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PRJNA195909:zebrafish embryo and larva development

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Results for irf5

Z-value: 2.58

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Transcription factors associated with irf5

Gene Symbol Gene ID Gene Info
ENSDARG00000045681 interferon regulatory factor 5

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
irf5dr11_v1_chr4_-_13614797_136149360.853.6e-03Click!

Activity profile of irf5 motif

Sorted Z-values of irf5 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr7_+_69187585 5.26 ENSDART00000160499
ENSDART00000166258
MARVEL domain containing 3
chr20_-_43743700 3.53 ENSDART00000100620
si:dkeyp-50f7.2
chr15_+_44201056 3.40 ENSDART00000162433
ENSDART00000148336

chr5_-_30382925 3.36 ENSDART00000125381
grass carp reovirus (GCRV)-induced gene 2o
chr22_+_24623936 3.30 ENSDART00000160924
mucolipin 2
chr7_+_46020508 3.03 ENSDART00000170294
cyclin E1
chr15_-_29162193 2.85 ENSDART00000138449
ENSDART00000099885
XIAP associated factor 1
chr15_-_33964897 2.83 ENSDART00000172075
ENSDART00000158126
ENSDART00000160456
lipolysis stimulated lipoprotein receptor
chr17_+_22381215 2.82 ENSDART00000162670
ENSDART00000128875
solute carrier family 8 (sodium/calcium exchanger), member 1b
chr18_+_44532668 2.78 ENSDART00000140672
suppression of tumorigenicity 14 (colon carcinoma) a
chr14_+_32918484 2.68 ENSDART00000105721
ligand of numb-protein X 2b
chr15_+_25452092 2.62 ENSDART00000009545
p21 protein (Cdc42/Rac)-activated kinase 4
chr14_-_41467497 2.59 ENSDART00000181220
MID1 interacting protein 1, like
chr13_-_37631092 2.51 ENSDART00000108855
si:dkey-188i13.7
chr18_+_44532199 2.50 ENSDART00000135386
suppression of tumorigenicity 14 (colon carcinoma) a
chr13_-_23051766 2.49 ENSDART00000111774
SUV3-like helicase
chr18_+_44532370 2.45 ENSDART00000086952
suppression of tumorigenicity 14 (colon carcinoma) a
chr21_+_21010786 2.36 ENSDART00000079692
nodal-related 1
chr25_+_28862660 2.36 ENSDART00000154681
si:ch211-106e7.2
chr5_+_57442271 2.32 ENSDART00000097395
PRP4 pre-mRNA processing factor 4 homolog (yeast)
chr20_+_6535438 2.29 ENSDART00000145763
si:ch211-191a24.4
chr25_+_15997957 2.26 ENSDART00000140047
PTPRF interacting protein, binding protein 2b (liprin beta 2)
chr24_-_34680956 2.26 ENSDART00000171009
catenin (cadherin-associated protein), alpha 1
chr5_+_57726425 2.25 ENSDART00000134684
ferredoxin-fold anticodon binding domain containing 1
chr20_+_6535176 2.25 ENSDART00000054652
si:ch211-191a24.4
chr15_+_44184367 2.25 ENSDART00000162918
ENSDART00000110060
zgc:165514
chr19_+_42227400 2.22 ENSDART00000131574
ENSDART00000135436
jumping translocation breakpoint
chr14_-_33278084 2.22 ENSDART00000132850
START domain containing 14
chr17_+_30894431 2.21 ENSDART00000127996
delta(4)-desaturase, sphingolipid 2
chr1_-_55750208 2.12 ENSDART00000142244
DnaJ (Hsp40) homolog, subfamily B, member 1b
chr11_-_40257225 2.09 ENSDART00000139009
si:ch211-193i15.2
chr7_-_9717020 2.01 ENSDART00000029668
leucine-rich repeat kinase 1
chr9_+_41459759 2.01 ENSDART00000132501
ENSDART00000100265
nuclear envelope integral membrane protein 2
chr2_-_21438492 1.97 ENSDART00000046098
phospholipase C, delta 1b
chr23_+_2666944 1.97 ENSDART00000192861

chr3_-_36127234 1.93 ENSDART00000130917
coilin p80
chr25_+_16646113 1.89 ENSDART00000110426
cat eye syndrome chromosome region, candidate 2
chr18_+_44532883 1.89 ENSDART00000121994
suppression of tumorigenicity 14 (colon carcinoma) a
chr10_-_15879569 1.87 ENSDART00000136789
tight junction protein 2a (zona occludens 2)
chr23_-_10745288 1.87 ENSDART00000140745
ENSDART00000013768
eukaryotic translation initiation factor 4E family member 3
chr5_-_29531948 1.86 ENSDART00000098360
arrestin domain containing 1a
chr19_+_4968947 1.85 ENSDART00000003634
ENSDART00000134808
StAR-related lipid transfer (START) domain containing 3
chr22_-_17688868 1.82 ENSDART00000012336
ENSDART00000147070
tight junction protein 3
chr25_+_20272145 1.82 ENSDART00000109605
si:dkey-219c3.2
chr7_+_19600262 1.79 ENSDART00000007310
zgc:171731
chr14_-_33277743 1.78 ENSDART00000048130
START domain containing 14
chr24_-_26885897 1.76 ENSDART00000180512
fibronectin type III domain containing 3Bb
chr3_+_32571929 1.75 ENSDART00000151025
si:ch73-248e21.1
chr19_-_15420678 1.75 ENSDART00000151454
ENSDART00000027697
serine incorporator 2
chr9_+_3055566 1.74 ENSDART00000189906
ENSDART00000175891
ENSDART00000093021
protein phosphatase 1 regulatory subunit 9A-like A
chr5_-_67241633 1.70 ENSDART00000114783
CAP-GLY domain containing linker protein 1a
chr16_+_19637384 1.69 ENSDART00000184773
ENSDART00000191895
ENSDART00000182020
ENSDART00000135359
metastasis associated in colon cancer 1
chr5_+_58455488 1.67 ENSDART00000038602
ENSDART00000127958
solute carrier family 37 (glucose-6-phosphate transporter), member 2
chr12_+_17154655 1.65 ENSDART00000028003
ankyrin repeat domain 22
chr13_-_33700461 1.64 ENSDART00000160520
MAD2L1 binding protein
chr15_+_31911989 1.58 ENSDART00000111472
breast cancer 2, early onset
chr5_-_12587053 1.56 ENSDART00000162780
V-set and immunoglobulin domain containing 10
chr15_-_17071328 1.54 ENSDART00000122617
si:ch211-24o10.6
chr6_-_1566407 1.53 ENSDART00000112118
tripartite motif containing 107
chr16_-_41667101 1.52 ENSDART00000084528
ATPase secretory pathway Ca2+ transporting 1
chr11_+_39969048 1.52 ENSDART00000193693
period circadian clock 3
chr25_-_27665978 1.52 ENSDART00000123590
si:ch211-91p5.3
