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PRJNA195909:zebrafish embryo and larva development
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Results for jund_batf
Z-value: 1.04
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Transcription factors associated with jund_batf
Activity-expression correlation:
| Gene | Promoter | Pearson corr. coef. | P-value | Plot |
|---|---|---|---|---|
| batf | dr11_v1_chr20_+_46572550_46572550 | -0.82 | 6.9e-03 | Click! |
| jund | dr11_v1_chr2_-_56131312_56131312 | 0.14 | 7.2e-01 | Click! |
| Promoter | Log-likelihood | Transcript | Gene | Gene Info |
|---|---|---|---|---|
| chr22_-_26595027 Show fit | 1.96 |
ENSDART00000184162
|
|
|
| chr3_+_31621774 Show fit | 1.94 |
ENSDART00000076636
|
frizzled class receptor 2 |
|
| chr3_-_26017592 Show fit | 1.59 |
ENSDART00000030890
|
heme oxygenase 1a |
|
| chr22_+_16497670 Show fit | 1.58 |
ENSDART00000014330
|
immediate early response 5 |
|
| chr3_-_26017831 Show fit | 1.40 |
ENSDART00000179982
|
heme oxygenase 1a |
|
| chr3_+_24197934 Show fit | 1.39 |
ENSDART00000055609
|
activating transcription factor 4b |
|
| chr1_-_56176976 Show fit | 1.27 |
ENSDART00000052688
|
complement component c3a, duplicate 1 |
|
| chr20_+_572037 Show fit | 1.25 |
ENSDART00000028062
ENSDART00000152736 ENSDART00000031759 ENSDART00000162198 |
SET and MYND domain containing 2b |
|
| chr6_+_49095646 Show fit | 1.25 |
ENSDART00000103385
|
solute carrier family 25, member 55a |
|
| chr7_-_26436436 Show fit | 1.24 |
ENSDART00000019035
ENSDART00000123395 |
hairy-related 8a |
Network of associatons between targets according to the STRING database.
First level regulatory network of jund_batf
Gene Ontology Analysis
Gene overrepresentation in biological process category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 1.0 | 3.0 | GO:0043576 | respiratory gaseous exchange(GO:0007585) regulation of respiratory gaseous exchange(GO:0043576) |
| 0.6 | 1.9 | GO:0061341 | non-canonical Wnt signaling pathway involved in heart development(GO:0061341) |
| 0.0 | 1.5 | GO:0003333 | amino acid transmembrane transport(GO:0003333) |
| 0.2 | 1.3 | GO:0018026 | peptidyl-lysine monomethylation(GO:0018026) |
| 0.1 | 1.2 | GO:0043490 | acidic amino acid transport(GO:0015800) aspartate transport(GO:0015810) L-glutamate transport(GO:0015813) malate-aspartate shuttle(GO:0043490) |
| 0.1 | 1.2 | GO:0019471 | peptidyl-proline hydroxylation to 4-hydroxy-L-proline(GO:0018401) 4-hydroxyproline metabolic process(GO:0019471) |
| 0.0 | 1.2 | GO:0006956 | complement activation(GO:0006956) |
| 0.0 | 1.2 | GO:0050768 | negative regulation of neurogenesis(GO:0050768) |
| 0.3 | 1.1 | GO:0060547 | negative regulation of necroptotic process(GO:0060546) negative regulation of necrotic cell death(GO:0060547) |
| 0.1 | 1.0 | GO:0008343 | adult feeding behavior(GO:0008343) |
Gene overrepresentation in cellular component category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.1 | 1.8 | GO:1990589 | ATF4-CREB1 transcription factor complex(GO:1990589) |
| 0.0 | 1.4 | GO:0005788 | endoplasmic reticulum lumen(GO:0005788) |
| 0.0 | 0.9 | GO:0005885 | Arp2/3 protein complex(GO:0005885) |
| 0.0 | 0.9 | GO:0016342 | catenin complex(GO:0016342) |
| 0.0 | 0.8 | GO:0005666 | DNA-directed RNA polymerase III complex(GO:0005666) |
| 0.1 | 0.7 | GO:0042627 | chylomicron(GO:0042627) |
| 0.0 | 0.7 | GO:0005869 | dynactin complex(GO:0005869) |
| 0.0 | 0.7 | GO:0005834 | heterotrimeric G-protein complex(GO:0005834) |
