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PRJNA195909:zebrafish embryo and larva development

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Results for maza+mazb

Z-value: 4.32

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Transcription factors associated with maza+mazb

Gene Symbol Gene ID Gene Info
ENSDARG00000063555 si_ch211-166g5.4
ENSDARG00000087330 MYC-associated zinc finger protein a (purine-binding transcription factor)

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
si:ch211-166g5.4dr11_v1_chr12_-_3778848_3778848-0.694.2e-02Click!
mazadr11_v1_chr3_-_21118969_21118969-0.561.2e-01Click!

Activity profile of maza+mazb motif

Sorted Z-values of maza+mazb motif

Promoter Log-likelihood Transcript Gene Gene Info
chr2_-_44183451 8.83 ENSDART00000111246
cell adhesion molecule 3
chr2_-_44183613 8.77 ENSDART00000079596
cell adhesion molecule 3
chr18_-_16123222 8.11 ENSDART00000061189
sarcospan (Kras oncogene-associated gene)
chr1_-_39943596 7.95 ENSDART00000149730
storkhead box 2a
chr21_+_26697536 6.53 ENSDART00000004109
guanine nucleotide binding protein (G protein), gamma 3
chr10_-_44026369 6.50 ENSDART00000185456
crystallin, beta B1
chr19_-_5254699 6.11 ENSDART00000081951
syntaxin 1B
chr14_-_9522364 5.75 ENSDART00000054689
atonal bHLH transcription factor 8
chr3_-_61162750 5.58 ENSDART00000055064
parvalbumin 8
chr7_+_36552725 5.25 ENSDART00000173682
chromodomain helicase DNA binding protein 9
chr5_-_14326959 5.05 ENSDART00000137355
tet methylcytosine dioxygenase 3
chr21_-_43015383 5.02 ENSDART00000065097
dihydropyrimidinase-like 3
chr7_-_60831082 4.92 ENSDART00000073654
ENSDART00000136999
pyruvate carboxylase b
chr7_+_39401388 4.91 ENSDART00000144750
troponin I type 2b (skeletal, fast), tandem duplicate 1
chr25_+_37366698 4.86 ENSDART00000165400
ENSDART00000192589
solute carrier family 1 (glial high affinity glutamate transporter), member 2b
chr20_-_40370736 4.75 ENSDART00000041229
fatty acid binding protein 7, brain, b
chr7_+_44713135 4.70 ENSDART00000170721
si:dkey-56m19.5
chr14_-_25577094 4.63 ENSDART00000163669
complexin 2
chr4_-_16406737 4.57 ENSDART00000013085
decorin
chr11_-_11518469 4.55 ENSDART00000104254
keratin 15
chr8_+_28527776 4.52 ENSDART00000053782
scratch family zinc finger 2
chr11_-_32723851 4.50 ENSDART00000155592
protocadherin 17
chr7_-_58098814 4.40 ENSDART00000147287
ENSDART00000043984
ankyrin 2b, neuronal
chr10_+_31244619 4.30 ENSDART00000145562
ENSDART00000184412
roundabout, axon guidance receptor, homolog 4 (Drosophila)
chr14_-_39074539 4.26 ENSDART00000030509
glycine receptor, alpha 4a
chr12_-_16764751 4.24 ENSDART00000113862
zgc:174154
chr3_-_46811611 4.23 ENSDART00000134092
ELAV like neuron-specific RNA binding protein 3
chr17_+_26569601 4.21 ENSDART00000153897
neuron-derived neurotrophic factor , like
chr20_+_15015557 4.16 ENSDART00000039345
myocilin
chr1_-_38709551 4.15 ENSDART00000128794
glycoprotein M6Ab
chr14_-_1990290 4.14 ENSDART00000183382
protocadherin 2 gamma 5
chr3_+_27027781 4.07 ENSDART00000065495
epithelial membrane protein 2
chr8_+_6954984 4.02 ENSDART00000145610
si:ch211-255g12.6
chr17_-_44247707 3.96 ENSDART00000126097
orthodenticle homeobox 2b
chr23_-_35756115 3.95 ENSDART00000043429
junctophilin 2
chr4_-_12862087 3.93 ENSDART00000080536
high mobility group AT-hook 2
chr16_+_23431189 3.93 ENSDART00000004679
ictacalcin
chr10_+_22724059 3.91 ENSDART00000136123
lysine (K)-specific demethylase 6B, b
chr12_+_32388860 3.69 ENSDART00000075568
noggin 3
chr6_-_20875111 3.65 ENSDART00000115118
ENSDART00000159916
tensin 1a
chr5_+_9348284 3.64 ENSDART00000149417
T-cell acute lymphocytic leukemia 2
chr18_-_45736 3.63 ENSDART00000148373
ENSDART00000148950
glycine amidinotransferase (L-arginine:glycine amidinotransferase)
chr11_+_36989696 3.63 ENSDART00000045888
transketolase a
chr5_-_14344647 3.57 ENSDART00000188456
tet methylcytosine dioxygenase 3
chr14_+_34486629 3.55 ENSDART00000131861
thymosin beta 2
chr1_+_37391141 3.52 ENSDART00000083593
ENSDART00000168647
SPARC-like 1
chr13_-_31435137 3.44 ENSDART00000057441
reticulon 1a
chr1_+_45351890 3.44 ENSDART00000145486
si:ch211-243a20.3
chr18_-_46010 3.42 ENSDART00000052641
glycine amidinotransferase (L-arginine:glycine amidinotransferase)
chr18_-_44610992 3.39 ENSDART00000125968
ENSDART00000185836
sprouty-related, EVH1 domain containing 3
chr19_+_3001473 3.39 ENSDART00000145363
scleraxis bHLH transcription factor a
chr17_+_52822422 3.37 ENSDART00000158273
ENSDART00000161414
Meis homeobox 2a
chr13_+_23214100 3.34 ENSDART00000163393
sorbin and SH3 domain containing 1
chr24_-_4973765 3.32 ENSDART00000127597
zic family member 1 (odd-paired homolog, Drosophila)
chr18_-_39583601 3.32 ENSDART00000125116
tumor necrosis factor, alpha-induced protein 8-like 3
chr8_+_46217861 3.26 ENSDART00000038790
angiopoietin-like 7
chr3_-_38692920 3.23 ENSDART00000155042
membrane protein, palmitoylated 3a (MAGUK p55 subfamily member 3)
chr19_-_1961024 3.22 ENSDART00000108784
maturin, neural progenitor differentiation regulator homolog (Xenopus)
chr10_-_27197044 3.22 ENSDART00000137928
autism susceptibility candidate 2a
chr13_+_41022502 3.18 ENSDART00000026808
dickkopf WNT signaling pathway inhibitor 1a
chr3_+_23687909 3.17 ENSDART00000046638
homeobox B8a
chr16_-_36798783 3.15 ENSDART00000145697
calbindin 1
chr3_-_28075756 3.14 ENSDART00000122037
RNA binding fox-1 homolog 1
chr22_+_38159823 3.08 ENSDART00000104527
transmembrane 4 L six family member 18
chr19_+_4912817 3.07 ENSDART00000101658
ENSDART00000165082
protein phosphatase 1, regulatory (inhibitor) subunit 1B
chr11_-_97817 3.04 ENSDART00000092903
engulfment and cell motility 2
chr12_-_31009315 3.03 ENSDART00000133854
transcription factor 7 like 2
chr2_-_9646857 3.01 ENSDART00000056901
zgc:153615
chr23_+_21459263 2.97 ENSDART00000104209
hairy-related 4, tandem duplicate 3
chr8_+_22931427 2.95 ENSDART00000063096
synaptophysin a
chr5_+_38263240 2.92 ENSDART00000051231
guanine nucleotide binding protein (G protein), beta polypeptide 2
chr15_+_47903864 2.91 ENSDART00000063835
orthodenticle homolog 5
chr3_+_23726148 2.91 ENSDART00000174580
homeobox B3a
chr4_+_2619132 2.89 ENSDART00000128807
G protein-coupled receptor 22a
chr14_-_30642819 2.88 ENSDART00000078154
neuronal PAS domain protein 4a
chr12_-_16941319 2.86 ENSDART00000109968
zgc:174855
chr3_-_39152478 2.83 ENSDART00000154550
si:dkeyp-57f11.2
chr19_-_2231146 2.83 ENSDART00000181909
ENSDART00000043595
twist family bHLH transcription factor 1a
chr18_+_44649804 2.81 ENSDART00000059063
EH-domain containing 2b
chr19_+_30633453 2.79 ENSDART00000052124
family with sequence similarity 49, member A-like
chr9_+_13999620 2.75 ENSDART00000143229
cd28-like molecule
chr6_-_11780070 2.75 ENSDART00000151195
membrane-associated ring finger (C3HC4) 7
chr25_-_11088839 2.75 ENSDART00000154748
synaptic vesicle glycoprotein 2Bb
chr25_+_1732838 2.75 ENSDART00000159555