chr9_+_23765587 1.50 ENSDART00000145120
si:ch211-219a4.3
chr18_+_45666489 1.50 ENSDART00000180147
ENSDART00000151351
proline rich Gla (G-carboxyglutamic acid) 4 (transmembrane)
chr5_+_39099172 1.49 ENSDART00000006079
BMP2 inducible kinase
chr21_+_20903244 1.49 ENSDART00000186193
complement component 7b
chr10_-_22150419 1.49 ENSDART00000006173
claudin 7b
chr23_+_31942040 1.48 ENSDART00000088607
nuclear envelope integral membrane protein 1
chr5_+_50913357 1.47 ENSDART00000092938
collagen, type IV, alpha 3 (Goodpasture antigen) binding protein a
chr8_-_49304602 1.46 ENSDART00000147020
prickle homolog 3
chr15_-_1835189 1.46 ENSDART00000154369
TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor
chr6_-_1566581 1.46 ENSDART00000192993
tripartite motif containing 107
chr16_-_26525901 1.43 ENSDART00000110260
l(3)mbt-like 1b (Drosophila)
chr20_+_20751425 1.43 ENSDART00000177048
protein phosphatase 1, regulatory subunit 13Bb
chr25_-_12809361 1.42 ENSDART00000162750
carbonic anhydrase Va
chr3_+_36127287 1.40 ENSDART00000058605
ENSDART00000182500
serine carboxypeptidase 1
chr20_+_1316803 1.36 ENSDART00000152586
ENSDART00000152165
nucleoporin 43
chr10_+_35152928 1.36 ENSDART00000063418
NOP2/Sun domain family, member 5
chr8_-_19266325 1.35 ENSDART00000036148
ENSDART00000137994
zgc:77486
chr16_+_27383717 1.35 ENSDART00000132329
ENSDART00000136256
syntaxin 17
chr17_-_24879003 1.34 ENSDART00000123147
zinc finger and BTB domain containing 8A
chr12_+_24060894 1.34 ENSDART00000021298
ankyrin repeat and SOCS box containing 3
chr21_-_22122312 1.33 ENSDART00000101726
solute carrier family 35, member F2
chr2_+_34967022 1.32 ENSDART00000134926
astrotactin 1
chr19_+_9113932 1.32 ENSDART00000060442
SET domain, bifurcated 1a
chr18_+_37015185 1.32 ENSDART00000191305
signal-induced proliferation-associated 1 like 3
chr25_+_16080181 1.32 ENSDART00000061753
fatty acyl CoA reductase 1
chr9_+_17862858 1.30 ENSDART00000166566
diacylglycerol kinase, eta
chr9_+_32178374 1.30 ENSDART00000078576
coenzyme Q10B
chr20_+_13783040 1.29 ENSDART00000115329
ENSDART00000152497
lysophosphatidylglycerol acyltransferase 1
chr22_+_32235922 1.29 ENSDART00000114531
ENSDART00000136125
RNA binding motif protein 15B
chr14_-_31814149 1.29 ENSDART00000173393
Rac/Cdc42 guanine nucleotide exchange factor (GEF) 6
chr5_+_39099380 1.27 ENSDART00000166657
BMP2 inducible kinase
chr10_+_4046448 1.26 ENSDART00000123086
ENSDART00000052268
phosphatidylinositol transfer protein, beta
chr23_-_29553430 1.26 ENSDART00000157773
ENSDART00000126384
ubiquitination factor E4B, UFD2 homolog (S. cerevisiae)
chr25_+_16079913 1.26 ENSDART00000146350
fatty acyl CoA reductase 1
chr15_-_1484795 1.25 ENSDART00000129356
si:dkeyp-97b10.3
chr5_+_20030414 1.24 ENSDART00000181430
ENSDART00000047841
ENSDART00000182813
small G protein signaling modulator 1a
chr2_-_37353098 1.24 ENSDART00000056522
SKI-like proto-oncogene a
chr13_+_25364324 1.23 ENSDART00000187471
conserved helix-loop-helix ubiquitous kinase
chr4_+_40018440 1.23 ENSDART00000110827
si:dkey-199k11.6
chr16_+_26601364 1.22 ENSDART00000087537
erythrocyte membrane protein band 4.1 like 4B
chr6_-_1566186 1.22 ENSDART00000156305
tripartite motif containing 107
chr6_+_58280936 1.22 ENSDART00000155244
Ral GTPase activating protein, beta subunit (non-catalytic)
chr17_-_2039511 1.22 ENSDART00000160223
serine peptidase inhibitor, Kunitz type 1 a
chr20_+_1316495 1.21 ENSDART00000064439
nucleoporin 43
chr22_+_18319666 1.19 ENSDART00000033103
GATA zinc finger domain containing 2Ab
chr21_+_19319804 1.19 ENSDART00000063621
abraxas 2a, BRISC complex subunit
chr14_+_15768942 1.17 ENSDART00000158998
endoplasmic reticulum-golgi intermediate compartment 1
chr4_-_20222182 1.16 ENSDART00000132464
gamma-secretase activating protein
chr6_+_44163727 1.13 ENSDART00000064878
glucoside xylosyltransferase 2
chr18_+_2153530 1.13 ENSDART00000158255
pygopus family PHD finger 1
chr12_-_28349026 1.13 ENSDART00000183768
ENSDART00000152998
zgc:195081
chr2_+_38025260 1.12 ENSDART00000075905
heterogeneous nuclear ribonucleoprotein C
chr6_+_49771626 1.12 ENSDART00000134207
cathepsin Z
chr19_-_10214264 1.10 ENSDART00000053300
ENSDART00000148225
zinc finger protein 865
chr6_+_48348415 1.09 ENSDART00000064826
Mov10 RISC complex RNA helicase a
chr20_-_6476705 1.08 ENSDART00000077095
trafficking protein particle complex 8
chr12_-_41759686 1.06 ENSDART00000172175
ENSDART00000165152
protein phosphatase 2, regulatory subunit B, delta
chr6_-_9646275 1.06 ENSDART00000012903
WD repeat domain 12
chr20_+_27087539 1.06 ENSDART00000062094
transmembrane protein 251
chr11_-_34151487 1.05 ENSDART00000173039
ATPase 13A3
chr14_+_22076596 1.04 ENSDART00000106147
ENSDART00000100278
ENSDART00000131489
solute carrier family 43 (amino acid system L transporter), member 1a
chr25_+_8447565 1.03 ENSDART00000142090
Fanconi anemia, complementation group I
chr7_-_6441865 1.02 ENSDART00000172831
histone cluster 1 H2A family member 10
chr23_-_29553691 1.01 ENSDART00000053804
ubiquitination factor E4B, UFD2 homolog (S. cerevisiae)
chr19_-_29303788 1.00 ENSDART00000112167
serum response factor binding protein 1
chr12_-_3077395 0.98 ENSDART00000002867
ENSDART00000126315
RFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase
chr22_-_4439311 0.97 ENSDART00000169317
ubiquitin-like with PHD and ring finger domains 1
chr12_-_16452200 0.96 ENSDART00000037601
ribonuclease P/MRP 30 subunit
chr13_+_24263049 0.96 ENSDART00000135992
ENSDART00000088005
ATP-binding cassette, sub-family B (MDR/TAP), member 10
