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PRJNA195909:zebrafish embryo and larva development

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Results for insm1a+insm1b

Z-value: 1.21

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Transcription factors associated with insm1a+insm1b

Gene Symbol Gene ID Gene Info
insm1b
ENSDARG00000053301 insulinoma-associated 1b
insm1a
ENSDARG00000091756 insulinoma-associated 1a

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
insm1adr11_v1_chr20_-_48485354_484853540.818.8e-03Click!
insm1bdr11_v1_chr17_+_41463942_414639420.722.8e-02Click!

Activity profile of insm1a+insm1b motif

Sorted Z-values of insm1a+insm1b motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr3_+_55131289 2.81 ENSDART00000111585
AL935210.1

chr3_+_55114097 2.61 ENSDART00000121686
hbbe1.1
hemoglobin beta embryonic-1.1
chr3_+_55122662 2.50 ENSDART00000128380
hbbe1.2
hemoglobin beta embryonic-1.2
chr5_+_43006422 2.08 ENSDART00000009182
aqp3a
aquaporin 3a
chr1_+_19332837 1.79 ENSDART00000078594
tyrp1b
tyrosinase-related protein 1b
chr4_-_17409533 1.76 ENSDART00000011943
pah
phenylalanine hydroxylase
chr12_-_4683325 1.70 ENSDART00000152771
si:ch211-255p10.3
si:ch211-255p10.3
chr8_-_14484599 1.55 ENSDART00000057644
lhx4
LIM homeobox 4
chr3_-_49566364 1.51 ENSDART00000161507
zgc:153426
zgc:153426
chr5_+_36932718 1.50 ENSDART00000037879
crx
cone-rod homeobox
chr5_-_51830997 1.34 ENSDART00000163616
homer1b
homer scaffolding protein 1b
chr25_-_28443607 1.28 ENSDART00000157243
ptprz1a
protein tyrosine phosphatase, receptor-type, Z polypeptide 1a
chr1_-_21599219 1.23 ENSDART00000148327
adamtsl7
ADAMTS-like 7
chr24_+_23959487 1.22 ENSDART00000080487
hgd
homogentisate 1,2-dioxygenase
chr10_+_21801030 1.21 ENSDART00000160881
ENSDART00000187969
pcdh1g30
protocadherin 1 gamma 30
chr1_-_18803919 1.19 ENSDART00000020970
pgm2
phosphoglucomutase 2
chr21_+_5800306 1.03 ENSDART00000020603
ccng2
cyclin G2
chr24_-_2917540 1.01 ENSDART00000164776
fam69c
family with sequence similarity 69, member C
chr14_+_42172677 0.97 ENSDART00000148544
pcdh18b
protocadherin 18b
chr22_-_23666504 0.96 ENSDART00000158665
cfh
complement factor H
chr9_-_42989297 0.95 ENSDART00000126871
ttn.2
titin, tandem duplicate 2
chr11_-_42099645 0.95 ENSDART00000173312
abhd6a
abhydrolase domain containing 6a
chr13_+_502230 0.94 ENSDART00000013007
degs1
delta(4)-desaturase, sphingolipid 1
chr6_+_8129543 0.93 ENSDART00000011724
klf1
Kruppel-like factor 1 (erythroid)
chr14_-_14566417 0.93 ENSDART00000159056
si:dkey-27i16.2
si:dkey-27i16.2
chr1_+_12767318 0.93 ENSDART00000162652
pcdh10a
protocadherin 10a
chr17_-_4318393 0.89 ENSDART00000167995
ENSDART00000153824
napba
N-ethylmaleimide-sensitive factor attachment protein, beta a
chr8_+_1082100 0.88 ENSDART00000149276
lzts3b
leucine zipper, putative tumor suppressor family member 3b
chr13_+_30951155 0.86 ENSDART00000057469
ENSDART00000162254
vstm4a
V-set and transmembrane domain containing 4a
chr6_-_10828880 0.86 ENSDART00000131458
ENSDART00000020261
chrna1
cholinergic receptor, nicotinic, alpha 1 (muscle)
chr6_-_8736766 0.84 ENSDART00000143956
cavin2b
caveolae associated protein 2b
chr4_-_5597802 0.82 ENSDART00000136229
vegfab
vascular endothelial growth factor Ab
chr4_+_13733838 0.77 ENSDART00000067166
ENSDART00000133157
cntn1b
contactin 1b
chr24_+_23959107 0.77 ENSDART00000180036
hgd
homogentisate 1,2-dioxygenase
chr9_-_23944470 0.74 ENSDART00000138754
col6a3
collagen, type VI, alpha 3
chr19_+_42609132 0.74 ENSDART00000010104
crtap
cartilage associated protein
chr9_+_4429593 0.73 ENSDART00000184855
FP015810.1

