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PRJNA195909:zebrafish embryo and larva development

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Results for meox2a

Z-value: 0.73

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Transcription factors associated with meox2a

Gene Symbol Gene ID Gene Info
ENSDARG00000040911 mesenchyme homeobox 2a

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
meox2adr11_v1_chr15_-_34458495_344584950.655.6e-02Click!

Activity profile of meox2a motif

Sorted Z-values of meox2a motif

Promoter Log-likelihood Transcript Gene Gene Info
chr4_+_9669717 1.36 ENSDART00000004604
si:dkey-153k10.9
chr6_+_55032439 1.07 ENSDART00000164232
ENSDART00000158845
ENSDART00000157584
ENSDART00000026359
ENSDART00000122794
ENSDART00000183742
myosin binding protein Hb
chr22_-_10459880 1.04 ENSDART00000064801
osteoglycin
chr21_+_26390549 1.00 ENSDART00000185643
thymosin, beta
chr19_-_42607451 0.96 ENSDART00000004392
FK506 binding protein 9
chr19_+_12915498 0.95 ENSDART00000132892
collagen triple helix repeat containing 1a
chr12_-_26407092 0.95 ENSDART00000178687
myozenin 1b
chr25_+_20089986 0.88 ENSDART00000143441
ENSDART00000184073
troponin I4b, tandem duplicate 2
chr23_-_23401305 0.76 ENSDART00000078936
hairy-related 9
chr1_-_12278056 0.74 ENSDART00000139336
ENSDART00000137463
complexin 2, like
chr1_+_17593392 0.74 ENSDART00000078889
helt bHLH transcription factor
chr6_-_58764672 0.73 ENSDART00000154322
sterol O-acyltransferase 2
chr19_-_32150078 0.73 ENSDART00000134934
ENSDART00000186410
ENSDART00000181780
phosphoprotein membrane anchor with glycosphingolipid microdomains 1
chr25_+_20091021 0.72 ENSDART00000187545
ENSDART00000053265
troponin I4b, tandem duplicate 2
chr9_-_22310919 0.68 ENSDART00000108719
crystallin, gamma M2d10
chr9_-_22245572 0.68 ENSDART00000114943
crystallin, gamma M2d4
chr17_+_17955063 0.65 ENSDART00000104999
coiled-coil domain containing 85C, a
chr12_+_13118540 0.65 ENSDART00000077840
ENSDART00000127870
calymmin
chr3_+_28953274 0.63 ENSDART00000133528
ENSDART00000103602
lectin, galactoside-binding, soluble, 2a
chr21_-_43015383 0.63 ENSDART00000065097
dihydropyrimidinase-like 3
chr21_+_28958471 0.61 ENSDART00000144331
ENSDART00000005929
protein phosphatase 3, catalytic subunit, alpha isozyme
chr5_+_32222303 0.59 ENSDART00000051362
myosin heavy chain 4
chr13_+_43247936 0.59 ENSDART00000126850
ENSDART00000165331
SPARC related modular calcium binding 2
chr3_+_36424055 0.58 ENSDART00000170318
si:ch1073-443f11.2
chr5_-_67471375 0.56 ENSDART00000147009
si:dkey-251i10.2
chr11_+_14622379 0.55 ENSDART00000112589
ephrin-A2b
chr4_-_11737939 0.55 ENSDART00000150299
podocalyxin-like
chr11_-_1509773 0.55 ENSDART00000050762
phosphatase and actin regulator 3b
chr9_-_48371379 0.54 ENSDART00000115121
collagen, type XXVIII, alpha 2a
chr16_-_43344859 0.54 ENSDART00000058680
proteasome subunit alpha 2
chr13_-_1408775 0.54 ENSDART00000049684
BCL2 associated athanogene 2
chr3_-_41795917 0.53 ENSDART00000182662
galectin-related inter-fiber protein
chr16_+_43344475 0.52 ENSDART00000085282
mitochondrial ribosomal protein L32
chr13_+_29778610 0.52 ENSDART00000132004
paired box 2a
chr21_-_26071773 0.52 ENSDART00000141382
RAB34, member RAS oncogene family b
chr8_+_29986265 0.51 ENSDART00000148258
patched 1
chr11_+_8565323 0.49 ENSDART00000081607
ENSDART00000141612
transducin (beta)-like 1 X-linked receptor 1a
chr4_-_18595525 0.49 ENSDART00000049061
cyclin-dependent kinase inhibitor 1Ba
chr5_-_63509581 0.48 ENSDART00000097325
complement component 5
chr23_+_42482137 0.47 ENSDART00000160199
cytochrome P450, family 2, subfamily AA, polypeptide 3
chr21_-_5958387 0.47 ENSDART00000130521
si:ch73-209e20.5
chr19_+_43396861 0.47 ENSDART00000151433
Yes-related kinase
chr19_+_5072918 0.47 ENSDART00000037126
enolase 2
chr4_-_22311610 0.46 ENSDART00000137814
hematopoietic cell-specific Lyn substrate 1
chr13_+_19322686 0.46 ENSDART00000058036
empty spiracles homeobox 2
chr12_+_30586599 0.46 ENSDART00000124920
ENSDART00000126984
nebulin-related anchoring protein
chr11_+_8565828 0.45 ENSDART00000126523
transducin (beta)-like 1 X-linked receptor 1a
chr11_-_25418856 0.45 ENSDART00000013714
GATA binding protein 1a
chr23_+_36106790 0.44 ENSDART00000128533
homeobox C3a
chr14_+_25465346 0.44 ENSDART00000173436
si:dkey-280e21.3
chr5_+_29820266 0.44 ENSDART00000146331
ENSDART00000098315
F11 receptor, tandem duplicate 2
chr6_-_11768198 0.44 ENSDART00000183463
membrane-associated ring finger (C3HC4) 7
chr6_-_18976168 0.44 ENSDART00000170039
septin 9b
chr23_-_15284757 0.43 ENSDART00000139135
sulfatase 2b
chr7_+_67467702 0.43 ENSDART00000168460
ENSDART00000170322
ribosomal protein L13
chr8_+_52619365 0.42 ENSDART00000162953
cysteine-rich, angiogenic inducer, 61 like 2
chr23_-_11870962 0.42 ENSDART00000143481
si:dkey-178k16.1
chr2_+_55982300 0.41 ENSDART00000183903
nicotinamide riboside kinase 2
chr6_-_58757131 0.40 ENSDART00000083582
sterol O-acyltransferase 2
chr9_-_42418470 0.40 ENSDART00000144353
calcitonin receptor-like a
chr5_+_29159777 0.40 ENSDART00000174702
ENSDART00000037891
dipeptidyl-peptidase 7
chr5_+_48683447 0.40 ENSDART00000008043
adhesion G protein-coupled receptor V1
chr23_+_45538932 0.40 ENSDART00000135602
si:ch73-290k24.6
chr22_+_9872323 0.40 ENSDART00000129240
si:dkey-253d23.4
chr25_+_5044780 0.39 ENSDART00000153980
parvin, beta
chr2_+_24188502 0.39 ENSDART00000181955
ENSDART00000191706
ENSDART00000125909
microtubule associated protein 4 like
chr4_+_25223050 0.38 ENSDART00000138121
inter-alpha-trypsin inhibitor heavy chain family, member 5
chr16_+_12836143 0.38 ENSDART00000067741
calcium channel, voltage-dependent, gamma subunit 6b
chr16_-_31754102 0.38 ENSDART00000185043
protein tyrosine phosphatase, non-receptor type 6
chr20_+_4060839 0.36 ENSDART00000178565
tripartite motif containing 67
chr2_+_50862527 0.36 ENSDART00000169800
ENSDART00000158847
ENSDART00000160900
adenylate cyclase activating polypeptide 1a (pituitary) receptor type I
chr24_+_24831727 0.36 ENSDART00000080969
tripartite motif containing 55b
chr21_+_17880511 0.35 ENSDART00000080481
retinoid X receptor, alpha a
chr20_+_26966725 0.35 ENSDART00000029781
AHA1, activator of heat shock protein ATPase homolog 1a
chr5_-_9073433 0.35 ENSDART00000099891
ATP synthase membrane subunit eb
chr14_+_11458044 0.34 ENSDART00000186425
si:ch211-153b23.5
chr12_+_18681477 0.34 ENSDART00000127981
ENSDART00000143979
regulator of G protein signaling 9b
chr14_+_22113331 0.34 ENSDART00000109759
thioredoxin-related transmembrane protein 2a
chr2_+_33382648 0.34 ENSDART00000137207
ENSDART00000098831
solute carrier family 6 (neurotransmitter transporter, glycine), member 9
chr16_+_23960744 0.33 ENSDART00000058965
apolipoprotein Eb
chr11_-_2131280 0.33 ENSDART00000008409
calcium binding and coiled-coil domain 1b
chr21_+_26071874 0.33 ENSDART00000003001
ENSDART00000146573
ribosomal protein L23a
chr3_-_12930217 0.33 ENSDART00000166322
platelet-derived growth factor alpha polypeptide b
chr24_-_37287792 0.33 ENSDART00000166086

