Project

PRJNA195909:zebrafish embryo and larva development

Navigation
Downloads

Results for irx5a+irx5b_irx3a+irx3b

Z-value: 2.33

Motif logo

Transcription factors associated with irx5a+irx5b_irx3a+irx3b

Gene Symbol Gene ID Gene Info
ENSDARG00000034043 iroquois homeobox 5a
ENSDARG00000074070 iroquois homeobox 5b
ENSDARG00000031138 iroquois homeobox 3b
ENSDARG00000101076 iroquois homeobox 3a

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
irx5adr11_v1_chr7_-_35710263_35710263-0.941.3e-04Click!
irx5bdr11_v1_chr25_+_36152215_36152215-0.924.2e-04Click!
irx3adr11_v1_chr7_+_36035432_36035432-0.891.4e-03Click!
irx3bdr11_v1_chr25_-_36492779_36492779-0.771.6e-02Click!

Activity profile of irx5a+irx5b_irx3a+irx3b motif

Sorted Z-values of irx5a+irx5b_irx3a+irx3b motif

Promoter Log-likelihood Transcript Gene Gene Info
chr23_-_44574059 3.79 ENSDART00000123007
si:ch73-160p18.3
chr15_-_35126332 3.51 ENSDART00000007636
zgc:55413
chr17_+_24809221 3.32 ENSDART00000082251
ENSDART00000147871
ENSDART00000130871
speedy/RINGO cell cycle regulator family member A
chr7_+_34587081 3.01 ENSDART00000173817
formin homology 2 domain containing 1
chr12_+_20693743 2.92 ENSDART00000153023
ENSDART00000153370
ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 1, tandem duplicate 2
chr2_+_205763 2.71 ENSDART00000160164
ENSDART00000101071
zgc:113293
chr16_-_47381519 2.61 ENSDART00000032188
ENSDART00000150136
si:dkey-256h2.1
chr17_-_36860265 2.53 ENSDART00000182786
ENSDART00000193967
SUMO1/sentrin specific peptidase 6b
chr23_+_45845159 2.42 ENSDART00000023944
lamin L3
chr17_+_37310663 2.37 ENSDART00000157122
ELM2 and Myb/SANT-like domain containing 1b
chr8_-_20914829 2.37 ENSDART00000025356
HAUS augmin-like complex, subunit 5
chr20_-_27190393 2.18 ENSDART00000149024
BTB (POZ) domain containing 7
chr19_+_32257472 2.08 ENSDART00000186471
ataxin 1a
chr6_+_33076839 2.04 ENSDART00000073755
ENSDART00000122242
protein O-linked mannose N-acetylglucosaminyltransferase 1 (beta 1,2-)
chr9_-_2945008 2.04 ENSDART00000183452
sterile alpha motif and leucine zipper containing kinase AZK
chr4_-_7869731 1.98 ENSDART00000067339
minichromosome maintenance 10 replication initiation factor
chr7_+_19600262 1.96 ENSDART00000007310
zgc:171731
chr15_+_29472065 1.92 ENSDART00000154343
glycerophosphodiester phosphodiesterase domain containing 5b
chr6_+_18441331 1.90 ENSDART00000171005
si:dkey-31g6.4
chr5_+_66170479 1.90 ENSDART00000172117
glycine dehydrogenase (decarboxylating)
chr10_-_22912255 1.89 ENSDART00000131992
si:ch1073-143l10.2
chr20_+_54299419 1.87 ENSDART00000056089
ENSDART00000193107
si:zfos-1505d6.3
chr21_+_12036238 1.84 ENSDART00000102463
ENSDART00000155426
zgc:162344
chr24_+_12835935 1.81 ENSDART00000114762
nanog homeobox
chr25_-_29072162 1.80 ENSDART00000169269
AT rich interactive domain 3B (BRIGHT-like)
chr17_+_14965570 1.80 ENSDART00000066604
G protein-coupled receptor 137c
chr23_+_45845423 1.79 ENSDART00000183404
lamin L3
chr16_+_25116827 1.78 ENSDART00000163244
si:ch211-261d7.6
chr3_-_26190804 1.77 ENSDART00000136001
yippee-like 3
chr16_+_53259521 1.68 ENSDART00000155461
si:ch211-269k10.5
chr3_+_43774369 1.68 ENSDART00000157964
zinc finger CCCH-type containing 7A
chr21_-_30082414 1.67 ENSDART00000157307
ENSDART00000155188
cyclin J-like
chr12_+_17154655 1.64 ENSDART00000028003
ankyrin repeat domain 22
chr10_+_37400838 1.59 ENSDART00000136554
A kinase (PRKA) anchor protein 1a
chr19_-_2085027 1.58 ENSDART00000063615
sorting nexin 13
chr3_+_33440615 1.58 ENSDART00000146005
GTP binding protein 1
chr15_+_17100412 1.58 ENSDART00000154418
v-rel avian reticuloendotheliosis viral oncogene homolog B
chr8_+_3431671 1.57 ENSDART00000017850
cytosolic thiouridylase subunit 1 homolog (S. pombe)
chr5_-_66429357 1.56 ENSDART00000160189
huntingtin interacting protein 1 related b
chr18_-_12957451 1.55 ENSDART00000140403
SLIT-ROBO Rho GTPase activating protein 1a
chr12_+_13091842 1.49 ENSDART00000185477
ENSDART00000181435
ENSDART00000124799
si:ch211-103b1.2
chr15_+_28175638 1.49 ENSDART00000037119
solute carrier family 46 (folate transporter), member 1
chr7_+_52712807 1.48 ENSDART00000174095
ENSDART00000174377
ENSDART00000174061
ENSDART00000174094
ENSDART00000110906
ENSDART00000174071
ENSDART00000174238
zinc finger protein 280D
chr14_-_26392146 1.48 ENSDART00000037999
xylosylprotein beta 1,4-galactosyltransferase, polypeptide 7 (galactosyltransferase I)
chr2_+_29995590 1.47 ENSDART00000151906
RNA binding motif protein 33b
chr4_-_77116266 1.45 ENSDART00000174249

chr20_+_54034512 1.44 ENSDART00000173226
si:dkey-241l7.2
chr18_+_25546227 1.44 ENSDART00000085824
peroxisomal biogenesis factor 11 alpha
chr6_+_30113750 1.43 ENSDART00000022586
leucine rich repeat containing 40
chr15_-_35112937 1.42 ENSDART00000154565
ENSDART00000099642
zgc:77118
chr7_+_34963748 1.42 ENSDART00000085087
DEAD (Asp-Glu-Ala-Asp) box polypeptide 28
chr22_+_2431585 1.42 ENSDART00000167758
zgc:171435
chr24_-_33308045 1.41 ENSDART00000149711
solute carrier family 4 (anion exchanger), member 2b
chr24_+_32525146 1.41 ENSDART00000132417
ENSDART00000110185
YME1-like 1a
chr20_+_54018005 1.41 ENSDART00000123026
ENSDART00000152894
si:dkey-241l7.5
chr20_+_733510 1.41 ENSDART00000135066
ENSDART00000015558
ENSDART00000152782
myosin VIa
chr6_-_40448416 1.40 ENSDART00000187019
ENSDART00000179469
TatD DNase domain containing 2
chr4_-_77125693 1.39 ENSDART00000174256

chr11_-_8126223 1.38 ENSDART00000091617
ENSDART00000192391
ENSDART00000101561
tubulin tyrosine ligase-like family, member 7
chr20_-_18536474 1.36 ENSDART00000190903
CDC42 binding protein kinase beta (DMPK-like)
chr13_-_86847 1.34 ENSDART00000158062
polymerase (DNA directed), epsilon 2
chr24_-_15263142 1.34 ENSDART00000183176
ENSDART00000006930
rotatin
chr19_-_3876877 1.34 ENSDART00000163711
thyroid hormone receptor associated protein 3b
chr17_+_22311413 1.30 ENSDART00000151929
solute carrier family 8 (sodium/calcium exchanger), member 1b
chr11_-_43473824 1.29 ENSDART00000179561
transmembrane protein 63Bb
chr9_+_23748133 1.29 ENSDART00000180758
Fas apoptotic inhibitory molecule a
chr22_-_5724085 1.27 ENSDART00000110526
ENSDART00000140905
piggyBac transposable element derived 4
chr3_-_402714 1.26 ENSDART00000134062
ENSDART00000105659
major histocompatibility complex class I ZJA
chr7_+_26649319 1.26 ENSDART00000173823
ENSDART00000101053
tumor protein p53 inducible protein 11a
chr15_-_31265375 1.26 ENSDART00000086592
vascular endothelial zinc finger 1b
chr20_+_54024559 1.26 ENSDART00000130767
si:dkey-241l7.4
chr4_-_12781182 1.25 ENSDART00000058020
helicase (DNA) B
chr1_-_34450622 1.24 ENSDART00000083736
LIM domain 7b
chr20_-_48407944 1.24 ENSDART00000085624
importin 13
chr13_+_22717366 1.24 ENSDART00000134122
nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100)
chr20_+_54027943 1.23 ENSDART00000153400
ENSDART00000152961
si:dkey-241l7.3
chr4_-_5691257 1.23 ENSDART00000110497
transmembrane protein 63A
chr5_-_48680580 1.22 ENSDART00000031194
LysM, putative peptidoglycan-binding, domain containing 3
chr12_+_22674030 1.22 ENSDART00000153254
ENSDART00000152930
cell division cycle associated 9
chr10_-_28117740 1.22 ENSDART00000134491
mediator complex subunit 13a
chr12_+_47448558 1.22 ENSDART00000185689
ENSDART00000105328
formin 2b
chr20_+_54024724 1.22 ENSDART00000183562
ENSDART00000152871
si:dkey-241l7.4
chr4_-_77120928 1.21 ENSDART00000174154

chr8_+_42917515 1.21 ENSDART00000021715
solute carrier family 23 (ascorbic acid transporter), member 2
chr18_-_38244871 1.19 ENSDART00000076399
N-acetyltransferase 10
chr16_-_13388821 1.19 ENSDART00000144062
glutamate receptor, ionotropic, N-methyl D-aspartate 2D, b
chr17_-_35076730 1.19 ENSDART00000146590
membrane bound O-acyltransferase domain containing 2a
chr3_-_43954343 1.19 ENSDART00000157580
ubiquitin family domain containing 1
chr18_+_19990412 1.17 ENSDART00000155054
ENSDART00000090310
protein inhibitor of activated STAT, 1b
chr9_+_426392 1.17 ENSDART00000172515
basic leucine zipper and W2 domains 1b
chr20_+_54034677 1.16 ENSDART00000173317
ENSDART00000173215
si:dkey-241l7.2
chr8_+_23034718 1.16 ENSDART00000184512
YTH N(6)-methyladenosine RNA binding protein 1
chr20_+_54027778 1.16 ENSDART00000060458
si:dkey-241l7.3
chr15_+_19324697 1.16 ENSDART00000022015
VPS26 retromer complex component B
chr9_-_20853439 1.15 ENSDART00000028247
ENSDART00000133321
ganglioside induced differentiation associated protein 2
chr21_+_13244450 1.14 ENSDART00000146062
sperm antigen with calponin homology and coiled-coil domains 1-like b
chr10_-_42237304 1.14 ENSDART00000140341
transcription factor 7 like 1a
chr11_-_35970966 1.14 ENSDART00000188805
inositol 1,4,5-trisphosphate receptor, type 1b
chr1_+_50639416 1.14 ENSDART00000141977
HECT and RLD domain containing E3 ubiquitin protein ligase 3
chr18_-_38245062 1.13 ENSDART00000189092
N-acetyltransferase 10
chr16_+_16266428 1.13 ENSDART00000188433
SET domain containing 2
chr8_+_42941555 1.12 ENSDART00000183206
solute carrier family 23 (ascorbic acid transporter), member 2
chr5_-_29152457 1.12 ENSDART00000078469
NADPH oxidase activator 1
chr11_-_42134968 1.11 ENSDART00000187115

