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PRJNA195909:zebrafish embryo and larva development

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Results for klf12a

Z-value: 0.60

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Transcription factors associated with klf12a

Gene Symbol Gene ID Gene Info
ENSDARG00000015312 Kruppel-like factor 12a
ENSDARG00000115152 Kruppel-like factor 12a

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
klf12adr11_v1_chr1_+_34496855_344968550.964.7e-05Click!

Activity profile of klf12a motif

Sorted Z-values of klf12a motif

Promoter Log-likelihood Transcript Gene Gene Info
chr8_+_23213320 1.04 ENSDART00000032996
ENSDART00000137536
pancreatic progenitor cell differentiation and proliferation factor a
chr13_+_28417297 0.97 ENSDART00000043658
solute carrier family 2 (facilitated glucose transporter), member 15a
chr11_-_11301283 0.80 ENSDART00000113311
ENSDART00000180466
collagen, type IX, alpha 1a
chr1_-_59176949 0.70 ENSDART00000128742

chr10_+_15777064 0.69 ENSDART00000114483
amyloid beta (A4) precursor protein-binding, family A, member 1b
chr3_+_27027781 0.65 ENSDART00000065495
epithelial membrane protein 2
chr7_+_23907692 0.61 ENSDART00000045479
synaptotagmin IV
chr15_+_47161917 0.61 ENSDART00000167860
growth associated protein 43
chr23_-_17470146 0.59 ENSDART00000002398
tripartite motif containing 101
chr4_+_17417111 0.59 ENSDART00000056005
achaete-scute family bHLH transcription factor 1a
chr25_+_3358701 0.57 ENSDART00000104877
coiled-coil-helix-coiled-coil-helix domain containing 3b
chr12_+_42436328 0.57 ENSDART00000167324
early B cell factor 3a
chr2_+_30916188 0.56 ENSDART00000137012
myomesin 1a (skelemin)
chr9_-_296169 0.56 ENSDART00000165228
kinesin family member 5A, a
chr2_+_59015878 0.53 ENSDART00000148816
ENSDART00000122795
si:ch1073-391i24.1
chr9_+_42095220 0.51 ENSDART00000148317
ENSDART00000134431
poly(rC) binding protein 3
chr16_-_17197546 0.50 ENSDART00000139939
ENSDART00000135146
ENSDART00000063800
ENSDART00000163606
glyceraldehyde-3-phosphate dehydrogenase
chr10_+_19554604 0.49 ENSDART00000063806
ATPase H+ transporting V1 subunit B2
chr8_-_4618653 0.49 ENSDART00000025535
septin 5a
chr25_-_25736958 0.47 ENSDART00000166308
calcium and integrin binding family member 2
chr5_+_37056818 0.47 ENSDART00000036760
tubulin polymerization-promoting protein family member 2
chr25_+_34013093 0.47 ENSDART00000011967
annexin A2a
chr11_-_25384213 0.47 ENSDART00000103650
v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog Bb
chr15_-_19250543 0.46 ENSDART00000092705
ENSDART00000138895
immunoglobulin superfamily, member 9Ba
chr20_+_20672163 0.46 ENSDART00000027758
reticulon 1b
chr7_+_30867008 0.45 ENSDART00000193106
amyloid beta (A4) precursor protein-binding, family A, member 2b
chr13_+_36764715 0.45 ENSDART00000111832
ENSDART00000085230
atlastin GTPase 1
chr9_+_1654284 0.44 ENSDART00000062854
nuclear factor, erythroid 2-like 2a
chr18_+_44649804 0.44 ENSDART00000059063
EH-domain containing 2b
chr19_+_48111285 0.44 ENSDART00000169420
NME/NM23 nucleoside diphosphate kinase 2b, tandem duplicate 2
chr2_+_30379650 0.43 ENSDART00000129542
cysteine-rich secretory protein LCCL domain containing 1b
chr2_-_2020044 0.43 ENSDART00000024135
tubulin, beta 2A class IIa
chr17_+_51764310 0.43 ENSDART00000157171
si:ch211-168d23.3
chr15_+_17752928 0.42 ENSDART00000155314
si:ch211-213d14.2
chr1_-_51734524 0.41 ENSDART00000109640
ENSDART00000122628
JunB proto-oncogene, AP-1 transcription factor subunit a
chr4_-_9852318 0.41 ENSDART00000080702
glycosyltransferase 8 domain containing 2
chr17_-_4318393 0.40 ENSDART00000167995
ENSDART00000153824
N-ethylmaleimide-sensitive factor attachment protein, beta a
chr20_-_53366137 0.39 ENSDART00000146001
WAS protein family, member 1
chr10_-_17988779 0.39 ENSDART00000132206
ENSDART00000144841
si:dkey-242g16.2
chr6_-_18976168 0.39 ENSDART00000170039
septin 9b
chr5_+_67812062 0.39 ENSDART00000158611
zgc:175280
chr23_+_10146542 0.38 ENSDART00000048073
zgc:171775
chr6_-_57938043 0.38 ENSDART00000171073
TOX high mobility group box family member 2
chr6_-_17849786 0.37 ENSDART00000172709
regulatory associated protein of MTOR, complex 1
chr10_+_1668106 0.37 ENSDART00000142278