chr15_+_36966369 0.33 ENSDART00000163622
kirre like nephrin family adhesion molecule 3, like
chr14_-_11456724 0.33 ENSDART00000110424
si:ch211-153b23.4
chr1_-_58963395 0.32 ENSDART00000130415

chr19_-_38611814 0.32 ENSDART00000151958
collagen, type XVI, alpha 1
chr23_-_45539306 0.32 ENSDART00000161913

chr1_-_10647307 0.32 ENSDART00000103548
si:dkey-31e10.1
chr15_-_2188332 0.32 ENSDART00000138941
ENSDART00000009564
short stature homeobox 2
chr3_+_36284986 0.32 ENSDART00000059533
WD repeat domain, phosphoinositide interacting 1
chr5_+_51026563 0.31 ENSDART00000050988
glucosaminyl (N-acetyl) transferase 4, core 2, a
chr24_+_23742690 0.31 ENSDART00000130162
transcription factor 24
chr16_+_5184402 0.31 ENSDART00000156685
SOGA family member 3a
chr17_-_21441464 0.31 ENSDART00000031490
ventral anterior homeobox 1
chr20_-_8094718 0.31 ENSDART00000122902
si:ch211-232i5.3
chr12_-_36740781 0.30 ENSDART00000105484
si:ch211-216b21.2
chr4_-_8014463 0.30 ENSDART00000036153
coiled-coil domain containing 3a
chr12_-_28570989 0.30 ENSDART00000008010
pyruvate dehydrogenase kinase, isozyme 2a
chr16_-_27174373 0.30 ENSDART00000166681
ferric-chelate reductase 1-like
chr1_+_25801648 0.30 ENSDART00000129471
guanylate cyclase 1 soluble subunit beta 1
chr5_+_65871688 0.30 ENSDART00000175217
family with sequence similarity 163 member B
chr5_+_29160132 0.29 ENSDART00000088827
dipeptidyl-peptidase 7
chr9_-_1703761 0.29 ENSDART00000144822
ENSDART00000137210
ENSDART00000135273
heterogeneous nuclear ribonucleoprotein A3
chr21_-_26071142 0.29 ENSDART00000004740
RAB34, member RAS oncogene family b
chr12_-_48477031 0.29 ENSDART00000105176
NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 8
chr21_-_5205617 0.29 ENSDART00000145554
ENSDART00000045284
ribosomal protein L37
chr16_+_34479064 0.29 ENSDART00000159965
si:ch211-255i3.4
chr25_-_18140305 0.28 ENSDART00000180222
kit ligand a
chr12_+_17504559 0.28 ENSDART00000020628
cytohesin 3a
chr21_-_5881344 0.28 ENSDART00000009241
ribosomal protein L35
chr6_+_32497493 0.28 ENSDART00000184819
KN motif and ankyrin repeat domains 4
chr25_+_3677650 0.28 ENSDART00000154348
prion protein, related sequence 3
chr1_-_10647484 0.27 ENSDART00000164541
ENSDART00000188958
ENSDART00000190904
si:dkey-31e10.1
chr4_+_391297 0.27 ENSDART00000030215
ribosomal protein L18a
chr11_-_30158191 0.27 ENSDART00000155278
ENSDART00000156121
Scm polycomb group protein like 2
chr10_-_13239367 0.26 ENSDART00000001253
si:busm1-57f23.1
chr10_+_21576909 0.26 ENSDART00000168604
ENSDART00000166533
protocadherin 1 alpha 3
chr5_+_29160324 0.26 ENSDART00000137324
dipeptidyl-peptidase 7
chr17_-_49978986 0.26 ENSDART00000154728
collagen, type XII, alpha 1a
chr18_-_17030870 0.26 ENSDART00000079817
hyaluronan synthase 3
chr25_-_16755340 0.26 ENSDART00000124729
ENSDART00000110859
RIB43A domain with coiled-coils 2
chr25_-_8030425 0.25 ENSDART00000014964
calcium/calmodulin-dependent protein kinase 1Db
chr8_-_13972626 0.25 ENSDART00000144296
serpin peptidase inhibitor, clade G (C1 inhibitor), member 1
chr1_+_21725821 0.25 ENSDART00000132602
paired box 5
chr10_-_20524592 0.25 ENSDART00000185048
DDHD domain containing 2
chr21_-_41025340 0.25 ENSDART00000148231
PLAC8-like 1
chr20_+_1960092 0.25 ENSDART00000191892

