Project

PRJNA195909:zebrafish embryo and larva development

Navigation
Downloads

Results for ikzf2

Z-value: 0.69

Motif logo

Transcription factors associated with ikzf2

Gene Symbol Gene ID Gene Info
ENSDARG00000069111 IKAROS family zinc finger 2

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
IKZF2dr11_v1_chr9_-_40011673_40011673-0.383.1e-01Click!

Activity profile of ikzf2 motif

Sorted Z-values of ikzf2 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr16_+_23398369 1.47 ENSDART00000037694
S100 calcium binding protein A10b
chr16_+_23397785 1.43 ENSDART00000148961
S100 calcium binding protein A10b
chr3_+_30921246 1.41 ENSDART00000076850
claudin i
chr3_+_55131289 1.07 ENSDART00000111585

chr7_-_35432901 1.00 ENSDART00000026712
matrix metallopeptidase 2
chr11_+_21910343 0.95 ENSDART00000161485
forkhead box P4
chr3_-_61203203 0.91 ENSDART00000171787
parvalbumin 1
chr3_-_20091964 0.86 ENSDART00000029386
ENSDART00000020253
ENSDART00000124326
solute carrier family 4 (anion exchanger), member 1a (Diego blood group)
chr3_-_46817838 0.82 ENSDART00000028610
ELAV like neuron-specific RNA binding protein 3
chr12_-_30844304 0.81 ENSDART00000146367
crystallin, gamma MX, like 2
chr3_-_46818001 0.81 ENSDART00000166505
ELAV like neuron-specific RNA binding protein 3
chr18_+_48428713 0.78 ENSDART00000076861
Fli-1 proto-oncogene, ETS transcription factor a
chr21_-_26495700 0.74 ENSDART00000109379
CD248 molecule, endosialin b
chr3_-_46817499 0.71 ENSDART00000013717
ELAV like neuron-specific RNA binding protein 3
chr12_-_4070058 0.70 ENSDART00000042200
aldolase a, fructose-bisphosphate, b
chr16_+_19732543 0.66 ENSDART00000149901
ENSDART00000052927
twist family bHLH transcription factor 1b
chr21_+_25187210 0.66 ENSDART00000101147
ENSDART00000167528
si:dkey-183i3.5
chr1_-_56223913 0.64 ENSDART00000019573
zgc:65894
chr13_-_16257848 0.64 ENSDART00000079745
zgc:110045
chr6_+_39360377 0.64 ENSDART00000028260
ENSDART00000151322
zgc:77517
chr3_-_61181018 0.64 ENSDART00000187970
parvalbumin 4
chr6_+_15250672 0.61 ENSDART00000155951
si:ch73-23l24.1
chr1_+_7679328 0.60 ENSDART00000163488
ENSDART00000190070
engrailed homeobox 1b
chr13_+_22264914 0.60 ENSDART00000060576
myozenin 1a
chr18_+_19648275 0.59 ENSDART00000100569
SMAD family member 6b
chr9_+_53276356 0.59 ENSDART00000003310
SRY (sex determining region Y)-box 21b
chr2_+_55984788 0.58 ENSDART00000183599
nicotinamide riboside kinase 2
chr19_+_48176745 0.57 ENSDART00000164963
PR domain containing 1b, with ZNF domain
chr6_+_29791164 0.56 ENSDART00000017424
prothymosin, alpha a
chr16_+_26774182 0.55 ENSDART00000042895
cadherin 17, LI cadherin (liver-intestine)
chr12_+_28367557 0.54 ENSDART00000066294
cyclin-dependent kinase 5, regulatory subunit 1b (p35)
chr12_+_17106117 0.53 ENSDART00000149990
actin, alpha 2, smooth muscle, aorta
chr2_-_37210397 0.52 ENSDART00000084938
apolipoprotein Da, duplicate 1
chr5_-_68916623 0.51 ENSDART00000141917
ENSDART00000109053
ankyrin 1, erythrocytic a
chr11_+_21910752 0.50 ENSDART00000114288
forkhead box P4
chr21_+_11468934 0.49 ENSDART00000126045
ENSDART00000129744
ENSDART00000102368
glutamate receptor, ionotropic, N-methyl D-aspartate 1a
chr13_+_24662238 0.49 ENSDART00000014176
muscle segment homeobox 3
chr3_+_14611299 0.48 ENSDART00000140577
tetraspanin 35
chr15_+_29088426 0.48 ENSDART00000187290
si:ch211-137a8.4
chr16_+_33655890 0.47 ENSDART00000143757
four and a half LIM domains 3a
chr12_+_42436920 0.46 ENSDART00000177303
early B cell factor 3a
chr19_+_30662529 0.46 ENSDART00000175662
family with sequence similarity 49, member A-like
chr11_-_32723851 0.46 ENSDART00000155592
protocadherin 17
chr2_+_29976419 0.46 ENSDART00000056748
engrailed homeobox 2b
chr1_-_40911332 0.46 ENSDART00000027463
H6 family homeobox 4
chr15_-_19250543 0.44 ENSDART00000092705
ENSDART00000138895
immunoglobulin superfamily, member 9Ba
chr7_+_71664624 0.44 ENSDART00000170273
elastin microfibril interfacer 2b
chr17_+_52822422 0.44 ENSDART00000158273
ENSDART00000161414
Meis homeobox 2a
chr16_-_9980402 0.44 ENSDART00000066372
inhibitor of DNA binding 4
chr9_-_22831836 0.44 ENSDART00000142585
nebulin
chr5_+_4332220 0.43 ENSDART00000051699
spermidine/spermine N1-acetyltransferase 1a, duplicate 1
chr15_-_21132480 0.43 ENSDART00000078734
ENSDART00000157481
alpha-2-macroglobulin-like
chr7_+_39386982 0.42 ENSDART00000146702
troponin I type 2b (skeletal, fast), tandem duplicate 2
chr9_-_1949915 0.42 ENSDART00000190712
homeobox D3a
chr19_+_25649626 0.42 ENSDART00000146947
tachykinin 1
chr2_+_22042745 0.41 ENSDART00000132039
thymocyte selection-associated high mobility group box
chr5_+_36932718 0.41 ENSDART00000037879
cone-rod homeobox
chr18_+_48423973 0.40 ENSDART00000184233
ENSDART00000147074
Fli-1 proto-oncogene, ETS transcription factor a
chr13_+_13693722 0.40 ENSDART00000110509
si:ch211-194c3.5
chr25_-_18470695 0.40 ENSDART00000034377
carboxypeptidase A5
chr10_-_7785930 0.39 ENSDART00000043961
ENSDART00000111058
myeloid-specific peroxidase
chr14_-_3381303 0.39 ENSDART00000171601
im:7150988
chr4_+_5249494 0.39 ENSDART00000150391
si:ch211-214j24.14
chr24_+_9744012 0.39 ENSDART00000129656
transmembrane protein 108
chr24_-_23320223 0.39 ENSDART00000135846
zinc finger homeobox 4
chr20_+_26702377 0.38 ENSDART00000077753
forkhead box C1b
chr1_+_1689775 0.38 ENSDART00000048828
ATPase Na+/K+ transporting subunit alpha 1a, tandem duplicate 4
chr4_+_7508316 0.38 ENSDART00000170924
ENSDART00000170933
ENSDART00000164985
ENSDART00000167571
ENSDART00000158843
ENSDART00000158999
troponin T2e, cardiac
chr15_+_46356879 0.38 ENSDART00000154388
wu:fb18f06
chr9_-_8454060 0.37 ENSDART00000110158
insulin receptor substrate 2b
chr7_-_40993456 0.37 ENSDART00000031700
engrailed homeobox 2a
chr5_-_13835461 0.37 ENSDART00000148297
ENSDART00000114841
adducin 2 (beta)
chr25_+_21832938 0.37 ENSDART00000148299
creatine kinase, mitochondrial 1
chr12_-_48477031 0.37 ENSDART00000105176
NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 8
chr18_+_8346920 0.37 ENSDART00000083421
carnitine palmitoyltransferase 1B (muscle)
chr4_+_9669717 0.36 ENSDART00000004604
si:dkey-153k10.9
chr10_+_21758811 0.36 ENSDART00000188827
protocadherin 1 gamma 11
chr23_-_20764227 0.36 ENSDART00000089750
zinc finger protein 362b
chr22_+_20427170 0.35 ENSDART00000136744
forkhead box Q2
chr2_-_24022085 0.35 ENSDART00000088643
ENSDART00000189822
collagen, type XV, alpha 1b
chr19_-_31522625 0.35 ENSDART00000158438
ENSDART00000035049
N-terminal EF-hand calcium binding protein 1
chr14_-_21219659 0.35 ENSDART00000089867
protein phosphatase 2, regulatory subunit B, gamma b
chr2_-_48196092 0.34 ENSDART00000139944
secondary ossification center associated regulator of chondrocyte maturation
chr2_-_22535 0.34 ENSDART00000157877