chr7_+_31871830 0.69 ENSDART00000139899
mybpc3
myosin binding protein C, cardiac
chr19_+_2726819 0.66 ENSDART00000187122
ENSDART00000112414
rapgef5a
Rap guanine nucleotide exchange factor (GEF) 5a
chr25_-_24046870 0.65 ENSDART00000047569
igf2b
insulin-like growth factor 2b
chr22_-_906757 0.62 ENSDART00000193182
FP016205.1

chr10_+_41549819 0.61 ENSDART00000114210
CABZ01049847.1

chr7_-_54677143 0.61 ENSDART00000163748
ccnd1
cyclin D1
chr25_+_16601839 0.58 ENSDART00000008986
atp6v1e1a
ATPase H+ transporting V1 subunit E1a
chr2_+_1202347 0.57 ENSDART00000075837
CABZ01084566.1

chr18_+_642889 0.54 ENSDART00000189007
CABZ01078320.1

chr7_-_3470451 0.54 ENSDART00000173387
si:ch211-285c6.6
si:ch211-285c6.6
chr14_-_4076480 0.54 ENSDART00000059231
enpp6
ectonucleotide pyrophosphatase/phosphodiesterase 6
chr17_-_52579709 0.52 ENSDART00000156806
rps6kl1
ribosomal protein S6 kinase-like 1
chr14_+_8174828 0.52 ENSDART00000167228
psd2
pleckstrin and Sec7 domain containing 2
chr20_+_1996202 0.52 ENSDART00000184143
CABZ01092781.1

chr15_+_1796313 0.51 ENSDART00000126253
fam124b
family with sequence similarity 124B
chr17_+_53425037 0.50 ENSDART00000154983
fabp10b
fatty acid binding protein 10b, liver basic
chr2_+_24507597 0.49 ENSDART00000133109
rps28
ribosomal protein S28
chr7_-_41489997 0.49 ENSDART00000174300
smarcd3b
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 3b
chr7_+_22585447 0.48 ENSDART00000149144
chrnb1l
cholinergic receptor, nicotinic, beta 1 (muscle) like
chr4_+_7888047 0.47 ENSDART00000104676
camk1da
calcium/calmodulin-dependent protein kinase 1Da
chr18_+_5137241 0.46 ENSDART00000159601
serpini1
serpin peptidase inhibitor, clade I (neuroserpin), member 1
chr21_+_25660613 0.45 ENSDART00000134017
si:dkey-17e16.15
si:dkey-17e16.15
chr2_+_24507770 0.45 ENSDART00000154802
ENSDART00000052063
rps28
ribosomal protein S28
chr7_+_73397283 0.44 ENSDART00000174390
CABZ01081780.1

