifier potassium channel activity(GO:0015272)
0.0 0.1 GO:0060182 apelin receptor activity(GO:0060182)
0.0 1.2 GO:0045296 cadherin binding(GO:0045296)
0.0 0.2 GO:0005080 protein kinase C binding(GO:0005080)
0.0 0.2 GO:0019870 chloride channel inhibitor activity(GO:0019869) potassium channel inhibitor activity(GO:0019870)
0.0 0.1 GO:0044323 retinoic acid-responsive element binding(GO:0044323)
0.0 0.6 GO:0004683 calmodulin-dependent protein kinase activity(GO:0004683)
0.0 0.0 GO:0034511 U3 snoRNA binding(GO:0034511)
0.0 0.6 GO:0003950 NAD+ ADP-ribosyltransferase activity(GO:0003950)
0.0 0.8 GO:0016712 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen(GO:0016712)
0.0 0.3 GO:0004806 triglyceride lipase activity(GO:0004806)
0.0 0.1 GO:0043531 ADP binding(GO:0043531)
0.0 0.1 GO:0070567 cytidylyltransferase activity(GO:0070567)
0.0 0.1 GO:0015168 glycerol transmembrane transporter activity(GO:0015168)
0.0 0.1 GO:0072542 phosphatase activator activity(GO:0019211) protein phosphatase activator activity(GO:0072542)
0.0 0.2 GO:0008519 ammonium transmembrane transporter activity(GO:0008519)
0.0 0.1 GO:0003886 DNA (cytosine-5-)-methyltransferase activity(GO:0003886)
0.0 0.2 GO:0035497 cAMP response element binding(GO:0035497)
0.0 0.3 GO:0004089 carbonate dehydratase activity(GO:0004089)
0.0 0.1 GO:0015174 basic amino acid transmembrane transporter activity(GO:0015174)
0.0 0.2 GO:0004875 complement receptor activity(GO:0004875)
0.0 0.2 GO:0008301 DNA binding, bending(GO:0008301)
0.0 0.1 GO:0045236 CXCR chemokine receptor binding(GO:0045236)
0.0 0.1 GO:0019136 deoxynucleoside kinase activity(GO:0019136)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.2 PID P38 GAMMA DELTA PATHWAY Signaling mediated by p38-gamma and p38-delta
0.0 0.5 ST G ALPHA S PATHWAY G alpha s Pathway
0.0 0.2 ST JAK STAT PATHWAY Jak-STAT Pathway
0.0 0.5 PID CONE PATHWAY Visual signal transduction: Cones
0.0 0.8 PID HDAC CLASSIII PATHWAY Signaling events mediated by HDAC Class III
0.0 0.4 PID HEDGEHOG 2PATHWAY Signaling events mediated by the Hedgehog family
0.0 0.3 PID TCR CALCIUM PATHWAY Calcium signaling in the CD4+ TCR pathway
0.0 0.4 PID INTEGRIN A4B1 PATHWAY Alpha4 beta1 integrin signaling events
0.0 0.4 PID ERBB1 RECEPTOR PROXIMAL PATHWAY EGF receptor (ErbB1) signaling pathway
0.0 0.5 SIG REGULATION OF THE ACTIN CYTOSKELETON BY RHO GTPASES Genes related to regulation of the actin cytoskeleton
0.0 0.4 PID WNT SIGNALING PATHWAY Wnt signaling network
0.0 0.5 PID AJDISS 2PATHWAY Posttranslational regulation of adherens junction stability and dissassembly
0.0 0.1 PID NFKAPPAB ATYPICAL PATHWAY Atypical NF-kappaB pathway
0.0 0.5 PID SYNDECAN 1 PATHWAY Syndecan-1-mediated signaling events
0.0 0.4 PID FGF PATHWAY FGF signaling pathway
0.0 0.4 PID IL2 PI3K PATHWAY IL2 signaling events mediated by PI3K
0.0 0.4 NABA PROTEOGLYCANS Genes encoding proteoglycans

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.5 REACTOME REGULATION OF COMPLEMENT CASCADE Genes involved in Regulation of Complement cascade
0.1 1.2 REACTOME KERATAN SULFATE DEGRADATION Genes involved in Keratan sulfate degradation
0.1 1.0 REACTOME MTORC1 MEDIATED SIGNALLING Genes involved in mTORC1-mediated signalling
0.1 0.5 REACTOME FGFR4 LIGAND BINDING AND ACTIVATION Genes involved in FGFR4 ligand binding and activation
0.1 0.3 REACTOME PURINE CATABOLISM Genes involved in Purine catabolism
0.1 0.5 REACTOME HORMONE SENSITIVE LIPASE HSL MEDIATED TRIACYLGLYCEROL HYDROLYSIS Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis
0.1 0.5 REACTOME CHYLOMICRON MEDIATED LIPID TRANSPORT Genes involved in Chylomicron-mediated lipid transport
0.0 0.4 REACTOME PRESYNAPTIC NICOTINIC ACETYLCHOLINE RECEPTORS Genes involved in Presynaptic nicotinic acetylcholine receptors
0.0 0.4 REACTOME DCC MEDIATED ATTRACTIVE SIGNALING Genes involved in DCC mediated attractive signaling
0.0 0.2 REACTOME OLFACTORY SIGNALING PATHWAY Genes involved in Olfactory Signaling Pathway
0.0 0.8 REACTOME REGULATION OF GENE EXPRESSION IN BETA CELLS Genes involved in Regulation of gene expression in beta cells
0.0 4.6 REACTOME PEPTIDE CHAIN ELONGATION Genes involved in Peptide chain elongation
0.0 0.3 REACTOME PHOSPHORYLATION OF CD3 AND TCR ZETA CHAINS Genes involved in Phosphorylation of CD3 and TCR zeta chains
0.0 0.5 REACTOME P130CAS LINKAGE TO MAPK SIGNALING FOR INTEGRINS Genes involved in p130Cas linkage to MAPK signaling for integrins
0.0 0.1 REACTOME CTLA4 INHIBITORY SIGNALING Genes involved in CTLA4 inhibitory signaling
0.0 0.2 REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES Genes involved in Chemokine receptors bind chemokines
0.0 0.4 REACTOME METABOLISM OF PORPHYRINS Genes involved in Metabolism of porphyrins
0.0 1.7 REACTOME RESPIRATORY ELECTRON TRANSPORT ATP SYNTHESIS BY CHEMIOSMOTIC COUPLING AND HEAT PRODUCTION BY UNCOUPLING PROTEINS Genes involved in Respiratory electron transport, ATP synthesis by chemiosmotic coupling, and heat production by uncoupling proteins.