chr15_-_21165237 0.34 ENSDART00000157069
si:ch211-212c13.8
chr22_+_5106751 0.34 ENSDART00000138967
ataxia, cerebellar, Cayman type a
chr7_+_25920792 0.33 ENSDART00000026295
arrestin, beta 2b
chr24_-_26304386 0.33 ENSDART00000175416
otospiralin
chr20_-_5291012 0.33 ENSDART00000122892
cytochrome P450, family 46, subfamily A, polypeptide 1, tandem duplicate 3
chr11_+_34235372 0.33 ENSDART00000063150
family with sequence similarity 43, member A
chr8_+_18624658 0.33 ENSDART00000089141
fibronectin type III and SPRY domain containing 1
chr4_+_19535946 0.33 ENSDART00000192342
ENSDART00000183740
ENSDART00000180812
ENSDART00000180017
leucine rich repeat containing 4.1
chr5_-_48260145 0.32 ENSDART00000044083
ENSDART00000163250
ENSDART00000135911
myocyte enhancer factor 2cb
chr22_-_15602593 0.32 ENSDART00000036075
tropomyosin 4a
chr18_+_26422124 0.32 ENSDART00000060245
cathepsin H
chr13_-_31452516 0.32 ENSDART00000193268
reticulon 1a
chr14_-_43000836 0.32 ENSDART00000162714
protocadherin 10b
chr7_+_65673885 0.32 ENSDART00000169182
parvin, alpha b
chr12_+_30168342 0.32 ENSDART00000142756
actin binding LIM protein 1b
chr23_+_36087219 0.32 ENSDART00000154825
homeobox C3a
chr16_+_29492937 0.32 ENSDART00000011497
cathepsin K
chr15_+_1372343 0.31 ENSDART00000152285
schwannomin interacting protein 1
chr12_-_431249 0.31 ENSDART00000083827
heparan sulfate (glucosamine) 3-O-sulfotransferase 3-like
chr23_-_21446985 0.31 ENSDART00000044080
hairy-related 12
chr7_+_57866292 0.31 ENSDART00000138757
calcium/calmodulin-dependent protein kinase (CaM kinase) II delta 1
chr25_+_5039050 0.31 ENSDART00000154700
parvin, beta
chr5_-_68916455 0.31 ENSDART00000171465
ankyrin 1, erythrocytic a
chr25_+_3677650 0.31 ENSDART00000154348
prion protein, related sequence 3
chr4_+_21129752 0.30 ENSDART00000169764
synaptotagmin Ia
chr6_+_28124393 0.30 ENSDART00000089195
G protein-coupled receptor 17
chr9_+_5862040 0.30 ENSDART00000129117
PDZ domain containing 1
chr20_-_54208344 0.30 ENSDART00000169386
Finkel-Biskis-Reilly murine sarcoma virus (FBR-MuSV) ubiquitously expressed a
chr8_+_10304981 0.30 ENSDART00000160766
Pim-1 proto-oncogene, serine/threonine kinase
chr6_+_35362225 0.29 ENSDART00000133783
ENSDART00000102483
regulator of G protein signaling 4
chr20_+_46040666 0.29 ENSDART00000060744
si:dkey-7c18.24
chr4_+_15968483 0.29 ENSDART00000101575
si:dkey-117n7.5
chr1_+_44911405 0.29 ENSDART00000182465
wu:fc21g02
chr2_-_30693742 0.29 ENSDART00000090292
catenin (cadherin-associated protein), delta 2b
chr2_-_30055432 0.29 ENSDART00000056747
sonic hedgehog b
chr9_+_45839260 0.28 ENSDART00000114814
twist2
chr1_+_9290103 0.28 ENSDART00000055009
Unc4.1 homeobox (C. elegans)
chr9_-_12424791 0.28 ENSDART00000135447
ENSDART00000088199
zgc:162707
chr18_-_16123222 0.28 ENSDART00000061189
sarcospan (Kras oncogene-associated gene)
chr13_+_15004398 0.28 ENSDART00000057810
empty spiracles homeobox 1
chr12_+_13164706 0.27 ENSDART00000112565
progestin and adipoQ receptor family member IVb
chr12_+_24344611 0.27 ENSDART00000093094
neurexin 1a
chr8_+_1769475 0.27 ENSDART00000079073
serpin peptidase inhibitor, clade D (heparin cofactor), member 1
chr22_-_15602760 0.27 ENSDART00000009054
tropomyosin 4a
chr18_+_17663898 0.27 ENSDART00000021213
copine II
chr10_+_21737745 0.27 ENSDART00000170498
ENSDART00000167997
protocadherin 1 gamma 18
chr24_-_11821505 0.26 ENSDART00000058992
GLI family zinc finger 3
chr10_-_44341288 0.26 ENSDART00000166131
zinc finger, SWIM-type containing 6
chr23_+_36101185 0.26 ENSDART00000103139
homeobox C8a
chr19_-_26869103 0.26 ENSDART00000089699
proline-rich transmembrane protein 1
chr23_-_24146591 0.26 ENSDART00000133269
Rho guanine nucleotide exchange factor (GEF) 19
chr8_-_47785951 0.26 ENSDART00000143821
KN motif and ankyrin repeat domains 3
chr18_+_29402623 0.26 ENSDART00000014703
v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog a (paralog a)
chr3_-_28428198 0.26 ENSDART00000151546
RNA binding fox-1 homolog 1
chr4_+_4232562 0.26 ENSDART00000177529
small lysine rich protein 1
chr8_-_31062811 0.26 ENSDART00000142528
solute carrier family 20, member 1a
chr23_+_36106790 0.26 ENSDART00000128533
homeobox C3a
chr12_-_15205087 0.26 ENSDART00000010068
sulfotransferase family 1, cytosolic sulfotransferase 6
chr18_-_17485419 0.26 ENSDART00000018764
forkhead box L1
chr11_-_25418856 0.25 ENSDART00000013714
GATA binding protein 1a
chr1_-_26292897 0.25 ENSDART00000112899
ENSDART00000185410
CXXC finger 4
chr22_+_6677429 0.25 ENSDART00000147482
si:ch211-209l18.2
chr20_+_23173710 0.25 ENSDART00000074172
sarcoglycan, beta (dystrophin-associated glycoprotein)
chr2_-_31634978 0.25 ENSDART00000135668
si:ch211-106h4.9
chr3_-_30118856 0.25 ENSDART00000109953
protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 3
chr21_+_29077509 0.25 ENSDART00000128561
endothelial cell surface expressed chemotaxis and apoptosis regulator
chr14_-_21064199 0.25 ENSDART00000172099
si:dkey-74k8.3
chr23_+_25428513 0.25 ENSDART00000144554
formin-like 3
chr10_+_28587446 0.25 ENSDART00000030138
ENSDART00000137508
Cbl proto-oncogene B, E3 ubiquitin protein ligase
chr13_+_1575276 0.24 ENSDART00000165987
dystonin
chr3_+_37707432 0.24 ENSDART00000151236
mitogen-activated protein kinase kinase kinase 14a
chr10_-_36808348 0.24 ENSDART00000099320
dehydrogenase/reductase (SDR family) member 13a, tandem duplicate 1
chr18_+_7591381 0.24 ENSDART00000136313
si:dkeyp-1h4.6
chr1_-_669717 0.24 ENSDART00000160564
cysteine/tyrosine-rich 1
chr6_-_18959036 0.24 ENSDART00000185372
septin 9b
chr8_+_15239549 0.24 ENSDART00000132216
polyamine oxidase (exo-N4-amino) 1
chr21_+_26657404 0.24 ENSDART00000129035
ENSDART00000186550
peroxiredoxin 5
chr8_-_21372446 0.23 ENSDART00000061481
ENSDART00000079293
elastase 2 like
chr14_-_14566417 0.23 ENSDART00000159056
si:dkey-27i16.2
chr21_+_5800306 0.23 ENSDART00000020603
cyclin G2
chr4_-_22207873 0.23 ENSDART00000142140
protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 2
chr14_+_24277556 0.23 ENSDART00000122660
heterogeneous nuclear ribonucleoprotein A0a
chr25_-_30357027 0.23 ENSDART00000171137
protein disulfide isomerase family A, member 3
chr22_-_20011476 0.23 ENSDART00000093312
ENSDART00000093310
cugbp, Elav-like family member 5a
chr3_+_23691847 0.23 ENSDART00000078453
homeobox B7a
chr21_+_17880511 0.23 ENSDART00000080481
retinoid X receptor, alpha a
chr13_-_31647323 0.23 ENSDART00000135381
SIX homeobox 4a
chr4_+_3980247 0.23 ENSDART00000049194
G protein-coupled receptor 37b
chr21_+_11468642 0.23 ENSDART00000041869
glutamate receptor, ionotropic, N-methyl D-aspartate 1a
chr5_-_38506981 0.22 ENSDART00000097822
ATPase Na+/K+ transporting subunit beta 2b
chr12_+_18458502 0.22 ENSDART00000108745
ring finger protein 151
chr2_-_7696503 0.22 ENSDART00000169709

