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PRJNA195909:zebrafish embryo and larva development

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Results for maff+mafga+mafgb

Z-value: 1.02

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Transcription factors associated with maff+mafga+mafgb

Gene Symbol Gene ID Gene Info
ENSDARG00000018109 v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog Ga
ENSDARG00000028957 v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F
ENSDARG00000100097 v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog Gb
ENSDARG00000111050 v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
mafgadr11_v1_chr3_-_55404985_554049850.561.2e-01Click!
mafgbdr11_v1_chr11_+_45299447_452994470.157.1e-01Click!
maffdr11_v1_chr12_-_19346678_19346678-0.029.6e-01Click!

Activity profile of maff+mafga+mafgb motif

Sorted Z-values of maff+mafga+mafgb motif

Promoter Log-likelihood Transcript Gene Gene Info
chr3_+_32526799 3.33 ENSDART00000185755
si:ch73-367p23.2
chr3_-_55139127 1.98 ENSDART00000115324
hemoglobin, alpha embryonic 1.3
chr3_-_55128258 1.17 ENSDART00000101734
hemoglobin, alpha embryonic 1
chr11_+_30729745 1.17 ENSDART00000103270
solute carrier family 22 (organic anion transporter), member 7a
chr3_+_33300522 0.91 ENSDART00000114023
heat shock protein, alpha-crystallin-related, 9
chr13_+_24280380 0.89 ENSDART00000184115
actin, alpha 1b, skeletal muscle
chr3_-_41795917 0.84 ENSDART00000182662
galectin-related inter-fiber protein
chr18_+_808911 0.83 ENSDART00000172518
cytochrome c oxidase subunit Vab
chr23_-_28347039 0.83 ENSDART00000145072
neuronal differentiation 4
chr2_-_36040820 0.79 ENSDART00000003550
nicotinamide nucleotide adenylyltransferase 2
chr19_-_19339285 0.74 ENSDART00000158413
ENSDART00000170479
chondroitin sulfate proteoglycan 5b
chr21_-_45613564 0.71 ENSDART00000160324

chr12_+_20336070 0.70 ENSDART00000066385
zgc:163057
chr21_-_26495700 0.69 ENSDART00000109379
CD248 molecule, endosialin b
chr21_-_10773344 0.67 ENSDART00000063244
gastrin-releasing peptide
chr24_-_32408404 0.66 ENSDART00000144157
si:ch211-56a11.2
chr1_-_10048514 0.66 ENSDART00000125358
ENSDART00000054835
ring finger protein 175
chr7_-_24491614 0.65 ENSDART00000131063
si:dkeyp-75h12.5
chr7_+_8543317 0.62 ENSDART00000114998
jacalin 8
chr20_+_20637866 0.56 ENSDART00000060203
ENSDART00000079079
reticulon 1b
chr12_+_6041575 0.54 ENSDART00000091868
glucose-6-phosphatase a, catalytic subunit, tandem duplicate 2
chr19_+_25649626 0.54 ENSDART00000146947
tachykinin 1
chr3_-_26109322 0.54 ENSDART00000113780
zgc:162612
chr8_-_54304381 0.53 ENSDART00000184177
rhodopsin
chr25_+_13191615 0.53 ENSDART00000168849
si:ch211-147m6.2
chr19_-_1961024 0.53 ENSDART00000108784
maturin, neural progenitor differentiation regulator homolog (Xenopus)
chr4_+_3358383 0.53 ENSDART00000075320
nicotinamide phosphoribosyltransferase a
chr21_-_43606502 0.53 ENSDART00000151030
si:ch73-362m14.4
chr9_-_23922011 0.53 ENSDART00000145734
collagen, type VI, alpha 3
chr7_+_25059845 0.51 ENSDART00000077215
protein phosphatase 2, regulatory subunit B', beta
chr16_+_10777116 0.50 ENSDART00000190902
ATPase Na+/K+ transporting subunit alpha 3b
chr3_+_31933893 0.50 ENSDART00000146509
ENSDART00000139644
lin-7 homolog B (C. elegans)
chr16_-_12173554 0.49 ENSDART00000110567
ENSDART00000155935
calsyntenin 3
chr24_+_9744012 0.47 ENSDART00000129656
transmembrane protein 108
chr8_-_31075015 0.46 ENSDART00000010993
solute carrier family 20, member 1a
chr6_+_27667359 0.45 ENSDART00000159624
ENSDART00000049177
RAB6B, member RAS oncogene family a
chr21_+_27416284 0.44 ENSDART00000077593
ENSDART00000108763
complement factor B
chr10_-_26512742 0.44 ENSDART00000135951
si:dkey-5g14.1
chr23_-_27345425 0.44 ENSDART00000022042
ENSDART00000191870
sodium channel, voltage gated, type VIII, alpha subunit a
chr17_+_12698532 0.44 ENSDART00000064509
ENSDART00000136830
stathmin-like 4, like
chr8_+_25351863 0.43 ENSDART00000034092
deoxyribonuclease I-like 1-like
chr9_-_4506819 0.43 ENSDART00000113975
potassium inwardly-rectifying channel, subfamily J, member 3a
