Project

PRJNA195909:zebrafish embryo and larva development

Navigation
Downloads

Results for jun

Z-value: 0.84

Motif logo

Transcription factors associated with jun

Gene Symbol Gene ID Gene Info
ENSDARG00000043531 Jun proto-oncogene, AP-1 transcription factor subunit

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
jundr11_v1_chr20_+_15552657_155526570.551.2e-01Click!

Activity profile of jun motif

Sorted Z-values of jun motif

Promoter Log-likelihood Transcript Gene Gene Info
chr16_+_23403602 2.28 ENSDART00000159848
S100 calcium binding protein W
chr11_-_24681292 1.82 ENSDART00000089601
olfactomedin-like 3b
chr20_+_26880668 1.65 ENSDART00000077769
serpin peptidase inhibitor, clade B (ovalbumin), member 1
chr19_+_24488403 1.59 ENSDART00000052421
thioredoxin interacting protein a
chr22_-_26595027 1.21 ENSDART00000184162

chr23_-_21471022 1.18 ENSDART00000104206
hairy-related 4, tandem duplicate 2
chr1_-_59252973 1.13 ENSDART00000167061
si:ch1073-286c18.5
chr13_+_24280380 1.08 ENSDART00000184115
actin, alpha 1b, skeletal muscle
chr23_+_35714574 1.07 ENSDART00000164616
tubulin, alpha 1c
chr5_+_37087583 1.05 ENSDART00000049900
transgelin 2
chr5_-_30615901 1.05 ENSDART00000147769
si:ch211-117m20.5
chr2_+_48288461 1.03 ENSDART00000141495
hes family bHLH transcription factor 6
chr10_+_38610741 1.01 ENSDART00000126444
matrix metallopeptidase 13a
chr16_+_23398369 0.99 ENSDART00000037694
S100 calcium binding protein A10b
chr7_-_35432901 0.97 ENSDART00000026712
matrix metallopeptidase 2
chr21_+_25765734 0.96 ENSDART00000021664
claudin b
chr1_-_25679339 0.95 ENSDART00000161703
ENSDART00000054230
fibrinogen gamma chain
chr23_+_36130883 0.95 ENSDART00000103132
homeobox C4a
chr5_-_25582721 0.95 ENSDART00000123986
annexin A1a
chr20_-_26531850 0.95 ENSDART00000183317
ENSDART00000131994
methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1 like
chr16_-_21785261 0.91 ENSDART00000078858
si:ch73-86n18.1
chr8_+_7359294 0.90 ENSDART00000121708
proprotein convertase subtilisin/kexin type 1 inhibitor, like
chr21_+_22845317 0.88 ENSDART00000065555
baculoviral IAP repeat containing 2
chr20_-_26532167 0.87 ENSDART00000061914
methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1 like
chr11_+_13630107 0.86 ENSDART00000172220
si:ch211-1a19.3
chr5_-_20195350 0.86 ENSDART00000139675
D-amino-acid oxidase, tandem duplicate 1
chr19_-_7420867 0.84 ENSDART00000081741
RAB25, member RAS oncogene family a
chr19_+_7567763 0.81 ENSDART00000140411
S100 calcium binding protein A11
chr4_-_16412084 0.79 ENSDART00000188460
decorin
chr2_+_47581997 0.79 ENSDART00000112579
secretogranin II (chromogranin C), b
chr3_+_27027781 0.78 ENSDART00000065495
epithelial membrane protein 2
chr16_+_42829735 0.77 ENSDART00000014956
polymerase (RNA) III (DNA directed) polypeptide G like b
chr16_-_45225520 0.77 ENSDART00000158855
FXYD domain containing ion transport regulator 1 (phospholemman)
chr6_-_49063085 0.76 ENSDART00000156124
si:ch211-105j21.9
chr19_-_5332784 0.74 ENSDART00000010373
keratin, type 1, gene 19d
chr2_-_2020044 0.74 ENSDART00000024135
tubulin, beta 2A class IIa
chr1_-_25177086 0.73 ENSDART00000144711
ENSDART00000177225
transmembrane protein 154
chr7_-_28696556 0.73 ENSDART00000148822
adhesion G protein-coupled receptor G1
chr2_+_47582681 0.73 ENSDART00000187579
secretogranin II (chromogranin C), b
chr9_-_48370645 0.73 ENSDART00000140185
collagen, type XXVIII, alpha 2a
chr4_-_6809323 0.73 ENSDART00000099467
interferon-related developmental regulator 1
chr1_+_12766351 0.72 ENSDART00000165785
protocadherin 10a
chr11_+_6116503 0.70 ENSDART00000176170
nuclear receptor subfamily 2, group F, member 6b
chr13_-_16222388 0.65 ENSDART00000182861
zgc:110045
chr2_+_30379650 0.64 ENSDART00000129542
cysteine-rich secretory protein LCCL domain containing 1b
chr1_-_5746030 0.64 ENSDART00000150863
neuropilin 2a
chr20_-_43771871 0.63 ENSDART00000153304
matrilin 3a
chr2_+_35612621 0.63 ENSDART00000143082
si:dkey-4i23.5
chr7_+_25033924 0.62 ENSDART00000170873
sb:cb1058
chr8_+_39511932 0.62 ENSDART00000113511
leucine zipper, putative tumor suppressor 1
chr6_-_18976168 0.62 ENSDART00000170039
septin 9b
chr10_+_37145007 0.62 ENSDART00000131777
CUE domain containing 1a
chr11_-_18253111 0.61 ENSDART00000125984
musculoskeletal, embryonic nuclear protein 1b
chr8_+_41647539 0.61 ENSDART00000136492
ENSDART00000138799
ENSDART00000134404
si:ch211-158d24.4
chr5_-_55623443 0.61 ENSDART00000005671
ENSDART00000176341
heterogeneous nuclear ribonucleoprotein K, like
chr20_+_34915945 0.60 ENSDART00000153064
synaptosomal-associated protein, 25a
chr13_+_829585 0.59 ENSDART00000029051
glutathione S-transferase, alpha tandem duplicate 2
chr3_-_26017592 0.59 ENSDART00000030890
heme oxygenase 1a
chr11_+_13629528 0.59 ENSDART00000186509
si:ch211-1a19.3
chr8_+_39634114 0.59 ENSDART00000144293
musashi RNA-binding protein 1
chr21_-_30545121 0.59 ENSDART00000019199
RAB39B, member RAS oncogene family a
chr10_+_22771176 0.59 ENSDART00000192046
transmembrane protein 88 a
chr3_-_26017831 0.58 ENSDART00000179982
heme oxygenase 1a
chr12_+_25945560 0.58 ENSDART00000109799
multimerin 2b
chr23_+_9067131 0.56 ENSDART00000144533
cerebral cavernous malformation 2-like
chr13_+_50368668 0.56 ENSDART00000127610
DnaJ (Hsp40) homolog, subfamily C, member 12
chr6_+_56141852 0.56 ENSDART00000149665
transcription factor AP-2 gamma (activating enhancer binding protein 2 gamma)
chr11_+_6116096 0.54 ENSDART00000159680
nuclear receptor subfamily 2, group F, member 6b
chr13_+_23988442 0.54 ENSDART00000010918
angiotensinogen
chr16_+_42830152 0.54 ENSDART00000159730
polymerase (RNA) III (DNA directed) polypeptide G like b
chr4_+_16715267 0.52 ENSDART00000143849
plakophilin 2
chr9_-_710896 0.52 ENSDART00000180478
NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 3
chr5_+_15819651 0.51 ENSDART00000081230
ENSDART00000186969
ENSDART00000134206
heat shock protein b8
chr19_-_103289 0.51 ENSDART00000143118
adhesion G protein-coupled receptor B1b
chr14_+_33882973 0.51 ENSDART00000019396
chloride intracellular channel 2
chr7_-_8470860 0.48 ENSDART00000172793
hypothetical protein LOC564481
chr7_-_52963493 0.48 ENSDART00000052029
cocaine- and amphetamine-regulated transcript 3
chr13_+_35339182 0.48 ENSDART00000019323
jagged 1b
chr2_+_47582488 0.48 ENSDART00000149967
secretogranin II (chromogranin C), b
chr5_+_37785152 0.48 ENSDART00000053511
ENSDART00000189812
myosin Ic, paralog a
chr3_+_20156956 0.48 ENSDART00000125281
nerve growth factor receptor a (TNFR superfamily, member 16)
chr9_-_2594410 0.48 ENSDART00000188306
ENSDART00000164276
sp9 transcription factor
chr10_+_38593645 0.48 ENSDART00000011573
matrix metallopeptidase 13a
chr8_+_32406885 0.47 ENSDART00000167600
epithelial mitogen homolog (mouse)
chr20_-_42972599 0.47 ENSDART00000100751
proopiomelanocortin b
chr3_-_39648021 0.47 ENSDART00000055171
GRB2-related adaptor protein a
chr5_-_26879302 0.46 ENSDART00000098571
ENSDART00000139086
zgc:64051
chr14_+_33722950 0.46 ENSDART00000075312
apelin
chr14_-_17588345 0.46 ENSDART00000143486
selenoprotein T, 2
chr24_+_20575259 0.46 ENSDART00000010488
kelch-like family member 40b
chr3_+_21189766 0.44 ENSDART00000078807
zgc:123295
chr19_-_41404870 0.44 ENSDART00000167772
SEM1, 26S proteasome complex subunit
chr16_-_48673938 0.44 ENSDART00000156969
notch homolog, like
chr17_-_7861219 0.43 ENSDART00000148604
spectrin repeat containing, nuclear envelope 1b
chr16_+_50006872 0.43 ENSDART00000157100
ubiquitin-conjugating enzyme E2E 2
chr5_-_34616599 0.43 ENSDART00000050271
ENSDART00000097975
hexosaminidase B (beta polypeptide)
chr7_+_69019851 0.42 ENSDART00000162891