chr12_-_24060358 0.95 ENSDART00000050831
ChaC, cation transport regulator homolog 2 (E. coli)
chr2_+_34967210 0.95 ENSDART00000141796
astrotactin 1
chr21_+_17301790 0.95 ENSDART00000145057
TSC complex subunit 1b
chr10_+_7719796 0.95 ENSDART00000191795
gamma-glutamyl carboxylase
chr1_-_29747702 0.95 ENSDART00000133225
ENSDART00000189670
secreted phosphoprotein 2
chr22_-_6499055 0.92 ENSDART00000142235
ENSDART00000183588
si:dkey-19a16.7
chr9_-_23765480 0.91 ENSDART00000027212
si:ch211-219a4.6
chr6_-_10728057 0.90 ENSDART00000002247
Sp3b transcription factor
chr23_+_31000243 0.89 ENSDART00000085263
selenoprotein I
chr8_+_18545933 0.89 ENSDART00000148806
TGF-beta activated kinase 1/MAP3K7 binding protein 3
chr11_+_2855430 0.88 ENSDART00000172837
kinesin family member 21B
chr22_+_18319230 0.88 ENSDART00000184747
ENSDART00000184649
GATA zinc finger domain containing 2Ab
chr7_-_20103384 0.87 ENSDART00000052902
ArfGAP with coiled-coil, ankyrin repeat and PH domains 1
chr9_-_55772937 0.87 ENSDART00000159192
A kinase (PRKA) anchor protein 17A
chr6_+_11250316 0.86 ENSDART00000137122
ATG9 autophagy related 9 homolog A (S. cerevisiae)
chr3_-_55650771 0.86 ENSDART00000162413
axin 2 (conductin, axil)
chr7_+_54222156 0.85 ENSDART00000165201
ENSDART00000158518
protein kinase C and casein kinase substrate in neurons 3
chr1_-_1885516 0.84 ENSDART00000122187
ENSDART00000131675
si:ch211-132g1.3
chr6_-_33916756 0.84 ENSDART00000137447
ENSDART00000138488
nuclear autoantigenic sperm protein (histone-binding)
chr15_+_714203 0.84 ENSDART00000153847
si:dkey-7i4.24
chr1_+_38153944 0.84 ENSDART00000135666
UDP-N-acetyl-alpha-D-galactosamine: polypeptide N-acetylgalactosaminyltransferase 7
chr6_-_23002373 0.83 ENSDART00000037709
ENSDART00000170369
nucleolar protein 11
chr25_+_27410352 0.83 ENSDART00000154362
protection of telomeres 1 homolog
chr6_+_49771372 0.82 ENSDART00000063251
cathepsin Z
chr8_+_18545539 0.81 ENSDART00000089274
TGF-beta activated kinase 1/MAP3K7 binding protein 3
chr17_+_52300018 0.81 ENSDART00000190302
estrogen-related receptor beta
chr15_+_1534644 0.80 ENSDART00000130413
structural maintenance of chromosomes 4
chr22_+_336256 0.80 ENSDART00000019155
B-cell translocation gene 2
chr7_+_32693890 0.80 ENSDART00000121972
solute carrier family 39 (zinc transporter), member 13
chr8_+_31008287 0.80 ENSDART00000129882
ENSDART00000180694
prostaglandin E synthase 2-like
chr3_-_55650417 0.79 ENSDART00000171441
axin 2 (conductin, axil)
chr14_-_49992709 0.78 ENSDART00000159988
family with sequence similarity 193, member B
chr3_+_15773991 0.77 ENSDART00000089923
zinc finger protein 652
chr23_-_35396845 0.76 ENSDART00000142038
ENSDART00000049373
ENSDART00000181978
ENSDART00000171357
cap methyltransferase 1
chr7_+_38808027 0.75 ENSDART00000052323
harbinger transposase derived 1
chr16_-_32303835 0.75 ENSDART00000191408
MMS22-like, DNA repair protein
chr6_-_45869127 0.75 ENSDART00000062459
ENSDART00000180563
RNA binding motif protein 19
chr22_-_11648094 0.73 ENSDART00000191791
dipeptidyl-peptidase 4
chr21_-_30273418 0.72 ENSDART00000187069
ENSDART00000181492
zgc:175066
chr8_+_20157798 0.71 ENSDART00000124809
acyl-CoA synthetase bubblegum family member 2
chr8_+_23802384 0.71 ENSDART00000137820
si:ch211-163l21.8
chr16_+_35595312 0.71 ENSDART00000170438
si:ch211-1i11.3
chr21_+_33187992 0.71 ENSDART00000162745
ENSDART00000188388

chr20_+_3916406 0.71 ENSDART00000064365
si:ch73-111k22.2
chr14_+_16345003 0.70 ENSDART00000003040
ENSDART00000165193
intelectin 3
chr5_+_44805269 0.69 ENSDART00000136965
cathepsin La
chr5_-_13086616 0.68 ENSDART00000051664
yippee-like 1
chr21_-_13055195 0.67 ENSDART00000133517
myogenesis regulating glycosidase (putative)
chr5_-_37820878 0.67 ENSDART00000165513
Danio rerio uncharacterized LOC567472 (LOC567472), mRNA.
chr7_-_6444011 0.67 ENSDART00000173010
zgc:112234
chr3_-_23596809 0.67 ENSDART00000156897
ubiquitin-conjugating enzyme E2Z
chr23_-_12906228 0.67 ENSDART00000138807
necdin-like 2
chr11_-_20071642 0.67 ENSDART00000162931
ENSDART00000159928
ENSDART00000191443
ENSDART00000121722
si:dkey-274m17.3
chr24_-_10828560 0.66 ENSDART00000132282
family with sequence similarity 49, member Bb
chr9_-_28274932 0.65 ENSDART00000137582
ENSDART00000146932
cAMP responsive element binding protein 1b
chr18_+_45708744 0.65 ENSDART00000077341
DEP domain containing 7
chr9_+_23003208 0.64 ENSDART00000021060
ELL associated factor 2
chr10_-_2971407 0.62 ENSDART00000132526
MARVEL domain containing 2a
chr7_-_20865005 0.61 ENSDART00000190752
fission, mitochondrial 1
chr24_+_8904741 0.60 ENSDART00000140924
guanine nucleotide binding protein (G protein), alpha activating activity polypeptide, olfactory type
chr4_-_20108833 0.59 ENSDART00000100867
family with sequence similarity 3, member C
chr4_-_17669881 0.59 ENSDART00000066997
DNA-damage regulated autophagy modulator 1
chr2_+_10007113 0.58 ENSDART00000155213
solute carrier family 35 (UDP-N-acetylglucosamine (UDP-GlcNAc) transporter), member A3b
chr7_+_8670398 0.57 ENSDART00000164195
si:ch211-1o7.2
chr5_+_36895860 0.56 ENSDART00000134493
serine/arginine-rich splicing factor 7a
chr24_+_37688729 0.55 ENSDART00000137017
H3 histone, family 3D
chr11_-_3381343 0.55 ENSDART00000002545
microspherule protein 1
chr12_-_27242498 0.55 ENSDART00000152609
ENSDART00000152170
si:dkey-11c5.11
chr14_-_31060082 0.53 ENSDART00000111601
ENSDART00000161113
muscleblind-like splicing regulator 3

Network of associatons between targets according to the STRING database.

