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PRJNA195909:zebrafish embryo and larva development

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Results for klf12b

Z-value: 1.16

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Transcription factors associated with klf12b

Gene Symbol Gene ID Gene Info
ENSDARG00000032197 Kruppel-like factor 12b

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
klf12bdr11_v1_chr9_+_30720048_307200480.827.3e-03Click!

Activity profile of klf12b motif

Sorted Z-values of klf12b motif

Promoter Log-likelihood Transcript Gene Gene Info
chr6_+_13742899 2.17 ENSDART00000104722
cyclin-dependent kinase 5, regulatory subunit 2a (p39)
chr21_+_25187210 2.07 ENSDART00000101147
ENSDART00000167528
si:dkey-183i3.5
chr5_-_67471375 1.47 ENSDART00000147009
si:dkey-251i10.2
chr13_-_39947335 1.28 ENSDART00000056996
secreted frizzled-related protein 5
chr13_-_39159810 1.23 ENSDART00000131508
collagen, type IX, alpha 1b
chr19_-_4010263 1.20 ENSDART00000159605
ENSDART00000165541
MAP7 domain containing 1b
chr13_+_13681681 1.19 ENSDART00000057825
complement factor D (adipsin)
chr20_-_22484621 1.16 ENSDART00000063601
GS homeobox 2
chr15_+_1397811 1.12 ENSDART00000102125
schwannomin interacting protein 1
chr12_+_42574148 1.10 ENSDART00000157855
early B cell factor 3a
chr7_-_43840680 1.09 ENSDART00000002279
cadherin 11, type 2, OB-cadherin (osteoblast)
chr6_+_24817852 1.07 ENSDART00000165609
BarH-like homeobox 2
chr17_+_15433518 1.05 ENSDART00000026180
fatty acid binding protein 7, brain, a
chr25_-_31423493 1.02 ENSDART00000027661
myogenic differentiation 1
chr23_+_35714574 0.91 ENSDART00000164616
tubulin, alpha 1c
chr15_-_37846047 0.90 ENSDART00000184837
heat shock cognate 70
chr20_+_15015557 0.87 ENSDART00000039345
myocilin
chr2_+_47582681 0.86 ENSDART00000187579
secretogranin II (chromogranin C), b
chr16_+_23947196 0.84 ENSDART00000103190
ENSDART00000132961
ENSDART00000147690
ENSDART00000142168
apolipoprotein A-IV b, tandem duplicate 2
chr5_-_28679135 0.81 ENSDART00000193585
tenascin C
chr13_-_31470439 0.80 ENSDART00000076574
reticulon 1a
chr4_-_16353733 0.80 ENSDART00000186785
lumican
chr16_+_20926673 0.76 ENSDART00000009827
homeobox A2b
chr14_-_45206999 0.76 ENSDART00000110191
shisa family member 3
chr3_+_15505275 0.75 ENSDART00000141714
nuclear protein 1
chr16_-_2414063 0.75 ENSDART00000073621
zgc:152945
chr25_+_15647750 0.75 ENSDART00000137375
spondin 1b
chr11_+_23957440 0.74 ENSDART00000190721
contactin 2
chr13_-_11536951 0.74 ENSDART00000018155
adenylosuccinate synthase
chr7_-_30082931 0.74 ENSDART00000075600
tetraspanin 3b
chr1_-_44434707 0.73 ENSDART00000110148
crystallin, beta A1, like 2
chr13_+_25449681 0.72 ENSDART00000101328
atonal bHLH transcription factor 7
chr4_+_6643421 0.71 ENSDART00000099462
G protein-coupled receptor 85
chr19_-_26863626 0.71 ENSDART00000145568
proline-rich transmembrane protein 1
chr17_-_15546862 0.71 ENSDART00000091021
collagen, type X, alpha 1a
chr18_+_18104235 0.69 ENSDART00000145342
cerebellin 1 precursor
chr2_-_29485408 0.69 ENSDART00000013411
carbonic anhydrase
chr22_-_2886937 0.68 ENSDART00000063533
aquaporin 12
chr17_+_10242166 0.68 ENSDART00000170420
C-type lectin domain containing 14A
chr2_+_27010439 0.67 ENSDART00000030547
cadherin 7a
chr2_+_33368414 0.67 ENSDART00000077462
solute carrier family 6 (neurotransmitter transporter, glycine), member 9
chr23_-_39636195 0.65 ENSDART00000144439
von Willebrand factor A domain containing 1
chr8_+_26565512 0.65 ENSDART00000140980
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3bl
chr17_-_49978986 0.65 ENSDART00000154728
collagen, type XII, alpha 1a
chr20_-_26001288 0.65 ENSDART00000136518
ENSDART00000063177
calpain 3b
chr5_-_65782783 0.65 ENSDART00000130888
ENSDART00000050855
notch 1b
chr20_+_1412193 0.64 ENSDART00000064419
liver-enriched gene 1, tandem duplicate 1
chr6_+_49881864 0.64 ENSDART00000075040
tubulin, beta 1 class VI
chr20_-_44496245 0.64 ENSDART00000012229
FK506 binding protein 1b
chr12_+_13164706 0.64 ENSDART00000112565
progestin and adipoQ receptor family member IVb
chr24_+_7637522 0.64 ENSDART00000082467
caveolae associated protein 1b
chr2_+_22042745 0.64 ENSDART00000132039
thymocyte selection-associated high mobility group box
chr17_+_18117358 0.64 ENSDART00000144894
B cell CLL/lymphoma 11Ba
chr15_+_37197494 0.63 ENSDART00000166203
amyloid beta (A4) precursor-like protein 1
chr17_-_52643970 0.62 ENSDART00000190594
sprouty-related, EVH1 domain containing 1
chr21_+_29077509 0.62 ENSDART00000128561
endothelial cell surface expressed chemotaxis and apoptosis regulator
chr9_-_1939232 0.61 ENSDART00000146131
homeobox D3a
chr9_-_35155089 0.61 ENSDART00000077901
amyloid beta (A4) precursor protein b
chr2_-_65529 0.60 ENSDART00000192876
zgc:153913
chr4_-_4834617 0.60 ENSDART00000141539
cytochrome c oxidase assembly factor 6
chr22_-_23666504 0.59 ENSDART00000158665
complement factor H
chr4_-_1324141 0.59 ENSDART00000180720
pleiotrophin
chr13_+_19322686 0.59 ENSDART00000058036