chr14_-_30490763 0.43 ENSDART00000193166
ENSDART00000183471
ENSDART00000087859
mitochondrial calcium uptake family, member 3b
chr15_-_44512461 0.42 ENSDART00000155456
glutamate receptor, ionotropic, AMPA 4a
chr10_+_21758811 0.42 ENSDART00000188827
protocadherin 1 gamma 11
chr5_-_9073433 0.42 ENSDART00000099891
ATP synthase membrane subunit eb
chr20_+_20638034 0.41 ENSDART00000189759
reticulon 1b
chr12_+_48216662 0.41 ENSDART00000187369
leucine rich repeat containing 20
chr12_-_10300101 0.41 ENSDART00000126428
membrane protein, palmitoylated 2b (MAGUK p55 subfamily member 2)
chr19_+_17385561 0.41 ENSDART00000141397
ENSDART00000143913
ENSDART00000133626
ribosomal protein L15
chr20_-_54259780 0.40 ENSDART00000172631
FK506 binding protein 3
chr7_+_50766094 0.40 ENSDART00000165037
si:ch73-380l10.2
chr10_-_26512993 0.39 ENSDART00000188549
ENSDART00000193316
si:dkey-5g14.1
chr3_-_39171968 0.39 ENSDART00000154494
si:dkeyp-57f11.2
chr17_-_31659670 0.38 ENSDART00000030448
visual system homeobox 2
chr2_-_24996441 0.38 ENSDART00000144795
solute carrier family 35, member G2a
chr21_-_16114061 0.38 ENSDART00000035742
cytochrome b561 family, member A3b
chr23_-_26535875 0.38 ENSDART00000135988
si:dkey-205h13.2
chr5_-_7897316 0.38 ENSDART00000160743
ENSDART00000160912
opsin 4xb
chr10_-_33621739 0.37 ENSDART00000142655
ENSDART00000128049
hormonally up-regulated Neu-associated kinase
chr3_+_15907458 0.37 ENSDART00000163525
mitogen-activated protein kinase 8 interacting protein 3
chr23_-_4915118 0.36 ENSDART00000060714
ATPase H+ transporting accessory protein 1a
chr23_+_216012 0.36 ENSDART00000181115
ENSDART00000004678
ENSDART00000190439
ENSDART00000189322
si:ch73-162j3.4
chr5_-_63509581 0.36 ENSDART00000097325
complement component 5
chr13_+_36146415 0.36 ENSDART00000140301
si:ch211-259k16.3
chr8_+_39607466 0.36 ENSDART00000097427
musashi RNA-binding protein 1
chr6_+_584632 0.36 ENSDART00000151150
zgc:92360
chr7_+_25036188 0.35 ENSDART00000163957
ENSDART00000169749
sb:cb1058
chr19_-_17385548 0.35 ENSDART00000162383
NFKB inhibitor interacting Ras-like 1
chr21_-_41147818 0.35 ENSDART00000167339
ENSDART00000192730
muscle segment homeobox 2b
chr19_+_43563179 0.35 ENSDART00000151478
CD164 sialomucin-like 2
chr14_-_17072736 0.34 ENSDART00000106333
paired-like homeobox 2bb
chr7_+_42206543 0.34 ENSDART00000112543
phosphorylase kinase, beta
chr10_+_20113830 0.33 ENSDART00000139722
dematin actin binding protein
chr16_+_12240605 0.33 ENSDART00000060056
triosephosphate isomerase 1b
chr25_+_459901 0.33 ENSDART00000154895
protogenin homolog b (Gallus gallus)
chr6_-_46589726 0.33 ENSDART00000084334
prostaglandin I2 (prostacyclin) synthase
chr15_-_34418525 0.32 ENSDART00000147582
alkylglycerol monooxygenase
chr7_-_57933736 0.32 ENSDART00000142580
ankyrin 2b, neuronal
chr6_+_52064304 0.32 ENSDART00000153468
actin binding Rho activating protein a
chr24_+_38301080 0.32 ENSDART00000105672
myosin binding protein C, fast type b
chr6_+_120181 0.31 ENSDART00000151209
ENSDART00000185930
cyclin-dependent kinase inhibitor 2D (p19, inhibits CDK4)
chr24_-_25428176 0.31 ENSDART00000090010
phosphate regulating endopeptidase homolog, X-linked
chr9_+_27411502 0.31 ENSDART00000143994
si:dkey-193n17.9
chr7_-_35516251 0.31 ENSDART00000045628
iroquois homeobox 6a
chr20_+_2281933 0.31 ENSDART00000137579
si:ch73-18b11.2
chr22_+_1796057 0.31 ENSDART00000170834
zinc finger protein 1179
chr25_+_20077225 0.30 ENSDART00000136543
troponin I4b, tandem duplicate 1
chr17_-_24564674 0.30 ENSDART00000105435
ENSDART00000135086
ATP-binding cassette, sub-family H, member 1
chr10_-_27049170 0.29 ENSDART00000143451
cornichon family AMPA receptor auxiliary protein 2
chr21_+_9666347 0.29 ENSDART00000163853
mitogen-activated protein kinase 10
chr11_+_25112269 0.29 ENSDART00000147546
ndrg family member 3a
chr6_-_35446110 0.28 ENSDART00000058773
regulator of G protein signaling 16
chr3_-_32603191 0.28 ENSDART00000150997
si:ch73-248e21.7
chr18_+_48446704 0.28 ENSDART00000134817
Fli-1 proto-oncogene, ETS transcription factor a
chr21_-_28340977 0.28 ENSDART00000141629