chr10_+_14210667 0.42 ENSDART00000138854
si:dkey-286h21.1
si:dkey-286h21.1
chr21_-_43117327 0.41 ENSDART00000122352
p4ha2
procollagen-proline, 2-oxoglutarate 4-dioxygenase (proline 4-hydroxylase), alpha polypeptide 2
chr23_-_21797517 0.39 ENSDART00000110041
lrrc38a
leucine rich repeat containing 38a
chr5_-_16274058 0.38 ENSDART00000090684
kremen1
kringle containing transmembrane protein 1
chr9_+_38427572 0.37 ENSDART00000108860
CYP27A1 (1 of many)
zgc:136333
chr8_-_23765207 0.37 ENSDART00000141871
INAVA
si:ch211-163l21.4
chr21_+_11105007 0.37 ENSDART00000128859
ENSDART00000193105
prlra
prolactin receptor a
chr5_-_37252111 0.37 ENSDART00000185110
lrch2
leucine-rich repeats and calponin homology (CH) domain containing 2
chr3_+_14388010 0.34 ENSDART00000171726
ENSDART00000165452
tmem56b
transmembrane protein 56b
chr6_+_3166941 0.34 ENSDART00000168912
ptprfa
protein tyrosine phosphatase, receptor type, f, a
chr3_+_49043917 0.34 ENSDART00000158212
zgc:92161
zgc:92161
chr8_+_23521974 0.34 ENSDART00000188130
ENSDART00000129378
sema3gb
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3Gb
chr5_+_8919698 0.33 ENSDART00000046440
agpat9l
1-acylglycerol-3-phosphate O-acyltransferase 9, like
chr6_-_46875310 0.33 ENSDART00000154442
igfn1.3
immunoglobulin-like and fibronectin type III domain containing 1, tandem duplicate 3
chr13_+_23176330 0.32 ENSDART00000168351
sorbs1
sorbin and SH3 domain containing 1
chr3_-_61592417 0.31 ENSDART00000155082
nptx2a
neuronal pentraxin 2a
chr10_+_15106808 0.30 ENSDART00000141588
scpp8
secretory calcium-binding phosphoprotein 8
chr12_+_47907277 0.29 ENSDART00000097714
tbata
thymus, brain and testes associated
chr12_-_48992527 0.29 ENSDART00000169696
CDHR1 (1 of many)
cadherin related family member 1
chr14_+_14568437 0.29 ENSDART00000164749
pcdh20
protocadherin 20
chr4_+_70791887 0.28 ENSDART00000164234
si:ch211-127b6.2
si:ch211-127b6.2
chr22_-_881080 0.27 ENSDART00000185489
cept1b
choline/ethanolamine phosphotransferase 1b
chr8_-_37391372 0.26 ENSDART00000190407
ENSDART00000009569
slc12a5b
solute carrier family 12 (potassium/chloride transporter), member 5b
chr3_+_12829566 0.25 ENSDART00000157672
si:ch211-8c17.2
si:ch211-8c17.2
chr18_+_50278858 0.25 ENSDART00000014582
si:dkey-105e17.1
si:dkey-105e17.1
chr12_-_45349849 0.24 ENSDART00000183036
CABZ01068367.1
Danio rerio uncharacterized LOC100332446 (LOC100332446), mRNA.
chr20_+_1834262 0.24 ENSDART00000185316
CABZ01065423.1

chr11_-_40101246 0.23 ENSDART00000161083
tnfrsf9b
tumor necrosis factor receptor superfamily, member 9b
chr17_+_9310259 0.22 ENSDART00000186158
ENSDART00000190329
NPAS3
neuronal PAS domain protein 3
chr16_-_29458806 0.21 ENSDART00000047931
lingo4b
leucine rich repeat and Ig domain containing 4b
chr11_+_24620742 0.21 ENSDART00000182471
ENSDART00000048365
syt6b
synaptotagmin VIb
chr25_-_19661198 0.20 ENSDART00000149641
atp2b1b
ATPase plasma membrane Ca2+ transporting 1b
chr23_-_452365 0.20 ENSDART00000146776
tspan2b
tetraspanin 2b
chr10_+_20070178 0.20 ENSDART00000027612
ENSDART00000145264
ENSDART00000172713
xpo7
exportin 7
chr8_-_23684659 0.20 ENSDART00000136865
cfp
complement factor properdin
chr25_-_13659249 0.19 ENSDART00000045488
csnk2a2b
casein kinase 2, alpha prime polypeptide b
chr7_-_72423666 0.18 ENSDART00000191214
rph3ab
rabphilin 3A homolog (mouse), b
chr18_+_40552620 0.18 ENSDART00000087699
si:ch211-132b12.1
si:ch211-132b12.1
chr4_+_75458537 0.17 ENSDART00000166278
si:ch211-266c8.1
si:ch211-266c8.1
chr13_+_41819817 0.17 ENSDART00000185778
CABZ01066611.1