empty spiracles homeobox 2
chr20_-_47704973 0.59 ENSDART00000174808
transcription factor AP-2 beta
chr18_+_9171778 0.58 ENSDART00000101192
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3D
chr23_+_22658700 0.58 ENSDART00000192248
enolase 1a, (alpha)
chr23_+_8797143 0.57 ENSDART00000132992
SRY (sex determining region Y)-box 18
chr11_+_36989696 0.56 ENSDART00000045888
transketolase a
chr24_+_24461558 0.55 ENSDART00000182424
basic helix-loop-helix family, member e22
chr6_-_49215790 0.55 ENSDART00000103376
ENSDART00000132347
ENSDART00000132131
ENSDART00000143252
ENSDART00000065033
nerve growth factor b (beta polypeptide)
chr18_+_20494413 0.55 ENSDART00000060295
receptor-associated protein of the synapse, 43kD
chr22_-_26353916 0.54 ENSDART00000077958
calpain 2, (m/II) large subunit b
chr3_+_28953274 0.54 ENSDART00000133528
ENSDART00000103602
lectin, galactoside-binding, soluble, 2a
chr14_-_36863432 0.54 ENSDART00000158052
ring finger protein 130
chr4_+_5741733 0.54 ENSDART00000110243
POU class 3 homeobox 2a
chr19_+_27479838 0.53 ENSDART00000103922
alpha tubulin acetyltransferase 1
chr8_-_14144707 0.53 ENSDART00000148061
si:dkey-6n6.1
chr14_+_32022272 0.53 ENSDART00000105760
zic family member 6
chr12_+_16233077 0.53 ENSDART00000152409
membrane protein, palmitoylated 3b (MAGUK p55 subfamily member 3)
chr12_+_24344963 0.53 ENSDART00000191648
ENSDART00000183180
ENSDART00000088178
ENSDART00000189696
neurexin 1a
chr17_+_18117029 0.53 ENSDART00000154646
ENSDART00000179739
B cell CLL/lymphoma 11Ba
chr3_+_23738215 0.52 ENSDART00000143981
homeobox B3a
chr20_-_19422496 0.52 ENSDART00000143658
si:ch211-278j3.3
chr16_-_12809873 0.52 ENSDART00000146997
ENSDART00000178291
ENSDART00000007842
isochorismatase domain containing 2
chr19_+_37458610 0.52 ENSDART00000103151
discs, large (Drosophila) homolog-associated protein 3
chr4_+_15954293 0.51 ENSDART00000132695
si:dkey-117n7.4
chr17_+_51627209 0.51 ENSDART00000056886
zgc:113142
chr16_-_12173554 0.50 ENSDART00000110567
ENSDART00000155935
calsyntenin 3
chr11_-_42554290 0.50 ENSDART00000130573
ATPase H+ transporting accessory protein 1 like a
chr22_-_5006801 0.49 ENSDART00000106166
retinal homeobox gene 1
chr11_+_23933016 0.49 ENSDART00000000486
contactin 2
chr3_-_30685401 0.49 ENSDART00000151097
si:ch211-51c14.1
chr9_-_31278048 0.48 ENSDART00000022204
zic family member 5 (odd-paired homolog, Drosophila)
chr18_-_22753637 0.48 ENSDART00000181589
ENSDART00000009912
heat shock transcription factor 4
chr5_+_54585431 0.48 ENSDART00000171225
natriuretic peptide receptor 2
chr8_-_9118958 0.48 ENSDART00000037922
solute carrier family 6 (neurotransmitter transporter), member 8
chr24_+_7637264 0.47 ENSDART00000124409
caveolae associated protein 1b
chr22_+_12431608 0.47 ENSDART00000108609
Rho family GTPase 3a
chr3_-_38692920 0.47 ENSDART00000155042
membrane protein, palmitoylated 3a (MAGUK p55 subfamily member 3)
chr4_+_19535946 0.46 ENSDART00000192342
ENSDART00000183740
ENSDART00000180812
ENSDART00000180017
leucine rich repeat containing 4.1
chr14_-_30704075 0.46 ENSDART00000134098
EGF containing fibulin extracellular matrix protein 2a
chr10_+_22381802 0.46 ENSDART00000112484
neuroligin 2b
chr7_+_44713135 0.45 ENSDART00000170721
si:dkey-56m19.5
chr22_-_10482253 0.45 ENSDART00000143164
asporin (LRR class 1)
chr22_-_600016 0.45 ENSDART00000086434
transmembrane and coiled-coil domain family 2
chr6_-_20875111 0.45 ENSDART00000115118
ENSDART00000159916
tensin 1a
chr15_+_15415623 0.44 ENSDART00000127436
zgc:92630
chr14_-_39074539 0.44 ENSDART00000030509
glycine receptor, alpha 4a
chr25_-_15040369 0.44 ENSDART00000159342
ENSDART00000166490
paired box 6a
chr4_-_4834347 0.44 ENSDART00000141803
cytochrome c oxidase assembly factor 6
chr22_-_11626014 0.44 ENSDART00000063133
ENSDART00000160085
glucagon a
chr20_+_26349002 0.44 ENSDART00000152842
spectrin repeat containing, nuclear envelope 1a
chr1_-_35653560 0.44 ENSDART00000142154
Fras1 related extracellular matrix 3
chr17_-_36896560 0.44 ENSDART00000045287
microtubule-associated protein, RP/EB family, member 3a
chr4_-_6809323 0.44 ENSDART00000099467
interferon-related developmental regulator 1
chr1_+_27112479 0.44 ENSDART00000128671
basonuclin 2
chr11_-_37509001 0.43 ENSDART00000109753
bassoon (presynaptic cytomatrix protein) b
chr4_-_18201622 0.43 ENSDART00000133509
ankyrin repeat and sterile alpha motif domain containing 1B
chr14_+_36223097 0.43 ENSDART00000186872
paired-like homeodomain 2
chr5_+_52039067 0.43 ENSDART00000143276
SET binding protein 1
chr7_+_26224211 0.43 ENSDART00000173999
VGF nerve growth factor inducible
chr10_+_21776911 0.42 ENSDART00000163077
ENSDART00000186093
protocadherin 1 gamma 22
chr18_+_17583479 0.41 ENSDART00000186977
ENSDART00000010998
solute carrier family 12 (sodium/chloride transporter), member 3
chr1_+_59073203 0.41 ENSDART00000149937
ENSDART00000162201
si:zfos-2330d3.3
zgc:173915
chr7_-_57933736 0.41 ENSDART00000142580
ankyrin 2b, neuronal
chr12_+_2381213 0.41 ENSDART00000188007