chr5_-_34609337 0.22 ENSDART00000145792
hexosaminidase B (beta polypeptide)
chr17_+_33340675 0.22 ENSDART00000184396
ENSDART00000077553
xanthine dehydrogenase
chr7_+_20524064 0.22 ENSDART00000052917
solute carrier family 3 (amino acid transporter heavy chain), member 2a
chr12_+_24344963 0.22 ENSDART00000191648
ENSDART00000183180
ENSDART00000088178
ENSDART00000189696
neurexin 1a
chr16_+_29492749 0.22 ENSDART00000179680
cathepsin K
chr8_-_14049404 0.21 ENSDART00000093117
ATPase plasma membrane Ca2+ transporting 3a
chr21_-_33851877 0.21 ENSDART00000136729
early B cell factor 1b
chr18_+_783936 0.21 ENSDART00000193357
ribonuclease P and MRP subunit p25, b
chr9_+_21407987 0.21 ENSDART00000145627
gap junction protein, alpha 3
chr17_-_14836320 0.21 ENSDART00000157051
nidogen 2a (osteonidogen)
chr7_+_69470442 0.21 ENSDART00000189593
GABA(A) receptor-associated protein b
chr18_+_39074139 0.21 ENSDART00000142390
guanine nucleotide binding protein (G protein), beta 5b
chr15_-_46779934 0.21 ENSDART00000085136
chloride channel 2c
chr3_-_37759373 0.21 ENSDART00000150962
si:dkey-260c8.6
chr8_+_20880848 0.21 ENSDART00000134488
ENSDART00000138605
ENSDART00000192234
si:ch73-196i15.3
chr23_+_44883805 0.21 ENSDART00000182805
si:ch73-361h17.1
chr16_-_31976269 0.21 ENSDART00000139664
serine/threonine/tyrosine kinase 1
chr14_+_33413980 0.21 ENSDART00000052780
ENSDART00000124437
ENSDART00000173327
NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 1
chr10_+_9159279 0.20 ENSDART00000064968
RasGEF domain family, member 1Bb
chr4_+_61995745 0.20 ENSDART00000171539