ENSDART00000168161
fibulin 1
chr14_+_34547554 2.74 ENSDART00000074819
gamma-aminobutyric acid (GABA) A receptor, pi
chr6_+_22597362 2.70 ENSDART00000131242
cytoglobin 2
chr5_-_28625515 2.70 ENSDART00000190782
ENSDART00000179736
ENSDART00000131729
tenascin C
chr12_-_26851726 2.70 ENSDART00000047724
zinc finger E-box binding homeobox 1b
chr12_-_10705916 2.70 ENSDART00000164038

chr1_-_25936677 2.68 ENSDART00000146488
ENSDART00000136321
myozenin 2b
chr18_-_50152689 2.68 ENSDART00000006078
lysyl oxidase-like 1
chr21_+_5169154 2.67 ENSDART00000102559
zgc:122979
chr7_+_26029672 2.65 ENSDART00000101126
arachidonate 12-lipoxygenase
chr15_+_1397811 2.65 ENSDART00000102125
schwannomin interacting protein 1
chr10_-_22803740 2.64 ENSDART00000079469
ENSDART00000187968
ENSDART00000122543
procollagen C-endopeptidase enhancer a
chr4_-_17055782 2.64 ENSDART00000134595
SRY (sex determining region Y)-box 5
chr24_+_41931585 2.63 ENSDART00000130310
erythrocyte membrane protein band 4.1-like 3a
chr16_-_23800484 2.62 ENSDART00000139964
ribosomal protein S27, isoform 2
chr4_+_12612145 2.62 ENSDART00000181201
LIM domain only 3
chr10_-_35542071 2.62 ENSDART00000162139
si:ch211-244c8.4
chr18_+_21122818 2.59 ENSDART00000060015
ENSDART00000060184
choline kinase alpha
chr13_-_45523026 2.59 ENSDART00000020663
Rh blood group, D antigen
chr23_-_31428763 2.52 ENSDART00000053545
zgc:153284
chr10_+_10210455 2.52 ENSDART00000144214
SH2 domain containing 3Ca
chr9_+_14152211 2.52 ENSDART00000148055
si:ch211-67e16.11
chr15_-_2188332 2.51 ENSDART00000138941
ENSDART00000009564
short stature homeobox 2
chr20_+_15982482 2.51 ENSDART00000020999
angiopoietin-like 1a
chr25_-_12788370 2.49 ENSDART00000158551
solute carrier family 7 (amino acid transporter light chain, L system), member 5
chr14_+_24283915 2.47 ENSDART00000172868
kelch-like family member 3
chr13_+_28854438 2.46 ENSDART00000193407
ENSDART00000189554

chr11_-_3334248 2.45 ENSDART00000154314
ENSDART00000121861
peripherin
chr2_+_22694382 2.45 ENSDART00000139196
kinesin family member 1Ab
chr20_+_20672163 2.41 ENSDART00000027758
reticulon 1b
chr4_-_17055950 2.39 ENSDART00000162945
SRY (sex determining region Y)-box 5
chr11_-_44543082 2.39 ENSDART00000099568
G protein-coupled receptor 137Bb
chr3_+_60721342 2.39 ENSDART00000157772
forkhead box J1a
chr7_+_46261199 2.38 ENSDART00000170390
ENSDART00000183227
zinc finger protein 536
chr3_-_22212764 2.37 ENSDART00000155490
microtubule-associated protein tau b
chr1_-_29045426 2.36 ENSDART00000019770
glycoprotein M6Ba
chr15_+_47440477 2.35 ENSDART00000002384
paired-like homeobox 2a
chr9_-_14108896 2.35 ENSDART00000135209
protein kinase, AMP-activated, gamma 3b non-catalytic subunit
chr1_-_22861348 2.35 ENSDART00000139412
si:dkey-92j12.6
chr11_-_21304452 2.34 ENSDART00000163008
si:dkey-85p17.3
chr16_+_7662609 2.29 ENSDART00000184895
ENSDART00000149404
ENSDART00000081418
ENSDART00000081422
blood vessel epicardial substance
chr3_-_28120092 2.28 ENSDART00000151143
RNA binding fox-1 homolog 1
chr16_-_21785261 2.28 ENSDART00000078858
si:ch73-86n18.1
chr4_+_20255160 2.27 ENSDART00000188658
leucine-rich repeats and transmembrane domains 2a
chr14_-_2602445 2.26 ENSDART00000166910
eukaryotic translation termination factor 1a
chr25_+_31323978 2.24 ENSDART00000067030
lymphocyte-specific protein 1
chr16_-_26296477 2.23 ENSDART00000157553
Ets2 repressor factor like 1
chr16_+_24842662 2.22 ENSDART00000157333
si:dkey-79d12.6
chr7_+_44445595 2.21 ENSDART00000108766
cadherin 5
chr15_-_3736773 2.20 ENSDART00000090624
lysophosphatidic acid receptor 6a
chr13_+_22480496 2.20 ENSDART00000136863
ENSDART00000131870
ENSDART00000078720
ENSDART00000078740
ENSDART00000139218
LIM domain binding 3a
chr4_+_19534833 2.18 ENSDART00000140028
leucine rich repeat containing 4.1
chr2_-_32555625 2.16 ENSDART00000056641
ENSDART00000137531
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 3a
chr22_+_10090673 2.15 ENSDART00000186680
si:dkey-102c8.3
chr3_+_16265924 2.15 ENSDART00000122519
ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 6
chr14_+_30730749 2.15 ENSDART00000087884
coiled-coil domain containing 85B
chr15_-_23342752 2.14 ENSDART00000020425
melanoma cell adhesion molecule b
chr1_+_44127292 2.14 ENSDART00000160542
calcium binding protein 2a
chr3_-_28250722 2.12 ENSDART00000165936
RNA binding fox-1 homolog 1
chr4_-_6459863 2.11 ENSDART00000138367
forkhead box P2
chr3_-_30625219 2.10 ENSDART00000151698
synaptotagmin III
chr21_-_28901095 2.10 ENSDART00000180820
CXXC finger protein 5a
chr11_-_11471857 2.09 ENSDART00000030103
keratin 94
chr2_+_43469241 2.07 ENSDART00000142078
ENSDART00000098265
neuropilin 1b
chr2_-_43168292 2.07 ENSDART00000132588
cAMP responsive element modulator a
chr4_-_1360495 2.06 ENSDART00000164623
pleiotrophin
chr21_-_21373242 2.05 ENSDART00000079629
protein phosphatase, Mg2+/Mn2+ dependent, 1Nb (putative)
chr5_-_67878064 2.02 ENSDART00000111203
transgelin 3a
chr21_+_19648814 2.01 ENSDART00000048581
fibroblast growth factor 10a
chr19_-_26863626 2.00 ENSDART00000145568
proline-rich transmembrane protein 1
chr19_+_9533008 1.99 ENSDART00000104607
family with sequence similarity 131, member Ba
chr2_-_56095275 1.98 ENSDART00000154701
si:ch211-178n15.1
chr21_-_9991502 1.97 ENSDART00000169320
endothelial cell-specific molecule 1
chr6_+_55365632 1.97 ENSDART00000169240
phospholipid transfer protein
chr23_+_14217508 1.96 ENSDART00000143618
baculoviral IAP repeat containing 7
chr20_+_37661229 1.95 ENSDART00000138539
androgen-induced 1 (H. sapiens)
chr19_-_5125663 1.95 ENSDART00000005547
ENSDART00000132642
guanine nucleotide binding protein (G protein), beta polypeptide 3b
chr16_-_16590780 1.95 ENSDART00000059841
si:ch211-257p13.3
chr15_+_19838458 1.95 ENSDART00000101204
activated leukocyte cell adhesion molecule b
chr7_+_19495379 1.93 ENSDART00000180514
si:ch211-212k18.8
chr19_-_27777228 1.93 ENSDART00000046166
adenylate cyclase 2b (brain)
chr18_+_6054816 1.91 ENSDART00000113668
si:ch73-386h18.1
chr2_-_50372467 1.90 ENSDART00000108900
contactin associated protein like 2b
chr4_+_11311315 1.89 ENSDART00000051792
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3Aa
chr1_+_51721851 1.89 ENSDART00000040397
peroxiredoxin 2
chr12_-_34459601 1.89 ENSDART00000111717
fascin actin-bundling protein 2b, retinal
chr25_+_25464630 1.88 ENSDART00000150537
Ras association (RalGDS/AF-6) domain family (N-terminal) member 7a
chr20_+_37661547 1.87 ENSDART00000007253
androgen-induced 1 (H. sapiens)
chr10_-_26729930 1.87 ENSDART00000145532
fibroblast growth factor 13b
chr9_+_21407987 1.86 ENSDART00000145627
gap junction protein, alpha 3
chr20_+_33875256 1.86 ENSDART00000002554
retinoid X receptor, gamma b
chr21_+_45841731 1.85 ENSDART00000038657
fatty acid hydroxylase domain containing 2
chr6_-_39275793 1.85 ENSDART00000180477
ENSDART00000148531
Rho guanine nucleotide exchange factor (GEF) 25b