chr25_-_30357027 0.41 ENSDART00000171137
protein disulfide isomerase family A, member 3
chr14_-_26377044 0.41 ENSDART00000022236
empty spiracles homeobox 3
chr15_+_32821392 0.41 ENSDART00000158272
doublecortin-like kinase 1b
chr8_+_42998944 0.41 ENSDART00000048819
Ras association (RalGDS/AF-6) domain family member 2a
chr23_-_23401305 0.40 ENSDART00000078936
hairy-related 9
chr9_-_21970067 0.40 ENSDART00000009920
LIM domain 7a
chr21_+_17768174 0.40 ENSDART00000141380
retinoid X receptor, alpha a
chr5_-_55395964 0.40 ENSDART00000145791
prune homolog 2 (Drosophila)
chr24_+_18948665 0.39 ENSDART00000106186
phosphatidylinositol-3,4,5-trisphosphate-dependent Rac exchange factor 2
chr13_+_31108334 0.39 ENSDART00000142245
Rho GTPase activating protein 22
chr8_+_31119548 0.39 ENSDART00000136578
synapsin I
chr21_-_44104600 0.39 ENSDART00000044599
organic anion transporter X
chr16_-_44512882 0.39 ENSDART00000191241

chr23_-_8373676 0.38 ENSDART00000105135
ENSDART00000158531
opiate receptor-like 1
chr8_-_53108207 0.38 ENSDART00000111023
UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 4
chr12_+_13905286 0.38 ENSDART00000147186
FK506 binding protein 10b
chr18_-_45617146 0.38 ENSDART00000146543
wilms tumor 1b
chr12_-_212843 0.38 ENSDART00000083574

chr5_-_23317477 0.37 ENSDART00000090171
neuroligin 3b
chr15_-_20916251 0.37 ENSDART00000134053
ubiquitin specific peptidase 2a
chr12_+_9817440 0.37 ENSDART00000137081
ENSDART00000123712
RUN domain containing 3Ab
chr23_+_44883805 0.37 ENSDART00000182805
si:ch73-361h17.1
chr1_+_59090972 0.37 ENSDART00000171497
microfibril associated protein 4
chr10_-_43771447 0.37 ENSDART00000052307
arrestin domain containing 3b
chr7_+_11197940 0.37 ENSDART00000081346
cell migration inducing protein, hyaluronan binding
chr3_-_32320537 0.37 ENSDART00000113550
ENSDART00000168483
si:dkey-16p21.7
chr1_+_59090743 0.36 ENSDART00000100199
microfibril associated protein 4
chr2_+_22694382 0.36 ENSDART00000139196
kinesin family member 1Ab
chr15_-_8517555 0.36 ENSDART00000140213
neuronal PAS domain protein 1
chr2_-_10703621 0.36 ENSDART00000005944
ribosomal protein L5a
chr21_-_12272543 0.36 ENSDART00000081510
ENSDART00000151297
CUGBP, Elav-like family member 4
chr5_-_38506981 0.35 ENSDART00000097822
ATPase Na+/K+ transporting subunit beta 2b
chr20_+_539852 0.35 ENSDART00000185994
dermatan sulfate epimerase
chr22_+_5727753 0.35 ENSDART00000063484
si:dkey-222f2.1
chr2_-_20599315 0.35 ENSDART00000114199
si:ch211-267e7.3
chr17_-_24684687 0.34 ENSDART00000105457
MORN repeat containing 2
chr8_-_14050758 0.34 ENSDART00000133922
ATPase plasma membrane Ca2+ transporting 3a
chr13_-_15982707 0.34 ENSDART00000186911
ENSDART00000181072
IKAROS family zinc finger 1 (Ikaros)
chr7_+_33314925 0.34 ENSDART00000148590
coronin, actin binding protein, 2Ba
chr15_-_32595982 0.34 ENSDART00000171808
Fras1 related extracellular matrix protein 2b
chr21_+_5993188 0.34 ENSDART00000048399
solute carrier family 4 (sodium bicarbonate cotransporter), member 4b
chr13_-_42560662 0.34 ENSDART00000124898