chr21_-_20711739 0.20 ENSDART00000190918

chr1_+_15137901 0.20 ENSDART00000111475
protocadherin 7a
chr16_-_31756859 0.20 ENSDART00000149170
ENSDART00000126617
ENSDART00000182722
protein tyrosine phosphatase, non-receptor type 6
chr19_-_27776649 0.20 ENSDART00000135348
adenylate cyclase 2b (brain)

Network of associatons between targets according to the STRING database.

First level regulatory network of ikzf2

PNG image of the network

In order to view interactive SVG image please either update your browser to latest version or install SVG plugin.


View svg image
View png image

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.5 GO:0090131 mesenchyme migration(GO:0090131)
0.1 0.4 GO:0006598 polyamine catabolic process(GO:0006598) putrescine catabolic process(GO:0009447)
0.1 0.4 GO:0010640 regulation of platelet-derived growth factor receptor signaling pathway(GO:0010640) platelet-derived growth factor receptor-alpha signaling pathway(GO:0035790) regulation of platelet-derived growth factor receptor-alpha signaling pathway(GO:2000583)
0.1 0.5 GO:0035881 amacrine cell differentiation(GO:0035881)
0.1 0.4 GO:0007217 tachykinin receptor signaling pathway(GO:0007217)
0.1 0.3 GO:1900120 regulation of cytokine activity(GO:0060300) regulation of receptor binding(GO:1900120) regulation of chemokine activity(GO:1900136)
0.1 1.0 GO:0060385 axonogenesis involved in innervation(GO:0060385)
0.1 0.4 GO:0071691 cardiac muscle thin filament assembly(GO:0071691)
0.1 0.2 GO:0006145 purine nucleobase catabolic process(GO:0006145)
0.1 0.3 GO:0030224 monocyte differentiation(GO:0030224)
0.1 0.3 GO:0051701 interaction with host(GO:0051701)
0.1 0.2 GO:1902410 mitotic cytokinetic process(GO:1902410) mitotic cleavage furrow formation(GO:1903673)
0.1 0.3 GO:0021731 trigeminal motor nucleus development(GO:0021731)
0.1 1.0 GO:0035701 hematopoietic stem cell migration(GO:0035701)
0.1 0.2 GO:0009162 deoxyribonucleoside monophosphate metabolic process(GO:0009162)
0.1 0.2 GO:0003161 cardiac conduction system development(GO:0003161)
0.1 0.3 GO:0035332 positive regulation of hippo signaling(GO:0035332)
0.1 0.2 GO:0090183 regulation of morphogenesis of a branching structure(GO:0060688) positive regulation of mesonephros development(GO:0061213) regulation of mesonephros development(GO:0061217) regulation of kidney development(GO:0090183) positive regulation of kidney development(GO:0090184) regulation of branching involved in ureteric bud morphogenesis(GO:0090189) positive regulation of branching involved in ureteric bud morphogenesis(GO:0090190) interneuron axon guidance(GO:0097376) spinal cord interneuron axon guidance(GO:0097377) dorsal spinal cord interneuron axon guidance(GO:0097378)
0.1 0.2 GO:1901533 negative regulation of hematopoietic progenitor cell differentiation(GO:1901533)
0.1 0.4 GO:0042984 amyloid precursor protein biosynthetic process(GO:0042983) regulation of amyloid precursor protein biosynthetic process(GO:0042984)
0.1 0.2 GO:0070914 UV-damage excision repair(GO:0070914)
0.0 0.2 GO:0010332 response to gamma radiation(GO:0010332) cellular response to gamma radiation(GO:0071480)
0.0 0.4 GO:0097106 postsynaptic density organization(GO:0097106)
0.0 0.2 GO:0034260 negative regulation of GTPase activity(GO:0034260)
0.0 0.3 GO:0021794 thalamus development(GO:0021794)
0.0 0.1 GO:1903251 multi-ciliated epithelial cell differentiation(GO:1903251)
0.0 0.2 GO:2001244 positive regulation of intrinsic apoptotic signaling pathway(GO:2001244)
0.0 0.2 GO:0007175 negative regulation of epidermal growth factor-activated receptor activity(GO:0007175)
0.0 0.3 GO:0060956 cardiac endothelial cell differentiation(GO:0003348) endocardial cell differentiation(GO:0060956)
0.0 0.1 GO:1901052 sarcosine metabolic process(GO:1901052)
0.0 0.4 GO:0003307 regulation of Wnt signaling pathway involved in heart development(GO:0003307)
0.0 0.7 GO:0035235 ionotropic glutamate receptor signaling pathway(GO:0035235)
0.0 0.9 GO:0015701 bicarbonate transport(GO:0015701)
0.0 0.5 GO:0030656 regulation of isoprenoid metabolic process(GO:0019747) regulation of vitamin metabolic process(GO:0030656) regulation of retinoic acid biosynthetic process(GO:1900052)
0.0 0.1 GO:0042941 D-amino acid transport(GO:0042940) D-alanine transport(GO:0042941) D-serine transport(GO:0042942)
0.0 0.3 GO:0035777 pronephric distal tubule development(GO:0035777)