chr17_-_29902187 1.83 ENSDART00000009104
estrogen-related receptor beta
chr7_-_41468942 1.81 ENSDART00000174087
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 3b
chr19_-_41213718 1.80 ENSDART00000077121
pyruvate dehydrogenase kinase, isozyme 4
chr15_-_33527631 1.80 ENSDART00000187646
ENSDART00000161151
StAR-related lipid transfer (START) domain containing 13b
chr4_+_14360372 1.80 ENSDART00000007103
NUAK family, SNF1-like kinase, 1a
chr3_-_36115339 1.79 ENSDART00000187406
ENSDART00000123505
ENSDART00000151775
RAB11 family interacting protein 4 (class II) a
chr13_+_22480857 1.79 ENSDART00000078721
ENSDART00000044719
ENSDART00000130957
ENSDART00000078757
ENSDART00000130424
ENSDART00000078747
LIM domain binding 3a
chr11_-_25829712 1.78 ENSDART00000103549
v-ski avian sarcoma viral oncogene homolog b
chr21_-_43117327 1.78 ENSDART00000122352
procollagen-proline, 2-oxoglutarate 4-dioxygenase (proline 4-hydroxylase), alpha polypeptide 2
chr5_-_5831037 1.76 ENSDART00000112856
zmp:0000000846
chr14_+_42172257 1.76 ENSDART00000074362
protocadherin 18b
chr12_-_34887943 1.73 ENSDART00000027379
BRD4 interacting chromatin remodeling complex associated protein like
chr3_-_19899914 1.71 ENSDART00000134969
Rho family GTPase 2
chr3_+_32553714 1.71 ENSDART00000165638
paired box 10
chr19_+_16032383 1.71 ENSDART00000046530
RAB42, member RAS oncogene family a
chr18_+_49225552 1.71 ENSDART00000135026
si:ch211-136a13.1
chr17_-_46457622 1.70 ENSDART00000130215
transmembrane protein 179
chr4_-_9173552 1.70 ENSDART00000042963
carbohydrate (chondroitin 4) sulfotransferase 11
chr18_+_12058403 1.69 ENSDART00000140854
ENSDART00000193632
ENSDART00000190519
ENSDART00000190685
ENSDART00000112671
bicaudal D homolog 1a
chr3_-_33417826 1.68 ENSDART00000084284
ABI family, member 3a
chr10_+_34394454 1.67 ENSDART00000110121
StAR-related lipid transfer (START) domain containing 13a
chr17_-_26926577 1.67 ENSDART00000050202
regulator of calcineurin 3
chr13_-_50139916 1.66 ENSDART00000099475
nidogen 1a
chr3_-_30685401 1.65 ENSDART00000151097
si:ch211-51c14.1

Network of associatons between targets according to the STRING database.

First level regulatory network of maza+mazb

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
2.4 7.1 GO:0006601 creatine metabolic process(GO:0006600) creatine biosynthetic process(GO:0006601)
1.9 5.7 GO:2001014 regulation of skeletal muscle cell differentiation(GO:2001014)
1.7 8.6 GO:0032616 interleukin-13 production(GO:0032616) regulation of interleukin-13 production(GO:0032656)
1.4 4.3 GO:0001954 positive regulation of cell-matrix adhesion(GO:0001954)
1.4 4.1 GO:0003093 renal system process involved in regulation of blood volume(GO:0001977) renal system process involved in regulation of systemic arterial blood pressure(GO:0003071) regulation of glomerular filtration(GO:0003093)
1.2 6.1 GO:0098881 exocytic insertion of neurotransmitter receptor to plasma membrane(GO:0098881) exocytic insertion of neurotransmitter receptor to postsynaptic membrane(GO:0098967)
1.1 3.4 GO:0035992 tendon formation(GO:0035992)
0.9 5.7 GO:0035332 positive regulation of hippo signaling(GO:0035332)
0.9 5.6 GO:0010799 regulation of peptidyl-threonine phosphorylation(GO:0010799) negative regulation of peptidyl-threonine phosphorylation(GO:0010801)
0.9 2.7 GO:0014814 regulation of synaptic growth at neuromuscular junction(GO:0008582) axon regeneration at neuromuscular junction(GO:0014814) positive regulation of synaptic growth at neuromuscular junction(GO:0045887)
0.9 4.4 GO:0036371 protein localization to T-tubule(GO:0036371)
0.8 2.5 GO:1903792 regulation of neurotransmitter uptake(GO:0051580) negative regulation of anion transport(GO:1903792)
0.8 2.5 GO:0072156 distal tubule morphogenesis(GO:0072156)
0.8 2.4 GO:0036378 calcitriol biosynthetic process from calciol(GO:0036378) vitamin D biosynthetic process(GO:0042368) cellular alcohol metabolic process(GO:0044107) cellular alcohol biosynthetic process(GO:0044108)
0.8 2.4 GO:0045671 negative regulation of osteoclast differentiation(GO:0045671)
0.8 3.2 GO:1900271 regulation of presynaptic cytosolic calcium ion concentration(GO:0099509) regulation of long-term synaptic potentiation(GO:1900271)
0.8 3.0 GO:0010226 response to lithium ion(GO:0010226)
0.7 3.0 GO:1990697 protein depalmitoleylation(GO:1990697)
0.7 3.6 GO:0009052 pentose-phosphate shunt, non-oxidative branch(GO:0009052)
0.7 2.1 GO:0070857 regulation of bile acid biosynthetic process(GO:0070857) regulation of bile acid metabolic process(GO:1904251)
0.7 2.0 GO:0034375 high-density lipoprotein particle remodeling(GO:0034375)
0.6 3.2 GO:0030219 megakaryocyte differentiation(GO:0030219)
0.6 2.5 GO:0060437 lung growth(GO:0060437) secretion by lung epithelial cell involved in lung growth(GO:0061033)
0.6 1.9 GO:0048569 post-embryonic organ development(GO:0048569)
0.6 5.4 GO:0032986 nucleosome disassembly(GO:0006337) chromatin disassembly(GO:0031498) protein-DNA complex disassembly(GO:0032986)
0.6 2.9 GO:0060080 inhibitory postsynaptic potential(GO:0060080)
0.6 3.4 GO:0001919 regulation of receptor recycling(GO:0001919)
0.6 4.5 GO:0043516 regulation of DNA damage response, signal transduction by p53 class mediator(GO:0043516)
0.6 2.2 GO:2000114 regulation of establishment of cell polarity(GO:2000114)
0.5 2.7 GO:0070587 regulation of cell-cell adhesion involved in gastrulation(GO:0070587)
0.5 2.1 GO:0035767 endothelial cell chemotaxis(GO:0035767)
0.5 6.2 GO:0050936 xanthophore differentiation(GO:0050936)
0.5 2.4 GO:0060295 regulation of cilium movement involved in cell motility(GO:0060295) regulation of cilium beat frequency involved in ciliary motility(GO:0060296) regulation of cilium-dependent cell motility(GO:1902019)
0.5 3.3 GO:0021534 cell proliferation in hindbrain(GO:0021534)
0.5 2.3 GO:0002184 cytoplasmic translational termination(GO:0002184)
0.4 1.3 GO:0048682 axon extension involved in regeneration(GO:0048677) sprouting of injured axon(GO:0048682)
0.4 2.6 GO:0003272 endocardial cushion morphogenesis(GO:0003203) endocardial cushion formation(GO:0003272)
0.4 5.0 GO:0051491 positive regulation of filopodium assembly(GO:0051491)
0.4 3.9 GO:0071557 histone H3-K27 demethylation(GO:0071557)
0.4 4.3 GO:0060012 synaptic transmission, glycinergic(GO:0060012)
0.4 1.9 GO:0099612 protein localization to juxtaparanode region of axon(GO:0071205) protein localization to axon(GO:0099612)
0.4 1.9 GO:0048755 branching morphogenesis of a nerve(GO:0048755)
0.4 4.1 GO:0051489 regulation of filopodium assembly(GO:0051489)
0.4 3.6 GO:0042989 sequestering of actin monomers(GO:0042989)
0.3 2.6 GO:0072488 ammonium transmembrane transport(GO:0072488)
0.3 1.0 GO:0060292 long term synaptic depression(GO:0060292)
0.3 4.5 GO:0001952 regulation of cell-matrix adhesion(GO:0001952)
0.3 0.9 GO:0014014 negative regulation of gliogenesis(GO:0014014)