chr1_-_22861348 0.42 ENSDART00000139412
si:dkey-92j12.6
chr1_+_59090743 0.42 ENSDART00000100199
microfibril associated protein 4
chr1_+_41849152 0.41 ENSDART00000053685
spermine oxidase
chr9_-_6372535 0.41 ENSDART00000149189
esophageal cancer related gene 4a
chr19_-_38539670 0.41 ENSDART00000136775
collagen, type XVI, alpha 1
chr19_+_22216778 0.40 ENSDART00000052521
nuclear factor of activated T cells 1
chr23_-_1017605 0.40 ENSDART00000138290
cadherin 26, tandem duplicate 1
chr19_-_42573219 0.40 ENSDART00000126021
ENSDART00000133695
ENSDART00000131558
zgc:103438
chr8_-_25338709 0.40 ENSDART00000131616
ATP synthase peripheral stalk-membrane subunit b
chr1_+_59090972 0.39 ENSDART00000171497
microfibril associated protein 4
chr4_-_73787702 0.39 ENSDART00000136328
ENSDART00000150546
si:dkey-262g12.3
chr25_-_22191733 0.39 ENSDART00000067478
plakophilin 3a
chr25_-_37331513 0.39 ENSDART00000111862
low density lipoprotein receptor class A domain containing 3
chr20_-_40319890 0.39 ENSDART00000075112
clavesin 2
chr17_-_52091999 0.38 ENSDART00000019766
transforming growth factor, beta 3
chr15_-_46779934 0.38 ENSDART00000085136
chloride channel 2c
chr7_+_23875269 0.38 ENSDART00000101406
RAB39B, member RAS oncogene family b
chr20_-_25626198 0.37 ENSDART00000126716
phosphoribosylaminoimidazole carboxylase, phosphoribosylaminoimidazole succinocarboxamide synthetase
chr10_+_4499943 0.37 ENSDART00000125299
polo-like kinase 2a (Drosophila)
chr25_+_21324588 0.37 ENSDART00000151842
leucine rich repeat neuronal 3a
chr7_+_48460239 0.37 ENSDART00000052113
leucine rich repeat and Ig domain containing 1b
chr23_+_42336084 0.37 ENSDART00000158959
ENSDART00000161812
cytochrome P450, family 2, subfamily AA, polypeptide 7
cytochrome P450, family 2, subfamily AA, polypeptide 8
chr10_-_3295197 0.37 ENSDART00000109131
slc25a1 solute carrier family 25 (mitochondrial carrier; citrate transporter), member 1b
chr3_+_37574885 0.36 ENSDART00000055225
wingless-type MMTV integration site family, member 9B
chr7_-_17690983 0.36 ENSDART00000009367
mitogen-activated protein kinase kinase kinase kinase 2
chr16_-_36834505 0.36 ENSDART00000141275
ENSDART00000139588
ENSDART00000041993
purine nucleoside phosphorylase 4b
chr3_-_48259289 0.36 ENSDART00000160717
zinc finger protein 750
chr7_+_20298333 0.35 ENSDART00000023089
ENSDART00000131019
acyl-CoA dehydrogenase very long chain
chr23_-_7797207 0.35 ENSDART00000181611
myelin transcription factor 1b
chr7_+_34492744 0.35 ENSDART00000109635
ENSDART00000173844
calmodulin-like 4a
chr7_-_22941472 0.35 ENSDART00000190334
TNF superfamily member 10, like
chr14_+_49382180 0.34 ENSDART00000158329
TNFAIP3 interacting protein 1
chr22_+_16497670 0.34 ENSDART00000014330
immediate early response 5
chr14_+_30279391 0.34 ENSDART00000172794
fibrinogen-like 1
chr23_-_4915118 0.34 ENSDART00000060714
ATPase H+ transporting accessory protein 1a
chr10_-_27566481 0.34 ENSDART00000078920
autism susceptibility candidate 2a
chr23_+_24124684 0.34 ENSDART00000144478
si:dkey-21o19.2
chr9_+_41024973 0.34 ENSDART00000014660
ENSDART00000144467
ORMDL sphingolipid biosynthesis regulator 1
chr18_+_16125852 0.34 ENSDART00000061106
basic helix-loop-helix family, member e41
chr22_-_11724563 0.33 ENSDART00000190796
ENSDART00000184744
keratin 222
chr11_-_10770053 0.33 ENSDART00000179213
solute carrier family 4, sodium bicarbonate transporter, member 10a
chr15_+_9327252 0.33 ENSDART00000144381
sarcoglycan, gamma
chr6_-_31224563 0.32 ENSDART00000104616
leptin receptor
chr19_+_37120491 0.32 ENSDART00000032341
penta-EF-hand domain containing 1
chr7_+_69470442 0.32 ENSDART00000189593
GABA(A) receptor-associated protein b
chr16_-_27628994 0.32 ENSDART00000157407
NAC alpha domain containing
chr21_-_42100471 0.32 ENSDART00000166148
gamma-aminobutyric acid (GABA) A receptor, alpha 1
chr10_-_43928937 0.32 ENSDART00000168014
ENSDART00000086220
multiple C2 domains, transmembrane 1b
chr13_-_21701323 0.32 ENSDART00000164112
si:dkey-191g9.7
chr7_+_20587506 0.31 ENSDART00000172416
ENSDART00000170633
si:dkey-19b23.7
chr5_+_42280372 0.31 ENSDART00000142855
T-box 6, like
chr13_-_17729474 0.31 ENSDART00000013011
voltage-dependent anion channel 2
chr1_+_59073436 0.31 ENSDART00000161642
si:zfos-2330d3.3
chr17_+_45413324 0.30 ENSDART00000124911
ezrin a
chr4_+_1600034 0.30 ENSDART00000146779
solute carrier family 38, member 2
chr15_-_42736433 0.30 ENSDART00000154379
si:ch211-181d7.1
chr3_+_22375596 0.30 ENSDART00000188243
ENSDART00000181506
Rho GTPase activating protein 27, like
chr12_+_20587179 0.29 ENSDART00000170127
arylsulfatase G
chr13_-_37122217 0.29 ENSDART00000133242
spectrin repeat containing, nuclear envelope 2b
chr1_+_7988052 0.29 ENSDART00000167552

