Project

PRJNA195909:zebrafish embryo and larva development

Navigation
Downloads

Results for irx1b+irx4a+irx4b

Z-value: 0.64

Motif logo

logo of

Transcription factors associated with irx1b+irx4a+irx4b

Gene Symbol Gene ID Gene Info
irx4a
ENSDARG00000035648 iroquois homeobox 4a
irx4b
ENSDARG00000036051 iroquois homeobox 4b
irx1b
ENSDARG00000056594 iroquois homeobox 1b

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
irx4adr11_v1_chr16_-_383664_383664-0.844.2e-03Click!
irx4bdr11_v1_chr19_+_28116410_28116410-0.771.6e-02Click!
irx1bdr11_v1_chr19_-_28130658_281306580.235.6e-01Click!

Activity profile of irx1b+irx4a+irx4b motif

Sorted Z-values of irx1b+irx4a+irx4b motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr7_+_56577906 1.06 ENSDART00000184023
hp
haptoglobin
chr10_-_45002196 0.94 ENSDART00000170767
ved
ventrally expressed dharma/bozozok antagonist
chr25_-_29072162 0.74 ENSDART00000169269
arid3b
AT rich interactive domain 3B (BRIGHT-like)
chr5_+_66170479 0.73 ENSDART00000172117
gldc
glycine dehydrogenase (decarboxylating)
chr7_+_56577522 0.71 ENSDART00000149130
ENSDART00000149624
hp
haptoglobin
chr18_+_22109379 0.70 ENSDART00000147230
zgc:158868
zgc:158868
chr10_+_8629275 0.57 ENSDART00000129643
aplnrb
apelin receptor b
chr21_-_45871866 0.55 ENSDART00000161716
larp1
La ribonucleoprotein domain family, member 1
chr14_-_10617127 0.54 ENSDART00000154299
si:dkey-92i17.2
si:dkey-92i17.2
chr17_-_5352924 0.36 ENSDART00000167275
supt3h
SPT3 homolog, SAGA and STAGA complex component
chr3_-_402714 0.35 ENSDART00000134062
ENSDART00000105659
mhc1zja
major histocompatibility complex class I ZJA
chr10_-_28117740 0.34 ENSDART00000134491
med13a
mediator complex subunit 13a
chr2_-_7185460 0.33 ENSDART00000092078
rc3h1b
ring finger and CCCH-type domains 1b
chr8_+_23784471 0.33 ENSDART00000189457
si:ch211-163l21.8
si:ch211-163l21.8
chr5_-_58996324 0.31 ENSDART00000033923
mis12
MIS12 kinetochore complex component
chr20_-_27190393 0.30 ENSDART00000149024
btbd7
BTB (POZ) domain containing 7
chr14_-_26392146 0.29 ENSDART00000037999
b4galt7
xylosylprotein beta 1,4-galactosyltransferase, polypeptide 7 (galactosyltransferase I)
chr5_-_35159379 0.27 ENSDART00000144105
fcho2
FCH domain only 2
chr8_-_23783633 0.20 ENSDART00000132657
si:ch211-163l21.7
si:ch211-163l21.7
chr23_+_40275400 0.18 ENSDART00000184259
fam46ab
family with sequence similarity 46, member Ab
chr23_+_19701587 0.17 ENSDART00000104425
dnase1l1
deoxyribonuclease I-like 1
chr8_+_26410197 0.15 ENSDART00000145836
ENSDART00000053447
ifrd2
interferon-related developmental regulator 2
chr23_+_45845159 0.15 ENSDART00000023944
lmnl3
lamin L3
chr22_+_1940595 0.15 ENSDART00000163506
znf1167
zinc finger protein 1167
chr6_-_34838397 0.14 ENSDART00000060169
ENSDART00000169605
mier1a
mesoderm induction early response 1a, transcriptional regulator
chr23_+_40275601 0.13 ENSDART00000076876
fam46ab
family with sequence similarity 46, member Ab
chr20_-_23440955 0.12 ENSDART00000153386
slc10a4
solute carrier family 10, member 4
chr21_+_12036238 0.12 ENSDART00000102463
ENSDART00000155426
zgc:162344
zgc:162344
chr9_-_2945008 0.12 ENSDART00000183452
zak
sterile alpha motif and leucine zipper containing kinase AZK
chr4_+_33012407 0.12 ENSDART00000151873
si:dkey-26h11.2
si:dkey-26h11.2
chr5_-_41103583 0.12 ENSDART00000051070
ENSDART00000074781
golph3
golgi phosphoprotein 3
chr13_-_43149063 0.11 ENSDART00000099601
vsir
V-set immunoregulatory receptor
chr4_-_5691257 0.10 ENSDART00000110497
tmem63a
transmembrane protein 63A
chr17_-_14705039 0.10 ENSDART00000154281
ENSDART00000123550
ptp4a2a
protein tyrosine phosphatase type IVA, member 2a
chr21_+_20549395 0.10 ENSDART00000181633
efna5a
ephrin-A5a
chr18_+_5549672 0.09 ENSDART00000184970
nnt2
nicotinamide nucleotide transhydrogenase 2
chr1_+_53919110 0.09 ENSDART00000020680
nup133
nucleoporin 133
chr15_+_17100412 0.09 ENSDART00000154418
relb
v-rel avian reticuloendotheliosis viral oncogene homolog B
chr21_+_43882274 0.08 ENSDART00000075672
sra1
steroid receptor RNA activator 1
chr15_-_41734639 0.07 ENSDART00000154230
ENSDART00000167443
ftr90
finTRIM family, member 90
chr23_+_45845423 0.07 ENSDART00000183404
lmnl3
lamin L3
chr10_-_22912255 0.05 ENSDART00000131992
si:ch1073-143l10.2
si:ch1073-143l10.2
chr22_-_7778265 0.05 ENSDART00000097276
si:ch73-44m9.3
si:ch73-44m9.3
chr1_-_7951002 0.04 ENSDART00000138187
si:dkey-79f11.8
si:dkey-79f11.8
chr6_-_43262400 0.04 ENSDART00000156267
frmd4ba
FERM domain containing 4Ba
chr1_+_961607 0.04 ENSDART00000184660
n6amt1
N-6 adenine-specific DNA methyltransferase 1
chr8_-_11832771 0.03 ENSDART00000193412
ENSDART00000184720
ENSDART00000139947
rapgef1a
Rap guanine nucleotide exchange factor (GEF) 1a
chr16_-_44709832 0.02 ENSDART00000156784
si:ch211-151m7.6
si:ch211-151m7.6
chr15_+_37331585 0.02 ENSDART00000170715
zgc:171592
zgc:171592
chr5_+_34578479 0.01 ENSDART00000016314
gfm2
G elongation factor, mitochondrial 2
chr15_+_11381532 0.00 ENSDART00000124172
si:ch73-321d9.2
si:ch73-321d9.2