chr21_-_45871866 1.11 ENSDART00000161716
La ribonucleoprotein domain family, member 1
chr20_-_25644131 1.10 ENSDART00000138997
si:dkeyp-117h8.4
chr1_+_58602506 1.10 ENSDART00000158425
si:ch73-221f6.1
chr8_-_53044300 1.10 ENSDART00000191653
nuclear receptor subfamily 6, group A, member 1a
chr17_-_13072334 1.10 ENSDART00000159598

chr13_+_12801092 1.09 ENSDART00000164040
ENSDART00000134725
si:ch211-233a24.2
chr21_+_3796196 1.09 ENSDART00000146754
SPOUT domain containing methyltransferase 1
chr25_-_8201983 1.08 ENSDART00000006579
serum amyloid A-like 1
chr22_-_22340688 1.08 ENSDART00000105597
si:ch211-129c21.1
chr12_+_34854562 1.08 ENSDART00000130366
si:dkey-21c1.4
chr1_+_10127163 1.07 ENSDART00000110698
RNA binding motif protein 46
chr3_-_40202607 1.07 ENSDART00000074757
zinc finger protein 598
chr8_+_37749263 1.06 ENSDART00000108556
ENSDART00000147942
nucleophosmin/nucleoplasmin, 2a
chr11_-_37880492 1.06 ENSDART00000102868
ethanolamine kinase 2
chr16_-_7828838 1.06 ENSDART00000191434
ENSDART00000108653
T cell activation inhibitor, mitochondrial
chr7_-_64770456 1.06 ENSDART00000192618
zinc finger, DHHC-type containing 21
chr5_-_58996324 1.05 ENSDART00000033923
MIS12 kinetochore complex component
chr6_-_34838397 1.05 ENSDART00000060169
ENSDART00000169605
mesoderm induction early response 1a, transcriptional regulator
chr9_-_41040492 1.05 ENSDART00000163164
adenosine deaminase, tRNA-specific 3
chr3_+_43102010 1.04 ENSDART00000162096
mical-like 2a
chr22_-_23781083 1.04 ENSDART00000166563
ENSDART00000170458
ENSDART00000166158
ENSDART00000171246
complement factor H like 3
chr17_-_5352924 1.04 ENSDART00000167275
SPT3 homolog, SAGA and STAGA complex component
chr3_+_27606505 1.04 ENSDART00000150953
ubiquitin specific peptidase 7 (herpes virus-associated)
chr16_-_16522013 1.03 ENSDART00000160602
neurobeachin-like 2
chr14_-_10617127 1.02 ENSDART00000154299
si:dkey-92i17.2
chr1_-_34450784 1.02 ENSDART00000140515
LIM domain 7b
chr24_-_33366188 1.00 ENSDART00000074161
solute carrier family 4 (anion exchanger), member 2b
chr18_+_34181655 1.00 ENSDART00000130831
ENSDART00000109535
guanine monophosphate synthase
chr7_-_18877109 1.00 ENSDART00000113593
MLLT3, super elongation complex subunit
chr2_+_27830436 1.00 ENSDART00000182253

chr23_+_34321237 1.00 ENSDART00000173272
plexin A1a
chr25_+_4855549 1.00 ENSDART00000163839
adaptor-related protein complex 4, epsilon 1 subunit
chr7_-_6357952 0.99 ENSDART00000173197
zgc:165555
chr25_+_36292465 0.98 ENSDART00000152649
brambleberry
chr12_-_33789006 0.97 ENSDART00000034550
lethal giant larvae homolog 2 (Drosophila)
chr6_+_32382743 0.97 ENSDART00000190009
dedicator of cytokinesis 7
chr5_+_7279104 0.97 ENSDART00000190014
si:ch73-72b7.1
chr12_+_16087077 0.96 ENSDART00000141898
zinc finger protein 281b
chr17_+_12075805 0.96 ENSDART00000155329
consortin, connexin sorting protein a
chr3_-_45822914 0.96 ENSDART00000155879
si:ch211-66h3.4
chr12_-_5448993 0.95 ENSDART00000181802
TBC1 domain family, member 12b
chr5_-_15264007 0.95 ENSDART00000180641
guanine nucleotide binding protein (G protein), beta polypeptide 1-like
chr9_-_4018452 0.94 ENSDART00000181059
ubiquitin protein ligase E3 component n-recognin 3
chr16_+_3067134 0.92 ENSDART00000012048
cytochrome b5 reductase 4
chr13_-_24825691 0.92 ENSDART00000142745
STE20-like kinase a
chr18_+_14633974 0.92 ENSDART00000133834
VPS9 domain containing 1
chr8_-_1219815 0.92 ENSDART00000016800
ENSDART00000149969
zinc finger protein 367
chr1_-_52210950 0.91 ENSDART00000083946
phospholipase D family, member 6
chr2_-_37532772 0.90 ENSDART00000133951
rho/rac guanine nucleotide exchange factor (GEF) 18a
chr2_-_57900430 0.90 ENSDART00000132245
ENSDART00000140060
si:dkeyp-68b7.7
chr8_-_4760723 0.90 ENSDART00000064201
CDC45 cell division cycle 45 homolog (S. cerevisiae)
chr8_-_40442979 0.89 ENSDART00000157698
ENSDART00000192657
TBC1 domain family, member 10Aa
chr4_+_10604110 0.89 ENSDART00000122636
ENSDART00000037140
inhibitor of growth family, member 3
chr4_+_20486041 0.89 ENSDART00000017572
integrator complex subunit 13
chr11_-_6989598 0.89 ENSDART00000102493
ENSDART00000173242
ENSDART00000172896
zgc:173548
chr25_-_34723937 0.89 ENSDART00000187286
ENSDART00000157021
nucleoporin 160
chr17_+_51746830 0.89 ENSDART00000184230
ornithine decarboxylase 1
chr4_-_6416414 0.88 ENSDART00000191136
si:ch73-156e19.1
chr16_-_24642814 0.88 ENSDART00000153987
ENSDART00000154319
FXYD domain containing ion transport regulator 6 like
chr7_+_70338270 0.87 ENSDART00000065234
glucosidase, beta, acid 3 (gene/pseudogene)
chr21_-_3844322 0.87 ENSDART00000166652
ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 4
chr9_-_1484202 0.87 ENSDART00000181215
RNA binding motif protein 45
chr8_-_11832771 0.87 ENSDART00000193412
ENSDART00000184720
ENSDART00000139947
Rap guanine nucleotide exchange factor (GEF) 1a
chr7_-_6368406 0.86 ENSDART00000172787
histone cluster 1 H2A family member 11
chr19_-_27827744 0.86 ENSDART00000181620
PAP associated domain containing 7
chr6_+_49901465 0.86 ENSDART00000023515
charged multivesicular body protein 4Ba
chr17_+_28675120 0.85 ENSDART00000159067
HECT domain containing 1
chr1_+_51191049 0.85 ENSDART00000132244
ENSDART00000014970
ENSDART00000132141
BTB (POZ) domain containing 3a
chr14_-_8940499 0.85 ENSDART00000129030
zgc:153681
chr16_+_16265850 0.85 ENSDART00000181265
SET domain containing 2
chr19_+_26340736 0.84 ENSDART00000013497
myosin regulatory light chain interacting protein a
chr23_+_42131509 0.83 ENSDART00000184544
shisa like 2A
chr25_-_36263115 0.83 ENSDART00000143046
ENSDART00000139002
dihydrouridine synthase 2
chr4_-_20313810 0.83 ENSDART00000136350
decapping mRNA 1B
chr24_-_26981848 0.83 ENSDART00000183198
stromal antigen 1b
chr19_-_7043355 0.83 ENSDART00000104845
TAP binding protein (tapasin), tandem duplicate 1
chr25_-_17590971 0.82 ENSDART00000189942
matrix metallopeptidase 15a
chr13_+_24671481 0.82 ENSDART00000001678
ADAM metallopeptidase domain 8a
chr25_+_6266009 0.82 ENSDART00000148995
solute carrier family 25, member 44 a
chr23_-_3721444 0.81 ENSDART00000141682
nudix (nucleoside diphosphate linked moiety X)-type motif 3a
chr9_+_24088062 0.81 ENSDART00000126198
leucine rich repeat (in FLII) interacting protein 1a
chr6_-_28961660 0.81 ENSDART00000147285
translocase of outer mitochondrial membrane 70 homolog A (S. cerevisiae)
chr3_+_18050667 0.81 ENSDART00000035531
methyltransferase like 26
chr13_+_6092135 0.80 ENSDART00000162738
family with sequence similarity 120B
chr16_+_29516098 0.80 ENSDART00000174895
cathepsin S, ortholog 2, tandem duplicate 2
chr23_-_33680265 0.80 ENSDART00000138416
transcription factor CP2
chr23_+_29885019 0.79 ENSDART00000167059
aurora kinase A interacting protein 1
chr2_-_29923403 0.79 ENSDART00000144672
PAX interacting (with transcription-activation domain) protein 1
chr13_-_25719628 0.79 ENSDART00000135383
si:dkey-192p21.6
chr18_-_44847855 0.79 ENSDART00000086823
signal recognition particle receptor (docking protein)
chr2_-_43850897 0.79 ENSDART00000005449
zinc finger E-box binding homeobox 1a
chr23_-_19977214 0.79 ENSDART00000054659
cyclin Q
chr14_+_17397534 0.79 ENSDART00000180162
ENSDART00000129838
ring finger protein 212
chr4_-_9191220 0.79 ENSDART00000156919
host cell factor C2
chr1_+_46404968 0.79 ENSDART00000042064
tubulin, gamma complex associated protein 3
chr13_-_24745288 0.78 ENSDART00000031564
SWI5-dependent homologous recombination repair protein 1

Network of associatons between targets according to the STRING database.

First level regulatory network of irx5a+irx5b_irx3a+irx3b

PNG image of the network

In order to view interactive SVG image please either update your browser to latest version or install SVG plugin.