chr18_-_26785861 0.29 ENSDART00000098361
neuromedin Ba
chr16_+_10972733 0.29 ENSDART00000049323
POU class 2 homeobox 2a
chr22_-_32392252 0.28 ENSDART00000148681
ENSDART00000137945
poly(rC) binding protein 4
chr13_-_15982707 0.28 ENSDART00000186911
ENSDART00000181072
IKAROS family zinc finger 1 (Ikaros)
chr23_-_28239750 0.28 ENSDART00000003548
zinc finger protein 385A
chr1_-_35694978 0.28 ENSDART00000136157
si:dkey-27h10.2
chr11_+_36158134 0.28 ENSDART00000189827
ENSDART00000163330
glutamate receptor, metabotropic 2b
chr2_-_985417 0.27 ENSDART00000140540
si:ch211-241e1.3
chr23_-_1017428 0.27 ENSDART00000110588
ENSDART00000183158
cadherin 26, tandem duplicate 1
chr1_-_55116453 0.27 ENSDART00000142348
SERTA domain containing 2a
chr6_-_24143923 0.27 ENSDART00000157948
si:ch73-389b16.1
chr4_-_13902188 0.27 ENSDART00000032805
glucoside xylosyltransferase 1b
chr22_-_10110959 0.27 ENSDART00000031005
ENSDART00000147580
glutaminase 2b (liver, mitochondrial)
chr10_+_31222433 0.26 ENSDART00000185080
transmembrane protein 218
chr1_+_14253118 0.26 ENSDART00000161996
chemokine (C-X-C motif) ligand 8a
chr10_+_39263827 0.26 ENSDART00000172509
FAD-dependent oxidoreductase domain containing 1
chr5_-_46896541 0.26 ENSDART00000133240
EGF-like repeats and discoidin I-like domains 3a
chr23_-_29376859 0.26 ENSDART00000146411
somatostatin 6
chr6_-_43449013 0.25 ENSDART00000122423
2-epi-5-epi-valiolone synthase
chr25_-_8030425 0.25 ENSDART00000014964
calcium/calmodulin-dependent protein kinase 1Db
chr3_+_7617353 0.25 ENSDART00000165551
zgc:109949
chr18_+_3052408 0.25 ENSDART00000181563
potassium channel tetramerization domain containing 14
chr5_-_48260145 0.25 ENSDART00000044083
ENSDART00000163250
ENSDART00000135911
myocyte enhancer factor 2cb
chr7_+_50395856 0.25 ENSDART00000032324
HD domain containing 3
chr2_-_32558795 0.25 ENSDART00000140026
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 3a
chr10_+_31222656 0.24 ENSDART00000140988
ENSDART00000143387
transmembrane protein 218
chr8_-_23573084 0.24 ENSDART00000139084
Wiskott-Aldrich syndrome (eczema-thrombocytopenia) b
chr9_-_42418470 0.24 ENSDART00000144353
calcitonin receptor-like a
chr6_+_52350443 0.23 ENSDART00000151612
ENSDART00000151349
si:ch211-239j9.1
chr20_+_26095530 0.23 ENSDART00000139350
spectrin repeat containing, nuclear envelope 1a
chr3_-_58189429 0.23 ENSDART00000156092
si:ch211-256e16.11
chr3_-_32320537 0.23 ENSDART00000113550
ENSDART00000168483
si:dkey-16p21.7
chr1_+_56447107 0.23 ENSDART00000091924