0.0 0.3 GO:0070262 peptidyl-serine dephosphorylation(GO:0070262)
0.0 0.2 GO:0030326 embryonic limb morphogenesis(GO:0030326)
0.0 0.2 GO:0045110 intermediate filament bundle assembly(GO:0045110)
0.0 0.2 GO:0016539 intein-mediated protein splicing(GO:0016539) protein splicing(GO:0030908)
0.0 0.6 GO:0071436 cellular potassium ion homeostasis(GO:0030007) sodium ion export from cell(GO:0036376) sodium ion export(GO:0071436)
0.0 0.3 GO:0006797 polyphosphate metabolic process(GO:0006797) polyphosphate catabolic process(GO:0006798)
0.0 0.4 GO:2000377 regulation of reactive oxygen species metabolic process(GO:2000377)
0.0 0.3 GO:0016127 cholesterol catabolic process(GO:0006707) sterol catabolic process(GO:0016127)
0.0 0.1 GO:0032530 regulation of microvillus organization(GO:0032530) regulation of microvillus assembly(GO:0032534)
0.0 1.4 GO:0043297 apical junction assembly(GO:0043297) bicellular tight junction assembly(GO:0070830)
0.0 0.7 GO:0030388 fructose 1,6-bisphosphate metabolic process(GO:0030388)
0.0 0.1 GO:0014909 smooth muscle cell migration(GO:0014909)
0.0 0.1 GO:0033119 negative regulation of RNA splicing(GO:0033119) negative regulation of mRNA splicing, via spliceosome(GO:0048025)
0.0 0.6 GO:0030032 lamellipodium assembly(GO:0030032)
0.0 0.2 GO:0035479 angioblast cell migration from lateral mesoderm to midline(GO:0035479)
0.0 0.1 GO:0010133 proline catabolic process to glutamate(GO:0010133)
0.0 0.2 GO:0001682 tRNA 5'-leader removal(GO:0001682)
0.0 0.1 GO:0090136 epithelial cell-cell adhesion(GO:0090136)
0.0 0.5 GO:0055003 cardiac myofibril assembly(GO:0055003)
0.0 0.3 GO:0006603 phosphagen metabolic process(GO:0006599) phosphocreatine metabolic process(GO:0006603) phosphagen biosynthetic process(GO:0042396) phosphocreatine biosynthetic process(GO:0046314)
0.0 0.4 GO:0006120 mitochondrial electron transport, NADH to ubiquinone(GO:0006120)
0.0 0.4 GO:0009437 carnitine metabolic process(GO:0009437)
0.0 0.4 GO:0048791 calcium ion-regulated exocytosis of neurotransmitter(GO:0048791)
0.0 0.4 GO:0006995 cellular response to nitrogen starvation(GO:0006995) cellular response to nitrogen levels(GO:0043562)
0.0 0.4 GO:0048512 rhythmic behavior(GO:0007622) circadian behavior(GO:0048512)
0.0 0.1 GO:1990592 protein polyufmylation(GO:1990564) protein K69-linked ufmylation(GO:1990592)
0.0 0.1 GO:0060836 lymphatic endothelial cell differentiation(GO:0060836)
0.0 0.2 GO:0060142 regulation of syncytium formation by plasma membrane fusion(GO:0060142)
0.0 0.1 GO:0042543 protein N-linked glycosylation via arginine(GO:0042543)
0.0 0.5 GO:0030500 regulation of bone mineralization(GO:0030500) regulation of biomineral tissue development(GO:0070167)
0.0 0.1 GO:2000650 negative regulation of sodium ion transmembrane transporter activity(GO:2000650)
0.0 0.1 GO:2001045 negative regulation of integrin-mediated signaling pathway(GO:2001045)
0.0 0.2 GO:0043328 protein targeting to vacuole involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway(GO:0043328)
0.0 0.1 GO:0016038 absorption of visible light(GO:0016038)
0.0 0.1 GO:0071205 protein localization to juxtaparanode region of axon(GO:0071205) protein localization to axon(GO:0099612)
0.0 0.1 GO:0097272 ammonia homeostasis(GO:0097272)
0.0 0.2 GO:0042744 hydrogen peroxide catabolic process(GO:0042744)
0.0 0.1 GO:0097090 presynaptic membrane organization(GO:0097090) postsynaptic membrane assembly(GO:0097104) presynaptic membrane assembly(GO:0097105)
0.0 0.3 GO:0001843 neural tube closure(GO:0001843)
0.0 0.1 GO:0045899 regulation of RNA polymerase II transcriptional preinitiation complex assembly(GO:0045898) positive regulation of RNA polymerase II transcriptional preinitiation complex assembly(GO:0045899)
0.0 0.5 GO:0000302 response to reactive oxygen species(GO:0000302)
0.0 0.1 GO:0070973 protein localization to endoplasmic reticulum exit site(GO:0070973)
0.0 0.3 GO:0060997 dendritic spine morphogenesis(GO:0060997)
0.0 0.5 GO:0051016 barbed-end actin filament capping(GO:0051016)
0.0 0.0 GO:0030859 polarized epithelial cell differentiation(GO:0030859)
0.0 0.5 GO:0035138 pectoral fin morphogenesis(GO:0035138)
0.0 0.3 GO:0035435 phosphate ion transmembrane transport(GO:0035435)
0.0 0.4 GO:0042462 eye photoreceptor cell development(GO:0042462)
0.0 0.0 GO:0019532 oxalate transport(GO:0019532)
0.0 0.5 GO:0060219 camera-type eye photoreceptor cell differentiation(GO:0060219)