First level regulatory network of irf5

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
1.8 5.3 GO:0010633 negative regulation of epithelial cell migration(GO:0010633)
0.6 1.7 GO:0015712 hexose phosphate transport(GO:0015712) glucose-6-phosphate transport(GO:0015760)
0.4 0.4 GO:0008584 male gonad development(GO:0008584)
0.4 1.9 GO:0030576 nuclear body organization(GO:0030575) Cajal body organization(GO:0030576)
0.4 3.6 GO:0070475 rRNA base methylation(GO:0070475)
0.4 2.5 GO:0070584 mitochondrion morphogenesis(GO:0070584)
0.3 1.3 GO:0036149 phosphatidylinositol acyl-chain remodeling(GO:0036149)
0.3 1.5 GO:0055071 manganese ion homeostasis(GO:0055071)
0.3 1.7 GO:0031116 positive regulation of microtubule polymerization(GO:0031116)
0.3 0.8 GO:1901836 regulation of transcription of nuclear large rRNA transcript from RNA polymerase I promoter(GO:1901836)
0.3 1.3 GO:0006370 7-methylguanosine mRNA capping(GO:0006370)
0.2 1.5 GO:0060876 semicircular canal formation(GO:0060876)
0.2 1.2 GO:0007252 I-kappaB phosphorylation(GO:0007252)
0.2 0.8 GO:0006335 DNA replication-dependent nucleosome assembly(GO:0006335) DNA replication-dependent nucleosome organization(GO:0034723)
0.2 1.8 GO:0030104 water homeostasis(GO:0030104)
0.2 1.1 GO:0030242 pexophagy(GO:0030242)
0.2 2.8 GO:2000369 regulation of clathrin-mediated endocytosis(GO:2000369)
0.2 1.1 GO:0016266 O-glycan processing(GO:0016266)
0.2 1.0 GO:0017187 peptidyl-glutamic acid carboxylation(GO:0017187) protein carboxylation(GO:0018214)
0.2 2.2 GO:0034311 diol metabolic process(GO:0034311)
0.2 0.6 GO:0035522 monoubiquitinated protein deubiquitination(GO:0035520) monoubiquitinated histone deubiquitination(GO:0035521) monoubiquitinated histone H2A deubiquitination(GO:0035522)
0.1 2.4 GO:0045743 positive regulation of fibroblast growth factor receptor signaling pathway(GO:0045743)
0.1 1.2 GO:0006751 glutathione catabolic process(GO:0006751)
0.1 2.8 GO:0098703 calcium ion import across plasma membrane(GO:0098703) calcium ion import into cell(GO:1990035)
0.1 0.8 GO:2000279 negative regulation of DNA biosynthetic process(GO:2000279)
0.1 1.4 GO:0010890 positive regulation of sequestering of triglyceride(GO:0010890)
0.1 1.9 GO:0007530 sex determination(GO:0007530) female gonad development(GO:0008585)
0.1 2.3 GO:0007158 neuron cell-cell adhesion(GO:0007158)
0.1 1.3 GO:0090162 establishment of epithelial cell polarity(GO:0090162)
0.1 1.2 GO:0042987 beta-amyloid formation(GO:0034205) amyloid precursor protein catabolic process(GO:0042987)
0.1 0.8 GO:0043653 mitochondrial fragmentation involved in apoptotic process(GO:0043653)
0.1 1.1 GO:1905066 regulation of canonical Wnt signaling pathway involved in heart development(GO:1905066)
0.1 1.6 GO:2000054 negative regulation of Wnt signaling pathway involved in dorsal/ventral axis specification(GO:2000054)
0.1 0.6 GO:0007191 adenylate cyclase-activating dopamine receptor signaling pathway(GO:0007191)
0.1 1.0 GO:0044030 regulation of DNA methylation(GO:0044030)
0.1 1.1 GO:0070262 peptidyl-serine dephosphorylation(GO:0070262)
0.1 0.5 GO:0045124 regulation of bone resorption(GO:0045124)
0.1 1.3 GO:0006346 methylation-dependent chromatin silencing(GO:0006346) positive regulation of chromatin silencing(GO:0031937) regulation of methylation-dependent chromatin silencing(GO:0090308) positive regulation of methylation-dependent chromatin silencing(GO:0090309)
0.1 0.6 GO:0045721 negative regulation of gluconeogenesis(GO:0045721)
0.1 0.3 GO:0039529 RIG-I signaling pathway(GO:0039529) regulation of viral-induced cytoplasmic pattern recognition receptor signaling pathway(GO:0039531) regulation of RIG-I signaling pathway(GO:0039535)
0.1 1.6 GO:0007096 regulation of exit from mitosis(GO:0007096)
0.1 1.9 GO:0090557 establishment of endothelial intestinal barrier(GO:0090557)
0.1 0.8 GO:0001516 prostaglandin biosynthetic process(GO:0001516) prostanoid biosynthetic process(GO:0046457)
0.1 0.9 GO:0014028 notochord formation(GO:0014028)
0.1 0.4 GO:0010481 epidermal cell division(GO:0010481) regulation of epidermal cell division(GO:0010482)
0.1 0.7 GO:0044090 positive regulation of vacuole organization(GO:0044090)
0.1 2.7 GO:0070936 protein K48-linked ubiquitination(GO:0070936)
0.1 0.9 GO:0006646 phosphatidylethanolamine biosynthetic process(GO:0006646)
0.1 10.8 GO:0008544 epidermis development(GO:0008544)
0.1 2.6 GO:0048920 posterior lateral line neuromast primordium migration(GO:0048920)
0.1 0.5 GO:0006012 galactose metabolic process(GO:0006012)
0.1 0.9 GO:0046849 bone remodeling(GO:0046849)
0.1 0.7 GO:0044805 late nucleophagy(GO:0044805)
0.1 1.0 GO:0046627 negative regulation of insulin receptor signaling pathway(GO:0046627) negative regulation of cellular response to insulin stimulus(GO:1900077)
0.1 1.3 GO:0006743 ubiquinone metabolic process(GO:0006743) ubiquinone biosynthetic process(GO:0006744) quinone metabolic process(GO:1901661) quinone biosynthetic process(GO:1901663)
0.1 2.1 GO:0051085 chaperone mediated protein folding requiring cofactor(GO:0051085)
0.1 1.3 GO:0043153 entrainment of circadian clock by photoperiod(GO:0043153)
0.1 2.5 GO:0035336 long-chain fatty-acyl-CoA metabolic process(GO:0035336)