View svg image
View png image

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.8 2.3 GO:0015882 L-ascorbic acid transport(GO:0015882) L-ascorbic acid metabolic process(GO:0019852)
0.7 2.0 GO:0061668 mitochondrial ribosome assembly(GO:0061668)
0.6 2.5 GO:0090230 regulation of centromere complex assembly(GO:0090230) regulation of kinetochore assembly(GO:0090234)
0.5 1.6 GO:0010657 negative regulation of muscle cell apoptotic process(GO:0010656) muscle cell apoptotic process(GO:0010657) striated muscle cell apoptotic process(GO:0010658) regulation of muscle cell apoptotic process(GO:0010660) regulation of striated muscle cell apoptotic process(GO:0010662) negative regulation of striated muscle cell apoptotic process(GO:0010664)
0.5 1.9 GO:0019464 glycine catabolic process(GO:0006546) glycine decarboxylation via glycine cleavage system(GO:0019464)
0.4 1.1 GO:0097095 frontonasal suture morphogenesis(GO:0097095)
0.4 1.9 GO:0039689 viral genome replication(GO:0019079) negative stranded viral RNA replication(GO:0039689) viral RNA genome replication(GO:0039694) RNA replication(GO:0039703) multi-organism biosynthetic process(GO:0044034)
0.4 1.1 GO:0072344 rescue of stalled ribosome(GO:0072344)
0.3 2.0 GO:0097198 histone H3-K36 trimethylation(GO:0097198)
0.3 1.0 GO:0090004 positive regulation of Golgi to plasma membrane protein transport(GO:0042998) positive regulation of establishment of protein localization to plasma membrane(GO:0090004)
0.3 0.9 GO:1902001 regulation of plasma membrane long-chain fatty acid transport(GO:0010746) positive regulation of plasma membrane long-chain fatty acid transport(GO:0010747) plasma membrane long-chain fatty acid transport(GO:0015911) fatty acid transmembrane transport(GO:1902001) positive regulation of anion transmembrane transport(GO:1903961) regulation of fatty acid transport(GO:2000191) positive regulation of fatty acid transport(GO:2000193)
0.3 1.3 GO:0006269 DNA replication, synthesis of RNA primer(GO:0006269)
0.3 2.0 GO:0016266 O-glycan processing(GO:0016266)
0.3 1.7 GO:0010457 centriole-centriole cohesion(GO:0010457)
0.3 1.1 GO:0060829 negative regulation of canonical Wnt signaling pathway involved in neural plate anterior/posterior pattern formation(GO:0060829)
0.3 1.4 GO:0008594 photoreceptor cell morphogenesis(GO:0008594) negative regulation of epithelial to mesenchymal transition(GO:0010719)
0.3 0.8 GO:0051044 positive regulation of membrane protein ectodomain proteolysis(GO:0051044)
0.3 1.1 GO:0051661 maintenance of centrosome location(GO:0051661)
0.3 1.1 GO:0042776 mitochondrial ATP synthesis coupled proton transport(GO:0042776)
0.3 1.6 GO:0032447 tRNA wobble position uridine thiolation(GO:0002143) protein urmylation(GO:0032447)
0.3 1.0 GO:0036344 platelet formation(GO:0030220) platelet morphogenesis(GO:0036344)
0.2 0.7 GO:0043654 recognition of apoptotic cell(GO:0043654)
0.2 0.7 GO:0010526 regulation of transposition, RNA-mediated(GO:0010525) negative regulation of transposition, RNA-mediated(GO:0010526) transposition, RNA-mediated(GO:0032197) positive regulation of neuron apoptotic process(GO:0043525) positive regulation of neuron death(GO:1901216)
0.2 1.4 GO:0016559 peroxisome fission(GO:0016559)
0.2 0.7 GO:0010452 histone H3-K36 methylation(GO:0010452)
0.2 0.7 GO:0001692 histamine metabolic process(GO:0001692)
0.2 1.1 GO:0010692 regulation of alkaline phosphatase activity(GO:0010692) negative regulation of alkaline phosphatase activity(GO:0010693)
0.2 1.9 GO:0042276 error-prone translesion synthesis(GO:0042276)
0.2 0.6 GO:1902767 farnesyl diphosphate biosynthetic process, mevalonate pathway(GO:0010142) isoprenoid biosynthetic process via mevalonate(GO:1902767)
0.2 1.0 GO:0000741 karyogamy(GO:0000741) pronuclear fusion(GO:0007344)
0.2 0.9 GO:0071596 ubiquitin-dependent protein catabolic process via the N-end rule pathway(GO:0071596)
0.2 2.0 GO:1902041 regulation of extrinsic apoptotic signaling pathway via death domain receptors(GO:1902041) negative regulation of extrinsic apoptotic signaling pathway via death domain receptors(GO:1902042)
0.2 1.5 GO:0006348 chromatin silencing at telomere(GO:0006348)
0.2 0.8 GO:1901908 diphosphoinositol polyphosphate metabolic process(GO:0071543) diadenosine pentaphosphate metabolic process(GO:1901906) diadenosine pentaphosphate catabolic process(GO:1901907) diadenosine hexaphosphate metabolic process(GO:1901908) diadenosine hexaphosphate catabolic process(GO:1901909) adenosine 5'-(hexahydrogen pentaphosphate) metabolic process(GO:1901910) adenosine 5'-(hexahydrogen pentaphosphate) catabolic process(GO:1901911)
0.2 0.5 GO:0090141 positive regulation of mitochondrial fission(GO:0090141)
0.2 0.3 GO:0097094 craniofacial suture morphogenesis(GO:0097094)
0.2 0.5 GO:0006359 regulation of transcription from RNA polymerase III promoter(GO:0006359)
0.1 1.8 GO:1904263 positive regulation of TORC1 signaling(GO:1904263)
0.1 0.4 GO:0030213 hyaluronan biosynthetic process(GO:0030213)
0.1 0.7 GO:0031053 primary miRNA processing(GO:0031053)
0.1 1.7 GO:0035196 production of miRNAs involved in gene silencing by miRNA(GO:0035196)
0.1 1.1 GO:0042554 superoxide anion generation(GO:0042554)
0.1 0.6 GO:0099563 modification of synaptic structure(GO:0099563)
0.1 0.8 GO:0031086 nuclear-transcribed mRNA catabolic process, deadenylation-independent decay(GO:0031086) deadenylation-independent decapping of nuclear-transcribed mRNA(GO:0031087)
0.1 2.3 GO:2000369 regulation of clathrin-mediated endocytosis(GO:2000369)
0.1 2.1 GO:0010738 regulation of protein kinase A signaling(GO:0010738)
0.1 3.0 GO:0051639 actin filament network formation(GO:0051639)
0.1 0.5 GO:0030890 B cell homeostasis(GO:0001782) positive regulation of B cell proliferation(GO:0030890)
0.1 0.4 GO:0043968 histone H2A acetylation(GO:0043968)
0.1 0.5 GO:0046900 tetrahydrofolylpolyglutamate metabolic process(GO:0046900)
0.1 1.8 GO:0035278 miRNA mediated inhibition of translation(GO:0035278) negative regulation of translation, ncRNA-mediated(GO:0040033) regulation of translation, ncRNA-mediated(GO:0045974)
0.1 0.7 GO:0033169 histone H3-K9 demethylation(GO:0033169)
0.1 1.7 GO:0000479 endonucleolytic cleavage involved in rRNA processing(GO:0000478) endonucleolytic cleavage of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000479)
0.1 0.9 GO:0042138 meiotic DNA double-strand break formation(GO:0042138)
0.1 2.0 GO:0015693 magnesium ion transport(GO:0015693)
0.1 0.6 GO:0070587 regulation of cell-cell adhesion involved in gastrulation(GO:0070587)
0.1 1.0 GO:0000185 activation of MAPKKK activity(GO:0000185)
0.1 1.4 GO:0051382 kinetochore assembly(GO:0051382)
0.1 0.5 GO:0045843 negative regulation of striated muscle tissue development(GO:0045843) negative regulation of muscle tissue development(GO:1901862)
0.1 0.7 GO:0034975 protein folding in endoplasmic reticulum(GO:0034975)
0.1 0.6 GO:0016094 polyprenol biosynthetic process(GO:0016094)
0.1 0.9 GO:0046477 glycosylceramide catabolic process(GO:0046477)
0.1 0.8 GO:0043154 negative regulation of cysteine-type endopeptidase activity involved in apoptotic process(GO:0043154)
0.1 0.5 GO:2000781 positive regulation of double-strand break repair(GO:2000781)
0.1 2.5 GO:0015701 bicarbonate transport(GO:0015701)
0.1 1.1 GO:0043984 histone H4-K16 acetylation(GO:0043984)
0.1 0.5 GO:0071480 response to gamma radiation(GO:0010332) cellular response to gamma radiation(GO:0071480)
0.1 0.9 GO:0051673 membrane disruption in other organism(GO:0051673)
0.1 3.2 GO:0000154 rRNA modification(GO:0000154)
0.1 1.2 GO:0061157 RNA destabilization(GO:0050779) mRNA destabilization(GO:0061157)
0.1 0.1 GO:0006168 adenine salvage(GO:0006168)
0.1 0.8 GO:0055015 ventricular cardiac muscle cell development(GO:0055015)
0.1 0.5 GO:0000002 mitochondrial genome maintenance(GO:0000002) mitochondrial DNA replication(GO:0006264) mitochondrial DNA metabolic process(GO:0032042)
0.1 1.5 GO:0031468 nuclear envelope reassembly(GO:0031468)
0.1 0.9 GO:0033387 putrescine biosynthetic process from ornithine(GO:0033387)
0.1 0.3 GO:0071586 CAAX-box protein processing(GO:0071586) CAAX-box protein maturation(GO:0080120)
0.1 0.5 GO:0000738 DNA catabolic process, exonucleolytic(GO:0000738)
0.1 1.5 GO:0008053 mitochondrial fusion(GO:0008053)
0.1 0.5 GO:0003232 bulbus arteriosus development(GO:0003232)
0.1 0.4 GO:1903019 negative regulation of glycoprotein biosynthetic process(GO:0010561) negative regulation of amyloid precursor protein biosynthetic process(GO:0042985) negative regulation of glycoprotein metabolic process(GO:1903019)
0.1 0.4 GO:0051876 pigment granule dispersal(GO:0051876)
0.1 0.4 GO:0032782 canalicular bile acid transport(GO:0015722) bile acid secretion(GO:0032782)
0.1 0.3 GO:0030238 female sex determination(GO:0030237) male sex determination(GO:0030238)
0.1 0.5 GO:0006166 purine ribonucleoside salvage(GO:0006166)
0.1 0.7 GO:0006478 protein sulfation(GO:0006477) peptidyl-tyrosine sulfation(GO:0006478)
0.1 1.0 GO:0038007 netrin-activated signaling pathway(GO:0038007)
0.1 0.7 GO:0006203 dGTP catabolic process(GO:0006203) purine nucleoside triphosphate catabolic process(GO:0009146) purine deoxyribonucleoside triphosphate catabolic process(GO:0009217) dGTP metabolic process(GO:0046070)
0.1 0.6 GO:0043201 response to leucine(GO:0043201) cellular response to leucine(GO:0071233) regulation of response to reactive oxygen species(GO:1901031)
0.1 1.1 GO:0034244 negative regulation of DNA-templated transcription, elongation(GO:0032785) negative regulation of transcription elongation from RNA polymerase II promoter(GO:0034244)
0.1 0.3 GO:0042256 mature ribosome assembly(GO:0042256) assembly of large subunit precursor of preribosome(GO:1902626)
0.1 0.4 GO:0007252 I-kappaB phosphorylation(GO:0007252)
0.1 2.4 GO:0016925 protein sumoylation(GO:0016925)
0.1 0.4 GO:0014005 microglia development(GO:0014005)
0.1 0.4 GO:0032289 central nervous system myelin formation(GO:0032289)
0.1 1.5 GO:0006801 superoxide metabolic process(GO:0006801)
0.1 0.5 GO:0000393 spliceosomal conformational changes to generate catalytic conformation(GO:0000393)
0.1 1.3 GO:0007020 microtubule nucleation(GO:0007020)
0.1 0.3 GO:0032207 regulation of telomere maintenance via recombination(GO:0032207) negative regulation of telomere maintenance via recombination(GO:0032208)
0.1 1.1 GO:2000785 regulation of autophagosome assembly(GO:2000785)