chr13_+_30903816 0.25 ENSDART00000191727
excision repair cross-complementation group 6
chr20_-_4766645 0.25 ENSDART00000147071
ENSDART00000152398
adenylate kinase 7a
chr16_+_16969060 0.25 ENSDART00000182819
ENSDART00000191876
si:ch211-120k19.1
ribosomal protein L18
chr13_-_37636147 0.25 ENSDART00000144065
si:dkey-188i13.8
chr16_+_54780544 0.25 ENSDART00000126646
si:zfos-1192g2.3
chr7_-_9803154 0.25 ENSDART00000055593
aldehyde dehydrogenase 1 family, member A3
chr1_+_55293424 0.25 ENSDART00000152464
zgc:172106
chr15_+_14202114 0.24 ENSDART00000169369
si:dkey-243k1.3
chr6_-_10753504 0.24 ENSDART00000045299
ENSDART00000165645
Obg-like ATPase 1
chr10_-_35236949 0.24 ENSDART00000145804
yippee-like 2a
chr10_-_20339113 0.24 ENSDART00000144378
ENSDART00000098600
zinc finger, matrin-type 4b
chr14_-_2001386 0.24 ENSDART00000170346
ENSDART00000163975
protocadherin 2 gamma 5
chr22_-_12746539 0.24 ENSDART00000175374
phospholipase C, delta 4a
chr14_+_36869273 0.24 ENSDART00000111674
si:ch211-132p1.2
chr15_+_28355023 0.24 ENSDART00000122159
si:dkey-118k5.3
chr7_+_25858380 0.24 ENSDART00000148780
ENSDART00000079218
myotubularin related protein 1a
chr1_+_51721851 0.24 ENSDART00000040397
peroxiredoxin 2
chrM_+_11009 0.23 ENSDART00000093617
NADH dehydrogenase 4L, mitochondrial
chr1_+_45085194 0.23 ENSDART00000193863
si:ch211-151p13.8
chr15_+_9053059 0.23 ENSDART00000012039
protein phosphatase, Mg2+/Mn2+ dependent, 1Na (putative)
chr15_-_2632891 0.23 ENSDART00000081840
claudin j
chr11_+_43431289 0.23 ENSDART00000192526
solute carrier family 29 (equilibrative nucleoside transporter), member 1b
chr10_+_8730988 0.23 ENSDART00000145596
integrin, alpha 1
chr23_-_45705525 0.23 ENSDART00000148959
endothelin receptor type Ab
chr1_-_44701313 0.22 ENSDART00000193926
si:dkey-28b4.8
chr12_+_28854410 0.22 ENSDART00000152991
nuclear factor, erythroid 2-like 1b
chr2_-_51644044 0.22 ENSDART00000157899
defender against cell death 1
chr19_+_1831911 0.22 ENSDART00000166653
protein tyrosine kinase 2aa
chr22_+_17205608 0.22 ENSDART00000181267
RAB3B, member RAS oncogene family
chr16_+_11834516 0.22 ENSDART00000146611
chemokine (C-X-C motif) receptor 3, tandem duplicate 3
chr19_-_10810006 0.22 ENSDART00000151157
si:dkey-3n22.9
chr15_+_33865312 0.21 ENSDART00000166141
tektin 1
chr25_-_10565006 0.21 ENSDART00000130608
ENSDART00000190212
galanin/GMAP prepropeptide
chr20_-_22476255 0.21 ENSDART00000103510
platelet-derived growth factor receptor, alpha polypeptide
chr7_+_48705227 0.21 ENSDART00000174034

chr6_-_33023745 0.21 ENSDART00000156211
adenylate cyclase activating polypeptide 1b (pituitary) receptor type I
chr14_-_30387894 0.21 ENSDART00000176136
solute carrier family 7 (cationic amino acid transporter, y+ system), member 2
chr9_-_31596016 0.21 ENSDART00000142289
sodium leak channel, non-selective
chr24_-_40860603 0.21 ENSDART00000188032