small G protein signaling modulator 1b
chr4_-_5597802 0.37 ENSDART00000136229
vascular endothelial growth factor Ab
chr10_+_15777258 0.36 ENSDART00000140511
amyloid beta (A4) precursor protein-binding, family A, member 1b
chr18_-_3166726 0.36 ENSDART00000165002
aquaporin 11
chr23_+_44732863 0.36 ENSDART00000160044
ENSDART00000172268
ATPase Na+/K+ transporting subunit beta 2a
chr1_-_46663997 0.35 ENSDART00000134450
emopamil binding protein-like
chr19_-_2421793 0.35 ENSDART00000180238
transmembrane protein 196
chr1_-_18803919 0.35 ENSDART00000020970
phosphoglucomutase 2
chr19_-_42391383 0.35 ENSDART00000110075
ENSDART00000087002
pleckstrin homology domain containing, family O member 1a
chr13_+_4405282 0.34 ENSDART00000148280
proline rich 18
chr5_-_9824908 0.34 ENSDART00000169698
zgc:158343
chr5_+_38263240 0.33 ENSDART00000051231
guanine nucleotide binding protein (G protein), beta polypeptide 2
chr16_-_12316979 0.33 ENSDART00000182392
transient receptor potential cation channel, subfamily V, member 6
chr9_-_1984604 0.33 ENSDART00000082339
homeobox D12a
chr21_+_1382078 0.33 ENSDART00000188463
transcription factor 4
chr19_-_31372896 0.32 ENSDART00000046609
scinderin
chr3_-_36612877 0.32 ENSDART00000167164
si:dkeyp-72e1.7
chr1_+_9004719 0.31 ENSDART00000006211
ENSDART00000137211
protein kinase C, beta a
chr5_+_36850650 0.31 ENSDART00000051186
non-specific cytotoxic cell receptor protein 1
chr6_+_16031189 0.31 ENSDART00000015333
gastrulation brain homeobox 2
chr19_+_47290287 0.30 ENSDART00000078382
thiopurine S-methyltransferase, tandem duplicate 1
chr19_-_2420990 0.30 ENSDART00000181498
transmembrane protein 196
chr15_+_24388782 0.30 ENSDART00000191661
ENSDART00000179995
ENSDART00000111226
seizure related 6 homolog b
chr20_+_572037 0.29 ENSDART00000028062
ENSDART00000152736
ENSDART00000031759
ENSDART00000162198
SET and MYND domain containing 2b
chr21_+_6197223 0.29 ENSDART00000147716
si:dkey-93m18.3
chr18_-_46258612 0.29 ENSDART00000153930
si:dkey-244a7.1
chr2_+_413370 0.29 ENSDART00000122138
myosin light chain kinase family, member 4a
chr6_+_59967994 0.28 ENSDART00000050457
zgc:65895
chr7_-_58729894 0.27 ENSDART00000149347
coiled-coil-helix-coiled-coil-helix domain containing 7
chr13_-_36391496 0.27 ENSDART00000100217
ENSDART00000140243
actinin, alpha 1
chr17_-_43466317 0.26 ENSDART00000155313
heat shock protein 4 like
chr6_-_16406210 0.26 ENSDART00000012023
Fas apoptotic inhibitory molecule b
chr22_+_10757848 0.25 ENSDART00000145551
transmembrane protease, serine 9
chr12_+_47909026 0.25 ENSDART00000192472
thymus, brain and testes associated
chr17_+_25332711 0.25 ENSDART00000082319
transmembrane protein 54a
chr17_+_8925232 0.25 ENSDART00000036668
proteasome 26S subunit, ATPase 1a
chr18_+_21122818 0.25 ENSDART00000060015
ENSDART00000060184
choline kinase alpha
chr6_+_16406723 0.25 ENSDART00000040035
coiled-coil domain containing 80 like 1
chr21_+_30549512 0.25 ENSDART00000132831
RAB38c, member of RAS oncogene family
chr14_+_4151379 0.25 ENSDART00000160431
dehydrogenase/reductase (SDR family) member 13 like 1
chr8_+_29962635 0.25 ENSDART00000007640
patched 1
chr24_-_29777413 0.25 ENSDART00000087724
wu:fj05g07
chr2_+_23222939 0.25 ENSDART00000026800
kinesin-associated protein 3b
chr9_+_34425736 0.24 ENSDART00000135147
si:ch211-218d20.15
chr6_+_23122789 0.24 ENSDART00000049226
ENSDART00000067560
acyl-CoA oxidase 1, palmitoyl
chr14_+_7048930 0.23 ENSDART00000109138
heparin-binding EGF-like growth factor a
chr10_+_35422802 0.23 ENSDART00000147303
HERV-H LTR-associating 2a, tandem duplicate 1
chr11_-_42554290 0.23 ENSDART00000130573
ATPase H+ transporting accessory protein 1 like a
chr12_+_13282797 0.23 ENSDART00000137757
ENSDART00000152397
interferon regulatory factor 9
chr13_-_30028103 0.23 ENSDART00000183889
stearoyl-CoA desaturase b
chr16_-_42523744 0.23 ENSDART00000017185
T-box 20
chr3_-_22829710 0.23 ENSDART00000055659
cytochrome b561
chr25_-_31423493 0.23 ENSDART00000027661
myogenic differentiation 1
chr5_-_46273938 0.23 ENSDART00000080033
si:ch211-130m23.3
chr25_-_11088839 0.22 ENSDART00000154748
synaptic vesicle glycoprotein 2Bb
chr19_+_27479563 0.22 ENSDART00000049368
ENSDART00000185426
alpha tubulin acetyltransferase 1
chr10_+_39952995 0.22 ENSDART00000183077