chr1_+_2112726 0.17 ENSDART00000131714
ENSDART00000138396
mbnl2
muscleblind-like splicing regulator 2
chr21_+_11776328 0.15 ENSDART00000134469
ENSDART00000081646
glrx
glutaredoxin (thioltransferase)
chr8_+_41453691 0.15 ENSDART00000061144
arpc5la
actin related protein 2/3 complex, subunit 5-like, a
chr21_-_35534401 0.15 ENSDART00000112308
si:dkeyp-23e4.3
si:dkeyp-23e4.3
chr12_+_4573696 0.14 ENSDART00000152534
si:dkey-94f20.4
si:dkey-94f20.4
chr5_-_30984271 0.13 ENSDART00000051392
spns3
spinster homolog 3 (Drosophila)
chr21_-_30415524 0.13 ENSDART00000101036
grpel2
GrpE-like 2, mitochondrial
chr9_+_53719230 0.13 ENSDART00000165827
PCDH8
si:ch211-199f5.1
chr5_-_10236599 0.12 ENSDART00000099834
si:ch73-42k18.1
si:ch73-42k18.1
chr11_-_26040594 0.12 ENSDART00000144115
kaznb
kazrin, periplakin interacting protein b
chr9_+_29040425 0.12 ENSDART00000150201
MRAS
si:ch73-116o1.2
chr7_-_72261721 0.12 ENSDART00000172229
RASGRP2
RAS guanyl releasing protein 2
chr16_-_31686602 0.11 ENSDART00000170357
c1s
complement component 1, s subcomponent
chr9_-_1434484 0.10 ENSDART00000093412
osbpl6
oxysterol binding protein-like 6
chr4_+_71018579 0.10 ENSDART00000186727
si:dkeyp-80d11.10
si:dkeyp-80d11.10
chr22_+_15336752 0.10 ENSDART00000139070
sult3st2
sulfotransferase family 3, cytosolic sulfotransferase 2
chr11_-_309420 0.10 ENSDART00000173185
poc1a
POC1 centriolar protein A
chr15_-_37921998 0.08 ENSDART00000193597
ENSDART00000181443
ENSDART00000168790
si:dkey-238d18.5
si:dkey-238d18.5
chr16_-_22729491 0.08 ENSDART00000189854
tlr19
toll-like receptor 19
chr16_-_10316359 0.08 ENSDART00000104025
flot1b
flotillin 1b
chr24_-_33873451 0.08 ENSDART00000159840
asic1c
acid-sensing (proton-gated) ion channel 1c
chr11_+_19060278 0.07 ENSDART00000164294
magi1b
membrane associated guanylate kinase, WW and PDZ domain containing 1b
chr21_+_40261187 0.07 ENSDART00000142204
si:ch211-218m3.11
si:ch211-218m3.11
chr4_+_42412212 0.07 ENSDART00000163299
si:dkey-16p6.1
si:dkey-16p6.1
chr6_+_9421279 0.06 ENSDART00000161036
kalrnb
kalirin RhoGEF kinase b
chr11_-_30352333 0.06 ENSDART00000030794
tmem169a
transmembrane protein 169a
chr14_-_30876299 0.05 ENSDART00000180305
ubl3b
ubiquitin-like 3b
chr2_+_7132292 0.05 ENSDART00000153404
ENSDART00000012119
zgc:110366
zgc:110366
chr8_+_8936912 0.04 ENSDART00000135958
si:dkey-83k24.5
si:dkey-83k24.5
chr13_-_50546634 0.04 ENSDART00000192127
CU570781.2