chr5_+_9037650 0.23 ENSDART00000158226
si:ch211-155m12.1
chr15_-_31177324 0.23 ENSDART00000008854
WD repeat and SOCS box containing 1
chr23_+_16814968 0.23 ENSDART00000161299
zgc:100832
chr1_+_45323142 0.23 ENSDART00000132210
epithelial membrane protein 1
chr20_-_35578435 0.23 ENSDART00000142444
adhesion G protein-coupled receptor F6
chr15_+_29123031 0.23 ENSDART00000133988
ENSDART00000060030
zgc:101731
chr8_-_38105053 0.22 ENSDART00000131546
adhesion G protein-coupled receptor A2
chr19_+_48018464 0.22 ENSDART00000172307
ENSDART00000163848
si:ch1073-205c8.3
chr23_-_437467 0.22 ENSDART00000192106
tetraspanin 2b
chr1_-_58913813 0.22 ENSDART00000056494
zgc:171687

Network of associatons between targets according to the STRING database.

First level regulatory network of jun

PNG image of the network

In order to view interactive SVG image please either update your browser to latest version or install SVG plugin.


View svg image
View png image

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 1.2 GO:0043576 respiratory gaseous exchange(GO:0007585) regulation of respiratory gaseous exchange(GO:0043576)
0.3 0.8 GO:0001977 renal system process involved in regulation of blood volume(GO:0001977) renal system process involved in regulation of systemic arterial blood pressure(GO:0003071) regulation of glomerular filtration(GO:0003093)
0.2 0.9 GO:0060547 negative regulation of necroptotic process(GO:0060546) negative regulation of necrotic cell death(GO:0060547)
0.2 0.9 GO:0009080 alanine metabolic process(GO:0006522) alanine catabolic process(GO:0006524) pyruvate family amino acid metabolic process(GO:0009078) pyruvate family amino acid catabolic process(GO:0009080) D-alanine family amino acid metabolic process(GO:0046144) D-alanine metabolic process(GO:0046436) D-alanine catabolic process(GO:0055130)
0.2 0.6 GO:1905208 negative regulation of striated muscle cell differentiation(GO:0051154) negative regulation of cardiac muscle tissue development(GO:0055026) cardiac muscle cell fate commitment(GO:0060923) canonical Wnt signaling pathway involved in cardiac muscle cell fate commitment(GO:0061317) regulation of canonical Wnt signaling pathway involved in cardiac muscle cell fate commitment(GO:1901295) negative regulation of canonical Wnt signaling pathway involved in cardiac muscle cell fate commitment(GO:1901296) negative regulation of cardiocyte differentiation(GO:1905208) negative regulation of cardiac muscle cell differentiation(GO:2000726)
0.2 0.9 GO:0032663 neutrophil apoptotic process(GO:0001781) regulation of T-helper 1 type immune response(GO:0002825) positive regulation of T-helper 1 type immune response(GO:0002827) negative regulation of type 2 immune response(GO:0002829) inflammatory cell apoptotic process(GO:0006925) regulation of prostaglandin biosynthetic process(GO:0031392) positive regulation of prostaglandin biosynthetic process(GO:0031394) regulation of phospholipase A2 activity(GO:0032429) interleukin-2 production(GO:0032623) regulation of interleukin-2 production(GO:0032663) positive regulation of interleukin-2 production(GO:0032743) myeloid cell apoptotic process(GO:0033028) regulation of neutrophil apoptotic process(GO:0033029) positive regulation of neutrophil apoptotic process(GO:0033031) regulation of myeloid cell apoptotic process(GO:0033032) positive regulation of myeloid cell apoptotic process(GO:0033034) T-helper 1 type immune response(GO:0042088) positive regulation of CD4-positive, alpha-beta T cell differentiation(GO:0043372) T-helper 1 cell differentiation(GO:0045063) positive regulation of T-helper cell differentiation(GO:0045624) regulation of T-helper 1 cell differentiation(GO:0045625) positive regulation of T-helper 1 cell differentiation(GO:0045627) regulation of T-helper 2 cell differentiation(GO:0045628) negative regulation of T-helper 2 cell differentiation(GO:0045629) positive regulation of fatty acid biosynthetic process(GO:0045723) positive regulation of alpha-beta T cell differentiation(GO:0046638) neutrophil clearance(GO:0097350) negative regulation of phospholipase A2 activity(GO:1900138) positive regulation of CD4-positive, alpha-beta T cell activation(GO:2000516) regulation of unsaturated fatty acid biosynthetic process(GO:2001279) positive regulation of unsaturated fatty acid biosynthetic process(GO:2001280)
0.2 0.5 GO:0098528 skeletal muscle fiber differentiation(GO:0098528)
0.1 0.7 GO:0035988 chondrocyte proliferation(GO:0035988)
0.1 0.4 GO:0070314 G1 to G0 transition(GO:0070314)
0.1 0.5 GO:0090387 phagosome maturation involved in apoptotic cell clearance(GO:0090386) phagolysosome assembly involved in apoptotic cell clearance(GO:0090387)
0.1 0.7 GO:0070445 regulation of oligodendrocyte progenitor proliferation(GO:0070445)
0.1 1.8 GO:0035999 tetrahydrofolate interconversion(GO:0035999)
0.1 0.4 GO:1990791 dorsal root ganglion development(GO:1990791)
0.1 0.5 GO:0030326 embryonic limb morphogenesis(GO:0030326)
0.1 0.4 GO:0006843 mitochondrial citrate transport(GO:0006843)
0.1 0.3 GO:0002432 granuloma formation(GO:0002432) chronic inflammatory response(GO:0002544) regulation of granuloma formation(GO:0002631) regulation of chronic inflammatory response(GO:0002676)
0.1 0.3 GO:0003322 pancreatic A cell development(GO:0003322)
