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PRJNA195909:zebrafish embryo and larva development

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Results for irx2a

Z-value: 0.43

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Transcription factors associated with irx2a

Gene Symbol Gene ID Gene Info
ENSDARG00000001785 iroquois homeobox 2a

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
irx2adr11_v1_chr16_-_560574_5605740.551.3e-01Click!

Activity profile of irx2a motif

Sorted Z-values of irx2a motif

Promoter Log-likelihood Transcript Gene Gene Info
chr23_+_32499916 0.81 ENSDART00000134811
si:dkey-261h17.1
chr7_-_2039060 0.72 ENSDART00000173879
si:cabz01007794.1
chr11_+_3254252 0.63 ENSDART00000123568
premelanosome protein a
chr3_-_61203203 0.61 ENSDART00000171787
parvalbumin 1
chr9_+_31282161 0.61 ENSDART00000010774
zic family member 2 (odd-paired homolog, Drosophila), a
chr12_+_36891483 0.61 ENSDART00000048927
COX10 heme A:farnesyltransferase cytochrome c oxidase assembly factor
chr1_-_44940830 0.60 ENSDART00000097500
ENSDART00000134464
ENSDART00000137216
transmembrane protein 176
chr20_+_2281933 0.59 ENSDART00000137579
si:ch73-18b11.2
chr19_-_41069573 0.54 ENSDART00000111982
ENSDART00000193142
sarcoglycan, epsilon
chr6_-_18698006 0.53 ENSDART00000170128
rhomboid, veinlet-like 3 (Drosophila)
chr7_-_27033080 0.52 ENSDART00000173516
nucleobindin 2a
chr19_+_18739085 0.52 ENSDART00000188868
sperm acrosome associated 4 like
chr14_-_48103207 0.50 ENSDART00000056712
electron-transferring-flavoprotein dehydrogenase
chr24_-_12938922 0.49 ENSDART00000024084
phosphoenolpyruvate carboxykinase 2 (mitochondrial)
chr19_+_8973042 0.46 ENSDART00000039597
cellular retinoic acid binding protein 2, b
chr7_-_73725701 0.44 ENSDART00000158525
calsequestrin 1b
chr21_+_723998 0.44 ENSDART00000160956
ornithine decarboxylase antizyme 1b
chr8_+_44926946 0.43 ENSDART00000098567
zgc:154046
chr23_+_36653376 0.42 ENSDART00000053189
G protein-coupled receptor 182
chr24_-_26304386 0.42 ENSDART00000175416
otospiralin
chr19_+_30388186 0.41 ENSDART00000103474
tetraspanin 13b
chr19_+_30387999 0.41 ENSDART00000145396
tetraspanin 13b
chr23_+_42819221 0.40 ENSDART00000180495
myosin, light chain 9a, regulatory
chr24_-_37955993 0.40 ENSDART00000041805
meteorin, glial cell differentiation regulator
chr2_+_22795494 0.40 ENSDART00000042255
RAB6B, member RAS oncogene family b
chr8_+_23213320 0.39 ENSDART00000032996
ENSDART00000137536
pancreatic progenitor cell differentiation and proliferation factor a
chr1_+_44941031 0.37 ENSDART00000141145
si:dkey-9i23.16
chr8_+_26565512 0.36 ENSDART00000140980
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3bl
chr14_-_25985698 0.35 ENSDART00000172909
ENSDART00000123053
antioxidant 1 copper chaperone
chr4_-_12725513 0.35 ENSDART00000132286
microsomal glutathione S-transferase 1.2
chr6_-_18698456 0.35 ENSDART00000166587
rhomboid, veinlet-like 3 (Drosophila)
chr22_-_21314821 0.34 ENSDART00000105546
ENSDART00000135388
CDC28 protein kinase regulatory subunit 2
chr3_+_32689707 0.34 ENSDART00000029262
si:dkey-16l2.17
chr8_-_25011157 0.33 ENSDART00000078795
adenosylhomocysteinase-like 1
chr24_-_7632187 0.32 ENSDART00000041714
ATPase H+ transporting V0 subunit a1b
chr7_-_23873173 0.32 ENSDART00000101408
zgc:162171
chr9_-_56231387 0.32 ENSDART00000149851
ribosomal protein L31
chr11_+_44579865 0.31 ENSDART00000173425
nidogen 1b
chr6_-_7720332 0.31 ENSDART00000135945
ribosomal protein SA
chr6_-_19340889 0.31 ENSDART00000181407
MIF4G domain containing a
chr6_-_19341184 0.31 ENSDART00000168236
ENSDART00000167674
MIF4G domain containing a
chr21_-_37733287 0.30 ENSDART00000157826
membrane protein, palmitoylated 1
chr2_+_47581997 0.29 ENSDART00000112579
secretogranin II (chromogranin C), b
chr17_-_35881841 0.29 ENSDART00000110040
SRY (sex determining region Y)-box 11a
chr2_-_10014821 0.29 ENSDART00000185525