neurexin 2a
chr4_-_17805128 0.28 ENSDART00000128988
Spi-2 proto-oncogene
chr22_-_11136625 0.28 ENSDART00000016873
ENSDART00000125561
ATPase H+ transporting accessory protein 2
chr9_-_18424844 0.28 ENSDART00000154351
ecto-NOX disulfide-thiol exchanger 1
chr19_+_46372115 0.27 ENSDART00000163935
mediator complex subunit 30
chr19_+_32947910 0.27 ENSDART00000052091
ATPase H+ transporting V1 subunit C1b
chr21_-_22928214 0.27 ENSDART00000182760
duboraya
chr1_-_45157243 0.27 ENSDART00000131882
mucin, multiple PTS and SEA group, member 1
chr3_+_32403758 0.26 ENSDART00000156982
si:ch211-195b15.8
chr7_+_11543999 0.26 ENSDART00000173676
interleukin 16
chr23_-_26536055 0.26 ENSDART00000182719
si:dkey-205h13.2
chr10_-_27009413 0.26 ENSDART00000139942
ENSDART00000146983
ENSDART00000132352
ubiquinol-cytochrome c reductase complex assembly factor 3
chr7_+_69653981 0.25 ENSDART00000090165
Fras1 related extracellular matrix 1a
chr5_+_23118470 0.25 ENSDART00000149893
neurite extension and migration factor a
chr18_+_2222447 0.25 ENSDART00000185927
PIGB opposite strand 1
chr5_+_53824959 0.24 ENSDART00000169565
spermidine/spermine N1-acetyltransferase family member 2b
chr6_-_48087152 0.24 ENSDART00000180614
solute carrier family 2 (facilitated glucose transporter), member 1b
chr11_+_37216668 0.24 ENSDART00000173076
zgc:112265
chr16_-_29452039 0.24 ENSDART00000148960
si:ch211-113g11.6
chr16_+_26777473 0.24 ENSDART00000188870
cadherin 17, LI cadherin (liver-intestine)
chr23_+_19675780 0.24 ENSDART00000124335
small integral membrane protein 4
chr3_-_22829710 0.24 ENSDART00000055659
cytochrome b561
chr17_-_22062364 0.23 ENSDART00000114470
tau tubulin kinase 1b
chr1_+_11107688 0.23 ENSDART00000109858
kinetochore-localized astrin/SPAG5 binding protein
chr6_-_10780698 0.23 ENSDART00000151714
G protein-coupled receptor 155b
chr3_-_57744323 0.23 ENSDART00000101829
lectin, galactoside-binding, soluble, 3 binding protein b
chr17_+_27134806 0.23 ENSDART00000151901
ribosomal protein S6 kinase a, polypeptide 1
chr19_-_13286722 0.23 ENSDART00000168296
ENSDART00000158330
zinc finger protein, FOG family member 2b
chr3_+_41647637 0.23 ENSDART00000050332
guanine nucleotide binding protein (G protein) alpha 12a
chr20_+_32224405 0.22 ENSDART00000062993
ENSDART00000147448
sestrin 1
chr9_-_42861080 0.22 ENSDART00000193688
titin, tandem duplicate 1
chr3_-_32320537 0.22 ENSDART00000113550
ENSDART00000168483
si:dkey-16p21.7
chr14_+_25464681 0.22 ENSDART00000067500
ENSDART00000187601
si:dkey-280e21.3
chr11_-_29658396 0.22 ENSDART00000183947
ribosomal protein L22
chr5_-_63286077 0.21 ENSDART00000131274
tubulin folding cofactor E-like b
chr7_+_34290051 0.21 ENSDART00000123498
fin bud initiation factor b
chr7_+_42208859 0.21 ENSDART00000148643
phosphorylase kinase, beta
chr18_-_49283058 0.21 ENSDART00000076554
si:zfos-464b6.2
chr7_-_18730474 0.21 ENSDART00000170374
si:dkey-38l22.2
chr11_+_329687 0.21 ENSDART00000172882
cytochrome P450, family 27, subfamily B, polypeptide 1
chr7_-_20338048 0.21 ENSDART00000125594
zgc:194312
chr5_-_41307550 0.20 ENSDART00000143446
natriuretic peptide receptor 3
chr1_+_26411496 0.20 ENSDART00000112263
Rho guanine nucleotide exchange factor (GEF) 38
chr9_-_21230999 0.20 ENSDART00000150160
ENSDART00000102147
phospholipase A1 member A
chr24_-_982443 0.20 ENSDART00000063151
N-ethylmaleimide-sensitive factor attachment protein, gamma a
chr14_+_39255437 0.20 ENSDART00000147443
diaphanous-related formin 2
chr21_+_9576176 0.20 ENSDART00000161289
ENSDART00000159899
ENSDART00000162834
mitogen-activated protein kinase 10
chr6_+_34512313 0.20 ENSDART00000102554
low density lipoprotein receptor-related protein 8, apolipoprotein e receptor
chr18_-_15559817 0.19 ENSDART00000061681
si:ch211-245j22.3
chr19_-_25519310 0.19 ENSDART00000089882
si:dkey-202e17.1
chr1_-_59104145 0.19 ENSDART00000132495
ENSDART00000152457
si:zfos-2330d3.1
si:zfos-2330d3.7
chr22_-_32392252 0.19 ENSDART00000148681
ENSDART00000137945
poly(rC) binding protein 4
chr8_+_14058646 0.19 ENSDART00000080852
UDP glucuronosyltransferase 5 family, polypeptide E1