chr6_-_52156427 0.22 ENSDART00000082821
regulating synaptic membrane exocytosis 4
chr11_+_45287541 0.22 ENSDART00000165321
ENSDART00000173116
pyrroline-5-carboxylate reductase 1b
chr21_+_11415224 0.22 ENSDART00000049036
zgc:92275
chr22_-_6968756 0.21 ENSDART00000136636
fibroblast growth factor receptor 1b, like
chr10_-_42131408 0.21 ENSDART00000076693
STAM binding protein a
chr2_+_54798689 0.21 ENSDART00000183426
twisted gastrulation BMP signaling modulator 1a
chr18_-_15467446 0.21 ENSDART00000187847
endonuclease, polyU-specific C
chr23_+_31107685 0.20 ENSDART00000103448
T-box 18
chr8_+_52637507 0.20 ENSDART00000163830
si:dkey-90l8.3
chr14_-_24391424 0.19 ENSDART00000113376
ENSDART00000126894
family with sequence similarity 13, member B
chr4_-_11810799 0.19 ENSDART00000014153
cytochrome b5 reductase 3
chr19_+_27479838 0.19 ENSDART00000103922
alpha tubulin acetyltransferase 1
chr19_+_47299212 0.19 ENSDART00000158262
thiopurine S-methyltransferase, tandem duplicate 1
chr25_+_6122823 0.19 ENSDART00000191824
ENSDART00000067514
RNA binding protein with multiple splicing 2a
chr14_+_33882973 0.19 ENSDART00000019396
chloride intracellular channel 2
chr18_+_38191346 0.19 ENSDART00000052703
nucleobindin 2b
chr19_+_8144556 0.19 ENSDART00000027274
ENSDART00000147218
ephrin-A3a
chr19_+_31061718 0.19 ENSDART00000145971
sclerostin domain containing 1b
chr18_-_14677936 0.19 ENSDART00000111995
si:dkey-238o13.4
chr5_-_33274645 0.18 ENSDART00000188584
kynurenine aminotransferase 1
chr3_+_36284986 0.18 ENSDART00000059533
WD repeat domain, phosphoinositide interacting 1
chr22_+_34430310 0.18 ENSDART00000109860
adhesion molecule with Ig-like domain 3
chr7_+_38762043 0.18 ENSDART00000036461
Rho GTPase activating protein 1
chr21_+_30937690 0.18 ENSDART00000022562
ras homolog family member Gb
chr13_+_35339182 0.18 ENSDART00000019323
jagged 1b
chr22_-_881080 0.18 ENSDART00000185489
choline/ethanolamine phosphotransferase 1b
chr23_-_31645760 0.18 ENSDART00000035031
serum/glucocorticoid regulated kinase 1
chr11_-_23458792 0.18 ENSDART00000032844
pleckstrin homology domain containing, family A member 6
chr3_-_32541033 0.17 ENSDART00000151476
ENSDART00000055324
reticulocalbin 3, EF-hand calcium binding domain
chr3_+_14388010 0.17 ENSDART00000171726
ENSDART00000165452
transmembrane protein 56b
chr20_-_43786515 0.16 ENSDART00000004601
lysosomal protein transmembrane 4 alpha
chr19_+_22216778 0.16 ENSDART00000052521
nuclear factor of activated T cells 1
chr24_-_14712427 0.16 ENSDART00000176316
junctophilin 1a
chr10_+_33382858 0.16 ENSDART00000063662
malate dehydrogenase 2, NAD (mitochondrial)
chr20_-_5254610 0.16 ENSDART00000057699
cytochrome P450, family 46, subfamily A, polypeptide 1, tandem duplicate 2
chr11_+_25064519 0.16 ENSDART00000016181
ndrg family member 3a
chr16_-_44399335 0.16 ENSDART00000165058
regulating synaptic membrane exocytosis 2a
chr24_-_21923930 0.16 ENSDART00000131944
transgelin 3b
chr2_+_25657958 0.16 ENSDART00000161407
TRAF2 and NCK interacting kinase a
chr2_+_25560556 0.16 ENSDART00000133623
phospholipase D1a
chr6_+_34512313 0.16 ENSDART00000102554
low density lipoprotein receptor-related protein 8, apolipoprotein e receptor
chr25_+_7492663 0.16 ENSDART00000166496
catalase
chr4_-_9557186 0.16 ENSDART00000150569
SH3 and multiple ankyrin repeat domains 3b
chr17_+_53250802 0.16 ENSDART00000143819
vasohibin 1
chr6_+_34511886 0.16 ENSDART00000179450
low density lipoprotein receptor-related protein 8, apolipoprotein e receptor
chr3_-_47876427 0.15 ENSDART00000180844
ENSDART00000124480
adhesion G protein-coupled receptor L1a
chr14_+_33264303 0.15 ENSDART00000130680
ENSDART00000075187
PDZ domain containing 11
chr7_-_6592142 0.15 ENSDART00000160137
potassium inwardly-rectifying channel, subfamily J, member 10a
chr20_-_46554440 0.15 ENSDART00000043298
ENSDART00000060680
v-fos FBJ murine osteosarcoma viral oncogene homolog Ab
chr21_+_25236297 0.15 ENSDART00000112783
transmembrane protein 45B
chr4_-_11810365 0.15 ENSDART00000150529
cytochrome b5 reductase 3
chr22_-_38224315 0.14 ENSDART00000165430
ENSDART00000140968
Hermansky-Pudlak syndrome 3
chr5_-_2689753 0.14 ENSDART00000172699
guanine nucleotide binding protein (G protein), gamma 10
chr12_+_48815988 0.14 ENSDART00000149089
annexin A11b
chr22_-_29586608 0.14 ENSDART00000059869
adrenoceptor alpha 2A
chr23_-_32129569 0.14 ENSDART00000167761
ENSDART00000139569
zgc:92658
chr19_+_342094 0.14 ENSDART00000151013
ENSDART00000187622
endosulfine alpha a
chr4_+_3980247 0.14 ENSDART00000049194
G protein-coupled receptor 37b
chr23_-_17429775 0.14 ENSDART00000043076
pancreatic progenitor cell differentiation and proliferation factor b
chr14_-_2602445 0.14 ENSDART00000166910
eukaryotic translation termination factor 1a
chr5_-_50992690 0.14 ENSDART00000149553
ENSDART00000097460
ENSDART00000192021
3-hydroxy-3-methylglutaryl-CoA reductase a
chr24_-_36238054 0.14 ENSDART00000155725
transmembrane protein 241
chr2_+_25658112 0.14 ENSDART00000051234
TRAF2 and NCK interacting kinase a
chr25_+_19008497 0.14 ENSDART00000104420
SAMM50 sorting and assembly machinery component
chr3_+_22578369 0.13 ENSDART00000187695
ENSDART00000182678
ENSDART00000112270
tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2a
chr1_-_8653385 0.13 ENSDART00000193041
actin, beta 1
chr25_+_3788443 0.13 ENSDART00000189747
chitinase domain containing 1
chr13_+_16279890 0.13 ENSDART00000101775
ENSDART00000057948
annexin A11a
chr3_+_13511984 0.13 ENSDART00000158942