chr5_+_37785152 0.29 ENSDART00000053511
ENSDART00000189812
myosin Ic, paralog a
chr23_-_39849155 0.29 ENSDART00000115330
protein phosphatase 1, regulatory (inhibitor) subunit 14C
chr6_-_18698669 0.28 ENSDART00000168554
ENSDART00000175205
rhomboid, veinlet-like 3 (Drosophila)
chr10_-_17083180 0.28 ENSDART00000170083
family with sequence similarity 166, member B
chr14_+_32022272 0.28 ENSDART00000105760
zic family member 6
chr17_+_32571584 0.28 ENSDART00000087565
eva-1 homolog A (C. elegans)
chr11_-_21585176 0.28 ENSDART00000045391
SLIT-ROBO Rho GTPase activating protein 2
chr8_-_27858458 0.27 ENSDART00000132632
ENSDART00000136562
CTTNBP2 N-terminal like b
chr13_+_18533005 0.27 ENSDART00000136024
finTRIM family, member 14-like
chr20_+_26349002 0.27 ENSDART00000152842
spectrin repeat containing, nuclear envelope 1a
chr21_-_9991502 0.27 ENSDART00000169320
endothelial cell-specific molecule 1
chr8_-_30791266 0.27 ENSDART00000062220
glutathione S-transferase theta 1a
chr23_+_23658474 0.27 ENSDART00000162838
agrin
chr21_+_5915041 0.27 ENSDART00000151370
proline dehydrogenase (oxidase) 1a
chr3_+_62161184 0.27 ENSDART00000090370
ENSDART00000192665
NADPH oxidase organizer 1a
chr23_-_28239750 0.26 ENSDART00000003548
zinc finger protein 385A
chr21_-_8513192 0.26 ENSDART00000084378
crumbs family member 2a
chr19_+_10832092 0.26 ENSDART00000191851
translocase of outer mitochondrial membrane 40 homolog, like
chr8_-_30791089 0.26 ENSDART00000147332
glutathione S-transferase theta 1a
chr12_+_10163585 0.26 ENSDART00000106191
proteasome 26S subunit, ATPase 5
chr8_+_471342 0.25 ENSDART00000167205
nudix (nucleoside diphosphate linked moiety X)-type motif 12
chr5_-_4493502 0.25 ENSDART00000067593
ENSDART00000190221
zgc:153704
chr7_+_23875269 0.24 ENSDART00000101406
RAB39B, member RAS oncogene family b
chr21_+_6961635 0.24 ENSDART00000137281
si:ch211-93g21.2
chr5_+_23256187 0.24 ENSDART00000168717
ENSDART00000142915
si:dkey-125i10.3
chr6_+_28205284 0.23 ENSDART00000160707
ENSDART00000190509
smx5
si:ch73-14h10.2
chr9_+_41024973 0.23 ENSDART00000014660
ENSDART00000144467
ORMDL sphingolipid biosynthesis regulator 1
chr2_+_47582681 0.23 ENSDART00000187579
secretogranin II (chromogranin C), b
chr13_-_32635859 0.22 ENSDART00000146249
ENSDART00000145395
ENSDART00000148040
ENSDART00000100650
matrilin 3b
chr24_+_14713776 0.22 ENSDART00000134475
ganglioside induced differentiation associated protein 1
chr7_+_11543999 0.22 ENSDART00000173676
interleukin 16
chr16_-_43025885 0.22 ENSDART00000193146
ENSDART00000157302
si:dkey-7j14.5
chr13_+_4205724 0.21 ENSDART00000134105
delta-like 2 homolog (Drosophila)
chr21_-_4032650 0.21 ENSDART00000151648
netrin g2b
chr12_+_28854410 0.21 ENSDART00000152991
nuclear factor, erythroid 2-like 1b
chr23_+_4299887 0.21 ENSDART00000132604
l(3)mbt-like 1a (Drosophila)
chr21_+_22423286 0.20 ENSDART00000133190
calcyphosine-like b
chr1_+_36651059 0.20 ENSDART00000187475
endothelin receptor type Aa
chr8_+_68864 0.19 ENSDART00000164574
proline rich 16
chr5_+_28973264 0.19 ENSDART00000005638
syntaxin binding protein 1b
chr23_+_43255328 0.18 ENSDART00000102712
transglutaminase 2, C polypeptide A
chr21_-_4244514 0.18 ENSDART00000065880
uridine-cytidine kinase 1
chr16_+_24681177 0.18 ENSDART00000058956
ENSDART00000189335
tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta polypeptide like
chr5_+_28972935 0.18 ENSDART00000193274
syntaxin binding protein 1b
chr7_-_38638809 0.18 ENSDART00000144341
six-cysteine containing astacin protease 4
chr16_+_34479064 0.18 ENSDART00000159965
si:ch211-255i3.4
chr13_-_40726865 0.18 ENSDART00000099847
ST3 beta-galactoside alpha-2,3-sialyltransferase 7
chr8_-_18239494 0.18 ENSDART00000079989
ENSDART00000022959
guanylate kinase 1b
chr20_-_26929685 0.17 ENSDART00000132556
finTRIM family, member 79
chr6_-_32314913 0.17 ENSDART00000051779
autophagy related 4C, cysteine peptidase
chr11_-_21014572 0.17 ENSDART00000042220
solute carrier family 6 (amino acid transporter), member 14
chr7_-_5316901 0.16 ENSDART00000181505
ENSDART00000124367
si:cabz01074946.1
chr1_+_20635190 0.16 ENSDART00000145418
ENSDART00000148518
ENSDART00000139461
ENSDART00000102969
ENSDART00000166479
sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 3
chr3_-_58798377 0.16 ENSDART00000161248
si:ch73-281f12.4
chr15_+_42559910 0.16 ENSDART00000075785
claudin 17
chr8_+_23009662 0.16 ENSDART00000030885
uridine-cytidine kinase 1-like 1a
chr6_+_27146671 0.16 ENSDART00000156792
kinesin family member 1Aa
chr2_-_13216269 0.15 ENSDART00000149947
BCL2, apoptosis regulator b
chr19_+_9004256 0.15 ENSDART00000186401
ENSDART00000091443
si:ch211-81a5.1
chr2_+_35854242 0.15 ENSDART00000134918
DEAH (Asp-Glu-Ala-His) box helicase 9
chr18_-_14691727 0.15 ENSDART00000010129
peptide deformylase, mitochondrial
chr5_-_6508250 0.15 ENSDART00000060535
crystallin, beta B3
chr2_+_47582488 0.15 ENSDART00000149967
secretogranin II (chromogranin C), b
chr9_-_23944470 0.15 ENSDART00000138754
collagen, type VI, alpha 3
chr1_+_44127292 0.14 ENSDART00000160542
calcium binding protein 2a
chr2_+_44545912 0.14 ENSDART00000155362
si:dkeyp-94h10.5
chr2_-_32551178 0.14 ENSDART00000145603
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 3a
chr3_-_32611833 0.14 ENSDART00000151282
si:ch73-248e21.5
chr17_-_20897250 0.14 ENSDART00000088106
ankyrin 3b
chr1_+_52518176 0.14 ENSDART00000003278
tachykinin receptor 3-like
chr7_+_57677120 0.14 ENSDART00000110623
arylsulfatase family, member J
chr7_-_32599669 0.14 ENSDART00000173752
potassium voltage-gated channel, shaker-related subfamily, member 4
chr8_-_23573084 0.14 ENSDART00000139084
Wiskott-Aldrich syndrome (eczema-thrombocytopenia) b
chr6_-_10964083 0.13 ENSDART00000181583
notum pectinacetylesterase 2
chr3_+_55105066 0.13 ENSDART00000110848
si:ch211-5k11.8
chr20_+_49119633 0.13 ENSDART00000151435
CD109 molecule
chr12_-_10275320 0.13 ENSDART00000170078
membrane protein, palmitoylated 2b (MAGUK p55 subfamily member 2)
chr5_+_33281105 0.13 ENSDART00000011337
surfeit 1
chr21_-_40083432 0.12 ENSDART00000141160
ENSDART00000191195
info solute carrier family 13 (sodium-dependent citrate transporter), member 5a
chr25_-_13676682 0.12 ENSDART00000090226
zinc finger protein 319b
chr25_+_7671640 0.12 ENSDART00000145367
potassium inwardly-rectifying channel, subfamily J, member 11, like
chr11_+_38332419 0.12 ENSDART00000005864
si:dkey-166c18.1
chr22_+_21972824 0.12 ENSDART00000183708
ENSDART00000133739
guanine nucleotide binding protein (G protein), alpha 15 (Gq class), tandem duplicate 3
chr4_-_20118468 0.12 ENSDART00000078587
si:dkey-159a18.1
chr20_-_17259573 0.12 ENSDART00000166397