0.1 0.3 GO:2000303 regulation of sphingolipid biosynthetic process(GO:0090153) negative regulation of sphingolipid biosynthetic process(GO:0090155) negative regulation of ceramide biosynthetic process(GO:1900060) regulation of membrane lipid metabolic process(GO:1905038) regulation of ceramide biosynthetic process(GO:2000303)
0.1 2.5 GO:0044243 collagen catabolic process(GO:0030574) multicellular organism catabolic process(GO:0044243)
0.1 0.5 GO:0090133 mesendoderm migration(GO:0090133) cell migration involved in mesendoderm migration(GO:0090134)
0.1 1.2 GO:0001867 complement activation, lectin pathway(GO:0001867)
0.1 0.5 GO:0045110 intermediate filament bundle assembly(GO:0045110)
0.1 1.0 GO:0072378 blood coagulation, fibrin clot formation(GO:0072378)
0.1 0.3 GO:0048939 anterior lateral line nerve glial cell differentiation(GO:0048913) myelination of anterior lateral line nerve axons(GO:0048914) anterior lateral line nerve glial cell development(GO:0048939) anterior lateral line nerve glial cell morphogenesis involved in differentiation(GO:0048940)
0.1 0.2 GO:1990416 synaptic signaling via neuropeptide(GO:0099538) trans-synaptic signaling by neuropeptide(GO:0099540) trans-synaptic signaling by neuropeptide, modulating synaptic transmission(GO:0099551) cellular response to brain-derived neurotrophic factor stimulus(GO:1990416)
0.1 0.3 GO:0070208 protein heterotrimerization(GO:0070208)
0.1 2.0 GO:1903670 regulation of sprouting angiogenesis(GO:1903670)
0.1 0.5 GO:0008343 adult feeding behavior(GO:0008343)
0.1 0.2 GO:1904088 regulation of convergent extension involved in axis elongation(GO:1901232) positive regulation of epiboly involved in gastrulation with mouth forming second(GO:1904088)
0.1 0.3 GO:0033119 negative regulation of RNA splicing(GO:0033119) negative regulation of mRNA splicing, via spliceosome(GO:0048025)
0.1 0.5 GO:0045741 positive regulation of epidermal growth factor-activated receptor activity(GO:0045741) positive regulation of receptor activity(GO:2000273)
0.1 1.2 GO:0048936 peripheral nervous system neuron axonogenesis(GO:0048936)
0.0 0.6 GO:0014036 neural crest cell fate commitment(GO:0014034) neural crest cell fate specification(GO:0014036)
0.0 1.3 GO:0006383 transcription from RNA polymerase III promoter(GO:0006383)
0.0 0.6 GO:0043248 proteasome assembly(GO:0043248)
0.0 0.2 GO:0030299 intestinal cholesterol absorption(GO:0030299)
0.0 0.3 GO:0048207 vesicle targeting, rough ER to cis-Golgi(GO:0048207) COPII vesicle coating(GO:0048208)
0.0 0.7 GO:0097324 melanocyte migration(GO:0097324)
0.0 0.2 GO:0034146 toll-like receptor 5 signaling pathway(GO:0034146)
0.0 0.2 GO:0071380 response to prostaglandin E(GO:0034695) cellular response to prostaglandin E stimulus(GO:0071380)
0.0 0.1 GO:0019418 sulfide oxidation(GO:0019418) sulfide oxidation, using sulfide:quinone oxidoreductase(GO:0070221)
0.0 0.8 GO:0010257 NADH dehydrogenase complex assembly(GO:0010257) mitochondrial respiratory chain complex I assembly(GO:0032981) mitochondrial respiratory chain complex I biogenesis(GO:0097031)
0.0 0.3 GO:2001238 positive regulation of extrinsic apoptotic signaling pathway(GO:2001238)
0.0 0.6 GO:0030947 regulation of vascular endothelial growth factor receptor signaling pathway(GO:0030947)
0.0 0.3 GO:0006537 glutamate biosynthetic process(GO:0006537) glutamine catabolic process(GO:0006543)
0.0 2.7 GO:0010951 negative regulation of endopeptidase activity(GO:0010951)
0.0 0.2 GO:1902093 positive regulation of sperm motility(GO:1902093)
0.0 0.2 GO:0035889 otolith tethering(GO:0035889)
0.0 0.3 GO:0006868 glutamine transport(GO:0006868)
0.0 0.2 GO:0003321 positive regulation of heart rate by epinephrine-norepinephrine(GO:0001996) positive regulation of blood pressure by epinephrine-norepinephrine(GO:0003321) positive regulation of heart rate(GO:0010460)
0.0 0.8 GO:0010508 positive regulation of autophagy(GO:0010508)
0.0 0.4 GO:0060325 face morphogenesis(GO:0060325)
0.0 0.3 GO:0030431 sleep(GO:0030431)
0.0 0.8 GO:0016082 synaptic vesicle priming(GO:0016082)
0.0 0.2 GO:0006337 nucleosome disassembly(GO:0006337) chromatin disassembly(GO:0031498) protein-DNA complex disassembly(GO:0032986)
0.0 0.5 GO:0036444 calcium ion transmembrane import into mitochondrion(GO:0036444)
0.0 0.4 GO:0033173 calcineurin-NFAT signaling cascade(GO:0033173)
0.0 0.8 GO:0032482 Rab protein signal transduction(GO:0032482)
0.0 0.2 GO:0045050 protein insertion into ER membrane by stop-transfer membrane-anchor sequence(GO:0045050)
0.0 0.4 GO:0048096 chromatin-mediated maintenance of transcription(GO:0048096)
0.0 0.7 GO:0048814 regulation of dendrite morphogenesis(GO:0048814)
0.0 0.2 GO:0006189 'de novo' IMP biosynthetic process(GO:0006189)
0.0 0.2 GO:0045901 positive regulation of translational elongation(GO:0045901) positive regulation of translational termination(GO:0045905)
0.0 1.0 GO:0002028 regulation of sodium ion transport(GO:0002028)
0.0 0.2 GO:0031269 pseudopodium organization(GO:0031268) pseudopodium assembly(GO:0031269) regulation of pseudopodium assembly(GO:0031272) positive regulation of pseudopodium assembly(GO:0031274)
0.0 0.1 GO:0034058 endosomal vesicle fusion(GO:0034058)
0.0 0.3 GO:0006995 cellular response to nitrogen starvation(GO:0006995) cellular response to nitrogen levels(GO:0043562)
0.0 0.4 GO:0040023 nuclear migration(GO:0007097) establishment of nucleus localization(GO:0040023)
0.0 0.4 GO:0015985 energy coupled proton transport, down electrochemical gradient(GO:0015985) ATP synthesis coupled proton transport(GO:0015986)