0.1 0.8 GO:0002483 antigen processing and presentation of endogenous peptide antigen(GO:0002483) antigen processing and presentation of endogenous antigen(GO:0019883) antigen processing and presentation of endogenous peptide antigen via MHC class I(GO:0019885)
0.1 0.5 GO:0003188 heart valve formation(GO:0003188) atrioventricular valve formation(GO:0003190)
0.1 1.0 GO:0051123 RNA polymerase II transcriptional preinitiation complex assembly(GO:0051123)
0.1 0.2 GO:0043455 regulation of secondary metabolic process(GO:0043455)
0.1 0.4 GO:0006384 transcription initiation from RNA polymerase III promoter(GO:0006384)
0.1 0.3 GO:0070199 establishment of mitotic sister chromatid cohesion(GO:0034087) establishment of protein localization to chromosome(GO:0070199) establishment of protein localization to chromatin(GO:0071169) transcriptional activation by promoter-enhancer looping(GO:0071733) gene looping(GO:0090202) dsDNA loop formation(GO:0090579)
0.1 0.3 GO:0070291 N-acylethanolamine metabolic process(GO:0070291)
0.1 0.6 GO:0044090 positive regulation of vacuole organization(GO:0044090)
0.1 1.0 GO:0032008 positive regulation of TOR signaling(GO:0032008)
0.1 0.3 GO:2000815 regulation of mRNA stability involved in response to stress(GO:0010610) regulation of mRNA stability involved in response to oxidative stress(GO:2000815)
0.1 0.3 GO:0090076 regulation of twitch skeletal muscle contraction(GO:0014724) regulation of fast-twitch skeletal muscle fiber contraction(GO:0031446) positive regulation of fast-twitch skeletal muscle fiber contraction(GO:0031448) negative regulation of striated muscle contraction(GO:0045988) relaxation of skeletal muscle(GO:0090076)
0.1 1.4 GO:0098703 calcium ion import across plasma membrane(GO:0098703) calcium ion import into cell(GO:1990035)
0.1 0.9 GO:0051642 centrosome localization(GO:0051642)
0.1 0.2 GO:0070358 actin polymerization-dependent cell motility(GO:0070358)
0.1 0.8 GO:0050909 sensory perception of taste(GO:0050909)
0.1 0.6 GO:0098789 mRNA cleavage involved in mRNA processing(GO:0098787) pre-mRNA cleavage required for polyadenylation(GO:0098789)
0.1 0.3 GO:1902165 regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator(GO:1902165)
0.1 0.4 GO:0006596 polyamine biosynthetic process(GO:0006596)
0.1 0.7 GO:0046037 GMP biosynthetic process(GO:0006177) GMP metabolic process(GO:0046037)
0.1 0.7 GO:0006032 chitin catabolic process(GO:0006032)
0.1 0.5 GO:0031106 septin ring organization(GO:0031106) septin cytoskeleton organization(GO:0032185)
0.1 0.6 GO:0010569 regulation of double-strand break repair via homologous recombination(GO:0010569)
0.1 0.4 GO:0021529 spinal cord oligodendrocyte cell differentiation(GO:0021529)
0.1 1.4 GO:0048844 artery morphogenesis(GO:0048844)
0.1 1.2 GO:0060079 excitatory postsynaptic potential(GO:0060079)
0.1 0.6 GO:0006450 regulation of translational fidelity(GO:0006450)
0.1 0.7 GO:0070979 protein K11-linked ubiquitination(GO:0070979)
0.1 0.3 GO:0097037 heme export(GO:0097037)
0.1 0.9 GO:0071156 regulation of cell cycle arrest(GO:0071156)
0.1 1.3 GO:1901888 regulation of cell junction assembly(GO:1901888)
0.1 2.1 GO:0061138 morphogenesis of a branching epithelium(GO:0061138)
0.1 0.3 GO:0043508 negative regulation of JUN kinase activity(GO:0043508)
0.1 0.7 GO:1900052 regulation of isoprenoid metabolic process(GO:0019747) regulation of vitamin metabolic process(GO:0030656) regulation of retinoic acid biosynthetic process(GO:1900052)
0.1 0.7 GO:0033198 response to ATP(GO:0033198)
0.1 1.7 GO:0038061 NIK/NF-kappaB signaling(GO:0038061)
0.1 0.6 GO:0006382 adenosine to inosine editing(GO:0006382)
0.1 0.4 GO:0070285 pigment cell development(GO:0070285)
0.1 1.4 GO:0006303 double-strand break repair via nonhomologous end joining(GO:0006303)
0.1 1.4 GO:0006515 misfolded or incompletely synthesized protein catabolic process(GO:0006515)
0.1 1.7 GO:0006270 DNA replication initiation(GO:0006270)
0.1 0.2 GO:1904478 regulation of intestinal absorption(GO:1904478) regulation of intestinal lipid absorption(GO:1904729)
0.1 0.4 GO:0032732 positive regulation of interleukin-1 production(GO:0032732)
0.1 3.3 GO:0007098 centrosome cycle(GO:0007098) centrosome organization(GO:0051297)
0.1 0.6 GO:0050892 intestinal absorption(GO:0050892)
0.1 0.5 GO:0051877 pigment granule aggregation in cell center(GO:0051877)
0.0 0.7 GO:0000460 maturation of 5.8S rRNA(GO:0000460)
0.0 2.6 GO:0031122 cytoplasmic microtubule organization(GO:0031122)
0.0 0.2 GO:0097039 protein linear polyubiquitination(GO:0097039)
0.0 0.6 GO:0042661 regulation of mesodermal cell fate specification(GO:0042661)
0.0 0.2 GO:0030219 megakaryocyte differentiation(GO:0030219)
0.0 0.6 GO:0051865 protein autoubiquitination(GO:0051865)
0.0 0.2 GO:0097510 base-excision repair, AP site formation via deaminated base removal(GO:0097510)
0.0 0.9 GO:1902285 semaphorin-plexin signaling pathway involved in neuron projection guidance(GO:1902285) semaphorin-plexin signaling pathway involved in axon guidance(GO:1902287)
0.0 0.5 GO:0006611 protein export from nucleus(GO:0006611)
0.0 1.5 GO:0043966 histone H3 acetylation(GO:0043966)
0.0 0.2 GO:0098529 neuromuscular junction development, skeletal muscle fiber(GO:0098529)
0.0 1.0 GO:0006298 mismatch repair(GO:0006298)
0.0 0.4 GO:0038203 TORC2 signaling(GO:0038203)
0.0 0.1 GO:0019695 choline metabolic process(GO:0019695)
0.0 0.2 GO:0001836 release of cytochrome c from mitochondria(GO:0001836)
0.0 0.6 GO:0060236 regulation of mitotic spindle organization(GO:0060236)
0.0 0.1 GO:0048785 hatching gland development(GO:0048785)
0.0 0.4 GO:0043928 exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay(GO:0043928)
0.0 0.5 GO:0036353 histone H2A monoubiquitination(GO:0035518) histone H2A-K119 monoubiquitination(GO:0036353)
0.0 0.3 GO:0006301 postreplication repair(GO:0006301)
0.0 0.2 GO:0006788 heme oxidation(GO:0006788)
0.0 0.4 GO:0006685 sphingomyelin catabolic process(GO:0006685)
0.0 1.1 GO:0016601 Rac protein signal transduction(GO:0016601)
0.0 0.7 GO:0018095 protein polyglutamylation(GO:0018095)
0.0 0.1 GO:0048205 COPI-coated vesicle budding(GO:0035964) Golgi transport vesicle coating(GO:0048200) COPI coating of Golgi vesicle(GO:0048205)
0.0 0.8 GO:0038092 nodal signaling pathway(GO:0038092)
0.0 0.4 GO:0015721 bile acid and bile salt transport(GO:0015721)
0.0 0.1 GO:0070084 protein initiator methionine removal(GO:0070084)
0.0 0.0 GO:1901407 regulation of phosphorylation of RNA polymerase II C-terminal domain(GO:1901407)
0.0 0.3 GO:0043435 response to corticotropin-releasing hormone(GO:0043435) cellular response to corticotropin-releasing hormone stimulus(GO:0071376)
0.0 0.3 GO:0060999 positive regulation of dendritic spine development(GO:0060999)
0.0 0.2 GO:0016572 histone phosphorylation(GO:0016572)
0.0 0.6 GO:0035308 negative regulation of dephosphorylation(GO:0035305) negative regulation of protein dephosphorylation(GO:0035308)
0.0 0.4 GO:0071850 mitotic cell cycle arrest(GO:0071850)
0.0 0.2 GO:0032793 positive regulation of CREB transcription factor activity(GO:0032793)
0.0 0.4 GO:2001057 reactive nitrogen species metabolic process(GO:2001057)
0.0 0.1 GO:0010447 response to acidic pH(GO:0010447)
0.0 0.4 GO:0006998 nuclear envelope organization(GO:0006998)
0.0 0.2 GO:0006011 UDP-glucose metabolic process(GO:0006011)
0.0 0.5 GO:0048096 chromatin-mediated maintenance of transcription(GO:0048096)
0.0 0.1 GO:0097053 L-kynurenine metabolic process(GO:0097052) L-kynurenine catabolic process(GO:0097053)
0.0 0.8 GO:0043666 regulation of phosphoprotein phosphatase activity(GO:0043666)
0.0 0.1 GO:0090387 phagosome maturation involved in apoptotic cell clearance(GO:0090386) phagolysosome assembly involved in apoptotic cell clearance(GO:0090387)
0.0 0.2 GO:0060049 regulation of protein glycosylation(GO:0060049)
0.0 1.6 GO:0006414 translational elongation(GO:0006414)
0.0 0.3 GO:0008625 extrinsic apoptotic signaling pathway via death domain receptors(GO:0008625)
0.0 0.6 GO:1990126 retrograde transport, endosome to plasma membrane(GO:1990126)
0.0 1.8 GO:0030166 proteoglycan biosynthetic process(GO:0030166)
0.0 0.4 GO:0001574 ganglioside biosynthetic process(GO:0001574)
0.0 0.2 GO:0019563 glycerol catabolic process(GO:0019563)
0.0 0.2 GO:0018344 protein geranylgeranylation(GO:0018344)
0.0 0.1 GO:1990173 nuclear body organization(GO:0030575) Cajal body organization(GO:0030576) protein localization to nuclear body(GO:1903405) protein localization to Cajal body(GO:1904867) protein localization to nucleoplasm(GO:1990173)
0.0 0.5 GO:0002115 store-operated calcium entry(GO:0002115)
0.0 1.2 GO:0032011 ARF protein signal transduction(GO:0032011) regulation of ARF protein signal transduction(GO:0032012)
0.0 0.7 GO:0070536 protein K63-linked deubiquitination(GO:0070536)
0.0 0.2 GO:0034080 chromatin remodeling at centromere(GO:0031055) CENP-A containing nucleosome assembly(GO:0034080) CENP-A containing chromatin organization(GO:0061641)
0.0 0.9 GO:0070534 protein K63-linked ubiquitination(GO:0070534)
0.0 1.6 GO:0016575 histone deacetylation(GO:0016575)
0.0 1.0 GO:0031647 regulation of protein stability(GO:0031647)
0.0 0.6 GO:0071542 dopaminergic neuron differentiation(GO:0071542)
0.0 0.2 GO:0045943 positive regulation of transcription from RNA polymerase I promoter(GO:0045943)
0.0 0.5 GO:0018401 peptidyl-proline hydroxylation to 4-hydroxy-L-proline(GO:0018401) 4-hydroxyproline metabolic process(GO:0019471)
0.0 0.2 GO:0035552 oxidative single-stranded DNA demethylation(GO:0035552)
0.0 0.3 GO:0009263 deoxyribonucleotide biosynthetic process(GO:0009263)
0.0 0.8 GO:0044243 collagen catabolic process(GO:0030574) multicellular organism catabolic process(GO:0044243)
0.0 0.6 GO:0021591 ventricular system development(GO:0021591)
0.0 2.1 GO:0000724 double-strand break repair via homologous recombination(GO:0000724)
0.0 0.8 GO:0030488 tRNA methylation(GO:0030488)
0.0 2.0 GO:0007030 Golgi organization(GO:0007030)
0.0 1.9 GO:0034504 protein localization to nucleus(GO:0034504)
0.0 1.4 GO:0018107 peptidyl-threonine phosphorylation(GO:0018107)
0.0 0.5 GO:0045841 mitotic spindle assembly checkpoint(GO:0007094) spindle checkpoint(GO:0031577) negative regulation of mitotic metaphase/anaphase transition(GO:0045841) spindle assembly checkpoint(GO:0071173) mitotic spindle checkpoint(GO:0071174)