chr16_-_38001040 0.12 ENSDART00000133861
ENSDART00000138711
ENSDART00000143846
ENSDART00000146564
si:ch211-198c19.3
chr5_+_21931124 0.12 ENSDART00000137627
si:ch73-92i20.1
chr6_-_13200585 0.11 ENSDART00000185321
eukaryotic translation elongation factor 1 beta 2
chr1_-_49544601 0.11 ENSDART00000145960
solute carrier family 47 (multidrug and toxin extrusion), member 2.2
chr3_+_38793499 0.11 ENSDART00000083394
potassium voltage-gated channel subfamily J member 19a
chr15_+_5321612 0.11 ENSDART00000174345
odorant receptor, family A, subfamily 113, member 1
chr4_+_25607743 0.11 ENSDART00000028297
acyl-CoA thioesterase 14
chr1_+_55239710 0.10 ENSDART00000174846
si:ch211-286b5.2
chr25_-_6557854 0.10 ENSDART00000181740
chondroitin sulfate proteoglycan 4
chr6_-_10912424 0.10 ENSDART00000036456
cytochrome c, somatic b
chr18_-_29961784 0.10 ENSDART00000135601
ENSDART00000140661
si:ch73-103b9.2
chr22_+_17192767 0.10 ENSDART00000130810
ENSDART00000183006
ATP synthase mitochondrial F1 complex assembly factor 1
chr9_-_32730487 0.10 ENSDART00000147795
oligodendrocyte transcription factor 1
chr17_+_24006792 0.10 ENSDART00000122415
si:ch211-63b16.4
chr2_-_4797512 0.10 ENSDART00000160765
tyrosine kinase, non-receptor, 2b
chr22_+_35516440 0.10 ENSDART00000184191
hydroxylysine kinase, tandem duplicate 2
chr2_-_36932253 0.10 ENSDART00000124217
microtubule-associated protein 1Sb
chr23_+_44644911 0.09 ENSDART00000140799
zgc:85858
chr25_-_35996141 0.09 ENSDART00000149074
spalt-like transcription factor 1b
chr20_-_5267600 0.09 ENSDART00000099258
cytochrome P450, family 46, subfamily A, polypeptide 1, tandem duplicate 4
chr15_+_5973909 0.09 ENSDART00000126886
ENSDART00000189618
immunoglobulin superfamily, member 5b
chr25_-_36286186 0.09 ENSDART00000182398
solute carrier family 7 (neutral amino acid transporter light chain, asc system), member 10b
chr16_-_19349318 0.09 ENSDART00000020821
dynein, axonemal, heavy chain 11
chr5_+_69868911 0.09 ENSDART00000014649
ENSDART00000188215
ENSDART00000167385
UDP glucuronosyltransferase 2 family, polypeptide A5
chr6_+_612330 0.09 ENSDART00000166872
ENSDART00000191758
kynureninase
chr2_-_6039757 0.09 ENSDART00000013079
sterol carrier protein 2a
chr16_+_40508882 0.09 ENSDART00000126129
N-acetylglucosamine-1-phosphodiester alpha-N-acetylglucosaminidase