chr25_-_13105310 0.33 ENSDART00000172269
sphingomyelin phosphodiesterase 3, neutral
chr1_-_59104145 0.33 ENSDART00000132495
ENSDART00000152457
si:zfos-2330d3.1
si:zfos-2330d3.7
chr22_+_696931 0.33 ENSDART00000149712
ENSDART00000009756
G protein-coupled receptor 37 like 1a
chr18_+_13203831 0.33 ENSDART00000032151
coactosin-like F-actin binding protein 1
chr15_-_12319065 0.33 ENSDART00000162973
ENSDART00000170543
FXYD domain containing ion transport regulator 6
chr22_+_11867639 0.32 ENSDART00000144677
muscle RAS oncogene homolog
chr3_-_22829710 0.32 ENSDART00000055659
cytochrome b561
chr19_-_44089509 0.32 ENSDART00000189136
RAD21 cohesin complex component b
chr1_+_20084389 0.32 ENSDART00000140263
protease, serine, 12 (neurotrypsin, motopsin)
chr16_+_12517535 0.31 ENSDART00000155407
Ras interacting protein 1
chr22_-_26323893 0.31 ENSDART00000105099
calpain 1, (mu/I) large subunit b
chr17_+_23146976 0.31 ENSDART00000114212
RAS guanyl releasing protein 3 (calcium and DAG-regulated)
chr5_-_22501663 0.31 ENSDART00000133174
si:dkey-27p18.5
chr4_-_9557186 0.31 ENSDART00000150569
SH3 and multiple ankyrin repeat domains 3b
chr3_-_57737913 0.31 ENSDART00000113309
zgc:112492
chr9_-_32753535 0.31 ENSDART00000060006
oligodendrocyte lineage transcription factor 2
chr4_+_20263097 0.31 ENSDART00000138820
leucine-rich repeats and transmembrane domains 2a
chr15_+_34062460 0.31 ENSDART00000164654
si:dkey-30e9.6
chr18_-_15373620 0.30 ENSDART00000031752
regulatory factor X, 4
chr9_-_32604414 0.30 ENSDART00000088876
ENSDART00000166502
SATB homeobox 2
chr9_+_25832329 0.30 ENSDART00000130059
zinc finger E-box binding homeobox 2a
chr7_+_54617060 0.30 ENSDART00000158898
fibroblast growth factor 4
chr9_-_12736089 0.30 ENSDART00000088042
myosin X-like 3
chr12_+_14676349 0.30 ENSDART00000143401
beclin 1, autophagy related
chr10_-_20637098 0.30 ENSDART00000080391
shadow of prion protein 2
chr1_+_59073436 0.30 ENSDART00000161642
si:zfos-2330d3.3
chr18_-_15771551 0.30 ENSDART00000130931
ENSDART00000154079
si:ch211-219a15.3
chr25_-_13842618 0.30 ENSDART00000160258
mitogen-activated protein kinase 8 interacting protein 1a
chr9_-_21067971 0.30 ENSDART00000004333
T-box 15
chr22_+_5103349 0.30 ENSDART00000083474
ataxia, cerebellar, Cayman type a
chr14_-_1998501 0.30 ENSDART00000189052
protocadherin 2 gamma 5
chr5_-_37252111 0.29 ENSDART00000185110
leucine-rich repeats and calponin homology (CH) domain containing 2

Network of associatons between targets according to the STRING database.