chr10_+_4874542 0.21 ENSDART00000101431
paralemmin 2
chr12_+_13652361 0.21 ENSDART00000182757
ENSDART00000152689
5-oxoprolinase, ATP-hydrolysing
chr8_-_10932206 0.21 ENSDART00000124313
nuclear receptor subfamily 1, group H, member 5
chr8_+_34624025 0.21 ENSDART00000180772

chr3_+_59784632 0.21 ENSDART00000084729
platelet/endothelial cell adhesion molecule 1
chr7_+_8456999 0.21 ENSDART00000172880
jacalin 4
chr16_+_14588141 0.21 ENSDART00000140469
ENSDART00000059984
ENSDART00000167411
ENSDART00000133566
DEP domain containing MTOR-interacting protein
chr25_+_31267268 0.21 ENSDART00000181239
troponin I type 2a (skeletal, fast), tandem duplicate 3
chr9_-_8661436 0.21 ENSDART00000130442
collagen, type IV, alpha 1
chr10_+_16092671 0.21 ENSDART00000182761
ENSDART00000154835
multiple EGF-like-domains 10
chr2_-_30324610 0.20 ENSDART00000185422
junctophilin 1b
chr25_+_13731542 0.20 ENSDART00000161012
coiled-coil domain containing 135
chr2_+_10709557 0.20 ENSDART00000183118
ENSDART00000109723
ecotropic viral integration site 5a
chr1_+_56463494 0.20 ENSDART00000097964
zgc:171452
chr25_+_26895394 0.20 ENSDART00000155820
si:dkey-42p14.3
chr2_+_35854242 0.20 ENSDART00000134918
DEAH (Asp-Glu-Ala-His) box helicase 9
chr3_-_39152478 0.20 ENSDART00000154550
si:dkeyp-57f11.2
chr14_-_33218418 0.20 ENSDART00000163046
si:dkey-31j3.11
chr6_+_27062512 0.19 ENSDART00000168277
ENSDART00000149429
BOK, BCL2 family apoptosis regulator a
chr16_-_51888952 0.19 ENSDART00000186407
ENSDART00000175435
ribosomal protein L28
chr11_+_2506516 0.19 ENSDART00000130886
ENSDART00000189767
si:ch73-190f16.2
chr18_+_7286788 0.19 ENSDART00000022998
si:ch73-86n2.1
chr13_+_4368504 0.19 ENSDART00000108935
SFT2 domain containing 1
chr22_-_1245226 0.19 ENSDART00000161292
adenosine monophosphate deaminase 2a
chr7_+_69905307 0.18 ENSDART00000035907
SEC24 homolog D, COPII coat complex component
chr19_-_2861444 0.18 ENSDART00000169053
C-type lectin domain family 3, member Bb
chr7_-_71758307 0.18 ENSDART00000161067
ENSDART00000165253
myomesin 1b
chr3_-_58116314 0.18 ENSDART00000154901
si:ch211-256e16.6
chr10_+_31248036 0.18 ENSDART00000193574
roundabout, axon guidance receptor, homolog 4 (Drosophila)
chr5_+_24245682 0.17 ENSDART00000049003
ATPase H+ transporting V1 subunit Aa
chr12_-_3753131 0.17 ENSDART00000129668
family with sequence similarity 57, member Bb
chr16_+_20161805 0.17 ENSDART00000192146
chromosome 16 C2orf66 homolog

Network of associatons between targets according to the STRING database.