0.0 0.3 GO:0051121 lipoxygenase pathway(GO:0019372) linoleic acid metabolic process(GO:0043651) hepoxilin metabolic process(GO:0051121) hepoxilin biosynthetic process(GO:0051122)
0.0 0.1 GO:0031340 positive regulation of vesicle fusion(GO:0031340)
0.0 0.5 GO:0007257 activation of JUN kinase activity(GO:0007257) regulation of JUN kinase activity(GO:0043506) positive regulation of JUN kinase activity(GO:0043507)
0.0 0.8 GO:0007062 sister chromatid cohesion(GO:0007062)
0.0 0.9 GO:0042752 regulation of circadian rhythm(GO:0042752)
0.0 0.2 GO:0070836 membrane raft assembly(GO:0001765) plasma membrane raft assembly(GO:0044854) plasma membrane raft organization(GO:0044857) caveola assembly(GO:0070836)
0.0 0.5 GO:0046475 glycerophospholipid catabolic process(GO:0046475)
0.0 0.2 GO:0071294 cellular response to zinc ion(GO:0071294)
0.0 0.3 GO:0046470 phosphatidylcholine metabolic process(GO:0046470)
0.0 0.5 GO:0006282 regulation of DNA repair(GO:0006282)
0.0 0.7 GO:1902036 regulation of hematopoietic stem cell differentiation(GO:1902036)
0.0 0.6 GO:0006284 base-excision repair(GO:0006284)
0.0 0.1 GO:0032790 ribosome disassembly(GO:0032790)
0.0 0.3 GO:0045910 negative regulation of DNA recombination(GO:0045910)
0.0 0.3 GO:0098734 protein depalmitoylation(GO:0002084) macromolecule depalmitoylation(GO:0098734)
0.0 0.2 GO:0045948 positive regulation of translational initiation(GO:0045948)
0.0 1.1 GO:0042147 retrograde transport, endosome to Golgi(GO:0042147)
0.0 0.4 GO:0030183 B cell differentiation(GO:0030183)
0.0 2.2 GO:0090630 activation of GTPase activity(GO:0090630)
0.0 0.3 GO:0045920 negative regulation of exocytosis(GO:0045920)
0.0 0.1 GO:0072677 eosinophil chemotaxis(GO:0048245) eosinophil migration(GO:0072677)
0.0 0.9 GO:0000070 mitotic sister chromatid segregation(GO:0000070)
0.0 0.9 GO:0000245 spliceosomal complex assembly(GO:0000245)
0.0 1.6 GO:0035023 regulation of Rho protein signal transduction(GO:0035023)
0.0 0.4 GO:0009950 dorsal/ventral axis specification(GO:0009950)
0.0 0.4 GO:0006406 mRNA export from nucleus(GO:0006406) mRNA-containing ribonucleoprotein complex export from nucleus(GO:0071427)
0.0 0.1 GO:0000706 meiotic DNA double-strand break processing(GO:0000706)
0.0 0.0 GO:1903430 regulation of oocyte maturation(GO:1900193) negative regulation of cell maturation(GO:1903430)
0.0 0.7 GO:0051016 barbed-end actin filament capping(GO:0051016)
0.0 0.2 GO:0021694 cerebellar Purkinje cell layer formation(GO:0021694) cerebellar Purkinje cell differentiation(GO:0021702)
0.0 0.2 GO:0045022 early endosome to late endosome transport(GO:0045022) vesicle-mediated transport between endosomal compartments(GO:0098927)
0.0 1.2 GO:0032147 activation of protein kinase activity(GO:0032147)
0.0 0.8 GO:0045010 actin nucleation(GO:0045010)
0.0 0.2 GO:0070936 protein K48-linked ubiquitination(GO:0070936)
0.0 1.7 GO:0006338 chromatin remodeling(GO:0006338)
0.0 0.6 GO:0030968 endoplasmic reticulum unfolded protein response(GO:0030968)
0.0 1.1 GO:0031497 chromatin assembly(GO:0031497)
0.0 0.1 GO:0032781 positive regulation of ATPase activity(GO:0032781)
0.0 0.5 GO:0051209 release of sequestered calcium ion into cytosol(GO:0051209)
0.0 0.2 GO:0030325 adrenal gland development(GO:0030325)
0.0 0.2 GO:0098962 regulation of postsynaptic neurotransmitter receptor activity(GO:0098962)
0.0 1.1 GO:0007179 transforming growth factor beta receptor signaling pathway(GO:0007179) response to transforming growth factor beta(GO:0071559) cellular response to transforming growth factor beta stimulus(GO:0071560)
0.0 0.7 GO:0090263 positive regulation of canonical Wnt signaling pathway(GO:0090263)
0.0 0.2 GO:0002574 thrombocyte differentiation(GO:0002574)
0.0 0.1 GO:0006488 dolichol-linked oligosaccharide biosynthetic process(GO:0006488)
0.0 0.8 GO:0030917 midbrain-hindbrain boundary development(GO:0030917)
0.0 0.1 GO:0038083 peptidyl-tyrosine autophosphorylation(GO:0038083)
0.0 0.1 GO:0036297 interstrand cross-link repair(GO:0036297)
0.0 1.5 GO:0006281 DNA repair(GO:0006281)
0.0 0.2 GO:0060323 head morphogenesis(GO:0060323)
0.0 0.6 GO:0048488 synaptic vesicle endocytosis(GO:0048488)
0.0 0.2 GO:0032958 inositol phosphate biosynthetic process(GO:0032958)
0.0 0.9 GO:0006487 protein N-linked glycosylation(GO:0006487)
0.0 0.6 GO:0031146 SCF-dependent proteasomal ubiquitin-dependent protein catabolic process(GO:0031146)
0.0 0.2 GO:0021986 habenula development(GO:0021986)
0.0 0.2 GO:0006446 regulation of translational initiation(GO:0006446)
0.0 0.5 GO:0014046 dopamine secretion(GO:0014046) regulation of dopamine secretion(GO:0014059)
0.0 0.3 GO:0006828 manganese ion transport(GO:0006828)
0.0 0.4 GO:0021549 cerebellum development(GO:0021549)
0.0 0.2 GO:0008089 anterograde axonal transport(GO:0008089)
0.0 0.9 GO:0016579 protein deubiquitination(GO:0016579)
0.0 0.0 GO:0046931 pore complex assembly(GO:0046931)
0.0 0.4 GO:0006400 tRNA modification(GO:0006400)
0.0 0.4 GO:0048813 dendrite morphogenesis(GO:0048813)
0.0 0.4 GO:0006626 protein targeting to mitochondrion(GO:0006626)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 1.9 GO:0005960 glycine cleavage complex(GO:0005960)
0.4 1.3 GO:0008275 gamma-tubulin small complex(GO:0008275)
0.4 2.0 GO:0031298 replication fork protection complex(GO:0031298)
0.4 0.4 GO:0000126 transcription factor TFIIIB complex(GO:0000126)
0.3 1.3 GO:0008622 epsilon DNA polymerase complex(GO:0008622)
0.3 0.8 GO:0071065 alpha9-beta1 integrin-vascular cell adhesion molecule-1 complex(GO:0071065)
0.3 1.1 GO:0000818 nuclear MIS12/MIND complex(GO:0000818)
0.3 2.4 GO:0070652 HAUS complex(GO:0070652)
0.2 1.7 GO:0030914 STAGA complex(GO:0030914)
0.2 0.7 GO:0031310 integral component of vacuolar membrane(GO:0031166) intrinsic component of vacuolar membrane(GO:0031310)
0.2 1.2 GO:0032133 chromosome passenger complex(GO:0032133)
0.2 1.1 GO:0031616 spindle pole centrosome(GO:0031616)
0.2 0.7 GO:0000931 gamma-tubulin large complex(GO:0000931) gamma-tubulin ring complex(GO:0008274)
0.2 1.4 GO:0005779 integral component of peroxisomal membrane(GO:0005779) intrinsic component of peroxisomal membrane(GO:0031231)
0.2 1.0 GO:0031258 lamellipodium membrane(GO:0031258)
0.2 0.3 GO:0000941 condensed nuclear chromosome inner kinetochore(GO:0000941)
0.1 1.1 GO:0043020 NADPH oxidase complex(GO:0043020)
0.1 0.6 GO:0005880 nuclear microtubule(GO:0005880)
0.1 0.6 GO:1904423 dehydrodolichyl diphosphate synthase complex(GO:1904423)
0.1 1.2 GO:0097550 transcriptional preinitiation complex(GO:0097550)
0.1 0.9 GO:0031261 DNA replication preinitiation complex(GO:0031261)
0.1 0.8 GO:0031428 box C/D snoRNP complex(GO:0031428)
0.1 1.1 GO:0032021 NELF complex(GO:0032021)
0.1 1.5 GO:0000815 ESCRT III complex(GO:0000815)
0.1 0.6 GO:0030870 Mre11 complex(GO:0030870)
0.1 0.8 GO:0033061 DNA recombinase mediator complex(GO:0033061)
0.1 0.4 GO:0019815 B cell receptor complex(GO:0019815)
0.1 0.9 GO:0032300 mismatch repair complex(GO:0032300)
0.1 0.6 GO:0098837 postsynaptic recycling endosome(GO:0098837)
0.1 0.7 GO:0031332 RISC complex(GO:0016442) RNAi effector complex(GO:0031332)
0.1 0.4 GO:0055087 Ski complex(GO:0055087)
0.1 1.2 GO:0017146 NMDA selective glutamate receptor complex(GO:0017146)
0.1 0.4 GO:0016593 Cdc73/Paf1 complex(GO:0016593)
0.1 0.5 GO:1902636 kinociliary basal body(GO:1902636)
0.1 0.6 GO:0061700 GATOR2 complex(GO:0061700)
0.1 0.4 GO:1990131 EGO complex(GO:0034448) Gtr1-Gtr2 GTPase complex(GO:1990131)
0.1 0.3 GO:0031673 H zone(GO:0031673)
0.1 0.4 GO:0008385 IkappaB kinase complex(GO:0008385)
0.1 1.3 GO:0043189 NuA4 histone acetyltransferase complex(GO:0035267) H4/H2A histone acetyltransferase complex(GO:0043189) H4 histone acetyltransferase complex(GO:1902562)
0.1 0.5 GO:0005826 actomyosin contractile ring(GO:0005826)
0.1 0.5 GO:0005952 cAMP-dependent protein kinase complex(GO:0005952)
0.1 0.9 GO:0044545 NSL complex(GO:0044545)
0.1 1.1 GO:1990907 beta-catenin-TCF complex(GO:1990907)
0.1 1.9 GO:0000421 autophagosome membrane(GO:0000421)
0.1 0.7 GO:0005666 DNA-directed RNA polymerase III complex(GO:0005666)
0.1 1.6 GO:0030686 90S preribosome(GO:0030686)
0.1 0.5 GO:0000974 Prp19 complex(GO:0000974)
0.1 1.0 GO:0044453 integral component of nuclear inner membrane(GO:0005639) intrinsic component of nuclear inner membrane(GO:0031229) nuclear membrane part(GO:0044453)
0.1 0.3 GO:0005879 axonemal microtubule(GO:0005879)
0.1 0.2 GO:0005968 Rab-protein geranylgeranyltransferase complex(GO:0005968)
0.0 1.1 GO:0030667 secretory granule membrane(GO:0030667)
0.0 1.3 GO:0033116 endoplasmic reticulum-Golgi intermediate compartment membrane(GO:0033116)
0.0 0.8 GO:0008278 cohesin complex(GO:0008278)
0.0 0.8 GO:0071339 MLL1/2 complex(GO:0044665) MLL1 complex(GO:0071339)
0.0 0.4 GO:0030122 AP-2 adaptor complex(GO:0030122)
0.0 2.4 GO:0016592 mediator complex(GO:0016592)
0.0 0.2 GO:0031313 extrinsic component of endosome membrane(GO:0031313)
0.0 2.2 GO:0005905 clathrin-coated pit(GO:0005905)
0.0 0.9 GO:0002116 semaphorin receptor complex(GO:0002116)
0.0 0.9 GO:0032039 integrator complex(GO:0032039)
0.0 0.4 GO:0036449 microtubule minus-end(GO:0036449)
0.0 0.5 GO:0016602 CCAAT-binding factor complex(GO:0016602)
0.0 0.6 GO:0034751 aryl hydrocarbon receptor complex(GO:0034751)
0.0 1.0 GO:0000795 synaptonemal complex(GO:0000795)
0.0 11.2 GO:0005730 nucleolus(GO:0005730)
0.0 0.7 GO:0045263 proton-transporting ATP synthase complex, coupling factor F(o)(GO:0045263)
0.0 1.0 GO:0030119 AP-type membrane coat adaptor complex(GO:0030119)
0.0 1.4 GO:0017053 transcriptional repressor complex(GO:0017053)
0.0 1.9 GO:0000118 histone deacetylase complex(GO:0000118)
0.0 0.5 GO:0035098 ESC/E(Z) complex(GO:0035098)
0.0 0.5 GO:0005847 mRNA cleavage and polyadenylation specificity factor complex(GO:0005847)
0.0 0.4 GO:0030904 retromer complex(GO:0030904)
0.0 0.7 GO:0030118 clathrin coat(GO:0030118) clathrin vesicle coat(GO:0030125)
0.0 0.5 GO:0031932 TORC2 complex(GO:0031932)
0.0 0.2 GO:0005665 DNA-directed RNA polymerase II, core complex(GO:0005665)
0.0 0.2 GO:1990130 Iml1 complex(GO:1990130)
0.0 0.2 GO:0071203 WASH complex(GO:0071203)
0.0 0.2 GO:0071007 U2-type catalytic step 2 spliceosome(GO:0071007)
0.0 0.2 GO:0035145 exon-exon junction complex(GO:0035145)
0.0 1.0 GO:0016514 SWI/SNF complex(GO:0016514)
0.0 0.2 GO:0072487 MSL complex(GO:0072487)
0.0 1.3 GO:0031941 filamentous actin(GO:0031941)
0.0 0.7 GO:0080008 Cul4-RING E3 ubiquitin ligase complex(GO:0080008)