chr13_+_13668991 0.04 ENSDART00000148266
pimr48
Pim proto-oncogene, serine/threonine kinase, related 48
chr1_+_56955349 0.03 ENSDART00000152758
si:ch211-1f22.10
si:ch211-1f22.10
chr21_+_6197223 0.03 ENSDART00000147716
si:dkey-93m18.3
si:dkey-93m18.3
chr8_-_49705058 0.03 ENSDART00000083760
frmd3
FERM domain containing 3
chr15_-_33925851 0.02 ENSDART00000187807
ENSDART00000187780
mag
myelin associated glycoprotein
chr17_-_52609728 0.02 ENSDART00000103572
lrrc74a
leucine rich repeat containing 74A
chr1_+_55452892 0.01 ENSDART00000122508
CR788255.1

chr18_+_48608366 0.01 ENSDART00000151229
kcnj5
potassium inwardly-rectifying channel, subfamily J, member 5
chr1_+_55002583 0.01 ENSDART00000037250
si:ch211-196h16.12
si:ch211-196h16.12
chr10_+_22527715 0.01 ENSDART00000134864
gigyf1b
GRB10 interacting GYF protein 1b
chr16_-_54357200 0.00 ENSDART00000170753
CABZ01111454.1

chr9_-_41077934 0.00 ENSDART00000100342
ankar
ankyrin and armadillo repeat containing
chr14_+_35369979 0.00 ENSDART00000144702
ENSDART00000169712
clint1a
clathrin interactor 1a

Network of associatons between targets according to the STRING database.