chr11_+_35364445 0.13 ENSDART00000125766
CaM kinase-like vesicle-associated b
chr5_-_72136548 0.13 ENSDART00000007827
sepiapterin reductase a
chr20_-_54381034 0.13 ENSDART00000136779
ectonucleoside triphosphate diphosphohydrolase 5b
chr20_-_9580446 0.13 ENSDART00000014168
zinc finger protein 36, C3H type-like 1b
chr3_+_5575313 0.13 ENSDART00000134693
ENSDART00000101807
si:ch211-106h11.3
chr7_-_18601206 0.13 ENSDART00000111636
si:ch211-119e14.2
chr3_+_19299309 0.12 ENSDART00000046297
ENSDART00000146955
low density lipoprotein receptor a
chr22_+_661711 0.12 ENSDART00000113795
E74-like factor 3 (ets domain transcription factor, epithelial-specific )
chr12_+_6391243 0.12 ENSDART00000152765
protein kinase, cGMP-dependent, type Ib
chr14_+_46410766 0.12 ENSDART00000032342
annexin A5a
chr25_-_6049339 0.12 ENSDART00000075184
sorting nexin 1a
chr14_+_12109535 0.12 ENSDART00000054620
ENSDART00000121913
potassium channel tetramerisation domain containing 12b
chr8_-_1956632 0.12 ENSDART00000131602
si:dkey-178e17.1
chr10_+_1638876 0.12 ENSDART00000184484
ENSDART00000060946
ENSDART00000181251
small G protein signaling modulator 1b
chr8_-_17167819 0.12 ENSDART00000135042
ENSDART00000143920
mitochondrial ribosomal protein S36
chr25_-_1720736 0.11 ENSDART00000097256
solute carrier family 6 member 13
chr13_+_421231 0.11 ENSDART00000188212
ENSDART00000017854
leucine-rich, glioma inactivated 1a
chr21_-_32060993 0.11 ENSDART00000131651
si:ch211-160j14.2
chr25_+_25737386 0.11 ENSDART00000108476
leucine rich repeat containing 61
chr3_+_472158 0.11 ENSDART00000134971
zgc:194659
chr10_+_4875262 0.11 ENSDART00000165942
paralemmin 2
chr1_+_42874410 0.11 ENSDART00000153506
catenin (cadherin-associated protein), alpha 2
chr24_+_41931585 0.11 ENSDART00000130310
erythrocyte membrane protein band 4.1-like 3a
chr17_-_31695217 0.11 ENSDART00000104332
ENSDART00000143090
lin-52 DREAM MuvB core complex component
chr14_+_12110020 0.11 ENSDART00000192462
potassium channel tetramerisation domain containing 12b
chr13_-_36621926 0.11 ENSDART00000057155
cyclin-dependent kinase inhibitor 3
chr5_-_68022631 0.10 ENSDART00000143199
WAS protein family, member 3a
chr11_+_29790626 0.10 ENSDART00000067822
dynein, light chain, Tctex-type 3
chr25_+_4635355 0.10 ENSDART00000021120
protein-glucosylgalactosylhydroxylysine glucosidase
chr13_+_49175947 0.10 ENSDART00000056927
egl-9 family hypoxia-inducible factor 1a