0.0 0.7 GO:0071010 U2-type prespliceosome(GO:0071004) prespliceosome(GO:0071010)
0.0 1.9 GO:0000932 cytoplasmic mRNA processing body(GO:0000932)
0.0 0.2 GO:0071797 LUBAC complex(GO:0071797)
0.0 0.3 GO:0071014 post-mRNA release spliceosomal complex(GO:0071014)
0.0 0.5 GO:0071144 SMAD2-SMAD3 protein complex(GO:0071144)
0.0 3.8 GO:0016604 nuclear body(GO:0016604)
0.0 0.7 GO:0005680 anaphase-promoting complex(GO:0005680)
0.0 0.2 GO:0030140 trans-Golgi network transport vesicle(GO:0030140)
0.0 1.0 GO:0005876 spindle microtubule(GO:0005876)
0.0 1.8 GO:0031228 integral component of Golgi membrane(GO:0030173) intrinsic component of Golgi membrane(GO:0031228)
0.0 0.6 GO:0043596 nuclear replication fork(GO:0043596)
0.0 0.6 GO:0035861 site of double-strand break(GO:0035861)
0.0 2.7 GO:0016323 basolateral plasma membrane(GO:0016323)
0.0 0.6 GO:0005776 autophagosome(GO:0005776)
0.0 0.6 GO:0031463 Cul3-RING ubiquitin ligase complex(GO:0031463)
0.0 0.5 GO:0035102 PRC1 complex(GO:0035102)
0.0 0.5 GO:0016010 dystrophin-associated glycoprotein complex(GO:0016010) glycoprotein complex(GO:0090665)
0.0 0.9 GO:0044853 caveola(GO:0005901) plasma membrane raft(GO:0044853)
0.0 1.6 GO:0005814 centriole(GO:0005814)
0.0 2.2 GO:0000786 nucleosome(GO:0000786)
0.0 0.3 GO:0070187 telosome(GO:0070187)
0.0 1.3 GO:0005643 nuclear pore(GO:0005643)
0.0 2.2 GO:0005882 intermediate filament(GO:0005882)
0.0 1.3 GO:0031965 nuclear membrane(GO:0031965)
0.0 0.4 GO:0032420 stereocilium(GO:0032420)
0.0 1.0 GO:0032580 Golgi cisterna membrane(GO:0032580)
0.0 0.7 GO:0030134 ER to Golgi transport vesicle(GO:0030134)
0.0 0.3 GO:0045335 phagocytic vesicle(GO:0045335)
0.0 0.3 GO:0005669 transcription factor TFIID complex(GO:0005669)
0.0 0.1 GO:0043240 Fanconi anaemia nuclear complex(GO:0043240)
0.0 0.5 GO:0000777 condensed chromosome kinetochore(GO:0000777)
0.0 2.2 GO:0005813 centrosome(GO:0005813)
0.0 0.1 GO:0001772 immunological synapse(GO:0001772)
0.0 0.4 GO:0055029 nuclear DNA-directed RNA polymerase complex(GO:0055029)
0.0 0.8 GO:0019005 SCF ubiquitin ligase complex(GO:0019005)
0.0 0.2 GO:0098844 dendritic spine head(GO:0044327) postsynaptic endocytic zone membrane(GO:0098844)
0.0 0.1 GO:0001401 mitochondrial sorting and assembly machinery complex(GO:0001401)
0.0 0.0 GO:0044215 other organism(GO:0044215) other organism cell(GO:0044216) other organism part(GO:0044217) other organism cell membrane(GO:0044218) other organism membrane(GO:0044279)
0.0 1.0 GO:0005681 spliceosomal complex(GO:0005681)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 2.6 GO:0016715 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced ascorbate as one donor, and incorporation of one atom of oxygen(GO:0016715)
0.3 1.0 GO:0052717 tRNA-specific adenosine-34 deaminase activity(GO:0052717)
0.3 3.5 GO:0035198 miRNA binding(GO:0035198)
0.3 2.5 GO:0070137 ubiquitin-like protein-specific endopeptidase activity(GO:0070137) SUMO-specific endopeptidase activity(GO:0070139)
0.3 1.5 GO:0005542 folic acid binding(GO:0005542)
0.2 1.0 GO:0071253 connexin binding(GO:0071253)
0.2 0.7 GO:0008454 alpha-1,3-mannosylglycoprotein 4-beta-N-acetylglucosaminyltransferase activity(GO:0008454)
0.2 1.7 GO:0004128 cytochrome-b5 reductase activity, acting on NAD(P)H(GO:0004128)
0.2 0.6 GO:0004421 hydroxymethylglutaryl-CoA synthase activity(GO:0004421)
0.2 1.2 GO:1990247 N6-methyladenosine-containing RNA binding(GO:1990247)
0.2 0.6 GO:0002094 polyprenyltransferase activity(GO:0002094)
0.2 3.3 GO:0003688 DNA replication origin binding(GO:0003688)
0.2 0.7 GO:0003979 UDP-glucose 6-dehydrogenase activity(GO:0003979)
0.2 0.9 GO:0004565 beta-galactosidase activity(GO:0004565)
0.2 1.9 GO:0016594 glycine binding(GO:0016594)
0.2 2.7 GO:0046975 histone methyltransferase activity (H3-K36 specific)(GO:0046975)
0.2 1.3 GO:0072518 Rho-dependent protein serine/threonine kinase activity(GO:0072518)
0.2 0.8 GO:0008486 endopolyphosphatase activity(GO:0000298) diphosphoinositol-polyphosphate diphosphatase activity(GO:0008486) bis(5'-adenosyl)-hexaphosphatase activity(GO:0034431) bis(5'-adenosyl)-pentaphosphatase activity(GO:0034432)
0.2 0.6 GO:0031151 histone methyltransferase activity (H3-K79 specific)(GO:0031151)
0.2 1.4 GO:0004176 ATP-dependent peptidase activity(GO:0004176)
0.2 0.6 GO:0015018 galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase activity(GO:0015018)
0.1 0.7 GO:0030169 low-density lipoprotein particle binding(GO:0030169)
0.1 0.6 GO:0034511 U3 snoRNA binding(GO:0034511)
0.1 1.6 GO:0043325 phosphatidylinositol-3,4-bisphosphate binding(GO:0043325)
0.1 0.8 GO:0017150 tRNA dihydrouridine synthase activity(GO:0017150)
0.1 1.4 GO:0043142 single-stranded DNA-dependent ATP-dependent DNA helicase activity(GO:0017116) single-stranded DNA-dependent ATPase activity(GO:0043142)
0.1 2.4 GO:0019789 SUMO transferase activity(GO:0019789)
0.1 0.7 GO:0015616 DNA translocase activity(GO:0015616)
0.1 0.6 GO:0008311 double-stranded DNA exodeoxyribonuclease activity(GO:0008309) double-stranded DNA 3'-5' exodeoxyribonuclease activity(GO:0008311)
0.1 1.9 GO:0043015 gamma-tubulin binding(GO:0043015)
0.1 0.7 GO:0001047 core promoter sequence-specific DNA binding(GO:0001046) core promoter binding(GO:0001047)
0.1 0.7 GO:0016793 dGTPase activity(GO:0008832) triphosphoric monoester hydrolase activity(GO:0016793)
0.1 2.4 GO:0005452 inorganic anion exchanger activity(GO:0005452)
0.1 1.3 GO:0005220 inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity(GO:0005220)
0.1 1.4 GO:0005432 calcium:sodium antiporter activity(GO:0005432)
0.1 3.3 GO:0005227 calcium activated cation channel activity(GO:0005227)
0.1 0.6 GO:0000014 single-stranded DNA endodeoxyribonuclease activity(GO:0000014)
0.1 0.3 GO:0050135 NAD(P)+ nucleosidase activity(GO:0050135)
0.1 0.5 GO:0008545 JUN kinase kinase activity(GO:0008545)
0.1 0.9 GO:0004586 ornithine decarboxylase activity(GO:0004586)
0.1 2.0 GO:0015095 magnesium ion transmembrane transporter activity(GO:0015095)
0.1 1.4 GO:0070739 protein-glutamic acid ligase activity(GO:0070739) tubulin-glutamic acid ligase activity(GO:0070740)
0.1 1.0 GO:0005042 netrin receptor activity(GO:0005042)
0.1 2.1 GO:0003887 DNA-directed DNA polymerase activity(GO:0003887)
0.1 0.6 GO:0070016 armadillo repeat domain binding(GO:0070016)
0.1 0.3 GO:0016165 linoleate 13S-lipoxygenase activity(GO:0016165)
0.1 4.3 GO:0000049 tRNA binding(GO:0000049)
0.1 0.7 GO:0015181 arginine transmembrane transporter activity(GO:0015181)
0.1 0.4 GO:0015432 canalicular bile acid transmembrane transporter activity(GO:0015126) bile acid-exporting ATPase activity(GO:0015432)
0.1 1.6 GO:0034237 protein kinase A regulatory subunit binding(GO:0034237)
0.1 0.7 GO:0008476 protein-tyrosine sulfotransferase activity(GO:0008476)
0.1 0.9 GO:0047676 arachidonate-CoA ligase activity(GO:0047676)
0.1 0.6 GO:0070728 leucine binding(GO:0070728)
0.1 0.2 GO:0030623 U5 snRNA binding(GO:0030623)
0.1 0.9 GO:0046933 proton-transporting ATP synthase activity, rotational mechanism(GO:0046933)
0.1 1.4 GO:0045159 myosin II binding(GO:0045159)
0.1 0.5 GO:0004022 alcohol dehydrogenase (NAD) activity(GO:0004022)
0.1 0.7 GO:0016176 superoxide-generating NADPH oxidase activator activity(GO:0016176)
0.1 0.2 GO:0043739 G/U mismatch-specific uracil-DNA glycosylase activity(GO:0043739)
0.1 0.5 GO:0008603 cAMP-dependent protein kinase regulator activity(GO:0008603)
0.1 1.0 GO:0016884 carbon-nitrogen ligase activity, with glutamine as amido-N-donor(GO:0016884)
0.1 0.3 GO:0004605 phosphatidate cytidylyltransferase activity(GO:0004605)
0.1 0.5 GO:0000992 polymerase III regulatory region sequence-specific DNA binding(GO:0000992) RNA polymerase III type 3 promoter sequence-specific DNA binding(GO:0001006) RNA polymerase III regulatory region DNA binding(GO:0001016) RNA polymerase III type 3 promoter DNA binding(GO:0001032)
0.1 0.3 GO:0004558 alpha-1,4-glucosidase activity(GO:0004558)
0.1 0.7 GO:0004568 chitinase activity(GO:0004568)
0.1 0.9 GO:0035250 UDP-galactosyltransferase activity(GO:0035250)
0.1 0.2 GO:0036310 annealing helicase activity(GO:0036310)
0.1 0.6 GO:0004865 protein serine/threonine phosphatase inhibitor activity(GO:0004865)
0.1 0.6 GO:0015924 mannosyl-oligosaccharide 1,2-alpha-mannosidase activity(GO:0004571) mannosyl-oligosaccharide mannosidase activity(GO:0015924)
0.1 1.2 GO:0004972 NMDA glutamate receptor activity(GO:0004972)
0.1 4.7 GO:0003724 RNA helicase activity(GO:0003724)
0.1 0.7 GO:0035612 AP-2 adaptor complex binding(GO:0035612)
0.1 1.0 GO:0030983 mismatched DNA binding(GO:0030983)
0.1 2.6 GO:0008373 sialyltransferase activity(GO:0008373)
0.1 0.6 GO:0003726 double-stranded RNA adenosine deaminase activity(GO:0003726) tRNA-specific adenosine deaminase activity(GO:0008251)
0.1 0.7 GO:0005231 extracellular ATP-gated cation channel activity(GO:0004931) excitatory extracellular ligand-gated ion channel activity(GO:0005231) ATP-gated ion channel activity(GO:0035381)
0.1 0.4 GO:0016863 intramolecular oxidoreductase activity, transposing C=C bonds(GO:0016863)
0.1 0.2 GO:0034416 bisphosphoglycerate phosphatase activity(GO:0034416)
0.1 1.0 GO:0008239 dipeptidyl-peptidase activity(GO:0008239)
0.1 1.2 GO:1990841 promoter-specific chromatin binding(GO:1990841)
0.1 0.7 GO:0003756 protein disulfide isomerase activity(GO:0003756) intramolecular oxidoreductase activity, transposing S-S bonds(GO:0016864)
0.1 0.3 GO:0004001 adenosine kinase activity(GO:0004001)
0.1 1.8 GO:0030374 ligand-dependent nuclear receptor transcription coactivator activity(GO:0030374)
0.1 0.2 GO:0004663 Rab geranylgeranyltransferase activity(GO:0004663)
0.1 0.4 GO:0045735 nutrient reservoir activity(GO:0045735)
0.0 0.5 GO:0005049 nuclear export signal receptor activity(GO:0005049)
0.0 0.8 GO:0008649 rRNA methyltransferase activity(GO:0008649)
0.0 0.2 GO:0035575 histone demethylase activity (H4-K20 specific)(GO:0035575)
0.0 0.2 GO:0008169 C-methyltransferase activity(GO:0008169)
0.0 0.7 GO:0061578 Lys63-specific deubiquitinase activity(GO:0061578)
0.0 1.5 GO:0035064 methylated histone binding(GO:0035064)
0.0 0.3 GO:0004839 ubiquitin activating enzyme activity(GO:0004839)
0.0 0.6 GO:0005537 mannose binding(GO:0005537)
0.0 0.5 GO:0032454 histone demethylase activity (H3-K9 specific)(GO:0032454)
0.0 0.9 GO:0016888 endodeoxyribonuclease activity, producing 5'-phosphomonoesters(GO:0016888)