chr13_-_42560662 0.19 ENSDART00000124898

chr2_+_23222939 0.18 ENSDART00000026800
kinesin-associated protein 3b
chr20_+_46183505 0.18 ENSDART00000060799
trace amine associated receptor 13b
chr6_-_31348999 0.18 ENSDART00000153734
DnaJ (Hsp40) homolog, subfamily C, member 6
chr5_+_20589472 0.18 ENSDART00000130911
chemokine-like receptor 1
chr12_-_48960308 0.18 ENSDART00000176247

chr9_+_28688574 0.18 ENSDART00000101319
zgc:162396
chr25_+_18711804 0.18 ENSDART00000011149
family with sequence similarity 185, member A
chr7_+_26709251 0.18 ENSDART00000149426
ENSDART00000010323
CD82 molecule a
chr20_+_52546186 0.18 ENSDART00000110777
ENSDART00000153377
ENSDART00000153013
ENSDART00000042704
eukaryotic translation elongation factor 1 delta b (guanine nucleotide exchange protein)
chr10_+_29698467 0.17 ENSDART00000163402
discs, large homolog 2 (Drosophila)
chr18_-_8579907 0.17 ENSDART00000147284
si:ch211-220f12.1
chr23_+_44634187 0.17 ENSDART00000143688
si:ch73-265d7.2
chr2_-_32505091 0.17 ENSDART00000141884
ENSDART00000056639
Fas apoptotic inhibitory molecule 2a
chr10_-_167782 0.17 ENSDART00000108780
v-ets avian erythroblastosis virus E26 oncogene homolog
chr11_-_29936755 0.17 ENSDART00000145251
pirin
chr3_+_24189804 0.17 ENSDART00000134723
proline rich 15-like a
chr24_-_17029374 0.17 ENSDART00000039267
prostaglandin D2 synthase b, tandem duplicate 1
chr11_-_41130239 0.16 ENSDART00000173268
DnaJ (Hsp40) homolog, subfamily C, member 11b
chr6_-_49898881 0.16 ENSDART00000150204
ATP synthase F1 subunit epsilon
chr10_-_25699454 0.16 ENSDART00000064376
superoxide dismutase 1, soluble
chr14_-_2355833 0.16 ENSDART00000157677
si:ch73-233f7.6
chr2_-_9818640 0.16 ENSDART00000139499
ENSDART00000165548
ENSDART00000012442
ENSDART00000046587
adaptor-related protein complex 2, mu 1 subunit, b
chr18_-_49116382 0.16 ENSDART00000174157

chr8_+_25352268 0.16 ENSDART00000187829
deoxyribonuclease I-like 1-like
chr20_+_26538137 0.15 ENSDART00000045397
syntaxin 11b, tandem duplicate 1
chr5_-_26950374 0.15 ENSDART00000050542
HtrA serine peptidase 4
chr2_+_36862473 0.15 ENSDART00000135624
si:dkey-193b15.8
chr14_+_33413980 0.15 ENSDART00000052780
ENSDART00000124437
ENSDART00000173327
NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 1
chr16_-_22192006 0.15 ENSDART00000163338
interleukin 6 receptor
chr23_-_29502287 0.15 ENSDART00000141075
ENSDART00000053807
kinesin family member 1B
chr6_-_51101834 0.15 ENSDART00000092493
protein tyrosine phosphatase, receptor type, t
chr18_+_8231138 0.15 ENSDART00000140193
arylsulfatase A
chr19_-_8962884 0.15 ENSDART00000172582
ENSDART00000104657
mitochondrial ribosomal protein S21
chr2_-_9816492 0.15 ENSDART00000138472
ENSDART00000124051
adaptor-related protein complex 2, mu 1 subunit, b
chr8_-_25327809 0.15 ENSDART00000137242
EPS8-like 3b
chr2_-_32356539 0.14 ENSDART00000169316
ArfGAP with SH3 domain, ankyrin repeat and PH domain 1a
chr7_-_5316901 0.14 ENSDART00000181505
ENSDART00000124367
si:cabz01074946.1
chr7_+_54617060 0.14 ENSDART00000158898
fibroblast growth factor 4
chr10_-_41664427 0.14 ENSDART00000150213
gamma-glutamyltransferase 1b
chr8_+_53452681 0.14 ENSDART00000166705
calcium channel, voltage-dependent, L type, alpha 1D subunit, b
chr4_+_25693463 0.14 ENSDART00000132864
acyl-CoA thioesterase 18
chr20_-_27864964 0.14 ENSDART00000153311
synapse differentiation inducing 1-like
chr24_+_926258 0.14 ENSDART00000153654
piezo-type mechanosensitive ion channel component 2a, tandem duplicate 2
chr16_+_42829735 0.13 ENSDART00000014956
polymerase (RNA) III (DNA directed) polypeptide G like b
chr11_-_22372072 0.13 ENSDART00000065996
transmembrane protein 183A
chr17_+_24006792 0.13 ENSDART00000122415
si:ch211-63b16.4
chr6_+_9163007 0.13 ENSDART00000183054
ENSDART00000157552
zgc:112023
chr25_+_32474031 0.13 ENSDART00000152124
sulfide quinone oxidoreductase
chr2_+_30721466 0.13 ENSDART00000128982
si:dkey-94e7.2
chr17_+_45009868 0.13 ENSDART00000085009
coenzyme Q6 monooxygenase
chr8_-_40075983 0.13 ENSDART00000141455
gamma-glutamyltransferase 1a

Network of associatons between targets according to the STRING database.