First level regulatory network of klf12b

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 1.3 GO:0044333 Wnt signaling pathway involved in digestive tract morphogenesis(GO:0044333)
0.4 1.2 GO:0048677 axon extension involved in regeneration(GO:0048677) sprouting of injured axon(GO:0048682)
0.4 1.2 GO:0006957 complement activation, alternative pathway(GO:0006957)
0.3 1.0 GO:0002074 extraocular skeletal muscle development(GO:0002074)
0.3 0.8 GO:0014814 regulation of synaptic growth at neuromuscular junction(GO:0008582) axon regeneration at neuromuscular junction(GO:0014814) positive regulation of synaptic growth at neuromuscular junction(GO:0045887)
0.2 0.2 GO:0019323 pentose catabolic process(GO:0019323)
0.2 0.7 GO:0097264 self proteolysis(GO:0097264)
0.2 1.1 GO:0035332 positive regulation of hippo signaling(GO:0035332)
0.2 0.7 GO:0015670 carbon dioxide transport(GO:0015670)
0.2 0.7 GO:0060092 regulation of synaptic transmission, glycinergic(GO:0060092)
0.2 1.0 GO:0010801 regulation of peptidyl-threonine phosphorylation(GO:0010799) negative regulation of peptidyl-threonine phosphorylation(GO:0010801)
0.2 0.5 GO:1902746 regulation of lens fiber cell differentiation(GO:1902746)
0.1 0.6 GO:2000298 regulation of Rho-dependent protein serine/threonine kinase activity(GO:2000298)
0.1 1.1 GO:0006361 transcription initiation from RNA polymerase I promoter(GO:0006361)
0.1 2.1 GO:0001867 complement activation, lectin pathway(GO:0001867)
0.1 0.6 GO:0007508 larval development(GO:0002164) larval heart development(GO:0007508)
0.1 0.6 GO:0009052 pentose-phosphate shunt, non-oxidative branch(GO:0009052)
0.1 0.3 GO:0043416 regulation of skeletal muscle tissue regeneration(GO:0043416)
0.1 1.0 GO:0097150 neuronal stem cell population maintenance(GO:0097150)
0.1 0.4 GO:0061072 iris morphogenesis(GO:0061072)
0.1 0.5 GO:0051965 positive regulation of synapse assembly(GO:0051965)
0.1 0.8 GO:0097104 presynaptic membrane organization(GO:0097090) postsynaptic membrane assembly(GO:0097104) presynaptic membrane assembly(GO:0097105)
0.1 0.4 GO:0036371 protein localization to T-tubule(GO:0036371)
0.1 0.4 GO:0030205 dermatan sulfate metabolic process(GO:0030205)
0.1 0.2 GO:0003250 cell proliferation involved in heart valve morphogenesis(GO:0003249) regulation of cell proliferation involved in heart valve morphogenesis(GO:0003250) endocardial cell development(GO:0060958) cell proliferation involved in heart valve development(GO:2000793)
0.1 0.3 GO:0021742 abducens nucleus development(GO:0021742)
0.1 0.6 GO:0032889 regulation of vacuole fusion, non-autophagic(GO:0032889)
0.1 0.6 GO:1990402 embryonic liver development(GO:1990402)
0.1 0.5 GO:0033278 cell proliferation in midbrain(GO:0033278)
0.1 0.3 GO:0015803 branched-chain amino acid transport(GO:0015803) leucine transport(GO:0015820)
0.1 1.1 GO:0001952 regulation of cell-matrix adhesion(GO:0001952)
0.1 0.2 GO:0002369 T cell cytokine production(GO:0002369)
0.1 0.7 GO:0060012 synaptic transmission, glycinergic(GO:0060012)
0.1 0.6 GO:0060118 vestibular receptor cell differentiation(GO:0060114) vestibular receptor cell development(GO:0060118)
0.1 0.2 GO:2000434 regulation of protein neddylation(GO:2000434)
0.1 0.4 GO:0060221 retinal rod cell differentiation(GO:0060221)
0.1 0.6 GO:0035479 angioblast cell migration from lateral mesoderm to midline(GO:0035479)
0.1 0.9 GO:0042026 protein refolding(GO:0042026)
0.1 2.2 GO:0060059 embryonic retina morphogenesis in camera-type eye(GO:0060059)
0.1 0.6 GO:0006797 polyphosphate metabolic process(GO:0006797) polyphosphate catabolic process(GO:0006798)
0.1 0.5 GO:0048251 elastic fiber assembly(GO:0048251)
0.1 0.2 GO:0043455 regulation of secondary metabolic process(GO:0043455)
0.1 0.2 GO:0030213 hyaluronan biosynthetic process(GO:0030213)
0.0 0.4 GO:0035372 protein localization to microtubule(GO:0035372) protein localization to microtubule plus-end(GO:1904825)
0.0 1.8 GO:0034332 adherens junction organization(GO:0034332)
0.0 0.5 GO:0048672 positive regulation of collateral sprouting(GO:0048672)
0.0 0.3 GO:2000463 postsynaptic density assembly(GO:0097107) modulation of excitatory postsynaptic potential(GO:0098815) positive regulation of excitatory postsynaptic potential(GO:2000463)
0.0 0.9 GO:0008535 respiratory chain complex IV assembly(GO:0008535)
0.0 0.3 GO:0090243 fibroblast growth factor receptor signaling pathway involved in somitogenesis(GO:0090243)
0.0 0.4 GO:1904071 presynaptic active zone assembly(GO:1904071)
0.0 0.4 GO:0039023 pronephric duct morphogenesis(GO:0039023) nephric duct morphogenesis(GO:0072178)
0.0 0.3 GO:0090303 positive regulation of wound healing(GO:0090303)
0.0 0.7 GO:0048679 regulation of axon regeneration(GO:0048679) regulation of neuron projection regeneration(GO:0070570)
0.0 0.1 GO:0045938 positive regulation of circadian sleep/wake cycle, sleep(GO:0045938)
0.0 0.2 GO:0032287 peripheral nervous system myelin maintenance(GO:0032287)
0.0 0.1 GO:0045730 respiratory burst(GO:0045730)
0.0 0.2 GO:0090136 epithelial cell-cell adhesion(GO:0090136)
0.0 0.1 GO:0001778 plasma membrane repair(GO:0001778) chondrocyte differentiation involved in endochondral bone morphogenesis(GO:0003413) growth plate cartilage chondrocyte differentiation(GO:0003418)
0.0 0.1 GO:0048389 intermediate mesoderm development(GO:0048389)
0.0 0.3 GO:1990414 replication-born double-strand break repair via sister chromatid exchange(GO:1990414)
0.0 0.2 GO:0008584 male gonad development(GO:0008584) water homeostasis(GO:0030104)
0.0 0.1 GO:2000171 negative regulation of dendrite development(GO:2000171)
0.0 0.3 GO:0050907 detection of chemical stimulus involved in sensory perception(GO:0050907)
0.0 0.5 GO:0098962 regulation of postsynaptic neurotransmitter receptor activity(GO:0098962)
0.0 0.5 GO:0010811 positive regulation of cell-substrate adhesion(GO:0010811)
0.0 0.4 GO:0019233 sensory perception of pain(GO:0019233)
0.0 0.2 GO:0032218 riboflavin transport(GO:0032218)
0.0 0.4 GO:0001964 startle response(GO:0001964)
0.0 0.3 GO:0000305 response to superoxide(GO:0000303) response to oxygen radical(GO:0000305) removal of superoxide radicals(GO:0019430) cellular response to oxygen radical(GO:0071450) cellular response to superoxide(GO:0071451) cellular oxidant detoxification(GO:0098869) cellular detoxification(GO:1990748)