0.0 0.3 GO:0033077 T cell differentiation in thymus(GO:0033077) thymocyte aggregation(GO:0071594)
0.0 0.5 GO:0003323 glandular epithelial cell development(GO:0002068) type B pancreatic cell development(GO:0003323)
0.0 0.4 GO:0070936 protein K48-linked ubiquitination(GO:0070936)
0.0 0.2 GO:2000601 positive regulation of actin nucleation(GO:0051127) positive regulation of Arp2/3 complex-mediated actin nucleation(GO:2000601)
0.0 0.3 GO:0006516 glycoprotein catabolic process(GO:0006516)
0.0 0.3 GO:0021884 forebrain neuron development(GO:0021884)
0.0 0.1 GO:0045898 regulation of RNA polymerase II transcriptional preinitiation complex assembly(GO:0045898) positive regulation of RNA polymerase II transcriptional preinitiation complex assembly(GO:0045899)
0.0 1.1 GO:0014904 myotube cell development(GO:0014904) skeletal muscle fiber development(GO:0048741)
0.0 0.2 GO:0046887 positive regulation of hormone secretion(GO:0046887)
0.0 0.1 GO:1990118 sodium ion import(GO:0097369) sodium ion import across plasma membrane(GO:0098719) sodium ion import into cell(GO:1990118)
0.0 0.0 GO:0002828 regulation of type 2 immune response(GO:0002828)
0.0 0.4 GO:0080171 lysosome organization(GO:0007040) lytic vacuole organization(GO:0080171)
0.0 0.2 GO:0060396 growth hormone receptor signaling pathway(GO:0060396) response to growth hormone(GO:0060416) cellular response to growth hormone stimulus(GO:0071378)
0.0 0.4 GO:0055064 chloride ion homeostasis(GO:0055064)
0.0 0.1 GO:1904030 negative regulation of cyclin-dependent protein serine/threonine kinase activity(GO:0045736) negative regulation of cyclin-dependent protein kinase activity(GO:1904030)
0.0 0.1 GO:0061588 calcium activated phospholipid scrambling(GO:0061588)
0.0 0.5 GO:1902036 regulation of hematopoietic stem cell differentiation(GO:1902036)
0.0 0.2 GO:0043124 negative regulation of I-kappaB kinase/NF-kappaB signaling(GO:0043124)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.0 GO:0005577 fibrinogen complex(GO:0005577)
0.1 0.5 GO:0060171 stereocilium membrane(GO:0060171)
0.1 0.4 GO:1990909 Wnt signalosome(GO:1990909)
0.1 0.6 GO:0070032 synaptobrevin 2-SNAP-25-syntaxin-1a-complexin I complex(GO:0070032)
0.1 0.3 GO:0035339 SPOTS complex(GO:0035339)
0.1 1.1 GO:0005869 dynactin complex(GO:0005869)
0.1 0.7 GO:0008541 proteasome regulatory particle, lid subcomplex(GO:0008541)
0.1 0.9 GO:0016328 lateral plasma membrane(GO:0016328)
0.1 1.3 GO:0005666 DNA-directed RNA polymerase III complex(GO:0005666)
0.1 0.3 GO:0033181 plasma membrane proton-transporting V-type ATPase complex(GO:0033181)
0.1 0.3 GO:0005854 nascent polypeptide-associated complex(GO:0005854)
0.0 0.3 GO:0016012 sarcoglycan complex(GO:0016012)
0.0 0.5 GO:0014704 intercalated disc(GO:0014704)
0.0 0.2 GO:0070195 growth hormone receptor complex(GO:0070195)
0.0 0.7 GO:0005640 nuclear outer membrane(GO:0005640)
0.0 0.2 GO:0097225 sperm midpiece(GO:0097225)
0.0 1.0 GO:0017053 transcriptional repressor complex(GO:0017053)
0.0 0.4 GO:0000276 mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)(GO:0000276)
0.0 2.0 GO:0030141 secretory granule(GO:0030141)
0.0 0.2 GO:0031371 ubiquitin conjugating enzyme complex(GO:0031371)
0.0 0.1 GO:0008290 F-actin capping protein complex(GO:0008290)
0.0 0.3 GO:0030057 desmosome(GO:0030057)
0.0 0.1 GO:0030428 cell septum(GO:0030428)
0.0 0.5 GO:0031463 Cul3-RING ubiquitin ligase complex(GO:0031463)
0.0 0.1 GO:0071914 prominosome(GO:0071914)
0.0 0.2 GO:0071564 npBAF complex(GO:0071564)
0.0 0.2 GO:0072546 ER membrane protein complex(GO:0072546)
0.0 0.2 GO:1990589 ATF4-CREB1 transcription factor complex(GO:1990589)
0.0 0.6 GO:0016342 catenin complex(GO:0016342)
0.0 2.5 GO:0048471 perinuclear region of cytoplasm(GO:0048471)
0.0 0.8 GO:0034707 chloride channel complex(GO:0034707)
0.0 0.5 GO:0045271 mitochondrial respiratory chain complex I(GO:0005747) NADH dehydrogenase complex(GO:0030964) respiratory chain complex I(GO:0045271)
0.0 1.1 GO:0005882 intermediate filament(GO:0005882)
0.0 0.4 GO:0005940 septin ring(GO:0005940) septin complex(GO:0031105) septin cytoskeleton(GO:0032156)
0.0 4.3 GO:0031012 extracellular matrix(GO:0031012)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.8 GO:0004329 formate-tetrahydrofolate ligase activity(GO:0004329)
0.2 0.9 GO:0003884 D-amino-acid oxidase activity(GO:0003884)
0.2 1.2 GO:0004392 heme oxygenase (decyclizing) activity(GO:0004392)
0.2 0.9 GO:0019834 phospholipase A2 inhibitor activity(GO:0019834)
0.2 0.5 GO:0031704 apelin receptor binding(GO:0031704)
0.1 4.1 GO:0048306 calcium-dependent protein binding(GO:0048306)
0.1 0.4 GO:0004466 long-chain-acyl-CoA dehydrogenase activity(GO:0004466)
0.1 0.4 GO:0004639 phosphoribosylaminoimidazolesuccinocarboxamide synthase activity(GO:0004639)
0.1 0.5 GO:0015288 porin activity(GO:0015288)
0.1 0.5 GO:0019215 intermediate filament binding(GO:0019215)
0.1 0.7 GO:0043121 neurotrophin binding(GO:0043121)
0.1 0.4 GO:0046592 polyamine oxidase activity(GO:0046592)
0.1 0.2 GO:0001635 adrenomedullin receptor activity(GO:0001605) calcitonin gene-related peptide receptor activity(GO:0001635)
0.1 0.9 GO:0043028 cysteine-type endopeptidase inhibitor activity involved in apoptotic process(GO:0043027) cysteine-type endopeptidase regulator activity involved in apoptotic process(GO:0043028)