Network of associatons between targets according to the STRING database.

First level regulatory network of klf12a

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.6 GO:0001977 renal system process involved in regulation of blood volume(GO:0001977) renal system process involved in regulation of systemic arterial blood pressure(GO:0003071) regulation of glomerular filtration(GO:0003093)
0.1 0.6 GO:0061549 sympathetic ganglion development(GO:0061549)
0.1 0.6 GO:1990535 neuron projection maintenance(GO:1990535)
0.1 0.5 GO:0007638 mechanosensory behavior(GO:0007638)
0.1 0.4 GO:0010807 regulation of synaptic vesicle priming(GO:0010807)
0.1 0.3 GO:0045023 G0 to G1 transition(GO:0045023) regulation of G0 to G1 transition(GO:0070316) negative regulation of G0 to G1 transition(GO:0070317)
0.1 0.2 GO:0002074 extraocular skeletal muscle development(GO:0002074)
0.1 0.4 GO:1902023 L-arginine import(GO:0043091) amino acid import across plasma membrane(GO:0089718) arginine import(GO:0090467) L-arginine import across plasma membrane(GO:0097638) L-arginine transport(GO:1902023) L-arginine import into cell(GO:1902765) amino acid import into cell(GO:1902837) L-arginine transmembrane transport(GO:1903400) arginine transmembrane transport(GO:1903826)
0.1 0.2 GO:0033540 fatty acid beta-oxidation using acyl-CoA oxidase(GO:0033540)
0.1 0.2 GO:1903966 monounsaturated fatty acid metabolic process(GO:1903964) monounsaturated fatty acid biosynthetic process(GO:1903966)
0.1 0.2 GO:0060043 regulation of cardiac muscle tissue growth(GO:0055021) regulation of cardiac muscle cell proliferation(GO:0060043)
0.1 0.3 GO:0048635 negative regulation of muscle organ development(GO:0048635)
0.1 0.2 GO:0007008 outer mitochondrial membrane organization(GO:0007008) protein import into mitochondrial outer membrane(GO:0045040)
0.0 0.2 GO:0032534 regulation of microvillus organization(GO:0032530) regulation of microvillus assembly(GO:0032534)
0.0 0.4 GO:0071379 cellular response to prostaglandin stimulus(GO:0071379)
0.0 0.6 GO:0016198 axon choice point recognition(GO:0016198)
0.0 0.2 GO:0051148 smooth muscle cell differentiation(GO:0051145) negative regulation of muscle cell differentiation(GO:0051148)
0.0 0.3 GO:0018026 peptidyl-lysine monomethylation(GO:0018026)
0.0 0.4 GO:0060753 mast cell chemotaxis(GO:0002551) regulation of mast cell chemotaxis(GO:0060753) positive regulation of mast cell chemotaxis(GO:0060754) mast cell migration(GO:0097531)
0.0 0.5 GO:2000601 positive regulation of actin nucleation(GO:0051127) positive regulation of Arp2/3 complex-mediated actin nucleation(GO:2000601)
0.0 0.2 GO:1903361 protein localization to basolateral plasma membrane(GO:1903361)
0.0 0.3 GO:1904861 excitatory synapse assembly(GO:1904861)
0.0 0.1 GO:0006843 mitochondrial citrate transport(GO:0006843)
0.0 0.1 GO:0071881 adenylate cyclase-inhibiting adrenergic receptor signaling pathway(GO:0071881)
0.0 0.3 GO:0021871 forebrain regionalization(GO:0021871)
0.0 0.1 GO:0002184 cytoplasmic translational termination(GO:0002184)
0.0 0.1 GO:0051823 regulation of synapse structural plasticity(GO:0051823)
0.0 0.4 GO:0046051 UTP biosynthetic process(GO:0006228) UTP metabolic process(GO:0046051)
0.0 0.2 GO:0045741 positive regulation of epidermal growth factor-activated receptor activity(GO:0045741) positive regulation of receptor activity(GO:2000273)
0.0 0.2 GO:0055129 proline biosynthetic process(GO:0006561) L-proline biosynthetic process(GO:0055129)
0.0 0.3 GO:1902041 regulation of extrinsic apoptotic signaling pathway via death domain receptors(GO:1902041) negative regulation of extrinsic apoptotic signaling pathway via death domain receptors(GO:1902042)
0.0 0.6 GO:0007007 inner mitochondrial membrane organization(GO:0007007)
0.0 0.0 GO:0032770 regulation of monooxygenase activity(GO:0032768) positive regulation of monooxygenase activity(GO:0032770)
0.0 0.1 GO:0036268 swimming(GO:0036268)
0.0 0.2 GO:0031294 lymphocyte costimulation(GO:0031294) T cell costimulation(GO:0031295)
0.0 0.1 GO:0032367 intracellular cholesterol transport(GO:0032367)
0.0 0.1 GO:0034498 early endosome to Golgi transport(GO:0034498)
0.0 1.2 GO:0031017 exocrine pancreas development(GO:0031017) exocrine system development(GO:0035272)
0.0 0.1 GO:0015919 peroxisomal membrane transport(GO:0015919) protein import into peroxisome membrane(GO:0045046)