0.0 0.7 GO:0061608 nucleocytoplasmic transporter activity(GO:0005487) nuclear import signal receptor activity(GO:0061608)
0.0 0.3 GO:0004743 pyruvate kinase activity(GO:0004743)
0.0 0.5 GO:0047498 calcium-dependent phospholipase A2 activity(GO:0047498)
0.0 1.1 GO:0001103 RNA polymerase II repressing transcription factor binding(GO:0001103)
0.0 0.3 GO:0098809 nitrite reductase activity(GO:0098809)
0.0 0.3 GO:0004748 ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor(GO:0004748) oxidoreductase activity, acting on CH or CH2 groups, disulfide as acceptor(GO:0016728) ribonucleoside-diphosphate reductase activity(GO:0061731)
0.0 0.8 GO:0000993 RNA polymerase II core binding(GO:0000993)
0.0 0.5 GO:0004656 procollagen-proline 4-dioxygenase activity(GO:0004656)
0.0 0.3 GO:0098505 G-rich strand telomeric DNA binding(GO:0098505)
0.0 0.2 GO:0004392 heme oxygenase (decyclizing) activity(GO:0004392)
0.0 0.3 GO:0050262 ribosylnicotinamide kinase activity(GO:0050262)
0.0 0.8 GO:0015279 store-operated calcium channel activity(GO:0015279)
0.0 0.3 GO:0016721 superoxide dismutase activity(GO:0004784) oxidoreductase activity, acting on superoxide radicals as acceptor(GO:0016721)
0.0 0.3 GO:0051920 peroxiredoxin activity(GO:0051920)
0.0 0.9 GO:0003899 DNA-directed RNA polymerase activity(GO:0003899) RNA polymerase activity(GO:0034062)
0.0 0.2 GO:0008140 cAMP response element binding protein binding(GO:0008140)
0.0 0.4 GO:0008568 microtubule-severing ATPase activity(GO:0008568)
0.0 1.6 GO:0003746 translation elongation factor activity(GO:0003746)
0.0 0.1 GO:0003999 adenine phosphoribosyltransferase activity(GO:0003999)
0.0 0.4 GO:0043028 cysteine-type endopeptidase inhibitor activity involved in apoptotic process(GO:0043027) cysteine-type endopeptidase regulator activity involved in apoptotic process(GO:0043028)
0.0 0.2 GO:0016312 inositol bisphosphate phosphatase activity(GO:0016312)
0.0 0.5 GO:0048018 receptor activator activity(GO:0030546) receptor agonist activity(GO:0048018)
0.0 0.2 GO:0003983 UTP:glucose-1-phosphate uridylyltransferase activity(GO:0003983) UTP-monosaccharide-1-phosphate uridylyltransferase activity(GO:0051748)
0.0 0.1 GO:0008510 sodium:bicarbonate symporter activity(GO:0008510)
0.0 0.3 GO:0016909 JUN kinase activity(GO:0004705) SAP kinase activity(GO:0016909)
0.0 0.2 GO:0004619 bisphosphoglycerate mutase activity(GO:0004082) phosphoglycerate mutase activity(GO:0004619)
0.0 0.8 GO:0008175 tRNA methyltransferase activity(GO:0008175)
0.0 0.4 GO:0030507 spectrin binding(GO:0030507)
0.0 0.5 GO:0051018 protein kinase A binding(GO:0051018)
0.0 0.1 GO:0016453 C-acetyltransferase activity(GO:0016453)
0.0 0.3 GO:0016840 carbon-nitrogen lyase activity(GO:0016840)
0.0 0.5 GO:0008242 omega peptidase activity(GO:0008242)
0.0 0.3 GO:0015232 heme transporter activity(GO:0015232)
0.0 0.5 GO:0008173 RNA methyltransferase activity(GO:0008173)
0.0 0.1 GO:0004969 histamine receptor activity(GO:0004969)
0.0 0.2 GO:0034714 type III transforming growth factor beta receptor binding(GO:0034714)
0.0 6.4 GO:0046982 protein heterodimerization activity(GO:0046982)
0.0 0.3 GO:0004731 purine-nucleoside phosphorylase activity(GO:0004731)
0.0 0.3 GO:0035259 glucocorticoid receptor binding(GO:0035259)
0.0 0.5 GO:0033691 sialic acid binding(GO:0033691)
0.0 0.4 GO:0043495 protein anchor(GO:0043495)
0.0 0.6 GO:0043548 phosphatidylinositol 3-kinase binding(GO:0043548)
0.0 0.9 GO:0017154 semaphorin receptor activity(GO:0017154)
0.0 0.1 GO:0032183 SUMO binding(GO:0032183)
0.0 0.4 GO:0035615 clathrin adaptor activity(GO:0035615) endocytic adaptor activity(GO:0098748)
0.0 1.1 GO:0043022 ribosome binding(GO:0043022)
0.0 0.4 GO:0070530 K63-linked polyubiquitin binding(GO:0070530)
0.0 0.3 GO:0004028 3-chloroallyl aldehyde dehydrogenase activity(GO:0004028)
0.0 0.4 GO:0004767 sphingomyelin phosphodiesterase activity(GO:0004767)
0.0 0.8 GO:0017056 structural constituent of nuclear pore(GO:0017056)
0.0 0.2 GO:0017091 AU-rich element binding(GO:0017091) mRNA 3'-UTR AU-rich region binding(GO:0035925)
0.0 0.4 GO:0000828 inositol hexakisphosphate kinase activity(GO:0000828)
0.0 0.5 GO:0070411 I-SMAD binding(GO:0070411)
0.0 0.2 GO:0016634 oxidoreductase activity, acting on the CH-CH group of donors, oxygen as acceptor(GO:0016634)
0.0 0.3 GO:0004465 lipoprotein lipase activity(GO:0004465)
0.0 3.6 GO:0004222 metalloendopeptidase activity(GO:0004222)
0.0 0.3 GO:0016251 obsolete general RNA polymerase II transcription factor activity(GO:0016251)
0.0 1.9 GO:0004386 helicase activity(GO:0004386)
0.0 1.2 GO:0030898 actin-dependent ATPase activity(GO:0030898)
0.0 0.4 GO:0004622 lysophospholipase activity(GO:0004622)
0.0 0.7 GO:0015459 potassium channel regulator activity(GO:0015459)
0.0 0.2 GO:0030368 interleukin-17 receptor activity(GO:0030368)
0.0 0.1 GO:0008502 melatonin receptor activity(GO:0008502)
0.0 0.1 GO:0004517 nitric-oxide synthase activity(GO:0004517)
0.0 0.2 GO:0004526 ribonuclease P activity(GO:0004526)
0.0 3.4 GO:0042802 identical protein binding(GO:0042802)
0.0 0.9 GO:0001786 phosphatidylserine binding(GO:0001786)
0.0 2.2 GO:0036459 thiol-dependent ubiquitin-specific protease activity(GO:0004843) thiol-dependent ubiquitinyl hydrolase activity(GO:0036459) ubiquitinyl hydrolase activity(GO:0101005)
0.0 0.1 GO:0019865 IgE binding(GO:0019863) immunoglobulin binding(GO:0019865)
0.0 0.8 GO:0019903 protein phosphatase binding(GO:0019903)
0.0 1.1 GO:0030215 semaphorin receptor binding(GO:0030215)
0.0 1.0 GO:0019209 kinase activator activity(GO:0019209) protein kinase activator activity(GO:0030295)
0.0 5.8 GO:0005085 guanyl-nucleotide exchange factor activity(GO:0005085)
0.0 0.7 GO:0008013 beta-catenin binding(GO:0008013)
0.0 3.4 GO:0019901 protein kinase binding(GO:0019901)
0.0 0.1 GO:0070330 aromatase activity(GO:0070330)
0.0 0.1 GO:0030504 inorganic diphosphate transmembrane transporter activity(GO:0030504)
0.0 0.3 GO:0098599 palmitoyl-(protein) hydrolase activity(GO:0008474) palmitoyl hydrolase activity(GO:0098599)
0.0 0.4 GO:0001540 beta-amyloid binding(GO:0001540)
0.0 0.3 GO:0035257 nuclear hormone receptor binding(GO:0035257)
0.0 0.9 GO:0016278 lysine N-methyltransferase activity(GO:0016278) protein-lysine N-methyltransferase activity(GO:0016279)
0.0 0.5 GO:0004435 phosphatidylinositol phospholipase C activity(GO:0004435) phospholipase C activity(GO:0004629)
0.0 0.5 GO:0000175 3'-5'-exoribonuclease activity(GO:0000175)
0.0 0.4 GO:0017080 sodium channel regulator activity(GO:0017080)
0.0 1.1 GO:0008375 acetylglucosaminyltransferase activity(GO:0008375)
0.0 0.3 GO:0030159 receptor signaling complex scaffold activity(GO:0030159)
0.0 0.6 GO:0005251 delayed rectifier potassium channel activity(GO:0005251)
0.0 0.4 GO:0031683 G-protein beta/gamma-subunit complex binding(GO:0031683)
0.0 0.2 GO:0070915 lysophosphatidic acid receptor activity(GO:0070915)
0.0 0.4 GO:0008198 ferrous iron binding(GO:0008198)
0.0 6.9 GO:0004842 ubiquitin-protein transferase activity(GO:0004842)
0.0 0.3 GO:0016628 oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor(GO:0016628)
0.0 0.1 GO:0008097 5S rRNA binding(GO:0008097)
0.0 2.5 GO:0030246 carbohydrate binding(GO:0030246)
0.0 0.2 GO:0035497 cAMP response element binding(GO:0035497)
0.0 0.5 GO:0003707 steroid hormone receptor activity(GO:0003707)
0.0 0.5 GO:0004540 ribonuclease activity(GO:0004540)
0.0 0.5 GO:0031625 ubiquitin protein ligase binding(GO:0031625)
0.0 0.1 GO:0030628 pre-mRNA 3'-splice site binding(GO:0030628)
0.0 0.4 GO:0019003 GDP binding(GO:0019003)
0.0 0.0 GO:0001875 lipopolysaccharide receptor activity(GO:0001875)
0.0 0.1 GO:0004445 inositol-polyphosphate 5-phosphatase activity(GO:0004445)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 2.0 PID P38 GAMMA DELTA PATHWAY Signaling mediated by p38-gamma and p38-delta
0.1 1.6 ST G ALPHA S PATHWAY G alpha s Pathway
0.1 2.5 PID AURORA A PATHWAY Aurora A signaling
0.1 1.8 PID DNA PK PATHWAY DNA-PK pathway in nonhomologous end joining
0.1 2.5 PID IL12 2PATHWAY IL12-mediated signaling events
0.1 1.7 PID MYC PATHWAY C-MYC pathway
0.1 0.4 PID IL12 STAT4 PATHWAY IL12 signaling mediated by STAT4
0.0 1.6 PID FOXO PATHWAY FoxO family signaling
0.0 1.1 PID BARD1 PATHWAY BARD1 signaling events
0.0 0.6 PID ER NONGENOMIC PATHWAY Plasma membrane estrogen receptor signaling
0.0 1.0 PID ERBB2 ERBB3 PATHWAY ErbB2/ErbB3 signaling events
0.0 0.8 PID ARF6 PATHWAY Arf6 signaling events
0.0 0.9 PID P38 ALPHA BETA DOWNSTREAM PATHWAY Signaling mediated by p38-alpha and p38-beta
0.0 0.4 PID LPA4 PATHWAY LPA4-mediated signaling events
0.0 0.5 PID INTEGRIN A4B1 PATHWAY Alpha4 beta1 integrin signaling events
0.0 0.4 PID TOLL ENDOGENOUS PATHWAY Endogenous TLR signaling
0.0 1.1 PID MYC ACTIV PATHWAY Validated targets of C-MYC transcriptional activation
0.0 0.7 PID RET PATHWAY Signaling events regulated by Ret tyrosine kinase
0.0 0.7 PID FRA PATHWAY Validated transcriptional targets of AP1 family members Fra1 and Fra2
0.0 0.7 SIG PIP3 SIGNALING IN CARDIAC MYOCTES Genes related to PIP3 signaling in cardiac myocytes
0.0 0.4 PID TCPTP PATHWAY Signaling events mediated by TCPTP
0.0 0.4 PID INSULIN GLUCOSE PATHWAY Insulin-mediated glucose transport
0.0 0.5 PID RXR VDR PATHWAY RXR and RAR heterodimerization with other nuclear receptor
0.0 0.4 PID PRL SIGNALING EVENTS PATHWAY Signaling events mediated by PRL
0.0 0.4 SA CASPASE CASCADE Apoptosis is mediated by caspases, cysteine proteases arranged in a proteolytic cascade.
0.0 0.6 PID AR TF PATHWAY Regulation of Androgen receptor activity
0.0 0.7 PID CXCR4 PATHWAY CXCR4-mediated signaling events
0.0 0.4 PID KIT PATHWAY Signaling events mediated by Stem cell factor receptor (c-Kit)
0.0 0.5 PID AJDISS 2PATHWAY Posttranslational regulation of adherens junction stability and dissassembly
0.0 0.3 PID FOXM1 PATHWAY FOXM1 transcription factor network
0.0 0.4 PID MTOR 4PATHWAY mTOR signaling pathway
0.0 0.9 PID HDAC CLASSI PATHWAY Signaling events mediated by HDAC Class I
0.0 0.2 PID FAS PATHWAY FAS (CD95) signaling pathway
0.0 0.2 PID ECADHERIN NASCENT AJ PATHWAY E-cadherin signaling in the nascent adherens junction
0.0 0.8 PID BETA CATENIN NUC PATHWAY Regulation of nuclear beta catenin signaling and target gene transcription
0.0 0.1 PID INTEGRIN4 PATHWAY Alpha6 beta4 integrin-ligand interactions
0.0 0.4 PID ERA GENOMIC PATHWAY Validated nuclear estrogen receptor alpha network
0.0 0.4 PID PLK1 PATHWAY PLK1 signaling events