First level regulatory network of meox2a

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 1.0 GO:0043152 induction of bacterial agglutination(GO:0043152)
0.2 0.5 GO:0033631 cell-cell adhesion mediated by integrin(GO:0033631) regulation of cell-cell adhesion mediated by integrin(GO:0033632)
0.1 1.2 GO:0060118 vestibular receptor cell differentiation(GO:0060114) vestibular receptor cell development(GO:0060118)
0.1 1.2 GO:0034433 steroid esterification(GO:0034433) sterol esterification(GO:0034434) cholesterol esterification(GO:0034435)
0.1 0.4 GO:0097264 self proteolysis(GO:0097264)
0.1 0.4 GO:0030224 monocyte differentiation(GO:0030224)
0.1 0.3 GO:0071831 high-density lipoprotein particle assembly(GO:0034380) chylomicron remnant clearance(GO:0034382) triglyceride-rich lipoprotein particle clearance(GO:0071830) intermediate-density lipoprotein particle clearance(GO:0071831)
0.1 0.8 GO:0090385 phagosome-lysosome fusion(GO:0090385)
0.1 0.3 GO:0030213 hyaluronan biosynthetic process(GO:0030213)
0.1 0.3 GO:2000257 regulation of protein activation cascade(GO:2000257)
0.1 0.3 GO:0060092 regulation of synaptic transmission, glycinergic(GO:0060092)
0.1 0.2 GO:0090069 regulation of ribosome biogenesis(GO:0090069)
0.1 0.2 GO:1904088 regulation of convergent extension involved in axis elongation(GO:1901232) positive regulation of epiboly involved in gastrulation with mouth forming second(GO:1904088)
0.1 0.3 GO:0090259 regulation of retinal ganglion cell axon guidance(GO:0090259)
0.1 0.4 GO:0061577 calcium ion transmembrane transport via high voltage-gated calcium channel(GO:0061577) regulation of calcium ion transmembrane transport via high voltage-gated calcium channel(GO:1902514)
0.1 0.5 GO:0071691 cardiac muscle thin filament assembly(GO:0071691)
0.1 0.3 GO:0099543 trans-synaptic signaling by soluble gas(GO:0099543) trans-synaptic signaling by nitric oxide(GO:0099548)
0.1 0.5 GO:0045736 negative regulation of cyclin-dependent protein serine/threonine kinase activity(GO:0045736) negative regulation of cyclin-dependent protein kinase activity(GO:1904030)
0.1 0.1 GO:0033630 positive regulation of cell adhesion mediated by integrin(GO:0033630)
0.1 0.2 GO:0070278 extracellular matrix constituent secretion(GO:0070278)
0.1 0.2 GO:0001954 positive regulation of cell-matrix adhesion(GO:0001954)
0.1 0.5 GO:0032889 regulation of vacuole fusion, non-autophagic(GO:0032889)
0.1 0.5 GO:0048635 negative regulation of muscle organ development(GO:0048635)
0.1 0.3 GO:0021731 trigeminal motor nucleus development(GO:0021731)
0.1 0.6 GO:0051491 positive regulation of filopodium assembly(GO:0051491)
0.0 0.3 GO:0021877 forebrain neuron fate commitment(GO:0021877)
0.0 0.3 GO:2000480 negative regulation of cAMP-dependent protein kinase activity(GO:2000480)
0.0 0.3 GO:0031954 positive regulation of protein autophosphorylation(GO:0031954)
0.0 0.2 GO:0031174 lifelong otolith mineralization(GO:0031174)
0.0 0.2 GO:0003319 cardioblast migration to the midline involved in heart rudiment formation(GO:0003319)
0.0 0.6 GO:0090303 positive regulation of wound healing(GO:0090303)
0.0 0.2 GO:0003261 cardiac muscle progenitor cell migration to the midline involved in heart field formation(GO:0003261) heart rudiment formation(GO:0003315)
0.0 2.1 GO:0003009 skeletal muscle contraction(GO:0003009)
0.0 0.6 GO:0033173 calcineurin-NFAT signaling cascade(GO:0033173)
0.0 0.2 GO:1903251 multi-ciliated epithelial cell differentiation(GO:1903251)
0.0 0.2 GO:0015862 uridine transport(GO:0015862) pyrimidine nucleoside transport(GO:0015864)
0.0 0.1 GO:0099538 synaptic signaling via neuropeptide(GO:0099538) trans-synaptic signaling by neuropeptide(GO:0099540) trans-synaptic signaling by neuropeptide, modulating synaptic transmission(GO:0099551) cellular response to brain-derived neurotrophic factor stimulus(GO:1990416)
0.0 0.3 GO:0006283 transcription-coupled nucleotide-excision repair(GO:0006283)
0.0 0.2 GO:0090467 L-arginine import(GO:0043091) amino acid import across plasma membrane(GO:0089718) arginine import(GO:0090467) L-arginine import across plasma membrane(GO:0097638) L-arginine transport(GO:1902023) L-arginine import into cell(GO:1902765) amino acid import into cell(GO:1902837) L-arginine transmembrane transport(GO:1903400) arginine transmembrane transport(GO:1903826)
0.0 0.3 GO:0006450 regulation of translational fidelity(GO:0006450)
0.0 0.3 GO:0032781 positive regulation of ATPase activity(GO:0032781)
0.0 0.4 GO:0050892 intestinal absorption(GO:0050892)
0.0 0.4 GO:0035860 esophagus smooth muscle contraction(GO:0014846) glial cell-derived neurotrophic factor receptor signaling pathway(GO:0035860)
0.0 0.2 GO:0014707 branchiomeric skeletal muscle development(GO:0014707)
0.0 0.2 GO:1904668 positive regulation of ubiquitin protein ligase activity(GO:1904668)
0.0 0.6 GO:0030316 osteoclast differentiation(GO:0030316)
0.0 0.4 GO:0030212 hyaluronan metabolic process(GO:0030212)
0.0 0.2 GO:0000303 response to superoxide(GO:0000303) response to oxygen radical(GO:0000305) removal of superoxide radicals(GO:0019430) cellular response to oxygen radical(GO:0071450) cellular response to superoxide(GO:0071451) cellular oxidant detoxification(GO:0098869) cellular detoxification(GO:1990748)
0.0 0.1 GO:0060829 negative regulation of canonical Wnt signaling pathway involved in neural plate anterior/posterior pattern formation(GO:0060829)
0.0 0.1 GO:0046084 adenine metabolic process(GO:0046083) adenine biosynthetic process(GO:0046084)
0.0 0.1 GO:0006572 tyrosine catabolic process(GO:0006572)
0.0 0.6 GO:0055064 chloride ion homeostasis(GO:0055064)
0.0 0.3 GO:0032836 glomerular basement membrane development(GO:0032836)
0.0 0.3 GO:0036065 fucosylation(GO:0036065)
0.0 0.7 GO:0050868 negative regulation of T cell activation(GO:0050868) negative regulation of leukocyte cell-cell adhesion(GO:1903038)
