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PRJNA195909:zebrafish embryo and larva development
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Results for ikzf1
Z-value: 2.04
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Transcription factors associated with ikzf1
Activity-expression correlation:
| Gene | Promoter | Pearson corr. coef. | P-value | Plot |
|---|---|---|---|---|
| ikzf1 | dr11_v1_chr13_-_15982707_15982707 | 0.73 | 2.7e-02 | Click! |
| Promoter | Log-likelihood | Transcript | Gene | Gene Info |
|---|---|---|---|---|
| chr3_-_32817274 Show fit | 3.50 |
ENSDART00000142582
|
myosin light chain, phosphorylatable, fast skeletal muscle a |
|
| chr5_-_71722257 Show fit | 3.28 |
ENSDART00000013404
|
adenylate kinase 1 |
|
| chr25_+_29161609 Show fit | 3.11 |
ENSDART00000180752
|
pyruvate kinase M1/2b |
|
| chr7_-_8416750 Show fit | 2.84 |
ENSDART00000181857
|
jacalin 1 |
|
| chr11_-_21030070 Show fit | 2.77 |
ENSDART00000186322
|
fibromodulin a |
|
| chr5_+_32345187 Show fit | 2.48 |
ENSDART00000147132
|
complement component 9 |
|
| chr5_+_32222303 Show fit | 2.47 |
ENSDART00000051362
|
myosin heavy chain 4 |
|
| chr12_+_25085751 Show fit | 2.43 |
ENSDART00000170466
|
GTP cyclohydrolase 2 |
|
| chr21_+_7582036 Show fit | 2.28 |
ENSDART00000135485
ENSDART00000027268 |
orthopedia homeobox a |
|
| chr12_-_16636627 Show fit | 2.22 |
ENSDART00000128811
|
si:dkey-239j18.3 |
Network of associatons between targets according to the STRING database.
First level regulatory network of ikzf1
Gene Ontology Analysis
Gene overrepresentation in biological process category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.1 | 3.9 | GO:0006096 | glycolytic process(GO:0006096) |
| 0.1 | 3.5 | GO:0044243 | collagen catabolic process(GO:0030574) multicellular organism catabolic process(GO:0044243) |
| 0.5 | 3.3 | GO:0006172 | ADP biosynthetic process(GO:0006172) purine nucleoside diphosphate biosynthetic process(GO:0009136) purine ribonucleoside diphosphate biosynthetic process(GO:0009180) |
| 0.8 | 2.5 | GO:0006957 | complement activation, alternative pathway(GO:0006957) |
| 0.0 | 2.5 | GO:0098742 | cell-cell adhesion via plasma-membrane adhesion molecules(GO:0098742) |
| 0.6 | 2.4 | GO:0046654 | tetrahydrofolate biosynthetic process(GO:0046654) |
| 0.6 | 2.4 | GO:0061549 | sympathetic ganglion development(GO:0061549) |
| 0.4 | 2.3 | GO:0035176 | mammillary body development(GO:0021767) social behavior(GO:0035176) intraspecies interaction between organisms(GO:0051703) |
| 0.2 | 2.2 | GO:0009954 | proximal/distal pattern formation(GO:0009954) |
| 0.1 | 2.2 | GO:0050650 | chondroitin sulfate proteoglycan biosynthetic process(GO:0050650) |
Gene overrepresentation in cellular component category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 26.3 | GO:0005615 | extracellular space(GO:0005615) |
| 0.0 | 5.7 | GO:0030017 | sarcomere(GO:0030017) |
| 0.0 | 4.0 | GO:0005581 | collagen trimer(GO:0005581) |
| 0.8 | 2.5 | GO:0044216 | other organism(GO:0044215) other organism cell(GO:0044216) other organism part(GO:0044217) other organism cell membrane(GO:0044218) other organism membrane(GO:0044279) |
| 0.0 | 2.3 | GO:0042383 | sarcolemma(GO:0042383) |
| 0.0 | 2.2 | GO:0034707 | chloride channel complex(GO:0034707) |
| 0.1 | 2.0 | GO:0030867 | rough endoplasmic reticulum membrane(GO:0030867) |
| 0.0 | 1.9 | GO:0016459 | myosin complex(GO:0016459) |