0.3 2.9 GO:0071300 cellular response to retinoic acid(GO:0071300)
0.3 2.6 GO:1904861 excitatory synapse assembly(GO:1904861)
0.3 1.4 GO:0033119 negative regulation of RNA splicing(GO:0033119) negative regulation of mRNA splicing, via spliceosome(GO:0048025)
0.3 1.7 GO:0060632 regulation of microtubule-based movement(GO:0060632)
0.3 1.9 GO:0021885 forebrain cell migration(GO:0021885)
0.3 1.4 GO:0016322 neuron remodeling(GO:0016322)
0.3 0.8 GO:0021531 spinal cord radial glial cell differentiation(GO:0021531) eye field cell fate commitment involved in camera-type eye formation(GO:0060898)
0.3 4.9 GO:0046686 response to cadmium ion(GO:0046686)
0.3 1.3 GO:0050868 negative regulation of T cell activation(GO:0050868) negative regulation of leukocyte cell-cell adhesion(GO:1903038)
0.3 1.0 GO:2000742 cytidine to uridine editing(GO:0016554) regulation of anterior head development(GO:2000742)
0.2 1.2 GO:0001886 endothelial cell morphogenesis(GO:0001886)
0.2 1.0 GO:0048014 Tie signaling pathway(GO:0048014)
0.2 1.2 GO:0006691 leukotriene metabolic process(GO:0006691) leukotriene biosynthetic process(GO:0019370)
0.2 4.0 GO:0003406 retinal pigment epithelium development(GO:0003406)
0.2 3.7 GO:0035844 cloaca development(GO:0035844)
0.2 1.4 GO:0010752 regulation of cGMP-mediated signaling(GO:0010752)
0.2 2.6 GO:0051121 lipoxygenase pathway(GO:0019372) linoleic acid metabolic process(GO:0043651) hepoxilin metabolic process(GO:0051121) hepoxilin biosynthetic process(GO:0051122)
0.2 2.3 GO:0021703 locus ceruleus development(GO:0021703)
0.2 4.6 GO:0048791 calcium ion-regulated exocytosis of neurotransmitter(GO:0048791)
0.2 1.9 GO:0000303 response to superoxide(GO:0000303) response to oxygen radical(GO:0000305) removal of superoxide radicals(GO:0019430) cellular response to oxygen radical(GO:0071450) cellular response to superoxide(GO:0071451) cellular oxidant detoxification(GO:0098869) cellular detoxification(GO:1990748)
0.2 1.7 GO:0070571 negative regulation of axon regeneration(GO:0048681) negative regulation of neuron projection regeneration(GO:0070571)
0.2 2.8 GO:0016199 axon midline choice point recognition(GO:0016199)
0.2 6.3 GO:0050654 chondroitin sulfate proteoglycan metabolic process(GO:0050654)
0.2 3.2 GO:0021884 forebrain neuron development(GO:0021884)
0.2 7.5 GO:0021854 hypothalamus development(GO:0021854)
0.2 0.9 GO:0050996 positive regulation of lipid catabolic process(GO:0050996)
0.2 3.2 GO:1990399 sensory epithelium regeneration(GO:0070654) epithelium regeneration(GO:1990399)
0.2 0.7 GO:0055016 hypochord development(GO:0055016)
0.2 3.0 GO:0048936 peripheral nervous system neuron axonogenesis(GO:0048936)
0.2 2.1 GO:0045471 response to ethanol(GO:0045471)
0.2 2.7 GO:0018057 peptidyl-lysine oxidation(GO:0018057)
0.2 1.2 GO:0006703 estrogen biosynthetic process(GO:0006703)
0.2 1.4 GO:0016576 histone dephosphorylation(GO:0016576) negative regulation of signal transduction in absence of ligand(GO:1901099) regulation of extrinsic apoptotic signaling pathway in absence of ligand(GO:2001239) negative regulation of extrinsic apoptotic signaling pathway in absence of ligand(GO:2001240)
0.1 0.6 GO:0038093 Fc receptor signaling pathway(GO:0038093)
0.1 2.5 GO:0045747 positive regulation of Notch signaling pathway(GO:0045747)
0.1 2.7 GO:0015671 oxygen transport(GO:0015671)
0.1 1.9 GO:1905150 regulation of voltage-gated sodium channel activity(GO:1905150)
0.1 3.0 GO:0071910 determination of liver left/right asymmetry(GO:0071910)
0.1 3.6 GO:0021514 ventral spinal cord interneuron differentiation(GO:0021514)
0.1 1.5 GO:0034497 protein localization to pre-autophagosomal structure(GO:0034497)
0.1 3.9 GO:0051085 chaperone mediated protein folding requiring cofactor(GO:0051085)
0.1 1.2 GO:0006189 'de novo' IMP biosynthetic process(GO:0006189)
0.1 4.5 GO:0060219 camera-type eye photoreceptor cell differentiation(GO:0060219)
0.1 2.5 GO:0033138 positive regulation of peptidyl-serine phosphorylation(GO:0033138)
0.1 2.6 GO:0000028 ribosomal small subunit assembly(GO:0000028)
0.1 0.8 GO:0070293 renal absorption(GO:0070293)
0.1 0.5 GO:0031649 heat generation(GO:0031649) regulation of heat generation(GO:0031650) positive regulation of heat generation(GO:0031652) regulation of phospholipid biosynthetic process(GO:0071071) negative regulation of phospholipid biosynthetic process(GO:0071072)
0.1 4.6 GO:0032456 endocytic recycling(GO:0032456)
0.1 1.1 GO:0015804 neutral amino acid transport(GO:0015804)
0.1 2.3 GO:0097320 membrane tubulation(GO:0097320)
0.1 0.4 GO:2001224 positive regulation of neuron migration(GO:2001224)
0.1 3.8 GO:0035025 positive regulation of Rho protein signal transduction(GO:0035025)
0.1 4.9 GO:0003009 skeletal muscle contraction(GO:0003009)
0.1 0.9 GO:0010002 cardioblast differentiation(GO:0010002) negative regulation of muscle organ development(GO:0048635)
0.1 4.0 GO:0051588 regulation of neurotransmitter transport(GO:0051588)
0.1 0.8 GO:0042744 hydrogen peroxide catabolic process(GO:0042744)
0.1 1.5 GO:0046051 UTP biosynthetic process(GO:0006228) UTP metabolic process(GO:0046051)
0.1 1.1 GO:0061077 chaperone-mediated protein folding(GO:0061077)
0.1 0.6 GO:0021627 olfactory nerve development(GO:0021553) olfactory nerve morphogenesis(GO:0021627) olfactory nerve formation(GO:0021628)
0.1 0.9 GO:0006108 malate metabolic process(GO:0006108)
0.1 1.9 GO:0032526 response to retinoic acid(GO:0032526)
0.1 4.8 GO:0003333 amino acid transmembrane transport(GO:0003333)
0.1 2.3 GO:0031103 axon regeneration(GO:0031103)
0.1 2.6 GO:0032482 Rab protein signal transduction(GO:0032482)
0.1 0.7 GO:0051013 microtubule severing(GO:0051013)
0.1 1.6 GO:0019471 peptidyl-proline hydroxylation to 4-hydroxy-L-proline(GO:0018401) 4-hydroxyproline metabolic process(GO:0019471)
0.1 0.7 GO:0097374 sensory neuron axon guidance(GO:0097374)
0.1 0.8 GO:0097369 sodium ion import(GO:0097369) sodium ion import across plasma membrane(GO:0098719) sodium ion import into cell(GO:1990118)
0.1 4.8 GO:0050919 negative chemotaxis(GO:0050919)
0.1 1.1 GO:0051496 positive regulation of stress fiber assembly(GO:0051496)
0.1 2.8 GO:0045103 intermediate filament-based process(GO:0045103) intermediate filament cytoskeleton organization(GO:0045104)
0.1 0.9 GO:0006123 mitochondrial electron transport, cytochrome c to oxygen(GO:0006123)
0.1 0.8 GO:0030520 intracellular estrogen receptor signaling pathway(GO:0030520)
0.1 0.7 GO:0051601 exocyst localization(GO:0051601)
0.1 3.7 GO:0042129 regulation of T cell proliferation(GO:0042129)
0.1 2.8 GO:0060037 pharyngeal system development(GO:0060037)
0.1 0.8 GO:0036368 cone photoresponse recovery(GO:0036368)
0.1 1.3 GO:0000463 maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000463)
0.1 3.8 GO:0035023 regulation of Rho protein signal transduction(GO:0035023)
0.1 2.1 GO:0014059 dopamine secretion(GO:0014046) regulation of dopamine secretion(GO:0014059)