First level regulatory network of maff+mafga+mafgb

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 2.7 GO:0015671 oxygen transport(GO:0015671)
0.1 0.8 GO:0001839 neural plate morphogenesis(GO:0001839)
0.1 0.5 GO:2000048 negative regulation of cell-cell adhesion mediated by cadherin(GO:2000048)
0.1 0.4 GO:0007638 mechanosensory behavior(GO:0007638)
0.1 0.5 GO:0007217 tachykinin receptor signaling pathway(GO:0007217)
0.1 0.5 GO:0030219 megakaryocyte differentiation(GO:0030219)
0.1 0.5 GO:1903361 protein localization to basolateral plasma membrane(GO:1903361)
0.1 0.3 GO:0061341 non-canonical Wnt signaling pathway involved in heart development(GO:0061341)
0.1 0.9 GO:0008090 retrograde axonal transport(GO:0008090)
0.1 0.3 GO:0061549 sympathetic ganglion development(GO:0061549)
0.1 0.3 GO:0019242 methylglyoxal biosynthetic process(GO:0019242) glyceraldehyde-3-phosphate biosynthetic process(GO:0046166)
0.1 0.7 GO:0099550 trans-synaptic signalling, modulating synaptic transmission(GO:0099550)
0.1 0.3 GO:0046485 ether lipid metabolic process(GO:0046485)
0.1 0.8 GO:0006123 mitochondrial electron transport, cytochrome c to oxygen(GO:0006123)
0.1 0.3 GO:0036371 protein localization to T-tubule(GO:0036371)
0.1 0.8 GO:0009435 NAD biosynthetic process(GO:0009435)
0.1 0.3 GO:0007624 ultradian rhythm(GO:0007624)
0.1 0.5 GO:0051965 positive regulation of synapse assembly(GO:0051965)
0.1 0.3 GO:0031179 peptide modification(GO:0031179)
0.0 0.1 GO:0048917 posterior lateral line ganglion development(GO:0048917)
0.0 0.2 GO:0051988 regulation of attachment of spindle microtubules to kinetochore(GO:0051988)
0.0 0.1 GO:0070221 sulfide oxidation(GO:0019418) sulfide oxidation, using sulfide:quinone oxidoreductase(GO:0070221)
0.0 0.3 GO:0017062 respiratory chain complex III assembly(GO:0017062) mitochondrial respiratory chain complex III assembly(GO:0034551) mitochondrial respiratory chain complex III biogenesis(GO:0097033)
0.0 0.2 GO:0030224 monocyte differentiation(GO:0030224)
0.0 0.1 GO:0045040 outer mitochondrial membrane organization(GO:0007008) protein import into mitochondrial outer membrane(GO:0045040)
0.0 0.2 GO:0048025 negative regulation of RNA splicing(GO:0033119) negative regulation of mRNA splicing, via spliceosome(GO:0048025)
0.0 0.1 GO:1901232 regulation of convergent extension involved in axis elongation(GO:1901232) positive regulation of epiboly involved in gastrulation with mouth forming second(GO:1904088)
0.0 0.2 GO:0098529 neuromuscular junction development, skeletal muscle fiber(GO:0098529)
0.0 0.2 GO:0016191 synaptic vesicle uncoating(GO:0016191)
0.0 0.6 GO:0000737 DNA catabolic process, endonucleolytic(GO:0000737)
0.0 0.2 GO:0032918 polyamine acetylation(GO:0032917) spermidine acetylation(GO:0032918)
0.0 0.1 GO:0010312 detoxification of zinc ion(GO:0010312) stress response to zinc ion(GO:1990359)
0.0 0.2 GO:1901031 response to leucine(GO:0043201) cellular response to leucine(GO:0071233) regulation of response to reactive oxygen species(GO:1901031)
0.0 0.4 GO:0051127 positive regulation of actin nucleation(GO:0051127) positive regulation of Arp2/3 complex-mediated actin nucleation(GO:2000601)
0.0 0.5 GO:0036376 cellular potassium ion homeostasis(GO:0030007) sodium ion export from cell(GO:0036376) sodium ion export(GO:0071436)
0.0 0.1 GO:0009838 abscission(GO:0009838) mitotic cytokinesis checkpoint(GO:0044878)
0.0 0.1 GO:0009162 deoxyribonucleoside monophosphate metabolic process(GO:0009162)
0.0 0.4 GO:0036444 calcium ion transmembrane import into mitochondrion(GO:0036444)
0.0 0.5 GO:0031952 regulation of protein autophosphorylation(GO:0031952)
0.0 0.1 GO:1900029 positive regulation of ruffle assembly(GO:1900029)
0.0 0.6 GO:0015986 energy coupled proton transport, down electrochemical gradient(GO:0015985) ATP synthesis coupled proton transport(GO:0015986)
0.0 0.2 GO:0050911 detection of chemical stimulus involved in sensory perception of smell(GO:0050911)