| 0.2 | 1.7 | GO:0005945 | 6-phosphofructokinase complex(GO:0005945) |
| 0.0 | 1.6 | GO:0005882 | intermediate filament(GO:0005882) |
Gene overrepresentation in molecular function category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 4.5 | GO:0004197 | cysteine-type endopeptidase activity(GO:0004197) |
| 0.7 | 3.9 | GO:0004743 | pyruvate kinase activity(GO:0004743) |
| 0.3 | 3.3 | GO:0004017 | adenylate kinase activity(GO:0004017) |
| 0.1 | 2.5 | GO:0005184 | neuropeptide hormone activity(GO:0005184) |
| 0.2 | 2.4 | GO:0016918 | retinal binding(GO:0016918) |
| 0.2 | 2.4 | GO:0019238 | cyclohydrolase activity(GO:0019238) |
| 0.1 | 1.9 | GO:0050840 | extracellular matrix binding(GO:0050840) |
| 0.4 | 1.8 | GO:0008743 | L-threonine 3-dehydrogenase activity(GO:0008743) |
| 0.2 | 1.7 | GO:0003872 | 6-phosphofructokinase activity(GO:0003872) |
| 0.2 | 1.7 | GO:0032036 | myosin heavy chain binding(GO:0032036) |
Gene overrepresentation in curated gene sets: canonical pathways category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.2 | 3.9 | PID ALK1 PATHWAY | ALK1 signaling events |
| 0.2 | 3.5 | PID SYNDECAN 4 PATHWAY | Syndecan-4-mediated signaling events |
| 0.0 | 3.2 | NABA ECM AFFILIATED | Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins |
| 0.1 | 2.6 | SIG REGULATION OF THE ACTIN CYTOSKELETON BY RHO GTPASES | Genes related to regulation of the actin cytoskeleton |
| 0.1 | 2.2 | PID HNF3B PATHWAY | FOXA2 and FOXA3 transcription factor networks |
| 0.2 | 1.7 | PID SYNDECAN 2 PATHWAY | Syndecan-2-mediated signaling events |
| 0.1 | 1.7 | PID INTEGRIN2 PATHWAY | Beta2 integrin cell surface interactions |
| 0.0 | 1.7 | PID ERBB1 INTERNALIZATION PATHWAY | Internalization of ErbB1 |
| 0.0 | 1.4 | PID ERA GENOMIC PATHWAY | Validated nuclear estrogen receptor alpha network |
| 0.0 | 1.2 | NABA BASEMENT MEMBRANES | Genes encoding structural components of basement membranes |
Gene overrepresentation in curated gene sets: REACTOME pathways category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.1 | 3.4 | REACTOME COMPLEMENT CASCADE | Genes involved in Complement cascade |
| 0.2 | 3.3 | REACTOME SYNTHESIS AND INTERCONVERSION OF NUCLEOTIDE DI AND TRIPHOSPHATES | Genes involved in Synthesis and interconversion of nucleotide di- and triphosphates |
| 0.0 | 2.0 | REACTOME INTEGRIN CELL SURFACE INTERACTIONS | Genes involved in Integrin cell surface interactions |
| 0.2 | 1.9 | REACTOME HORMONE SENSITIVE LIPASE HSL MEDIATED TRIACYLGLYCEROL HYDROLYSIS | Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis |
| 0.2 | 1.7 | REACTOME DEGRADATION OF THE EXTRACELLULAR MATRIX | Genes involved in Degradation of the extracellular matrix |
| 0.2 | 1.7 | REACTOME GAMMA CARBOXYLATION TRANSPORT AND AMINO TERMINAL CLEAVAGE OF PROTEINS | Genes involved in Gamma-carboxylation, transport, and amino-terminal cleavage of proteins |
| 0.1 | 1.7 | REACTOME A TETRASACCHARIDE LINKER SEQUENCE IS REQUIRED FOR GAG SYNTHESIS | Genes involved in A tetrasaccharide linker sequence is required for GAG synthesis |
| 0.0 | 1.6 | REACTOME SIGNALING BY RHO GTPASES | Genes involved in Signaling by Rho GTPases |
| 0.1 | 1.3 | REACTOME TRAFFICKING AND PROCESSING OF ENDOSOMAL TLR | Genes involved in Trafficking and processing of endosomal TLR |
| 0.1 | 1.3 | REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS | Genes involved in Cell-extracellular matrix interactions |