0.1 1.8 GO:0048013 ephrin receptor signaling pathway(GO:0048013)
0.1 4.6 GO:1902476 chloride transmembrane transport(GO:1902476)
0.1 1.5 GO:0070593 dendrite self-avoidance(GO:0070593)
0.1 1.6 GO:0007168 receptor guanylyl cyclase signaling pathway(GO:0007168)
0.1 0.5 GO:0098700 neurotransmitter loading into synaptic vesicle(GO:0098700)
0.1 0.9 GO:0007214 gamma-aminobutyric acid signaling pathway(GO:0007214)
0.1 1.4 GO:0008214 protein demethylation(GO:0006482) protein dealkylation(GO:0008214)
0.1 2.0 GO:0031398 positive regulation of protein ubiquitination(GO:0031398)
0.1 0.2 GO:1901017 negative regulation of potassium ion transmembrane transporter activity(GO:1901017) negative regulation of potassium ion transmembrane transport(GO:1901380) negative regulation of delayed rectifier potassium channel activity(GO:1902260) negative regulation of voltage-gated potassium channel activity(GO:1903817)
0.1 0.5 GO:0048922 posterior lateral line neuromast deposition(GO:0048922)
0.1 0.3 GO:0007157 heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0007157)
0.1 6.5 GO:0002088 lens development in camera-type eye(GO:0002088)
0.0 0.1 GO:0051610 serotonin transport(GO:0006837) serotonin uptake(GO:0051610)
0.0 0.1 GO:2000108 regulation of platelet activation(GO:0010543) regulation of platelet aggregation(GO:0090330) positive regulation of leukocyte apoptotic process(GO:2000108)
0.0 0.3 GO:1902269 polyamine transport(GO:0015846) polyamine transmembrane transport(GO:1902047) regulation of polyamine transmembrane transport(GO:1902267) positive regulation of polyamine transmembrane transport(GO:1902269)
0.0 0.6 GO:0046085 adenosine metabolic process(GO:0046085)
0.0 0.4 GO:0048172 regulation of short-term neuronal synaptic plasticity(GO:0048172)
0.0 1.5 GO:0016339 calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0016339)
0.0 0.9 GO:1901385 regulation of voltage-gated calcium channel activity(GO:1901385)
0.0 1.3 GO:0046785 microtubule polymerization(GO:0046785)
0.0 0.9 GO:0033209 tumor necrosis factor-mediated signaling pathway(GO:0033209)
0.0 1.9 GO:0016126 sterol biosynthetic process(GO:0016126)
0.0 3.2 GO:0006836 neurotransmitter transport(GO:0006836)
0.0 1.1 GO:0005978 glycogen biosynthetic process(GO:0005978) glucan biosynthetic process(GO:0009250)
0.0 1.8 GO:0010906 regulation of glucose metabolic process(GO:0010906)
0.0 1.7 GO:0032922 circadian regulation of gene expression(GO:0032922)
0.0 0.9 GO:0071222 cellular response to molecule of bacterial origin(GO:0071219) cellular response to lipopolysaccharide(GO:0071222)
0.0 7.6 GO:0007156 homophilic cell adhesion via plasma membrane adhesion molecules(GO:0007156)
0.0 1.1 GO:0039020 pronephric nephron tubule development(GO:0039020)
0.0 0.5 GO:0045880 positive regulation of smoothened signaling pathway(GO:0045880)
0.0 4.8 GO:0002040 sprouting angiogenesis(GO:0002040)
0.0 2.1 GO:0051781 positive regulation of cell division(GO:0051781)
0.0 1.8 GO:0030514 negative regulation of BMP signaling pathway(GO:0030514)
0.0 2.3 GO:0009880 embryonic pattern specification(GO:0009880)
0.0 0.2 GO:0006646 phosphatidylethanolamine biosynthetic process(GO:0006646)
0.0 1.2 GO:0042149 cellular response to glucose starvation(GO:0042149)
0.0 1.6 GO:0006911 phagocytosis, engulfment(GO:0006911)
0.0 2.9 GO:0019722 calcium-mediated signaling(GO:0019722)
0.0 0.3 GO:0097324 melanocyte migration(GO:0097324)
0.0 0.3 GO:0060078 regulation of postsynaptic membrane potential(GO:0060078) excitatory postsynaptic potential(GO:0060079) chemical synaptic transmission, postsynaptic(GO:0099565)
0.0 1.1 GO:0006471 protein ADP-ribosylation(GO:0006471)
0.0 0.3 GO:0000710 meiotic mismatch repair(GO:0000710)
0.0 3.1 GO:0048024 regulation of mRNA splicing, via spliceosome(GO:0048024)
0.0 3.3 GO:0007626 locomotory behavior(GO:0007626)
0.0 1.4 GO:0008045 motor neuron axon guidance(GO:0008045)
0.0 1.3 GO:0006909 phagocytosis(GO:0006909)
0.0 0.4 GO:0042407 cristae formation(GO:0042407)
0.0 0.7 GO:0033627 cell adhesion mediated by integrin(GO:0033627)
0.0 0.1 GO:0033690 positive regulation of osteoblast proliferation(GO:0033690)
0.0 1.2 GO:0007193 adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway(GO:0007193)
0.0 1.8 GO:0008016 regulation of heart contraction(GO:0008016)
0.0 5.7 GO:0006869 lipid transport(GO:0006869)
0.0 0.1 GO:0060074 synapse maturation(GO:0060074)
0.0 0.2 GO:0070262 peptidyl-serine dephosphorylation(GO:0070262)
0.0 1.7 GO:0008360 regulation of cell shape(GO:0008360)
0.0 0.4 GO:0060117 auditory receptor cell development(GO:0060117)
0.0 0.5 GO:0050772 positive regulation of axonogenesis(GO:0050772)
0.0 0.7 GO:0006171 cAMP biosynthetic process(GO:0006171)
0.0 0.4 GO:0009948 anterior/posterior axis specification(GO:0009948)
0.0 1.7 GO:0007160 cell-matrix adhesion(GO:0007160)
0.0 0.9 GO:0006730 one-carbon metabolic process(GO:0006730)
0.0 0.1 GO:0019375 galactosylceramide biosynthetic process(GO:0006682) galactolipid biosynthetic process(GO:0019375)
0.0 0.8 GO:0018298 protein-chromophore linkage(GO:0018298)
0.0 0.9 GO:0014065 phosphatidylinositol 3-kinase signaling(GO:0014065)
0.0 0.1 GO:0031102 neuron projection regeneration(GO:0031102)
0.0 2.4 GO:0070588 calcium ion transmembrane transport(GO:0070588)
0.0 0.3 GO:0098884 postsynaptic neurotransmitter receptor internalization(GO:0098884)
0.0 1.3 GO:0051260 protein homooligomerization(GO:0051260)
0.0 0.7 GO:0051017 actin filament bundle assembly(GO:0051017)
0.0 0.6 GO:0045214 sarcomere organization(GO:0045214)
0.0 0.5 GO:0060395 SMAD protein signal transduction(GO:0060395)
0.0 0.2 GO:0043124 negative regulation of I-kappaB kinase/NF-kappaB signaling(GO:0043124)
0.0 0.2 GO:0007271 synaptic transmission, cholinergic(GO:0007271)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.8 4.0 GO:0030314 junctional membrane complex(GO:0030314)
0.8 3.0 GO:0071664 catenin-TCF7L2 complex(GO:0071664)
0.5 2.3 GO:0018444 translation release factor complex(GO:0018444)
0.4 6.6 GO:0071564 npBAF complex(GO:0071564)
0.4 6.5 GO:0031680 G-protein beta/gamma-subunit complex(GO:0031680)
0.4 8.1 GO:0090665 dystrophin-associated glycoprotein complex(GO:0016010) glycoprotein complex(GO:0090665)
0.3 1.4 GO:0043083 synaptic cleft(GO:0043083)
0.3 4.1 GO:0044295 axonal growth cone(GO:0044295)
0.3 7.2 GO:0043195 terminal bouton(GO:0043195)
0.3 4.4 GO:0030315 T-tubule(GO:0030315)
0.3 6.5 GO:0048787 presynaptic active zone membrane(GO:0048787)
0.3 3.2 GO:0031588 nucleotide-activated protein kinase complex(GO:0031588)
0.2 1.2 GO:0042584 chromaffin granule membrane(GO:0042584)
0.2 1.9 GO:0033010 paranodal junction(GO:0033010)
0.2 1.4 GO:0005854 nascent polypeptide-associated complex(GO:0005854)
0.2 3.9 GO:0044666 MLL3/4 complex(GO:0044666)
0.2 2.6 GO:0005922 connexon complex(GO:0005922)
0.2 1.5 GO:0034045 pre-autophagosomal structure membrane(GO:0034045)
0.2 2.6 GO:0005869 dynactin complex(GO:0005869)