0.0 0.4 GO:0031100 organ regeneration(GO:0031100)
0.0 0.9 GO:1903670 regulation of sprouting angiogenesis(GO:1903670)
0.0 0.4 GO:0042982 amyloid precursor protein metabolic process(GO:0042982)
0.0 0.5 GO:0060038 cardiac muscle cell proliferation(GO:0060038)
0.0 0.2 GO:0002551 mast cell chemotaxis(GO:0002551) regulation of mast cell chemotaxis(GO:0060753) positive regulation of mast cell chemotaxis(GO:0060754) mast cell migration(GO:0097531)
0.0 0.9 GO:0030199 collagen fibril organization(GO:0030199)
0.0 0.2 GO:0007084 mitotic nuclear envelope reassembly(GO:0007084)
0.0 1.2 GO:0010842 retina layer formation(GO:0010842)
0.0 0.3 GO:0061300 cerebellum vasculature development(GO:0061300)
0.0 0.5 GO:0097320 membrane tubulation(GO:0097320)
0.0 0.1 GO:0090245 axis elongation involved in somitogenesis(GO:0090245)
0.0 0.2 GO:0051877 pigment granule aggregation in cell center(GO:0051877)
0.0 0.1 GO:2000812 regulation of barbed-end actin filament capping(GO:2000812)
0.0 0.5 GO:0000027 ribosomal large subunit assembly(GO:0000027)
0.0 0.6 GO:0000413 protein peptidyl-prolyl isomerization(GO:0000413)
0.0 0.1 GO:0061298 retina vasculature development in camera-type eye(GO:0061298)
0.0 0.4 GO:0048026 positive regulation of mRNA splicing, via spliceosome(GO:0048026)
0.0 0.3 GO:0033077 T cell differentiation in thymus(GO:0033077) thymocyte aggregation(GO:0071594)
0.0 0.1 GO:0031174 lifelong otolith mineralization(GO:0031174)
0.0 0.6 GO:0003323 type B pancreatic cell development(GO:0003323)
0.0 0.3 GO:1900107 regulation of nodal signaling pathway(GO:1900107)
0.0 0.1 GO:0021523 somatic motor neuron differentiation(GO:0021523)
0.0 0.1 GO:0034164 regulation of toll-like receptor 9 signaling pathway(GO:0034163) negative regulation of toll-like receptor 9 signaling pathway(GO:0034164)
0.0 0.2 GO:0061337 cardiac conduction(GO:0061337)
0.0 0.2 GO:0035970 peptidyl-threonine dephosphorylation(GO:0035970)
0.0 0.6 GO:0007416 synapse assembly(GO:0007416)
0.0 0.1 GO:0006543 glutamate biosynthetic process(GO:0006537) glutamine catabolic process(GO:0006543)
0.0 0.3 GO:0042407 cristae formation(GO:0042407)
0.0 0.6 GO:0060840 artery development(GO:0060840)
0.0 0.4 GO:0048013 ephrin receptor signaling pathway(GO:0048013)
0.0 0.2 GO:0034394 protein localization to cell surface(GO:0034394)
0.0 0.4 GO:0021952 central nervous system projection neuron axonogenesis(GO:0021952)
0.0 0.3 GO:0007418 ventral midline development(GO:0007418)
0.0 0.4 GO:0085029 extracellular matrix assembly(GO:0085029)
0.0 0.2 GO:0001992 regulation of systemic arterial blood pressure by vasopressin(GO:0001992)
0.0 0.4 GO:0039020 pronephric nephron tubule development(GO:0039020)
0.0 0.2 GO:0070262 peptidyl-serine dephosphorylation(GO:0070262)
0.0 0.3 GO:0015701 bicarbonate transport(GO:0015701)
0.0 1.0 GO:0050919 negative chemotaxis(GO:0050919)
0.0 0.7 GO:0071391 cellular response to estrogen stimulus(GO:0071391)
0.0 0.4 GO:0032526 response to retinoic acid(GO:0032526)
0.0 0.1 GO:0072337 modified amino acid transport(GO:0072337)
0.0 0.1 GO:0045580 regulation of T cell differentiation(GO:0045580)
0.0 0.1 GO:0070979 protein K11-linked ubiquitination(GO:0070979)
0.0 2.3 GO:0007156 homophilic cell adhesion via plasma membrane adhesion molecules(GO:0007156)
0.0 0.7 GO:0046328 regulation of JNK cascade(GO:0046328)
0.0 0.4 GO:0050768 negative regulation of neurogenesis(GO:0050768)
0.0 0.1 GO:0006048 UDP-N-acetylglucosamine biosynthetic process(GO:0006048)
0.0 0.3 GO:0019835 cytolysis(GO:0019835)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 2.2 GO:0016533 cyclin-dependent protein kinase 5 holoenzyme complex(GO:0016533)
0.2 0.5 GO:0060077 inhibitory synapse(GO:0060077)
0.1 0.5 GO:0033181 plasma membrane proton-transporting V-type ATPase complex(GO:0033181)
0.1 0.6 GO:0000015 phosphopyruvate hydratase complex(GO:0000015)
0.1 0.3 GO:0016460 myosin II complex(GO:0016460)
0.1 0.3 GO:0034271 phosphatidylinositol 3-kinase complex, class III, type I(GO:0034271) phosphatidylinositol 3-kinase complex, class III, type II(GO:0034272)
0.1 0.3 GO:0030314 junctional membrane complex(GO:0030314)
0.1 0.3 GO:0043083 synaptic cleft(GO:0043083)
0.0 0.2 GO:0043034 costamere(GO:0043034)
0.0 0.3 GO:0034990 nuclear cohesin complex(GO:0000798) mitotic cohesin complex(GO:0030892) nuclear mitotic cohesin complex(GO:0034990) nuclear meiotic cohesin complex(GO:0034991)
0.0 0.4 GO:0098982 GABA-ergic synapse(GO:0098982)
0.0 0.4 GO:0090533 sodium:potassium-exchanging ATPase complex(GO:0005890) cation-transporting ATPase complex(GO:0090533)
0.0 3.1 GO:0005581 collagen trimer(GO:0005581)
0.0 1.6 GO:0016342 catenin complex(GO:0016342)
0.0 0.1 GO:0060171 stereocilium membrane(GO:0060171)
0.0 0.2 GO:0034464 BBSome(GO:0034464)
0.0 1.1 GO:0044853 caveola(GO:0005901) plasma membrane raft(GO:0044853)
0.0 0.4 GO:0030315 T-tubule(GO:0030315)
0.0 0.1 GO:0071540 eukaryotic translation initiation factor 3 complex, eIF3e(GO:0071540)
0.0 0.2 GO:0032783 ELL-EAF complex(GO:0032783)
0.0 0.3 GO:0061617 MICOS complex(GO:0061617)
0.0 0.3 GO:0033270 paranode region of axon(GO:0033270) juxtaparanode region of axon(GO:0044224)
0.0 0.1 GO:0005853 eukaryotic translation elongation factor 1 complex(GO:0005853)
0.0 0.3 GO:0005640 nuclear outer membrane(GO:0005640)
0.0 0.4 GO:0035371 microtubule plus-end(GO:0035371)
0.0 0.5 GO:0098978 glutamatergic synapse(GO:0098978)
0.0 0.2 GO:0017119 Golgi transport complex(GO:0017119)
0.0 0.1 GO:0043020 NADPH oxidase complex(GO:0043020)
0.0 0.4 GO:0005791 rough endoplasmic reticulum(GO:0005791)
0.0 0.3 GO:0001917 photoreceptor inner segment(GO:0001917)
0.0 1.4 GO:0005882 intermediate filament(GO:0005882)
0.0 0.9 GO:0005604 basement membrane(GO:0005604)
0.0 0.1 GO:0030670 phagocytic vesicle membrane(GO:0030670)
0.0 0.2 GO:0008250 oligosaccharyltransferase complex(GO:0008250)
0.0 2.8 GO:0031012 extracellular matrix(GO:0031012)
0.0 0.5 GO:0030864 cortical actin cytoskeleton(GO:0030864)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.1 GO:0042134 rRNA primary transcript binding(GO:0042134)
0.2 0.7 GO:1990430 extracellular matrix protein binding(GO:1990430)