chr6_-_10963887 0.08 ENSDART00000151102
notum pectinacetylesterase 2
chr10_+_3875716 0.08 ENSDART00000189268
ENSDART00000180624
tetratricopeptide repeat domain 28
chr2_-_11504347 0.08 ENSDART00000019392
short chain dehydrogenase/reductase family 16C, member 5a
chr25_+_25438322 0.08 ENSDART00000150364
si:ch211-103e16.5
chr23_+_19606291 0.08 ENSDART00000139415
filamin B, beta (actin binding protein 278)
chr17_-_51938663 0.08 ENSDART00000179784
ergosterol biosynthesis 28 homolog
chr4_-_69917450 0.08 ENSDART00000168915
zinc finger protein 1076
chr18_-_34156765 0.08 ENSDART00000059400
c18h3orf33 homolog (H. sapiens)
chr14_-_33360344 0.07 ENSDART00000181291
Pim proto-oncogene, serine/threonine kinase, related 117
chr11_-_40101246 0.07 ENSDART00000161083
tumor necrosis factor receptor superfamily, member 9b
chr22_+_10781894 0.07 ENSDART00000081183
ectodermal-neural cortex 3
chr3_+_32099507 0.07 ENSDART00000044238
zgc:92066
chr14_-_28568107 0.07 ENSDART00000042850
ENSDART00000145502
preproinsulin b
chr12_+_9761685 0.07 ENSDART00000189522
protein phosphatase 1, regulatory subunit 9Bb
chr3_+_27786601 0.07 ENSDART00000086994
N-acetyltransferase 15 (GCN5-related, putative)
chr7_-_18656069 0.07 ENSDART00000021559
coronin, actin binding protein, 1B
chr22_+_1887750 0.07 ENSDART00000180917
si:dkey-15h8.17
chr17_-_20897407 0.06 ENSDART00000149481
ankyrin 3b
chr13_-_44738574 0.06 ENSDART00000074761
zinc finger, AN1-type domain 3
chr15_-_24178893 0.06 ENSDART00000077980
pipecolic acid oxidase
chr7_+_39624728 0.06 ENSDART00000173847
ENSDART00000173845
protein tyrosine phosphatase, non-receptor type 5
chr6_-_10776254 0.06 ENSDART00000184008
G protein-coupled receptor 155b
chr10_+_20630444 0.06 ENSDART00000191182
prion protein b
chr22_-_8725768 0.06 ENSDART00000189873
ENSDART00000181819
si:ch73-27e22.1
si:ch73-27e22.8
chr4_-_29753895 0.06 ENSDART00000150742
si:dkey-191j3.1
chr7_+_22702437 0.06 ENSDART00000182054
si:dkey-165a24.9
chr7_+_65272470 0.06 ENSDART00000162471
beta-carotene oxygenase 1
chr3_-_2589704 0.06 ENSDART00000187239
si:dkey-217f16.5
chr12_-_17199381 0.06 ENSDART00000193292
lipase, gastric
chr24_+_2961098 0.06 ENSDART00000163760
ENSDART00000170835
enoyl-CoA delta isomerase 2
chr25_-_3759322 0.06 ENSDART00000088077
zgc:158398
chr10_+_1899595 0.06 ENSDART00000040271