0.0 0.4 GO:0030032 lamellipodium assembly(GO:0030032)
0.0 0.5 GO:0048246 macrophage chemotaxis(GO:0048246)
0.0 0.6 GO:0042476 odontogenesis(GO:0042476)
0.0 0.1 GO:0034498 early endosome to Golgi transport(GO:0034498)
0.0 0.9 GO:0060028 convergent extension involved in axis elongation(GO:0060028)
0.0 0.1 GO:0032917 polyamine acetylation(GO:0032917) spermidine acetylation(GO:0032918)
0.0 0.6 GO:0010499 proteasomal ubiquitin-independent protein catabolic process(GO:0010499)
0.0 0.3 GO:0032981 NADH dehydrogenase complex assembly(GO:0010257) mitochondrial respiratory chain complex I assembly(GO:0032981) mitochondrial respiratory chain complex I biogenesis(GO:0097031)
0.0 0.2 GO:0032264 IMP salvage(GO:0032264)
0.0 0.2 GO:0007172 signal complex assembly(GO:0007172)
0.0 0.1 GO:0015990 energy coupled proton transmembrane transport, against electrochemical gradient(GO:0015988) electron transport coupled proton transport(GO:0015990)
0.0 0.3 GO:0000463 maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000463)
0.0 0.1 GO:0006531 aspartate metabolic process(GO:0006531)
0.0 0.1 GO:0039528 cytoplasmic pattern recognition receptor signaling pathway in response to virus(GO:0039528) cellular response to virus(GO:0098586)
0.0 0.3 GO:0006120 mitochondrial electron transport, NADH to ubiquinone(GO:0006120)
0.0 0.4 GO:0035622 intrahepatic bile duct development(GO:0035622)
0.0 0.9 GO:0016575 histone deacetylation(GO:0016575)
0.0 0.2 GO:0015014 heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process(GO:0015014)
0.0 0.5 GO:0050821 protein stabilization(GO:0050821)
0.0 0.3 GO:0000027 ribosomal large subunit assembly(GO:0000027)
0.0 0.3 GO:0015985 energy coupled proton transport, down electrochemical gradient(GO:0015985) ATP synthesis coupled proton transport(GO:0015986)
0.0 0.1 GO:0071423 thiosulfate transport(GO:0015709) oxaloacetate transport(GO:0015729) malate transport(GO:0015743) succinate transport(GO:0015744) succinate transmembrane transport(GO:0071422) malate transmembrane transport(GO:0071423)
0.0 0.1 GO:0007288 sperm axoneme assembly(GO:0007288)
0.0 0.2 GO:0030317 sperm motility(GO:0030317)
0.0 0.3 GO:0070570 regulation of axon regeneration(GO:0048679) regulation of neuron projection regeneration(GO:0070570)
0.0 0.1 GO:1903672 positive regulation of sprouting angiogenesis(GO:1903672)
0.0 0.2 GO:0014068 positive regulation of phosphatidylinositol 3-kinase signaling(GO:0014068)
0.0 0.1 GO:0061484 hematopoietic stem cell homeostasis(GO:0061484)
0.0 0.6 GO:0046928 regulation of neurotransmitter secretion(GO:0046928)
0.0 0.1 GO:0031643 positive regulation of myelination(GO:0031643) positive regulation of neurological system process(GO:0031646)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.6 GO:0005955 calcineurin complex(GO:0005955)
0.1 0.4 GO:0060171 stereocilium membrane(GO:0060171)
0.1 0.3 GO:0034363 intermediate-density lipoprotein particle(GO:0034363)
0.1 0.5 GO:0000015 phosphopyruvate hydratase complex(GO:0000015)
0.1 0.5 GO:0031528 microvillus membrane(GO:0031528)
0.1 0.4 GO:1990454 L-type voltage-gated calcium channel complex(GO:1990454)
0.0 2.1 GO:0005861 troponin complex(GO:0005861)
0.0 0.5 GO:0019773 proteasome core complex, alpha-subunit complex(GO:0019773)
0.0 0.2 GO:0030314 junctional membrane complex(GO:0030314)
0.0 0.3 GO:0034045 pre-autophagosomal structure membrane(GO:0034045)
0.0 0.7 GO:0043195 terminal bouton(GO:0043195)
0.0 1.8 GO:0022625 cytosolic large ribosomal subunit(GO:0022625)
0.0 0.3 GO:0000276 mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)(GO:0000276)
0.0 0.2 GO:0005663 DNA replication factor C complex(GO:0005663)
0.0 2.0 GO:0005581 collagen trimer(GO:0005581)
0.0 1.8 GO:0030018 Z disc(GO:0030018)
0.0 0.7 GO:0045271 mitochondrial respiratory chain complex I(GO:0005747) NADH dehydrogenase complex(GO:0030964) respiratory chain complex I(GO:0045271)
0.0 0.2 GO:0031588 nucleotide-activated protein kinase complex(GO:0031588)
0.0 0.2 GO:0008250 oligosaccharyltransferase complex(GO:0008250)
0.0 0.8 GO:0031225 anchored component of membrane(GO:0031225)
0.0 0.5 GO:0000315 organellar large ribosomal subunit(GO:0000315) mitochondrial large ribosomal subunit(GO:0005762)
0.0 0.9 GO:0030427 site of polarized growth(GO:0030427)
0.0 0.0 GO:0031510 SUMO activating enzyme complex(GO:0031510)
0.0 0.4 GO:0005940 septin ring(GO:0005940) septin complex(GO:0031105) septin cytoskeleton(GO:0032156)
0.0 0.2 GO:0033017 sarcoplasmic reticulum membrane(GO:0033017)
0.0 0.5 GO:0008305 integrin complex(GO:0008305)
0.0 0.1 GO:0005964 phosphorylase kinase complex(GO:0005964)
0.0 0.4 GO:0030175 filopodium(GO:0030175)
0.0 0.2 GO:0031594 neuromuscular junction(GO:0031594)
0.0 0.2 GO:0033180 proton-transporting V-type ATPase, V1 domain(GO:0033180)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.2 GO:0004772 sterol O-acyltransferase activity(GO:0004772) cholesterol O-acyltransferase activity(GO:0034736)
0.2 0.5 GO:0048030 disaccharide binding(GO:0048030)
0.1 0.4 GO:0001635 adrenomedullin receptor activity(GO:0001605) calcitonin gene-related peptide receptor activity(GO:0001635)
0.1 0.5 GO:0097108 hedgehog family protein binding(GO:0097108)
0.1 0.3 GO:0043395 heparan sulfate proteoglycan binding(GO:0043395)
0.1 1.1 GO:0051373 telethonin binding(GO:0031433) FATZ binding(GO:0051373)
0.1 0.6 GO:0004723 calcium-dependent protein serine/threonine phosphatase activity(GO:0004723) calmodulin-dependent protein phosphatase activity(GO:0033192)
0.1 0.4 GO:0005173 stem cell factor receptor binding(GO:0005173)
0.1 0.5 GO:0043023 ribosomal large subunit binding(GO:0043023)
0.1 0.6 GO:0016936 galactoside binding(GO:0016936)
0.1 0.5 GO:0004861 cyclin-dependent protein serine/threonine kinase inhibitor activity(GO:0004861)
0.1 0.4 GO:0004999 vasoactive intestinal polypeptide receptor activity(GO:0004999)