0.0 0.4 GO:0010962 regulation of glycogen biosynthetic process(GO:0005979) regulation of glucan biosynthetic process(GO:0010962)
0.0 0.2 GO:0042574 retinal metabolic process(GO:0042574)
0.0 0.4 GO:0048791 calcium ion-regulated exocytosis of neurotransmitter(GO:0048791)
0.0 0.6 GO:0014059 dopamine secretion(GO:0014046) regulation of dopamine secretion(GO:0014059)
0.0 0.2 GO:0006108 malate metabolic process(GO:0006108)
0.0 0.4 GO:0048263 determination of dorsal identity(GO:0048263)
0.0 0.2 GO:0034497 protein localization to pre-autophagosomal structure(GO:0034497)
0.0 0.1 GO:0070292 N-acylphosphatidylethanolamine metabolic process(GO:0070292)
0.0 0.3 GO:0051764 actin crosslink formation(GO:0051764)
0.0 0.2 GO:0046337 phosphatidylethanolamine biosynthetic process(GO:0006646) phosphatidylethanolamine metabolic process(GO:0046337)
0.0 0.2 GO:0016127 cholesterol catabolic process(GO:0006707) sterol catabolic process(GO:0016127)
0.0 0.2 GO:0035306 positive regulation of dephosphorylation(GO:0035306) positive regulation of protein dephosphorylation(GO:0035307)
0.0 0.5 GO:0050821 protein stabilization(GO:0050821)
0.0 0.2 GO:0070189 kynurenine metabolic process(GO:0070189)
0.0 0.2 GO:0032094 response to food(GO:0032094)
0.0 0.3 GO:0006516 glycoprotein catabolic process(GO:0006516)
0.0 0.5 GO:0046785 microtubule polymerization(GO:0046785)
0.0 0.2 GO:0030007 cellular potassium ion homeostasis(GO:0030007) sodium ion export from cell(GO:0036376) sodium ion export(GO:0071436)
0.0 0.1 GO:0006729 tetrahydrobiopterin biosynthetic process(GO:0006729) tetrahydrobiopterin metabolic process(GO:0046146)
0.0 0.1 GO:0050819 negative regulation of coagulation(GO:0050819)
0.0 0.2 GO:0015936 coenzyme A metabolic process(GO:0015936)
0.0 0.0 GO:1990868 response to chemokine(GO:1990868) cellular response to chemokine(GO:1990869) negative regulation of lymphocyte migration(GO:2000402) negative regulation of T cell migration(GO:2000405)
0.0 0.2 GO:0032438 melanosome organization(GO:0032438)
0.0 0.1 GO:0010591 regulation of lamellipodium assembly(GO:0010591)
0.0 0.2 GO:0042542 response to hydrogen peroxide(GO:0042542)
0.0 0.2 GO:0033173 calcineurin-NFAT signaling cascade(GO:0033173)
0.0 0.7 GO:1902600 hydrogen ion transmembrane transport(GO:1902600)
0.0 0.3 GO:0051014 actin filament severing(GO:0051014)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.6 GO:0032584 growth cone membrane(GO:0032584)
0.1 0.4 GO:0070044 synaptobrevin 2-SNAP-25-syntaxin-1a complex(GO:0070044)
0.1 0.6 GO:0061617 MICOS complex(GO:0061617)
0.0 0.4 GO:0031931 TORC1 complex(GO:0031931)
0.0 0.7 GO:0033180 proton-transporting V-type ATPase, V1 domain(GO:0033180)
0.0 0.1 GO:0005947 mitochondrial alpha-ketoglutarate dehydrogenase complex(GO:0005947) mitochondrial tricarboxylic acid cycle enzyme complex(GO:0030062)
0.0 0.4 GO:0090533 sodium:potassium-exchanging ATPase complex(GO:0005890) cation-transporting ATPase complex(GO:0090533)
0.0 0.2 GO:0030314 junctional membrane complex(GO:0030314)
0.0 0.5 GO:0031209 SCAR complex(GO:0031209)
0.0 0.5 GO:0000164 protein phosphatase type 1 complex(GO:0000164)
0.0 0.1 GO:0018444 translation release factor complex(GO:0018444)
0.0 0.6 GO:0031430 M band(GO:0031430)
0.0 0.3 GO:0002102 podosome(GO:0002102)
0.0 0.9 GO:0031105 septin ring(GO:0005940) septin complex(GO:0031105) septin cytoskeleton(GO:0032156)
0.0 0.2 GO:0034045 pre-autophagosomal structure membrane(GO:0034045)
0.0 0.2 GO:0001401 mitochondrial sorting and assembly machinery complex(GO:0001401)
0.0 0.3 GO:0008540 proteasome regulatory particle, base subcomplex(GO:0008540)
0.0 0.1 GO:0097433 dense body(GO:0097433)
0.0 0.1 GO:0008290 F-actin capping protein complex(GO:0008290)
0.0 0.4 GO:0099569 cytoskeleton of presynaptic active zone(GO:0048788) presynaptic cytoskeleton(GO:0099569)
0.0 0.4 GO:0055038 recycling endosome membrane(GO:0055038)
0.0 1.4 GO:0044309 dendritic spine(GO:0043197) neuron spine(GO:0044309)
0.0 0.2 GO:0032154 cleavage furrow(GO:0032154) cell surface furrow(GO:0097610)
0.0 0.4 GO:0016514 SWI/SNF complex(GO:0016514)
0.0 0.1 GO:0030904 retromer complex(GO:0030904)
0.0 1.0 GO:0005871 kinesin complex(GO:0005871)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.5 GO:0008119 thiopurine S-methyltransferase activity(GO:0008119)
0.1 0.5 GO:0004365 glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity(GO:0004365) glyceraldehyde-3-phosphate dehydrogenase (NAD(P)+) (phosphorylating) activity(GO:0043891)