chr5_-_22621417 0.05 ENSDART00000138716
zgc:113208
chr21_+_21339311 0.05 ENSDART00000137693
ENSDART00000161820
succinate dehydrogenase complex assembly factor 1
si:ch211-191j22.3
chr14_-_26400501 0.05 ENSDART00000054189
Pim proto-oncogene, serine/threonine kinase, related 212
chr1_+_15226268 0.05 ENSDART00000109911
heparan-alpha-glucosaminide N-acetyltransferase
chr12_-_11649690 0.05 ENSDART00000149713
BTB (POZ) domain containing 16
chr23_+_14590767 0.05 ENSDART00000143675
si:rp71-79p20.2
chr17_+_53284040 0.05 ENSDART00000165368
ataxin 3
chr25_+_10947743 0.05 ENSDART00000073381
major histocompatibility complex class I LFA
chr4_-_42391176 0.05 ENSDART00000189739
si:ch211-59d8.2
chr6_+_14980761 0.05 ENSDART00000087782
mitochondrial ribosomal protein S9
chr24_-_25186895 0.05 ENSDART00000081029
phosphatidylinositol-specific phospholipase C, X domain containing 2

Network of associatons between targets according to the STRING database.

First level regulatory network of irx2a

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.6 GO:0097435 fibril organization(GO:0097435)
0.1 0.4 GO:0014809 regulation of skeletal muscle contraction by calcium ion signaling(GO:0014722) regulation of skeletal muscle contraction by regulation of release of sequestered calcium ion(GO:0014809)
0.1 0.5 GO:0019401 glycerol biosynthetic process(GO:0006114) alditol biosynthetic process(GO:0019401) short-chain fatty acid catabolic process(GO:0019626) response to dexamethasone(GO:0071548)
0.1 0.6 GO:0021846 cell proliferation in forebrain(GO:0021846)
0.1 0.3 GO:1902571 regulation of serine-type peptidase activity(GO:1902571)
0.1 0.4 GO:0019254 carnitine metabolic process, CoA-linked(GO:0019254)
0.1 0.3 GO:0072526 pyridine nucleotide catabolic process(GO:0019364) NAD catabolic process(GO:0019677) pyridine-containing compound catabolic process(GO:0072526)
0.1 0.2 GO:0090155 regulation of sphingolipid biosynthetic process(GO:0090153) negative regulation of sphingolipid biosynthetic process(GO:0090155) negative regulation of ceramide biosynthetic process(GO:1900060) regulation of membrane lipid metabolic process(GO:1905038) regulation of ceramide biosynthetic process(GO:2000303)
0.1 0.3 GO:0033353 S-adenosylmethionine cycle(GO:0033353)
0.1 0.3 GO:2001223 negative regulation of neuron migration(GO:2001223)
0.1 0.3 GO:0010133 proline catabolic process to glutamate(GO:0010133)
0.1 0.2 GO:1990697 protein depalmitoleylation(GO:1990697)
0.1 0.5 GO:0032096 negative regulation of response to food(GO:0032096) negative regulation of appetite(GO:0032099)
0.0 0.4 GO:0006878 cellular copper ion homeostasis(GO:0006878)
0.0 0.3 GO:0045898 regulation of RNA polymerase II transcriptional preinitiation complex assembly(GO:0045898) positive regulation of RNA polymerase II transcriptional preinitiation complex assembly(GO:0045899)
0.0 0.3 GO:0044211 CTP salvage(GO:0044211)
0.0 0.1 GO:0033615 mitochondrial proton-transporting ATP synthase complex assembly(GO:0033615)
0.0 0.5 GO:0048385 regulation of retinoic acid receptor signaling pathway(GO:0048385)
0.0 0.2 GO:0035176 social behavior(GO:0035176) intraspecies interaction between organisms(GO:0051703)
0.0 0.1 GO:0042940 D-amino acid transport(GO:0042940) D-alanine transport(GO:0042941) D-serine transport(GO:0042942)
0.0 0.2 GO:2000480 negative regulation of cAMP-dependent protein kinase activity(GO:2000480)