0.2 5.4 GO:1902711 GABA receptor complex(GO:1902710) GABA-A receptor complex(GO:1902711)
0.1 2.0 GO:0005751 mitochondrial respiratory chain complex IV(GO:0005751)
0.1 1.9 GO:0097038 perinuclear endoplasmic reticulum(GO:0097038)
0.1 4.3 GO:0034707 chloride channel complex(GO:0034707)
0.1 4.6 GO:0055038 recycling endosome membrane(GO:0055038)
0.1 4.2 GO:0005791 rough endoplasmic reticulum(GO:0005791)
0.1 3.4 GO:0098831 cytoskeleton of presynaptic active zone(GO:0048788) presynaptic active zone cytoplasmic component(GO:0098831)
0.1 4.9 GO:0005861 troponin complex(GO:0005861)
0.1 0.9 GO:0032593 insulin-responsive compartment(GO:0032593)
0.1 3.0 GO:0048786 presynaptic active zone(GO:0048786)
0.1 1.3 GO:1990589 ATF4-CREB1 transcription factor complex(GO:1990589)
0.1 0.8 GO:0032783 ELL-EAF complex(GO:0032783)
0.1 9.8 GO:0005882 intermediate filament(GO:0005882)
0.1 1.1 GO:0005964 phosphorylase kinase complex(GO:0005964)
0.1 4.0 GO:0031941 filamentous actin(GO:0031941)
0.1 1.5 GO:0030057 desmosome(GO:0030057)
0.1 3.7 GO:0016342 catenin complex(GO:0016342)
0.1 0.9 GO:0044224 juxtaparanode region of axon(GO:0044224)
0.1 4.8 GO:0030018 Z disc(GO:0030018)
0.1 1.0 GO:0031209 SCAR complex(GO:0031209)
0.1 5.6 GO:0005604 basement membrane(GO:0005604)
0.1 2.9 GO:0042383 sarcolemma(GO:0042383)
0.1 3.0 GO:0030175 filopodium(GO:0030175)
0.1 2.6 GO:0022627 cytosolic small ribosomal subunit(GO:0022627)
0.1 3.3 GO:0099501 synaptic vesicle membrane(GO:0030672) exocytic vesicle membrane(GO:0099501)
0.1 1.1 GO:0071144 SMAD2-SMAD3 protein complex(GO:0071144)
0.1 11.8 GO:0030424 axon(GO:0030424)
0.0 3.1 GO:0045121 membrane raft(GO:0045121) membrane microdomain(GO:0098857)
0.0 1.8 GO:0034705 voltage-gated potassium channel complex(GO:0008076) potassium channel complex(GO:0034705)
0.0 0.4 GO:0032591 dendritic spine membrane(GO:0032591)
0.0 0.4 GO:0061617 MICOS complex(GO:0061617)
0.0 1.8 GO:0005788 endoplasmic reticulum lumen(GO:0005788)
0.0 9.0 GO:0005764 lysosome(GO:0005764)
0.0 1.9 GO:0043025 neuronal cell body(GO:0043025)
0.0 0.9 GO:0030427 site of polarized growth(GO:0030427)
0.0 47.9 GO:0005576 extracellular region(GO:0005576)
0.0 0.7 GO:0000145 exocyst(GO:0000145)
0.0 0.8 GO:0031463 Cul3-RING ubiquitin ligase complex(GO:0031463)
0.0 1.1 GO:0005834 heterotrimeric G-protein complex(GO:0005834)
0.0 0.3 GO:0017146 NMDA selective glutamate receptor complex(GO:0017146)
0.0 1.3 GO:0022626 cytosolic ribosome(GO:0022626)
0.0 0.7 GO:0032587 ruffle membrane(GO:0032587)
0.0 0.8 GO:0072686 mitotic spindle(GO:0072686)
0.0 0.8 GO:0001750 photoreceptor outer segment(GO:0001750)
0.0 0.2 GO:0005892 acetylcholine-gated channel complex(GO:0005892)
0.0 5.5 GO:0005874 microtubule(GO:0005874)
0.0 2.8 GO:0009897 external side of plasma membrane(GO:0009897)
0.0 0.8 GO:0031225 anchored component of membrane(GO:0031225)
0.0 0.7 GO:0008305 integrin complex(GO:0008305)
0.0 0.9 GO:0005942 phosphatidylinositol 3-kinase complex(GO:0005942)
0.0 0.3 GO:0000795 synaptonemal complex(GO:0000795)
0.0 3.6 GO:0005743 mitochondrial inner membrane(GO:0005743)
0.0 1.1 GO:0070382 exocytic vesicle(GO:0070382)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
1.6 4.9 GO:0004736 pyruvate carboxylase activity(GO:0004736)
1.2 8.6 GO:0070579 methylcytosine dioxygenase activity(GO:0070579)
1.1 3.2 GO:0005499 vitamin D binding(GO:0005499)
0.8 2.4 GO:0031073 vitamin D3 25-hydroxylase activity(GO:0030343) cholesterol 26-hydroxylase activity(GO:0031073)
0.8 2.3 GO:1990825 sequence-specific mRNA binding(GO:1990825)
0.7 3.0 GO:1990699 palmitoleyl hydrolase activity(GO:1990699)
0.6 3.2 GO:0039706 co-receptor binding(GO:0039706)
0.6 3.6 GO:0016744 transferase activity, transferring aldehyde or ketonic groups(GO:0016744)
0.5 2.0 GO:1904121 phosphatidylethanolamine transporter activity(GO:1904121)
0.5 4.3 GO:0016934 extracellular-glycine-gated ion channel activity(GO:0016933) extracellular-glycine-gated chloride channel activity(GO:0016934)
0.4 2.1 GO:0055077 gap junction hemi-channel activity(GO:0055077)
0.4 5.0 GO:0004157 dihydropyrimidinase activity(GO:0004157)
0.4 3.9 GO:0071558 histone demethylase activity (H3-K27 specific)(GO:0071558)
0.4 2.7 GO:0098809 nitrite reductase activity(GO:0098809)
0.3 1.7 GO:0034481 chondroitin sulfotransferase activity(GO:0034481)
0.3 4.7 GO:0005504 fatty acid binding(GO:0005504)
0.3 0.9 GO:0005131 growth hormone receptor binding(GO:0005131) growth hormone activity(GO:0070186)
0.3 6.5 GO:0031681 G-protein beta-subunit binding(GO:0031681)
0.3 1.2 GO:0047035 testosterone dehydrogenase (NAD+) activity(GO:0047035)
0.3 4.8 GO:0048495 Roundabout binding(GO:0048495)
0.3 1.2 GO:0004639 phosphoribosylaminoimidazolesuccinocarboxamide synthase activity(GO:0004639)
0.3 2.6 GO:0008273 calcium, potassium:sodium antiporter activity(GO:0008273)
0.3 1.7 GO:0008597 calcium-dependent protein serine/threonine phosphatase regulator activity(GO:0008597)
0.3 1.9 GO:0008379 thioredoxin peroxidase activity(GO:0008379)
0.3 2.1 GO:0003828 alpha-N-acetylneuraminate alpha-2,8-sialyltransferase activity(GO:0003828)
0.3 2.7 GO:0051373 telethonin binding(GO:0031433) FATZ binding(GO:0051373)
0.3 1.9 GO:0000254 C-4 methylsterol oxidase activity(GO:0000254)
0.3 8.6 GO:0098632 protein binding involved in cell-cell adhesion(GO:0098632)
0.2 4.4 GO:0004190 aspartic-type endopeptidase activity(GO:0004190) aspartic-type peptidase activity(GO:0070001)
0.2 1.8 GO:0004740 pyruvate dehydrogenase (acetyl-transferring) kinase activity(GO:0004740)
0.2 0.9 GO:0051916 granulocyte colony-stimulating factor binding(GO:0051916)
0.2 1.1 GO:0004689 phosphorylase kinase activity(GO:0004689)
0.2 0.9 GO:0097108 hedgehog family protein binding(GO:0097108)
0.2 7.1 GO:0016769 transferase activity, transferring nitrogenous groups(GO:0016769)
0.2 8.1 GO:0005518 collagen binding(GO:0005518)
0.2 1.7 GO:0034452 dynactin binding(GO:0034452)
0.2 2.5 GO:0005111 type 2 fibroblast growth factor receptor binding(GO:0005111)
0.2 1.9 GO:0044323 retinoic acid-responsive element binding(GO:0044323)
0.2 4.0 GO:0051371 muscle alpha-actinin binding(GO:0051371) alpha-actinin binding(GO:0051393)
0.2 1.2 GO:0036374 peptidyltransferase activity(GO:0000048) glutathione hydrolase activity(GO:0036374)
0.2 1.0 GO:0070004 cysteine-type exopeptidase activity(GO:0070004)
0.2 7.6 GO:0017075 syntaxin-1 binding(GO:0017075)
0.2 1.1 GO:0051879 Hsp90 protein binding(GO:0051879)
0.2 2.8 GO:0031682 G-protein gamma-subunit binding(GO:0031682)
0.2 0.9 GO:0030060 L-malate dehydrogenase activity(GO:0030060)
0.2 0.7 GO:0033829 O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase activity(GO:0033829)
0.2 5.0 GO:0048306 calcium-dependent protein binding(GO:0048306)
0.2 3.6 GO:0003785 actin monomer binding(GO:0003785)
0.2 1.6 GO:0004865 protein serine/threonine phosphatase inhibitor activity(GO:0004865)
0.2 2.1 GO:0005021 vascular endothelial growth factor-activated receptor activity(GO:0005021)