0.0 0.6 GO:0071277 cellular response to calcium ion(GO:0071277)
0.0 1.5 GO:0002088 lens development in camera-type eye(GO:0002088)
0.0 0.3 GO:0055013 cardiac muscle cell development(GO:0055013)
0.0 0.2 GO:0050728 negative regulation of inflammatory response(GO:0050728)
0.0 0.2 GO:0007195 adenylate cyclase-inhibiting dopamine receptor signaling pathway(GO:0007195)
0.0 0.4 GO:0006937 regulation of muscle contraction(GO:0006937)
0.0 0.5 GO:0003009 skeletal muscle contraction(GO:0003009)
0.0 0.1 GO:0001574 ganglioside biosynthetic process(GO:0001574)
0.0 0.5 GO:0030901 midbrain development(GO:0030901)
0.0 0.4 GO:0008286 insulin receptor signaling pathway(GO:0008286)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.5 GO:0016533 cyclin-dependent protein kinase 5 holoenzyme complex(GO:0016533)
0.1 0.3 GO:0042584 chromaffin granule membrane(GO:0042584)
0.0 0.7 GO:0017146 NMDA selective glutamate receptor complex(GO:0017146)
0.0 0.3 GO:0031045 dense core granule(GO:0031045)
0.0 0.2 GO:0031907 peroxisomal matrix(GO:0005782) microbody lumen(GO:0031907)
0.0 0.2 GO:0000110 nucleotide-excision repair factor 1 complex(GO:0000110)
0.0 0.5 GO:0005869 dynactin complex(GO:0005869)
0.0 0.2 GO:0000172 ribonuclease MRP complex(GO:0000172)
0.0 0.1 GO:0019815 B cell receptor complex(GO:0019815)
0.0 0.5 GO:0016010 dystrophin-associated glycoprotein complex(GO:0016010) glycoprotein complex(GO:0090665)
0.0 0.2 GO:0005890 sodium:potassium-exchanging ATPase complex(GO:0005890) cation-transporting ATPase complex(GO:0090533)
0.0 0.9 GO:0005861 troponin complex(GO:0005861)
0.0 0.3 GO:0005922 connexon complex(GO:0005922)
0.0 0.1 GO:0070195 growth hormone receptor complex(GO:0070195)
0.0 0.2 GO:0005952 cAMP-dependent protein kinase complex(GO:0005952)
0.0 0.3 GO:0031462 Cul2-RING ubiquitin ligase complex(GO:0031462)
0.0 0.2 GO:0014704 intercalated disc(GO:0014704)
0.0 2.7 GO:0030017 sarcomere(GO:0030017)
0.0 0.3 GO:0071144 SMAD2-SMAD3 protein complex(GO:0071144)
0.0 0.1 GO:0097225 sperm midpiece(GO:0097225)
0.0 0.1 GO:0005688 U6 snRNP(GO:0005688)
0.0 0.1 GO:0000126 transcription factor TFIIIB complex(GO:0000126)
0.0 0.6 GO:0005747 mitochondrial respiratory chain complex I(GO:0005747) NADH dehydrogenase complex(GO:0030964) respiratory chain complex I(GO:0045271)
0.0 0.5 GO:0000421 autophagosome membrane(GO:0000421)
0.0 0.6 GO:0016342 catenin complex(GO:0016342)
0.0 0.3 GO:0000159 protein phosphatase type 2A complex(GO:0000159)
0.0 0.4 GO:1902710 GABA receptor complex(GO:1902710) GABA-A receptor complex(GO:1902711)
0.0 0.1 GO:0031597 cytosolic proteasome complex(GO:0031597)
0.0 0.1 GO:0033010 paranodal junction(GO:0033010)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.7 GO:1990430 extracellular matrix protein binding(GO:1990430)
0.1 0.4 GO:0031834 neurokinin receptor binding(GO:0031834) substance P receptor binding(GO:0031835)
0.1 0.3 GO:0031701 angiotensin receptor binding(GO:0031701)
0.1 3.0 GO:0048306 calcium-dependent protein binding(GO:0048306)
0.1 0.7 GO:0004332 fructose-bisphosphate aldolase activity(GO:0004332)
0.1 0.6 GO:0050262 ribosylnicotinamide kinase activity(GO:0050262)
0.1 0.2 GO:0047690 aspartyltransferase activity(GO:0047690)
0.1 0.6 GO:0016316 phosphatidylinositol-3,4-bisphosphate 4-phosphatase activity(GO:0016316)
0.1 0.4 GO:0019809 spermidine binding(GO:0019809)
0.1 0.6 GO:0051373 telethonin binding(GO:0031433) FATZ binding(GO:0051373)
0.1 0.5 GO:0008467 [heparan sulfate]-glucosamine 3-sulfotransferase 1 activity(GO:0008467)
0.1 0.3 GO:0033781 cholesterol 24-hydroxylase activity(GO:0033781)
0.1 0.5 GO:0005113 patched binding(GO:0005113)
0.1 0.4 GO:0016416 carnitine O-palmitoyltransferase activity(GO:0004095) O-palmitoyltransferase activity(GO:0016416)
0.0 0.1 GO:0047256 beta-galactosyl-N-acetylglucosaminylgalactosylglucosyl-ceramide beta-1,3-acetylglucosaminyltransferase activity(GO:0008457) lactosylceramide 1,3-N-acetyl-beta-D-glucosaminyltransferase activity(GO:0047256)
0.0 0.2 GO:0046592 polyamine oxidase activity(GO:0046592)
0.0 0.1 GO:0004771 sterol esterase activity(GO:0004771)
0.0 0.2 GO:0055077 gap junction hemi-channel activity(GO:0055077)
0.0 0.1 GO:0031530 gonadotropin hormone-releasing hormone activity(GO:0005183) gonadotropin-releasing hormone receptor binding(GO:0031530)
0.0 0.5 GO:0061575 cyclin-dependent protein serine/threonine kinase activator activity(GO:0061575)