| 0.1 | 0.5 | GO:0008290 | F-actin capping protein complex(GO:0008290) |
| 0.0 | 0.5 | GO:0046658 | anchored component of plasma membrane(GO:0046658) |
Gene overrepresentation in molecular function category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.5 | 3.0 | GO:0004392 | heme oxygenase (decyclizing) activity(GO:0004392) |
| 0.1 | 1.9 | GO:0042813 | Wnt-activated receptor activity(GO:0042813) |
| 0.0 | 1.6 | GO:0005184 | neuropeptide hormone activity(GO:0005184) |
| 0.1 | 1.3 | GO:0046975 | histone methyltransferase activity (H3-K36 specific)(GO:0046975) |
| 0.1 | 1.2 | GO:0015183 | L-aspartate transmembrane transporter activity(GO:0015183) |
| 0.1 | 1.2 | GO:0004656 | procollagen-proline 4-dioxygenase activity(GO:0004656) |
| 0.1 | 1.1 | GO:0043027 | cysteine-type endopeptidase inhibitor activity involved in apoptotic process(GO:0043027) cysteine-type endopeptidase regulator activity involved in apoptotic process(GO:0043028) |
| 0.1 | 1.0 | GO:0030274 | LIM domain binding(GO:0030274) |
| 0.2 | 0.9 | GO:0004657 | proline dehydrogenase activity(GO:0004657) |
| 0.0 | 0.9 | GO:0015175 | neutral amino acid transmembrane transporter activity(GO:0015175) |
Gene overrepresentation in curated gene sets: canonical pathways category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.1 | 1.9 | PID WNT SIGNALING PATHWAY | Wnt signaling network |
| 0.1 | 1.1 | SA CASPASE CASCADE | Apoptosis is mediated by caspases, cysteine proteases arranged in a proteolytic cascade. |
| 0.0 | 0.9 | PID RAC1 PATHWAY | RAC1 signaling pathway |
| 0.0 | 0.6 | PID INTEGRIN2 PATHWAY | Beta2 integrin cell surface interactions |
| 0.0 | 0.6 | PID HIF1 TFPATHWAY | HIF-1-alpha transcription factor network |
| 0.0 | 0.5 | PID BMP PATHWAY | BMP receptor signaling |
| 0.0 | 0.5 | ST ERK1 ERK2 MAPK PATHWAY | ERK1/ERK2 MAPK Pathway |
| 0.0 | 0.5 | PID PTP1B PATHWAY | Signaling events mediated by PTP1B |
| 0.0 | 0.3 | PID ALK1 PATHWAY | ALK1 signaling events |
| 0.0 | 0.2 | ST GRANULE CELL SURVIVAL PATHWAY | Granule Cell Survival Pathway is a specific case of more general PAC1 Receptor Pathway. |
Gene overrepresentation in curated gene sets: REACTOME pathways category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 2.4 | REACTOME CLASS B 2 SECRETIN FAMILY RECEPTORS | Genes involved in Class B/2 (Secretin family receptors) |
| 0.1 | 1.6 | REACTOME APOPTOTIC CLEAVAGE OF CELLULAR PROTEINS | Genes involved in Apoptotic cleavage of cellular proteins |
| 0.0 | 0.6 | REACTOME ACYL CHAIN REMODELLING OF PC | Genes involved in Acyl chain remodelling of PC |
| 0.1 | 0.5 | REACTOME GAMMA CARBOXYLATION TRANSPORT AND AMINO TERMINAL CLEAVAGE OF PROTEINS | Genes involved in Gamma-carboxylation, transport, and amino-terminal cleavage of proteins |
| 0.0 | 0.5 | REACTOME ERKS ARE INACTIVATED | Genes involved in ERKs are inactivated |
| 0.0 | 0.5 | REACTOME IRON UPTAKE AND TRANSPORT | Genes involved in Iron uptake and transport |
| 0.0 | 0.5 | REACTOME AMINO ACID TRANSPORT ACROSS THE PLASMA MEMBRANE | Genes involved in Amino acid transport across the plasma membrane |
| 0.0 | 0.5 | REACTOME NETRIN1 SIGNALING | Genes involved in Netrin-1 signaling |
| 0.1 | 0.3 | REACTOME SIGNALING BY ACTIVATED POINT MUTANTS OF FGFR1 | Genes involved in Signaling by activated point mutants of FGFR1 |
| 0.0 | 0.2 | REACTOME INTERACTIONS OF VPR WITH HOST CELLULAR PROTEINS | Genes involved in Interactions of Vpr with host cellular proteins |