First level regulatory network of insm1a+insm1b

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 1.8 GO:0097066 response to thyroid hormone(GO:0097066)
0.3 3.7 GO:1902221 L-phenylalanine metabolic process(GO:0006558) L-phenylalanine catabolic process(GO:0006559) erythrose 4-phosphate/phosphoenolpyruvate family amino acid metabolic process(GO:1902221) erythrose 4-phosphate/phosphoenolpyruvate family amino acid catabolic process(GO:1902222)
0.2 0.9 GO:0010807 regulation of synaptic vesicle priming(GO:0010807)
0.2 1.3 GO:2001256 regulation of store-operated calcium entry(GO:2001256)
0.2 0.5 GO:0019695 choline metabolic process(GO:0019695)
0.2 1.5 GO:0060573 ventral spinal cord interneuron specification(GO:0021521) cell fate specification involved in pattern specification(GO:0060573)
0.1 0.7 GO:0003210 cardiac atrium formation(GO:0003210)
0.1 2.6 GO:0015671 oxygen transport(GO:0015671)
0.1 0.6 GO:0031571 mitotic G1 DNA damage checkpoint(GO:0031571)
0.1 0.9 GO:0086009 membrane repolarization(GO:0086009)
0.1 0.4 GO:0038161 prolactin signaling pathway(GO:0038161)
0.1 1.7 GO:0006825 copper ion transport(GO:0006825)
0.1 0.4 GO:0048903 anterior lateral line neuromast hair cell differentiation(GO:0048903)
0.1 0.9 GO:0048769 sarcomerogenesis(GO:0048769)
0.1 0.9 GO:0061001 regulation of dendritic spine morphogenesis(GO:0061001)
0.1 0.6 GO:0060754 mast cell chemotaxis(GO:0002551) regulation of mast cell chemotaxis(GO:0060753) positive regulation of mast cell chemotaxis(GO:0060754) mast cell migration(GO:0097531)
0.1 1.1 GO:0019511 peptidyl-proline hydroxylation(GO:0019511)
0.1 0.5 GO:0032986 nucleosome disassembly(GO:0006337) chromatin disassembly(GO:0031498) protein-DNA complex disassembly(GO:0032986)
0.1 0.9 GO:0097324 melanocyte migration(GO:0097324)
0.0 0.9 GO:0000028 ribosomal small subunit assembly(GO:0000028)
0.0 0.1 GO:1901890 positive regulation of cell junction assembly(GO:1901890)
0.0 0.6 GO:0046626 regulation of insulin receptor signaling pathway(GO:0046626)
0.0 0.3 GO:0097374 sensory neuron axon guidance(GO:0097374)
0.0 0.3 GO:0016024 CDP-diacylglycerol biosynthetic process(GO:0016024) CDP-diacylglycerol metabolic process(GO:0046341)
0.0 1.3 GO:0035335 peptidyl-tyrosine dephosphorylation(GO:0035335)
0.0 0.9 GO:0060319 primitive erythrocyte differentiation(GO:0060319)
0.0 1.5 GO:0042462 eye photoreceptor cell development(GO:0042462)
0.0 0.3 GO:0006646 phosphatidylethanolamine biosynthetic process(GO:0006646)
0.0 1.0 GO:1904029 regulation of cyclin-dependent protein serine/threonine kinase activity(GO:0000079) regulation of cyclin-dependent protein kinase activity(GO:1904029)
0.0 1.3 GO:0030318 melanocyte differentiation(GO:0030318)
0.0 0.5 GO:0008345 larval locomotory behavior(GO:0008345) larval behavior(GO:0030537)
0.0 0.5 GO:1990798 pancreas regeneration(GO:1990798)
0.0 0.2 GO:0006611 protein export from nucleus(GO:0006611)
0.0 0.9 GO:0046513 ceramide biosynthetic process(GO:0046513)
0.0 0.1 GO:0070207 protein homotrimerization(GO:0070207)
0.0 1.0 GO:0006006 glucose metabolic process(GO:0006006)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 0.9 GO:0098556 cytoplasmic side of rough endoplasmic reticulum membrane(GO:0098556)
0.2 0.9 GO:0070044 synaptobrevin 2-SNAP-25-syntaxin-1a complex(GO:0070044)
0.2 2.6 GO:0031838 haptoglobin-hemoglobin complex(GO:0031838)
0.1 1.8 GO:0045009 melanosome membrane(GO:0033162) chitosome(GO:0045009)
0.1 1.3 GO:0005892 acetylcholine-gated channel complex(GO:0005892)
0.0 1.7 GO:0031970 mitochondrial intermembrane space(GO:0005758) organelle envelope lumen(GO:0031970)
0.0 1.6 GO:0000307 cyclin-dependent protein kinase holoenzyme complex(GO:0000307)
0.0 0.1 GO:0001405 presequence translocase-associated import motor(GO:0001405)
0.0 0.5 GO:0071564 npBAF complex(GO:0071564)
0.0 0.6 GO:0033178 proton-transporting two-sector ATPase complex, catalytic domain(GO:0033178)
0.0 0.9 GO:0005901 caveola(GO:0005901) plasma membrane raft(GO:0044853)
0.0 2.2 GO:0014069 postsynaptic density(GO:0014069)
0.0 0.2 GO:0005956 protein kinase CK2 complex(GO:0005956)
0.0 0.5 GO:0032587 ruffle membrane(GO:0032587)
0.0 0.9 GO:0005814 centriole(GO:0005814)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 2.1 GO:0015105 arsenite transmembrane transporter activity(GO:0015105)
0.3 1.7 GO:0016531 copper chaperone activity(GO:0016531)
0.3 0.9 GO:0042166 neurotransmitter binding(GO:0042165) acetylcholine binding(GO:0042166)
0.3 1.3 GO:0035256 G-protein coupled glutamate receptor binding(GO:0035256)
0.2 2.6 GO:0031720 haptoglobin binding(GO:0031720)
0.2 0.8 GO:0043183 vascular endothelial growth factor receptor 1 binding(GO:0043183)
0.2 1.8 GO:0016714 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced pteridine as one donor, and incorporation of one atom of oxygen(GO:0016714)
0.1 0.9 GO:0005483 soluble NSF attachment protein activity(GO:0005483)
0.1 1.2 GO:0016868 intramolecular transferase activity, phosphotransferases(GO:0016868)
0.1 0.4 GO:0004925 prolactin receptor activity(GO:0004925)
0.1 0.6 GO:0005159 insulin-like growth factor receptor binding(GO:0005159)
0.1 0.7 GO:0032036 myosin heavy chain binding(GO:0032036)
0.1 0.3 GO:0004142 diacylglycerol cholinephosphotransferase activity(GO:0004142) ethanolaminephosphotransferase activity(GO:0004307)
0.0 0.8 GO:0005080 protein kinase C binding(GO:0005080)
0.0 2.4 GO:0016702 oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen(GO:0016702)
0.0 0.3 GO:0004366 glycerol-3-phosphate O-acyltransferase activity(GO:0004366)
0.0 0.6 GO:0008553 hydrogen-exporting ATPase activity, phosphorylative mechanism(GO:0008553)
0.0 0.9 GO:0008307 structural constituent of muscle(GO:0008307)
0.0 1.6 GO:0016538 cyclin-dependent protein serine/threonine kinase regulator activity(GO:0016538)
0.0 0.5 GO:0022848 acetylcholine-gated cation channel activity(GO:0022848)
0.0 0.2 GO:0005049 nuclear export signal receptor activity(GO:0005049)
0.0 0.7 GO:0005518 collagen binding(GO:0005518)
0.0 0.1 GO:0044736 acid-sensing ion channel activity(GO:0044736)
0.0 0.2 GO:0005388 calcium-transporting ATPase activity(GO:0005388)
0.0 0.2 GO:0005332 gamma-aminobutyric acid:sodium symporter activity(GO:0005332)
0.0 0.1 GO:0000774 adenyl-nucleotide exchange factor activity(GO:0000774)
0.0 0.5 GO:0010857 calcium-dependent protein kinase activity(GO:0010857)
0.0 1.2 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
0.0 0.1 GO:0004032 alditol:NADP+ 1-oxidoreductase activity(GO:0004032)
0.0 0.3 GO:0015377 cation:chloride symporter activity(GO:0015377) potassium:chloride symporter activity(GO:0015379)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.6 PID P38 GAMMA DELTA PATHWAY Signaling mediated by p38-gamma and p38-delta
0.0 0.7 NABA COLLAGENS Genes encoding collagen proteins
0.0 0.9 PID ERBB2 ERBB3 PATHWAY ErbB2/ErbB3 signaling events
0.0 0.3 SIG INSULIN RECEPTOR PATHWAY IN CARDIAC MYOCYTES Genes related to the insulin receptor pathway