0.0 0.9 GO:0005452 inorganic anion exchanger activity(GO:0005452)
0.0 0.4 GO:0005391 sodium:potassium-exchanging ATPase activity(GO:0005391)
0.0 0.7 GO:0004972 NMDA glutamate receptor activity(GO:0004972)
0.0 0.1 GO:0070699 beta-1 adrenergic receptor binding(GO:0031697) type II activin receptor binding(GO:0070699)
0.0 0.4 GO:0031013 troponin C binding(GO:0030172) troponin I binding(GO:0031013)
0.0 0.2 GO:0008379 thioredoxin peroxidase activity(GO:0008379)
0.0 0.1 GO:0071568 UFM1 transferase activity(GO:0071568)
0.0 0.4 GO:0005158 insulin receptor binding(GO:0005158)
0.0 0.3 GO:0004309 exopolyphosphatase activity(GO:0004309)
0.0 0.1 GO:0004657 proline dehydrogenase activity(GO:0004657)
0.0 0.1 GO:0046997 oxidoreductase activity, acting on the CH-NH group of donors, flavin as acceptor(GO:0046997)
0.0 0.3 GO:0004062 aryl sulfotransferase activity(GO:0004062)
0.0 0.2 GO:0070180 large ribosomal subunit rRNA binding(GO:0070180)
0.0 0.1 GO:0005017 platelet-derived growth factor-activated receptor activity(GO:0005017) platelet-derived growth factor binding(GO:0048407)
0.0 0.2 GO:0030274 LIM domain binding(GO:0030274)
0.0 0.2 GO:0019215 intermediate filament binding(GO:0019215)
0.0 0.2 GO:0044323 retinoic acid-responsive element binding(GO:0044323)
0.0 0.2 GO:0004563 beta-N-acetylhexosaminidase activity(GO:0004563)
0.0 0.2 GO:0052650 NADP-retinol dehydrogenase activity(GO:0052650)
0.0 0.2 GO:0016725 oxidoreductase activity, acting on CH or CH2 groups(GO:0016725)
0.0 0.1 GO:0097643 amylin receptor activity(GO:0097643)
0.0 0.1 GO:0005502 11-cis retinal binding(GO:0005502)
0.0 0.1 GO:0047804 cysteine-S-conjugate beta-lyase activity(GO:0047804)
0.0 0.2 GO:0017070 U6 snRNA binding(GO:0017070)
0.0 0.3 GO:0016775 creatine kinase activity(GO:0004111) phosphotransferase activity, nitrogenous group as acceptor(GO:0016775)
0.0 0.2 GO:0004691 cAMP-dependent protein kinase activity(GO:0004691)
0.0 0.1 GO:0004903 growth hormone receptor activity(GO:0004903)
0.0 0.4 GO:0050811 GABA receptor binding(GO:0050811)
0.0 0.3 GO:0008327 methyl-CpG binding(GO:0008327)
0.0 0.9 GO:0042826 histone deacetylase binding(GO:0042826)
0.0 0.2 GO:0016864 protein disulfide isomerase activity(GO:0003756) intramolecular oxidoreductase activity, transposing S-S bonds(GO:0016864)
0.0 0.3 GO:0005315 inorganic phosphate transmembrane transporter activity(GO:0005315)
0.0 0.1 GO:0001665 alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase activity(GO:0001665)
0.0 0.4 GO:0050136 NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136)
0.0 0.1 GO:0004630 phospholipase D activity(GO:0004630)
0.0 0.1 GO:0000995 transcription factor activity, core RNA polymerase III binding(GO:0000995)
0.0 0.3 GO:0070411 I-SMAD binding(GO:0070411)
0.0 0.7 GO:0001786 phosphatidylserine binding(GO:0001786)
0.0 0.2 GO:0043495 protein anchor(GO:0043495)
0.0 0.4 GO:0004181 metallocarboxypeptidase activity(GO:0004181)
0.0 0.4 GO:0004016 adenylate cyclase activity(GO:0004016)
0.0 0.2 GO:0031682 G-protein gamma-subunit binding(GO:0031682)
0.0 0.1 GO:0016774 phosphotransferase activity, carboxyl group as acceptor(GO:0016774)
0.0 1.3 GO:0001227 transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001227)
0.0 0.1 GO:0008459 chondroitin 6-sulfotransferase activity(GO:0008459)
0.0 0.2 GO:0015271 outward rectifier potassium channel activity(GO:0015271)
0.0 0.7 GO:0005200 structural constituent of cytoskeleton(GO:0005200)
0.0 0.2 GO:0008266 poly(U) RNA binding(GO:0008266)
0.0 0.2 GO:0001671 ATPase activator activity(GO:0001671)
0.0 0.9 GO:0005212 structural constituent of eye lens(GO:0005212)
0.0 0.4 GO:0004890 GABA-A receptor activity(GO:0004890)
0.0 0.2 GO:0005092 GDP-dissociation inhibitor activity(GO:0005092)
0.0 1.2 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
0.0 0.1 GO:0015280 ligand-gated sodium channel activity(GO:0015280)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.1 PID SYNDECAN 2 PATHWAY Syndecan-2-mediated signaling events
0.0 0.3 PID IL5 PATHWAY IL5-mediated signaling events
0.0 0.2 PID INTEGRIN A9B1 PATHWAY Alpha9 beta1 integrin signaling events
0.0 0.1 PID VEGF VEGFR PATHWAY VEGF and VEGFR signaling network
0.0 0.2 PID HEDGEHOG 2PATHWAY Signaling events mediated by the Hedgehog family
0.0 0.1 PID VEGFR1 PATHWAY VEGFR1 specific signals
0.0 0.1 PID S1P S1P3 PATHWAY S1P3 pathway