0.1 0.4 GO:0043183 vascular endothelial growth factor receptor 1 binding(GO:0043183)
0.1 0.3 GO:0097108 hedgehog family protein binding(GO:0097108)
0.1 0.2 GO:0000293 ferric-chelate reductase activity(GO:0000293)
0.1 0.4 GO:0005483 soluble NSF attachment protein activity(GO:0005483)
0.1 1.5 GO:0001540 beta-amyloid binding(GO:0001540)
0.1 0.2 GO:0047804 cysteine-S-conjugate beta-lyase activity(GO:0047804)
0.1 0.2 GO:0016215 stearoyl-CoA 9-desaturase activity(GO:0004768) acyl-CoA desaturase activity(GO:0016215) palmitoyl-CoA 9-desaturase activity(GO:0032896)
0.1 0.8 GO:0005504 fatty acid binding(GO:0005504)
0.1 0.5 GO:0071933 Arp2/3 complex binding(GO:0071933)
0.1 0.4 GO:0015189 L-lysine transmembrane transporter activity(GO:0015189)
0.1 0.4 GO:0016863 intramolecular oxidoreductase activity, transposing C=C bonds(GO:0016863)
0.1 0.2 GO:0008022 protein C-terminus binding(GO:0008022)
0.0 0.3 GO:0004128 cytochrome-b5 reductase activity, acting on NAD(P)H(GO:0004128)
0.0 0.2 GO:0004735 pyrroline-5-carboxylate reductase activity(GO:0004735)
0.0 0.3 GO:0036402 proteasome-activating ATPase activity(GO:0036402)
0.0 0.5 GO:0004859 phospholipase inhibitor activity(GO:0004859) lipase inhibitor activity(GO:0055102)
0.0 0.2 GO:0004694 eukaryotic translation initiation factor 2alpha kinase activity(GO:0004694)
0.0 0.2 GO:0004142 diacylglycerol cholinephosphotransferase activity(GO:0004142) ethanolaminephosphotransferase activity(GO:0004307)
0.0 0.2 GO:0070888 E-box binding(GO:0070888)
0.0 0.2 GO:0030060 L-malate dehydrogenase activity(GO:0030060)
0.0 0.1 GO:0030228 lipoprotein particle receptor activity(GO:0030228)
0.0 0.1 GO:0000035 acyl binding(GO:0000035)
0.0 0.3 GO:0016868 intramolecular transferase activity, phosphotransferases(GO:0016868)
0.0 0.2 GO:0033781 cholesterol 24-hydroxylase activity(GO:0033781)
0.0 0.4 GO:2001069 glycogen binding(GO:2001069)
0.0 0.1 GO:0008970 phosphatidylcholine 1-acylhydrolase activity(GO:0008970)
0.0 0.2 GO:0052650 NADP-retinol dehydrogenase activity(GO:0052650)
0.0 0.1 GO:0004938 alpha2-adrenergic receptor activity(GO:0004938)
0.0 0.2 GO:0036122 BMP binding(GO:0036122)
0.0 0.2 GO:0004630 phospholipase D activity(GO:0004630)
0.0 0.2 GO:0030160 GKAP/Homer scaffold activity(GO:0030160)
0.0 0.3 GO:0004687 myosin light chain kinase activity(GO:0004687)
0.0 0.3 GO:0031682 G-protein gamma-subunit binding(GO:0031682)
0.0 0.1 GO:0004692 cGMP-dependent protein kinase activity(GO:0004692)
0.0 0.3 GO:0046975 histone methyltransferase activity (H3-K36 specific)(GO:0046975)
0.0 0.4 GO:0001671 ATPase activator activity(GO:0001671)
0.0 0.2 GO:0004096 catalase activity(GO:0004096)
0.0 0.6 GO:0008574 ATP-dependent microtubule motor activity, plus-end-directed(GO:0008574)
0.0 0.1 GO:0098973 structural constituent of postsynaptic actin cytoskeleton(GO:0098973)
0.0 0.4 GO:0004550 nucleoside diphosphate kinase activity(GO:0004550)
0.0 0.2 GO:0051721 protein phosphatase 2A binding(GO:0051721)
0.0 0.1 GO:0003747 translation release factor activity(GO:0003747) translation termination factor activity(GO:0008079)
0.0 0.1 GO:0015288 porin activity(GO:0015288)
0.0 0.6 GO:0001786 phosphatidylserine binding(GO:0001786)
0.0 0.2 GO:0061578 Lys63-specific deubiquitinase activity(GO:0061578)
0.0 0.3 GO:0004697 protein kinase C activity(GO:0004697) calcium-dependent protein kinase C activity(GO:0004698)
0.0 0.2 GO:0019894 kinesin binding(GO:0019894)
0.0 0.1 GO:0019215 intermediate filament binding(GO:0019215)
0.0 0.4 GO:0004707 MAP kinase activity(GO:0004707)
0.0 0.1 GO:0016433 rRNA (adenine) methyltransferase activity(GO:0016433)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.2 ST TYPE I INTERFERON PATHWAY Type I Interferon (alpha/beta IFN) Pathway
0.0 0.1 SA FAS SIGNALING The TNF-type receptor Fas induces apoptosis on ligand binding.
0.0 0.4 SIG REGULATION OF THE ACTIN CYTOSKELETON BY RHO GTPASES Genes related to regulation of the actin cytoskeleton
0.0 0.2 PID REELIN PATHWAY Reelin signaling pathway
0.0 0.2 PID ERBB NETWORK PATHWAY ErbB receptor signaling network
0.0 0.6 PID NCADHERIN PATHWAY N-cadherin signaling events
0.0 0.2 PID HEDGEHOG 2PATHWAY Signaling events mediated by the Hedgehog family
0.0 0.3 PID SYNDECAN 4 PATHWAY Syndecan-4-mediated signaling events
0.0 0.2 PID TCR CALCIUM PATHWAY Calcium signaling in the CD4+ TCR pathway