Network of associatons between targets according to the STRING database.

First level regulatory network of irx1b+irx4a+irx4b

PNG image of the network

In order to view interactive SVG image please either update your browser to latest version or install SVG plugin.
View svg image
View png image

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.7 GO:0019464 glycine catabolic process(GO:0006546) glycine decarboxylation via glycine cleavage system(GO:0019464)
0.1 0.6 GO:1903589 regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis(GO:1903587) positive regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis(GO:1903589)
0.1 0.9 GO:0042661 regulation of mesodermal cell fate specification(GO:0042661)
0.0 0.3 GO:0044090 positive regulation of vacuole organization(GO:0044090)
0.0 0.3 GO:0034501 protein localization to kinetochore(GO:0034501) protein localization to chromosome, centromeric region(GO:0071459)
0.0 0.1 GO:0006740 NADPH regeneration(GO:0006740)
0.0 0.1 GO:0000972 transcription-dependent tethering of RNA polymerase II gene DNA at nuclear periphery(GO:0000972)
0.0 0.1 GO:0039703 viral genome replication(GO:0019079) negative stranded viral RNA replication(GO:0039689) viral RNA genome replication(GO:0039694) RNA replication(GO:0039703) multi-organism biosynthetic process(GO:0044034)
0.0 0.2 GO:0000737 DNA catabolic process, endonucleolytic(GO:0000737)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.7 GO:0005960 glycine cleavage complex(GO:0005960)
0.1 0.3 GO:0000818 nuclear MIS12/MIND complex(GO:0000818)
0.1 0.4 GO:0030914 STAGA complex(GO:0030914)
0.0 0.1 GO:0031233 intrinsic component of external side of plasma membrane(GO:0031233) anchored component of external side of plasma membrane(GO:0031362)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.6 GO:0060182 apelin receptor activity(GO:0060182)
0.1 0.7 GO:0016594 glycine binding(GO:0016594)
0.0 0.3 GO:0035613 RNA stem-loop binding(GO:0035613)
0.0 0.1 GO:0016652 NAD(P)+ transhydrogenase activity(GO:0008746) oxidoreductase activity, acting on NAD(P)H, NAD(P) as acceptor(GO:0016652)
0.0 0.3 GO:0035250 UDP-galactosyltransferase activity(GO:0035250)
0.0 0.1 GO:0008508 bile acid:sodium symporter activity(GO:0008508)
0.0 0.2 GO:0004530 deoxyribonuclease I activity(GO:0004530)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.4 PID MYC PATHWAY C-MYC pathway
0.0 0.1 PID P38 GAMMA DELTA PATHWAY Signaling mediated by p38-gamma and p38-delta

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.3 REACTOME A TETRASACCHARIDE LINKER SEQUENCE IS REQUIRED FOR GAG SYNTHESIS Genes involved in A tetrasaccharide linker sequence is required for GAG synthesis