0.2 2.1 GO:0005007 fibroblast growth factor-activated receptor activity(GO:0005007)
0.2 5.4 GO:0004890 GABA-A receptor activity(GO:0004890)
0.2 3.3 GO:0046875 ephrin receptor binding(GO:0046875)
0.2 2.7 GO:0004720 protein-lysine 6-oxidase activity(GO:0004720)
0.2 2.3 GO:0038191 neuropilin binding(GO:0038191)
0.2 2.0 GO:0043028 cysteine-type endopeptidase inhibitor activity involved in apoptotic process(GO:0043027) cysteine-type endopeptidase regulator activity involved in apoptotic process(GO:0043028)
0.1 2.1 GO:0008327 methyl-CpG binding(GO:0008327)
0.1 1.4 GO:0070700 BMP receptor binding(GO:0070700)
0.1 0.3 GO:0001227 transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001227)
0.1 2.3 GO:0030552 cAMP binding(GO:0030552)
0.1 0.8 GO:1903924 estradiol binding(GO:1903924)
0.1 1.0 GO:0005159 insulin-like growth factor receptor binding(GO:0005159)
0.1 0.5 GO:0001223 transcription coactivator binding(GO:0001223)
0.1 6.5 GO:0005484 SNAP receptor activity(GO:0005484)
0.1 3.2 GO:0016208 AMP binding(GO:0016208)
0.1 1.0 GO:0071933 Arp2/3 complex binding(GO:0071933)
0.1 2.7 GO:0008519 ammonium transmembrane transporter activity(GO:0008519)
0.1 1.0 GO:0004705 JUN kinase activity(GO:0004705) SAP kinase activity(GO:0016909)
0.1 0.5 GO:0008281 sulfonylurea receptor activity(GO:0008281)
0.1 3.9 GO:0051087 chaperone binding(GO:0051087)
0.1 1.9 GO:0017080 sodium channel regulator activity(GO:0017080)
0.1 4.0 GO:0008013 beta-catenin binding(GO:0008013)
0.1 0.5 GO:0005326 neurotransmitter transporter activity(GO:0005326)
0.1 4.9 GO:0017124 SH3 domain binding(GO:0017124)
0.1 1.8 GO:0031267 small GTPase binding(GO:0031267)
0.1 2.5 GO:0015035 protein disulfide oxidoreductase activity(GO:0015035)
0.1 6.3 GO:0008201 heparin binding(GO:0008201)
0.1 1.0 GO:0004656 procollagen-proline 4-dioxygenase activity(GO:0004656)
0.1 6.4 GO:0005212 structural constituent of eye lens(GO:0005212)
0.1 0.5 GO:0031957 very long-chain fatty acid-CoA ligase activity(GO:0031957)
0.1 4.2 GO:0044325 ion channel binding(GO:0044325)
0.1 1.9 GO:0015248 sterol transporter activity(GO:0015248)
0.1 0.8 GO:0022821 potassium ion antiporter activity(GO:0022821)
0.1 0.2 GO:0050649 testosterone 6-beta-hydroxylase activity(GO:0050649)
0.1 1.0 GO:0070915 lysophosphatidic acid receptor activity(GO:0070915)
0.1 3.3 GO:0001786 phosphatidylserine binding(GO:0001786)
0.1 2.0 GO:0016676 cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors(GO:0016675) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676)
0.1 0.2 GO:0042165 neurotransmitter binding(GO:0042165) acetylcholine binding(GO:0042166)
0.1 1.8 GO:0004016 adenylate cyclase activity(GO:0004016)
0.1 4.6 GO:0015179 L-amino acid transmembrane transporter activity(GO:0015179)
0.1 1.0 GO:0004983 neuropeptide Y receptor activity(GO:0004983)
0.1 1.1 GO:0070411 I-SMAD binding(GO:0070411)
0.1 1.5 GO:0004550 nucleoside diphosphate kinase activity(GO:0004550)
0.0 1.6 GO:0005540 hyaluronic acid binding(GO:0005540)
0.0 0.2 GO:2001070 starch binding(GO:2001070)
0.0 0.8 GO:0042813 Wnt-activated receptor activity(GO:0042813)
0.0 0.4 GO:0005243 gap junction channel activity(GO:0005243)
0.0 1.2 GO:0005520 insulin-like growth factor binding(GO:0005520)
0.0 0.3 GO:0042978 ornithine decarboxylase activator activity(GO:0042978)
0.0 1.5 GO:0032266 phosphatidylinositol-3-phosphate binding(GO:0032266)
0.0 0.5 GO:0030955 potassium ion binding(GO:0030955) alkali metal ion binding(GO:0031420)
0.0 0.2 GO:0004945 angiotensin type I receptor activity(GO:0001596) angiotensin type II receptor activity(GO:0004945)
0.0 0.7 GO:0033691 sialic acid binding(GO:0033691)
0.0 0.5 GO:0001102 RNA polymerase II activating transcription factor binding(GO:0001102)
0.0 0.9 GO:0051018 protein kinase A binding(GO:0051018)
0.0 1.0 GO:0030971 receptor tyrosine kinase binding(GO:0030971)
0.0 1.4 GO:0032452 histone demethylase activity(GO:0032452)
0.0 0.9 GO:0004089 carbonate dehydratase activity(GO:0004089)
0.0 1.3 GO:0015171 amino acid transmembrane transporter activity(GO:0015171)
0.0 3.7 GO:0003777 microtubule motor activity(GO:0003777)
0.0 5.2 GO:0001228 transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001228)
0.0 0.2 GO:0060182 apelin receptor activity(GO:0060182)
0.0 0.9 GO:0008331 high voltage-gated calcium channel activity(GO:0008331)
0.0 0.6 GO:0008253 5'-nucleotidase activity(GO:0008253)
0.0 0.9 GO:0046935 1-phosphatidylinositol-3-kinase regulator activity(GO:0046935)
0.0 0.7 GO:0005388 calcium-transporting ATPase activity(GO:0005388)
0.0 0.5 GO:0000828 inositol hexakisphosphate kinase activity(GO:0000828)
0.0 0.8 GO:0004698 protein kinase C activity(GO:0004697) calcium-dependent protein kinase C activity(GO:0004698)
0.0 0.4 GO:0030506 ankyrin binding(GO:0030506)
0.0 25.8 GO:0005509 calcium ion binding(GO:0005509)
0.0 0.9 GO:0005164 tumor necrosis factor receptor binding(GO:0005164)
0.0 1.0 GO:0004180 carboxypeptidase activity(GO:0004180)
0.0 1.2 GO:0005200 structural constituent of cytoskeleton(GO:0005200)
0.0 0.4 GO:0005005 transmembrane-ephrin receptor activity(GO:0005005)
0.0 0.8 GO:0003707 steroid hormone receptor activity(GO:0003707)
0.0 2.0 GO:0003678 DNA helicase activity(GO:0003678)
0.0 1.6 GO:0051427 hormone receptor binding(GO:0051427)
0.0 0.5 GO:0001540 beta-amyloid binding(GO:0001540)
0.0 1.1 GO:0003950 NAD+ ADP-ribosyltransferase activity(GO:0003950)
0.0 0.7 GO:0005178 integrin binding(GO:0005178)
0.0 11.5 GO:0005198 structural molecule activity(GO:0005198)
0.0 0.3 GO:0002039 p53 binding(GO:0002039)
0.0 10.7 GO:0046983 protein dimerization activity(GO:0046983)
0.0 1.4 GO:0051082 unfolded protein binding(GO:0051082)
0.0 3.2 GO:0015293 symporter activity(GO:0015293)
0.0 0.8 GO:0004601 peroxidase activity(GO:0004601)
0.0 0.1 GO:0004118 cGMP-stimulated cyclic-nucleotide phosphodiesterase activity(GO:0004118)
0.0 0.3 GO:0030983 mismatched DNA binding(GO:0030983)
0.0 24.4 GO:0000978 RNA polymerase II core promoter proximal region sequence-specific DNA binding(GO:0000978)
0.0 0.3 GO:0004972 NMDA glutamate receptor activity(GO:0004972)
0.0 0.8 GO:0008020 G-protein coupled photoreceptor activity(GO:0008020)
0.0 1.9 GO:0005249 voltage-gated potassium channel activity(GO:0005249)
0.0 0.1 GO:0001733 galactosylceramide sulfotransferase activity(GO:0001733) galactose 3-O-sulfotransferase activity(GO:0050694)
0.0 0.2 GO:0045159 myosin II binding(GO:0045159)
0.0 0.1 GO:0030368 interleukin-17 receptor activity(GO:0030368)
0.0 1.9 GO:0042277 peptide binding(GO:0042277)
0.0 0.1 GO:0022850 serotonin-gated cation channel activity(GO:0022850)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 6.3 NABA PROTEOGLYCANS Genes encoding proteoglycans
0.2 2.2 PID P38 MK2 PATHWAY p38 signaling mediated by MAPKAP kinases
0.1 2.7 PID SYNDECAN 4 PATHWAY Syndecan-4-mediated signaling events
0.1 1.0 SA MMP CYTOKINE CONNECTION Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix.