0.2 0.5 GO:0033130 acetylcholine receptor binding(GO:0033130)
0.2 2.2 GO:0061575 cyclin-dependent protein serine/threonine kinase activator activity(GO:0061575)
0.1 1.0 GO:0070888 E-box binding(GO:0070888)
0.1 0.5 GO:0070052 collagen V binding(GO:0070052)
0.1 0.3 GO:0000293 ferric-chelate reductase activity(GO:0000293)
0.1 0.6 GO:0016744 transferase activity, transferring aldehyde or ketonic groups(GO:0016744)
0.1 0.4 GO:0031769 glucagon receptor binding(GO:0031769)
0.1 1.2 GO:0038191 neuropilin binding(GO:0038191)
0.1 0.7 GO:0016934 extracellular-glycine-gated ion channel activity(GO:0016933) extracellular-glycine-gated chloride channel activity(GO:0016934)
0.1 0.4 GO:0047757 chondroitin-glucuronate 5-epimerase activity(GO:0047757)
0.1 0.4 GO:0008097 5S rRNA binding(GO:0008097)
0.1 0.6 GO:0004634 phosphopyruvate hydratase activity(GO:0004634)
0.1 1.0 GO:0005504 fatty acid binding(GO:0005504)
0.1 0.3 GO:0032034 myosin head/neck binding(GO:0032028) myosin II head/neck binding(GO:0032034) myosin II heavy chain binding(GO:0032038)
0.1 0.9 GO:0044183 protein binding involved in protein folding(GO:0044183)
0.1 0.2 GO:0043183 vascular endothelial growth factor receptor 1 binding(GO:0043183)
0.1 0.5 GO:0016941 natriuretic peptide receptor activity(GO:0016941)
0.1 0.6 GO:0004309 exopolyphosphatase activity(GO:0004309)
0.1 0.3 GO:0015193 L-proline transmembrane transporter activity(GO:0015193)
0.1 0.5 GO:0016936 galactoside binding(GO:0016936)
0.1 0.2 GO:0050211 procollagen galactosyltransferase activity(GO:0050211)
0.1 1.6 GO:0004198 calcium-dependent cysteine-type endopeptidase activity(GO:0004198)
0.1 0.7 GO:0015187 glycine transmembrane transporter activity(GO:0015187)
0.0 1.7 GO:0003823 antigen binding(GO:0003823)
0.0 0.4 GO:0008511 sodium:potassium:chloride symporter activity(GO:0008511)
0.0 0.3 GO:0030160 GKAP/Homer scaffold activity(GO:0030160)
0.0 0.4 GO:0044323 retinoic acid-responsive element binding(GO:0044323)
0.0 0.2 GO:0070004 cysteine-type exopeptidase activity(GO:0070004)
0.0 0.4 GO:0004985 opioid receptor activity(GO:0004985)
0.0 0.5 GO:0005165 nerve growth factor receptor binding(GO:0005163) neurotrophin receptor binding(GO:0005165)
0.0 0.3 GO:0008379 thioredoxin peroxidase activity(GO:0008379)
0.0 1.3 GO:0017147 Wnt-protein binding(GO:0017147)
0.0 0.8 GO:0042043 neurexin family protein binding(GO:0042043)
0.0 0.1 GO:0002151 G-quadruplex RNA binding(GO:0002151)
0.0 0.1 GO:0070324 thyroid hormone binding(GO:0070324)
0.0 0.2 GO:0032217 riboflavin transporter activity(GO:0032217)
0.0 0.1 GO:0070548 L-glutamine aminotransferase activity(GO:0070548)
0.0 0.2 GO:0004359 glutaminase activity(GO:0004359)
0.0 0.1 GO:0051800 inositol-1,3,4,5-tetrakisphosphate 3-phosphatase activity(GO:0051717) phosphatidylinositol-3,4-bisphosphate 3-phosphatase activity(GO:0051800)
0.0 0.4 GO:0098882 structural constituent of presynaptic active zone(GO:0098882)
0.0 0.3 GO:0008510 sodium:bicarbonate symporter activity(GO:0008510)
0.0 0.3 GO:0004767 sphingomyelin phosphodiesterase activity(GO:0004767)
0.0 1.4 GO:0005200 structural constituent of cytoskeleton(GO:0005200)
0.0 0.2 GO:0031779 melanocortin receptor binding(GO:0031779)
0.0 0.4 GO:0070001 aspartic-type endopeptidase activity(GO:0004190) aspartic-type peptidase activity(GO:0070001)
0.0 0.2 GO:0004459 L-lactate dehydrogenase activity(GO:0004459)
0.0 2.1 GO:0008201 heparin binding(GO:0008201)
0.0 0.4 GO:0046875 ephrin receptor binding(GO:0046875)
0.0 1.0 GO:0003755 peptidyl-prolyl cis-trans isomerase activity(GO:0003755)
0.0 0.6 GO:0004089 carbonate dehydratase activity(GO:0004089)
0.0 0.3 GO:0005080 protein kinase C binding(GO:0005080)
0.0 0.2 GO:0008330 protein tyrosine/threonine phosphatase activity(GO:0008330)
0.0 0.4 GO:0001671 ATPase activator activity(GO:0001671)
0.0 0.6 GO:0051020 GTPase binding(GO:0051020)
0.0 0.2 GO:0045159 myosin II binding(GO:0045159)
0.0 0.1 GO:0001222 transcription corepressor binding(GO:0001222)
0.0 0.2 GO:0005000 vasopressin receptor activity(GO:0005000)
0.0 0.6 GO:0031624 ubiquitin conjugating enzyme binding(GO:0031624)
0.0 1.9 GO:0005201 extracellular matrix structural constituent(GO:0005201)
0.0 0.5 GO:0030165 PDZ domain binding(GO:0030165)
0.0 0.0 GO:0003831 beta-N-acetylglucosaminylglycopeptide beta-1,4-galactosyltransferase activity(GO:0003831)
0.0 0.2 GO:0008266 poly(U) RNA binding(GO:0008266)
0.0 0.2 GO:0051721 protein phosphatase 2A binding(GO:0051721)
0.0 0.3 GO:0017080 sodium channel regulator activity(GO:0017080)
0.0 0.2 GO:0016864 protein disulfide isomerase activity(GO:0003756) intramolecular oxidoreductase activity, transposing S-S bonds(GO:0016864)
0.0 1.1 GO:0045296 cadherin binding(GO:0045296)
0.0 0.2 GO:0051371 muscle alpha-actinin binding(GO:0051371) alpha-actinin binding(GO:0051393)
0.0 0.1 GO:0004383 guanylate cyclase activity(GO:0004383)
0.0 0.3 GO:0022848 acetylcholine-gated cation channel activity(GO:0022848)
0.0 0.0 GO:0070016 armadillo repeat domain binding(GO:0070016)
0.0 0.3 GO:0005104 fibroblast growth factor receptor binding(GO:0005104)
0.0 0.4 GO:0005184 neuropeptide hormone activity(GO:0005184)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.8 PID INTEGRIN A9B1 PATHWAY Alpha9 beta1 integrin signaling events
0.0 1.2 NABA PROTEOGLYCANS Genes encoding proteoglycans
0.0 0.4 PID SYNDECAN 3 PATHWAY Syndecan-3-mediated signaling events
0.0 0.4 PID CONE PATHWAY Visual signal transduction: Cones
0.0 0.4 PID RAC1 REG PATHWAY Regulation of RAC1 activity
0.0 1.6 NABA ECM AFFILIATED Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.0 0.4 ST MYOCYTE AD PATHWAY Myocyte Adrenergic Pathway is a specific case of the generalized Adrenergic Pathway.
0.0 0.8 PID HES HEY PATHWAY Notch-mediated HES/HEY network
0.0 0.5 PID CERAMIDE PATHWAY Ceramide signaling pathway
0.0 0.4 PID INTEGRIN3 PATHWAY Beta3 integrin cell surface interactions
0.0 0.3 PID NFAT TFPATHWAY Calcineurin-regulated NFAT-dependent transcription in lymphocytes
0.0 0.2 PID ERB GENOMIC PATHWAY Validated nuclear estrogen receptor beta network
0.0 2.0 NABA SECRETED FACTORS Genes encoding secreted soluble factors
0.0 0.1 PID RAC1 PATHWAY RAC1 signaling pathway
0.0 1.5 NABA ECM GLYCOPROTEINS Genes encoding structural ECM glycoproteins