0.0 0.2 GO:0048662 regulation of smooth muscle cell proliferation(GO:0048660) negative regulation of smooth muscle cell proliferation(GO:0048662)
0.0 0.1 GO:0071260 cellular response to mechanical stimulus(GO:0071260)
0.0 0.3 GO:0046457 prostaglandin biosynthetic process(GO:0001516) prostanoid biosynthetic process(GO:0046457)
0.0 0.1 GO:0006086 acetyl-CoA biosynthetic process from pyruvate(GO:0006086)
0.0 0.3 GO:0035970 peptidyl-threonine dephosphorylation(GO:0035970)
0.0 0.4 GO:0061074 regulation of neural retina development(GO:0061074)
0.0 0.5 GO:0035435 phosphate ion transmembrane transport(GO:0035435)
0.0 0.2 GO:0007023 post-chaperonin tubulin folding pathway(GO:0007023)
0.0 0.1 GO:1903146 regulation of mitophagy(GO:1903146)
0.0 0.3 GO:0048769 sarcomerogenesis(GO:0048769)
0.0 0.1 GO:0071467 cellular response to pH(GO:0071467)
0.0 0.6 GO:0006891 intra-Golgi vesicle-mediated transport(GO:0006891)
0.0 0.1 GO:0031444 slow-twitch skeletal muscle fiber contraction(GO:0031444)
0.0 0.7 GO:1902600 hydrogen ion transmembrane transport(GO:1902600)
0.0 0.2 GO:1990748 response to superoxide(GO:0000303) response to oxygen radical(GO:0000305) removal of superoxide radicals(GO:0019430) cellular response to oxygen radical(GO:0071450) cellular response to superoxide(GO:0071451) cellular oxidant detoxification(GO:0098869) cellular detoxification(GO:1990748)
0.0 0.6 GO:0010921 regulation of phosphatase activity(GO:0010921)
0.0 0.2 GO:0060217 hemangioblast cell differentiation(GO:0060217)
0.0 0.2 GO:0042407 cristae formation(GO:0042407)
0.0 0.7 GO:0030968 endoplasmic reticulum unfolded protein response(GO:0030968)
0.0 0.1 GO:0003321 positive regulation of heart rate by epinephrine-norepinephrine(GO:0001996) positive regulation of blood pressure by epinephrine-norepinephrine(GO:0003321) positive regulation of heart rate(GO:0010460)
0.0 0.3 GO:0030032 lamellipodium assembly(GO:0030032)
0.0 0.3 GO:0050927 regulation of positive chemotaxis(GO:0050926) positive regulation of positive chemotaxis(GO:0050927) induction of positive chemotaxis(GO:0050930)
0.0 0.1 GO:0051013 microtubule severing(GO:0051013)
0.0 0.2 GO:0071594 T cell differentiation in thymus(GO:0033077) thymocyte aggregation(GO:0071594)
0.0 0.1 GO:0032218 riboflavin transport(GO:0032218)
0.0 0.2 GO:0001867 complement activation, lectin pathway(GO:0001867)
0.0 0.2 GO:0071425 hematopoietic stem cell proliferation(GO:0071425)
0.0 0.9 GO:0048741 myotube cell development(GO:0014904) skeletal muscle fiber development(GO:0048741)
0.0 0.1 GO:1903523 negative regulation of heart contraction(GO:0045822) negative regulation of blood circulation(GO:1903523)
0.0 0.1 GO:0071340 skeletal muscle acetylcholine-gated channel clustering(GO:0071340)
0.0 0.8 GO:0008045 motor neuron axon guidance(GO:0008045)
0.0 0.3 GO:0035622 intrahepatic bile duct development(GO:0035622)
0.0 0.0 GO:0070285 pigment cell development(GO:0070285)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 2.7 GO:0031838 haptoglobin-hemoglobin complex(GO:0031838)
0.1 0.5 GO:0097025 MPP7-DLG1-LIN7 complex(GO:0097025)
0.1 0.3 GO:0043190 ATP-binding cassette (ABC) transporter complex(GO:0043190)
0.1 0.4 GO:0033181 plasma membrane proton-transporting V-type ATPase complex(GO:0033181)
0.1 0.8 GO:0005751 mitochondrial respiratory chain complex IV(GO:0005751)
0.1 0.9 GO:0005869 dynactin complex(GO:0005869)
0.1 0.6 GO:0005964 phosphorylase kinase complex(GO:0005964)
0.0 0.2 GO:0000275 mitochondrial proton-transporting ATP synthase complex, catalytic core F(1)(GO:0000275)
0.0 0.3 GO:0000221 vacuolar proton-transporting V-type ATPase, V1 domain(GO:0000221)
0.0 0.4 GO:1990246 uniplex complex(GO:1990246)
0.0 0.1 GO:0008352 katanin complex(GO:0008352)
0.0 0.3 GO:0030122 AP-2 adaptor complex(GO:0030122)
0.0 0.2 GO:0061700 GATOR2 complex(GO:0061700)
0.0 0.4 GO:0000276 mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)(GO:0000276)
0.0 0.4 GO:0031209 SCAR complex(GO:0031209)