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.0 REACTOME DEGRADATION OF THE EXTRACELLULAR MATRIX Genes involved in Degradation of the extracellular matrix
0.0 0.5 REACTOME TRAFFICKING AND PROCESSING OF ENDOSOMAL TLR Genes involved in Trafficking and processing of endosomal TLR
0.0 0.2 REACTOME PURINE CATABOLISM Genes involved in Purine catabolism
0.0 0.2 REACTOME PD1 SIGNALING Genes involved in PD-1 signaling
0.0 0.2 REACTOME TANDEM PORE DOMAIN POTASSIUM CHANNELS Genes involved in Tandem pore domain potassium channels
0.0 0.3 REACTOME EICOSANOID LIGAND BINDING RECEPTORS Genes involved in Eicosanoid ligand-binding receptors
0.0 0.2 REACTOME GAP JUNCTION TRAFFICKING Genes involved in Gap junction trafficking
0.0 0.4 REACTOME ACTIVATED AMPK STIMULATES FATTY ACID OXIDATION IN MUSCLE Genes involved in Activated AMPK stimulates fatty-acid oxidation in muscle
0.0 0.2 REACTOME HYALURONAN UPTAKE AND DEGRADATION Genes involved in Hyaluronan uptake and degradation
0.0 0.5 REACTOME SMOOTH MUSCLE CONTRACTION Genes involved in Smooth Muscle Contraction
0.0 0.2 REACTOME ACTIVATION OF CHAPERONE GENES BY ATF6 ALPHA Genes involved in Activation of Chaperone Genes by ATF6-alpha
0.0 0.3 REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS Genes involved in Cell-extracellular matrix interactions
0.0 0.2 REACTOME PRESYNAPTIC NICOTINIC ACETYLCHOLINE RECEPTORS Genes involved in Presynaptic nicotinic acetylcholine receptors
0.0 0.4 REACTOME MUSCLE CONTRACTION Genes involved in Muscle contraction
0.0 0.1 REACTOME TRANSPORT OF ORGANIC ANIONS Genes involved in Transport of organic anions
0.0 0.1 REACTOME ORGANIC CATION ANION ZWITTERION TRANSPORT Genes involved in Organic cation/anion/zwitterion transport
0.0 0.1 REACTOME CD28 DEPENDENT VAV1 PATHWAY Genes involved in CD28 dependent Vav1 pathway
0.0 0.2 REACTOME CALNEXIN CALRETICULIN CYCLE Genes involved in Calnexin/calreticulin cycle
0.0 0.1 REACTOME VEGF LIGAND RECEPTOR INTERACTIONS Genes involved in VEGF ligand-receptor interactions
0.0 0.1 REACTOME OPSINS Genes involved in Opsins
0.0 0.6 REACTOME RESPIRATORY ELECTRON TRANSPORT Genes involved in Respiratory electron transport