0.0 0.4 GO:0006596 polyamine biosynthetic process(GO:0006596)
0.0 0.1 GO:0097052 L-kynurenine metabolic process(GO:0097052) L-kynurenine catabolic process(GO:0097053)
0.0 0.2 GO:0018206 peptidyl-methionine modification(GO:0018206)
0.0 0.3 GO:0046548 retinal rod cell development(GO:0046548)
0.0 0.3 GO:0007035 vacuolar acidification(GO:0007035) pH reduction(GO:0045851) intracellular pH reduction(GO:0051452)
0.0 0.6 GO:0006446 regulation of translational initiation(GO:0006446)
0.0 0.6 GO:0006783 heme biosynthetic process(GO:0006783)
0.0 0.1 GO:1902093 positive regulation of sperm motility(GO:1902093)
0.0 0.3 GO:0032438 melanosome organization(GO:0032438)
0.0 0.5 GO:0007286 spermatid development(GO:0007286)
0.0 0.1 GO:0032370 positive regulation of lipid transport(GO:0032370)
0.0 0.7 GO:1903670 regulation of sprouting angiogenesis(GO:1903670)
0.0 0.1 GO:0006337 nucleosome disassembly(GO:0006337) chromatin disassembly(GO:0031498) protein-DNA complex disassembly(GO:0032986)
0.0 0.1 GO:0019477 lysine catabolic process(GO:0006554) L-lysine catabolic process to acetyl-CoA(GO:0019474) L-lysine catabolic process(GO:0019477) L-lysine metabolic process(GO:0046440)
0.0 0.5 GO:0045746 negative regulation of Notch signaling pathway(GO:0045746)
0.0 0.2 GO:0008053 mitochondrial fusion(GO:0008053)
0.0 0.3 GO:0030150 protein import into mitochondrial matrix(GO:0030150)
0.0 0.5 GO:0006749 glutathione metabolic process(GO:0006749)
0.0 0.3 GO:0000028 ribosomal small subunit assembly(GO:0000028)
0.0 0.4 GO:0006891 intra-Golgi vesicle-mediated transport(GO:0006891)
0.0 0.1 GO:0006842 tricarboxylic acid transport(GO:0006842) citrate transport(GO:0015746)
0.0 0.1 GO:0016338 calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules(GO:0016338)
0.0 0.2 GO:0050926 regulation of positive chemotaxis(GO:0050926) positive regulation of positive chemotaxis(GO:0050927) induction of positive chemotaxis(GO:0050930)
0.0 0.1 GO:0034553 respiratory chain complex II assembly(GO:0034552) mitochondrial respiratory chain complex II assembly(GO:0034553) mitochondrial respiratory chain complex II biogenesis(GO:0097032)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.5 GO:0016012 sarcoglycan complex(GO:0016012)
0.1 0.3 GO:0060171 stereocilium membrane(GO:0060171)
0.1 0.4 GO:0033018 sarcoplasmic reticulum lumen(GO:0033018)
0.1 0.2 GO:0035339 SPOTS complex(GO:0035339)
0.0 0.2 GO:1990726 Lsm1-7-Pat1 complex(GO:1990726)
0.0 0.3 GO:0000220 vacuolar proton-transporting V-type ATPase, V0 domain(GO:0000220)
0.0 0.3 GO:0031597 cytosolic proteasome complex(GO:0031597)
0.0 1.0 GO:0048770 melanosome(GO:0042470) pigment granule(GO:0048770)
0.0 0.3 GO:0005742 mitochondrial outer membrane translocase complex(GO:0005742)
0.0 0.2 GO:0031307 integral component of mitochondrial outer membrane(GO:0031307)
0.0 0.1 GO:0097225 sperm midpiece(GO:0097225)
0.0 0.1 GO:0005853 eukaryotic translation elongation factor 1 complex(GO:0005853)
0.0 0.3 GO:0005640 nuclear outer membrane(GO:0005640)
0.0 0.3 GO:0044327 dendritic spine head(GO:0044327)
0.0 1.0 GO:0030141 secretory granule(GO:0030141)
0.0 0.1 GO:0031838 haptoglobin-hemoglobin complex(GO:0031838)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.6 GO:0004311 farnesyltranstransferase activity(GO:0004311)