0.0 0.3 GO:0045275 mitochondrial respiratory chain complex III(GO:0005750) respiratory chain complex III(GO:0045275)
0.0 0.2 GO:0031526 brush border membrane(GO:0031526)
0.0 0.2 GO:0005853 eukaryotic translation elongation factor 1 complex(GO:0005853)
0.0 0.2 GO:0034451 centriolar satellite(GO:0034451)
0.0 0.1 GO:0005967 mitochondrial pyruvate dehydrogenase complex(GO:0005967)
0.0 0.3 GO:0030315 T-tubule(GO:0030315)
0.0 0.4 GO:0034706 voltage-gated sodium channel complex(GO:0001518) sodium channel complex(GO:0034706)
0.0 0.3 GO:0032591 dendritic spine membrane(GO:0032591)
0.0 0.5 GO:0000159 protein phosphatase type 2A complex(GO:0000159)
0.0 0.1 GO:0001401 mitochondrial sorting and assembly machinery complex(GO:0001401)
0.0 0.2 GO:0061617 MICOS complex(GO:0061617)
0.0 0.1 GO:0031314 extrinsic component of mitochondrial inner membrane(GO:0031314)
0.0 0.0 GO:0044316 cone cell pedicle(GO:0044316)
0.0 0.1 GO:0060171 stereocilium membrane(GO:0060171)
0.0 0.4 GO:0032281 AMPA glutamate receptor complex(GO:0032281)
0.0 0.1 GO:0005744 mitochondrial inner membrane presequence translocase complex(GO:0005744)
0.0 0.4 GO:0005861 troponin complex(GO:0005861)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 0.8 GO:0048030 disaccharide binding(GO:0048030)
0.2 0.7 GO:1990430 extracellular matrix protein binding(GO:1990430)
0.2 2.7 GO:0031720 haptoglobin binding(GO:0031720)
0.2 0.5 GO:0031834 neurokinin receptor binding(GO:0031834) substance P receptor binding(GO:0031835)
0.1 0.5 GO:0097016 L27 domain binding(GO:0097016)
0.1 0.3 GO:1901612 cardiolipin binding(GO:1901612)
0.1 0.4 GO:0008432 JUN kinase binding(GO:0008432)
0.1 0.3 GO:0008929 triose-phosphate isomerase activity(GO:0004807) methylglyoxal synthase activity(GO:0008929)
0.1 0.2 GO:0000293 ferric-chelate reductase activity(GO:0000293)
0.1 0.2 GO:0031752 D5 dopamine receptor binding(GO:0031752)
0.1 0.7 GO:0004865 protein serine/threonine phosphatase inhibitor activity(GO:0004865)
0.1 0.6 GO:0004530 deoxyribonuclease I activity(GO:0004530)
0.1 0.3 GO:0042609 CD4 receptor binding(GO:0042609)
0.1 0.5 GO:0005391 sodium:potassium-exchanging ATPase activity(GO:0005391)
0.1 0.4 GO:0055056 D-glucose transmembrane transporter activity(GO:0055056)
0.0 0.5 GO:0004705 JUN kinase activity(GO:0004705) SAP kinase activity(GO:0016909)
0.0 0.4 GO:0015467 G-protein activated inward rectifier potassium channel activity(GO:0015467)
0.0 0.4 GO:0071933 Arp2/3 complex binding(GO:0071933)
0.0 0.3 GO:0036374 peptidyltransferase activity(GO:0000048) glutathione hydrolase activity(GO:0036374)
0.0 0.8 GO:0070566 adenylyltransferase activity(GO:0070566)
0.0 0.1 GO:0070224 sulfide:quinone oxidoreductase activity(GO:0070224)
0.0 0.1 GO:0005183 gonadotropin hormone-releasing hormone activity(GO:0005183) gonadotropin-releasing hormone receptor binding(GO:0031530)
0.0 0.3 GO:0016714 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced pteridine as one donor, and incorporation of one atom of oxygen(GO:0016714)
0.0 0.2 GO:0019809 spermidine binding(GO:0019809)
0.0 0.2 GO:0005483 soluble NSF attachment protein activity(GO:0005483)
0.0 0.2 GO:0070728 leucine binding(GO:0070728)
0.0 0.5 GO:0005315 inorganic phosphate transmembrane transporter activity(GO:0005315)
0.0 0.8 GO:0004129 cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors(GO:0016675) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676)
0.0 0.0 GO:0019808 polyamine binding(GO:0019808)
0.0 0.4 GO:0004971 AMPA glutamate receptor activity(GO:0004971)
0.0 0.5 GO:0072542 phosphatase activator activity(GO:0019211) protein phosphatase activator activity(GO:0072542)
0.0 0.1 GO:0004739 pyruvate dehydrogenase (acetyl-transferring) activity(GO:0004739)
0.0 0.1 GO:0004984 olfactory receptor activity(GO:0004984)
0.0 0.1 GO:0044736 acid-sensing ion channel activity(GO:0044736)
0.0 0.2 GO:0001972 retinoic acid binding(GO:0001972)
0.0 0.3 GO:0008330 protein tyrosine/threonine phosphatase activity(GO:0008330)