0.1 0.3 GO:0005153 interleukin-8 receptor binding(GO:0005153)
0.1 0.3 GO:1990756 protein binding, bridging involved in substrate recognition for ubiquitination(GO:1990756)
0.1 0.4 GO:0034714 type III transforming growth factor beta receptor binding(GO:0034714)
0.1 0.6 GO:0004731 purine-nucleoside phosphorylase activity(GO:0004731)
0.1 0.4 GO:0008349 MAP kinase kinase kinase kinase activity(GO:0008349)
0.1 0.6 GO:0005021 vascular endothelial growth factor-activated receptor activity(GO:0005021)
0.1 0.3 GO:0038132 neuregulin receptor activity(GO:0038131) neuregulin binding(GO:0038132)
0.1 0.5 GO:0004791 thioredoxin-disulfide reductase activity(GO:0004791)
0.0 0.4 GO:0004563 beta-N-acetylhexosaminidase activity(GO:0004563)
0.0 0.3 GO:0031705 bombesin receptor binding(GO:0031705)
0.0 0.2 GO:0005173 stem cell factor receptor binding(GO:0005173)
0.0 0.3 GO:0001641 group II metabotropic glutamate receptor activity(GO:0001641)
0.0 0.3 GO:0035252 UDP-xylosyltransferase activity(GO:0035252)
0.0 0.2 GO:0004903 growth hormone receptor activity(GO:0004903)
0.0 0.1 GO:0070224 sulfide:quinone oxidoreductase activity(GO:0070224)
0.0 0.2 GO:0047192 1-alkylglycerophosphocholine O-acetyltransferase activity(GO:0047192)
0.0 0.8 GO:0005154 epidermal growth factor receptor binding(GO:0005154)
0.0 4.0 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
0.0 0.2 GO:0004385 guanylate kinase activity(GO:0004385)
0.0 1.2 GO:0003823 antigen binding(GO:0003823)
0.0 0.2 GO:0004995 tachykinin receptor activity(GO:0004995)
0.0 1.8 GO:0005200 structural constituent of cytoskeleton(GO:0005200)
0.0 0.3 GO:0004359 glutaminase activity(GO:0004359)
0.0 0.2 GO:0004859 phospholipase inhibitor activity(GO:0004859) lipase inhibitor activity(GO:0055102)
0.0 1.0 GO:0005164 tumor necrosis factor receptor binding(GO:0005164)
0.0 0.3 GO:0016838 carbon-oxygen lyase activity, acting on phosphates(GO:0016838)
0.0 0.6 GO:0080025 phosphatidylinositol-3,5-bisphosphate binding(GO:0080025)
0.0 0.2 GO:0004937 alpha1-adrenergic receptor activity(GO:0004937)
0.0 0.2 GO:0016721 superoxide dismutase activity(GO:0004784) oxidoreductase activity, acting on superoxide radicals as acceptor(GO:0016721)
0.0 0.2 GO:1990380 Lys48-specific deubiquitinase activity(GO:1990380)
0.0 0.3 GO:0015186 L-glutamine transmembrane transporter activity(GO:0015186)
0.0 1.6 GO:0031625 ubiquitin protein ligase binding(GO:0031625)
0.0 0.2 GO:0016316 phosphatidylinositol-3,4-bisphosphate 4-phosphatase activity(GO:0016316)
0.0 0.3 GO:0008503 benzodiazepine receptor activity(GO:0008503) GABA-gated chloride ion channel activity(GO:0022851)
0.0 0.1 GO:0097643 amylin receptor activity(GO:0097643)
0.0 0.8 GO:0005518 collagen binding(GO:0005518)
0.0 0.7 GO:0030165 PDZ domain binding(GO:0030165)
0.0 0.4 GO:0008308 voltage-gated chloride channel activity(GO:0005247) voltage-gated anion channel activity(GO:0008308)
0.0 0.5 GO:0005112 Notch binding(GO:0005112)
0.0 0.2 GO:0003854 3-beta-hydroxy-delta5-steroid dehydrogenase activity(GO:0003854)
0.0 0.3 GO:0008510 sodium:bicarbonate symporter activity(GO:0008510)
0.0 0.2 GO:0004957 prostaglandin E receptor activity(GO:0004957)
0.0 0.7 GO:0005184 neuropeptide hormone activity(GO:0005184)
0.0 0.2 GO:0032977 membrane insertase activity(GO:0032977)
0.0 0.1 GO:0034416 bisphosphoglycerate phosphatase activity(GO:0034416)
0.0 0.1 GO:0016649 electron-transferring-flavoprotein dehydrogenase activity(GO:0004174) oxidoreductase activity, acting on the CH-NH group of donors, quinone or similar compound as acceptor(GO:0016649)
0.0 0.6 GO:0004364 glutathione transferase activity(GO:0004364)
0.0 0.1 GO:0004100 chitin synthase activity(GO:0004100)
0.0 2.4 GO:0004222 metalloendopeptidase activity(GO:0004222)
0.0 0.1 GO:0030548 acetylcholine receptor regulator activity(GO:0030548) neurotransmitter receptor regulator activity(GO:0099602)
0.0 0.6 GO:0017075 syntaxin-1 binding(GO:0017075)
0.0 0.1 GO:0001596 angiotensin type I receptor activity(GO:0001596)
0.0 1.7 GO:0005201 extracellular matrix structural constituent(GO:0005201)
0.0 0.3 GO:0004065 arylsulfatase activity(GO:0004065)
0.0 0.1 GO:0004051 arachidonate 5-lipoxygenase activity(GO:0004051)
0.0 0.1 GO:0015386 monovalent cation:proton antiporter activity(GO:0005451) sodium:proton antiporter activity(GO:0015385) potassium:proton antiporter activity(GO:0015386)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 2.2 PID FRA PATHWAY Validated transcriptional targets of AP1 family members Fra1 and Fra2
0.1 1.0 PID INTEGRIN2 PATHWAY Beta2 integrin cell surface interactions
0.0 0.9 SA CASPASE CASCADE Apoptosis is mediated by caspases, cysteine proteases arranged in a proteolytic cascade.
0.0 0.6 PID ERB GENOMIC PATHWAY Validated nuclear estrogen receptor beta network
0.0 0.8 PID PRL SIGNALING EVENTS PATHWAY Signaling events mediated by PRL
0.0 1.0 PID HES HEY PATHWAY Notch-mediated HES/HEY network
0.0 0.4 PID ALK1 PATHWAY ALK1 signaling events
0.0 0.6 PID TAP63 PATHWAY Validated transcriptional targets of TAp63 isoforms
0.0 0.3 PID NFAT TFPATHWAY Calcineurin-regulated NFAT-dependent transcription in lymphocytes
0.0 0.5 PID HIF1 TFPATHWAY HIF-1-alpha transcription factor network
0.0 1.7 NABA ECM REGULATORS Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.0 0.4 NABA COLLAGENS Genes encoding collagen proteins
0.0 0.4 PID HNF3B PATHWAY FOXA2 and FOXA3 transcription factor networks