0.1 3.8 GO:0071166 ribonucleoprotein complex localization(GO:0071166)
0.1 1.1 GO:0000463 maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000463)
0.1 0.8 GO:0007076 mitotic chromosome condensation(GO:0007076)
0.1 3.0 GO:0000079 regulation of cyclin-dependent protein serine/threonine kinase activity(GO:0000079) regulation of cyclin-dependent protein kinase activity(GO:1904029)
0.1 1.2 GO:0030512 negative regulation of transforming growth factor beta receptor signaling pathway(GO:0030512) negative regulation of cellular response to transforming growth factor beta stimulus(GO:1903845)
0.1 0.5 GO:0046685 response to arsenic-containing substance(GO:0046685)
0.1 0.5 GO:2000290 smoothened signaling pathway involved in ventral spinal cord patterning(GO:0021910) regulation of myotome development(GO:2000290)
0.1 1.3 GO:0007205 protein kinase C-activating G-protein coupled receptor signaling pathway(GO:0007205)
0.1 1.5 GO:0019835 cytolysis(GO:0019835)
0.1 1.8 GO:2001236 regulation of extrinsic apoptotic signaling pathway(GO:2001236)
0.1 0.1 GO:0030728 ovulation(GO:0030728)
0.1 1.0 GO:0021654 rhombomere boundary formation(GO:0021654)
0.1 1.0 GO:0090502 RNA phosphodiester bond hydrolysis, endonucleolytic(GO:0090502)
0.0 0.4 GO:1902038 positive regulation of hematopoietic stem cell differentiation(GO:1902038)
0.0 0.7 GO:0000186 activation of MAPKK activity(GO:0000186)
0.0 0.8 GO:0071577 zinc II ion transmembrane transport(GO:0071577)
0.0 2.2 GO:0000281 mitotic cytokinesis(GO:0000281)
0.0 0.2 GO:0048387 ventricular trabecula myocardium morphogenesis(GO:0003222) negative regulation of retinoic acid receptor signaling pathway(GO:0048387)
0.0 1.4 GO:0097352 autophagosome maturation(GO:0097352)
0.0 0.6 GO:0014812 muscle cell migration(GO:0014812)
0.0 0.7 GO:0042759 long-chain fatty acid biosynthetic process(GO:0042759)
0.0 1.8 GO:0030301 cholesterol transport(GO:0030301)
0.0 1.3 GO:0035845 photoreceptor cell outer segment organization(GO:0035845)
0.0 0.3 GO:0008625 extrinsic apoptotic signaling pathway via death domain receptors(GO:0008625)
0.0 0.6 GO:0015781 pyrimidine nucleotide-sugar transport(GO:0015781) pyrimidine nucleotide-sugar transmembrane transport(GO:0090481)
0.0 1.8 GO:0006367 transcription initiation from RNA polymerase II promoter(GO:0006367)
0.0 1.0 GO:0072310 glomerular visceral epithelial cell development(GO:0072015) glomerular epithelial cell development(GO:0072310)
0.0 0.7 GO:0031297 replication fork processing(GO:0031297)
0.0 2.6 GO:0002573 myeloid leukocyte differentiation(GO:0002573)
0.0 0.2 GO:0048662 regulation of smooth muscle cell proliferation(GO:0048660) negative regulation of smooth muscle cell proliferation(GO:0048662)
0.0 0.3 GO:0006566 threonine metabolic process(GO:0006566) threonine catabolic process(GO:0006567)
0.0 1.9 GO:0043044 ATP-dependent chromatin remodeling(GO:0043044)
0.0 2.3 GO:0001894 tissue homeostasis(GO:0001894)
0.0 1.7 GO:0043123 positive regulation of I-kappaB kinase/NF-kappaB signaling(GO:0043123)
0.0 2.3 GO:0030433 ER-associated ubiquitin-dependent protein catabolic process(GO:0030433)
0.0 0.4 GO:0035970 peptidyl-threonine dephosphorylation(GO:0035970)
0.0 0.2 GO:0035735 intraciliary transport involved in cilium morphogenesis(GO:0035735)
0.0 0.2 GO:0060971 embryonic heart tube left/right pattern formation(GO:0060971)
0.0 1.2 GO:0006890 retrograde vesicle-mediated transport, Golgi to ER(GO:0006890)
0.0 0.7 GO:0050870 positive regulation of homotypic cell-cell adhesion(GO:0034112) positive regulation of T cell activation(GO:0050870) positive regulation of leukocyte cell-cell adhesion(GO:1903039)
0.0 0.1 GO:0071361 cellular response to ethanol(GO:0071361)
0.0 0.1 GO:2000051 negative regulation of non-canonical Wnt signaling pathway(GO:2000051)
0.0 1.0 GO:0030490 maturation of SSU-rRNA(GO:0030490)
0.0 2.0 GO:0048015 phosphatidylinositol-mediated signaling(GO:0048015)
0.0 1.6 GO:0007492 endoderm development(GO:0007492)
0.0 1.6 GO:0007528 neuromuscular junction development(GO:0007528)
0.0 0.4 GO:0043162 ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway(GO:0043162)
0.0 2.5 GO:0090630 activation of GTPase activity(GO:0090630)
0.0 0.3 GO:0003374 dynamin polymerization involved in membrane fission(GO:0003373) dynamin polymerization involved in mitochondrial fission(GO:0003374) postsynaptic neurotransmitter receptor internalization(GO:0098884)
0.0 0.4 GO:0051092 positive regulation of NF-kappaB transcription factor activity(GO:0051092)
0.0 1.0 GO:0006342 chromatin silencing(GO:0006342)
0.0 1.2 GO:0090263 positive regulation of canonical Wnt signaling pathway(GO:0090263)
0.0 0.3 GO:0042476 odontogenesis(GO:0042476)
0.0 0.2 GO:0048096 chromatin-mediated maintenance of transcription(GO:0048096)
0.0 0.4 GO:0060059 embryonic retina morphogenesis in camera-type eye(GO:0060059)
0.0 0.5 GO:0070972 protein localization to endoplasmic reticulum(GO:0070972)
0.0 0.1 GO:0015961 diadenosine polyphosphate metabolic process(GO:0015959) diadenosine polyphosphate catabolic process(GO:0015961)
0.0 1.4 GO:0006413 translational initiation(GO:0006413)
0.0 0.2 GO:0051382 kinetochore assembly(GO:0051382) negative regulation of cysteine-type endopeptidase activity(GO:2000117)
0.0 0.2 GO:0032483 regulation of Rab protein signal transduction(GO:0032483)