0.1 0.5 GO:0004634 phosphopyruvate hydratase activity(GO:0004634)
0.1 0.4 GO:0050262 ribosylnicotinamide kinase activity(GO:0050262)
0.1 0.5 GO:0000774 adenyl-nucleotide exchange factor activity(GO:0000774)
0.1 1.0 GO:0008239 dipeptidyl-peptidase activity(GO:0008239)
0.1 0.2 GO:0005017 platelet-derived growth factor-activated receptor activity(GO:0005017) platelet-derived growth factor binding(GO:0048407)
0.1 0.6 GO:0004157 dihydropyrimidinase activity(GO:0004157)
0.1 0.2 GO:0031716 calcitonin receptor binding(GO:0031716)
0.0 0.2 GO:0004127 cytidylate kinase activity(GO:0004127)
0.0 1.0 GO:0003785 actin monomer binding(GO:0003785)
0.0 0.3 GO:0030291 cAMP-dependent protein kinase inhibitor activity(GO:0004862) protein serine/threonine kinase inhibitor activity(GO:0030291)
0.0 0.4 GO:0008467 [heparan sulfate]-glucosamine 3-sulfotransferase 1 activity(GO:0008467)
0.0 0.3 GO:0005030 neurotrophin receptor activity(GO:0005030)
0.0 0.1 GO:0003868 4-hydroxyphenylpyruvate dioxygenase activity(GO:0003868)
0.0 0.3 GO:0004740 pyruvate dehydrogenase (acetyl-transferring) kinase activity(GO:0004740)
0.0 0.3 GO:0005161 platelet-derived growth factor receptor binding(GO:0005161)
0.0 0.1 GO:0016649 electron-transferring-flavoprotein dehydrogenase activity(GO:0004174) oxidoreductase activity, acting on the CH-NH group of donors, quinone or similar compound as acceptor(GO:0016649)
0.0 0.2 GO:0010997 anaphase-promoting complex binding(GO:0010997) ubiquitin ligase activator activity(GO:1990757)
0.0 0.2 GO:0008379 thioredoxin peroxidase activity(GO:0008379)
0.0 0.2 GO:0004962 endothelin receptor activity(GO:0004962)
0.0 0.4 GO:0010851 cyclase regulator activity(GO:0010851)
0.0 0.2 GO:0015189 L-lysine transmembrane transporter activity(GO:0015189)
0.0 0.2 GO:0016812 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides(GO:0016812)
0.0 0.1 GO:0035671 3-oxo-5-alpha-steroid 4-dehydrogenase activity(GO:0003865) steroid dehydrogenase activity, acting on the CH-CH group of donors(GO:0033765) enone reductase activity(GO:0035671) cholestenone 5-alpha-reductase activity(GO:0047751)
0.0 0.1 GO:0031530 gonadotropin hormone-releasing hormone activity(GO:0005183) gonadotropin-releasing hormone receptor binding(GO:0031530)
0.0 0.3 GO:0046920 alpha-(1->3)-fucosyltransferase activity(GO:0046920)
0.0 0.6 GO:0008137 NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136)
0.0 0.1 GO:0098639 C-X3-C chemokine binding(GO:0019960) protein binding involved in cell-matrix adhesion(GO:0098634) collagen binding involved in cell-matrix adhesion(GO:0098639)
0.0 0.1 GO:0004689 phosphorylase kinase activity(GO:0004689)
0.0 0.4 GO:0008449 N-acetylglucosamine-6-sulfatase activity(GO:0008449)
0.0 0.2 GO:0052629 phosphatidylinositol-3,5-bisphosphate 3-phosphatase activity(GO:0052629)
0.0 0.3 GO:0015187 glycine transmembrane transporter activity(GO:0015187)
0.0 0.2 GO:0015016 [heparan sulfate]-glucosamine N-sulfotransferase activity(GO:0015016)
0.0 0.2 GO:0022850 serotonin-gated cation channel activity(GO:0022850)
0.0 0.3 GO:0051879 Hsp90 protein binding(GO:0051879)
0.0 0.1 GO:0019809 spermidine binding(GO:0019809)
0.0 0.2 GO:0016286 small conductance calcium-activated potassium channel activity(GO:0016286)
0.0 0.2 GO:0004029 aldehyde dehydrogenase (NAD) activity(GO:0004029)
0.0 0.1 GO:0015288 porin activity(GO:0015288)
0.0 0.2 GO:0004563 beta-N-acetylhexosaminidase activity(GO:0004563)
0.0 0.2 GO:0047623 AMP deaminase activity(GO:0003876) adenosine-phosphate deaminase activity(GO:0047623)
0.0 0.5 GO:0050840 extracellular matrix binding(GO:0050840)
0.0 0.3 GO:0004383 guanylate cyclase activity(GO:0004383)
0.0 0.1 GO:0004069 L-aspartate:2-oxoglutarate aminotransferase activity(GO:0004069)
0.0 0.5 GO:0008157 protein phosphatase 1 binding(GO:0008157)
0.0 0.2 GO:0046933 proton-transporting ATP synthase activity, rotational mechanism(GO:0046933)
0.0 0.0 GO:0008022 protein C-terminus binding(GO:0008022)
0.0 0.1 GO:0048487 beta-tubulin binding(GO:0048487)
0.0 0.1 GO:0015131 thiosulfate transmembrane transporter activity(GO:0015117) oxaloacetate transmembrane transporter activity(GO:0015131) malate transmembrane transporter activity(GO:0015140)
0.0 0.4 GO:0005246 calcium channel regulator activity(GO:0005246)
0.0 0.2 GO:0016868 intramolecular transferase activity, phosphotransferases(GO:0016868)
0.0 0.2 GO:0033170 DNA clamp loader activity(GO:0003689) protein-DNA loading ATPase activity(GO:0033170)
0.0 0.5 GO:0017075 syntaxin-1 binding(GO:0017075)
0.0 0.1 GO:0051185 coenzyme transporter activity(GO:0051185)
0.0 0.2 GO:0008553 hydrogen-exporting ATPase activity, phosphorylative mechanism(GO:0008553)
0.0 0.1 GO:0071933 Arp2/3 complex binding(GO:0071933)
0.0 2.5 GO:0003735 structural constituent of ribosome(GO:0003735)
0.0 1.9 GO:0004866 endopeptidase inhibitor activity(GO:0004866)
0.0 0.1 GO:0016316 phosphatidylinositol-3,4-bisphosphate 4-phosphatase activity(GO:0016316)
0.0 0.8 GO:0004715 non-membrane spanning protein tyrosine kinase activity(GO:0004715)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.6 PID TCR CALCIUM PATHWAY Calcium signaling in the CD4+ TCR pathway
0.0 1.0 NABA PROTEOGLYCANS Genes encoding proteoglycans
0.0 0.2 PID THROMBIN PAR4 PATHWAY PAR4-mediated thrombin signaling events
0.0 0.5 PID HEDGEHOG 2PATHWAY Signaling events mediated by the Hedgehog family
0.0 0.6 PID FCER1 PATHWAY Fc-epsilon receptor I signaling in mast cells
0.0 1.1 PID CD8 TCR PATHWAY TCR signaling in naïve CD8+ T cells
0.0 0.1 ST JAK STAT PATHWAY Jak-STAT Pathway
0.0 0.2 PID LYMPH ANGIOGENESIS PATHWAY VEGFR3 signaling in lymphatic endothelium
0.0 0.4 PID INTEGRIN3 PATHWAY Beta3 integrin cell surface interactions
0.0 0.2 PID PDGFRA PATHWAY PDGFR-alpha signaling pathway
0.0 0.1 PID ERBB NETWORK PATHWAY ErbB receptor signaling network
0.0 0.3 NABA COLLAGENS Genes encoding collagen proteins