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.0 REACTOME DEGRADATION OF THE EXTRACELLULAR MATRIX Genes involved in Degradation of the extracellular matrix
0.1 1.2 REACTOME CS DS DEGRADATION Genes involved in CS/DS degradation
0.1 1.0 REACTOME COMMON PATHWAY Genes involved in Common Pathway
0.1 1.1 REACTOME POST CHAPERONIN TUBULIN FOLDING PATHWAY Genes involved in Post-chaperonin tubulin folding pathway
0.0 0.3 REACTOME GLUTAMATE NEUROTRANSMITTER RELEASE CYCLE Genes involved in Glutamate Neurotransmitter Release Cycle
0.0 0.6 REACTOME RNA POL III CHAIN ELONGATION Genes involved in RNA Polymerase III Chain Elongation
0.0 0.9 REACTOME APOPTOTIC CLEAVAGE OF CELLULAR PROTEINS Genes involved in Apoptotic cleavage of cellular proteins
0.0 0.4 REACTOME METABOLISM OF POLYAMINES Genes involved in Metabolism of polyamines
0.0 0.3 REACTOME THE ACTIVATION OF ARYLSULFATASES Genes involved in The activation of arylsulfatases
0.0 0.4 REACTOME MITOCHONDRIAL FATTY ACID BETA OXIDATION Genes involved in Mitochondrial Fatty Acid Beta-Oxidation
0.0 0.3 REACTOME GABA A RECEPTOR ACTIVATION Genes involved in GABA A receptor activation
0.0 0.2 REACTOME PURINE RIBONUCLEOSIDE MONOPHOSPHATE BIOSYNTHESIS Genes involved in Purine ribonucleoside monophosphate biosynthesis
0.0 0.5 REACTOME REGULATION OF ORNITHINE DECARBOXYLASE ODC Genes involved in Regulation of ornithine decarboxylase (ODC)
0.0 0.2 REACTOME ACYL CHAIN REMODELLING OF PC Genes involved in Acyl chain remodelling of PC
0.0 0.1 REACTOME PHOSPHORYLATION OF CD3 AND TCR ZETA CHAINS Genes involved in Phosphorylation of CD3 and TCR zeta chains
0.0 0.3 REACTOME BMAL1 CLOCK NPAS2 ACTIVATES CIRCADIAN EXPRESSION Genes involved in BMAL1:CLOCK/NPAS2 Activates Circadian Expression
0.0 0.2 REACTOME PTM GAMMA CARBOXYLATION HYPUSINE FORMATION AND ARYLSULFATASE ACTIVATION Genes involved in PTM: gamma carboxylation, hypusine formation and arylsulfatase activation