0.0 1.3 GO:0016579 protein deubiquitination(GO:0016579)
0.0 0.4 GO:0032543 mitochondrial translation(GO:0032543)
0.0 0.6 GO:0007605 sensory perception of sound(GO:0007605)
0.0 1.8 GO:0045786 negative regulation of cell cycle(GO:0045786)
0.0 1.0 GO:0019722 calcium-mediated signaling(GO:0019722)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.8 3.0 GO:0097134 cyclin E1-CDK2 complex(GO:0097134)
0.4 1.1 GO:1990072 TRAPPIII protein complex(GO:1990072)
0.4 1.1 GO:0070545 PeBoW complex(GO:0070545)
0.3 2.5 GO:0042645 nucleoid(GO:0009295) mitochondrial nucleoid(GO:0042645)
0.3 1.9 GO:0005845 mRNA cap binding complex(GO:0005845)
0.2 1.0 GO:0005655 nucleolar ribonuclease P complex(GO:0005655)
0.2 2.6 GO:0031080 nuclear pore outer ring(GO:0031080)
0.2 1.8 GO:0044232 organelle membrane contact site(GO:0044232)
0.2 1.2 GO:0008385 IkappaB kinase complex(GO:0008385)
0.2 1.0 GO:0033596 TSC1-TSC2 complex(GO:0033596)
0.2 1.3 GO:0000347 THO complex(GO:0000347) THO complex part of transcription export complex(GO:0000445)
0.2 1.9 GO:0031010 ISWI-type complex(GO:0031010)
0.2 0.6 GO:0061689 tricellular tight junction(GO:0061689)
0.1 0.7 GO:0031258 lamellipodium membrane(GO:0031258)
0.1 2.3 GO:0030057 desmosome(GO:0030057)
0.1 2.1 GO:0090545 NuRD complex(GO:0016581) CHD-type complex(GO:0090545)
0.1 1.9 GO:0015030 Cajal body(GO:0015030)
0.1 2.3 GO:0046540 U4/U6 x U5 tri-snRNP complex(GO:0046540)
0.1 1.5 GO:0005579 membrane attack complex(GO:0005579)
0.1 1.8 GO:0005669 transcription factor TFIID complex(GO:0005669)
0.1 0.6 GO:0035517 PR-DUB complex(GO:0035517)
0.1 0.6 GO:0032783 ELL-EAF complex(GO:0032783)
0.1 3.5 GO:0005637 nuclear inner membrane(GO:0005637)
0.1 0.6 GO:0031231 integral component of peroxisomal membrane(GO:0005779) intrinsic component of peroxisomal membrane(GO:0031231)
0.1 0.2 GO:0008622 epsilon DNA polymerase complex(GO:0008622)
0.1 1.1 GO:0044545 NSL complex(GO:0044545)
0.1 8.5 GO:0070160 bicellular tight junction(GO:0005923) occluding junction(GO:0070160)
0.1 0.7 GO:0035101 FACT complex(GO:0035101)
0.1 1.7 GO:0035371 microtubule plus-end(GO:0035371)
0.1 1.0 GO:0000792 heterochromatin(GO:0000792)
0.1 2.1 GO:0000421 autophagosome membrane(GO:0000421)
0.1 1.8 GO:0005778 peroxisomal membrane(GO:0005778) microbody membrane(GO:0031903)
0.0 0.4 GO:0032021 NELF complex(GO:0032021)
0.0 1.2 GO:0033116 endoplasmic reticulum-Golgi intermediate compartment membrane(GO:0033116)
0.0 2.2 GO:0030496 midbody(GO:0030496)
0.0 0.8 GO:0098844 postsynaptic endocytic zone membrane(GO:0098844)
0.0 1.0 GO:0030686 90S preribosome(GO:0030686)
0.0 1.1 GO:0000159 protein phosphatase type 2A complex(GO:0000159)
0.0 0.5 GO:0043296 apical junction complex(GO:0043296)
0.0 0.1 GO:0001405 presequence translocase-associated import motor(GO:0001405)
0.0 2.8 GO:0042383 sarcolemma(GO:0042383)
0.0 0.2 GO:0031597 cytosolic proteasome complex(GO:0031597)
0.0 0.6 GO:0000783 telomere cap complex(GO:0000782) nuclear telomere cap complex(GO:0000783) nuclear chromosome, telomeric region(GO:0000784)
0.0 2.3 GO:0048786 presynaptic active zone(GO:0048786)
0.0 3.4 GO:0005802 trans-Golgi network(GO:0005802)
0.0 1.6 GO:0030173 integral component of Golgi membrane(GO:0030173) intrinsic component of Golgi membrane(GO:0031228)
0.0 1.4 GO:0005811 lipid particle(GO:0005811)
0.0 0.3 GO:1990589 ATF4-CREB1 transcription factor complex(GO:1990589)
0.0 0.4 GO:0000813 ESCRT I complex(GO:0000813)
0.0 0.5 GO:0005689 U12-type spliceosomal complex(GO:0005689)
0.0 0.2 GO:0034451 acrosomal vesicle(GO:0001669) centriolar satellite(GO:0034451)
0.0 0.2 GO:0031306 intrinsic component of mitochondrial outer membrane(GO:0031306)
0.0 0.9 GO:0005834 heterotrimeric G-protein complex(GO:0005834)
0.0 0.1 GO:0071439 clathrin complex(GO:0071439)
0.0 0.1 GO:0097648 G-protein coupled receptor dimeric complex(GO:0038037) G-protein coupled receptor heterodimeric complex(GO:0038039) G-protein coupled receptor complex(GO:0097648)
0.0 1.3 GO:0030027 lamellipodium(GO:0030027)
0.0 1.3 GO:0016607 nuclear speck(GO:0016607)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.8 2.3 GO:0016436 rRNA (uridine) methyltransferase activity(GO:0016436)
0.6 1.7 GO:0015526 hexose phosphate transmembrane transporter activity(GO:0015119) organophosphate:inorganic phosphate antiporter activity(GO:0015315) hexose-phosphate:inorganic phosphate antiporter activity(GO:0015526) glucose 6-phosphate:inorganic phosphate antiporter activity(GO:0061513)
0.4 3.3 GO:0072345 NAADP-sensitive calcium-release channel activity(GO:0072345)
0.4 1.9 GO:0030620 U2 snRNA binding(GO:0030620)
0.4 1.9 GO:1990756 protein binding, bridging involved in substrate recognition for ubiquitination(GO:1990756)
0.4 2.6 GO:0080019 fatty-acyl-CoA reductase (alcohol-forming) activity(GO:0080019)
0.3 2.4 GO:0070698 type I activin receptor binding(GO:0070698)
0.3 2.3 GO:0017070 U6 snRNA binding(GO:0017070)
0.3 2.3 GO:0034450 ubiquitin-ubiquitin ligase activity(GO:0034450)
0.3 1.2 GO:0008384 IkappaB kinase activity(GO:0008384)
0.3 1.4 GO:0004185 serine-type carboxypeptidase activity(GO:0004185)
0.3 1.1 GO:0002151 G-quadruplex RNA binding(GO:0002151)
0.3 1.0 GO:0070182 DNA polymerase binding(GO:0070182)