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.5 REACTOME INSULIN RECEPTOR RECYCLING Genes involved in Insulin receptor recycling
0.0 0.4 REACTOME MTORC1 MEDIATED SIGNALLING Genes involved in mTORC1-mediated signalling
0.0 0.6 REACTOME INHIBITION OF INSULIN SECRETION BY ADRENALINE NORADRENALINE Genes involved in Inhibition of Insulin Secretion by Adrenaline/Noradrenaline
0.0 0.2 REACTOME PURINE CATABOLISM Genes involved in Purine catabolism
0.0 0.7 REACTOME GLUCONEOGENESIS Genes involved in Gluconeogenesis
0.0 0.3 REACTOME GLYCOGEN BREAKDOWN GLYCOGENOLYSIS Genes involved in Glycogen breakdown (glycogenolysis)
0.0 0.3 REACTOME PLATELET SENSITIZATION BY LDL Genes involved in Platelet sensitization by LDL
0.0 0.2 REACTOME ALPHA LINOLENIC ACID ALA METABOLISM Genes involved in alpha-linolenic acid (ALA) metabolism
0.0 0.2 REACTOME SYNTHESIS OF PE Genes involved in Synthesis of PE
0.0 0.3 REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS Genes involved in Cell-extracellular matrix interactions
0.0 0.6 REACTOME MYOGENESIS Genes involved in Myogenesis
0.0 0.2 REACTOME SHC1 EVENTS IN EGFR SIGNALING Genes involved in SHC1 events in EGFR signaling