0.2 0.5 GO:0004174 electron-transferring-flavoprotein dehydrogenase activity(GO:0004174) oxidoreductase activity, acting on the CH-NH group of donors, quinone or similar compound as acceptor(GO:0016649)
0.1 0.3 GO:0016802 adenosylhomocysteinase activity(GO:0004013) trialkylsulfonium hydrolase activity(GO:0016802)
0.1 0.4 GO:0008073 ornithine decarboxylase inhibitor activity(GO:0008073)
0.1 0.4 GO:0004092 carnitine O-acetyltransferase activity(GO:0004092)
0.1 0.4 GO:0016531 copper chaperone activity(GO:0016531)
0.1 0.6 GO:0008494 translation activator activity(GO:0008494)
0.1 0.3 GO:0004657 proline dehydrogenase activity(GO:0004657)
0.1 0.2 GO:0047291 lactosylceramide alpha-2,3-sialyltransferase activity(GO:0047291)
0.1 0.2 GO:1990699 palmitoleyl hydrolase activity(GO:1990699)
0.1 0.3 GO:0035529 NADH pyrophosphatase activity(GO:0035529)
0.0 0.2 GO:0042609 CD4 receptor binding(GO:0042609)
0.0 0.3 GO:0004849 uridine kinase activity(GO:0004849)
0.0 0.2 GO:0004385 guanylate kinase activity(GO:0004385)
0.0 0.3 GO:0004865 protein serine/threonine phosphatase inhibitor activity(GO:0004865)
0.0 0.1 GO:0017153 sodium:dicarboxylate symporter activity(GO:0017153)
0.0 0.3 GO:0016176 superoxide-generating NADPH oxidase activator activity(GO:0016176)
0.0 0.2 GO:0004862 cAMP-dependent protein kinase inhibitor activity(GO:0004862)
0.0 0.2 GO:0004962 endothelin receptor activity(GO:0004962)
0.0 0.3 GO:0061575 cyclin-dependent protein serine/threonine kinase activator activity(GO:0061575)
0.0 0.9 GO:0004364 glutathione transferase activity(GO:0004364)
0.0 0.6 GO:0043236 laminin binding(GO:0043236)
0.0 0.4 GO:0038191 neuropilin binding(GO:0038191)
0.0 0.3 GO:0051117 ATPase binding(GO:0051117)
0.0 0.1 GO:0004995 tachykinin receptor activity(GO:0004995)
0.0 0.1 GO:0016822 hydrolase activity, acting on acid carbon-carbon bonds(GO:0016822) hydrolase activity, acting on acid carbon-carbon bonds, in ketonic substances(GO:0016823)
0.0 0.3 GO:0008320 protein transmembrane transporter activity(GO:0008320)
0.0 0.5 GO:0004675 transmembrane receptor protein serine/threonine kinase activity(GO:0004675)
0.0 0.1 GO:0019202 amino acid kinase activity(GO:0019202)
0.0 0.1 GO:0033781 cholesterol 24-hydroxylase activity(GO:0033781)
0.0 0.1 GO:0031826 type 2A serotonin receptor binding(GO:0031826)
0.0 0.4 GO:0051020 GTPase binding(GO:0051020)
0.0 0.5 GO:0030145 manganese ion binding(GO:0030145)
0.0 0.1 GO:0031420 potassium ion binding(GO:0030955) alkali metal ion binding(GO:0031420)
0.0 0.1 GO:0015467 G-protein activated inward rectifier potassium channel activity(GO:0015467)
0.0 0.3 GO:0051428 peptide hormone receptor binding(GO:0051428)
0.0 0.1 GO:0031720 haptoglobin binding(GO:0031720)
0.0 0.1 GO:0016647 oxidoreductase activity, acting on the CH-NH group of donors, oxygen as acceptor(GO:0016647)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.4 NABA PROTEOGLYCANS Genes encoding proteoglycans

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.3 REACTOME HS GAG BIOSYNTHESIS Genes involved in HS-GAG biosynthesis
0.0 0.2 REACTOME TIGHT JUNCTION INTERACTIONS Genes involved in Tight junction interactions
0.0 0.1 REACTOME THE ACTIVATION OF ARYLSULFATASES Genes involved in The activation of arylsulfatases
0.0 0.2 REACTOME NA CL DEPENDENT NEUROTRANSMITTER TRANSPORTERS Genes involved in Na+/Cl- dependent neurotransmitter transporters
0.0 0.3 REACTOME GLUCONEOGENESIS Genes involved in Gluconeogenesis