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.3 REACTOME RECRUITMENT OF NUMA TO MITOTIC CENTROSOMES Genes involved in Recruitment of NuMA to mitotic centrosomes
0.1 1.6 REACTOME METABOLISM OF POLYAMINES Genes involved in Metabolism of polyamines
0.1 2.1 REACTOME A TETRASACCHARIDE LINKER SEQUENCE IS REQUIRED FOR GAG SYNTHESIS Genes involved in A tetrasaccharide linker sequence is required for GAG synthesis
0.1 3.9 REACTOME ACTIVATION OF THE PRE REPLICATIVE COMPLEX Genes involved in Activation of the pre-replicative complex
0.1 1.0 REACTOME ACTIVATION OF BH3 ONLY PROTEINS Genes involved in Activation of BH3-only proteins
0.1 0.9 REACTOME TERMINATION OF O GLYCAN BIOSYNTHESIS Genes involved in Termination of O-glycan biosynthesis
0.1 0.5 REACTOME INTEGRATION OF PROVIRUS Genes involved in Integration of provirus
0.1 1.0 REACTOME SYNTHESIS SECRETION AND INACTIVATION OF GLP1 Genes involved in Synthesis, Secretion, and Inactivation of Glucagon-like Peptide-1 (GLP-1)
0.1 1.7 REACTOME RIP MEDIATED NFKB ACTIVATION VIA DAI Genes involved in RIP-mediated NFkB activation via DAI
0.1 1.5 REACTOME IRON UPTAKE AND TRANSPORT Genes involved in Iron uptake and transport
0.1 1.1 REACTOME SYNTHESIS OF PE Genes involved in Synthesis of PE
0.1 1.1 REACTOME ENOS ACTIVATION AND REGULATION Genes involved in eNOS activation and regulation
0.1 0.7 REACTOME HYALURONAN UPTAKE AND DEGRADATION Genes involved in Hyaluronan uptake and degradation
0.1 0.5 REACTOME CD28 DEPENDENT VAV1 PATHWAY Genes involved in CD28 dependent Vav1 pathway
0.1 0.6 REACTOME SLBP DEPENDENT PROCESSING OF REPLICATION DEPENDENT HISTONE PRE MRNAS Genes involved in SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs
0.1 0.8 REACTOME PKA MEDIATED PHOSPHORYLATION OF CREB Genes involved in PKA-mediated phosphorylation of CREB
0.1 0.8 REACTOME PURINE RIBONUCLEOSIDE MONOPHOSPHATE BIOSYNTHESIS Genes involved in Purine ribonucleoside monophosphate biosynthesis
0.0 1.2 REACTOME RNA POL III TRANSCRIPTION INITIATION FROM TYPE 3 PROMOTER Genes involved in RNA Polymerase III Transcription Initiation From Type 3 Promoter
0.0 1.4 REACTOME ENDOSOMAL SORTING COMPLEX REQUIRED FOR TRANSPORT ESCRT Genes involved in Endosomal Sorting Complex Required For Transport (ESCRT)
0.0 0.8 REACTOME MRNA DECAY BY 5 TO 3 EXORIBONUCLEASE Genes involved in mRNA Decay by 5' to 3' Exoribonuclease
0.0 0.8 REACTOME HOMOLOGOUS RECOMBINATION REPAIR OF REPLICATION INDEPENDENT DOUBLE STRAND BREAKS Genes involved in Homologous recombination repair of replication-independent double-strand breaks
0.0 0.7 REACTOME IMMUNOREGULATORY INTERACTIONS BETWEEN A LYMPHOID AND A NON LYMPHOID CELL Genes involved in Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
0.0 0.4 REACTOME RETROGRADE NEUROTROPHIN SIGNALLING Genes involved in Retrograde neurotrophin signalling
0.0 0.2 REACTOME PLATELET AGGREGATION PLUG FORMATION Genes involved in Platelet Aggregation (Plug Formation)
0.0 2.3 REACTOME METABOLISM OF VITAMINS AND COFACTORS Genes involved in Metabolism of vitamins and cofactors
0.0 1.0 REACTOME CHOLESTEROL BIOSYNTHESIS Genes involved in Cholesterol biosynthesis
0.0 0.4 REACTOME INTRINSIC PATHWAY FOR APOPTOSIS Genes involved in Intrinsic Pathway for Apoptosis
0.0 0.8 REACTOME PHOSPHORYLATION OF THE APC C Genes involved in Phosphorylation of the APC/C
0.0 0.3 REACTOME GENERATION OF SECOND MESSENGER MOLECULES Genes involved in Generation of second messenger molecules
0.0 1.9 REACTOME MITOTIC PROMETAPHASE Genes involved in Mitotic Prometaphase
0.0 0.2 REACTOME ACTIVATION OF CHAPERONE GENES BY ATF6 ALPHA Genes involved in Activation of Chaperone Genes by ATF6-alpha
0.0 1.1 REACTOME ACTIVATION OF CHAPERONE GENES BY XBP1S Genes involved in Activation of Chaperone Genes by XBP1(S)
0.0 1.0 REACTOME NRAGE SIGNALS DEATH THROUGH JNK Genes involved in NRAGE signals death through JNK
0.0 0.4 REACTOME REGULATORY RNA PATHWAYS Genes involved in Regulatory RNA pathways
0.0 0.7 REACTOME RNA POL II TRANSCRIPTION PRE INITIATION AND PROMOTER OPENING Genes involved in RNA Polymerase II Transcription Pre-Initiation And Promoter Opening
0.0 0.1 REACTOME SYNTHESIS SECRETION AND DEACYLATION OF GHRELIN Genes involved in Synthesis, Secretion, and Deacylation of Ghrelin
0.0 0.6 REACTOME GLYCOSPHINGOLIPID METABOLISM Genes involved in Glycosphingolipid metabolism
0.0 0.2 REACTOME SRP DEPENDENT COTRANSLATIONAL PROTEIN TARGETING TO MEMBRANE Genes involved in SRP-dependent cotranslational protein targeting to membrane
0.0 0.3 REACTOME DOWNREGULATION OF SMAD2 3 SMAD4 TRANSCRIPTIONAL ACTIVITY Genes involved in Downregulation of SMAD2/3:SMAD4 transcriptional activity
0.0 0.1 REACTOME HS GAG DEGRADATION Genes involved in HS-GAG degradation
0.0 0.2 REACTOME ROLE OF DCC IN REGULATING APOPTOSIS Genes involved in Role of DCC in regulating apoptosis
0.0 0.8 REACTOME GOLGI ASSOCIATED VESICLE BIOGENESIS Genes involved in Golgi Associated Vesicle Biogenesis
0.0 0.4 REACTOME PIP3 ACTIVATES AKT SIGNALING Genes involved in PIP3 activates AKT signaling
0.0 1.3 REACTOME PPARA ACTIVATES GENE EXPRESSION Genes involved in PPARA Activates Gene Expression
0.0 0.3 REACTOME PLATELET CALCIUM HOMEOSTASIS Genes involved in Platelet calcium homeostasis
0.0 0.2 REACTOME TGF BETA RECEPTOR SIGNALING ACTIVATES SMADS Genes involved in TGF-beta receptor signaling activates SMADs
0.0 0.7 REACTOME MITOCHONDRIAL PROTEIN IMPORT Genes involved in Mitochondrial Protein Import
0.0 0.3 REACTOME SYNTHESIS AND INTERCONVERSION OF NUCLEOTIDE DI AND TRIPHOSPHATES Genes involved in Synthesis and interconversion of nucleotide di- and triphosphates
0.0 0.1 REACTOME BASE FREE SUGAR PHOSPHATE REMOVAL VIA THE SINGLE NUCLEOTIDE REPLACEMENT PATHWAY Genes involved in Base-free sugar-phosphate removal via the single-nucleotide replacement pathway
0.0 0.2 REACTOME IONOTROPIC ACTIVITY OF KAINATE RECEPTORS Genes involved in Ionotropic activity of Kainate Receptors
0.0 0.8 REACTOME FACTORS INVOLVED IN MEGAKARYOCYTE DEVELOPMENT AND PLATELET PRODUCTION Genes involved in Factors involved in megakaryocyte development and platelet production
0.0 0.1 REACTOME PURINE SALVAGE Genes involved in Purine salvage