0.0 0.2 REACTOME SEROTONIN RECEPTORS Genes involved in Serotonin receptors
0.0 0.5 REACTOME DARPP 32 EVENTS Genes involved in DARPP-32 events
0.0 0.9 REACTOME MYOGENESIS Genes involved in Myogenesis
0.0 0.6 REACTOME AMINO ACID TRANSPORT ACROSS THE PLASMA MEMBRANE Genes involved in Amino acid transport across the plasma membrane
0.0 0.8 REACTOME FORMATION OF TRANSCRIPTION COUPLED NER TC NER REPAIR COMPLEX Genes involved in Formation of transcription-coupled NER (TC-NER) repair complex
0.0 0.2 REACTOME RETROGRADE NEUROTROPHIN SIGNALLING Genes involved in Retrograde neurotrophin signalling
0.0 0.6 REACTOME STEROID HORMONES Genes involved in Steroid hormones
0.0 0.2 REACTOME THE ACTIVATION OF ARYLSULFATASES Genes involved in The activation of arylsulfatases
0.0 0.5 REACTOME PRE NOTCH TRANSCRIPTION AND TRANSLATION Genes involved in Pre-NOTCH Transcription and Translation
0.0 0.4 REACTOME BRANCHED CHAIN AMINO ACID CATABOLISM Genes involved in Branched-chain amino acid catabolism
0.0 0.9 REACTOME COLLAGEN FORMATION Genes involved in Collagen formation
0.0 0.3 REACTOME SYNTHESIS OF PIPS AT THE EARLY ENDOSOME MEMBRANE Genes involved in Synthesis of PIPs at the early endosome membrane
0.0 0.2 REACTOME SEMA3A PAK DEPENDENT AXON REPULSION Genes involved in Sema3A PAK dependent Axon repulsion
0.0 0.2 REACTOME FORMATION OF THE TERNARY COMPLEX AND SUBSEQUENTLY THE 43S COMPLEX Genes involved in Formation of the ternary complex, and subsequently, the 43S complex
0.0 0.2 REACTOME PURINE RIBONUCLEOSIDE MONOPHOSPHATE BIOSYNTHESIS Genes involved in Purine ribonucleoside monophosphate biosynthesis
0.0 0.2 REACTOME HYALURONAN METABOLISM Genes involved in Hyaluronan metabolism
0.0 0.3 REACTOME LATENT INFECTION OF HOMO SAPIENS WITH MYCOBACTERIUM TUBERCULOSIS Genes involved in Latent infection of Homo sapiens with Mycobacterium tuberculosis
0.0 0.1 REACTOME HORMONE LIGAND BINDING RECEPTORS Genes involved in Hormone ligand-binding receptors
0.0 0.1 REACTOME NA CL DEPENDENT NEUROTRANSMITTER TRANSPORTERS Genes involved in Na+/Cl- dependent neurotransmitter transporters
0.0 0.9 REACTOME PEPTIDE LIGAND BINDING RECEPTORS Genes involved in Peptide ligand-binding receptors
0.0 0.4 REACTOME CROSS PRESENTATION OF SOLUBLE EXOGENOUS ANTIGENS ENDOSOMES Genes involved in Cross-presentation of soluble exogenous antigens (endosomes)
0.0 0.6 REACTOME CLASS B 2 SECRETIN FAMILY RECEPTORS Genes involved in Class B/2 (Secretin family receptors)
0.0 0.1 REACTOME MEMBRANE BINDING AND TARGETTING OF GAG PROTEINS Genes involved in Membrane binding and targetting of GAG proteins
0.0 0.3 REACTOME TIE2 SIGNALING Genes involved in Tie2 Signaling