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.6 REACTOME REGULATION OF COMPLEMENT CASCADE Genes involved in Regulation of Complement cascade
0.1 1.2 REACTOME INITIAL TRIGGERING OF COMPLEMENT Genes involved in Initial triggering of complement
0.1 1.5 REACTOME POST CHAPERONIN TUBULIN FOLDING PATHWAY Genes involved in Post-chaperonin tubulin folding pathway
0.1 0.4 REACTOME DOPAMINE NEUROTRANSMITTER RELEASE CYCLE Genes involved in Dopamine Neurotransmitter Release Cycle
0.1 0.8 REACTOME KERATAN SULFATE DEGRADATION Genes involved in Keratan sulfate degradation
0.1 0.9 REACTOME NA CL DEPENDENT NEUROTRANSMITTER TRANSPORTERS Genes involved in Na+/Cl- dependent neurotransmitter transporters
0.1 0.3 REACTOME SIGNALING BY ACTIVATED POINT MUTANTS OF FGFR1 Genes involved in Signaling by activated point mutants of FGFR1
0.1 0.7 REACTOME PURINE RIBONUCLEOSIDE MONOPHOSPHATE BIOSYNTHESIS Genes involved in Purine ribonucleoside monophosphate biosynthesis
0.0 1.5 REACTOME NCAM1 INTERACTIONS Genes involved in NCAM1 interactions
0.0 0.1 REACTOME CREB PHOSPHORYLATION THROUGH THE ACTIVATION OF CAMKII Genes involved in CREB phosphorylation through the activation of CaMKII
0.0 0.9 REACTOME ADHERENS JUNCTIONS INTERACTIONS Genes involved in Adherens junctions interactions
0.0 1.0 REACTOME MYOGENESIS Genes involved in Myogenesis
0.0 0.3 REACTOME PRESYNAPTIC NICOTINIC ACETYLCHOLINE RECEPTORS Genes involved in Presynaptic nicotinic acetylcholine receptors
0.0 0.2 REACTOME RECEPTOR LIGAND BINDING INITIATES THE SECOND PROTEOLYTIC CLEAVAGE OF NOTCH RECEPTOR Genes involved in Receptor-ligand binding initiates the second proteolytic cleavage of Notch receptor
0.0 0.4 REACTOME CALNEXIN CALRETICULIN CYCLE Genes involved in Calnexin/calreticulin cycle
0.0 0.2 REACTOME HYALURONAN METABOLISM Genes involved in Hyaluronan metabolism
0.0 0.2 REACTOME RNA POL III CHAIN ELONGATION Genes involved in RNA Polymerase III Chain Elongation
0.0 0.1 REACTOME SYNTHESIS OF BILE ACIDS AND BILE SALTS VIA 24 HYDROXYCHOLESTEROL Genes involved in Synthesis of bile acids and bile salts via 24-hydroxycholesterol
0.0 0.3 REACTOME G PROTEIN ACTIVATION Genes involved in G-protein activation
0.0 0.4 REACTOME GLYCOSPHINGOLIPID METABOLISM Genes involved in Glycosphingolipid metabolism