0.3 1.5 GO:0005384 manganese ion transmembrane transporter activity(GO:0005384)
0.2 1.0 GO:0033829 O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase activity(GO:0033829)
0.2 1.0 GO:0003839 gamma-glutamylcyclotransferase activity(GO:0003839)
0.2 1.0 GO:0008488 gamma-glutamyl carboxylase activity(GO:0008488)
0.2 2.8 GO:0035612 AP-2 adaptor complex binding(GO:0035612)
0.2 2.8 GO:0005432 calcium:sodium antiporter activity(GO:0005432)
0.2 0.8 GO:0010521 telomerase inhibitor activity(GO:0010521)
0.2 0.8 GO:0050220 prostaglandin-E synthase activity(GO:0050220)
0.2 1.5 GO:0001222 transcription corepressor binding(GO:0001222)
0.2 1.3 GO:0008526 phosphatidylinositol transporter activity(GO:0008526)
0.2 0.9 GO:0004307 ethanolaminephosphotransferase activity(GO:0004307)
0.2 1.1 GO:0035252 UDP-xylosyltransferase activity(GO:0035252)
0.1 1.3 GO:0046974 histone methyltransferase activity (H3-K9 specific)(GO:0046974)
0.1 1.3 GO:0048039 ubiquinone binding(GO:0048039)
0.1 2.1 GO:0030544 Hsp70 protein binding(GO:0030544)
0.1 0.5 GO:0033149 FFAT motif binding(GO:0033149)
0.1 0.5 GO:0030626 U12 snRNA binding(GO:0030626)
0.1 1.9 GO:0000340 RNA 7-methylguanosine cap binding(GO:0000340)
0.1 0.8 GO:0008174 mRNA methyltransferase activity(GO:0008174)
0.1 0.6 GO:0070016 armadillo repeat domain binding(GO:0070016)
0.1 0.5 GO:0098518 polynucleotide phosphatase activity(GO:0098518)
0.1 0.5 GO:0016886 ligase activity, forming phosphoric ester bonds(GO:0016886)
0.1 1.8 GO:0016251 obsolete general RNA polymerase II transcription factor activity(GO:0016251)
0.1 1.0 GO:0004526 ribonuclease P activity(GO:0004526)
0.1 1.4 GO:0002039 p53 binding(GO:0002039)
0.1 0.4 GO:0043024 ribosomal small subunit binding(GO:0043024)
0.1 0.3 GO:0016453 C-acetyltransferase activity(GO:0016453)
0.1 3.4 GO:0003950 NAD+ ADP-ribosyltransferase activity(GO:0003950)
0.1 0.3 GO:0042288 MHC class I protein binding(GO:0042288)
0.1 0.6 GO:0005459 UDP-galactose transmembrane transporter activity(GO:0005459)
0.1 0.3 GO:0035613 RNA stem-loop binding(GO:0035613)
0.1 0.7 GO:0016405 CoA-ligase activity(GO:0016405)
0.1 2.0 GO:0004435 phosphatidylinositol phospholipase C activity(GO:0004435) phospholipase C activity(GO:0004629)
0.1 1.3 GO:0004143 diacylglycerol kinase activity(GO:0004143)
0.1 1.4 GO:0004089 carbonate dehydratase activity(GO:0004089)
0.0 1.7 GO:0051010 microtubule plus-end binding(GO:0051010)
0.0 3.0 GO:0016538 cyclin-dependent protein serine/threonine kinase regulator activity(GO:0016538)
0.0 10.2 GO:0004252 serine-type endopeptidase activity(GO:0004252)
0.0 2.3 GO:0003725 double-stranded RNA binding(GO:0003725)
0.0 1.8 GO:0008013 beta-catenin binding(GO:0008013)
0.0 0.2 GO:0000048 peptidyltransferase activity(GO:0000048) glutathione hydrolase activity(GO:0036374)
0.0 0.6 GO:0035497 cAMP response element binding(GO:0035497)
0.0 1.8 GO:0015485 cholesterol binding(GO:0015485)
0.0 0.8 GO:0005385 zinc ion transmembrane transporter activity(GO:0005385)
0.0 0.7 GO:0004709 MAP kinase kinase kinase activity(GO:0004709)
0.0 0.7 GO:0070492 oligosaccharide binding(GO:0070492)
0.0 0.2 GO:0043515 kinetochore binding(GO:0043515)
0.0 0.3 GO:0008568 microtubule-severing ATPase activity(GO:0008568)
0.0 0.4 GO:0008330 protein tyrosine/threonine phosphatase activity(GO:0008330)
0.0 1.3 GO:0003707 steroid hormone receptor activity(GO:0003707)
0.0 0.5 GO:0008449 N-acetylglucosamine-6-sulfatase activity(GO:0008449)
0.0 1.0 GO:0035064 methylated histone binding(GO:0035064)
0.0 0.1 GO:0004694 eukaryotic translation initiation factor 2alpha kinase activity(GO:0004694)
0.0 1.2 GO:0061631 ubiquitin conjugating enzyme activity(GO:0061631)
0.0 2.0 GO:0004722 protein serine/threonine phosphatase activity(GO:0004722)
0.0 0.3 GO:0031682 G-protein gamma-subunit binding(GO:0031682)
0.0 0.6 GO:0031683 G-protein beta/gamma-subunit complex binding(GO:0031683)
0.0 1.4 GO:0005484 SNAP receptor activity(GO:0005484)
0.0 1.1 GO:0043021 ribonucleoprotein complex binding(GO:0043021)
0.0 3.5 GO:0050839 cell adhesion molecule binding(GO:0050839)
0.0 2.0 GO:0036459 thiol-dependent ubiquitin-specific protease activity(GO:0004843) thiol-dependent ubiquitinyl hydrolase activity(GO:0036459) ubiquitinyl hydrolase activity(GO:0101005)
0.0 0.1 GO:0004965 G-protein coupled GABA receptor activity(GO:0004965)
0.0 2.3 GO:0042393 histone binding(GO:0042393)
0.0 4.7 GO:0005096 GTPase activator activity(GO:0005096)
0.0 0.3 GO:0005003 ephrin receptor activity(GO:0005003)
0.0 4.3 GO:0061630 ubiquitin protein ligase activity(GO:0061630)
0.0 1.1 GO:0019888 protein phosphatase regulator activity(GO:0019888)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 3.0 SA REG CASCADE OF CYCLIN EXPR Expression of cyclins regulates progression through the cell cycle by activating cyclin-dependent kinases.
0.1 2.6 SIG REGULATION OF THE ACTIN CYTOSKELETON BY RHO GTPASES Genes related to regulation of the actin cytoskeleton
0.1 1.7 PID BETA CATENIN DEG PATHWAY Degradation of beta catenin
0.1 2.3 PID ECADHERIN KERATINOCYTE PATHWAY E-cadherin signaling in keratinocytes
0.1 1.2 PID AVB3 OPN PATHWAY Osteopontin-mediated events
0.1 0.4 SA G2 AND M PHASES Cdc25 activates the cdc2/cyclin B complex to induce the G2/M transition.