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 1.0 REACTOME REGULATION OF COMPLEMENT CASCADE Genes involved in Regulation of Complement cascade
0.1 0.9 REACTOME PRESYNAPTIC NICOTINIC ACETYLCHOLINE RECEPTORS Genes involved in Presynaptic nicotinic acetylcholine receptors
0.1 1.2 REACTOME GLYCOGEN BREAKDOWN GLYCOGENOLYSIS Genes involved in Glycogen breakdown (glycogenolysis)
0.0 0.9 REACTOME SPHINGOLIPID DE NOVO BIOSYNTHESIS Genes involved in Sphingolipid de novo biosynthesis
0.0 1.5 REACTOME COLLAGEN FORMATION Genes involved in Collagen formation
0.0 3.7 REACTOME METABOLISM OF AMINO ACIDS AND DERIVATIVES Genes involved in Metabolism of amino acids and derivatives
0.0 0.9 REACTOME FORMATION OF THE TERNARY COMPLEX AND SUBSEQUENTLY THE 43S COMPLEX Genes involved in Formation of the ternary complex, and subsequently, the 43S complex
0.0 0.6 REACTOME G1 PHASE Genes involved in G1 Phase
0.0 0.3 REACTOME SMOOTH MUSCLE CONTRACTION Genes involved in Smooth Muscle Contraction
0.0 0.1 REACTOME RAP1 SIGNALLING Genes involved in Rap1 signalling