0.0 0.2 GO:0016721 superoxide dismutase activity(GO:0004784) oxidoreductase activity, acting on superoxide radicals as acceptor(GO:0016721)
0.0 0.1 GO:0015450 P-P-bond-hydrolysis-driven protein transmembrane transporter activity(GO:0015450)
0.0 0.2 GO:0004711 ribosomal protein S6 kinase activity(GO:0004711)
0.0 0.4 GO:1905030 voltage-gated sodium channel activity(GO:0005248) voltage-gated ion channel activity involved in regulation of postsynaptic membrane potential(GO:1905030)
0.0 0.2 GO:0043014 alpha-tubulin binding(GO:0043014)
0.0 0.1 GO:0036042 long-chain fatty acyl-CoA binding(GO:0036042)
0.0 0.3 GO:0004190 aspartic-type endopeptidase activity(GO:0004190) aspartic-type peptidase activity(GO:0070001)
0.0 0.0 GO:0008397 sterol 12-alpha-hydroxylase activity(GO:0008397)
0.0 0.0 GO:0047256 beta-galactosyl-N-acetylglucosaminylgalactosylglucosyl-ceramide beta-1,3-acetylglucosaminyltransferase activity(GO:0008457) lactosylceramide 1,3-N-acetyl-beta-D-glucosaminyltransferase activity(GO:0047256)
0.0 0.6 GO:0005184 neuropeptide hormone activity(GO:0005184)
0.0 0.2 GO:0046933 proton-transporting ATP synthase activity, rotational mechanism(GO:0046933)
0.0 0.2 GO:0004955 prostaglandin receptor activity(GO:0004955)
0.0 0.1 GO:0004937 alpha1-adrenergic receptor activity(GO:0004937)
0.0 0.3 GO:0046961 ATPase activity, coupled to transmembrane movement of ions, rotational mechanism(GO:0044769) proton-transporting ATPase activity, rotational mechanism(GO:0046961)
0.0 0.1 GO:0032217 riboflavin transporter activity(GO:0032217)
0.0 0.1 GO:0004046 aminoacylase activity(GO:0004046)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.9 ST GRANULE CELL SURVIVAL PATHWAY Granule Cell Survival Pathway is a specific case of more general PAC1 Receptor Pathway.
0.0 0.4 ST G ALPHA S PATHWAY G alpha s Pathway
0.0 0.2 ST STAT3 PATHWAY STAT3 Pathway
0.0 0.5 NABA COLLAGENS Genes encoding collagen proteins
0.0 0.3 PID WNT SIGNALING PATHWAY Wnt signaling network
0.0 0.9 NABA ECM AFFILIATED Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.4 REACTOME REGULATION OF COMPLEMENT CASCADE Genes involved in Regulation of Complement cascade
0.1 0.7 REACTOME SYNTHESIS SECRETION AND INACTIVATION OF GLP1 Genes involved in Synthesis, Secretion, and Inactivation of Glucagon-like Peptide-1 (GLP-1)
0.1 0.7 REACTOME PLATELET SENSITIZATION BY LDL Genes involved in Platelet sensitization by LDL
0.0 0.5 REACTOME ACTIVATION OF THE AP1 FAMILY OF TRANSCRIPTION FACTORS Genes involved in Activation of the AP-1 family of transcription factors
0.0 0.6 REACTOME GLYCOGEN BREAKDOWN GLYCOGENOLYSIS Genes involved in Glycogen breakdown (glycogenolysis)
0.0 0.2 REACTOME PROSTANOID LIGAND RECEPTORS Genes involved in Prostanoid ligand receptors
0.0 0.1 REACTOME SIGNALING BY ACTIVATED POINT MUTANTS OF FGFR1 Genes involved in Signaling by activated point mutants of FGFR1
0.0 0.5 REACTOME CYTOCHROME P450 ARRANGED BY SUBSTRATE TYPE Genes involved in Cytochrome P450 - arranged by substrate type
0.0 0.2 REACTOME CREB PHOSPHORYLATION THROUGH THE ACTIVATION OF RAS Genes involved in CREB phosphorylation through the activation of Ras
0.0 0.1 REACTOME FACILITATIVE NA INDEPENDENT GLUCOSE TRANSPORTERS Genes involved in Facilitative Na+-independent glucose transporters
0.0 0.4 REACTOME COMPLEMENT CASCADE Genes involved in Complement cascade
0.0 0.2 REACTOME IL 6 SIGNALING Genes involved in Interleukin-6 signaling
0.0 0.8 REACTOME METABOLISM OF VITAMINS AND COFACTORS Genes involved in Metabolism of vitamins and cofactors
0.0 0.5 REACTOME NCAM1 INTERACTIONS Genes involved in NCAM1 interactions
0.0 0.1 REACTOME THE ACTIVATION OF ARYLSULFATASES Genes involved in The activation of arylsulfatases
0.0 0.1 REACTOME EICOSANOID LIGAND BINDING RECEPTORS Genes involved in Eicosanoid ligand-binding receptors
0.0 0.1 REACTOME REGULATION OF PYRUVATE DEHYDROGENASE PDH COMPLEX Genes involved in Regulation of pyruvate dehydrogenase (PDH) complex