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.4 REACTOME PD1 SIGNALING Genes involved in PD-1 signaling
0.1 0.7 REACTOME PHOSPHORYLATION OF CD3 AND TCR ZETA CHAINS Genes involved in Phosphorylation of CD3 and TCR zeta chains
0.1 1.0 REACTOME KERATAN SULFATE DEGRADATION Genes involved in Keratan sulfate degradation
0.1 0.6 REACTOME CRMPS IN SEMA3A SIGNALING Genes involved in CRMPs in Sema3A signaling
0.0 0.3 REACTOME HYALURONAN METABOLISM Genes involved in Hyaluronan metabolism
0.0 0.2 REACTOME PECAM1 INTERACTIONS Genes involved in PECAM1 interactions
0.0 1.0 REACTOME ASSOCIATION OF TRIC CCT WITH TARGET PROTEINS DURING BIOSYNTHESIS Genes involved in Association of TriC/CCT with target proteins during biosynthesis
0.0 0.4 REACTOME DARPP 32 EVENTS Genes involved in DARPP-32 events
0.0 0.3 REACTOME NA CL DEPENDENT NEUROTRANSMITTER TRANSPORTERS Genes involved in Na+/Cl- dependent neurotransmitter transporters
0.0 2.0 REACTOME PEPTIDE CHAIN ELONGATION Genes involved in Peptide chain elongation
0.0 0.2 REACTOME PRESYNAPTIC NICOTINIC ACETYLCHOLINE RECEPTORS Genes involved in Presynaptic nicotinic acetylcholine receptors
0.0 0.5 REACTOME COMPLEMENT CASCADE Genes involved in Complement cascade
0.0 0.1 REACTOME DEGRADATION OF THE EXTRACELLULAR MATRIX Genes involved in Degradation of the extracellular matrix
0.0 0.3 REACTOME INTRINSIC PATHWAY Genes involved in Intrinsic Pathway
0.0 0.2 REACTOME OTHER SEMAPHORIN INTERACTIONS Genes involved in Other semaphorin interactions
0.0 0.2 REACTOME GLUTATHIONE CONJUGATION Genes involved in Glutathione conjugation
0.0 0.2 REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS Genes involved in Cell-extracellular matrix interactions
0.0 0.1 REACTOME HORMONE LIGAND BINDING RECEPTORS Genes involved in Hormone ligand-binding receptors
0.0 0.6 REACTOME CROSS PRESENTATION OF SOLUBLE EXOGENOUS ANTIGENS ENDOSOMES Genes involved in Cross-presentation of soluble exogenous antigens (endosomes)
0.0 0.6 REACTOME CLASS B 2 SECRETIN FAMILY RECEPTORS Genes involved in Class B/2 (Secretin family receptors)
0.0 0.1 REACTOME ANDROGEN BIOSYNTHESIS Genes involved in Androgen biosynthesis
0.0 0.1 REACTOME ACYL CHAIN REMODELLING OF PI Genes involved in Acyl chain remodelling of PI
0.0 0.2 REACTOME GLYCOGEN BREAKDOWN GLYCOGENOLYSIS Genes involved in Glycogen breakdown (glycogenolysis)
0.0 0.2 REACTOME THROMBIN SIGNALLING THROUGH PROTEINASE ACTIVATED RECEPTORS PARS Genes involved in Thrombin signalling through proteinase activated receptors (PARs)
0.0 0.5 REACTOME COLLAGEN FORMATION Genes involved in Collagen formation
0.0 0.0 REACTOME REGULATION OF RHEB GTPASE ACTIVITY BY AMPK Genes involved in Regulation of Rheb GTPase activity by AMPK
0.0 0.1 REACTOME SHC1 EVENTS IN EGFR SIGNALING Genes involved in SHC1 events in EGFR signaling
0.0 0.2 REACTOME POL SWITCHING Genes involved in Polymerase switching