0.1 1.6 PID A6B1 A6B4 INTEGRIN PATHWAY a6b1 and a6b4 Integrin signaling
0.1 1.1 PID IL8 CXCR1 PATHWAY IL8- and CXCR1-mediated signaling events
0.1 0.5 SA PTEN PATHWAY PTEN is a tumor suppressor that dephosphorylates the lipid messenger phosphatidylinositol triphosphate.
0.1 1.0 PID NEPHRIN NEPH1 PATHWAY Nephrin/Neph1 signaling in the kidney podocyte
0.1 3.1 PID CD8 TCR PATHWAY TCR signaling in naïve CD8+ T cells
0.1 2.7 PID ILK PATHWAY Integrin-linked kinase signaling
0.1 2.6 SIG INSULIN RECEPTOR PATHWAY IN CARDIAC MYOCYTES Genes related to the insulin receptor pathway
0.1 1.0 PID CONE PATHWAY Visual signal transduction: Cones
0.1 1.0 PID RAS PATHWAY Regulation of Ras family activation
0.1 0.7 PID INTEGRIN5 PATHWAY Beta5 beta6 beta7 and beta8 integrin cell surface interactions
0.1 4.8 NABA ECM AFFILIATED Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.1 0.9 PID HEDGEHOG 2PATHWAY Signaling events mediated by the Hedgehog family
0.0 7.1 NABA ECM GLYCOPROTEINS Genes encoding structural ECM glycoproteins
0.0 0.1 PID GLYPICAN 1PATHWAY Glypican 1 network
0.0 6.3 NABA SECRETED FACTORS Genes encoding secreted soluble factors
0.0 1.0 PID AP1 PATHWAY AP-1 transcription factor network
0.0 0.6 PID REG GR PATHWAY Glucocorticoid receptor regulatory network
0.0 0.1 PID S1P S1P2 PATHWAY S1P2 pathway

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 9.5 REACTOME INHIBITION OF INSULIN SECRETION BY ADRENALINE NORADRENALINE Genes involved in Inhibition of Insulin Secretion by Adrenaline/Noradrenaline
0.5 5.0 REACTOME CRMPS IN SEMA3A SIGNALING Genes involved in CRMPs in Sema3A signaling
0.4 5.5 REACTOME CHONDROITIN SULFATE BIOSYNTHESIS Genes involved in Chondroitin sulfate biosynthesis
0.4 1.5 REACTOME DSCAM INTERACTIONS Genes involved in DSCAM interactions
0.4 6.1 REACTOME PROTEOLYTIC CLEAVAGE OF SNARE COMPLEX PROTEINS Genes involved in Proteolytic cleavage of SNARE complex proteins
0.3 1.2 REACTOME GLUTAMATE NEUROTRANSMITTER RELEASE CYCLE Genes involved in Glutamate Neurotransmitter Release Cycle
0.3 2.1 REACTOME FGFR4 LIGAND BINDING AND ACTIVATION Genes involved in FGFR4 ligand binding and activation
0.2 1.9 REACTOME GAP JUNCTION TRAFFICKING Genes involved in Gap junction trafficking
0.2 2.6 REACTOME SYNTHESIS OF PE Genes involved in Synthesis of PE
0.2 1.3 REACTOME PHOSPHORYLATION OF CD3 AND TCR ZETA CHAINS Genes involved in Phosphorylation of CD3 and TCR zeta chains
0.2 3.8 REACTOME AMINO ACID TRANSPORT ACROSS THE PLASMA MEMBRANE Genes involved in Amino acid transport across the plasma membrane
0.2 3.3 REACTOME SMOOTH MUSCLE CONTRACTION Genes involved in Smooth Muscle Contraction
0.1 1.8 REACTOME REGULATION OF PYRUVATE DEHYDROGENASE PDH COMPLEX Genes involved in Regulation of pyruvate dehydrogenase (PDH) complex
0.1 1.0 REACTOME ACTIVATION OF THE AP1 FAMILY OF TRANSCRIPTION FACTORS Genes involved in Activation of the AP-1 family of transcription factors
0.1 1.5 REACTOME GABA A RECEPTOR ACTIVATION Genes involved in GABA A receptor activation
0.1 1.5 REACTOME DARPP 32 EVENTS Genes involved in DARPP-32 events
0.1 1.2 REACTOME PURINE RIBONUCLEOSIDE MONOPHOSPHATE BIOSYNTHESIS Genes involved in Purine ribonucleoside monophosphate biosynthesis
0.1 2.0 REACTOME ACTIVATED NOTCH1 TRANSMITS SIGNAL TO THE NUCLEUS Genes involved in Activated NOTCH1 Transmits Signal to the Nucleus
0.1 0.9 REACTOME SYNTHESIS SECRETION AND DEACYLATION OF GHRELIN Genes involved in Synthesis, Secretion, and Deacylation of Ghrelin
0.1 1.2 REACTOME POST CHAPERONIN TUBULIN FOLDING PATHWAY Genes involved in Post-chaperonin tubulin folding pathway
0.0 0.9 REACTOME CITRIC ACID CYCLE TCA CYCLE Genes involved in Citric acid cycle (TCA cycle)
0.0 2.0 REACTOME TRANSPORT OF INORGANIC CATIONS ANIONS AND AMINO ACIDS OLIGOPEPTIDES Genes involved in Transport of inorganic cations/anions and amino acids/oligopeptides
0.0 7.1 REACTOME METABOLISM OF AMINO ACIDS AND DERIVATIVES Genes involved in Metabolism of amino acids and derivatives
0.0 0.7 REACTOME PRE NOTCH PROCESSING IN GOLGI Genes involved in Pre-NOTCH Processing in Golgi
0.0 1.3 REACTOME NCAM1 INTERACTIONS Genes involved in NCAM1 interactions
0.0 0.4 REACTOME INWARDLY RECTIFYING K CHANNELS Genes involved in Inwardly rectifying K+ channels
0.0 0.2 REACTOME LIGAND GATED ION CHANNEL TRANSPORT Genes involved in Ligand-gated ion channel transport
0.0 0.6 REACTOME COLLAGEN FORMATION Genes involved in Collagen formation
0.0 0.9 REACTOME CLASS B 2 SECRETIN FAMILY RECEPTORS Genes involved in Class B/2 (Secretin family receptors)
0.0 0.3 REACTOME METABOLISM OF PORPHYRINS Genes involved in Metabolism of porphyrins
0.0 0.8 REACTOME ASSOCIATION OF TRIC CCT WITH TARGET PROTEINS DURING BIOSYNTHESIS Genes involved in Association of TriC/CCT with target proteins during biosynthesis
0.0 0.8 REACTOME NUCLEAR RECEPTOR TRANSCRIPTION PATHWAY Genes involved in Nuclear Receptor transcription pathway
0.0 0.4 REACTOME MUSCLE CONTRACTION Genes involved in Muscle contraction
0.0 0.2 REACTOME HDL MEDIATED LIPID TRANSPORT Genes involved in HDL-mediated lipid transport
0.0 0.5 REACTOME G1 PHASE Genes involved in G1 Phase
0.0 0.3 REACTOME ADHERENS JUNCTIONS INTERACTIONS Genes involved in Adherens junctions interactions
0.0 0.5 REACTOME ACTIVATION OF CHAPERONE GENES BY XBP1S Genes involved in Activation of Chaperone Genes by XBP1(S)
0.0 1.3 REACTOME PEPTIDE CHAIN ELONGATION Genes involved in Peptide chain elongation
0.0 0.1 REACTOME HIGHLY CALCIUM PERMEABLE POSTSYNAPTIC NICOTINIC ACETYLCHOLINE RECEPTORS Genes involved in Highly calcium permeable postsynaptic nicotinic acetylcholine receptors