0.1 3.9 PID P73PATHWAY p73 transcription factor network
0.0 1.3 PID ILK PATHWAY Integrin-linked kinase signaling
0.0 0.6 PID LPA4 PATHWAY LPA4-mediated signaling events
0.0 2.3 PID TELOMERASE PATHWAY Regulation of Telomerase
0.0 0.9 PID ARF6 PATHWAY Arf6 signaling events
0.0 1.1 WNT SIGNALING Genes related to Wnt-mediated signal transduction
0.0 0.1 PID ANTHRAX PATHWAY Cellular roles of Anthrax toxin
0.0 1.0 PID FANCONI PATHWAY Fanconi anemia pathway
0.0 0.8 PID AURORA B PATHWAY Aurora B signaling
0.0 0.4 PID AR NONGENOMIC PATHWAY Nongenotropic Androgen signaling
0.0 0.4 PID P38 ALPHA BETA PATHWAY Regulation of p38-alpha and p38-beta
0.0 0.4 PID NFKAPPAB CANONICAL PATHWAY Canonical NF-kappaB pathway
0.0 0.7 PID P75 NTR PATHWAY p75(NTR)-mediated signaling
0.0 0.1 PID IL2 PI3K PATHWAY IL2 signaling events mediated by PI3K

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 2.6 REACTOME ACTIVATION OF RAC Genes involved in Activation of Rac
0.2 1.3 REACTOME ACYL CHAIN REMODELLING OF PG Genes involved in Acyl chain remodelling of PG
0.1 0.6 REACTOME OLFACTORY SIGNALING PATHWAY Genes involved in Olfactory Signaling Pathway
0.1 1.2 REACTOME IKK COMPLEX RECRUITMENT MEDIATED BY RIP1 Genes involved in IKK complex recruitment mediated by RIP1
0.1 1.7 REACTOME TRAF6 MEDIATED INDUCTION OF TAK1 COMPLEX Genes involved in TRAF6 mediated induction of TAK1 complex
0.1 1.4 REACTOME REVERSIBLE HYDRATION OF CARBON DIOXIDE Genes involved in Reversible Hydration of Carbon Dioxide
0.1 2.6 REACTOME PEROXISOMAL LIPID METABOLISM Genes involved in Peroxisomal lipid metabolism
0.1 3.0 REACTOME G1 S SPECIFIC TRANSCRIPTION Genes involved in G1/S-Specific Transcription
0.1 1.0 REACTOME GAMMA CARBOXYLATION TRANSPORT AND AMINO TERMINAL CLEAVAGE OF PROTEINS Genes involved in Gamma-carboxylation, transport, and amino-terminal cleavage of proteins
0.1 2.3 REACTOME ADHERENS JUNCTIONS INTERACTIONS Genes involved in Adherens junctions interactions
0.1 1.3 REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS Genes involved in Cell-extracellular matrix interactions
0.1 1.6 REACTOME FANCONI ANEMIA PATHWAY Genes involved in Fanconi Anemia pathway
0.1 2.5 REACTOME INTERFERON ALPHA BETA SIGNALING Genes involved in Interferon alpha/beta signaling
0.1 4.7 REACTOME ANTIVIRAL MECHANISM BY IFN STIMULATED GENES Genes involved in Antiviral mechanism by IFN-stimulated genes
0.1 0.7 REACTOME SYNTHESIS SECRETION AND INACTIVATION OF GLP1 Genes involved in Synthesis, Secretion, and Inactivation of Glucagon-like Peptide-1 (GLP-1)
0.1 2.2 REACTOME SPHINGOLIPID DE NOVO BIOSYNTHESIS Genes involved in Sphingolipid de novo biosynthesis
0.1 1.9 REACTOME LYSOSOME VESICLE BIOGENESIS Genes involved in Lysosome Vesicle Biogenesis
0.1 0.8 REACTOME PACKAGING OF TELOMERE ENDS Genes involved in Packaging Of Telomere Ends
0.1 1.1 REACTOME A TETRASACCHARIDE LINKER SEQUENCE IS REQUIRED FOR GAG SYNTHESIS Genes involved in A tetrasaccharide linker sequence is required for GAG synthesis
0.1 1.0 REACTOME PRE NOTCH PROCESSING IN GOLGI Genes involved in Pre-NOTCH Processing in Golgi
0.0 1.3 REACTOME EFFECTS OF PIP2 HYDROLYSIS Genes involved in Effects of PIP2 hydrolysis
0.0 0.4 REACTOME G2 M DNA DAMAGE CHECKPOINT Genes involved in G2/M DNA damage checkpoint
0.0 0.4 REACTOME MEMBRANE BINDING AND TARGETTING OF GAG PROTEINS Genes involved in Membrane binding and targetting of GAG proteins
0.0 0.7 REACTOME SIGNALING BY HIPPO Genes involved in Signaling by Hippo
0.0 0.3 REACTOME PEPTIDE HORMONE BIOSYNTHESIS Genes involved in Peptide hormone biosynthesis
0.0 0.4 REACTOME DOWNSTREAM TCR SIGNALING Genes involved in Downstream TCR signaling
0.0 1.5 REACTOME ION TRANSPORT BY P TYPE ATPASES Genes involved in Ion transport by P-type ATPases
0.0 0.5 REACTOME MRNA CAPPING Genes involved in mRNA Capping
0.0 1.3 REACTOME NUCLEAR RECEPTOR TRANSCRIPTION PATHWAY Genes involved in Nuclear Receptor transcription pathway
0.0 3.4 REACTOME MRNA SPLICING Genes involved in mRNA Splicing
0.0 1.3 REACTOME PI METABOLISM Genes involved in PI Metabolism
0.0 0.8 REACTOME O LINKED GLYCOSYLATION OF MUCINS Genes involved in O-linked glycosylation of mucins
0.0 0.3 REACTOME IMMUNOREGULATORY INTERACTIONS BETWEEN A LYMPHOID AND A NON LYMPHOID CELL Genes involved in Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
0.0 0.3 REACTOME ENDOSOMAL SORTING COMPLEX REQUIRED FOR TRANSPORT ESCRT Genes involved in Endosomal Sorting Complex Required For Transport (ESCRT)
0.0 0.1 REACTOME IL RECEPTOR SHC SIGNALING Genes involved in Interleukin receptor SHC signaling
0.0 0.3 REACTOME EGFR DOWNREGULATION Genes involved in EGFR downregulation
0.0 2.1 REACTOME ANTIGEN PROCESSING UBIQUITINATION PROTEASOME DEGRADATION Genes involved in Antigen processing: Ubiquitination & Proteasome degradation
0.0 0.2 REACTOME DEPOSITION OF NEW CENPA CONTAINING NUCLEOSOMES AT THE CENTROMERE Genes involved in Deposition of New CENPA-containing Nucleosomes at the Centromere